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PRJEB1986: zebrafish developmental stages transcriptome

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Results for mef2aa+mef2ab

Z-value: 2.16

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Transcription factors associated with mef2aa+mef2ab

Gene Symbol Gene ID Gene Info
mef2aa
ENSDARG00000031756 myocyte enhancer factor 2aa
mef2ab
ENSDARG00000057527 myocyte enhancer factor 2ab
mef2ab
ENSDARG00000110771 myocyte enhancer factor 2ab

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2aadr11_v1_chr18_+_23249519_232495190.931.2e-08Click!
mef2abdr11_v1_chr7_+_15659280_156592800.541.6e-02Click!

Activity profile of mef2aa+mef2ab motif

Sorted Z-values of mef2aa+mef2ab motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_61205711 15.47 ENSDART00000055062
pvalb1
parvalbumin 1
chr9_-_22205682 12.57 ENSDART00000101869
crygm2d12
crystallin, gamma M2d12
chr8_-_11112058 12.09 ENSDART00000042755
ampd1
adenosine monophosphate deaminase 1 (isoform M)
chr9_-_22188117 9.68 ENSDART00000132890
crygm2d17
crystallin, gamma M2d17
chr5_+_45677781 9.28 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr5_+_51597677 9.16 ENSDART00000048210
ENSDART00000184797
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr12_-_4781801 8.61 ENSDART00000167490
ENSDART00000121718
mapta
microtubule-associated protein tau a
chr8_+_34731982 7.68 ENSDART00000066050
hpdb
4-hydroxyphenylpyruvate dioxygenase b
chr7_-_27686021 6.76 ENSDART00000079112
ENSDART00000100989
calca
calcitonin/calcitonin-related polypeptide, alpha
chr3_+_32526263 6.38 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr25_+_19105804 6.04 ENSDART00000104414
rlbp1b
retinaldehyde binding protein 1b
chr12_-_17712393 6.02 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr16_-_36798783 5.91 ENSDART00000145697
calb1
calbindin 1
chr3_+_59051503 5.87 ENSDART00000160767
rasd4
rasd family member 4
chr4_-_16853464 5.87 ENSDART00000125743
ENSDART00000164570
slc25a3a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a
chr15_+_19652807 5.66 ENSDART00000134321
ENSDART00000054426
lim2.3
lens intrinsic membrane protein 2.3
chr12_-_4028079 5.52 ENSDART00000128676
si:ch211-180a12.2
si:ch211-180a12.2
chr8_+_22930627 5.27 ENSDART00000187860
sypa
synaptophysin a
chr5_+_36932718 5.21 ENSDART00000037879
crx
cone-rod homeobox
chr4_+_9279784 5.11 ENSDART00000014897
srgap1b
SLIT-ROBO Rho GTPase activating protein 1b
chr10_-_22845485 4.96 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr3_+_40170216 4.86 ENSDART00000011568
syngr3a
synaptogyrin 3a
chr6_-_13891727 4.77 ENSDART00000065356
desmb
desmin b
chr1_+_8601935 4.76 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr13_-_2215213 4.65 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr2_-_5356686 4.40 ENSDART00000124290
MFN1
mitofusin 1
chr3_-_32170850 4.30 ENSDART00000055307
ENSDART00000157366
tnnt1
troponin T type 1 (skeletal, slow)
chr18_+_45792035 4.16 ENSDART00000135045
abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr3_-_52614747 4.08 ENSDART00000154365
trim35-13
tripartite motif containing 35-13
chr20_-_47732703 4.07 ENSDART00000193975
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr5_-_57635664 3.95 ENSDART00000074306
hspb2
heat shock protein, alpha-crystallin-related, b2
chr21_-_32487061 3.91 ENSDART00000114359
ENSDART00000131591
ENSDART00000131477
si:dkeyp-72g9.4
si:dkeyp-72g9.4
chr16_+_5774977 3.89 ENSDART00000134202
ccka
cholecystokinin a
chr18_-_38087875 3.81 ENSDART00000111301
luzp2
leucine zipper protein 2
chr5_-_72125551 3.81 ENSDART00000149412
smyd1a
SET and MYND domain containing 1a
chr2_-_3678029 3.80 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr10_+_23511816 3.78 ENSDART00000127255
zmp:0000000924
zmp:0000000924
chr6_-_38816500 3.77 ENSDART00000190866
ENSDART00000104124
cnga3a
cyclic nucleotide gated channel alpha 3a
chr1_+_33969015 3.74 ENSDART00000042984
ENSDART00000146530
epha6
eph receptor A6
chr14_-_27297123 3.68 ENSDART00000173423
pcdh11
protocadherin 11
chr12_-_26064105 3.60 ENSDART00000168825
ldb3b
LIM domain binding 3b
chr1_+_7546259 3.56 ENSDART00000015732
mylz3
myosin, light polypeptide 3, skeletal muscle
chr21_+_12010505 3.56 ENSDART00000123522
aqp7
aquaporin 7
chr21_-_131236 3.54 ENSDART00000160005
si:ch1073-398f15.1
si:ch1073-398f15.1
chr18_+_23193820 3.48 ENSDART00000148106
mef2aa
myocyte enhancer factor 2aa
chr5_+_64732270 3.48 ENSDART00000134241
olfm1a
olfactomedin 1a
chr14_+_32837914 3.44 ENSDART00000158888
arr3b
arrestin 3b, retinal (X-arrestin)
chr20_-_26001288 3.44 ENSDART00000136518
ENSDART00000063177
capn3b
calpain 3b
chr17_-_16069905 3.40 ENSDART00000110383
map7a
microtubule-associated protein 7a
chr23_+_6077503 3.40 ENSDART00000081714
ENSDART00000139834
mybpha
myosin binding protein Ha
chr21_+_11685009 3.37 ENSDART00000014668
pcsk1
proprotein convertase subtilisin/kexin type 1
chr17_+_8184649 3.35 ENSDART00000091818
tulp4b
tubby like protein 4b
chr12_-_26064480 3.32 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
ldb3b
LIM domain binding 3b
chr21_+_11684830 3.30 ENSDART00000147473
pcsk1
proprotein convertase subtilisin/kexin type 1
chr5_-_20678300 3.30 ENSDART00000088639
wscd2
WSC domain containing 2
chr25_+_31264155 3.29 ENSDART00000012256
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr4_+_9279515 3.29 ENSDART00000048707
srgap1b
SLIT-ROBO Rho GTPase activating protein 1b
chr11_-_33960318 3.22 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr3_-_49504023 3.21 ENSDART00000168108
prkacaa
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr6_-_49873020 3.21 ENSDART00000148511
gnas
GNAS complex locus
chr17_-_12336987 3.20 ENSDART00000172001
snap25b
synaptosomal-associated protein, 25b
chr7_-_7420301 3.17 ENSDART00000102620
six7
SIX homeobox 7
chr19_-_7450796 3.13 ENSDART00000104750
mllt11
MLLT11, transcription factor 7 cofactor
chr16_-_32975951 3.11 ENSDART00000101969
ENSDART00000175149
me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr19_+_15571290 3.09 ENSDART00000131134
foxo6b
forkhead box O6 b
chr3_+_31953145 3.02 ENSDART00000148861
kcnc3a
potassium voltage-gated channel, Shaw-related subfamily, member 3a
chr23_+_14097508 2.90 ENSDART00000087280
cacnb3a
calcium channel, voltage-dependent, beta 3a
chr18_+_7264961 2.89 ENSDART00000188461
CABZ01015105.1

chr13_+_25853757 2.88 ENSDART00000132521
bcl11aa
B cell CLL/lymphoma 11Aa
chr10_+_41765616 2.87 ENSDART00000170682
rnf34b
ring finger protein 34b
chr10_-_23358357 2.85 ENSDART00000135475
cadm2a
cell adhesion molecule 2a
chr18_+_10820430 2.84 ENSDART00000161990
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr10_+_32561317 2.83 ENSDART00000109029
map6a
microtubule-associated protein 6a
chr6_+_41038757 2.83 ENSDART00000011245
entpd8
ectonucleoside triphosphate diphosphohydrolase 8
chr17_+_28340138 2.81 ENSDART00000033943
mdga2a
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr9_-_52814204 2.81 ENSDART00000140771
ENSDART00000007401
MAP3K13
si:ch211-45c16.2
chr18_+_23193567 2.80 ENSDART00000190072
ENSDART00000171594
ENSDART00000181762
mef2aa
myocyte enhancer factor 2aa
chr15_-_14375452 2.79 ENSDART00000160675
ENSDART00000164028
ENSDART00000171642
dpf1
D4, zinc and double PHD fingers family 1
chr23_+_17981127 2.78 ENSDART00000012571
ENSDART00000145200
chia.6
chitinase, acidic.6
chr23_-_27633730 2.77 ENSDART00000103639
arf3a
ADP-ribosylation factor 3a
chr9_-_23990416 2.77 ENSDART00000113176
col6a3
collagen, type VI, alpha 3
chr10_+_21776911 2.77 ENSDART00000163077
ENSDART00000186093
pcdh1g22
protocadherin 1 gamma 22
chr6_+_12462079 2.77 ENSDART00000192029
ENSDART00000065385
nr4a2b
nuclear receptor subfamily 4, group A, member 2b
chr10_-_24371312 2.76 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr2_+_37110504 2.76 ENSDART00000132794
ENSDART00000042974
slc1a8b
solute carrier family 1 (glutamate transporter), member 8b
chr24_+_34089977 2.75 ENSDART00000157466
asb10
ankyrin repeat and SOCS box containing 10
chr16_-_43356018 2.75 ENSDART00000181683
FO704821.1

chr2_+_48074243 2.72 ENSDART00000056291
klf6b
Kruppel-like factor 6b
chr7_-_66864756 2.72 ENSDART00000184462
ENSDART00000189424
ampd3a
adenosine monophosphate deaminase 3a
chr19_-_12648122 2.72 ENSDART00000151184
fam210aa
family with sequence similarity 210, member Aa
chr17_-_39886628 2.71 ENSDART00000002217
zmp:0000000545
zmp:0000000545
chr20_+_16881883 2.71 ENSDART00000130107
nfkbiaa
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr7_+_7048245 2.71 ENSDART00000001649
actn3b
actinin alpha 3b
chr9_-_42873700 2.69 ENSDART00000125953
ttn.1
titin, tandem duplicate 1
chr16_+_25245857 2.68 ENSDART00000155220
klhl38b
kelch-like family member 38b
chr1_-_8917902 2.60 ENSDART00000137900
grin2ab
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr25_-_23745765 2.58 ENSDART00000089278
si:ch211-236l14.4
si:ch211-236l14.4
chr25_+_14087045 2.57 ENSDART00000155770
actc1c
actin, alpha, cardiac muscle 1c
chr20_+_34455645 2.57 ENSDART00000135789
mettl11b
methyltransferase like 11B
chr21_-_22910520 2.57 ENSDART00000065567
ENSDART00000191792
guca1d
guanylate cyclase activator 1d
chr11_-_19650781 2.56 ENSDART00000165595
SYNPR
si:dkey-30j16.3
chr25_+_20077225 2.55 ENSDART00000136543
tnni4b.1
troponin I4b, tandem duplicate 1
chrM_-_15232 2.52 ENSDART00000093623
mt-nd6
NADH dehydrogenase 6, mitochondrial
chr3_-_42981739 2.52 ENSDART00000167844
mafk
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr23_-_19953089 2.49 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr23_+_36601984 2.41 ENSDART00000128598
igfbp6b
insulin-like growth factor binding protein 6b
chr15_-_22139566 2.38 ENSDART00000149017
scn3b
sodium channel, voltage-gated, type III, beta
chr14_-_46451249 2.37 ENSDART00000058466
fgfbp2a
fibroblast growth factor binding protein 2a
chr19_-_10394931 2.35 ENSDART00000191549
zgc:194578
zgc:194578
chr16_-_19890303 2.34 ENSDART00000147161
ENSDART00000079159
hdac9b
histone deacetylase 9b
chr17_-_50233493 2.32 ENSDART00000172266
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr2_+_48073972 2.32 ENSDART00000186442
klf6b
Kruppel-like factor 6b
chr5_-_64511428 2.29 ENSDART00000016321
rxrab
retinoid x receptor, alpha b
chr8_+_52637507 2.29 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr3_+_28953274 2.27 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr17_-_50234004 2.26 ENSDART00000058706
fosaa
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr1_-_22652424 2.22 ENSDART00000036797
uchl1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr18_-_6832337 2.20 ENSDART00000139360
ppp6r2b
protein phosphatase 6, regulatory subunit 2b
chr1_+_19708508 2.15 ENSDART00000054581
ENSDART00000131206
march1
membrane-associated ring finger (C3HC4) 1
chr25_+_3677650 2.14 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr8_-_32497815 2.12 ENSDART00000122359
si:dkey-164f24.2
si:dkey-164f24.2
chr14_-_2318590 2.06 ENSDART00000192735
pcdh2ab8
protocadherin 2 alpha b 8
chr15_+_28940352 2.03 ENSDART00000154085
gipr
gastric inhibitory polypeptide receptor
chr25_-_28384954 2.03 ENSDART00000073500
ptprz1a
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr11_+_11200550 2.02 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr9_+_29643036 2.02 ENSDART00000023210
ENSDART00000175160
trim13
tripartite motif containing 13
chr9_-_23891102 2.02 ENSDART00000186799
asb18
ankyrin repeat and SOCS box containing 18
chr12_-_6905375 2.00 ENSDART00000152322
pcdh15b
protocadherin-related 15b
chr13_+_22480857 1.99 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
ldb3a
LIM domain binding 3a
chr7_+_6969909 1.94 ENSDART00000189886
actn3b
actinin alpha 3b
chr20_+_33532296 1.91 ENSDART00000153153
kcnf1a
potassium voltage-gated channel, subfamily F, member 1a
chr8_-_12264486 1.89 ENSDART00000091612
ENSDART00000135812
dab2ipa
DAB2 interacting protein a
chr1_+_38858399 1.88 ENSDART00000165454
CU915762.1

chr9_-_43073960 1.87 ENSDART00000059460
ttn.2
titin, tandem duplicate 2
chr2_-_8611675 1.86 ENSDART00000138223
si:ch211-71m22.1
si:ch211-71m22.1
chr17_-_43558494 1.86 ENSDART00000103830
nt5c1ab
5'-nucleotidase, cytosolic IAb
chr19_-_31035155 1.85 ENSDART00000161882
bzw2
basic leucine zipper and W2 domains 2
chr6_+_57541776 1.83 ENSDART00000157330
necab3
N-terminal EF-hand calcium binding protein 3
chr7_+_72882446 1.83 ENSDART00000131113
ENSDART00000174223
ADGRL3
adhesion G protein-coupled receptor L3
chr19_-_31035325 1.82 ENSDART00000147504
bzw2
basic leucine zipper and W2 domains 2
chr23_+_17980875 1.78 ENSDART00000163452
chia.6
chitinase, acidic.6
chr3_+_32403758 1.78 ENSDART00000156982
si:ch211-195b15.8
si:ch211-195b15.8
chr5_+_69808763 1.77 ENSDART00000143482
fsd1l
fibronectin type III and SPRY domain containing 1-like
chr2_-_36925561 1.76 ENSDART00000187690
map1sb
microtubule-associated protein 1Sb
chr20_-_2134620 1.76 ENSDART00000064375
tmem244
transmembrane protein 244
chr16_-_16590489 1.71 ENSDART00000190021
si:ch211-257p13.3
si:ch211-257p13.3
chr7_-_42206720 1.70 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr21_-_40083432 1.69 ENSDART00000141160
ENSDART00000191195
slc13a5a
info solute carrier family 13 (sodium-dependent citrate transporter), member 5a
chr14_-_7245971 1.66 ENSDART00000108796
stox2b
storkhead box 2b
chr16_+_29663809 1.65 ENSDART00000191336
tmod4
tropomodulin 4 (muscle)
chr7_+_69841017 1.62 ENSDART00000169107
FO818704.1

chr6_-_12459412 1.58 ENSDART00000090266
ENSDART00000144028
gpd2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr23_+_20110086 1.58 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr20_+_6756247 1.56 ENSDART00000167344
igfbp3
insulin-like growth factor binding protein 3
chr13_+_31172833 1.55 ENSDART00000176378
CR931802.3

chr16_+_20161805 1.54 ENSDART00000192146
c16h2orf66
chromosome 16 C2orf66 homolog
chr10_-_10607118 1.48 ENSDART00000101089
dbh
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr24_-_6647275 1.47 ENSDART00000161494
arhgap21a
Rho GTPase activating protein 21a
chr17_-_5583345 1.46 ENSDART00000035944
clic5a
chloride intracellular channel 5a
chr1_-_37383741 1.45 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr17_+_43623598 1.42 ENSDART00000154138
znf365
zinc finger protein 365
chr11_-_26701611 1.41 ENSDART00000083010
acad9
acyl-CoA dehydrogenase family, member 9
chr16_+_32029090 1.40 ENSDART00000041054
tmc4
transmembrane channel-like 4
chr12_-_15584479 1.40 ENSDART00000150134
acbd4
acyl-CoA binding domain containing 4
chr21_+_43559123 1.40 ENSDART00000151212
gpr185a
G protein-coupled receptor 185 a
chr2_-_15324837 1.39 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr11_-_40030139 1.39 ENSDART00000021916
uts2b
urotensin 2, beta
chr22_-_13649588 1.38 ENSDART00000131877
si:ch211-279g13.1
si:ch211-279g13.1
chr5_+_19094153 1.36 ENSDART00000186525
ENSDART00000064752
unc13ba
unc-13 homolog Ba (C. elegans)
chr22_+_38301365 1.35 ENSDART00000137339
traf5
Tnf receptor-associated factor 5
chr12_+_8003872 1.34 ENSDART00000180300
ENSDART00000126661
rhobtb1
Rho-related BTB domain containing 1
chr21_-_5799122 1.34 ENSDART00000129351
ENSDART00000151202
ccni
cyclin I
chr18_+_39327010 1.33 ENSDART00000012164
tmod2
tropomodulin 2
chr8_+_30456161 1.32 ENSDART00000085894
pgm5
phosphoglucomutase 5
chr1_-_11075403 1.31 ENSDART00000102903
ENSDART00000170290
dmd
dystrophin
chr7_+_42206847 1.28 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr10_-_41450367 1.27 ENSDART00000122682
ENSDART00000189549
cabp1b
calcium binding protein 1b
chr6_-_19351495 1.26 ENSDART00000164287
grb2a
growth factor receptor-bound protein 2a
chr21_+_40944530 1.26 ENSDART00000022976
kctd16b
potassium channel tetramerization domain containing 16b
chr19_+_24394560 1.23 ENSDART00000142506
si:dkey-81h8.1
si:dkey-81h8.1
chr19_+_2590182 1.22 ENSDART00000162293
si:ch73-345f18.3
si:ch73-345f18.3
chr16_-_17541890 1.20 ENSDART00000131328
clcn1b
chloride channel, voltage-sensitive 1b
chr7_+_39006837 1.19 ENSDART00000173735
dgkza
diacylglycerol kinase, zeta a
chr8_-_32497581 1.19 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
si:dkey-164f24.2
chr7_+_40093662 1.19 ENSDART00000053011
si:ch73-174h16.4
si:ch73-174h16.4
chr2_+_8779164 1.19 ENSDART00000134308
zzz3
zinc finger, ZZ-type containing 3
chr7_-_31321027 1.18 ENSDART00000186878
CR356242.1

chr8_-_42594380 1.15 ENSDART00000140126
ENSDART00000135238
ENSDART00000192764
dok2
docking protein 2
chr3_+_32933663 1.15 ENSDART00000112742
nbr1b
neighbor of brca1 gene 1b
chr17_-_28770800 1.11 ENSDART00000156485
opn6b
opsin 6, group member b
chr25_+_10793478 1.11 ENSDART00000058339
ENSDART00000134923
ap3s2
adaptor-related protein complex 3, sigma 2 subunit
chr8_-_42238543 1.10 ENSDART00000062697
gfra2a
GDNF family receptor alpha 2a
chr5_+_19094462 1.09 ENSDART00000190596
unc13ba
unc-13 homolog Ba (C. elegans)
chr24_+_38155830 1.08 ENSDART00000152019
si:ch211-234p6.5
si:ch211-234p6.5
chr14_+_11430796 1.07 ENSDART00000165275
si:ch211-153b23.3
si:ch211-153b23.3
chr14_+_23811808 1.03 ENSDART00000014411
kctd16a
potassium channel tetramerization domain containing 16a
chr14_+_30910114 1.01 ENSDART00000187166
ENSDART00000078187
foxo4
forkhead box O4
chr8_-_4972916 1.00 ENSDART00000101576
tmem230b
transmembrane protein 230b
chr24_+_20960216 1.00 ENSDART00000133008
si:ch211-161h7.8
si:ch211-161h7.8
chr6_-_37468971 0.99 ENSDART00000126379
plcxd1
phosphatidylinositol-specific phospholipase C, X domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2aa+mef2ab

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
1.3 7.7 GO:0006572 tyrosine catabolic process(GO:0006572)
1.1 3.4 GO:0097264 self proteolysis(GO:0097264)
1.1 15.0 GO:0032264 IMP salvage(GO:0032264)
1.0 5.0 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.9 2.7 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.8 4.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.7 2.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.7 9.2 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.6 3.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.6 4.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.6 2.4 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.5 2.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.5 1.5 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.5 1.0 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.4 6.7 GO:0016486 peptide hormone processing(GO:0016486)
0.4 3.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.4 4.6 GO:0006032 chitin catabolic process(GO:0006032)
0.4 4.6 GO:0048769 sarcomerogenesis(GO:0048769)
0.4 1.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.4 2.9 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.4 2.4 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.4 3.5 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.4 3.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 4.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.4 3.2 GO:0071331 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.3 5.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.3 9.3 GO:0051180 vitamin transport(GO:0051180)
0.3 4.8 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.3 3.1 GO:0006108 malate metabolic process(GO:0006108)
0.3 2.8 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.3 3.4 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.3 5.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 1.8 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 4.5 GO:0007634 optokinetic behavior(GO:0007634)
0.2 2.4 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 1.9 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.2 3.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 6.8 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 3.2 GO:0046549 retinal cone cell development(GO:0046549)
0.2 2.3 GO:0090303 positive regulation of wound healing(GO:0090303)
0.2 0.9 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 7.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 1.7 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 0.8 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.2 2.8 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.2 0.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 1.0 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.1 32.3 GO:0007601 visual perception(GO:0007601)
0.1 1.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 2.6 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 1.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.7 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 8.4 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 1.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 3.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 3.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 3.9 GO:0007586 digestion(GO:0007586)
0.1 2.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 2.3 GO:0032526 response to retinoic acid(GO:0032526)
0.1 1.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.6 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 1.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.4 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 0.4 GO:0021634 optic nerve formation(GO:0021634)
0.1 0.7 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.5 GO:0002931 response to ischemia(GO:0002931)
0.1 1.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 5.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 2.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 8.5 GO:0001756 somitogenesis(GO:0001756)
0.1 1.4 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 5.9 GO:0031101 fin regeneration(GO:0031101)
0.1 0.2 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 1.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 1.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 5.5 GO:0006936 muscle contraction(GO:0006936)
0.0 0.7 GO:0060841 venous blood vessel development(GO:0060841)
0.0 2.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 2.8 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 1.0 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 4.2 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.3 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.3 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 2.3 GO:0006006 glucose metabolic process(GO:0006006)
0.0 2.8 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 2.5 GO:0010506 regulation of autophagy(GO:0010506)
0.0 1.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.4 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.8 GO:0006821 chloride transport(GO:0006821)
0.0 0.6 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.5 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.6 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.7 GO:0048599 oocyte development(GO:0048599)
0.0 0.6 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 0.6 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.2 GO:0016236 macroautophagy(GO:0016236)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 2.1 GO:0033674 positive regulation of kinase activity(GO:0033674)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 8.4 GO:0043195 terminal bouton(GO:0043195)
0.3 3.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 5.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 5.8 GO:0031430 M band(GO:0031430)
0.3 11.7 GO:0005861 troponin complex(GO:0005861)
0.2 0.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 5.1 GO:0031594 neuromuscular junction(GO:0031594)
0.2 3.0 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.2 8.9 GO:0031941 filamentous actin(GO:0031941)
0.2 2.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 3.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 2.8 GO:0005801 cis-Golgi network(GO:0005801)
0.1 5.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 4.7 GO:0016605 PML body(GO:0016605)
0.1 2.8 GO:0071565 nBAF complex(GO:0071565)
0.1 1.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 5.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 2.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 2.0 GO:0032420 stereocilium(GO:0032420)
0.1 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.1 5.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.6 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 1.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 3.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 4.9 GO:0005882 intermediate filament(GO:0005882)
0.0 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 3.6 GO:0005581 collagen trimer(GO:0005581)
0.0 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.0 GO:0070469 respiratory chain(GO:0070469)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.3 GO:0042383 sarcolemma(GO:0042383)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 9.6 GO:0005874 microtubule(GO:0005874)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 4.4 GO:0030424 axon(GO:0030424)
0.0 1.9 GO:0005769 early endosome(GO:0005769)
0.0 1.9 GO:0000786 nucleosome(GO:0000786)
0.0 2.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 17.0 GO:0005739 mitochondrion(GO:0005739)
0.0 5.3 GO:0043235 receptor complex(GO:0043235)
0.0 2.7 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.2 GO:0005499 vitamin D binding(GO:0005499)
2.6 7.7 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
2.3 6.8 GO:0031716 calcitonin receptor binding(GO:0031716)
1.4 15.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.2 4.7 GO:0005521 lamin binding(GO:0005521)
0.8 3.1 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.7 9.2 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.6 3.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.6 3.2 GO:0031852 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.6 4.8 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.5 1.5 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.5 1.4 GO:0030882 lipid antigen binding(GO:0030882)
0.5 1.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.4 8.9 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.4 3.6 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.4 1.7 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.4 4.6 GO:0004568 chitinase activity(GO:0004568)
0.4 2.0 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.4 15.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.4 2.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 4.0 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.3 27.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 7.3 GO:0005523 tropomyosin binding(GO:0005523)
0.3 2.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3 5.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 2.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.3 3.8 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.3 2.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 2.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 0.7 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 3.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2 3.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.8 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 0.7 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.2 2.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 2.8 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 1.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.9 GO:0008126 acetylesterase activity(GO:0008126)
0.1 1.0 GO:0034632 retinol transporter activity(GO:0034632)
0.1 3.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.3 GO:0016936 galactoside binding(GO:0016936)
0.1 2.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 6.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 3.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 3.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 3.1 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 3.3 GO:0019003 GDP binding(GO:0019003)
0.1 0.3 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 1.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 1.0 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 2.1 GO:0042287 MHC protein binding(GO:0042287)
0.1 6.0 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.1 1.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 2.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.0 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 1.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.9 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 1.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 13.6 GO:0008017 microtubule binding(GO:0008017)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 2.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 23.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.3 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 1.4 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.1 GO:0000049 tRNA binding(GO:0000049)
0.0 1.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 3.0 GO:0043492 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 1.2 GO:0030276 clathrin binding(GO:0030276)
0.0 1.5 GO:0005254 chloride channel activity(GO:0005254)
0.0 3.2 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 6.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.8 GO:0015293 symporter activity(GO:0015293)
0.0 2.9 GO:0042393 histone binding(GO:0042393)
0.0 5.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 1.0 GO:0019838 growth factor binding(GO:0019838)
0.0 1.3 GO:0005516 calmodulin binding(GO:0005516)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 6.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 2.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
1.2 12.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
1.2 3.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.7 6.7 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.4 0.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 9.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.3 4.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.3 6.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 6.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 5.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 1.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 1.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 6.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 6.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 2.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.6 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA