Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for mafb+mafba+nrl

Z-value: 2.39

Motif logo

logo of

Transcription factors associated with mafb+mafba+nrl

Gene Symbol Gene ID Gene Info
mafba
ENSDARG00000017121 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
mafb
ENSDARG00000076520 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b)
nrl
ENSDARG00000100466 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nrldr11_v1_chr20_+_661037_6610370.831.3e-05Click!
mafbdr11_v1_chr25_+_36674715_366747150.812.4e-05Click!
mafbadr11_v1_chr23_-_3409140_3409140-0.282.5e-01Click!

Activity profile of mafb+mafba+nrl motif

Sorted Z-values of mafb+mafba+nrl motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22318511 8.99 ENSDART00000129295
crygm2d2
crystallin, gamma M2d2
chr25_-_3503164 6.65 ENSDART00000191477
ENSDART00000186345
ENSDART00000180199
PRKAR2B
si:ch211-272n13.7
chr9_-_22232902 6.60 ENSDART00000101845
crygm2d5
crystallin, gamma M2d5
chr1_+_44439661 6.59 ENSDART00000100309
crybb1l2
crystallin, beta B1, like 2
chr14_+_49135264 5.97 ENSDART00000084119
si:ch1073-44g3.1
si:ch1073-44g3.1
chr3_-_61185746 5.91 ENSDART00000028219
pvalb4
parvalbumin 4
chr11_-_1291012 5.31 ENSDART00000158390
atp2b2
ATPase plasma membrane Ca2+ transporting 2
chr3_-_61203203 5.23 ENSDART00000171787
pvalb1
parvalbumin 1
chr8_+_6954984 4.80 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr25_-_4482449 4.61 ENSDART00000056278
ENSDART00000149425
slc25a22a
solute carrier family 25 member 22a
chr24_-_41312459 4.05 ENSDART00000041349
crygn2
crystallin, gamma N2
chr9_-_22240052 4.02 ENSDART00000111109
crygm2d9
crystallin, gamma M2d9
chr8_-_14052349 3.93 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr10_-_7858553 3.85 ENSDART00000182010
inpp5ja
inositol polyphosphate-5-phosphatase Ja
chr9_-_22147567 3.83 ENSDART00000110941
crygm2d14
crystallin, gamma M2d14
chr17_+_9310259 3.77 ENSDART00000186158
ENSDART00000190329
NPAS3
neuronal PAS domain protein 3
chr1_-_44434707 3.63 ENSDART00000110148
cryba1l2
crystallin, beta A1, like 2
chr3_-_50443607 3.49 ENSDART00000074036
rcvrna
recoverin a
chr19_-_5345930 3.49 ENSDART00000066620
ENSDART00000151398
krtt1c19e
keratin type 1 c19e
chr14_+_904850 3.37 ENSDART00000161847
si:ch73-208h1.1
si:ch73-208h1.1
chr23_+_21067684 3.37 ENSDART00000132066
kcnab2b
potassium voltage-gated channel, shaker-related subfamily, beta member 2 b
chr5_-_71722257 3.36 ENSDART00000013404
ak1
adenylate kinase 1
chr7_-_26087807 3.28 ENSDART00000052989
ache
acetylcholinesterase
chr13_+_3954540 3.26 ENSDART00000092646
lrrc73
leucine rich repeat containing 73
chr24_-_26283359 3.22 ENSDART00000128618
and1
actinodin1
chr6_-_60147517 3.18 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr1_-_59287410 2.99 ENSDART00000158011
ENSDART00000170580
col5a3b
collagen, type V, alpha 3b
chr23_+_2542158 2.97 ENSDART00000182197
LO017835.1

chr15_+_2559875 2.89 ENSDART00000178505
SH2B2
SH2B adaptor protein 2
chr13_+_24755049 2.88 ENSDART00000134102
col17a1b
collagen, type XVII, alpha 1b
chr8_-_23416362 2.84 ENSDART00000063005
gpr173
G protein-coupled receptor 173
chr5_+_36614196 2.77 ENSDART00000150574
nova1
neuro-oncological ventral antigen 1
chr8_+_24854600 2.75 ENSDART00000156570
slc6a17
solute carrier family 6 (neutral amino acid transporter), member 17
chr14_-_52521460 2.74 ENSDART00000172110
GPR151
G protein-coupled receptor 151
chr15_+_16897554 2.73 ENSDART00000154679
ypel2b
yippee-like 2b
chr4_+_12113105 2.73 ENSDART00000182399
tmem178b
transmembrane protein 178B
chr14_+_1365097 2.71 ENSDART00000083797
ENSDART00000176087
tbc1d9
TBC1 domain family, member 9 (with GRAM domain)
chr21_+_41697552 2.71 ENSDART00000169511
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr15_+_45640906 2.67 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr17_-_608857 2.63 ENSDART00000163431
KLHL28
kelch like family member 28
chr24_-_31942656 2.62 ENSDART00000180308
ENSDART00000016879
c1ql3a
complement component 1, q subcomponent-like 3a
chr19_-_5254699 2.60 ENSDART00000081951
stx1b
syntaxin 1B
chr7_+_58686860 2.60 ENSDART00000052332
penkb
proenkephalin b
chr25_-_3503458 2.59 ENSDART00000173269
PRKAR2B
si:ch211-272n13.7
chr7_+_72882446 2.57 ENSDART00000131113
ENSDART00000174223
ADGRL3
adhesion G protein-coupled receptor L3
chr4_+_26496489 2.57 ENSDART00000160652
iqsec3a
IQ motif and Sec7 domain 3a
chr5_-_37935607 2.54 ENSDART00000141233
ENSDART00000084868
ENSDART00000125857
scn4bb
sodium channel, voltage-gated, type IV, beta b
chr23_-_7799184 2.52 ENSDART00000190946
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr4_-_53370 2.51 ENSDART00000180254
ENSDART00000186529
CU856344.2

chr15_+_28096152 2.48 ENSDART00000100293
ENSDART00000140092
crybb1l3
crystallin, beta B1, like 3
chr3_-_58455289 2.45 ENSDART00000052179
cdr2a
cerebellar degeneration-related protein 2a
chr5_-_70625697 2.44 ENSDART00000179538
ENSDART00000190540
CABZ01075572.1

chr22_-_38543630 2.44 ENSDART00000172029
si:ch211-126j24.1
si:ch211-126j24.1
chr1_-_21344478 2.42 ENSDART00000077805
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr9_-_296169 2.38 ENSDART00000165228
kif5aa
kinesin family member 5A, a
chr24_-_29997145 2.37 ENSDART00000135094
palmdb
palmdelphin b
chr23_-_7755373 2.37 ENSDART00000162868
PCMTD2 (1 of many)
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr16_+_34528409 2.36 ENSDART00000144718
paqr7b
progestin and adipoQ receptor family member VII, b
chr12_-_3840664 2.35 ENSDART00000160967
taok2b
TAO kinase 2b
chr1_-_5455498 2.31 ENSDART00000040368
ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr14_+_81919 2.30 ENSDART00000171444
stag3
stromal antigen 3
chr1_+_36437585 2.28 ENSDART00000189182
pou4f2
POU class 4 homeobox 2
chr19_+_58954 2.27 ENSDART00000162379
col14a1b
collagen, type XIV, alpha 1b
chr11_-_3494964 2.26 ENSDART00000162369
acap3b
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3b
chr19_+_233143 2.24 ENSDART00000175273
syngap1a
synaptic Ras GTPase activating protein 1a
chr16_+_1254390 2.22 ENSDART00000092627
ADAMTSL4
ADAMTS like 4
chr7_+_53541173 2.22 ENSDART00000159449
gramd2aa
GRAM domain containing 2Aa
chr17_-_50220228 2.21 ENSDART00000058707
jdp2a
Jun dimerization protein 2a
chr22_-_600016 2.21 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr18_+_660578 2.20 ENSDART00000161203
CELF6
si:dkey-205h23.2
chr21_-_45588720 2.20 ENSDART00000186642
ENSDART00000189531
LO018363.2

chr19_-_27261102 2.19 ENSDART00000143919
gabbr1b
gamma-aminobutyric acid (GABA) B receptor, 1b
chr3_+_61185660 2.18 ENSDART00000167114
CR352263.1

chr9_+_53707240 2.18 ENSDART00000171490
PCDH8
si:ch211-199f5.1
chr1_+_54673846 2.18 ENSDART00000145018
gprc5bb
G protein-coupled receptor, class C, group 5, member Bb
chr22_+_31821815 2.14 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr12_-_7824291 2.14 ENSDART00000148673
ENSDART00000149453
ank3b
ankyrin 3b
chr13_-_25284379 2.13 ENSDART00000124167
vcla
vinculin a
chr19_+_49721 2.12 ENSDART00000160489
col14a1b
collagen, type XIV, alpha 1b
chr8_+_53423408 2.12 ENSDART00000164792
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr22_+_17359346 2.11 ENSDART00000145434
gpr52
G protein-coupled receptor 52
chr5_-_33259079 2.10 ENSDART00000132223
ifitm1
interferon induced transmembrane protein 1
chr8_+_50983551 2.08 ENSDART00000142061
si:dkey-32e23.4
si:dkey-32e23.4
chr8_+_53464216 2.08 ENSDART00000169514
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr17_+_20605013 2.08 ENSDART00000156878
si:ch73-288o11.5
si:ch73-288o11.5
chr8_+_1082100 2.08 ENSDART00000149276
lzts3b
leucine zipper, putative tumor suppressor family member 3b
chr10_+_38775408 2.08 ENSDART00000125045
dscama
Down syndrome cell adhesion molecule a
chr4_+_19534833 2.07 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr9_+_49659114 2.06 ENSDART00000189643
CSRNP3
cysteine and serine rich nuclear protein 3
chr22_+_18816662 2.06 ENSDART00000132476
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr3_+_14317802 2.05 ENSDART00000162023
plppr2a
phospholipid phosphatase related 2a
chr23_+_44614056 2.05 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr17_-_37214196 2.05 ENSDART00000128715
kif3cb
kinesin family member 3Cb
chr21_+_3244146 2.02 ENSDART00000127740
ctif
CBP80/20-dependent translation initiation factor
chr13_+_3667230 2.01 ENSDART00000131553
ENSDART00000189841
ENSDART00000183554
ENSDART00000018737
qkib
QKI, KH domain containing, RNA binding b
chr4_-_73190246 2.01 ENSDART00000170842
LO018260.1

chr19_+_37925616 2.00 ENSDART00000148348
nxph1
neurexophilin 1
chr21_+_42226113 2.00 ENSDART00000170362
GABRB2 (1 of many)
gamma-aminobutyric acid type A receptor beta2 subunit
chr21_-_23475361 1.99 ENSDART00000156658
ENSDART00000157454
ncam1a
neural cell adhesion molecule 1a
chr14_-_2206476 1.98 ENSDART00000081870
pcdh2ab6
protocadherin 2 alpha b 6
chr3_-_30118856 1.98 ENSDART00000109953
ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr13_-_25284716 1.97 ENSDART00000039828
vcla
vinculin a
chr24_-_35707552 1.97 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr15_-_434503 1.97 ENSDART00000122286
CABZ01056629.1

chr19_-_677713 1.96 ENSDART00000025146
slc6a19a.1
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 1
chr4_+_8797197 1.96 ENSDART00000158671
sult4a1
sulfotransferase family 4A, member 1
chr12_-_314899 1.94 ENSDART00000066579
pts
6-pyruvoyltetrahydropterin synthase
chr24_-_39772045 1.94 ENSDART00000087441
GFOD1
si:ch211-276f18.2
chr6_-_13188667 1.93 ENSDART00000191654
adam23a
ADAM metallopeptidase domain 23a
chr18_+_45526585 1.93 ENSDART00000138511
kifc3
kinesin family member C3
chr2_+_52232630 1.91 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr19_-_1023051 1.91 ENSDART00000158429
tmem42b
transmembrane protein 42b
chr10_+_20113830 1.91 ENSDART00000139722
dmtn
dematin actin binding protein
chr15_-_47937204 1.89 ENSDART00000154705
si:ch1073-111c8.3
si:ch1073-111c8.3
chr23_+_45845423 1.88 ENSDART00000183404
lmnl3
lamin L3
chr20_+_52389858 1.88 ENSDART00000185863
ENSDART00000166651
arhgap39
Rho GTPase activating protein 39
chr5_-_22501663 1.87 ENSDART00000133174
si:dkey-27p18.5
si:dkey-27p18.5
chr6_-_27139396 1.87 ENSDART00000055848
zgc:103559
zgc:103559
chr5_-_12525441 1.86 ENSDART00000177490
ENSDART00000164190
ksr2
kinase suppressor of ras 2
chr9_+_25096500 1.85 ENSDART00000135074
ENSDART00000180436
ENSDART00000108629
lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr15_+_24212847 1.85 ENSDART00000155502
sez6b
seizure related 6 homolog b
chr20_-_37629084 1.84 ENSDART00000141734
hivep2a
human immunodeficiency virus type I enhancer binding protein 2a
chr13_+_3954715 1.84 ENSDART00000182477
ENSDART00000192142
ENSDART00000190962
lrrc73
leucine rich repeat containing 73
chr9_+_30890549 1.84 ENSDART00000101070
dachd
dachshund d
chr25_-_207214 1.80 ENSDART00000193448
FP236318.3

chr7_-_38612230 1.79 ENSDART00000173678
c1qtnf4
C1q and TNF related 4
chr9_-_23217196 1.79 ENSDART00000083567
kif5c
kinesin family member 5C
chr15_-_2954443 1.79 ENSDART00000161053
zgc:153184
zgc:153184
chr5_-_12524996 1.77 ENSDART00000142258
si:ch73-263f13.1
si:ch73-263f13.1
chr8_-_43456025 1.77 ENSDART00000001092
ENSDART00000140618
ncor2
nuclear receptor corepressor 2
chr9_+_21407987 1.77 ENSDART00000145627
gja3
gap junction protein, alpha 3
chr5_-_32092856 1.76 ENSDART00000086181
ENSDART00000181677
cabp7b
calcium binding protein 7b
chr5_-_28915130 1.76 ENSDART00000078592
npdc1b
neural proliferation, differentiation and control, 1b
chr22_-_31517300 1.76 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr23_+_45845159 1.75 ENSDART00000023944
lmnl3
lamin L3
chr1_-_43915423 1.75 ENSDART00000181915
ENSDART00000113673
scpp5
secretory calcium-binding phosphoprotein 5
chr5_-_21030934 1.74 ENSDART00000133461
ENSDART00000098667
camk2b1
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr9_+_14023386 1.74 ENSDART00000140199
ENSDART00000124267
si:ch211-67e16.4
si:ch211-67e16.4
chr18_+_3630331 1.73 ENSDART00000159059
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr23_-_3674443 1.73 ENSDART00000134830
ENSDART00000057422
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr6_-_15604157 1.73 ENSDART00000141597
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr3_+_16566361 1.72 ENSDART00000132869
ENSDART00000080771
slc6a16a
solute carrier family 6, member 16a
chr17_-_43399896 1.72 ENSDART00000156033
ENSDART00000156418
itpk1b
inositol-tetrakisphosphate 1-kinase b
chr2_-_24444838 1.72 ENSDART00000147885
ENSDART00000164720
kcnn1a
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a
chr16_+_10346277 1.71 ENSDART00000081092
si:dkeyp-77h1.4
si:dkeyp-77h1.4
chr1_+_49266886 1.70 ENSDART00000137179
caly
calcyon neuron-specific vesicular protein
chr22_+_2254972 1.70 ENSDART00000144906
znf1157
zinc finger protein 1157
chr15_-_47193564 1.70 ENSDART00000172453
LSAMP
limbic system-associated membrane protein
chr17_+_30450163 1.67 ENSDART00000104257
lpin1
lipin 1
chr18_-_85294 1.67 ENSDART00000044387
gabpb1
GA binding protein transcription factor, beta subunit 1
chr4_+_68562464 1.66 ENSDART00000192954
BX548011.4

chr6_-_57938043 1.64 ENSDART00000171073
tox2
TOX high mobility group box family member 2
chr11_+_30161168 1.63 ENSDART00000157385
cdkl5
cyclin-dependent kinase-like 5
chr23_-_45049044 1.63 ENSDART00000067630
SH3GL2 (1 of many)
SH3 domain containing GRB2 like 2, endophilin A1
chr23_-_30954738 1.62 ENSDART00000188996
osbpl2a
oxysterol binding protein-like 2a
chr22_+_2143107 1.62 ENSDART00000172339
ENSDART00000161280
ENSDART00000163671
ENSDART00000172090
ENSDART00000163573
znf1164
zinc finger protein 1164
chr16_+_10841163 1.61 ENSDART00000065467
dedd1
death effector domain-containing 1
chr16_-_43356018 1.60 ENSDART00000181683
FO704821.1

chr20_-_53321499 1.60 ENSDART00000179894
ENSDART00000127427
ENSDART00000084952
wasf1
WAS protein family, member 1
chr14_-_52542928 1.60 ENSDART00000075749
ppp2r2ba
protein phosphatase 2, regulatory subunit B, beta a
chr6_+_112579 1.60 ENSDART00000034505
ap1m2
adaptor-related protein complex 1, mu 2 subunit
chr22_+_1137997 1.59 ENSDART00000158017
ENSDART00000183226
si:ch211-103a14.5
si:ch211-103a14.5
chr8_+_29267093 1.58 ENSDART00000077647
grid2
glutamate receptor, ionotropic, delta 2
chr24_-_31452875 1.58 ENSDART00000187381
ENSDART00000185128
cngb3.2
cyclic nucleotide gated channel beta 3, tandem duplicate 2
chr20_-_54462551 1.55 ENSDART00000171769
ENSDART00000169692
evlb
Enah/Vasp-like b
chr22_+_635813 1.55 ENSDART00000179067
CU856139.1

chr14_-_44841335 1.55 ENSDART00000173011
GRXCR1
si:dkey-109l4.6
chr9_-_22069364 1.54 ENSDART00000101938
crygm2b
crystallin, gamma M2b
chr5_+_45976130 1.54 ENSDART00000175670
sv2c
synaptic vesicle glycoprotein 2C
chr18_-_1228688 1.52 ENSDART00000064403
nptnb
neuroplastin b
chr19_-_6134802 1.51 ENSDART00000140051
cica
capicua transcriptional repressor a
chr13_-_11644806 1.51 ENSDART00000169953
dctn1b
dynactin 1b
chr5_-_68022631 1.51 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr23_-_270847 1.50 ENSDART00000191867
anks1aa
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr8_-_22288258 1.50 ENSDART00000140978
ENSDART00000100046
si:ch211-147a11.3
si:ch211-147a11.3
chr3_+_20012891 1.50 ENSDART00000078974
tmub2
transmembrane and ubiquitin-like domain containing 2
chr1_+_52690448 1.49 ENSDART00000150326
osbp
oxysterol binding protein
chr14_-_1454045 1.49 ENSDART00000161460
pmt
phosphoethanolamine methyltransferase
chr6_+_103361 1.49 ENSDART00000151899
ldlrb
low density lipoprotein receptor b
chr21_+_382400 1.49 ENSDART00000190785
ENSDART00000124615
rad23b
RAD23 homolog B, nucleotide excision repair protein
chr14_-_30642819 1.49 ENSDART00000078154
npas4a
neuronal PAS domain protein 4a
chr18_-_12612699 1.49 ENSDART00000090335
hipk2
homeodomain interacting protein kinase 2
chr3_-_53465223 1.49 ENSDART00000057123
ENSDART00000125515
ENSDART00000143096
nr5a5
nuclear receptor subfamily 5, group A, member 5
chr10_+_35953068 1.48 ENSDART00000015279
rtn4rl1a
reticulon 4 receptor-like 1a
chr6_-_58828398 1.48 ENSDART00000090634
kif5ab
kinesin family member 5A, b
chr18_+_10840071 1.48 ENSDART00000014496
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr4_+_72798545 1.48 ENSDART00000181727
MYRFL
myelin regulatory factor-like
chr17_-_43286903 1.47 ENSDART00000176637
EML5
si:dkey-1f12.3
chr2_-_56635744 1.47 ENSDART00000167790
ENSDART00000168160
pip5k1cb
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b
chr6_-_10776254 1.45 ENSDART00000184008
gpr155b
G protein-coupled receptor 155b
chr12_-_45533034 1.45 ENSDART00000113004
CABZ01068356.1

chr6_-_24358732 1.45 ENSDART00000159595
ephx4
epoxide hydrolase 4
chr4_-_149334 1.45 ENSDART00000163280
tbk1
TANK-binding kinase 1
chr17_-_12385308 1.45 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr1_+_29281764 1.44 ENSDART00000112106
fam155a
family with sequence similarity 155, member A
chr6_-_15604417 1.43 ENSDART00000157817
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr19_+_56351 1.43 ENSDART00000168334
col14a1b
collagen, type XIV, alpha 1b
chr19_+_823945 1.43 ENSDART00000142287
ppp1r18
protein phosphatase 1, regulatory subunit 18
chr12_-_11570 1.42 ENSDART00000186179
shisa6
shisa family member 6
chr23_+_45579497 1.42 ENSDART00000110381
egr4
early growth response 4

Network of associatons between targets according to the STRING database.

First level regulatory network of mafb+mafba+nrl

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.9 2.7 GO:0015824 proline transport(GO:0015824)
0.8 3.3 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.8 5.7 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.7 4.1 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.7 2.0 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.6 2.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.6 1.9 GO:0000256 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
0.6 1.9 GO:2000402 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.6 3.4 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.6 4.4 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.5 2.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.5 2.7 GO:0097272 ammonia homeostasis(GO:0097272)
0.5 2.6 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.5 1.5 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.5 3.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.5 4.6 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.4 1.8 GO:0003161 cardiac conduction system development(GO:0003161)
0.4 1.3 GO:0051580 regulation of neurotransmitter uptake(GO:0051580)
0.4 2.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.4 1.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.4 1.2 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.4 3.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.4 1.2 GO:1901993 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.3 1.4 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.3 3.8 GO:0036368 cone photoresponse recovery(GO:0036368)
0.3 1.4 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.3 1.3 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.3 42.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.3 2.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.3 1.8 GO:0043584 nose development(GO:0043584)
0.3 1.5 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.3 2.1 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.3 1.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.3 0.8 GO:0051583 synaptic transmission, dopaminergic(GO:0001963) norepinephrine transport(GO:0015874) dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.3 1.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 0.8 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.3 2.2 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.3 2.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.3 1.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 1.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600) regulation of glucose import(GO:0046324)
0.3 2.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.3 2.0 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.3 1.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 1.0 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.2 1.2 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.2 0.7 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.2 2.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 2.0 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 0.6 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 1.1 GO:0035608 protein deglutamylation(GO:0035608)
0.2 0.6 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 1.3 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2 2.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 3.1 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 1.4 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 1.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 3.2 GO:0048899 anterior lateral line development(GO:0048899)
0.2 0.6 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.2 0.6 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.2 1.9 GO:0007608 sensory perception of smell(GO:0007608)
0.2 1.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.2 0.9 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 0.7 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.2 1.8 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 1.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.2 2.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.2 1.5 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.2 0.8 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.2 0.5 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.2 1.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.5 GO:0035992 tendon formation(GO:0035992)
0.2 1.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.2 2.1 GO:0045162 neuronal ion channel clustering(GO:0045161) clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.6 GO:0099565 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.1 0.6 GO:0016038 absorption of visible light(GO:0016038)
0.1 0.7 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 1.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.1 GO:0044211 CTP salvage(GO:0044211)
0.1 0.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 3.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.3 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 3.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.3 GO:0043901 negative regulation of multi-organism process(GO:0043901)
0.1 1.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.3 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.1 0.8 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 2.4 GO:0001556 oocyte maturation(GO:0001556)
0.1 0.7 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.4 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 1.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.9 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 0.7 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 2.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 1.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 2.0 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.6 GO:0021767 mammillary body development(GO:0021767)
0.1 1.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.7 GO:0090075 relaxation of muscle(GO:0090075)
0.1 3.0 GO:0015872 dopamine transport(GO:0015872)
0.1 0.4 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.1 1.7 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 2.7 GO:0051923 sulfation(GO:0051923)
0.1 4.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 3.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.4 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 1.0 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 7.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.7 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.6 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 2.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.4 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 0.2 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 1.6 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.8 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.6 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.2 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.1 1.1 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.7 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.7 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 0.4 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.1 0.4 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 0.3 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 1.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.2 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.1 0.3 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 1.7 GO:0051289 protein homotetramerization(GO:0051289)
0.1 1.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.6 GO:0030431 sleep(GO:0030431)
0.1 1.9 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 10.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.7 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.2 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 1.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.6 GO:0014074 response to purine-containing compound(GO:0014074) response to ATP(GO:0033198) response to organophosphorus(GO:0046683)
0.1 1.9 GO:0072348 sulfur compound transport(GO:0072348)
0.1 0.5 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 1.1 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.6 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.5 GO:0006984 ER-nucleus signaling pathway(GO:0006984)
0.0 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 2.2 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 1.3 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 1.3 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.3 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.4 GO:1902686 positive regulation of mitochondrial membrane permeability(GO:0035794) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 1.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.3 GO:0035094 response to nicotine(GO:0035094)
0.0 1.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 4.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.0 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.6 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 1.7 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 2.7 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 1.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.7 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 1.3 GO:0046058 cAMP biosynthetic process(GO:0006171) cAMP metabolic process(GO:0046058)
0.0 2.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 3.1 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 1.4 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.2 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 4.0 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.7 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.5 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.5 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0033151 V(D)J recombination(GO:0033151)
0.0 1.0 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.3 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 1.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 5.5 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.4 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 1.2 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108) peptidyl-tyrosine modification(GO:0018212)
0.0 3.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0032098 regulation of appetite(GO:0032098)
0.0 2.7 GO:0033674 positive regulation of kinase activity(GO:0033674)
0.0 2.2 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0009190 cyclic nucleotide biosynthetic process(GO:0009190)
0.0 0.4 GO:0050890 cognition(GO:0050890)
0.0 1.5 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:1902623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.6 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.8 GO:0099531 presynaptic process involved in chemical synaptic transmission(GO:0099531)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.0 0.6 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 1.1 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.3 GO:0050868 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.4 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.3 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.5 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.1 GO:0046620 regulation of organ growth(GO:0046620)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 2.4 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.4 GO:0006821 chloride transport(GO:0006821)
0.0 1.9 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 2.2 GO:0070062 extracellular exosome(GO:0070062)
0.4 2.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 1.0 GO:0044316 cone cell pedicle(GO:0044316)
0.3 0.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 1.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 2.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.3 2.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.3 3.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 2.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 3.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 3.1 GO:0031209 SCAR complex(GO:0031209)
0.2 0.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 8.3 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.1 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 3.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.8 GO:0005922 connexon complex(GO:0005922)
0.1 1.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.3 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 3.2 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 10.0 GO:0005871 kinesin complex(GO:0005871)
0.1 0.9 GO:0016586 RSC complex(GO:0016586)
0.1 0.8 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 3.9 GO:0043679 axon terminus(GO:0043679)
0.1 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.0 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.3 GO:0008278 cohesin complex(GO:0008278)
0.1 0.4 GO:0043073 germ cell nucleus(GO:0043073)
0.1 1.1 GO:0005921 gap junction(GO:0005921)
0.1 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 4.8 GO:0042383 sarcolemma(GO:0042383)
0.1 0.5 GO:0016234 inclusion body(GO:0016234)
0.1 0.7 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.2 GO:1990745 EARP complex(GO:1990745)
0.1 3.1 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 3.4 GO:0030027 lamellipodium(GO:0030027)
0.1 4.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.2 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 4.1 GO:0048786 presynaptic active zone(GO:0048786)
0.1 4.8 GO:0001726 ruffle(GO:0001726)
0.1 1.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 5.3 GO:0005581 collagen trimer(GO:0005581)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.9 GO:0030175 filopodium(GO:0030175)
0.0 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.3 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 6.3 GO:0070382 exocytic vesicle(GO:0070382)
0.0 3.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 4.5 GO:0045202 synapse(GO:0045202)
0.0 1.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.4 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 2.1 GO:0099503 secretory vesicle(GO:0099503)
0.0 0.5 GO:0030426 growth cone(GO:0030426)
0.0 3.8 GO:0030424 axon(GO:0030424)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 5.5 GO:0043005 neuron projection(GO:0043005)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 1.3 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.7 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 1.1 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 20.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.9 2.7 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.6 4.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.5 3.3 GO:0004104 cholinesterase activity(GO:0004104)
0.5 43.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 1.9 GO:0050897 cobalt ion binding(GO:0050897)
0.4 2.1 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 1.2 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.4 1.1 GO:0046978 TAP1 binding(GO:0046978)
0.4 1.8 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.3 3.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 1.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 2.6 GO:0031628 opioid receptor binding(GO:0031628)
0.3 1.0 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 9.2 GO:0030165 PDZ domain binding(GO:0030165)
0.3 0.8 GO:0005330 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330) norepinephrine transmembrane transporter activity(GO:0005333) norepinephrine:sodium symporter activity(GO:0005334)
0.3 2.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 3.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.3 2.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 3.2 GO:0015295 solute:proton symporter activity(GO:0015295)
0.2 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.2 0.9 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 2.0 GO:0008494 translation activator activity(GO:0008494)
0.2 1.9 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 0.6 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.2 0.9 GO:0005112 Notch binding(GO:0005112)
0.2 1.0 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.2 1.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 1.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 1.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 2.5 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 1.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.7 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.2 5.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.5 GO:0019777 Atg12 transferase activity(GO:0019777)
0.2 9.5 GO:0044325 ion channel binding(GO:0044325)
0.2 0.5 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 0.5 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765) inositol trisphosphate kinase activity(GO:0051766)
0.2 2.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 1.6 GO:0005522 profilin binding(GO:0005522)
0.2 1.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 1.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 1.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.0 GO:0005035 death receptor activity(GO:0005035)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 4.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.8 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.7 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.4 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 0.8 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 1.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 3.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.0 GO:0030507 spectrin binding(GO:0030507)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 3.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.5 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 1.5 GO:0070628 proteasome binding(GO:0070628)
0.1 1.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 3.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 4.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0043621 protein self-association(GO:0043621)
0.1 1.9 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 1.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.5 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 1.9 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 3.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.1 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.9 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 1.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.2 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.5 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 2.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.1 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 11.2 GO:0015293 symporter activity(GO:0015293)
0.1 0.2 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.1 0.9 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 3.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.5 GO:0031267 small GTPase binding(GO:0031267)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 7.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.0 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 4.6 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.5 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.2 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.3 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 1.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 2.2 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 1.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.9 GO:0017046 peptide hormone binding(GO:0017046)
0.0 2.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.5 GO:0016502 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) purinergic receptor activity(GO:0035586) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 9.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 4.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 2.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.4 GO:0019902 phosphatase binding(GO:0019902)
0.0 22.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.4 GO:0000149 SNARE binding(GO:0000149)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.7 GO:0005496 steroid binding(GO:0005496)
0.0 1.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.7 GO:0016917 GABA receptor activity(GO:0016917)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 5.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 1.4 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 2.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.3 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.0 PID ARF 3PATHWAY Arf1 pathway
0.1 2.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.5 2.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 6.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 4.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 1.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 3.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 1.8 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.2 4.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 0.7 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.2 2.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 0.6 REACTOME OPSINS Genes involved in Opsins
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.8 REACTOME KINESINS Genes involved in Kinesins
0.1 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 2.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions