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PRJEB1986: zebrafish developmental stages transcriptome

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Results for mixl1+mxtx1+sebox

Z-value: 0.39

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Transcription factors associated with mixl1+mxtx1+sebox

Gene Symbol Gene ID Gene Info
sebox
ENSDARG00000042526 SEBOX homeobox
mixl1
ENSDARG00000069252 Mix paired-like homeobox
mxtx1
ENSDARG00000069382 mix-type homeobox gene 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mxtx1dr11_v1_chr13_-_21660203_216602030.923.4e-08Click!
seboxdr11_v1_chr5_+_67371650_67371650-0.493.3e-02Click!
mixl1dr11_v1_chr20_-_43723860_437238600.446.0e-02Click!

Activity profile of mixl1+mxtx1+sebox motif

Sorted Z-values of mixl1+mxtx1+sebox motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_15440841 1.26 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr16_+_29509133 1.25 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr19_+_15441022 1.06 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr23_-_17003533 0.98 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr1_-_55248496 0.94 ENSDART00000098615
nanos3
nanos homolog 3
chr21_-_23331619 0.81 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr17_+_16046132 0.76 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr17_+_16046314 0.73 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr18_+_19456648 0.71 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr5_-_12219572 0.66 ENSDART00000167834
nos1
nitric oxide synthase 1 (neuronal)
chr17_+_21295132 0.65 ENSDART00000103845
eno4
enolase family member 4
chr11_-_35171162 0.60 ENSDART00000017393
traip
TRAF-interacting protein
chr2_+_33326522 0.58 ENSDART00000056655
klf17
Kruppel-like factor 17
chr14_+_22113331 0.58 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr16_-_29387215 0.58 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr17_-_16422654 0.58 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr6_+_41191482 0.58 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr16_-_16761164 0.56 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr23_+_31912882 0.55 ENSDART00000140505
armc1l
armadillo repeat containing 1, like
chr6_-_40922971 0.54 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr15_+_36309070 0.54 ENSDART00000157034
gmnc
geminin coiled-coil domain containing
chr22_+_16535575 0.52 ENSDART00000083063
tal1
T-cell acute lymphocytic leukemia 1
chr12_-_35830625 0.52 ENSDART00000180028
CU459056.1

chr8_+_23355484 0.51 ENSDART00000085361
ENSDART00000125729
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr3_+_18807006 0.50 ENSDART00000180091
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr14_-_22113600 0.50 ENSDART00000113752
si:dkey-6i22.5
si:dkey-6i22.5
chr7_+_56098590 0.49 ENSDART00000098453
cdh15
cadherin 15, type 1, M-cadherin (myotubule)
chr22_-_15593824 0.49 ENSDART00000123125
tpm4a
tropomyosin 4a
chr13_+_35637048 0.48 ENSDART00000085037
thbs2a
thrombospondin 2a
chr10_-_21362320 0.48 ENSDART00000189789
avd
avidin
chr21_+_43404945 0.47 ENSDART00000142234
frmd7
FERM domain containing 7
chr16_-_17347727 0.46 ENSDART00000144392
zyx
zyxin
chr17_+_8799451 0.46 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr10_-_21362071 0.45 ENSDART00000125167
avd
avidin
chr24_+_19415124 0.45 ENSDART00000186931
sulf1
sulfatase 1
chr1_+_21731382 0.45 ENSDART00000054395
pax5
paired box 5
chr21_+_15592426 0.45 ENSDART00000138207
smarcb1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr23_-_31913069 0.45 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr20_-_23426339 0.44 ENSDART00000004625
zar1
zygote arrest 1
chr13_+_27232848 0.44 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr8_-_37249813 0.44 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
rbm39b
RNA binding motif protein 39b
chr23_+_31913292 0.43 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr2_+_6253246 0.43 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr2_+_20793982 0.43 ENSDART00000014785
prg4a
proteoglycan 4a
chr21_+_34088110 0.42 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr2_+_41526904 0.41 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr23_-_31913231 0.40 ENSDART00000146852
ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr4_+_11723852 0.40 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr20_-_20930926 0.40 ENSDART00000123909
btbd6b
BTB (POZ) domain containing 6b
chr6_+_40922572 0.40 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_-_16719244 0.39 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr17_-_31695217 0.39 ENSDART00000104332
ENSDART00000143090
lin52
lin-52 DREAM MuvB core complex component
chr14_-_33945692 0.38 ENSDART00000168546
ENSDART00000189778
zdhhc24
zinc finger, DHHC-type containing 24
chr3_+_28860283 0.38 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr13_+_22295905 0.38 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr13_-_31017960 0.38 ENSDART00000145287
wdfy4
WDFY family member 4
chr2_-_55298075 0.37 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr11_+_33818179 0.37 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr3_+_26244353 0.37 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr11_-_30158191 0.36 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr4_+_9177997 0.36 ENSDART00000057254
ENSDART00000154614
nfyba
nuclear transcription factor Y, beta a
chr24_+_21540842 0.36 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr19_+_30884706 0.35 ENSDART00000052126
yars
tyrosyl-tRNA synthetase
chr16_+_28994709 0.35 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr19_+_2631565 0.34 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr15_+_1534644 0.33 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr14_+_6962271 0.33 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr9_+_29548195 0.32 ENSDART00000176057
rnf17
ring finger protein 17
chr15_+_857148 0.32 ENSDART00000156949
si:dkey-7i4.13
si:dkey-7i4.13
chr6_-_8311044 0.32 ENSDART00000129674
slc44a2
solute carrier family 44 (choline transporter), member 2
chr15_-_2519640 0.32 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr11_-_41220794 0.31 ENSDART00000192895
mrps16
mitochondrial ribosomal protein S16
chr1_-_45616470 0.31 ENSDART00000150165
atf7ip
activating transcription factor 7 interacting protein
chr3_-_30488063 0.31 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr24_-_4450238 0.31 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr3_-_39695856 0.31 ENSDART00000148247
b9d1
B9 protein domain 1
chr21_-_17296789 0.31 ENSDART00000192180
gfi1b
growth factor independent 1B transcription repressor
chr20_-_20931197 0.31 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr23_+_11285662 0.31 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr23_-_25135046 0.31 ENSDART00000184844
ENSDART00000103989
idh3g
isocitrate dehydrogenase 3 (NAD+) gamma
chr5_+_35786141 0.30 ENSDART00000022043
ENSDART00000127383
stard8
StAR-related lipid transfer (START) domain containing 8
chr8_+_50953776 0.29 ENSDART00000013870
zgc:56596
zgc:56596
chr13_+_25486608 0.29 ENSDART00000057689
bag3
BCL2 associated athanogene 3
chr16_-_42056137 0.29 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr24_-_2450597 0.29 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr2_-_30668580 0.29 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr6_+_21001264 0.29 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr3_-_26244256 0.27 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr16_+_42471455 0.27 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr11_+_35171406 0.27 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr5_+_52167986 0.26 ENSDART00000162256
ENSDART00000073626
slc14a2
solute carrier family 14 (urea transporter), member 2
chr23_+_39695827 0.26 ENSDART00000113893
ENSDART00000186679
tmco4
transmembrane and coiled-coil domains 4
chr24_-_37640705 0.26 ENSDART00000066583
zgc:112496
zgc:112496
chr4_-_5455506 0.26 ENSDART00000156593
ENSDART00000154676
si:dkey-14d8.22
si:dkey-14d8.22
chr14_-_33481428 0.26 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr10_+_6884627 0.26 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr9_+_25776971 0.25 ENSDART00000146011
zeb2a
zinc finger E-box binding homeobox 2a
chr13_-_12602920 0.25 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr11_-_45138857 0.25 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr5_-_14326959 0.25 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr15_-_2493771 0.25 ENSDART00000184906
neu4
sialidase 4
chr11_+_31864921 0.24 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr17_-_40956035 0.24 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr1_-_26444075 0.24 ENSDART00000125690
ints12
integrator complex subunit 12
chr1_-_43727012 0.24 ENSDART00000181064
bdh2
3-hydroxybutyrate dehydrogenase, type 2
chr9_-_31278048 0.24 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr14_+_34490445 0.24 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr21_+_25777425 0.24 ENSDART00000021620
cldnd
claudin d
chr13_+_1132261 0.24 ENSDART00000146049
wdr92
WD repeat domain 92
chr12_+_16087077 0.23 ENSDART00000141898
znf281b
zinc finger protein 281b
chr15_-_18115540 0.23 ENSDART00000131639
ENSDART00000047902
arcn1b
archain 1b
chr16_+_33902006 0.23 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr12_+_48803098 0.23 ENSDART00000074768
ppifb
peptidylprolyl isomerase Fb
chr21_-_11654422 0.23 ENSDART00000081614
ENSDART00000132699
cast
calpastatin
chr16_-_43344859 0.23 ENSDART00000058680
psma2
proteasome subunit alpha 2
chr17_-_25649079 0.23 ENSDART00000130955
ppp1cb
protein phosphatase 1, catalytic subunit, beta isozyme
chr3_-_39696066 0.23 ENSDART00000015393
b9d1
B9 protein domain 1
chr24_+_32668675 0.22 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
si:ch211-282b22.1
chr3_+_46635527 0.22 ENSDART00000153971
si:dkey-248g21.1
si:dkey-248g21.1
chr11_-_30634286 0.22 ENSDART00000191019
zgc:153665
zgc:153665
chr17_-_20118145 0.22 ENSDART00000149737
ENSDART00000165606
ryr2b
ryanodine receptor 2b (cardiac)
chr3_+_45365098 0.22 ENSDART00000052746
ENSDART00000156555
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr15_-_16177603 0.21 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr13_-_36535128 0.21 ENSDART00000043312
srsf5a
serine/arginine-rich splicing factor 5a
chr6_-_12172424 0.20 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr18_+_30028135 0.20 ENSDART00000140825
ENSDART00000145306
ENSDART00000136810
si:ch211-220f16.1
si:ch211-220f16.1
chr8_+_45334255 0.19 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr17_+_46818521 0.19 ENSDART00000156022
pimr14
Pim proto-oncogene, serine/threonine kinase, related 14
chr3_+_45364849 0.19 ENSDART00000153974
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr8_+_41037541 0.19 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr7_+_34592526 0.19 ENSDART00000173959
fhod1
formin homology 2 domain containing 1
chr4_-_20292821 0.19 ENSDART00000136069
ENSDART00000192504
cacna2d4a
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr8_-_37249991 0.19 ENSDART00000189275
ENSDART00000178556
rbm39b
RNA binding motif protein 39b
chr1_+_33668236 0.18 ENSDART00000122316
ENSDART00000102184
arl13b
ADP-ribosylation factor-like 13b
chr5_+_28770273 0.18 ENSDART00000114473
trafd1
TRAF-type zinc finger domain containing 1
chr7_+_19495379 0.17 ENSDART00000180514
si:ch211-212k18.8
si:ch211-212k18.8
chr18_-_19456269 0.17 ENSDART00000060363
rpl4
ribosomal protein L4
chr21_-_36453594 0.17 ENSDART00000193176
cnot8
CCR4-NOT transcription complex, subunit 8
chr11_+_26604224 0.17 ENSDART00000030453
ENSDART00000168895
ENSDART00000159505
dynlrb1
dynein, light chain, roadblock-type 1
chr19_+_40069524 0.17 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr19_-_30524952 0.17 ENSDART00000103506
hpcal4
hippocalcin like 4
chr9_-_20372977 0.16 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr17_-_23416897 0.16 ENSDART00000163391
si:ch211-149k12.3
si:ch211-149k12.3
chr15_+_34988148 0.16 ENSDART00000076269
ccdc105
coiled-coil domain containing 105
chr8_+_21353878 0.16 ENSDART00000056420
alas2
aminolevulinate, delta-, synthase 2
chr21_-_25801956 0.15 ENSDART00000101219
mettl27
methyltransferase like 27
chr12_-_14143344 0.15 ENSDART00000152742
buc2l
bucky ball 2-like
chr16_+_6750756 0.15 ENSDART00000149720
znf236
zinc finger protein 236
chr24_-_30862168 0.15 ENSDART00000168540
ptbp2a
polypyrimidine tract binding protein 2a
chr2_-_57378748 0.15 ENSDART00000149235
tcf3a
transcription factor 3a
chr3_-_30685401 0.14 ENSDART00000151097
si:ch211-51c14.1
si:ch211-51c14.1
chr24_+_12835935 0.14 ENSDART00000114762
nanog
nanog homeobox
chr4_-_43388943 0.14 ENSDART00000150796
si:dkey-29j8.2
si:dkey-29j8.2
chr15_-_43284021 0.14 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr25_-_2723682 0.13 ENSDART00000113382
adpgk
ADP-dependent glucokinase
chr21_-_35419486 0.13 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr8_-_25033681 0.13 ENSDART00000003493
nfyal
nuclear transcription factor Y, alpha, like
chr24_+_9412450 0.13 ENSDART00000132724
si:ch211-285f17.1
si:ch211-285f17.1
chr21_+_34088377 0.12 ENSDART00000170070
mtmr1b
myotubularin related protein 1b
chr7_+_26649319 0.12 ENSDART00000173823
ENSDART00000101053
tp53i11a
tumor protein p53 inducible protein 11a
chr9_-_21918963 0.12 ENSDART00000090782
lmo7a
LIM domain 7a
chr6_+_50381665 0.12 ENSDART00000141128
cyc1
cytochrome c-1
chr19_-_19379084 0.12 ENSDART00000165206
smarcc1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr11_+_18873113 0.11 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr3_+_32365811 0.11 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr18_-_29896367 0.11 ENSDART00000191303
cmc2
C-x(9)-C motif containing 2
chr5_-_20491198 0.11 ENSDART00000183051
ENSDART00000144232
ficd
FIC domain containing
chr1_+_8694196 0.11 ENSDART00000025604
zgc:77849
zgc:77849
chr10_+_40660772 0.11 ENSDART00000148007
taar19l
trace amine associated receptor 19l
chr14_+_44794936 0.11 ENSDART00000128881
zgc:195212
zgc:195212
chr8_+_25034544 0.11 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr14_+_45406299 0.10 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr10_+_21867307 0.10 ENSDART00000126629
cbln17
cerebellin 17
chr15_-_41332865 0.10 ENSDART00000170014
si:dkey-121n8.7
si:dkey-121n8.7
chr22_+_31207799 0.09 ENSDART00000133267
grip2b
glutamate receptor interacting protein 2b
chr17_+_37227936 0.09 ENSDART00000076009
hadhab
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
chr5_-_37871526 0.09 ENSDART00000136450
arhgap35b
Rho GTPase activating protein 35b
chr20_+_52554352 0.09 ENSDART00000153217
ENSDART00000145230
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr14_+_34492288 0.08 ENSDART00000144301
wnt8a
wingless-type MMTV integration site family, member 8a
chr6_+_50381347 0.08 ENSDART00000055504
cyc1
cytochrome c-1
chr8_+_11425048 0.08 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr15_+_5360407 0.08 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr18_-_40708537 0.08 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr9_-_746317 0.07 ENSDART00000129632
ENSDART00000130720
usp37
ubiquitin specific peptidase 37
chr24_-_3783497 0.07 ENSDART00000158354
adarb2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr20_-_9095105 0.07 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr4_+_2655358 0.07 ENSDART00000007638
bcap29
B cell receptor associated protein 29
chr18_+_24921587 0.07 ENSDART00000191345
rgma
repulsive guidance molecule family member a
chr24_-_6078222 0.07 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr16_-_29458806 0.06 ENSDART00000047931
lingo4b
leucine rich repeat and Ig domain containing 4b
chr21_+_5272059 0.06 ENSDART00000141981
loxhd1a
lipoxygenase homology domains 1a
chr11_-_1550709 0.06 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr13_-_24311628 0.06 ENSDART00000004420
rab4a
RAB4a, member RAS oncogene family
chr17_+_23298928 0.06 ENSDART00000153652
zgc:165461
zgc:165461
chr24_-_40860603 0.06 ENSDART00000188032
CU633479.7

chr10_-_25217347 0.06 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chrM_+_3803 0.05 ENSDART00000093596
mt-nd1
NADH dehydrogenase 1, mitochondrial
chr21_-_39177564 0.05 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr3_+_18398876 0.05 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr2_-_32384683 0.05 ENSDART00000182942
ENSDART00000141757
ubtfl
upstream binding transcription factor, like

Network of associatons between targets according to the STRING database.

First level regulatory network of mixl1+mxtx1+sebox

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.7 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.2 1.0 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 0.6 GO:0048785 hatching gland development(GO:0048785)
0.2 0.5 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.6 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 0.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.3 GO:0060898 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.4 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 0.4 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.3 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.4 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.3 GO:0015871 choline transport(GO:0015871)
0.1 0.7 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 0.8 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.2 GO:0051645 Golgi localization(GO:0051645)
0.1 0.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.3 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.4 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.2 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.7 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.3 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.9 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.5 GO:0031297 replication fork processing(GO:0031297)
0.0 0.5 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0060021 palate development(GO:0060021)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.3 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.3 GO:0097189 apoptotic body(GO:0097189)
0.1 0.3 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.4 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.3 GO:0035060 brahma complex(GO:0035060)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.0 GO:0043186 P granule(GO:0043186)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.0 0.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0000777 condensed chromosome kinetochore(GO:0000777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.2 0.9 GO:0009374 biotin binding(GO:0009374)
0.1 1.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.5 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.7 GO:0032190 acrosin binding(GO:0032190)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.6 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA