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PRJEB1986: zebrafish developmental stages transcriptome

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Results for msx1b+msx3

Z-value: 0.77

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Transcription factors associated with msx1b+msx3

Gene Symbol Gene ID Gene Info
msx1b
ENSDARG00000008886 muscle segment homeobox 1b
msx3
ENSDARG00000015674 muscle segment homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx1bdr11_v1_chr1_+_49352900_493529000.707.8e-04Click!
msx3dr11_v1_chr13_+_24662238_246622380.561.2e-02Click!

Activity profile of msx1b+msx3 motif

Sorted Z-values of msx1b+msx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_23692462 1.62 ENSDART00000145934
hoxb7a
homeobox B7a
chr21_+_15592426 1.22 ENSDART00000138207
smarcb1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr9_-_32343673 1.17 ENSDART00000078499
rftn2
raftlin family member 2
chr7_-_8374950 1.13 ENSDART00000057101
aep1
aerolysin-like protein
chr20_-_9436521 1.11 ENSDART00000133000
zgc:101840
zgc:101840
chr4_-_77260727 1.06 ENSDART00000075770
zgc:162948
zgc:162948
chr20_+_11731039 1.02 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr14_+_9421510 1.02 ENSDART00000123652
hmgn6
high mobility group nucleosome binding domain 6
chr15_-_25518084 0.97 ENSDART00000158594
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr19_-_19871211 0.96 ENSDART00000170980
evx1
even-skipped homeobox 1
chr4_+_19700308 0.95 ENSDART00000027919
pax4
paired box 4
chr17_+_26352372 0.91 ENSDART00000155177
grid1a
glutamate receptor, ionotropic, delta 1a
chr16_-_7379328 0.91 ENSDART00000060447
med18
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)
chr3_+_32663865 0.89 ENSDART00000190240
si:dkey-16l2.16
si:dkey-16l2.16
chr5_+_29794058 0.89 ENSDART00000045410
thy1
Thy-1 cell surface antigen
chr13_+_30903816 0.88 ENSDART00000191727
ercc6
excision repair cross-complementation group 6
chr23_-_16485190 0.83 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr6_-_9695294 0.82 ENSDART00000162728
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr21_-_20328375 0.82 ENSDART00000079593
slc26a1
solute carrier family 26 (anion exchanger), member 1
chr13_+_18321140 0.80 ENSDART00000180947
eif4e1c
eukaryotic translation initiation factor 4E family member 1c
chr13_+_9468535 0.80 ENSDART00000135088
ENSDART00000164270
ENSDART00000099619
ENSDART00000164656
HTRA2 (1 of many)
si:dkey-265c15.6
chr24_+_22485710 0.78 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr13_-_9213207 0.76 ENSDART00000139861
ENSDART00000140524
HTRA2 (1 of many)
si:dkey-33c12.11
chr2_+_6253246 0.75 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr22_-_26274177 0.74 ENSDART00000060978
wdr83
WD repeat domain containing 83
chr21_-_38730557 0.73 ENSDART00000150984
ENSDART00000111885
taf9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr13_+_15701596 0.72 ENSDART00000130832
trmt61a
tRNA methyltransferase 61A
chr18_+_9171778 0.71 ENSDART00000101192
sema3d
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr25_+_14697247 0.69 ENSDART00000180747
mpped2
metallophosphoesterase domain containing 2b
chr16_-_41714988 0.66 ENSDART00000138798
cep85
centrosomal protein 85
chr15_-_20024205 0.65 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr25_+_19666621 0.65 ENSDART00000112746
zgc:171459
zgc:171459
chr21_+_723998 0.65 ENSDART00000160956
oaz1b
ornithine decarboxylase antizyme 1b
chr10_+_36178713 0.65 ENSDART00000140816
or108-3
odorant receptor, family D, subfamily 108, member 3
chr15_+_46344655 0.65 ENSDART00000155893
si:ch1073-340i21.2
si:ch1073-340i21.2
chr14_+_34490445 0.65 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr6_+_39370587 0.64 ENSDART00000157165
ENSDART00000155079
si:dkey-195m11.8
si:dkey-195m11.8
chr15_-_37683768 0.62 ENSDART00000059609
si:dkey-117a8.3
si:dkey-117a8.3
chr19_-_8768564 0.62 ENSDART00000170416
si:ch73-350k19.1
si:ch73-350k19.1
chr10_+_17235370 0.61 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr15_+_7057050 0.60 ENSDART00000061828
foxl2a
forkhead box L2a
chr3_-_31715714 0.59 ENSDART00000051542
ccdc47
coiled-coil domain containing 47
chr2_+_16487443 0.58 ENSDART00000114980
CR377211.1

chr1_+_55730205 0.58 ENSDART00000148075
adgre10
adhesion G protein-coupled receptor E10
chr24_-_7957581 0.57 ENSDART00000145815
txndc5
thioredoxin domain containing 5
chr21_+_6751760 0.57 ENSDART00000135914
olfm1b
olfactomedin 1b
chr15_+_36188171 0.57 ENSDART00000156598
masp1
mannan-binding lectin serine peptidase 1
chr15_-_37673733 0.56 ENSDART00000154513
si:dkey-117a8.4
si:dkey-117a8.4
chr17_-_22021213 0.56 ENSDART00000078843
zmp:0000001102
zmp:0000001102
chr16_-_26855936 0.55 ENSDART00000167320
ENSDART00000078119
ino80c
INO80 complex subunit C
chr24_+_17345521 0.54 ENSDART00000024722
ENSDART00000154250
ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr13_-_9045879 0.53 ENSDART00000155463
ENSDART00000140041
ENSDART00000137454
si:dkey-112g5.11
si:dkey-112g5.11
chr8_+_18555559 0.53 ENSDART00000149523
tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr13_+_23282549 0.52 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr13_-_9159852 0.52 ENSDART00000170185
ENSDART00000158697
ENSDART00000143393
ENSDART00000164973
ENSDART00000159910
HTRA2 (1 of many)
si:dkey-112g5.16
chr19_-_18127629 0.52 ENSDART00000187722
snx10a
sorting nexin 10a
chr24_-_17039638 0.52 ENSDART00000048823
c8g
complement component 8, gamma polypeptide
chr2_+_30032303 0.51 ENSDART00000151841
rbm33b
RNA binding motif protein 33b
chr16_+_33144306 0.51 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr23_+_44427188 0.51 ENSDART00000160207
eif4e2rs1
eukaryotic translation initiation factor 4E family member 2 related sequence 1
chr17_+_41081512 0.49 ENSDART00000056742
babam2
BRISC and BRCA1 A complex member 2
chr21_-_37973081 0.48 ENSDART00000136569
ripply1
ripply transcriptional repressor 1
chr15_+_15856178 0.48 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr3_-_31716157 0.47 ENSDART00000193189
ccdc47
coiled-coil domain containing 47
chr6_-_18971063 0.46 ENSDART00000188163
sept9b
septin 9b
chr17_+_24821627 0.45 ENSDART00000112389
wdr43
WD repeat domain 43
chr16_+_33144112 0.45 ENSDART00000183149
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr12_-_33357655 0.44 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr24_-_9979342 0.44 ENSDART00000138576
ENSDART00000191206
zgc:171977
zgc:171977
chr10_+_39212898 0.43 ENSDART00000159501
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr18_+_48423973 0.42 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr14_+_6535426 0.41 ENSDART00000055961
thg1l
tRNA-histidine guanylyltransferase 1-like
chr5_+_56023186 0.41 ENSDART00000156230
fzd9a
frizzled class receptor 9a
chr13_+_35955562 0.40 ENSDART00000137377
si:ch211-67f13.7
si:ch211-67f13.7
chr15_-_37709072 0.40 ENSDART00000157115
si:dkey-117a8.2
si:dkey-117a8.2
chr2_+_50608099 0.40 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr15_-_37620167 0.40 ENSDART00000059582
si:ch211-137j23.8
si:ch211-137j23.8
chr17_+_41081977 0.40 ENSDART00000137091
ENSDART00000143714
babam2
BRISC and BRCA1 A complex member 2
chr13_+_9521629 0.39 ENSDART00000149870
ENSDART00000137666
si:dkey-19p15.4
si:dkey-19p15.4
chr5_-_68093169 0.38 ENSDART00000051849
slc25a11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr3_+_34140507 0.38 ENSDART00000131802
si:dkey-204f11.64
si:dkey-204f11.64
chr19_-_18127808 0.37 ENSDART00000108627
snx10a
sorting nexin 10a
chr17_+_24851951 0.37 ENSDART00000180746
cx35.4
connexin 35.4
chr9_-_35633827 0.36 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr10_+_39212601 0.36 ENSDART00000168778
stt3a
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr15_-_14212777 0.36 ENSDART00000165572
CR925813.1

chr17_-_50071748 0.35 ENSDART00000075188
zgc:113886
zgc:113886
chr24_+_26345427 0.35 ENSDART00000089756
lrrc34
leucine rich repeat containing 34
chr16_+_41171949 0.35 ENSDART00000135294
nek11
NIMA-related kinase 11
chr6_+_52877147 0.34 ENSDART00000174370
or137-8
odorant receptor, family H, subfamily 137, member 8
chr21_-_22647695 0.34 ENSDART00000187553
gig2l
grass carp reovirus (GCRV)-induced gene 2l
chr11_-_40457325 0.33 ENSDART00000128442
tnfrsf1b
tumor necrosis factor receptor superfamily, member 1B
chr25_-_25550938 0.32 ENSDART00000150412
ENSDART00000103622
irf7
interferon regulatory factor 7
chr23_+_22658700 0.31 ENSDART00000192248
eno1a
enolase 1a, (alpha)
chr16_-_35975254 0.31 ENSDART00000167537
eva1ba
eva-1 homolog Ba (C. elegans)
chr20_-_19511016 0.30 ENSDART00000168521
snx17
sorting nexin 17
chr24_+_26345609 0.29 ENSDART00000186844
lrrc34
leucine rich repeat containing 34
chr15_-_31409013 0.28 ENSDART00000140456
or111-9
odorant receptor, family D, subfamily 111, member 9
chr11_-_25538341 0.28 ENSDART00000171560
si:dkey-245f22.3
si:dkey-245f22.3
chr10_+_11355841 0.28 ENSDART00000193067
ENSDART00000064215
cops4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr10_-_44560165 0.26 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr10_+_40568735 0.25 ENSDART00000136468
ENSDART00000182841
taar18i
trace amine associated receptor 18i
chr19_+_9212031 0.25 ENSDART00000052930
ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr24_+_38306010 0.25 ENSDART00000143184
mybpc2b
myosin binding protein C, fast type b
chr22_+_5532003 0.24 ENSDART00000106174
si:ch73-256j6.2
si:ch73-256j6.2
chr4_-_12997348 0.24 ENSDART00000171451
si:dkey-6a5.3
si:dkey-6a5.3
chr7_+_24496894 0.24 ENSDART00000149994
nelfa
negative elongation factor complex member A
chr8_-_15129573 0.23 ENSDART00000142358
bcar3
BCAR3, NSP family adaptor protein
chr17_+_7513673 0.22 ENSDART00000156674
klhl10b.1
kelch-like family member 10b, tandem duplicate 1
chr9_+_35832294 0.22 ENSDART00000130549
ENSDART00000122169
si:dkey-67c22.2
si:dkey-67c22.2
chr4_+_54519511 0.22 ENSDART00000161653
znf974
zinc finger protein 974
chr5_+_27897504 0.22 ENSDART00000130936
adam28
ADAM metallopeptidase domain 28
chr15_-_37733238 0.22 ENSDART00000115178
si:dkey-42l23.7
si:dkey-42l23.7
chr23_-_42876596 0.21 ENSDART00000086156
dlgap4a
discs, large (Drosophila) homolog-associated protein 4a
chr15_-_37767901 0.21 ENSDART00000154763
si:dkey-42l23.4
si:dkey-42l23.4
chr22_+_12770877 0.21 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr21_-_22648007 0.21 ENSDART00000121788
gig2l
grass carp reovirus (GCRV)-induced gene 2l
chr5_+_9224051 0.20 ENSDART00000139265
si:ch211-12e13.12
si:ch211-12e13.12
chr22_+_9114416 0.19 ENSDART00000190169
nlrp15
NACHT, LRR and PYD domains-containing protein 15
chr4_+_77047067 0.19 ENSDART00000174206
znf1009
zinc finger protein 1009
chr10_+_36194527 0.19 ENSDART00000076810
or108-1
odorant receptor, family D, subfamily 108, member 1
chr19_+_1673599 0.19 ENSDART00000163127
klhl7
kelch-like family member 7
chr10_+_40598791 0.19 ENSDART00000131895
taar17a
trace amine associated receptor 17a
chr19_+_8985230 0.18 ENSDART00000018973
scamp3
secretory carrier membrane protein 3
chr23_+_16889352 0.18 ENSDART00000145275
si:dkey-147f3.8
si:dkey-147f3.8
chr14_-_470505 0.18 ENSDART00000067147
ANKRD50
ankyrin repeat domain 50
chr9_+_18829360 0.17 ENSDART00000006514
gtf2f2b
general transcription factor IIF, polypeptide 2b
chr24_+_35881124 0.17 ENSDART00000143015
klhl14
kelch-like family member 14
chr6_-_19042294 0.16 ENSDART00000159461
si:rp71-81e14.2
si:rp71-81e14.2
chr7_+_59677273 0.16 ENSDART00000039535
ENSDART00000132044
trmt44
tRNA methyltransferase 44 homolog
chr15_-_37719015 0.16 ENSDART00000154875
si:dkey-117a8.1
si:dkey-117a8.1
chr16_+_20161805 0.15 ENSDART00000192146
c16h2orf66
chromosome 16 C2orf66 homolog
chr3_+_2719243 0.15 ENSDART00000189256
CR388047.3

chr4_+_77943184 0.14 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr5_-_29512538 0.14 ENSDART00000098364
ehmt1a
euchromatic histone-lysine N-methyltransferase 1a
chr4_-_9891874 0.14 ENSDART00000067193
adm2a
adrenomedullin 2a
chr8_-_17822259 0.13 ENSDART00000063587
st6galnac5b
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5b
chr21_+_6751405 0.13 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr20_+_28803977 0.12 ENSDART00000153351
ENSDART00000038149
fntb
farnesyltransferase, CAAX box, beta
chr11_+_31864921 0.12 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr10_-_40416054 0.12 ENSDART00000137947
ENSDART00000143606
taar20j
trace amine associated receptor 20j
chr4_-_20292821 0.12 ENSDART00000136069
ENSDART00000192504
cacna2d4a
calcium channel, voltage-dependent, alpha 2/delta subunit 4a
chr8_-_7567815 0.12 ENSDART00000132536
hcfc1b
host cell factor C1b
chr9_+_12444494 0.11 ENSDART00000102430
tmem41aa
transmembrane protein 41aa
chr4_+_62576422 0.11 ENSDART00000180679
si:ch211-79g12.2
si:ch211-79g12.2
chr20_-_51831816 0.11 ENSDART00000060505
mia3
melanoma inhibitory activity family, member 3
chr13_+_27328098 0.11 ENSDART00000037585
mb21d1
Mab-21 domain containing 1
chr25_+_6471401 0.10 ENSDART00000132927
snx33
sorting nexin 33
chr17_-_6618574 0.09 ENSDART00000184486
si:ch211-189e2.3
si:ch211-189e2.3
chr17_-_41081806 0.08 ENSDART00000030622
rbks
ribokinase
chr18_-_16801033 0.08 ENSDART00000100100
admb
adrenomedullin b
chr18_+_44630415 0.08 ENSDART00000098540
bicra
BRD4 interacting chromatin remodeling complex associated protein
chr22_-_21150845 0.08 ENSDART00000027345
tmem59l
transmembrane protein 59-like
chr5_+_872299 0.07 ENSDART00000130042
fubp3
far upstream element (FUSE) binding protein 3
chr16_+_35595312 0.06 ENSDART00000170438
si:ch211-1i11.3
si:ch211-1i11.3
chr16_+_9713850 0.05 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr25_-_27564205 0.04 ENSDART00000157319
hyal4
hyaluronoglucosaminidase 4
chr25_+_34748860 0.04 ENSDART00000087364
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr8_-_27656765 0.03 ENSDART00000078491
mov10b.2
Moloney leukemia virus 10b, tandem duplicate 2
chr15_-_42039192 0.03 ENSDART00000004338
epha4l
eph receptor A4, like
chr18_+_43891051 0.03 ENSDART00000024213
cxcr5
chemokine (C-X-C motif) receptor 5
chr22_+_2769236 0.03 ENSDART00000141836
si:dkey-20i20.10
si:dkey-20i20.10
chr12_+_3078221 0.02 ENSDART00000148835
ENSDART00000149427
sgca
sarcoglycan, alpha
chr13_+_22476742 0.02 ENSDART00000078759
ENSDART00000130101
ENSDART00000137220
ENSDART00000133065
ENSDART00000147348
ldb3a
LIM domain binding 3a
chr16_+_5774977 0.02 ENSDART00000134202
ccka
cholecystokinin a
chr2_+_10771787 0.01 ENSDART00000187782
gfi1aa
growth factor independent 1A transcription repressor a

Network of associatons between targets according to the STRING database.

First level regulatory network of msx1b+msx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 0.8 GO:0019532 oxalate transport(GO:0019532)
0.2 0.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 0.9 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.7 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.9 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.1 0.3 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.1 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.4 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.2 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.2 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.0 GO:0014823 response to activity(GO:0014823)
0.0 0.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279) post-translational protein modification(GO:0043687)
0.0 0.7 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 1.0 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.2 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.9 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.1 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 1.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.0 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 1.3 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097189 apoptotic body(GO:0097189)
0.2 1.2 GO:0035060 brahma complex(GO:0035060)
0.2 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.7 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.9 GO:0070847 core mediator complex(GO:0070847)
0.1 0.9 GO:0070552 BRISC complex(GO:0070552)
0.1 1.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 1.1 GO:0046930 pore complex(GO:0046930)
0.0 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0048030 disaccharide binding(GO:0048030)
0.2 0.8 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 0.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.7 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 2.6 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0032190 acrosin binding(GO:0032190)
0.1 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.9 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.9 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) FMN binding(GO:0010181) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.0 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.0 2.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides