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PRJEB1986: zebrafish developmental stages transcriptome

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Results for msx1a

Z-value: 1.01

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Transcription factors associated with msx1a

Gene Symbol Gene ID Gene Info
msx1a
ENSDARG00000116118 muscle segment homeobox 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx1adr11_v1_chr14_-_12822_12847-0.923.0e-08Click!

Activity profile of msx1a motif

Sorted Z-values of msx1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_12270857 5.03 ENSDART00000170093
si:dkey-36i7.3
si:dkey-36i7.3
chr11_+_30244356 4.05 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr3_-_50443607 3.88 ENSDART00000074036
rcvrna
recoverin a
chr23_+_40460333 3.62 ENSDART00000184658
soga3b
SOGA family member 3b
chr17_-_12389259 3.62 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr25_-_10503043 3.56 ENSDART00000155404
cox8b
cytochrome c oxidase subunit 8b
chr19_+_10339538 3.45 ENSDART00000151808
ENSDART00000151235
rcvrn3
recoverin 3
chr12_+_24342303 3.27 ENSDART00000111239
nrxn1a
neurexin 1a
chr2_+_39021282 3.00 ENSDART00000056577
RBP1 (1 of many)
si:ch211-119o8.7
chr20_-_40755614 2.61 ENSDART00000061247
cx32.3
connexin 32.3
chr13_+_28701233 2.49 ENSDART00000135931
si:ch211-67n3.9
si:ch211-67n3.9
chr1_-_50859053 2.46 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr20_+_30490682 2.40 ENSDART00000184871
myt1la
myelin transcription factor 1-like, a
chr25_-_32869794 2.36 ENSDART00000162784
tmem266
transmembrane protein 266
chr3_-_32169754 2.19 ENSDART00000179010
tnnt1
troponin T type 1 (skeletal, slow)
chr22_+_35068046 2.18 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr5_-_23280098 2.17 ENSDART00000126540
ENSDART00000051533
plp1b
proteolipid protein 1b
chr12_+_6195191 2.15 ENSDART00000043236
ENSDART00000186420
prkg1b
protein kinase, cGMP-dependent, type Ib
chr23_-_28141419 2.14 ENSDART00000133039
tac3a
tachykinin 3a
chr6_+_3828560 2.08 ENSDART00000185273
ENSDART00000179091
gad1b
glutamate decarboxylase 1b
chr16_+_5774977 2.07 ENSDART00000134202
ccka
cholecystokinin a
chr4_+_12612723 2.05 ENSDART00000133767
lmo3
LIM domain only 3
chr18_+_15644559 2.05 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr16_-_29437373 1.94 ENSDART00000148405
si:ch211-113g11.6
si:ch211-113g11.6
chr15_-_6247775 1.91 ENSDART00000148350
dscamb
Down syndrome cell adhesion molecule b
chr2_-_33645411 1.85 ENSDART00000114663
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr8_-_46894362 1.85 ENSDART00000111124
acot7
acyl-CoA thioesterase 7
chr18_-_16801033 1.84 ENSDART00000100100
admb
adrenomedullin b
chr2_+_50626476 1.83 ENSDART00000018150
neurod6b
neuronal differentiation 6b
chr2_+_31804582 1.82 ENSDART00000086646
rnf182
ring finger protein 182
chr20_-_29420713 1.76 ENSDART00000147464
ryr3
ryanodine receptor 3
chr15_+_9053059 1.74 ENSDART00000012039
ppm1na
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr14_-_2933185 1.73 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr24_-_24849091 1.69 ENSDART00000133649
ENSDART00000038290
crhb
corticotropin releasing hormone b
chr16_-_47483142 1.67 ENSDART00000147072
cthrc1b
collagen triple helix repeat containing 1b
chr4_+_11384891 1.66 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
pcloa
piccolo presynaptic cytomatrix protein a
chr22_+_28320792 1.58 ENSDART00000160562
ENSDART00000164138
impg2b
impg2b
interphotoreceptor matrix proteoglycan 2b
interphotoreceptor matrix proteoglycan 2b
chr2_+_50608099 1.57 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr13_-_44630111 1.56 ENSDART00000110092
mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr23_-_1348933 1.53 ENSDART00000168981
CABZ01078120.1

chr20_-_32110882 1.53 ENSDART00000030324
grm1a
glutamate receptor, metabotropic 1a
chr13_+_38430466 1.50 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr22_-_10486477 1.49 ENSDART00000184366
aspn
asporin (LRR class 1)
chr19_-_8604429 1.45 ENSDART00000151165
trim46b
tripartite motif containing 46b
chr23_+_28582865 1.42 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr19_-_38830582 1.41 ENSDART00000189966
ENSDART00000183055
adgrb2
adhesion G protein-coupled receptor B2
chr7_+_32722227 1.37 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr13_+_25449681 1.36 ENSDART00000101328
atoh7
atonal bHLH transcription factor 7
chr21_+_6751405 1.34 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr23_+_33963619 1.27 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr10_+_42690374 1.27 ENSDART00000123496
rhobtb2b
Rho-related BTB domain containing 2b
chr8_+_22582146 1.26 ENSDART00000157655
ENSDART00000189892
CT583651.2

chr13_-_20381485 1.25 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr18_+_10884996 1.24 ENSDART00000147613
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr12_+_2446837 1.24 ENSDART00000112032
ARHGAP22
si:dkey-191m6.4
chr1_+_18811679 1.23 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr12_+_28749189 1.23 ENSDART00000013980
tbx21
T-box 21
chr11_+_12052791 1.23 ENSDART00000158479
si:ch211-156l18.8
si:ch211-156l18.8
chr22_+_20427170 1.21 ENSDART00000136744
foxq2
forkhead box Q2
chr22_-_13649588 1.18 ENSDART00000131877
si:ch211-279g13.1
si:ch211-279g13.1
chr14_-_2364761 1.14 ENSDART00000167322
PCDHGC3 (1 of many)
si:ch73-233f7.3
chr6_-_14292307 1.14 ENSDART00000177852
ENSDART00000061745
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr10_-_13343831 1.13 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr13_-_36911118 1.12 ENSDART00000048739
trim9
tripartite motif containing 9
chr6_-_6487876 1.12 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr22_-_23253481 1.12 ENSDART00000054807
lhx9
LIM homeobox 9
chr14_-_30587814 1.10 ENSDART00000144912
ENSDART00000149714
tmem265
transmembrane protein 265
chr16_+_31804590 1.07 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr7_-_23996133 1.06 ENSDART00000173761
si:dkey-183c6.8
si:dkey-183c6.8
chr18_-_43884044 1.06 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr2_-_57076687 1.05 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr12_+_31744217 1.04 ENSDART00000190361
RNF157
si:dkey-49c17.3
chr22_-_7129631 1.04 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr5_+_60928576 1.04 ENSDART00000131041
doc2b
double C2-like domains, beta
chr22_+_5176693 1.03 ENSDART00000160927
cers1
ceramide synthase 1
chr22_+_18477934 1.03 ENSDART00000132684
cilp2
cartilage intermediate layer protein 2
chr7_+_30787903 1.02 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr10_+_3049636 1.02 ENSDART00000081794
ENSDART00000183167
ENSDART00000191634
ENSDART00000183514
rasgrf2a
Ras protein-specific guanine nucleotide-releasing factor 2a
chr6_+_23887314 1.02 ENSDART00000163188
znf648
zinc finger protein 648
chr11_+_7264457 0.99 ENSDART00000154182
reep6
receptor accessory protein 6
chr7_-_28148310 0.99 ENSDART00000044208
lmo1
LIM domain only 1
chr20_-_46362606 0.99 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr17_-_23616626 0.98 ENSDART00000104730
ifit14
interferon-induced protein with tetratricopeptide repeats 14
chr21_+_6751760 0.98 ENSDART00000135914
olfm1b
olfactomedin 1b
chr25_+_19149241 0.98 ENSDART00000184982
ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr1_-_47071979 0.97 ENSDART00000160817
itsn1
intersectin 1 (SH3 domain protein)
chr7_-_36096582 0.95 ENSDART00000188507
CR848715.1

chr2_+_37227011 0.95 ENSDART00000126587
ENSDART00000084958
samd7
sterile alpha motif domain containing 7
chr8_-_20230559 0.94 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr16_+_39159752 0.94 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr6_-_44711942 0.93 ENSDART00000055035
cntn3b
contactin 3b
chr5_-_67629263 0.89 ENSDART00000133753
zbtb20
zinc finger and BTB domain containing 20
chr3_-_32337653 0.89 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr24_-_31846366 0.88 ENSDART00000155295
steap2
STEAP family member 2, metalloreductase
chr11_-_42554290 0.84 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr2_+_21229909 0.81 ENSDART00000046127
vipr1a
vasoactive intestinal peptide receptor 1a
chr19_-_42391383 0.79 ENSDART00000110075
ENSDART00000087002
plekho1a
pleckstrin homology domain containing, family O member 1a
chr6_+_3280939 0.79 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr15_-_22074315 0.78 ENSDART00000149830
drd2a
dopamine receptor D2a
chr10_+_16584382 0.76 ENSDART00000112039
CR790388.1

chr18_-_2433011 0.75 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr15_-_34785594 0.71 ENSDART00000154256
gabbr1a
gamma-aminobutyric acid (GABA) B receptor, 1a
chr19_+_42470396 0.71 ENSDART00000191679
si:dkey-166k12.1
si:dkey-166k12.1
chr12_-_20120702 0.71 ENSDART00000153387
ENSDART00000158412
ENSDART00000112768
ubald1a
UBA-like domain containing 1a
chr6_+_39232245 0.68 ENSDART00000187351
b4galnt1b
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr16_-_27628994 0.68 ENSDART00000157407
nacad
NAC alpha domain containing
chr17_+_33311784 0.67 ENSDART00000156229
si:ch211-132f19.7
si:ch211-132f19.7
chr20_-_32270866 0.65 ENSDART00000153140
armc2
armadillo repeat containing 2
chr20_-_28800999 0.63 ENSDART00000049462
rab15
RAB15, member RAS oncogene family
chr22_-_10121880 0.62 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr20_-_45060241 0.62 ENSDART00000185227
klhl29
kelch-like family member 29
chr8_+_26125218 0.61 ENSDART00000145095
celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr2_-_23004286 0.60 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr8_+_26253252 0.60 ENSDART00000142031
slc26a6
solute carrier family 26, member 6
chr10_+_21867307 0.57 ENSDART00000126629
cbln17
cerebellin 17
chr4_-_15420452 0.57 ENSDART00000016230
plxna4
plexin A4
chr21_-_3853204 0.56 ENSDART00000188829
st6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr1_-_36152131 0.56 ENSDART00000182113
ENSDART00000182904
znf827
zinc finger protein 827
chr13_+_2625150 0.56 ENSDART00000164177
plpp4
phospholipid phosphatase 4
chr25_-_27621268 0.54 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr1_-_18811517 0.53 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr21_-_8085635 0.52 ENSDART00000082790
si:dkey-163m14.2
si:dkey-163m14.2
chr7_-_31941330 0.52 ENSDART00000144682
bdnf
brain-derived neurotrophic factor
chr22_+_5176255 0.52 ENSDART00000092647
cers1
ceramide synthase 1
chr9_+_24008879 0.51 ENSDART00000190419
ENSDART00000191843
ENSDART00000148226
mlphb
melanophilin b
chr17_+_31914877 0.48 ENSDART00000177801
FAM196A (1 of many)
family with sequence similarity 196 member A
chr24_-_4782052 0.47 ENSDART00000149911
agtr1b
angiotensin II receptor, type 1b
chr11_-_7261717 0.45 ENSDART00000128959
zgc:113223
zgc:113223
chr9_+_34331368 0.45 ENSDART00000147913
pou2f1b
POU class 2 homeobox 1b
chr3_+_56366395 0.43 ENSDART00000154367
cacng5b
calcium channel, voltage-dependent, gamma subunit 5b
chr14_-_25034142 0.42 ENSDART00000000392
pde6a
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr3_-_32898626 0.42 ENSDART00000103201
kat7a
K(lysine) acetyltransferase 7a
chr20_+_19238382 0.41 ENSDART00000136757
fndc4a
fibronectin type III domain containing 4a
chr25_+_11456696 0.40 ENSDART00000171408
AGBL1
si:ch73-141f14.1
chr6_+_102506 0.39 ENSDART00000172678
ldlrb
low density lipoprotein receptor b
chr9_-_52962521 0.38 ENSDART00000170419
CU855885.1

chr10_-_28513861 0.38 ENSDART00000177781
bbx
bobby sox homolog (Drosophila)
chr12_+_21298317 0.36 ENSDART00000178562
ca10a
carbonic anhydrase Xa
chr10_-_34916208 0.35 ENSDART00000187371
ccna1
cyclin A1
chr6_+_9204099 0.34 ENSDART00000150167
ENSDART00000115394
tbx19
T-box 19
chr5_+_11290851 0.33 ENSDART00000180408
CABZ01077124.1

chr9_-_21918963 0.31 ENSDART00000090782
lmo7a
LIM domain 7a
chr15_-_23376541 0.31 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr4_-_72638972 0.31 ENSDART00000193312
CABZ01054394.1

chr11_-_29768054 0.31 ENSDART00000079117
plekha3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr10_-_32494304 0.30 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr19_-_19556778 0.29 ENSDART00000164060
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr12_-_18872927 0.28 ENSDART00000187717
shisa8b
shisa family member 8b
chr16_+_54263921 0.28 ENSDART00000002856
drd2l
dopamine receptor D2 like
chr15_+_23911655 0.28 ENSDART00000156304
si:ch1073-145m9.1
si:ch1073-145m9.1
chr24_+_40860320 0.24 ENSDART00000161351
gorasp1b
golgi reassembly stacking protein 1b
chr10_-_32494499 0.22 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr15_-_8665662 0.20 ENSDART00000090675
arhgap35a
Rho GTPase activating protein 35a
chr13_+_38990939 0.20 ENSDART00000145979
col19a1
collagen, type XIX, alpha 1
chr6_+_11850359 0.19 ENSDART00000109552
ENSDART00000188139
ENSDART00000181499
ENSDART00000178269
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr10_+_43039947 0.19 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr15_-_21877726 0.18 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr18_+_7204378 0.18 ENSDART00000142905
vwf
von Willebrand factor
chr1_+_34696503 0.18 ENSDART00000186106
CR339054.2

chr7_-_31940590 0.17 ENSDART00000131009
bdnf
brain-derived neurotrophic factor
chr25_+_10410620 0.17 ENSDART00000151886
ehf
ets homologous factor
chr15_-_26931541 0.16 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr7_-_12464412 0.15 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr6_-_39649504 0.14 ENSDART00000179960
ENSDART00000190951
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr22_+_1092479 0.14 ENSDART00000170119
guca1e
guanylate cyclase activator 1e
chrM_+_11009 0.13 ENSDART00000093617
mt-nd4l
NADH dehydrogenase 4L, mitochondrial
chr8_-_38477817 0.13 ENSDART00000075989
inpp5l
inositol polyphosphate-5-phosphatase L
chr4_-_9891874 0.13 ENSDART00000067193
adm2a
adrenomedullin 2a
chr12_+_20352400 0.13 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr20_-_29864390 0.12 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr16_-_16120941 0.12 ENSDART00000131227
ankib1b
ankyrin repeat and IBR domain containing 1b
chr21_-_20757866 0.11 ENSDART00000163003
ghrb
growth hormone receptor b
chr21_-_27338639 0.10 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr17_+_25856671 0.09 ENSDART00000064817
wapla
WAPL cohesin release factor a
chr20_-_11178022 0.09 ENSDART00000152246
flrt2
fibronectin leucine rich transmembrane protein 2
chr5_+_37032038 0.08 ENSDART00000045036
nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr13_-_36184476 0.08 ENSDART00000057185
map3k9
mitogen-activated protein kinase kinase kinase 9
chr4_+_16885854 0.08 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr10_-_21955231 0.08 ENSDART00000183695
FO744833.2

chr21_-_28640316 0.08 ENSDART00000128237
nrg2a
neuregulin 2a
chr19_+_7735157 0.07 ENSDART00000186717
tuft1b
tuftelin 1b
chr17_+_26543690 0.06 ENSDART00000156417
sparcl2
SPARC-like 2
chr23_+_38957472 0.04 ENSDART00000193836
ATP9A
ATPase phospholipid transporting 9A (putative)
chr8_-_25034411 0.02 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr8_+_25034544 0.01 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr7_-_23768234 0.01 ENSDART00000173981
si:ch211-200p22.4
si:ch211-200p22.4

Network of associatons between targets according to the STRING database.

First level regulatory network of msx1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.7 7.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.6 1.7 GO:0035902 response to immobilization stress(GO:0035902)
0.5 2.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.4 1.1 GO:0097376 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.3 1.0 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.3 2.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 1.5 GO:0016322 neuron remodeling(GO:0016322)
0.3 3.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.9 GO:0060074 synapse maturation(GO:0060074)
0.2 0.9 GO:0015677 copper ion import(GO:0015677)
0.2 0.6 GO:0007414 axonal defasciculation(GO:0007414)
0.2 1.7 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 1.0 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.1 GO:0034063 stress granule assembly(GO:0034063)
0.1 2.1 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 2.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 1.0 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.6 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 0.6 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.7 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 1.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.1 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.5 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 1.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.9 GO:0006825 copper ion transport(GO:0006825)
0.1 1.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 3.6 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 2.1 GO:0007586 digestion(GO:0007586)
0.0 1.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:0035627 ceramide transport(GO:0035627)
0.0 2.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 1.0 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 1.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 1.7 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.0 1.1 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.0 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.4 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 2.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 1.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 1.0 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.2 GO:0072676 lymphocyte migration(GO:0072676)
0.0 0.7 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.8 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 1.2 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.1 GO:0060347 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 1.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 1.5 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 3.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 1.7 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.8 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 2.2 GO:0043209 myelin sheath(GO:0043209)
0.1 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.7 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.0 2.0 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.1 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 4.7 GO:0030424 axon(GO:0030424)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.7 2.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 2.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.4 1.8 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.3 1.0 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 2.1 GO:0032052 bile acid binding(GO:0032052)
0.3 1.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.9 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 0.9 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 1.5 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 1.0 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 0.9 GO:0016531 copper chaperone activity(GO:0016531)
0.2 1.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 2.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.8 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 3.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.5 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.1 4.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.7 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.9 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.3 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 1.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.7 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 2.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 2.5 GO:0005179 hormone activity(GO:0005179)
0.0 1.2 GO:0071949 FAD binding(GO:0071949)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.1 GO:0019955 cytokine binding(GO:0019955)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases