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PRJEB1986: zebrafish developmental stages transcriptome

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Results for mecom

Z-value: 1.11

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Transcription factors associated with mecom

Gene Symbol Gene ID Gene Info
mecom
ENSDARG00000060808 MDS1 and EVI1 complex locus

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mecomdr11_v1_chr15_-_35406564_35406564-0.821.4e-05Click!

Activity profile of mecom motif

Sorted Z-values of mecom motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_26304386 3.59 ENSDART00000175416
otos
otospiralin
chr3_-_61203203 2.99 ENSDART00000171787
pvalb1
parvalbumin 1
chr2_-_51794472 2.80 ENSDART00000186652
BX908782.3

chr10_-_22854758 2.74 ENSDART00000079449
and3
actinodin3
chr23_+_40410644 2.28 ENSDART00000056328
elovl4b
ELOVL fatty acid elongase 4b
chr13_+_3252950 2.08 ENSDART00000020671
prph2b
peripherin 2b (retinal degeneration, slow)
chr25_-_12923482 1.92 ENSDART00000161754
CR450808.1

chr14_+_32838110 1.79 ENSDART00000158077
arr3b
arrestin 3b, retinal (X-arrestin)
chr17_-_125091 1.68 ENSDART00000158825
actc1b
actin, alpha, cardiac muscle 1b
chr3_-_22228602 1.62 ENSDART00000017750
myl4
myosin, light chain 4, alkali; atrial, embryonic
chr14_+_35691889 1.52 ENSDART00000074685
glrbb
glycine receptor, beta b
chr10_-_8046764 1.48 ENSDART00000099031
zgc:136254
zgc:136254
chr15_+_22311803 1.47 ENSDART00000150182
hepacama
hepatic and glial cell adhesion molecule a
chr10_-_8053385 1.46 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr9_+_13714379 1.40 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr14_+_32837914 1.39 ENSDART00000158888
arr3b
arrestin 3b, retinal (X-arrestin)
chr10_-_8053753 1.26 ENSDART00000162289
si:ch211-251f6.7
si:ch211-251f6.7
chr8_-_14121634 1.22 ENSDART00000184946
bgna
biglycan a
chr22_-_15385442 1.22 ENSDART00000090975
tmem264
transmembrane protein 264
chr8_+_34731982 1.21 ENSDART00000066050
hpdb
4-hydroxyphenylpyruvate dioxygenase b
chr21_+_7582036 1.21 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr24_-_15648636 1.16 ENSDART00000136200
cbln2b
cerebellin 2b precursor
chr7_-_38340674 1.12 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr6_-_46861676 1.06 ENSDART00000188712
ENSDART00000190148
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr7_-_8374950 1.06 ENSDART00000057101
aep1
aerolysin-like protein
chr10_-_31782616 1.05 ENSDART00000128839
fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr10_+_11309814 1.04 ENSDART00000145673
si:ch211-126i22.5
si:ch211-126i22.5
chr11_-_13126505 1.03 ENSDART00000158377
elovl1b
ELOVL fatty acid elongase 1b
chr6_-_40697585 1.02 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr14_-_3070613 1.01 ENSDART00000193729
ENSDART00000090196
slc35a4
solute carrier family 35, member A4
chr8_-_31369161 1.00 ENSDART00000019937
gadd45ga
growth arrest and DNA-damage-inducible, gamma a
chr8_+_20880848 0.98 ENSDART00000134488
ENSDART00000138605
ENSDART00000192234
si:ch73-196i15.3
si:ch73-196i15.3
chr1_+_31110817 0.95 ENSDART00000137863
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr6_-_50203682 0.94 ENSDART00000083999
ENSDART00000143050
raly
RALY heterogeneous nuclear ribonucleoprotein
chr6_-_10963887 0.92 ENSDART00000151102
notum2
notum pectinacetylesterase 2
chr14_-_6527010 0.91 ENSDART00000125058
nipsnap3a
nipsnap homolog 3A (C. elegans)
chr25_-_12935065 0.90 ENSDART00000167362
ccl39.7
chemokine (C-C motif) ligand 39, duplicate 7
chr18_+_8346920 0.89 ENSDART00000083421
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr18_-_17485419 0.86 ENSDART00000018764
foxl1
forkhead box L1
chr21_+_15704556 0.86 ENSDART00000024858
ENSDART00000146909
chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr3_-_32817274 0.84 ENSDART00000142582
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr15_+_7054754 0.83 ENSDART00000149800
foxl2a
forkhead box L2a
chr5_-_10946232 0.81 ENSDART00000163139
ENSDART00000031265
rtn4r
reticulon 4 receptor
chr22_+_10752511 0.80 ENSDART00000081188
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr10_-_30785501 0.79 ENSDART00000020054
opcml
opioid binding protein/cell adhesion molecule-like
chr20_-_34801181 0.78 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr14_+_36738069 0.76 ENSDART00000105590
tdo2a
tryptophan 2,3-dioxygenase a
chr18_+_16330025 0.75 ENSDART00000142353
nts
neurotensin
chr22_+_10752787 0.73 ENSDART00000186542
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr6_-_29195642 0.73 ENSDART00000078625
dpt
dermatopontin
chr4_-_16353733 0.72 ENSDART00000186785
lum
lumican
chr4_+_41227127 0.72 ENSDART00000136445
si:dkey-16p19.5
si:dkey-16p19.5
chr2_-_43168292 0.72 ENSDART00000132588
crema
cAMP responsive element modulator a
chr12_-_31484677 0.72 ENSDART00000066578
tectb
tectorin beta
chr6_+_8176486 0.71 ENSDART00000193308
nfil3-5
nuclear factor, interleukin 3 regulated, member 5
chr25_-_12935424 0.70 ENSDART00000160217
ccl39.7
chemokine (C-C motif) ligand 39, duplicate 7
chr4_-_12104421 0.69 ENSDART00000139561
mrps33
mitochondrial ribosomal protein S33
chr22_-_29242347 0.69 ENSDART00000040761
pvalb7
parvalbumin 7
chr24_+_23742690 0.68 ENSDART00000130162
TCF24
transcription factor 24
chr7_-_38612230 0.68 ENSDART00000173678
c1qtnf4
C1q and TNF related 4
chr18_+_16246806 0.68 ENSDART00000142584
alx1
ALX homeobox 1
chr7_+_21887787 0.68 ENSDART00000162252
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr13_+_10232695 0.67 ENSDART00000080805
six2a
SIX homeobox 2a
chr11_-_13126969 0.66 ENSDART00000169052
ENSDART00000190120
elovl1b
ELOVL fatty acid elongase 1b
chr17_-_30702411 0.66 ENSDART00000114358
zgc:194392
zgc:194392
chr20_+_26538137 0.64 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr10_-_29120515 0.63 ENSDART00000162016
ENSDART00000149140
zpld1a
zona pellucida-like domain containing 1a
chr15_-_23647078 0.63 ENSDART00000059366
ckmb
creatine kinase, muscle b
chr2_-_24981356 0.62 ENSDART00000111212
nck1a
NCK adaptor protein 1a
chr4_+_7391110 0.60 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr7_+_21887307 0.59 ENSDART00000052871
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr22_-_17256573 0.59 ENSDART00000136119
ENSDART00000062891
nphs2
nephrosis 2, idiopathic, steroid-resistant (podocin)
chr9_+_10014817 0.58 ENSDART00000132065
nxph2a
neurexophilin 2a
chr6_-_31806345 0.58 ENSDART00000149369
si:dkey-209n16.2
si:dkey-209n16.2
chr11_+_39672874 0.58 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr21_-_33478164 0.57 ENSDART00000191542
si:ch73-42p12.2
si:ch73-42p12.2
chr9_-_18743012 0.57 ENSDART00000131626
tsc22d1
TSC22 domain family, member 1
chr11_-_3343463 0.56 ENSDART00000066177
tuba2
tubulin, alpha 2
chr9_+_10014514 0.55 ENSDART00000185590
nxph2a
neurexophilin 2a
chr10_+_22012389 0.54 ENSDART00000035188
kcnip1b
Kv channel interacting protein 1 b
chr21_+_6556635 0.53 ENSDART00000139598
col5a1
procollagen, type V, alpha 1
chr15_+_19646902 0.53 ENSDART00000179822
lim2.3
lens intrinsic membrane protein 2.3
chr24_-_5889878 0.52 ENSDART00000077951
pcolce2b
procollagen C-endopeptidase enhancer 2b
chr9_+_2002701 0.52 ENSDART00000082329
evx2
even-skipped homeobox 2
chr9_-_22361681 0.52 ENSDART00000129954
crygm3
crystallin, gamma M3
chr22_-_15280638 0.51 ENSDART00000063008
mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_-_25181012 0.51 ENSDART00000161585
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr7_-_59054322 0.51 ENSDART00000165390
chmp5b
charged multivesicular body protein 5b
chr11_-_15850794 0.50 ENSDART00000185946
rap1ab
RAP1A, member of RAS oncogene family b
chr22_+_11535131 0.49 ENSDART00000113930
npb
neuropeptide B
chr6_-_10964083 0.49 ENSDART00000181583
notum2
notum pectinacetylesterase 2
chr23_+_20110086 0.48 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr7_+_36552725 0.48 ENSDART00000173682
chd9
chromodomain helicase DNA binding protein 9
chr21_-_12119711 0.48 ENSDART00000131538
celf4
CUGBP, Elav-like family member 4
chr4_-_27398385 0.47 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr13_-_11699530 0.47 ENSDART00000192161
slc39a8
solute carrier family 39 (zinc transporter), member 8
chr3_+_32112004 0.47 ENSDART00000105272
zgc:173593
zgc:173593
chr4_-_8902406 0.47 ENSDART00000192962
mpped1
metallophosphoesterase domain containing 1
chr25_+_20694177 0.47 ENSDART00000073648
kxd1
KxDL motif containing 1
chr1_+_37752171 0.47 ENSDART00000183247
ENSDART00000189756
ENSDART00000139448
GALNTL6
si:ch211-15e22.3
chr20_+_2642855 0.46 ENSDART00000058775
zgc:101562
zgc:101562
chr14_+_52563794 0.45 ENSDART00000168874
rpl26
ribosomal protein L26
chr7_-_32598383 0.45 ENSDART00000111055
kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr4_+_74943111 0.44 ENSDART00000004739
nup50
nucleoporin 50
chr25_-_4148719 0.43 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr2_-_55797318 0.43 ENSDART00000158147
calr3b
calreticulin 3b
chr23_+_19213472 0.42 ENSDART00000185985
apobec2b
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b
chr10_+_21899753 0.42 ENSDART00000080155
hrh2b
histamine receptor H2b
chr19_-_42557416 0.42 ENSDART00000163217
ENSDART00000128278
ENSDART00000162304
ENSDART00000166556
si:dkey-267n13.1
si:dkey-267n13.1
chr9_-_23922778 0.42 ENSDART00000135769
col6a3
collagen, type VI, alpha 3
chr18_-_21271373 0.41 ENSDART00000060001
pnp6
purine nucleoside phosphorylase 6
chr22_+_33362552 0.41 ENSDART00000101580
nicn1
nicolin 1
chr9_+_29520696 0.40 ENSDART00000144430
fdx1
ferredoxin 1
chr18_-_6633984 0.40 ENSDART00000185241
tnni1c
troponin I, skeletal, slow c
chr17_-_24703778 0.40 ENSDART00000156061
si:ch211-15d5.12
si:ch211-15d5.12
chr19_+_17259912 0.40 ENSDART00000078951
MANEAL
si:ch211-30b16.2
chr16_+_36126310 0.39 ENSDART00000166040
ENSDART00000189802
sh3bp5b
SH3-domain binding protein 5b (BTK-associated)
chr10_+_24631976 0.38 ENSDART00000181928
slc46a3
solute carrier family 46, member 3
chr1_-_36771712 0.38 ENSDART00000148386
prmt9
protein arginine methyltransferase 9
chr23_+_44745317 0.38 ENSDART00000165654
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr2_+_15776649 0.38 ENSDART00000156535
vav3b
vav 3 guanine nucleotide exchange factor b
chr15_-_8517376 0.35 ENSDART00000186289
npas1
neuronal PAS domain protein 1
chr18_+_33237127 0.35 ENSDART00000133386
v2rc2
vomeronasal 2 receptor, c2
chr22_-_17611742 0.35 ENSDART00000144031
gpx4a
glutathione peroxidase 4a
chr1_-_45553602 0.34 ENSDART00000143664
grin2bb
glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b
chr1_-_21723329 0.34 ENSDART00000137138
si:ch211-134c9.2
si:ch211-134c9.2
chr15_+_17345609 0.34 ENSDART00000111753
vmp1
vacuole membrane protein 1
chr23_+_9220436 0.34 ENSDART00000033663
ENSDART00000139870
rps21
ribosomal protein S21
chr8_-_28349859 0.34 ENSDART00000062671
tuba8l
tubulin, alpha 8 like
chr11_+_11271959 0.34 ENSDART00000190678
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr14_+_33722950 0.34 ENSDART00000075312
apln
apelin
chr8_+_8893535 0.33 ENSDART00000139150
otud5a
OTU deubiquitinase 5a
chr11_-_23322182 0.33 ENSDART00000111289
kiss1
KiSS-1 metastasis-suppressor
chr6_-_39765546 0.33 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr7_-_59210882 0.33 ENSDART00000170330
ENSDART00000158996
nagk
N-acetylglucosamine kinase
chr7_+_30178253 0.33 ENSDART00000002075
si:ch211-107o10.3
si:ch211-107o10.3
chr1_+_58091659 0.32 ENSDART00000144190
si:ch211-114l13.1
si:ch211-114l13.1
chr21_+_21326038 0.32 ENSDART00000089898
qpctlb
glutaminyl-peptide cyclotransferase-like b
chr9_-_18742704 0.32 ENSDART00000145401
tsc22d1
TSC22 domain family, member 1
chr13_-_22961605 0.31 ENSDART00000143112
ENSDART00000057641
tspan15
tetraspanin 15
chr11_-_41130239 0.30 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr9_+_29585943 0.30 ENSDART00000185989
ENSDART00000115290
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr5_+_51026563 0.30 ENSDART00000050988
gcnt4a
glucosaminyl (N-acetyl) transferase 4, core 2, a
chr7_+_35238234 0.30 ENSDART00000178732
tppp3
tubulin polymerization-promoting protein family member 3
chr1_+_33558555 0.30 ENSDART00000018472
chmp2bb
charged multivesicular body protein 2Bb
chr11_+_35364445 0.30 ENSDART00000125766
camkvb
CaM kinase-like vesicle-associated b
chr2_-_1188707 0.29 ENSDART00000066378
CABZ01084564.1

chr8_-_25327809 0.29 ENSDART00000137242
eps8l3b
EPS8-like 3b
chr2_-_10188598 0.29 ENSDART00000189122
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr25_-_16782394 0.29 ENSDART00000019413
ndufa9a
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9a
chr4_-_685412 0.29 ENSDART00000168167
rtcb
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr5_-_33298352 0.28 ENSDART00000015076
zgc:103692
zgc:103692
chr14_-_30141162 0.28 ENSDART00000053916
mtnr1ab
melatonin receptor 1A b
chr18_-_6634424 0.28 ENSDART00000062423
ENSDART00000179955
tnni1c
troponin I, skeletal, slow c
chr2_-_20923864 0.28 ENSDART00000006870
ptgs2a
prostaglandin-endoperoxide synthase 2a
chr17_+_33495194 0.28 ENSDART00000033691
pth2
parathyroid hormone 2
chr24_+_25069609 0.27 ENSDART00000115165
amer2
APC membrane recruitment protein 2
chr9_-_14055959 0.27 ENSDART00000146675
fer1l6
fer-1-like family member 6
chr21_-_40799404 0.27 ENSDART00000147405
ENSDART00000157512
zgc:162239
zgc:162239
chr11_-_37509001 0.27 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr13_+_30172645 0.27 ENSDART00000137114
pald1b
phosphatase domain containing, paladin 1b
chr10_+_28308376 0.27 ENSDART00000191216
ptrh2
peptidyl-tRNA hydrolase 2
chr1_-_33351780 0.26 ENSDART00000178996
gyg2
glycogenin 2
chr23_+_33991509 0.26 ENSDART00000145161
fam50a
family with sequence similarity 50, member A
chr12_-_6551681 0.25 ENSDART00000145413
si:ch211-253p2.2
si:ch211-253p2.2
chr10_+_9159279 0.25 ENSDART00000064968
rasgef1bb
RasGEF domain family, member 1Bb
chr9_+_31075896 0.25 ENSDART00000188042
clybl
citrate lyase beta like
chr25_+_25438322 0.25 ENSDART00000150364
LRRC56
si:ch211-103e16.5
chr9_-_23990416 0.24 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr1_-_26045007 0.24 ENSDART00000129259
gpank1
G patch domain and ankyrin repeats 1
chr3_-_18575868 0.24 ENSDART00000122968
aqp8b
aquaporin 8b
chr16_-_14353567 0.24 ENSDART00000139859
itga10
integrin, alpha 10
chr6_-_25180438 0.24 ENSDART00000159696
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr12_+_638435 0.23 ENSDART00000152508
si:ch211-176g6.1
si:ch211-176g6.1
chr10_-_15672862 0.23 ENSDART00000109231
mamdc2b
MAM domain containing 2b
chr6_+_46259950 0.23 ENSDART00000032326
zgc:162324
zgc:162324
chr6_-_15101477 0.22 ENSDART00000187713
ENSDART00000124132
fhl2b
four and a half LIM domains 2b
chr15_+_5028608 0.22 ENSDART00000092809
abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr13_+_25421531 0.22 ENSDART00000158093
calhm2
calcium homeostasis modulator 2
chr21_+_41743493 0.21 ENSDART00000192669
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr15_+_33991928 0.21 ENSDART00000170177
vwde
von Willebrand factor D and EGF domains
chr4_-_32456788 0.21 ENSDART00000151862
si:dkey-16p6.1
si:dkey-16p6.1
chr7_-_44604540 0.21 ENSDART00000149186
tk2
thymidine kinase 2, mitochondrial
chr24_-_36337395 0.21 ENSDART00000154402
si:ch211-40k21.9
si:ch211-40k21.9
chr6_+_21062416 0.21 ENSDART00000141643
si:dkey-91f15.1
si:dkey-91f15.1
chr1_-_8020589 0.20 ENSDART00000143881
si:dkeyp-9d4.2
si:dkeyp-9d4.2
chr1_-_28089557 0.20 ENSDART00000161024
ENSDART00000167875
snapc3
small nuclear RNA activating complex, polypeptide 3
chr1_-_9644630 0.20 ENSDART00000123725
ENSDART00000161164
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B3
chr7_-_24364536 0.20 ENSDART00000064789
txn
thioredoxin
chr22_-_5958066 0.20 ENSDART00000145821
si:rp71-36a1.3
si:rp71-36a1.3
chr18_-_25276262 0.20 ENSDART00000131855
plin1
perilipin 1
chr3_-_36210344 0.20 ENSDART00000025326
csnk1da
casein kinase 1, delta a
chr22_+_19111444 0.20 ENSDART00000109655
fgf22
fibroblast growth factor 22
chr7_+_10351038 0.19 ENSDART00000173256
si:cabz01029535.1
si:cabz01029535.1
chr3_+_39579393 0.19 ENSDART00000055170
cln3
ceroid-lipofuscinosis, neuronal 3
chr23_+_30835589 0.19 ENSDART00000154145
npbwr2a
neuropeptides B/W receptor 2a
chr14_+_22591624 0.19 ENSDART00000108987
gfra4b
GDNF family receptor alpha 4b
chr1_+_34181581 0.19 ENSDART00000146042
epha6
eph receptor A6
chr1_+_58370526 0.18 ENSDART00000067775
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr14_-_15154695 0.18 ENSDART00000160677
uvssa
UV-stimulated scaffold protein A

Network of associatons between targets according to the STRING database.

First level regulatory network of mecom

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0042941 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.4 1.4 GO:1990697 protein depalmitoleylation(GO:1990697)
0.3 0.8 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 3.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 1.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 1.2 GO:0035176 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.2 4.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.5 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.4 GO:0043388 cytidine to uridine editing(GO:0016554) positive regulation of DNA binding(GO:0043388)
0.1 0.7 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.5 GO:0051591 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.3 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 0.8 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.1 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.0 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 1.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 0.3 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 2.0 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.2 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 1.0 GO:0014823 response to activity(GO:0014823)
0.1 0.4 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.9 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.6 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.5 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 1.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.2 GO:0031652 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.8 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 1.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 2.9 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0060907 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.1 GO:0071312 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.0 0.2 GO:0030194 acute-phase response(GO:0006953) positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.8 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.7 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.4 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 1.0 GO:0035138 pectoral fin morphogenesis(GO:0035138)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 0.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.6 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.5 GO:0007631 feeding behavior(GO:0007631)
0.0 0.8 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.3 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 1.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0032418 lysosome localization(GO:0032418)
0.0 0.3 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.4 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.7 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0090279 regulation of calcium ion import(GO:0090279)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0043330 response to exogenous dsRNA(GO:0043330)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 4.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.7 GO:0005869 dynactin complex(GO:0005869)
0.1 0.2 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.0 1.1 GO:0046930 pore complex(GO:0046930)
0.0 1.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 1.2 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 3.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0072380 TRC complex(GO:0072380)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0035060 brahma complex(GO:0035060)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.4 1.4 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.4 1.1 GO:0048030 disaccharide binding(GO:0048030)
0.3 0.8 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 4.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.5 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 4.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0031704 apelin receptor binding(GO:0031704)
0.1 1.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.6 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 0.2 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.1 0.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 1.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.6 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.4 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0016496 substance P receptor activity(GO:0016496)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 3.6 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.1 GO:0019809 spermidine binding(GO:0019809)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.4 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882) structural constituent of synapse(GO:0098918)
0.0 0.0 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins