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PRJEB1986: zebrafish developmental stages transcriptome

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Results for myb+mybl1

Z-value: 1.54

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Transcription factors associated with myb+mybl1

Gene Symbol Gene ID Gene Info
ENSDARG00000030999 v-myb avian myeloblastosis viral oncogene homolog-like 1
ENSDARG00000053666 v-myb avian myeloblastosis viral oncogene homolog
ENSDARG00000114024 v-myb avian myeloblastosis viral oncogene homolog

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mybdr11_v1_chr23_+_31815423_318154920.954.3e-10Click!
mybl1dr11_v1_chr24_+_23791758_237918390.427.1e-02Click!

Activity profile of myb+mybl1 motif

Sorted Z-values of myb+mybl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_25935167 4.93 ENSDART00000139855
GTPase activating protein (SH3 domain) binding protein 1
chr3_+_27027781 3.96 ENSDART00000065495
epithelial membrane protein 2
chr10_-_35257458 3.87 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr6_-_36552844 3.36 ENSDART00000023613
hairy-related 6
chr6_+_40832635 3.26 ENSDART00000011931
RuvB-like AAA ATPase 1
chr1_-_53684005 3.24 ENSDART00000108906
exportin 1 (CRM1 homolog, yeast) a
chr3_+_23737795 3.05 ENSDART00000182247
homeobox B3a
chr3_+_41922114 2.93 ENSDART00000138280
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_-_33121535 2.74 ENSDART00000166371
ENSDART00000138052
zgc:172014
chr16_-_27566552 2.63 ENSDART00000142102
zgc:153215
chr20_+_47434709 2.61 ENSDART00000067776
RAB10, member RAS oncogene family
chr6_-_50685862 2.58 ENSDART00000134146
metastasis suppressor 1
chr24_-_37003577 2.58 ENSDART00000137777
dynein, axonemal, assembly factor 3
chr7_+_22809905 2.57 ENSDART00000166900
ENSDART00000143455
ENSDART00000126037
splicing factor 1
chr14_-_246342 2.54 ENSDART00000054823
aurora kinase B
chr6_-_9630081 2.52 ENSDART00000013066
excision repair cross-complementation group 3
chr5_+_25304499 2.49 ENSDART00000163425
carnosine N-methyltransferase 1
chr3_+_43086548 2.48 ENSDART00000163579
si:dkey-43p13.5
chr21_-_28901095 2.31 ENSDART00000180820
CXXC finger protein 5a
chr7_+_24393678 2.30 ENSDART00000188690
HAUS augmin-like complex, subunit 3
chr24_-_13272842 2.27 ENSDART00000146790
ENSDART00000066703
retinol dehydrogenase 10a
chr25_-_16666886 2.23 ENSDART00000155764
solute carrier family 25 (glutamate carrier), member 18
chr4_-_52165969 2.21 ENSDART00000171130
si:dkeyp-44b5.4
chr14_+_21828993 2.13 ENSDART00000144367
C-terminal binding protein 1
chr8_+_14381272 2.12 ENSDART00000057642
acyl-CoA binding domain containing 6
chr2_+_56012016 2.11 ENSDART00000146160
ENSDART00000188702
lysyl oxidase-like 5b
chr5_-_61624693 2.06 ENSDART00000141323
si:dkey-261j4.4
chr1_-_18585046 2.06 ENSDART00000147228
family with sequence similarity 114, member A1
chr1_+_604127 2.04 ENSDART00000133165
junctional adhesion molecule 2a
chr18_-_15551360 2.04 ENSDART00000159915
ENSDART00000172690
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr5_-_61638125 2.03 ENSDART00000134314
si:dkey-261j4.3
chr22_-_25612680 2.03 ENSDART00000114167
si:ch211-12h2.8
chr23_+_32029304 2.01 ENSDART00000185217
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr5_-_39805874 2.00 ENSDART00000176202
ENSDART00000191683
RasGEF domain family, member 1Ba
chr5_-_66749535 1.98 ENSDART00000132183
K(lysine) acetyltransferase 5b
chr20_-_20930926 1.98 ENSDART00000123909
BTB (POZ) domain containing 6b
chr17_+_49637257 1.93 ENSDART00000075281
ENSDART00000065917
ENSDART00000123641
zgc:113372
chr7_+_24006875 1.92 ENSDART00000033755
homeobox and leucine zipper encoding b
chr3_-_40275096 1.90 ENSDART00000141578
serine hydroxymethyltransferase 1 (soluble)
chr16_+_48616220 1.89 ENSDART00000004751
ENSDART00000130045
pre-B-cell leukemia homeobox 2
chr22_-_12763350 1.88 ENSDART00000143574
CCR4-NOT transcription complex subunit 9
chr19_+_10831362 1.88 ENSDART00000053325
translocase of outer mitochondrial membrane 40 homolog, like
chr15_-_35224173 1.86 ENSDART00000014415
mitochondrial ribosomal protein L44
chr2_+_30481125 1.86 ENSDART00000125933
family with sequence similarity 173, member B
chr13_+_48359573 1.83 ENSDART00000161959
ENSDART00000165311
mutS homolog 6 (E. coli)
chr8_-_14609284 1.82 ENSDART00000146175
centrosomal protein 350
chr1_+_51537250 1.82 ENSDART00000152789
ETAA1, ATR kinase activator
chr16_-_29164379 1.81 ENSDART00000132589
myocyte enhancer factor 2d
chr4_-_78026285 1.80 ENSDART00000168273
chaperonin containing TCP1 subunit 2
chr11_-_36263886 1.79 ENSDART00000140397
nuclear transcription factor Y, alpha
chr25_-_37262220 1.79 ENSDART00000153789
ENSDART00000155182
ring finger and WD repeat domain 3
chr19_-_35450661 1.77 ENSDART00000113574
ENSDART00000136895
anillin, actin binding protein
chr8_+_29749017 1.77 ENSDART00000185144
mitogen-activated protein kinase 4
chr6_-_33916756 1.77 ENSDART00000137447
ENSDART00000138488
nuclear autoantigenic sperm protein (histone-binding)
chr22_+_413349 1.77 ENSDART00000082453
cadherin, EGF LAG seven-pass G-type receptor 2
chr13_+_26703922 1.76 ENSDART00000020946
Fanconi anemia, complementation group L
chr19_-_1002959 1.73 ENSDART00000168138
euchromatic histone-lysine N-methyltransferase 2
chr22_-_6499055 1.73 ENSDART00000142235
ENSDART00000183588
si:dkey-19a16.7
chr5_-_32424402 1.72 ENSDART00000077549
neuronal calcium sensor 1a
chr19_+_10661520 1.69 ENSDART00000091813
ENSDART00000165653
argonaute RISC catalytic component 3b
chr14_-_30905288 1.68 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
chr21_-_21526740 1.67 ENSDART00000142690
diablo, IAP-binding mitochondrial protein b
chr5_+_32932357 1.67 ENSDART00000192397
LIM domain only 4a
chr13_+_1131748 1.67 ENSDART00000054318
WD repeat domain 92
chr3_+_23738215 1.67 ENSDART00000143981
homeobox B3a
chr3_-_37082618 1.66 ENSDART00000026701
ENSDART00000110716
tubulin, gamma 1
chr11_+_13176568 1.66 ENSDART00000125371
ENSDART00000123257
MAP kinase interacting serine/threonine kinase 1
chr13_+_21870269 1.66 ENSDART00000144612
zinc finger, SWIM-type containing 8
chr19_-_35450857 1.65 ENSDART00000179357
anillin, actin binding protein
chr1_-_8140763 1.65 ENSDART00000091508
si:dkeyp-9d4.4
chr8_-_14080534 1.63 ENSDART00000042867
death effector domain containing
chr25_-_20381271 1.63 ENSDART00000142665
potassium channel tetramerization domain containing 15a
chr18_-_16924221 1.62 ENSDART00000122102
WEE1 G2 checkpoint kinase
chr10_-_22797959 1.59 ENSDART00000183269
procollagen C-endopeptidase enhancer a
chr7_-_49646251 1.59 ENSDART00000193674
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr8_+_23034718 1.59 ENSDART00000184512
YTH N(6)-methyladenosine RNA binding protein 1
chr10_+_35257651 1.58 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr22_+_10232527 1.58 ENSDART00000139297
si:dkeyp-87e7.4
chr6_+_33931740 1.57 ENSDART00000130492
ENSDART00000151213
origin recognition complex, subunit 1
chr17_+_23968214 1.56 ENSDART00000183053
exportin 1 (CRM1 homolog, yeast) b
chr21_-_929293 1.55 ENSDART00000006419
thioredoxin-like 1
chr11_-_309420 1.54 ENSDART00000173185
POC1 centriolar protein A
chr6_+_13201358 1.54 ENSDART00000190290

chr16_+_53125918 1.53 ENSDART00000102170

chr23_+_36616717 1.53 ENSDART00000042701
ENSDART00000192980
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr8_-_50259448 1.53 ENSDART00000146056
NK3 homeobox 1
chr8_+_23639124 1.52 ENSDART00000083108
5'-nucleotidase domain containing 2
chr16_-_40459104 1.51 ENSDART00000032389
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr21_-_31013817 1.51 ENSDART00000065504
nuclear cap binding subunit 3
chr7_+_41340520 1.50 ENSDART00000005127
GRB2 associated, regulator of MAPK1
chr17_-_22573311 1.49 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exonuclease 1
chr3_+_31717291 1.47 ENSDART00000058221
ddb1 and cul4 associated factor 7
chr4_+_27100531 1.47 ENSDART00000115200
ALG12, alpha-1,6-mannosyltransferase
chr6_-_22369125 1.46 ENSDART00000083038
NPR2 like, GATOR1 complex subunit
chr15_+_36977208 1.45 ENSDART00000183625
kirre like nephrin family adhesion molecule 3, like
chr21_-_13668358 1.45 ENSDART00000180323
patatin-like phospholipase domain containing 7a
chr11_+_14622379 1.43 ENSDART00000112589
ephrin-A2b
chr2_-_59145027 1.43 ENSDART00000128320

chr17_-_45734231 1.42 ENSDART00000074873
ADP-ribosylation factor 6b
chr6_-_39518489 1.42 ENSDART00000185446
activating transcription factor 1
chr11_+_24816238 1.42 ENSDART00000115356
RAB interacting factor
chr1_+_27808916 1.42 ENSDART00000102335
paraspeckle component 1
chr5_+_36895860 1.41 ENSDART00000134493
serine/arginine-rich splicing factor 7a
chr4_+_13568469 1.40 ENSDART00000171235
ENSDART00000136152
calumenin a
chr1_+_41596099 1.40 ENSDART00000111367
si:dkey-56e3.3
chr14_-_15155384 1.40 ENSDART00000172666
UV-stimulated scaffold protein A
chr5_-_36597612 1.39 ENSDART00000031270
ENSDART00000122098
ras homolog gene family, member Gc
chr11_+_24815927 1.39 ENSDART00000146838
RAB interacting factor
chr1_-_53880639 1.37 ENSDART00000010543
LTV1 ribosome biogenesis factor
chr11_+_2642013 1.37 ENSDART00000111324
zgc:193807
chr11_-_25461336 1.37 ENSDART00000014945
host cell factor C1a
chr18_-_16937008 1.36 ENSDART00000100117
ENSDART00000022640
ENSDART00000136541
zinc finger protein 143b
chr3_-_26921475 1.36 ENSDART00000130281
class II, major histocompatibility complex, transactivator
chr10_-_35248502 1.35 ENSDART00000087477
SMG8 nonsense mediated mRNA decay factor
chr8_+_47683539 1.33 ENSDART00000190701
dipeptidyl-peptidase 9
chr9_+_24095677 1.33 ENSDART00000150443
leucine rich repeat (in FLII) interacting protein 1a
chr22_-_22259175 1.32 ENSDART00000113824
HDGF like 2
chr22_+_15973122 1.32 ENSDART00000144545
ring finger and CCCH-type domains 1a
chr3_+_53156813 1.31 ENSDART00000114343
bromodomain containing 4
chr23_-_9855627 1.31 ENSDART00000180159
protein kinase C binding protein 1, like
chr7_-_34265481 1.31 ENSDART00000173596
si:ch211-98n17.5
chr13_-_5257303 1.30 ENSDART00000110610
si:dkey-78p8.1
chr18_-_2668698 1.29 ENSDART00000157510
RELT, TNF receptor
chr24_+_21174851 1.28 ENSDART00000154940
ENSDART00000155977
ENSDART00000122762
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr15_+_15786160 1.27 ENSDART00000130670
ENSDART00000090939
transcriptional adaptor 2A
chr18_+_7639401 1.27 ENSDART00000092416
RAB, member of RAS oncogene family-like 2
chr13_-_11986754 1.27 ENSDART00000164214
nucleophosmin/nucleoplasmin, 3
chr24_+_4978055 1.26 ENSDART00000045813
zic family member 4
chr21_-_39024754 1.26 ENSDART00000056878
tnf receptor-associated factor 4b
chr21_+_39963851 1.25 ENSDART00000144435
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr21_+_21611867 1.24 ENSDART00000189148
B9 domain containing 2
chr24_+_21174523 1.22 ENSDART00000183849
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr20_-_15099579 1.22 ENSDART00000127213
flavin containing monooxygenase 5
chr22_-_10158038 1.20 ENSDART00000047444
RanBP-type and C3HC4-type zinc finger containing 1
chr23_+_4348479 1.20 ENSDART00000182425
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr6_-_33931696 1.19 ENSDART00000057290
pre-mRNA processing factor 38A
chr4_-_36791395 1.19 ENSDART00000162654
si:dkeyp-87d1.1
chr5_+_51833132 1.19 ENSDART00000167491
PAP associated domain containing 4
chr20_-_18794789 1.18 ENSDART00000003834
cerebral cavernous malformation 2
chr16_-_11986321 1.18 ENSDART00000148666
ENSDART00000029121
ubiquitin specific peptidase 5 (isopeptidase T)
chr22_+_4447387 1.18 ENSDART00000189742
ENSDART00000166768
translocase of inner mitochondrial membrane 44 homolog (yeast)
chr16_+_38159758 1.18 ENSDART00000058666
ENSDART00000112165
phosphatidylinositol 4-kinase, catalytic, beta
chr20_+_33744065 1.18 ENSDART00000015000
HEN methyltransferase 1
chr13_+_18311410 1.18 ENSDART00000036718
ENSDART00000132073
eukaryotic translation initiation factor 4E family member 1c
chr16_-_39267185 1.17 ENSDART00000058550
ENSDART00000133642
glycerol-3-phosphate dehydrogenase 1 like
chr3_-_1520657 1.17 ENSDART00000053201
polymerase (RNA) II (DNA directed) polypeptide F
chr19_-_5699703 1.16 ENSDART00000082050
zgc:174904
chr23_-_21215520 1.15 ENSDART00000143206
multiple EGF-like-domains 6a
chr15_-_23721618 1.14 ENSDART00000109318
zinc finger CCCH-type containing 4
chr14_+_6535426 1.13 ENSDART00000055961
tRNA-histidine guanylyltransferase 1-like
chr5_-_69548986 1.13 ENSDART00000097250
ENSDART00000163390
ENSDART00000166117
ENSDART00000167625
ENSDART00000191777
KISS1 receptor b
chr9_-_33877476 1.12 ENSDART00000150035
ENSDART00000088441
ENSDART00000183210
si:ch73-147f11.1
chr15_-_26887028 1.11 ENSDART00000156292
si:dkey-243i1.1
chr16_+_10422836 1.09 ENSDART00000161568
INO80 complex subunit E
chr3_-_31715714 1.08 ENSDART00000051542
coiled-coil domain containing 47
chr6_-_6976096 1.08 ENSDART00000151822
ENSDART00000039443
ENSDART00000177960
tubulin, alpha 8 like 4
chr12_+_11650146 1.07 ENSDART00000150191
WAPL cohesin release factor b
chr17_-_31579715 1.07 ENSDART00000110167
ENSDART00000191092
RNA polymerase II associated protein 1
chr21_-_226071 1.07 ENSDART00000160667
nucleoporin 54
chr11_+_16152316 1.07 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr24_-_4973765 1.07 ENSDART00000127597
zic family member 1 (odd-paired homolog, Drosophila)
chr19_+_2602903 1.07 ENSDART00000033132
family with sequence similarity 126, member A
chr17_-_33716688 1.06 ENSDART00000043651
dynein, axonemal, light chain 1
chr11_-_16152400 1.05 ENSDART00000123665
actin related protein 2/3 complex, subunit 4, like
chr7_+_53755054 1.05 ENSDART00000181629
neogenin 1a
chr6_-_32087108 1.05 ENSDART00000150934
ENSDART00000130627
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)
chr24_+_33392698 1.04 ENSDART00000122579
si:ch73-173p19.1
chr17_+_21818093 1.04 ENSDART00000125335
IKAROS family zinc finger 5
chr2_-_24317240 1.03 ENSDART00000078975
tRNA selenocysteine 1 associated protein 1b
chr25_+_1732838 1.03 ENSDART00000159555
ENSDART00000168161
fibulin 1
chr14_-_16423200 1.03 ENSDART00000108868
ENSDART00000161793
mastermind-like transcriptional coactivator 1
chr7_+_53754653 1.02 ENSDART00000163261
ENSDART00000158160
neogenin 1a
chr14_-_7409364 1.00 ENSDART00000036463
DND microRNA-mediated repression inhibitor 1
chr18_-_15532016 1.00 ENSDART00000165279
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr13_+_18471546 1.00 ENSDART00000090712
ENSDART00000127962
storkhead box 1
chr15_-_35224481 0.99 ENSDART00000099600
mitochondrial ribosomal protein L44
chr19_-_27827744 0.99 ENSDART00000181620
PAP associated domain containing 7
chr22_-_38224315 0.98 ENSDART00000165430
ENSDART00000140968
Hermansky-Pudlak syndrome 3
chr11_+_24816516 0.98 ENSDART00000142327
RAB interacting factor
chr5_+_51833305 0.98 ENSDART00000165276
ENSDART00000166443
PAP associated domain containing 4
chr23_+_4348265 0.98 ENSDART00000136287
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr4_+_77709678 0.97 ENSDART00000036856

chr13_+_1132261 0.97 ENSDART00000146049
WD repeat domain 92
chr18_-_5248365 0.97 ENSDART00000082506
ENSDART00000082504
ENSDART00000097960
myelin expression factor 2
chr19_-_10810006 0.97 ENSDART00000151157
si:dkey-3n22.9
chr24_-_41180149 0.96 ENSDART00000019975
activin A receptor type 2Ba
chr18_-_29972709 0.95 ENSDART00000131207
si:ch211-220f16.2
chr14_+_34514336 0.95 ENSDART00000024440
forkhead box I3b
chr25_-_34740627 0.95 ENSDART00000137665
fibroblast growth factor receptor substrate 2b
chr23_-_21215311 0.94 ENSDART00000112424
multiple EGF-like-domains 6a
chr7_-_17712665 0.94 ENSDART00000149047
multiple endocrine neoplasia I
chr21_+_21612214 0.94 ENSDART00000008099
B9 domain containing 2
chr15_+_436776 0.93 ENSDART00000008504
mediator complex subunit 17
chr19_-_3240605 0.93 ENSDART00000105168
si:ch211-133n4.4
chr1_-_59411901 0.93 ENSDART00000167015
si:ch211-188p14.4
chr18_+_46151505 0.92 ENSDART00000015034
ENSDART00000141287
biliverdin reductase B
chr17_-_25649079 0.92 ENSDART00000130955
protein phosphatase 1, catalytic subunit, beta isozyme
chr15_+_21672700 0.92 ENSDART00000187043
si:dkey-40g16.5
chr10_-_6588793 0.92 ENSDART00000163788
chromodomain helicase DNA binding protein 1
chr19_-_25149598 0.90 ENSDART00000162917
protein tyrosine phosphatase type IVA, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of myb+mybl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0003071 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.9 2.8 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.9 3.4 GO:0008356 asymmetric cell division(GO:0008356)
0.7 3.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.7 6.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.6 1.9 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.6 2.5 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.6 1.8 GO:0006290 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.6 4.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.6 3.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.6 1.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.5 2.9 GO:0055016 hypochord development(GO:0055016)
0.5 3.3 GO:0000492 box C/D snoRNP assembly(GO:0000492) regulation of heart growth(GO:0060420)
0.4 2.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.4 1.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 1.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.4 1.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4 1.9 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.4 3.4 GO:0021794 thalamus development(GO:0021794)
0.4 1.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.4 1.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.3 2.3 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.3 1.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.3 1.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.3 0.9 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 1.2 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.3 1.7 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.3 2.2 GO:0036372 opsin transport(GO:0036372)
0.3 2.6 GO:0044458 motile cilium assembly(GO:0044458)
0.3 2.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 1.0 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.2 1.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 1.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 0.7 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.2 0.7 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 2.2 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 1.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.6 GO:0016246 RNA interference(GO:0016246)
0.2 1.1 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.2 0.9 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.2 2.3 GO:0042572 retinol metabolic process(GO:0042572)
0.2 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.2 3.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 1.7 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.2 0.7 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.2 1.0 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.2 1.3 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.2 1.8 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.1 4.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 2.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 1.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.8 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 1.8 GO:0021754 facial nucleus development(GO:0021754)
0.1 3.5 GO:0007520 myoblast fusion(GO:0007520)
0.1 2.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.5 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.7 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 1.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 1.8 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.9 GO:0010522 regulation of calcium ion transport into cytosol(GO:0010522) regulation of release of sequestered calcium ion into cytosol(GO:0051279)
0.1 0.4 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.1 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.9 GO:0006298 mismatch repair(GO:0006298)
0.1 3.9 GO:0007050 cell cycle arrest(GO:0007050)
0.1 2.9 GO:0060872 semicircular canal development(GO:0060872)
0.1 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.5 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 1.9 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 2.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.4 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 2.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 2.0 GO:0060037 pharyngeal system development(GO:0060037)
0.1 1.0 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 2.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 1.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:0003272 endocardial cushion morphogenesis(GO:0003203) endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.0 1.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.3 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 3.4 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 1.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 3.9 GO:0016573 histone acetylation(GO:0016573)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 2.5 GO:0048484 enteric nervous system development(GO:0048484)
0.0 2.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.3 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 2.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 2.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.8 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.3 GO:0044319 wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505) skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0044058 regulation of digestive system process(GO:0044058)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.3 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.0 1.5 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 1.6 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.8 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.6 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 2.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.7 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.5 GO:0001878 response to yeast(GO:0001878)
0.0 0.5 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.2 GO:0001570 vasculogenesis(GO:0001570)
0.0 3.7 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 2.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.0 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.4 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.5 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.9 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 1.2 GO:1904888 cranial skeletal system development(GO:1904888)
0.0 1.0 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 1.1 GO:0006400 tRNA modification(GO:0006400)
0.0 3.0 GO:0007009 plasma membrane organization(GO:0007009)
0.0 1.7 GO:0030900 forebrain development(GO:0030900)
0.0 0.8 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.2 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0097255 R2TP complex(GO:0097255)
0.6 1.8 GO:0032301 MutSalpha complex(GO:0032301)
0.5 2.0 GO:0005880 nuclear microtubule(GO:0005880)
0.5 2.5 GO:0031415 NatA complex(GO:0031415)
0.5 3.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 2.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.3 2.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 2.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 2.3 GO:0070652 HAUS complex(GO:0070652)
0.3 1.0 GO:0043073 germ cell nucleus(GO:0043073)
0.2 1.5 GO:1990130 Iml1 complex(GO:1990130)
0.2 1.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 1.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 1.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 1.0 GO:0071439 clathrin complex(GO:0071439)
0.2 6.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 0.7 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.2 1.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 0.5 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 1.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 1.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 1.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.6 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 2.2 GO:0036038 MKS complex(GO:0036038)
0.1 0.9 GO:0070847 core mediator complex(GO:0070847)
0.1 1.2 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.2 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 1.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.0 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.2 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 2.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 1.8 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 3.1 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 1.4 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.3 GO:0070461 SAGA-type complex(GO:0070461)
0.1 1.0 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.3 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 1.8 GO:0035861 site of double-strand break(GO:0035861)
0.1 1.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 4.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.0 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 1.2 GO:0043186 P granule(GO:0043186)
0.0 2.7 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 2.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.6 GO:0030286 dynein complex(GO:0030286)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.7 2.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.7 2.9 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.7 3.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.6 1.9 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.6 1.8 GO:0032357 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.5 4.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 1.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.4 2.6 GO:0035173 histone kinase activity(GO:0035173)
0.3 1.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.3 1.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 2.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 2.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.2 1.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 2.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 1.6 GO:0035198 miRNA binding(GO:0035198)
0.2 0.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.2 1.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 2.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 2.9 GO:0002039 p53 binding(GO:0002039)
0.2 2.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.6 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 2.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.7 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 0.4 GO:0031956 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.1 1.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 2.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.9 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 2.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.3 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 2.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 2.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 3.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 3.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 2.0 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 1.2 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 6.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.0 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.6 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.8 GO:0043236 laminin binding(GO:0043236)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.1 GO:0051287 NAD binding(GO:0051287)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 6.1 GO:0003924 GTPase activity(GO:0003924)
0.0 6.1 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 1.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 2.3 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 2.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 4.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0003724 RNA helicase activity(GO:0003724)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 4.8 PID AURORA A PATHWAY Aurora A signaling
0.1 3.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.3 PID MYC PATHWAY C-MYC pathway
0.1 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.8 PID BARD1 PATHWAY BARD1 signaling events
0.1 2.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.1 PID ATM PATHWAY ATM pathway
0.1 0.9 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 2.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 1.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 4.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 3.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.6 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.7 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 4.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.4 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 1.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis