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PRJEB1986: zebrafish developmental stages transcriptome

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Results for msx2b

Z-value: 0.42

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Transcription factors associated with msx2b

Gene Symbol Gene ID Gene Info
msx2b
ENSDARG00000101023 muscle segment homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx2bdr11_v1_chr21_-_41147818_41147818-0.493.4e-02Click!

Activity profile of msx2b motif

Sorted Z-values of msx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_11385155 1.67 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr3_+_36366577 1.28 ENSDART00000151203
rgs9a
regulator of G protein signaling 9a
chr17_-_6730247 1.12 ENSDART00000031091
vsnl1b
visinin-like 1b
chr15_-_34408777 1.04 ENSDART00000139934
agmo
alkylglycerol monooxygenase
chr10_+_25726694 1.02 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr20_+_35484070 0.95 ENSDART00000026234
ENSDART00000141675
mep1a.2
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2
chr13_+_23988442 0.92 ENSDART00000010918
agt
angiotensinogen
chr6_-_46861676 0.86 ENSDART00000188712
ENSDART00000190148
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr23_+_40460333 0.76 ENSDART00000184658
soga3b
SOGA family member 3b
chr19_-_47527093 0.74 ENSDART00000171379
ENSDART00000171140
ENSDART00000114886
scg5
secretogranin V
chr22_+_17203752 0.69 ENSDART00000143376
rab3b
RAB3B, member RAS oncogene family
chr1_+_42225060 0.68 ENSDART00000138740
ENSDART00000101306
ctnna2
catenin (cadherin-associated protein), alpha 2
chr13_+_8958438 0.64 ENSDART00000165721
ENSDART00000169398
haao
3-hydroxyanthranilate 3,4-dioxygenase
chr20_-_29474859 0.62 ENSDART00000152906
ENSDART00000045249
scg5
secretogranin V
chr1_+_11977426 0.61 ENSDART00000103399
tspan5b
tetraspanin 5b
chr8_+_40477264 0.60 ENSDART00000085559
gck
glucokinase (hexokinase 4)
chr17_-_200316 0.60 ENSDART00000190561
CABZ01083778.1

chr14_-_49063157 0.60 ENSDART00000021260
sept8b
septin 8b
chr23_-_24493768 0.60 ENSDART00000135559
ENSDART00000046933
sult1st5
sulfotransferase family 1, cytosolic sulfotransferase 5
chr24_-_14712427 0.60 ENSDART00000176316
jph1a
junctophilin 1a
chr12_+_28574863 0.58 ENSDART00000153284
tbkbp1
TBK1 binding protein 1
chr11_+_29770966 0.58 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr2_+_53357953 0.56 ENSDART00000187577
celf5b
cugbp, Elav-like family member 5b
chr13_+_2625150 0.56 ENSDART00000164177
plpp4
phospholipid phosphatase 4
chr1_+_34203817 0.55 ENSDART00000191432
ENSDART00000046094
arl6
ADP-ribosylation factor-like 6
chr6_-_30210378 0.54 ENSDART00000157359
ENSDART00000113924
lrrc7
leucine rich repeat containing 7
chr10_-_2522588 0.54 ENSDART00000081926
CU856539.1

chr17_+_31185276 0.52 ENSDART00000062887
disp2
dispatched homolog 2 (Drosophila)
chr7_+_65309738 0.50 ENSDART00000169228
vat1l
vesicle amine transport 1-like
chr7_+_69356661 0.47 ENSDART00000177049
CABZ01083862.1

chr20_+_4392687 0.47 ENSDART00000187271
im:7142702
im:7142702
chr8_-_44004135 0.46 ENSDART00000136269
rimbp2
RIMS binding protein 2
chr24_-_24849091 0.46 ENSDART00000133649
ENSDART00000038290
crhb
corticotropin releasing hormone b
chr17_-_51199558 0.46 ENSDART00000154532
paplna
papilin a, proteoglycan-like sulfated glycoprotein
chr20_-_53366137 0.44 ENSDART00000146001
wasf1
WAS protein family, member 1
chr21_-_39639954 0.44 ENSDART00000026766
aldocb
aldolase C, fructose-bisphosphate, b
chr25_+_5604512 0.44 ENSDART00000042781
plxnb2b
plexin b2b
chr21_+_21195487 0.43 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr2_-_23778180 0.43 ENSDART00000136782
si:dkey-24c2.7
si:dkey-24c2.7
chr3_+_22935183 0.42 ENSDART00000157378
hdac5
histone deacetylase 5
chr21_-_44009169 0.42 ENSDART00000028960
ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr15_+_19646902 0.42 ENSDART00000179822
lim2.3
lens intrinsic membrane protein 2.3
chr13_-_36050303 0.40 ENSDART00000134955
ENSDART00000139087
lgmn
legumain
chr8_+_22930627 0.40 ENSDART00000187860
sypa
synaptophysin a
chr23_+_13375359 0.39 ENSDART00000151947
ZNF512B
si:dkey-256k13.2
chr3_-_43821191 0.39 ENSDART00000186816
snn
stannin
chr18_+_10884996 0.38 ENSDART00000147613
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr16_+_13818500 0.38 ENSDART00000135245
flcn
folliculin
chr9_+_44721808 0.38 ENSDART00000190578
nckap1
NCK-associated protein 1
chr11_+_37178271 0.37 ENSDART00000161771
itih3b
inter-alpha-trypsin inhibitor heavy chain 3b
chr1_+_54137089 0.37 ENSDART00000062945
LO017798.1

chr7_-_24005268 0.37 ENSDART00000173608
si:dkey-183c6.9
si:dkey-183c6.9
chr11_-_28911172 0.37 ENSDART00000168493
igsf21a
immunoglobin superfamily, member 21a
chr4_+_14900042 0.37 ENSDART00000018261
akr1b1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr16_+_1353894 0.36 ENSDART00000148426
celf3b
cugbp, Elav-like family member 3b
chr15_-_19051152 0.36 ENSDART00000186453
arhgap32a
Rho GTPase activating protein 32a
chr3_-_34296361 0.34 ENSDART00000181485
ENSDART00000113726
tnrc6c1
trinucleotide repeat containing 6C1
chr10_-_41157135 0.34 ENSDART00000134851
aak1b
AP2 associated kinase 1b
chr1_-_55785722 0.32 ENSDART00000142069
ENSDART00000043933
ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr22_-_14739491 0.31 ENSDART00000133385
lrp1ba
low density lipoprotein receptor-related protein 1Ba
chr9_-_2572790 0.31 ENSDART00000135076
ENSDART00000016710
scrn3
secernin 3
chr5_+_65493699 0.31 ENSDART00000161567
si:dkey-21e5.1
si:dkey-21e5.1
chr22_-_15562933 0.31 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr6_-_55347616 0.30 ENSDART00000172081
pcif1
PDX1 C-terminal inhibiting factor 1
chr21_-_5205617 0.30 ENSDART00000145554
ENSDART00000045284
rpl37
ribosomal protein L37
chr8_+_3426522 0.30 ENSDART00000159466
CU929199.1

chr7_+_6990510 0.29 ENSDART00000138948
ccs
copper chaperone for superoxide dismutase
chr8_-_1838315 0.29 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr20_-_2134620 0.28 ENSDART00000064375
tmem244
transmembrane protein 244
chr23_-_35064785 0.28 ENSDART00000172240
BX294434.1

chr23_-_14990865 0.28 ENSDART00000147799
ndrg3b
ndrg family member 3b
chr12_+_10115964 0.27 ENSDART00000152369
si:dkeyp-118b1.2
si:dkeyp-118b1.2
chr16_+_41570653 0.26 ENSDART00000102665
aste1a
asteroid homolog 1a
chr13_+_23132666 0.26 ENSDART00000164639
sorbs1
sorbin and SH3 domain containing 1
chr9_+_20780813 0.26 ENSDART00000142787
fam46c
family with sequence similarity 46, member C
chr12_+_5081759 0.25 ENSDART00000164178
prrt2
proline-rich transmembrane protein 2
chr1_+_35194454 0.24 ENSDART00000165389
sc:d189
sc:d189
chr17_+_5915875 0.24 ENSDART00000184179
fndc4b
fibronectin type III domain containing 4b
chr13_+_50151407 0.24 ENSDART00000031858
gpr137ba
G protein-coupled receptor 137Ba
chr11_+_29856032 0.24 ENSDART00000079150
grpr
gastrin-releasing peptide receptor
chr8_-_26792912 0.24 ENSDART00000139787
kazna
kazrin, periplakin interacting protein a
chr23_-_44903048 0.23 ENSDART00000149103
fhdc5
FH2 domain containing 5
chr24_-_31843173 0.22 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr11_+_2687395 0.22 ENSDART00000082510
b3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr3_-_44059902 0.22 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr6_+_54239625 0.21 ENSDART00000149542
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr2_+_6127593 0.21 ENSDART00000184007
fzr1b
fizzy/cell division cycle 20 related 1b
chr6_-_15641686 0.21 ENSDART00000135583
mlpha
melanophilin a
chr22_+_30543437 0.20 ENSDART00000137983
si:dkey-103k4.1
si:dkey-103k4.1
chr22_-_18164835 0.19 ENSDART00000143189
rfxank
regulatory factor X-associated ankyrin-containing protein
chr23_-_41965557 0.19 ENSDART00000144183
slc1a7b
solute carrier family 1 (glutamate transporter), member 7b
chr19_+_20540843 0.19 ENSDART00000192500
kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr10_+_6013076 0.19 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr12_+_38929663 0.18 ENSDART00000156334
si:dkey-239b22.1
si:dkey-239b22.1
chr21_+_38002879 0.18 ENSDART00000065183
cldn2
claudin 2
chr4_+_78058635 0.18 ENSDART00000162631
ENSDART00000191619
CABZ01075274.1

chr23_-_32092443 0.17 ENSDART00000133688
letmd1
LETM1 domain containing 1
chr12_-_2993095 0.17 ENSDART00000152316
si:dkey-202c14.3
si:dkey-202c14.3
chr13_-_40238813 0.17 ENSDART00000044963
loxl4
lysyl oxidase-like 4
chr1_-_493218 0.17 ENSDART00000031635
ercc5
excision repair cross-complementation group 5
chr25_-_24248000 0.16 ENSDART00000073527
spty2d1
SPT2 chromatin protein domain containing 1
chr13_+_28747934 0.16 ENSDART00000160176
ENSDART00000101633
ENSDART00000136318
prom2
prominin 2
chr12_-_3992839 0.16 ENSDART00000126100
si:ch211-136m16.8
si:ch211-136m16.8
chr14_-_12307522 0.16 ENSDART00000163900
myot
myotilin
chr21_-_35082715 0.16 ENSDART00000146454
adrb2b
adrenoceptor beta 2, surface b
chr23_-_27692717 0.15 ENSDART00000053878
ENSDART00000145028
IKZF4
si:dkey-166n8.9
chr24_-_3783497 0.15 ENSDART00000158354
adarb2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr19_+_2279051 0.15 ENSDART00000182103
itgb8
integrin, beta 8
chr15_-_4094888 0.15 ENSDART00000166307
TM4SF19
si:dkey-83h2.3
chr14_-_899170 0.14 ENSDART00000165211
ENSDART00000031992
rgs14a
regulator of G protein signaling 14a
chr14_+_23874062 0.14 ENSDART00000172149
sh3rf2
SH3 domain containing ring finger 2
chr7_+_33145529 0.14 ENSDART00000052387
itln2
intelectin 2
chr2_+_42871831 0.14 ENSDART00000171393
efr3a
EFR3 homolog A (S. cerevisiae)
chr1_+_12068800 0.14 ENSDART00000055566
xpa
xeroderma pigmentosum, complementation group A
chr14_-_16379843 0.13 ENSDART00000090711
ltc4s
leukotriene C4 synthase
chr11_+_44804685 0.13 ENSDART00000163660
strn
striatin, calmodulin binding protein
chr20_+_38031439 0.13 ENSDART00000153208
galnt14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr22_-_547748 0.13 ENSDART00000037455
ENSDART00000140101
ccnd3
cyclin D3
chr18_-_7539469 0.13 ENSDART00000101296
si:dkey-30c15.2
si:dkey-30c15.2
chr14_+_1007169 0.12 ENSDART00000172676
f8
coagulation factor VIII, procoagulant component
chr5_+_24882633 0.12 ENSDART00000111302
rhbdd3
rhomboid domain containing 3
chr15_+_5339056 0.11 ENSDART00000174319
CABZ01018874.2

chr19_+_22727940 0.11 ENSDART00000052509
trhrb
thyrotropin-releasing hormone receptor b
chr14_-_3132188 0.10 ENSDART00000172259
si:zfos-1069f5.1
si:zfos-1069f5.1
chr22_+_1887750 0.10 ENSDART00000180917
si:dkey-15h8.17
si:dkey-15h8.17
chr22_+_31295791 0.10 ENSDART00000092447
grip2b
glutamate receptor interacting protein 2b
chr5_+_1983495 0.10 ENSDART00000179860
CT573103.2

chr11_+_3254524 0.10 ENSDART00000159459
pmela
premelanosome protein a
chr3_-_13461361 0.10 ENSDART00000080807
fbxw9
F-box and WD repeat domain containing 9
chr9_+_41156818 0.10 ENSDART00000105764
ENSDART00000147052
stat4
signal transducer and activator of transcription 4
chr5_+_13427826 0.10 ENSDART00000083359
sec14l8
SEC14-like lipid binding 8
chr13_-_4018888 0.09 ENSDART00000058238
tjap1
tight junction associated protein 1 (peripheral)
chr3_+_18398876 0.09 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr15_-_5252673 0.09 ENSDART00000132963
or126-1
odorant receptor, family E, subfamily 126, member 1
chr19_-_3255725 0.08 ENSDART00000105165
illr1
immune-related, lectin-like receptor 1
chr16_-_50897887 0.08 ENSDART00000156985
si:ch73-90p23.1
si:ch73-90p23.1
chr22_+_28818291 0.07 ENSDART00000136032
tp53bp2b
tumor protein p53 binding protein, 2b
chr10_-_16065185 0.07 ENSDART00000187266
si:dkey-184a18.5
si:dkey-184a18.5
chr25_-_28926631 0.07 ENSDART00000112850
etfbkmt
electron transfer flavoprotein beta subunit lysine methyltransferase
chr25_+_10909850 0.07 ENSDART00000186021
CR339041.3

chr10_-_26430168 0.07 ENSDART00000128894
dchs1b
dachsous cadherin-related 1b
chr14_+_23520986 0.07 ENSDART00000170473
ENSDART00000175970
si:ch211-221f10.2
si:ch211-221f10.2
chr22_-_16755885 0.07 ENSDART00000036467
patj
PATJ, crumbs cell polarity complex component
chr10_-_5016997 0.06 ENSDART00000101414
hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr24_-_26328721 0.06 ENSDART00000125468
apodb
apolipoprotein Db
chr5_-_36674139 0.06 ENSDART00000188100
BX005407.1

chr10_+_9697097 0.06 ENSDART00000167821
rabgap1
RAB GTPase activating protein 1
chr11_-_45152702 0.06 ENSDART00000168066
afmid
arylformamidase
chr15_-_19669770 0.06 ENSDART00000152707
si:dkey-4p15.3
si:dkey-4p15.3
chr3_-_33427803 0.06 ENSDART00000075495
rpl23
ribosomal protein L23
chr23_-_27015160 0.05 ENSDART00000189028
CU862020.1

chr5_-_66768121 0.05 ENSDART00000141095
FERMT3 (1 of many)
im:7154036
chr3_+_25195966 0.05 ENSDART00000112338
il2rb
interleukin 2 receptor, beta
chr22_-_18164671 0.04 ENSDART00000014057
rfxank
regulatory factor X-associated ankyrin-containing protein
chr7_-_59210882 0.04 ENSDART00000170330
ENSDART00000158996
nagk
N-acetylglucosamine kinase
chr15_-_28082310 0.03 ENSDART00000152620
dhrs13a.3
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr25_+_31405266 0.03 ENSDART00000103395
tnnt3a
troponin T type 3a (skeletal, fast)
chr10_+_20392083 0.03 ENSDART00000166867
r3hcc1
R3H domain and coiled-coil containing 1
chr3_-_39305291 0.03 ENSDART00000102674
plcd3a
phospholipase C, delta 3a
chr10_+_8690936 0.02 ENSDART00000144218
si:dkey-27b3.4
si:dkey-27b3.4
chr15_+_2190229 0.02 ENSDART00000147710
rsrc1
arginine/serine-rich coiled-coil 1
chr4_-_5455506 0.02 ENSDART00000156593
ENSDART00000154676
si:dkey-14d8.22
si:dkey-14d8.22
chr3_-_31619463 0.01 ENSDART00000124559
moto
minamoto
chr25_-_18953322 0.01 ENSDART00000155927
si:ch211-68a17.7
si:ch211-68a17.7
chr10_-_18463934 0.01 ENSDART00000133116
ENSDART00000113422
si:dkey-28o19.1
si:dkey-28o19.1
chr21_+_19062124 0.01 ENSDART00000134746
rpl17
ribosomal protein L17
chr20_+_36628059 0.01 ENSDART00000062898
ephx1
epoxide hydrolase 1, microsomal (xenobiotic)
chr18_+_7073130 0.01 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr16_-_21917361 0.00 ENSDART00000171818
setdb1b
SET domain, bifurcated 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of msx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 0.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.6 GO:0043420 anthranilate metabolic process(GO:0043420)
0.1 0.4 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 0.2 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.2 GO:0015677 copper ion import(GO:0015677)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.2 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.9 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0 0.1 GO:1901255 UV-damage excision repair(GO:0070914) nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.0 0.3 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 1.4 GO:0046883 regulation of hormone secretion(GO:0046883)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.4 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0071451 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.1 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.4 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.0 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0034354 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0071914 prominosome(GO:0071914)
0.0 1.4 GO:0031514 motile cilium(GO:0031514)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.6 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.3 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.6 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 1.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis