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PRJEB1986: zebrafish developmental stages transcriptome

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Results for myog

Z-value: 0.86

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Transcription factors associated with myog

Gene Symbol Gene ID Gene Info
myog
ENSDARG00000009438 myogenin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
myogdr11_v1_chr11_-_22599584_225995840.716.5e-04Click!

Activity profile of myog motif

Sorted Z-values of myog motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_46201008 5.11 ENSDART00000160110
tgm1l4
transglutaminase 1 like 4
chr21_-_217589 2.31 ENSDART00000185017
CZQB01146713.1

chr17_-_14815557 2.13 ENSDART00000154473
nid2a
nidogen 2a (osteonidogen)
chr7_+_2455344 1.86 ENSDART00000172942
si:dkey-125e8.4
si:dkey-125e8.4
chr20_+_43691208 1.78 ENSDART00000152976
ENSDART00000045185
lin9
lin-9 DREAM MuvB core complex component
chr19_-_47571456 1.73 ENSDART00000158071
ENSDART00000165841
rrm2
ribonucleotide reductase M2 polypeptide
chr20_-_29498178 1.66 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
rrm2
ribonucleotide reductase M2 polypeptide
chr7_+_44715224 1.65 ENSDART00000184630
si:dkey-56m19.5
si:dkey-56m19.5
chr7_+_49715750 1.61 ENSDART00000019446
ascl1b
achaete-scute family bHLH transcription factor 1b
chr21_-_19919020 1.60 ENSDART00000147396
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr19_+_15440841 1.57 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr5_+_32835219 1.56 ENSDART00000140832
ENSDART00000186055
si:ch211-208h16.4
si:ch211-208h16.4
chr17_+_132555 1.56 ENSDART00000158159
zgc:77287
zgc:77287
chr19_+_15441022 1.53 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr5_-_63515210 1.40 ENSDART00000022348
prdm12b
PR domain containing 12b
chr17_-_28097760 1.40 ENSDART00000149861
kdm1a
lysine (K)-specific demethylase 1a
chr11_-_18015534 1.39 ENSDART00000181953
qrich1
glutamine-rich 1
chr14_-_25928899 1.37 ENSDART00000143518
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr25_+_3294150 1.33 ENSDART00000030683
tmpob
thymopoietin b
chr23_+_44461493 1.32 ENSDART00000149854
si:ch1073-228j22.1
si:ch1073-228j22.1
chr2_-_11027258 1.30 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
ssbp3a
single stranded DNA binding protein 3a
chr8_-_18613948 1.28 ENSDART00000089172
cpox
coproporphyrinogen oxidase
chr13_+_30903816 1.26 ENSDART00000191727
ercc6
excision repair cross-complementation group 6
chr24_+_20575259 1.25 ENSDART00000010488
klhl40b
kelch-like family member 40b
chr17_-_14836320 1.22 ENSDART00000157051
nid2a
nidogen 2a (osteonidogen)
chr16_+_19537073 1.21 ENSDART00000190590
sp8b
sp8 transcription factor b
chr19_-_30810328 1.20 ENSDART00000184875
myclb
MYCL proto-oncogene, bHLH transcription factor b
chr11_-_41966854 1.20 ENSDART00000055709
her2
hairy-related 2
chr6_+_40629066 1.19 ENSDART00000103757
slc6a11a
solute carrier family 6 (neurotransmitter transporter), member 11a
chr16_+_19536614 1.18 ENSDART00000112894
ENSDART00000079201
ENSDART00000139357
sp8b
sp8 transcription factor b
chr9_+_21306902 1.17 ENSDART00000138554
ENSDART00000004108
xpo4
exportin 4
chr2_-_17114852 1.17 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr6_-_39313027 1.15 ENSDART00000012644
krt4
keratin 4
chr13_+_11439486 1.14 ENSDART00000138312
zbtb18
zinc finger and BTB domain containing 18
chr14_-_26482096 1.14 ENSDART00000187280
smad5
SMAD family member 5
chr4_-_52165969 1.13 ENSDART00000171130
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr15_-_39969988 1.13 ENSDART00000146054
rps5
ribosomal protein S5
chr3_-_29962345 1.12 ENSDART00000136819
bcat2
branched chain amino-acid transaminase 2, mitochondrial
chr1_+_23563691 1.12 ENSDART00000142879
ncapg
non-SMC condensin I complex, subunit G
chr3_-_19368435 1.11 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr5_-_14509137 1.11 ENSDART00000180742
si:ch211-244o22.2
si:ch211-244o22.2
chr5_-_8164439 1.11 ENSDART00000189912
slc1a3a
solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr16_-_42894628 1.09 ENSDART00000045600
hfe2
hemochromatosis type 2
chr3_+_59935606 1.08 ENSDART00000154157
arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr20_+_34502606 1.05 ENSDART00000139739
gorab
golgin, rab6-interacting
chr17_+_1360192 1.04 ENSDART00000184561
siva1
SIVA1, apoptosis-inducing factor
chr24_+_25210015 1.03 ENSDART00000081043
cip2a
cell proliferation regulating inhibitor of protein phosphatase 2A
chr6_-_32093830 1.03 ENSDART00000017695
foxd3
forkhead box D3
chr23_-_19831739 1.00 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr10_+_33588715 0.99 ENSDART00000051198
mis18a
MIS18 kinetochore protein A
chr4_-_76488581 0.98 ENSDART00000174291
ftr51
finTRIM family, member 51
chr22_-_10541372 0.97 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr13_+_24263049 0.97 ENSDART00000135992
ENSDART00000088005
abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr2_-_21335131 0.97 ENSDART00000057022
klhl40a
kelch-like family member 40a
chr9_+_41024973 0.97 ENSDART00000014660
ENSDART00000144467
ormdl1
ORMDL sphingolipid biosynthesis regulator 1
chr19_-_47570672 0.96 ENSDART00000112155
rrm2
ribonucleotide reductase M2 polypeptide
chr13_+_51579851 0.96 ENSDART00000163847
nkx6.2
NK6 homeobox 2
chr1_+_38142354 0.96 ENSDART00000179352
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr2_-_17115256 0.95 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr19_+_18812805 0.95 ENSDART00000187164
ENSDART00000172412
cratb
carnitine O-acetyltransferase b
chr16_+_26706519 0.93 ENSDART00000142706
virma
vir like m6A methyltransferase associated
chr14_-_41388178 0.93 ENSDART00000124532
ENSDART00000125016
ENSDART00000169247
cstf2
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr8_-_11229523 0.93 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr8_-_1051438 0.93 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr25_-_14637660 0.92 ENSDART00000143666
nav2b
neuron navigator 2b
chr5_+_17780475 0.92 ENSDART00000110783
ENSDART00000115227
chfr
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr11_+_36477481 0.92 ENSDART00000128245
ldlrad2
low density lipoprotein receptor class A domain containing 2
chr2_+_16173999 0.91 ENSDART00000177639
ENSDART00000157601
ENSDART00000190186
ENSDART00000045933
sh3glb1b
SH3-domain GRB2-like endophilin B1b
chr8_-_50259448 0.90 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr13_+_2894536 0.89 ENSDART00000183678
CABZ01087629.1

chr18_-_20444296 0.89 ENSDART00000132993
kif23
kinesin family member 23
chr10_-_44560165 0.88 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr9_+_32872690 0.88 ENSDART00000020798
si:dkey-145p14.5
si:dkey-145p14.5
chr8_-_14609284 0.88 ENSDART00000146175
cep350
centrosomal protein 350
chr16_-_6205790 0.87 ENSDART00000038495
ctnnb1
catenin (cadherin-associated protein), beta 1
chr5_+_31779911 0.87 ENSDART00000098163
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr4_+_8638622 0.87 ENSDART00000186829
wnt5b
wingless-type MMTV integration site family, member 5b
chr15_-_2652640 0.86 ENSDART00000146094
cldnf
claudin f
chr8_-_37043900 0.85 ENSDART00000139567
renbp
renin binding protein
chr5_+_250078 0.85 ENSDART00000127504
trabd2a
TraB domain containing 2A
chr12_+_6002715 0.84 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr8_+_39570615 0.84 ENSDART00000142557
lzts1
leucine zipper, putative tumor suppressor 1
chr18_+_30441740 0.83 ENSDART00000189074
gse1
Gse1 coiled-coil protein
chr4_+_10066840 0.83 ENSDART00000026492
flncb
filamin C, gamma b (actin binding protein 280)
chr13_-_13030851 0.82 ENSDART00000009499
nsd2
nuclear receptor binding SET domain protein 2
chr24_-_9300160 0.82 ENSDART00000152378
tgif1
TGFB-induced factor homeobox 1
chr23_-_19977214 0.82 ENSDART00000054659
ccnq
cyclin Q
chr7_+_41265618 0.82 ENSDART00000173688
scrib
scribbled planar cell polarity protein
chr17_-_51818659 0.82 ENSDART00000111389
ENSDART00000157244
exd2
exonuclease 3'-5' domain containing 2
chr2_+_32016516 0.81 ENSDART00000135040
mycb
MYC proto-oncogene, bHLH transcription factor b
chr20_+_1316495 0.81 ENSDART00000064439
nup43
nucleoporin 43
chr9_-_29578037 0.81 ENSDART00000189026
cenpj
centromere protein J
chr11_-_17755444 0.80 ENSDART00000154627
eogt
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr14_-_9281232 0.80 ENSDART00000054693
asb12b
ankyrin repeat and SOCS box-containing 12b
chr16_-_31469065 0.80 ENSDART00000182397
si:ch211-251p5.5
si:ch211-251p5.5
chr17_+_27434626 0.79 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr8_-_43677762 0.79 ENSDART00000167762
ep400
E1A binding protein p400
chr23_+_20931030 0.78 ENSDART00000167014
pax7b
paired box 7b
chr19_+_26072624 0.78 ENSDART00000147627
jarid2b
jumonji, AT rich interactive domain 2b
chr16_+_33953644 0.77 ENSDART00000164447
ENSDART00000159969
arid1aa
AT rich interactive domain 1Aa (SWI-like)
chr14_+_7939398 0.77 ENSDART00000189773
cxxc5b
CXXC finger protein 5b
chr12_+_47663419 0.77 ENSDART00000171932
HHEX
hematopoietically expressed homeobox
chr16_-_54810464 0.77 ENSDART00000030658
zbtb7b
zinc finger and BTB domain containing 7B
chr18_-_19819812 0.76 ENSDART00000060344
aagab
alpha and gamma adaptin binding protein
chr17_-_10073926 0.76 ENSDART00000166081
ENSDART00000161574
zgc:109986
zgc:109986
chr14_+_7939216 0.76 ENSDART00000171657
cxxc5b
CXXC finger protein 5b
chr5_-_19400166 0.76 ENSDART00000008994
foxn4
forkhead box N4
chr4_+_77993977 0.75 ENSDART00000174118
terfa
telomeric repeat binding factor a
chr14_+_28486213 0.75 ENSDART00000161852
stag2b
stromal antigen 2b
chr25_+_28589669 0.75 ENSDART00000193901
tmem17
transmembrane protein 17
chr12_+_48681601 0.74 ENSDART00000187831
uros
uroporphyrinogen III synthase
chr5_-_20135679 0.74 ENSDART00000079402
usp30
ubiquitin specific peptidase 30
chr7_-_41726657 0.73 ENSDART00000099121
arl8
ADP-ribosylation factor-like 8
chr22_+_465269 0.72 ENSDART00000145767
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr19_-_46957968 0.72 ENSDART00000043713
angpt1
angiopoietin 1
chr17_+_24597001 0.72 ENSDART00000191834
rlf
rearranged L-myc fusion
chr19_-_24757231 0.72 ENSDART00000128177
si:dkey-154b15.1
si:dkey-154b15.1
chr22_+_11153590 0.71 ENSDART00000188207
bcor
BCL6 corepressor
chr23_+_553396 0.70 ENSDART00000034707
lsm14b
LSM family member 14B
chr7_-_38570299 0.70 ENSDART00000143815
celf1
cugbp, Elav-like family member 1
chr25_-_25619550 0.70 ENSDART00000150400
tbc1d2b
TBC1 domain family, member 2B
chr11_-_287670 0.69 ENSDART00000035737
slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr3_+_46559639 0.69 ENSDART00000146189
ENSDART00000127832
ENSDART00000151035
raver1
ribonucleoprotein, PTB-binding 1
chr4_-_76488854 0.69 ENSDART00000132323
ftr51
finTRIM family, member 51
chr8_-_4573545 0.69 ENSDART00000127153
dhx37
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr7_+_5911670 0.68 ENSDART00000173025
si:dkey-23a13.9
si:dkey-23a13.9
chr13_+_25286538 0.68 ENSDART00000180282
chuk
conserved helix-loop-helix ubiquitous kinase
chr6_+_59991076 0.68 ENSDART00000163575
CABZ01100888.1

chr25_-_14433503 0.68 ENSDART00000103957
exoc3l1
exocyst complex component 3-like 1
chr14_+_10596628 0.67 ENSDART00000115177
gpr174
G protein-coupled receptor 174
chr11_+_6136220 0.67 ENSDART00000082223
tax1bp3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr21_-_30026359 0.67 ENSDART00000153645
pwwp2a
PWWP domain containing 2A
chr14_+_21755469 0.67 ENSDART00000186326
kdm2ab
lysine (K)-specific demethylase 2Ab
chr14_-_22118055 0.66 ENSDART00000179892
si:dkey-6i22.5
si:dkey-6i22.5
chr4_+_13412030 0.66 ENSDART00000003694
cand1
cullin-associated and neddylation-dissociated 1
chr1_+_41609676 0.66 ENSDART00000183675
mogs
mannosyl-oligosaccharide glucosidase
chr19_-_2317558 0.65 ENSDART00000190300
sp8a
sp8 transcription factor a
chr4_-_59152337 0.65 ENSDART00000156770
znf1149
zinc finger protein 1149
chr9_+_22657221 0.65 ENSDART00000101765
si:dkey-189g17.2
si:dkey-189g17.2
chr12_+_49125510 0.65 ENSDART00000185804
FO704607.1

chr13_-_31622195 0.64 ENSDART00000057432
six1a
SIX homeobox 1a
chr24_+_39108243 0.64 ENSDART00000156353
mss51
MSS51 mitochondrial translational activator
chr1_-_20271138 0.64 ENSDART00000185931
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr14_-_7375049 0.64 ENSDART00000054809
trappc11
trafficking protein particle complex 11
chr23_-_3408777 0.64 ENSDART00000193245
mafba
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr4_-_21466480 0.63 ENSDART00000139962
pawr
PRKC, apoptosis, WT1, regulator
chr2_-_22492289 0.63 ENSDART00000168022
gtf2b
general transcription factor IIB
chr24_-_17389263 0.63 ENSDART00000122757
cul1b
cullin 1b
chr6_-_32703317 0.63 ENSDART00000064833
mafaa
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr3_-_15139293 0.62 ENSDART00000161213
ENSDART00000146053
fam173a
family with sequence similarity 173, member A
chr17_+_53296851 0.62 ENSDART00000158313
ddx24
DEAD (Asp-Glu-Ala-Asp) box helicase 24
chr2_-_24402341 0.61 ENSDART00000155442
ENSDART00000088572
zgc:154006
zgc:154006
chr13_+_43639867 0.61 ENSDART00000042588
ENSDART00000074728
zfyve21
zinc finger, FYVE domain containing 21
chr14_-_30050 0.61 ENSDART00000164411
zbtb49
zinc finger and BTB domain containing 49
chr15_-_4568154 0.61 ENSDART00000155254
rffl
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr12_-_10476448 0.60 ENSDART00000106172
rac1a
Rac family small GTPase 1a
chr15_+_21254800 0.60 ENSDART00000142902
usf1
upstream transcription factor 1
chr17_+_23968214 0.59 ENSDART00000183053
xpo1b
exportin 1 (CRM1 homolog, yeast) b
chr2_+_6253246 0.59 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr7_+_37742299 0.59 ENSDART00000143300
brd7
bromodomain containing 7
chr24_+_26337623 0.58 ENSDART00000145637
mynn
myoneurin
chr4_+_8532580 0.58 ENSDART00000162065
wnt5b
wingless-type MMTV integration site family, member 5b
chr20_-_33497128 0.58 ENSDART00000101974
erh
enhancer of rudimentary homolog (Drosophila)
chr13_-_3155243 0.58 ENSDART00000139183
ENSDART00000050934
pkdcca
protein kinase domain containing, cytoplasmic a
chr9_-_32300783 0.58 ENSDART00000078596
hspd1
heat shock 60 protein 1
chr14_+_21828993 0.58 ENSDART00000144367
ctbp1
C-terminal binding protein 1
chr12_+_15165736 0.57 ENSDART00000180398
adprh
ADP-ribosylarginine hydrolase
chr8_-_1255321 0.57 ENSDART00000149605
cdc14b
cell division cycle 14B
chr2_+_29995590 0.57 ENSDART00000151906
rbm33b
RNA binding motif protein 33b
chr19_-_43657468 0.57 ENSDART00000150940
si:ch211-193k19.2
si:ch211-193k19.2
chr20_+_46268906 0.56 ENSDART00000113372
taar14e
trace amine associated receptor 14e
chr7_-_20582842 0.56 ENSDART00000169750
ENSDART00000111719
si:dkey-19b23.11
si:dkey-19b23.11
chr14_-_5817039 0.55 ENSDART00000131820
kazald2
Kazal-type serine peptidase inhibitor domain 2
chr9_-_105135 0.55 ENSDART00000180126
FQ377903.3

chr3_-_8285123 0.55 ENSDART00000158699
ENSDART00000138588
trim35-9
tripartite motif containing 35-9
chr11_-_10058 0.54 ENSDART00000173070
myg1
melanocyte proliferating gene 1
chr12_-_26415499 0.54 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr9_-_32300611 0.54 ENSDART00000127938
hspd1
heat shock 60 protein 1
chr23_+_27789795 0.54 ENSDART00000141458
kmt2d
lysine (K)-specific methyltransferase 2D
chr21_-_22317920 0.54 ENSDART00000191083
ENSDART00000108701
gdpd4b
glycerophosphodiester phosphodiesterase domain containing 4b
chr23_+_16948049 0.54 ENSDART00000139449
si:dkey-147f3.4
si:dkey-147f3.4
chr10_+_15454745 0.54 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbin
erbb2 interacting protein
chr19_+_6910384 0.54 ENSDART00000151389
si:ch73-367f21.4
si:ch73-367f21.4
chr2_+_36620011 0.53 ENSDART00000177428
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr4_+_18442941 0.53 ENSDART00000190819
ncaph2
non-SMC condensin II complex, subunit H2
chr10_-_25328814 0.53 ENSDART00000123820
tmem135
transmembrane protein 135
chr10_-_22803740 0.53 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr20_+_25904199 0.53 ENSDART00000016864
slc35f6
solute carrier family 35, member F6
chr20_+_23625387 0.53 ENSDART00000147945
ENSDART00000150497
palld
palladin, cytoskeletal associated protein
chr21_+_33249478 0.53 ENSDART00000169972
si:ch211-151g22.1
si:ch211-151g22.1
chr23_+_26079467 0.52 ENSDART00000129617
atp6ap1b
ATPase H+ transporting accessory protein 1b
chr20_+_19066858 0.52 ENSDART00000192086
sox7
SRY (sex determining region Y)-box 7
chr3_-_49163683 0.51 ENSDART00000166146
dnajb1a
DnaJ (Hsp40) homolog, subfamily B, member 1a
chr7_-_41468942 0.51 ENSDART00000174087
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr25_-_16076257 0.51 ENSDART00000140780
ovch2
ovochymase 2
chr10_+_589501 0.51 ENSDART00000188415
LO018557.1

chr9_-_12885201 0.50 ENSDART00000124957
ankzf1
ankyrin repeat and zinc finger domain containing 1
chr19_+_14454306 0.50 ENSDART00000161965
zdhhc18b
zinc finger, DHHC-type containing 18b
chr18_+_6857071 0.50 ENSDART00000018735
ENSDART00000181969
dnaja2l
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr23_-_7594723 0.50 ENSDART00000115298
plagl2
pleiomorphic adenoma gene-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of myog

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.7 2.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.5 1.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.5 2.4 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.4 4.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 0.9 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.3 1.4 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.3 1.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.3 1.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.3 1.1 GO:0021742 abducens nucleus development(GO:0021742)
0.3 0.8 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.2 1.0 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.2 5.1 GO:0018149 peptide cross-linking(GO:0018149)
0.2 0.7 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.2 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.2 1.0 GO:0097066 response to thyroid hormone(GO:0097066)
0.2 1.2 GO:0007405 neuroblast proliferation(GO:0007405)
0.2 1.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 0.8 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.2 0.7 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.2 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 2.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 0.7 GO:0061113 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.2 0.7 GO:0010039 response to iron ion(GO:0010039)
0.2 1.0 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 0.6 GO:0014857 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.2 0.8 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.2 0.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.4 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.8 GO:1902946 protein localization to early endosome(GO:1902946)
0.1 0.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.8 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.9 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 2.0 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.5 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.8 GO:0061511 centriole elongation(GO:0061511)
0.1 0.5 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.2 GO:0021871 forebrain regionalization(GO:0021871)
0.1 1.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.3 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.6 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.4 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.1 1.2 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.5 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.9 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.3 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.1 0.4 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.4 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 1.1 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.4 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.4 GO:0016037 light absorption(GO:0016037)
0.1 3.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.7 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.9 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 1.1 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 0.2 GO:0060306 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.3 GO:0044806 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.1 0.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.3 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.7 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.2 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.6 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.1 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.5 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 0.4 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.7 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 1.2 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 0.6 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 1.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.4 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.4 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.4 GO:0035108 limb morphogenesis(GO:0035108)
0.0 0.5 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:1903573 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.0 0.9 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.6 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.4 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.1 GO:0021695 cerebellar Purkinje cell layer development(GO:0021680) cerebellar cortex development(GO:0021695)
0.0 0.7 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 1.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:1903076 regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.0 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 1.5 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.9 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.2 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 0.2 GO:0021703 locus ceruleus development(GO:0021703)
0.0 1.2 GO:0060840 artery development(GO:0060840)
0.0 0.6 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 1.0 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.8 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.6 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.1 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.0 1.4 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.6 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0009409 response to cold(GO:0009409)
0.0 1.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 1.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.0 GO:1903817 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 1.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.7 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.7 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.1 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.7 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.3 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.5 GO:0006402 mRNA catabolic process(GO:0006402)
0.0 0.6 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035339 SPOTS complex(GO:0035339)
0.2 1.7 GO:0000796 condensin complex(GO:0000796)
0.2 0.7 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.9 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 4.1 GO:0031672 A band(GO:0031672)
0.1 1.3 GO:0045095 keratin filament(GO:0045095)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 0.8 GO:0035060 brahma complex(GO:0035060)
0.1 1.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.0 GO:0071565 nBAF complex(GO:0071565)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.5 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.4 GO:0005657 replication fork(GO:0005657)
0.1 0.8 GO:0070187 telosome(GO:0070187)
0.0 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 3.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0008278 cohesin complex(GO:0008278)
0.0 1.3 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0045495 pole plasm(GO:0045495)
0.0 2.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172) multimeric ribonuclease P complex(GO:0030681)
0.0 2.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.0 GO:0097541 axonemal basal plate(GO:0097541)
0.0 0.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.0 GO:0000775 chromosome, centromeric region(GO:0000775)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.4 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.5 1.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 2.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 1.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 1.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 5.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.7 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.2 0.8 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 1.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.7 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.4 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 1.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.8 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 1.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 0.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.5 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 0.8 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.6 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.6 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.5 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.4 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.6 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 1.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.5 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.6 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 3.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.3 GO:0019843 rRNA binding(GO:0019843)
0.0 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.0 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.8 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.5 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.4 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.1 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.0 PID AURORA B PATHWAY Aurora B signaling
0.1 4.2 PID E2F PATHWAY E2F transcription factor network
0.1 3.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 4.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 2.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 1.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis