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PRJEB1986: zebrafish developmental stages transcriptome

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Results for meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

Z-value: 0.57

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Transcription factors associated with meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

Gene Symbol Gene ID Gene Info
meis2b
ENSDARG00000077840 Meis homeobox 2a
meis2a
ENSDARG00000098240 Meis homeobox 2a
FO834857.1
ENSDARG00000112895 homeobox protein TGIF2-like
pknox1.1
ENSDARG00000018765 pbx/knotted 1 homeobox 1.1
pknox1.2
ENSDARG00000036542 pbx/knotted 1 homeobox 1.2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meis2adr11_v1_chr17_+_52823015_528231380.862.4e-06Click!
pknox1.2dr11_v1_chr1_-_46981134_469811340.652.6e-03Click!
pknox1.1dr11_v1_chr9_+_19529951_19529951-0.483.9e-02Click!
meis2bdr11_v1_chr20_-_10120442_101204420.223.7e-01Click!
FO834857.1dr11_v1_chr6_-_1814457_18144570.184.6e-01Click!

Activity profile of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2 motif

Sorted Z-values of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22213297 4.47 ENSDART00000110656
ENSDART00000133149
crygm2d20
crystallin, gamma M2d20
chr10_+_26800213 3.58 ENSDART00000078996
arr3a
arrestin 3a, retinal (X-arrestin)
chr7_+_10592152 3.19 ENSDART00000182624
fah
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr13_-_7031033 2.83 ENSDART00000193211
CABZ01061524.1

chr15_+_19652807 2.33 ENSDART00000134321
ENSDART00000054426
lim2.3
lens intrinsic membrane protein 2.3
chr1_-_22691182 2.03 ENSDART00000076766
fgfbp2b
fibroblast growth factor binding protein 2b
chr11_-_32723851 1.95 ENSDART00000155592
pcdh17
protocadherin 17
chr11_+_25459697 1.86 ENSDART00000161481
opn1sw2
opsin 1 (cone pigments), short-wave-sensitive 2
chr20_+_28434196 1.76 ENSDART00000034245
dpf3
D4, zinc and double PHD fingers, family 3
chr8_+_34731982 1.62 ENSDART00000066050
hpdb
4-hydroxyphenylpyruvate dioxygenase b
chr14_+_46410766 1.46 ENSDART00000032342
anxa5a
annexin A5a
chr11_+_40649412 1.36 ENSDART00000043016
ENSDART00000134560
slc45a1
solute carrier family 45, member 1
chr5_-_71722257 1.30 ENSDART00000013404
ak1
adenylate kinase 1
chr20_-_47731768 1.27 ENSDART00000031167
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr1_-_14234076 1.25 ENSDART00000040049
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr1_-_14233815 1.25 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr3_-_28428198 1.22 ENSDART00000151546
rbfox1
RNA binding fox-1 homolog 1
chr11_+_1796426 1.20 ENSDART00000173330
lrp1aa
low density lipoprotein receptor-related protein 1Aa
chr8_-_33114202 1.17 ENSDART00000098840
ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr8_+_25351863 1.13 ENSDART00000034092
dnase1l1l
deoxyribonuclease I-like 1-like
chr4_+_7841627 1.09 ENSDART00000037997
ucmaa
upper zone of growth plate and cartilage matrix associated a
chr19_-_6134802 1.08 ENSDART00000140051
cica
capicua transcriptional repressor a
chr7_-_58269812 1.03 ENSDART00000050077
sdcbp
syndecan binding protein (syntenin)
chr3_-_36612877 0.98 ENSDART00000167164
si:dkeyp-72e1.7
si:dkeyp-72e1.7
chr5_+_32246872 0.95 ENSDART00000139917
myha
myosin, heavy chain a
chr16_-_563235 0.94 ENSDART00000016303
irx2a
iroquois homeobox 2a
chr22_-_16377666 0.93 ENSDART00000161878
ttc39c
tetratricopeptide repeat domain 39C
chr18_+_907266 0.93 ENSDART00000171729
pkma
pyruvate kinase M1/2a
chr12_-_22039350 0.91 ENSDART00000153187
thrab
thyroid hormone receptor alpha b
chr6_+_27151940 0.88 ENSDART00000088364
kif1aa
kinesin family member 1Aa
chr12_+_46960579 0.87 ENSDART00000149032
oat
ornithine aminotransferase
chr20_-_27733683 0.85 ENSDART00000103317
ENSDART00000138139
zgc:153157
zgc:153157
chr23_+_5465806 0.85 ENSDART00000149434
ENSDART00000148506
tulp1a
tubby like protein 1a
chr1_-_44084071 0.83 ENSDART00000166912
vwa11
von Willebrand factor A domain containing 11
chr13_+_45524475 0.82 ENSDART00000074567
ENSDART00000019113
maco1b
macoilin 1b
chr3_+_13190012 0.82 ENSDART00000179747
ENSDART00000109876
ENSDART00000124824
ENSDART00000130261
sun1
Sad1 and UNC84 domain containing 1
chr7_+_14291323 0.82 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr5_+_27137473 0.81 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr6_+_38381957 0.81 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr13_+_46803979 0.81 ENSDART00000159260
CU695232.1

chr20_-_43771871 0.80 ENSDART00000153304
matn3a
matrilin 3a
chr7_-_38340674 0.80 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr25_+_3326885 0.79 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr16_-_563732 0.73 ENSDART00000183394
irx2a
iroquois homeobox 2a
chr3_+_35298078 0.73 ENSDART00000110126
cacng3b
calcium channel, voltage-dependent, gamma subunit 3b
chr24_-_12981423 0.72 ENSDART00000133166
ENSDART00000131370
ENSDART00000002992
dcaf11
ddb1 and cul4 associated factor 11
chr3_-_27880229 0.72 ENSDART00000151404
abat
4-aminobutyrate aminotransferase
chr21_+_45733871 0.72 ENSDART00000187285
ENSDART00000193018
zgc:77058
zgc:77058
chr10_-_42131408 0.71 ENSDART00000076693
stambpa
STAM binding protein a
chr18_+_39487486 0.71 ENSDART00000126978
acadl
acyl-CoA dehydrogenase long chain
chr1_+_14253118 0.70 ENSDART00000161996
cxcl8a
chemokine (C-X-C motif) ligand 8a
chr6_-_57539141 0.70 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr1_+_50997156 0.69 ENSDART00000010449
ugp2a
UDP-glucose pyrophosphorylase 2a
chr23_-_7826849 0.68 ENSDART00000157612
myt1b
myelin transcription factor 1b
chr8_+_23703680 0.67 ENSDART00000141099
ENSDART00000135394
ppardb
peroxisome proliferator-activated receptor delta b
chr25_-_21894317 0.66 ENSDART00000089642
fbxo31
F-box protein 31
chr2_-_39090258 0.66 ENSDART00000134270
ENSDART00000145268
NMNAT3
si:ch73-170l17.1
chr24_+_42148140 0.66 ENSDART00000010658
serpinb1l3
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr21_-_41025340 0.65 ENSDART00000148231
plac8l1
PLAC8-like 1
chr6_-_40697585 0.65 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr19_+_10396042 0.64 ENSDART00000028048
ENSDART00000151735
necap1
NECAP endocytosis associated 1
chr8_-_50525360 0.63 ENSDART00000175648
CABZ01060030.1

chr24_-_37568359 0.63 ENSDART00000056286
h1f0
H1 histone family, member 0
chr21_+_39336285 0.63 ENSDART00000139677
si:ch211-274p24.4
si:ch211-274p24.4
chr16_+_50434668 0.62 ENSDART00000193500
IGLON5
zgc:110372
chr13_+_36764715 0.62 ENSDART00000111832
ENSDART00000085230
atl1
atlastin GTPase 1
chr19_-_10395683 0.61 ENSDART00000109488
zgc:194578
zgc:194578
chr11_+_38280454 0.60 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr9_-_48397702 0.60 ENSDART00000147169
zgc:172182
zgc:172182
chr11_+_44356504 0.59 ENSDART00000160678
srsf7b
serine/arginine-rich splicing factor 7b
chr7_-_71829649 0.58 ENSDART00000160449
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr13_+_7292061 0.58 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr23_-_18024543 0.58 ENSDART00000139695
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr5_-_13766651 0.57 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr4_-_15603511 0.56 ENSDART00000122520
ENSDART00000162356
chchd3a
coiled-coil-helix-coiled-coil-helix domain containing 3a
chr14_-_32255126 0.56 ENSDART00000017259
fgf13a
fibroblast growth factor 13a
chr5_-_69482891 0.55 ENSDART00000109487
CABZ01032476.1

chr6_+_48041759 0.54 ENSDART00000140086
si:dkey-92f12.2
si:dkey-92f12.2
chr23_+_19558574 0.54 ENSDART00000137811
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr21_-_16399778 0.53 ENSDART00000136435
unc5da
unc-5 netrin receptor Da
chr25_+_3327071 0.52 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr9_-_12575776 0.52 ENSDART00000128931
ENSDART00000182695
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr3_+_22273123 0.52 ENSDART00000044157
scn4ab
sodium channel, voltage-gated, type IV, alpha, b
chr21_+_38312549 0.52 ENSDART00000065159
zgc:158291
zgc:158291
chr22_-_14128716 0.51 ENSDART00000140323
si:ch211-246m6.4
si:ch211-246m6.4
chr5_-_25406807 0.51 ENSDART00000089748
rorb
RAR-related orphan receptor B
chr8_-_410728 0.51 ENSDART00000151255
trim36
tripartite motif containing 36
chr7_-_38638276 0.49 ENSDART00000074463
c6ast4
six-cysteine containing astacin protease 4
chr8_+_23213320 0.49 ENSDART00000032996
ENSDART00000137536
ppdpfa
pancreatic progenitor cell differentiation and proliferation factor a
chr9_-_12575569 0.48 ENSDART00000102419
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr22_+_7480465 0.48 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr15_+_21862295 0.48 ENSDART00000154449
ENSDART00000180774
si:dkey-103g5.3
si:dkey-103g5.3
chr11_-_41132296 0.47 ENSDART00000162944
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr12_+_17504559 0.47 ENSDART00000020628
cyth3a
cytohesin 3a
chr4_+_27898833 0.47 ENSDART00000146099
cerk
ceramide kinase
chr23_+_39963599 0.46 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr2_+_52232630 0.46 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr16_-_16152199 0.46 ENSDART00000012718
fabp11b
fatty acid binding protein 11b
chr20_+_14968031 0.46 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vamp4
vesicle-associated membrane protein 4
chr16_+_12240605 0.45 ENSDART00000060056
tpi1b
triosephosphate isomerase 1b
chr19_+_46824723 0.45 ENSDART00000158620
AL953858.1

chr17_+_33999630 0.45 ENSDART00000167085
ENSDART00000155030
ENSDART00000168522
ENSDART00000191799
ENSDART00000189684
ENSDART00000153942
ENSDART00000187272
ENSDART00000127692
gphna
gephyrin a
chr15_-_34845414 0.45 ENSDART00000009892
gabbr1a
gamma-aminobutyric acid (GABA) B receptor, 1a
chr21_-_32684570 0.44 ENSDART00000162873
adamts2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr23_+_33963619 0.44 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr1_+_41666611 0.44 ENSDART00000145789
fbxo41
F-box protein 41
chr11_+_30513656 0.43 ENSDART00000008594
tmem178
transmembrane protein 178
chr24_-_36095526 0.43 ENSDART00000158145
CABZ01075509.1

chr21_+_1380099 0.43 ENSDART00000184516
TCF4
transcription factor 4
chr25_-_3549321 0.43 ENSDART00000181214
ENSDART00000160600
hdhd5
haloacid dehalogenase like hydrolase domain containing 5
chr8_-_17167819 0.42 ENSDART00000135042
ENSDART00000143920
mrps36
mitochondrial ribosomal protein S36
chr23_-_15216654 0.42 ENSDART00000131649
sulf2b
sulfatase 2b
chr24_+_3963684 0.42 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
pfkpa
phosphofructokinase, platelet a
chr12_-_43982343 0.42 ENSDART00000161539
CR385054.1

chr15_-_46718759 0.42 ENSDART00000085926
ENSDART00000154577
zgc:162872
zgc:162872
chr3_-_28258462 0.41 ENSDART00000191573
rbfox1
RNA binding fox-1 homolog 1
chr5_+_6796291 0.41 ENSDART00000166868
ENSDART00000165308
me2
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr5_-_18474486 0.41 ENSDART00000090580
si:dkey-215k6.1
si:dkey-215k6.1
chr23_+_21067684 0.41 ENSDART00000132066
kcnab2b
potassium voltage-gated channel, shaker-related subfamily, beta member 2 b
chr11_+_24001993 0.41 ENSDART00000168215
chia.2
chitinase, acidic.2
chr18_+_507835 0.40 ENSDART00000189701
nedd4a
neural precursor cell expressed, developmentally down-regulated 4a
chr3_-_32169754 0.39 ENSDART00000179010
tnnt1
troponin T type 1 (skeletal, slow)
chr2_-_51794472 0.39 ENSDART00000186652
BX908782.3

chr3_+_24986145 0.38 ENSDART00000055428
cbx7a
chromobox homolog 7a
chr23_-_36592436 0.38 ENSDART00000168246
spryd3
SPRY domain containing 3
chr23_-_29667544 0.37 ENSDART00000059339
clstn1
calsyntenin 1
chr20_-_25522911 0.37 ENSDART00000063058
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr22_+_19188809 0.37 ENSDART00000134791
ENSDART00000133682
si:dkey-21e2.8
si:dkey-21e2.8
chr2_+_39021282 0.37 ENSDART00000056577
RBP1 (1 of many)
si:ch211-119o8.7
chr21_-_43474012 0.36 ENSDART00000065104
tmem185
transmembrane protein 185
chr5_+_15992655 0.36 ENSDART00000182148
znrf3
zinc and ring finger 3
chr5_+_19320554 0.36 ENSDART00000165119
rusc2
RUN and SH3 domain containing 2
chr14_+_29200772 0.35 ENSDART00000166608
TENM2
si:dkey-34l15.2
chr11_+_6422374 0.35 ENSDART00000183148
FO681393.1

chr6_+_23931236 0.35 ENSDART00000166079
gadd45ab
growth arrest and DNA-damage-inducible, alpha, b
chr2_+_5620742 0.35 ENSDART00000028390
fgf12a
fibroblast growth factor 12a
chr22_-_21897203 0.35 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr16_+_11151699 0.35 ENSDART00000140674
cicb
capicua transcriptional repressor b
chr17_+_37624704 0.34 ENSDART00000157001
tmem229b
transmembrane protein 229B
chr4_+_22613625 0.34 ENSDART00000131161
sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_-_20669635 0.34 ENSDART00000131361
kcnip3b
Kv channel interacting protein 3b, calsenilin
chr10_-_7671219 0.34 ENSDART00000159330
pcyox1
prenylcysteine oxidase 1
chr18_-_7810214 0.34 ENSDART00000139505
ENSDART00000139188
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr22_+_1006573 0.33 ENSDART00000123458
pparda
peroxisome proliferator-activated receptor delta a
chr18_-_444168 0.33 ENSDART00000170389
wtip
WT1 interacting protein
chr2_+_9918935 0.33 ENSDART00000140434
acbd5b
acyl-CoA binding domain containing 5b
chr3_-_50146854 0.33 ENSDART00000157047
si:dkey-120c6.5
si:dkey-120c6.5
chr1_+_45217425 0.33 ENSDART00000179983
ENSDART00000074683
EVI5L
si:ch211-239f4.1
chr4_-_17629444 0.32 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr18_-_33344 0.32 ENSDART00000129125
pde8a
phosphodiesterase 8A
chr22_-_16377960 0.32 ENSDART00000168170
ttc39c
tetratricopeptide repeat domain 39C
chr13_+_27314795 0.32 ENSDART00000128726
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr18_-_8313686 0.32 ENSDART00000182187
mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr9_-_22821901 0.32 ENSDART00000101711
neb
nebulin
chr22_-_23253481 0.32 ENSDART00000054807
lhx9
LIM homeobox 9
chr2_+_9918678 0.31 ENSDART00000081253
acbd5b
acyl-CoA binding domain containing 5b
chr1_+_2301961 0.31 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr20_-_46467280 0.31 ENSDART00000060702
rmdn3
regulator of microtubule dynamics 3
chr7_-_68373495 0.31 ENSDART00000167440
zfhx3
zinc finger homeobox 3
chr4_-_5291256 0.31 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr5_-_323712 0.30 ENSDART00000188793
HOOK3
hook microtubule tethering protein 3
chr16_-_20492799 0.30 ENSDART00000014769
chn2
chimerin 2
chr12_+_32159272 0.30 ENSDART00000153167
hlfb
hepatic leukemia factor b
chr7_-_27685365 0.30 ENSDART00000188342
calca
calcitonin/calcitonin-related polypeptide, alpha
chr4_+_4267451 0.30 ENSDART00000192069
ano2
anoctamin 2
chr23_-_4019699 0.30 ENSDART00000159780
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr21_+_45496442 0.29 ENSDART00000164880
si:dkey-223p19.1
si:dkey-223p19.1
chr12_-_44171241 0.29 ENSDART00000169233
ENSDART00000165496
si:dkey-31i7.2
si:dkey-31i7.2
chr20_+_3339248 0.29 ENSDART00000108955
mfsd4b
major facilitator superfamily domain containing 4B
chr20_-_39188476 0.29 ENSDART00000152858
rcan2
regulator of calcineurin 2
chr8_-_18899427 0.29 ENSDART00000079840
rorca
RAR-related orphan receptor C a
chr10_+_466926 0.28 ENSDART00000145220
arvcfa
ARVCF, delta catenin family member a
chr2_+_394166 0.28 ENSDART00000155733
mylk4a
myosin light chain kinase family, member 4a
chr13_+_28417297 0.28 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr8_-_17067364 0.28 ENSDART00000132687
rab3c
RAB3C, member RAS oncogene family
chr21_+_45627775 0.28 ENSDART00000185466
irf1b
interferon regulatory factor 1b
chr1_+_55137943 0.28 ENSDART00000138070
ENSDART00000150510
ENSDART00000133472
ENSDART00000136378
mb
myoglobin
chr21_-_20939488 0.28 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr8_+_25352268 0.28 ENSDART00000187829
dnase1l1l
deoxyribonuclease I-like 1-like
chr2_-_12502495 0.27 ENSDART00000186781
dpp6b
dipeptidyl-peptidase 6b
chr17_+_35362851 0.27 ENSDART00000137659
cmpk2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr6_-_49510553 0.27 ENSDART00000166238
rplp2
ribosomal protein, large P2
chr13_-_11667661 0.27 ENSDART00000102411
dctn1b
dynactin 1b
chr13_+_32446169 0.27 ENSDART00000143325
nt5c1ba
5'-nucleotidase, cytosolic IB a
chr3_-_60316118 0.27 ENSDART00000171458
si:ch211-214b16.2
si:ch211-214b16.2
chr7_+_10610791 0.27 ENSDART00000166064
fah
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr12_+_29055143 0.27 ENSDART00000076322
gabrz
gamma-aminobutyric acid (GABA) A receptor, zeta
chr23_+_20408227 0.27 ENSDART00000134727
si:rp71-17i16.4
si:rp71-17i16.4
chr17_+_52823015 0.27 ENSDART00000160507
ENSDART00000186979
meis2a
Meis homeobox 2a
chr16_-_3678976 0.27 ENSDART00000111823
GRIK3
glutamate ionotropic receptor kainate type subunit 3
chr16_-_35329803 0.27 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr1_+_57187794 0.27 ENSDART00000152485
si:dkey-27j5.9
si:dkey-27j5.9
chr4_+_9612574 0.27 ENSDART00000150336
ENSDART00000041289
ENSDART00000150828
tmem243b
transmembrane protein 243, mitochondrial b
chr21_+_37445871 0.26 ENSDART00000076333
pgk1
phosphoglycerate kinase 1
chr2_-_24369087 0.26 ENSDART00000081237
plvapa
plasmalemma vesicle associated protein a
chr4_-_815871 0.26 ENSDART00000067455
dpysl5b
dihydropyrimidinase-like 5b
chr3_-_28750495 0.26 ENSDART00000054408
gsg1l
gsg1-like
chr20_-_54564018 0.26 ENSDART00000099832
zgc:153012
zgc:153012
chr9_-_49493305 0.26 ENSDART00000148707
ENSDART00000148561
xirp2b
xin actin binding repeat containing 2b
chr18_-_49286381 0.26 ENSDART00000174248
ENSDART00000174038
si:zfos-464b6.2
si:zfos-464b6.2

Network of associatons between targets according to the STRING database.

First level regulatory network of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 3.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.3 0.8 GO:0042942 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.2 0.7 GO:0002432 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.2 0.6 GO:0097376 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.2 1.3 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.2 0.7 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 0.8 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.4 GO:0018315 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 1.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 0.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 0.6 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.7 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.7 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.7 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 1.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.5 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.3 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.6 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.1 0.8 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 1.0 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.7 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.1 0.8 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.3 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 0.4 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 1.4 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 1.1 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.3 GO:0030327 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.1 0.6 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.9 GO:0014823 response to activity(GO:0014823)
0.1 0.2 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 1.8 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 1.9 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 1.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 1.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.7 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.2 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.1 GO:0055057 neuroblast division(GO:0055057)
0.0 0.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.1 GO:0043084 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.4 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 1.4 GO:0021854 hypothalamus development(GO:0021854)
0.0 3.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.8 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.3 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 0.1 GO:0003272 endocardial cushion formation(GO:0003272)
0.0 0.1 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 0.2 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.8 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 1.1 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.1 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.6 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 1.9 GO:0071565 nBAF complex(GO:0071565)
0.1 1.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.4 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 1.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.5 1.6 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.3 1.0 GO:0045545 syndecan binding(GO:0045545)
0.2 0.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 1.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.7 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.2 1.4 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.5 GO:0001729 ceramide kinase activity(GO:0001729)
0.2 0.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 1.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.7 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 1.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.4 GO:0043495 protein anchor(GO:0043495)
0.1 0.5 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.4 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.3 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 1.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 6.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.1 0.7 GO:0030332 cyclin binding(GO:0030332)
0.1 0.2 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.6 GO:0008483 transaminase activity(GO:0008483)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.6 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 2.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.5 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 1.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.3 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.0 0.4 GO:0004568 chitinase activity(GO:0004568)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0030882 lipid antigen binding(GO:0030882)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 2.3 GO:0019838 growth factor binding(GO:0019838)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 1.2 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 3.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation