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PRJEB1986: zebrafish developmental stages transcriptome

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Results for myca+mych

Z-value: 0.68

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Transcription factors associated with myca+mych

Gene Symbol Gene ID Gene Info
myca
ENSDARG00000045695 MYC proto-oncogene, bHLH transcription factor a
mych
ENSDARG00000077473 myelocytomatosis oncogene homolog

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycadr11_v1_chr24_+_10414028_104140280.862.8e-06Click!
mychdr11_v1_chr6_+_50451337_50451337-0.038.9e-01Click!

Activity profile of myca+mych motif

Sorted Z-values of myca+mych motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_26531850 2.69 ENSDART00000183317
ENSDART00000131994
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr22_+_5118361 2.01 ENSDART00000168371
ENSDART00000170222
ENSDART00000158846
mibp
muscle-specific beta 1 integrin binding protein
chr20_-_25626198 1.87 ENSDART00000126716
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr13_-_35892051 1.79 ENSDART00000145884
tacc3
transforming, acidic coiled-coil containing protein 3
chr23_+_21459263 1.77 ENSDART00000104209
her4.3
hairy-related 4, tandem duplicate 3
chr5_+_68807170 1.75 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr13_-_25199260 1.54 ENSDART00000057605
adka
adenosine kinase a
chr7_+_49715750 1.52 ENSDART00000019446
ascl1b
achaete-scute family bHLH transcription factor 1b
chr17_-_19534474 1.49 ENSDART00000192469
cyp26c1
cytochrome P450, family 26, subfamily C, polypeptide 1
chr14_-_12822 1.48 ENSDART00000180650
ENSDART00000188819
msx1a
muscle segment homeobox 1a
chr13_+_48359573 1.47 ENSDART00000161959
ENSDART00000165311
msh6
mutS homolog 6 (E. coli)
chr13_-_45022301 1.44 ENSDART00000183589
ENSDART00000125633
ENSDART00000074787
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr20_+_25445826 1.42 ENSDART00000012581
pfas
phosphoribosylformylglycinamidine synthase
chr20_-_25626428 1.37 ENSDART00000136475
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr12_+_27117609 1.32 ENSDART00000076154
hoxb8b
homeobox B8b
chr1_-_19648227 1.29 ENSDART00000054574
polr1e
polymerase (RNA) I polypeptide E
chr9_-_11587070 1.28 ENSDART00000030995
umps
uridine monophosphate synthetase
chr7_-_23745984 1.24 ENSDART00000048050
ITGB1BP2
zgc:92429
chr8_+_26059677 1.22 ENSDART00000009178
impdh2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr1_-_35916247 1.22 ENSDART00000181541
smad1
SMAD family member 1
chr3_+_24595922 1.20 ENSDART00000169405
si:dkey-68o6.5
si:dkey-68o6.5
chr9_+_38158570 1.20 ENSDART00000059549
ENSDART00000133060
nifk
nucleolar protein interacting with the FHA domain of MKI67
chr20_-_53996193 1.18 ENSDART00000004756
hsp90aa1.1
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr20_+_25625872 1.18 ENSDART00000078385
ppat
phosphoribosyl pyrophosphate amidotransferase
chr18_-_127873 1.18 ENSDART00000148490
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr5_-_8765428 1.16 ENSDART00000167793
mybbp1a
MYB binding protein (P160) 1a
chr13_-_12021566 1.13 ENSDART00000125430
pprc1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr10_+_35002786 1.13 ENSDART00000099552
exosc8
exosome component 8
chr22_+_5120033 1.12 ENSDART00000169200
mibp
muscle-specific beta 1 integrin binding protein
chr9_-_11676491 1.11 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr13_+_30912117 1.11 ENSDART00000133138
drgx
dorsal root ganglia homeobox
chr20_-_25626693 1.10 ENSDART00000132247
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr10_+_22034477 1.09 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
npm1a
nucleophosmin 1a
chr14_+_16287968 1.08 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr19_-_24555623 1.08 ENSDART00000176022
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr13_+_30912385 1.08 ENSDART00000182642
drgx
dorsal root ganglia homeobox
chr9_-_31278048 1.06 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr16_-_42186093 1.05 ENSDART00000076030
fbl
fibrillarin
chr20_-_25631256 1.05 ENSDART00000048164
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr3_-_25377163 1.04 ENSDART00000055490
kpna2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr24_+_41690545 1.04 ENSDART00000160069
lama1
laminin, alpha 1
chr19_+_20793388 1.04 ENSDART00000142463
txnl4a
thioredoxin-like 4A
chr6_+_3717613 1.03 ENSDART00000184330
ssb
Sjogren syndrome antigen B (autoantigen La)
chr14_+_22076596 1.02 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
slc43a1a
solute carrier family 43 (amino acid system L transporter), member 1a
chr23_-_21535040 1.02 ENSDART00000010647
rcc2
regulator of chromosome condensation 2
chr14_-_41369629 1.01 ENSDART00000173040
cstf2
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr4_-_2945306 0.99 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr12_+_33975065 0.99 ENSDART00000036649
sfxn2
sideroflexin 2
chr18_-_5850683 0.99 ENSDART00000082087
nip7
NIP7, nucleolar pre-rRNA processing protein
chr20_-_22484621 0.99 ENSDART00000063601
gsx2
GS homeobox 2
chr8_+_23355484 0.98 ENSDART00000085361
ENSDART00000125729
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr1_-_30762264 0.97 ENSDART00000085454
dis3
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
chr21_-_30408775 0.96 ENSDART00000101037
nhp2
NHP2 ribonucleoprotein homolog (yeast)
chr1_+_5485799 0.96 ENSDART00000022307
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr23_-_38160024 0.96 ENSDART00000087112
pfdn4
prefoldin subunit 4
chr19_-_18136410 0.96 ENSDART00000012352
cbx3a
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr23_+_35714574 0.96 ENSDART00000164616
tuba1c
tubulin, alpha 1c
chr7_+_54605640 0.95 ENSDART00000168474
fgf3
fibroblast growth factor 3
chr17_-_42213285 0.95 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr4_+_18963822 0.95 ENSDART00000066975
ENSDART00000066973
impdh1b
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr5_-_55914268 0.93 ENSDART00000014049
wdr36
WD repeat domain 36
chr25_+_19095231 0.93 ENSDART00000154066
isg20
interferon stimulated exonuclease gene
chr9_+_27720428 0.92 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr3_-_12930217 0.91 ENSDART00000166322
pdgfab
platelet-derived growth factor alpha polypeptide b
chr1_-_156375 0.91 ENSDART00000160221
pcid2
PCI domain containing 2
chr10_+_39283985 0.91 ENSDART00000016464
dcps
decapping enzyme, scavenger
chr23_-_21534455 0.91 ENSDART00000139092
rcc2
regulator of chromosome condensation 2
chr12_+_18445604 0.90 ENSDART00000078860
noxo1b
NADPH oxidase organizer 1b
chr14_-_25935167 0.90 ENSDART00000139855
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr16_+_23961276 0.90 ENSDART00000192754
apoeb
apolipoprotein Eb
chr14_+_16151636 0.89 ENSDART00000159352
polr1a
polymerase (RNA) I polypeptide A
chr3_-_37148594 0.88 ENSDART00000140855
mlx
MLX, MAX dimerization protein
chr23_+_36122058 0.88 ENSDART00000184448
hoxc3a
homeobox C3a
chr8_+_26432677 0.88 ENSDART00000078369
ENSDART00000131925
zgc:136971
zgc:136971
chr8_+_15277874 0.87 ENSDART00000146965
dnttip2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr9_+_36967294 0.86 ENSDART00000059753
inhbb
inhibin, beta B
chr6_-_27108844 0.86 ENSDART00000073883
dtymk
deoxythymidylate kinase (thymidylate kinase)
chr19_-_24555935 0.86 ENSDART00000132660
ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr16_-_10223741 0.86 ENSDART00000188099
si:rp71-15i12.1
si:rp71-15i12.1
chr13_+_25200105 0.86 ENSDART00000039640
ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr5_+_3927989 0.86 ENSDART00000030125
znhit3
zinc finger, HIT-type containing 3
chr24_+_36317544 0.85 ENSDART00000048640
ENSDART00000156096
pus3
pseudouridylate synthase 3
chr20_+_25626479 0.83 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr25_+_3231812 0.82 ENSDART00000163647
metap2b
methionyl aminopeptidase 2b
chr23_+_30730121 0.82 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr21_-_26495700 0.82 ENSDART00000109379
cd248b
CD248 molecule, endosialin b
chr17_+_23968214 0.81 ENSDART00000183053
xpo1b
exportin 1 (CRM1 homolog, yeast) b
chr7_+_22801465 0.81 ENSDART00000052862
ENSDART00000173633
rbm4.1
RNA binding motif protein 4.1
chr1_+_26110985 0.81 ENSDART00000054208
mtap
methylthioadenosine phosphorylase
chr5_-_10082244 0.81 ENSDART00000036421
chek2
checkpoint kinase 2
chr22_+_15343953 0.81 ENSDART00000045682
rrp36
ribosomal RNA processing 36
chr9_-_12652984 0.80 ENSDART00000052256
sumo3b
small ubiquitin-like modifier 3b
chr13_-_35907768 0.80 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr4_+_61171310 0.80 ENSDART00000141738
si:dkey-9p20.18
si:dkey-9p20.18
chr14_+_5385855 0.79 ENSDART00000031508
lbx2
ladybird homeobox 2
chr13_-_31370184 0.79 ENSDART00000034829
rrp12
ribosomal RNA processing 12 homolog
chr20_+_1349043 0.79 ENSDART00000186375
tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr17_-_49407091 0.77 ENSDART00000021950
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr9_-_30259295 0.77 ENSDART00000139106
si:dkey-100n23.5
si:dkey-100n23.5
chr12_-_9700605 0.76 ENSDART00000161063
heatr1
HEAT repeat containing 1
chr21_+_6114709 0.75 ENSDART00000065858
fpgs
folylpolyglutamate synthase
chr9_-_27396404 0.75 ENSDART00000136412
ENSDART00000101401
tex30
testis expressed 30
chr25_-_8513255 0.75 ENSDART00000150129
polg
polymerase (DNA directed), gamma
chr25_+_21098990 0.75 ENSDART00000017488
rad52
RAD52 homolog, DNA repair protein
chr15_-_44052927 0.73 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr9_-_27719998 0.73 ENSDART00000161068
ENSDART00000148195
ENSDART00000138386
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr4_-_26032741 0.72 ENSDART00000188058
usp44
ubiquitin specific peptidase 44
chr24_-_16905018 0.72 ENSDART00000066759
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr8_-_39977026 0.71 ENSDART00000141707
asphd2
aspartate beta-hydroxylase domain containing 2
chr21_-_22122312 0.71 ENSDART00000101726
slc35f2
solute carrier family 35, member F2
chr16_-_8520474 0.71 ENSDART00000137365
grb10b
growth factor receptor-bound protein 10b
chr11_+_6009984 0.70 ENSDART00000185680
gtpbp3
GTP binding protein 3, mitochondrial
chr14_+_94603 0.70 ENSDART00000162480
mcm7
minichromosome maintenance complex component 7
chr17_-_42213822 0.69 ENSDART00000187904
ENSDART00000180029
nkx2.2a
NK2 homeobox 2a
chr25_+_21098675 0.66 ENSDART00000079012
rad52
RAD52 homolog, DNA repair protein
chr4_-_64709908 0.66 ENSDART00000161032
si:dkey-9i5.2
si:dkey-9i5.2
chr4_-_38033800 0.66 ENSDART00000159662
si:dkeyp-82b4.4
si:dkeyp-82b4.4
chr11_+_3959495 0.65 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr3_+_18807524 0.65 ENSDART00000055757
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr6_-_8264751 0.64 ENSDART00000091628
ccdc151
coiled-coil domain containing 151
chr14_+_34514336 0.64 ENSDART00000024440
foxi3b
forkhead box I3b
chr11_+_6010177 0.63 ENSDART00000170047
ENSDART00000022526
ENSDART00000161001
ENSDART00000188999
gtpbp3
GTP binding protein 3, mitochondrial
chr19_-_46957968 0.63 ENSDART00000043713
angpt1
angiopoietin 1
chr24_+_16905188 0.63 ENSDART00000066760
cct5
chaperonin containing TCP1, subunit 5 (epsilon)
chr25_+_245438 0.63 ENSDART00000004689
zgc:92481
zgc:92481
chr18_-_11184584 0.62 ENSDART00000040500
tspan9a
tetraspanin 9a
chr21_-_30082414 0.62 ENSDART00000157307
ENSDART00000155188
ccnjl
cyclin J-like
chr16_-_31790285 0.62 ENSDART00000184655
chd4b
chromodomain helicase DNA binding protein 4b
chr11_+_25485774 0.61 ENSDART00000026249
gnl3l
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr16_+_16968682 0.61 ENSDART00000111074
si:ch211-120k19.1
si:ch211-120k19.1
chr2_+_25839193 0.61 ENSDART00000078634
eif5a2
eukaryotic translation initiation factor 5A2
chr1_-_54972170 0.60 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr23_+_38159715 0.60 ENSDART00000137969
zgc:112994
zgc:112994
chr16_+_25761101 0.60 ENSDART00000110619
cblc
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr8_-_30979494 0.60 ENSDART00000138959
si:ch211-251j10.3
si:ch211-251j10.3
chr9_-_27720612 0.60 ENSDART00000000566
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr16_-_38629208 0.59 ENSDART00000126705
eif3ea
eukaryotic translation initiation factor 3, subunit E, a
chr23_+_32499916 0.59 ENSDART00000134811
si:dkey-261h17.1
si:dkey-261h17.1
chr13_-_25408387 0.58 ENSDART00000002741
itprip
inositol 1,4,5-trisphosphate receptor interacting protein
chr24_+_24014880 0.58 ENSDART00000041335
chodl
chondrolectin
chr9_+_41821613 0.57 ENSDART00000097295
col18a1a
collagen type XVIII alpha 1 chain a
chr13_-_4992395 0.57 ENSDART00000102651
nolc1
nucleolar and coiled-body phosphoprotein 1
chr21_+_25068215 0.56 ENSDART00000167523
ENSDART00000189259
dixdc1b
DIX domain containing 1b
chr2_-_11027258 0.56 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
ssbp3a
single stranded DNA binding protein 3a
chr19_-_34117056 0.56 ENSDART00000158677
si:dkey-184p18.2
si:dkey-184p18.2
chr19_+_20201254 0.56 ENSDART00000010140
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr1_-_25438934 0.55 ENSDART00000111686
fhdc1
FH2 domain containing 1
chr14_-_25985698 0.55 ENSDART00000172909
ENSDART00000123053
atox1
antioxidant 1 copper chaperone
chr3_+_28939759 0.54 ENSDART00000141904
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr4_-_25271455 0.54 ENSDART00000066936
tmem110l
transmembrane protein 110, like
chr16_+_16969060 0.54 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
rpl18
si:ch211-120k19.1
ribosomal protein L18
chr6_-_32726848 0.53 ENSDART00000155294
zc3h3
zinc finger CCCH-type containing 3
chr7_-_30779575 0.53 ENSDART00000004782
mphosph10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr20_-_48470599 0.53 ENSDART00000166857
CABZ01059120.1

chr13_-_9295890 0.53 ENSDART00000110680
HTRA2 (1 of many)
si:dkey-33c12.12
chr6_-_18531349 0.52 ENSDART00000160693
ENSDART00000169780
utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr25_-_14424406 0.52 ENSDART00000073609
prmt7
protein arginine methyltransferase 7
chr16_+_33593116 0.51 ENSDART00000013148
pou3f1
POU class 3 homeobox 1
chr18_+_14645568 0.51 ENSDART00000138995
ENSDART00000147351
vps9d1
VPS9 domain containing 1
chr14_+_28432737 0.50 ENSDART00000026846
pin4
protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
chr19_+_20201593 0.50 ENSDART00000163026
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr17_+_24843401 0.50 ENSDART00000110179
cx34.4
connexin 34.4
chr19_-_15855427 0.50 ENSDART00000133059
cited4a
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr21_-_41147818 0.50 ENSDART00000167339
ENSDART00000192730
msx2b
muscle segment homeobox 2b
chr5_-_3927692 0.49 ENSDART00000146840
ENSDART00000058346
c1qbp
complement component 1, q subcomponent binding protein
chr1_-_55750208 0.47 ENSDART00000142244
dnajb1b
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr23_-_21534738 0.46 ENSDART00000134587
rcc2
regulator of chromosome condensation 2
chr15_-_1484795 0.46 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr7_-_55539738 0.46 ENSDART00000168721
ENSDART00000013796
ENSDART00000148514
aprt
adenine phosphoribosyltransferase
chr4_+_53976731 0.45 ENSDART00000165813
si:ch211-249c2.1
si:ch211-249c2.1
chr6_+_54078703 0.45 ENSDART00000110845
fhit
fragile histidine triad gene
chr7_+_30779761 0.44 ENSDART00000066806
ENSDART00000173671
mcee
methylmalonyl CoA epimerase
chr17_-_7028418 0.44 ENSDART00000188305
ENSDART00000187895
sash1b
SAM and SH3 domain containing 1b
chr6_-_58975010 0.44 ENSDART00000144911
ENSDART00000144514
mars
methionyl-tRNA synthetase
chr2_-_59285085 0.44 ENSDART00000131880
ftr34
finTRIM family, member 34
chr9_-_21460164 0.43 ENSDART00000133469
zmym2
zinc finger, MYM-type 2
chr8_+_25295160 0.43 ENSDART00000049793
gstm.1
glutathione S-transferase mu, tandem duplicate 1
chr13_+_39277178 0.43 ENSDART00000113259
si:dkey-85a20.4
si:dkey-85a20.4
chr13_+_25199849 0.42 ENSDART00000139209
ENSDART00000130876
ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr1_-_54971968 0.42 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr18_-_20608025 0.42 ENSDART00000090156
ENSDART00000151980
bcl2l13
BCL2 like 13
chr21_-_11199366 0.42 ENSDART00000167666
dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr17_+_51682429 0.42 ENSDART00000004379
nol10
nucleolar protein 10
chr21_-_28920245 0.41 ENSDART00000132884
cxxc5a
CXXC finger protein 5a
chr8_-_52143109 0.41 ENSDART00000142969
tcf7l1b
transcription factor 7 like 1b
chr3_+_54887782 0.40 ENSDART00000018205
aanat2
arylalkylamine N-acetyltransferase 2
chr22_-_26834043 0.40 ENSDART00000087202
si:dkey-44g23.5
si:dkey-44g23.5
chr18_+_6638726 0.40 ENSDART00000142755
ENSDART00000167781
c2cd5
C2 calcium-dependent domain containing 5
chr14_+_14836468 0.40 ENSDART00000166728
si:dkey-102m7.3
si:dkey-102m7.3
chr24_+_23791758 0.40 ENSDART00000066655
ENSDART00000146580
mybl1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr6_-_21189295 0.39 ENSDART00000137136
obsl1a
obscurin-like 1a
chr7_-_58843193 0.39 ENSDART00000167231
mrpl15
mitochondrial ribosomal protein L15
chr6_-_39080630 0.39 ENSDART00000021520
ENSDART00000128308
eif4bb
eukaryotic translation initiation factor 4Bb
chr24_+_32668675 0.38 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
si:ch211-282b22.1
chr6_-_52348562 0.38 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eif6
eukaryotic translation initiation factor 6
chr3_-_58165254 0.38 ENSDART00000093031
snu13a
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr16_+_32136550 0.38 ENSDART00000147526
sphk2
sphingosine kinase 2
chr9_-_785444 0.37 ENSDART00000012506
en1a
engrailed homeobox 1a
chr14_+_94946 0.36 ENSDART00000165766
ENSDART00000163778
mcm7
minichromosome maintenance complex component 7
chr7_+_52887701 0.36 ENSDART00000109973
tp53bp1
tumor protein p53 binding protein, 1

Network of associatons between targets according to the STRING database.

First level regulatory network of myca+mych

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 9.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.8 0.8 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.5 1.6 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.5 1.5 GO:0006290 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.5 1.4 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.4 1.3 GO:0001113 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.4 1.2 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.4 1.1 GO:0071042 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.3 2.0 GO:0044209 AMP salvage(GO:0044209)
0.3 1.0 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.3 1.0 GO:0021985 neurohypophysis development(GO:0021985)
0.3 0.9 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.3 0.9 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 0.9 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.3 1.2 GO:1904407 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.3 0.9 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.3 1.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.3 1.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.3 1.3 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 1.5 GO:0055014 outflow tract morphogenesis(GO:0003151) atrial cardiac muscle cell development(GO:0055014)
0.2 3.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 2.2 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.2 0.9 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 1.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.8 GO:0070084 protein initiator methionine removal(GO:0070084)
0.2 0.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.7 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 0.5 GO:0071514 genetic imprinting(GO:0071514)
0.2 1.3 GO:0009303 rRNA transcription(GO:0009303)
0.2 0.7 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.2 0.6 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 0.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.8 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 1.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.2 0.8 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.2 1.1 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.1 1.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 1.0 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 0.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.4 GO:1902626 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.8 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.5 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 0.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.7 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.1 1.0 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 2.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.4 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.8 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.1 1.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.6 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.8 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 0.4 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.1 0.2 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 1.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.4 GO:0015961 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.1 1.8 GO:0001757 somite specification(GO:0001757)
0.1 0.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.9 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 2.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.8 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.1 0.6 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.1 1.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.2 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.2 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.4 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 1.5 GO:0043049 otic placode formation(GO:0043049)
0.0 0.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 4.0 GO:0016072 rRNA processing(GO:0006364) rRNA metabolic process(GO:0016072)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 1.5 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.9 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 1.0 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.4 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.2 GO:0003352 regulation of cilium movement(GO:0003352)
0.0 0.8 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 1.7 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 1.8 GO:0051028 mRNA transport(GO:0051028)
0.0 1.8 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.4 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.6 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 1.1 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.1 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 3.0 GO:0001755 neural crest cell migration(GO:0001755)
0.0 1.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.6 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.8 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.4 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.3 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0032301 MutSalpha complex(GO:0032301)
0.3 1.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.2 1.0 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 1.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 1.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 0.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 2.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 2.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 0.9 GO:0070390 transcription export complex 2(GO:0070390)
0.2 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.1 2.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.6 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.1 0.8 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.0 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.6 GO:0030686 90S preribosome(GO:0030686)
0.1 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.2 GO:0043209 myelin sheath(GO:0043209)
0.1 0.5 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.0 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 1.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.4 GO:0030496 midbody(GO:0030496)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0035101 FACT complex(GO:0035101)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 7.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0070938 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.5 3.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.5 1.5 GO:0032143 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.5 3.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.4 2.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 1.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 1.5 GO:0004001 adenosine kinase activity(GO:0004001)
0.3 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 0.9 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.9 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.2 1.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.2 0.6 GO:0047690 aspartyltransferase activity(GO:0047690)
0.2 1.0 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 0.5 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 1.0 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.2 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.5 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.1 0.4 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 0.9 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.5 GO:0016531 copper chaperone activity(GO:0016531)
0.1 1.0 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 2.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.7 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049) nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.7 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 1.3 GO:0030515 snoRNA binding(GO:0030515)
0.1 1.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.4 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 2.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.4 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.5 GO:0008494 translation activator activity(GO:0008494)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 3.3 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.3 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 3.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 1.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.6 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.9 PID AURORA A PATHWAY Aurora A signaling
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.6 PID SHP2 PATHWAY SHP2 signaling
0.0 0.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 3.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 0.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.0 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis