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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nfat5a+nfat5b

Z-value: 0.55

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Transcription factors associated with nfat5a+nfat5b

Gene Symbol Gene ID Gene Info
nfat5a
ENSDARG00000020872 nuclear factor of activated T cells 5a
nfat5b
ENSDARG00000102556 nuclear factor of activated T cells 5b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfat5bdr11_v1_chr7_+_67325933_673259330.541.8e-02Click!
nfat5adr11_v1_chr25_-_37121335_371213350.253.0e-01Click!

Activity profile of nfat5a+nfat5b motif

Sorted Z-values of nfat5a+nfat5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_612594 1.11 ENSDART00000150903
kynu
kynureninase
chr23_-_27875140 1.01 ENSDART00000143662
ankrd33aa
ankyrin repeat domain 33Aa
chr21_+_6291027 0.88 ENSDART00000180467
ENSDART00000184952
ENSDART00000184006
fnbp1b
formin binding protein 1b
chr8_+_1843135 0.87 ENSDART00000141452
snap29
synaptosomal-associated protein 29
chr2_-_37960688 0.86 ENSDART00000055565
cbln14
cerebellin 14
chr16_+_45746549 0.85 ENSDART00000190403
paqr6
progestin and adipoQ receptor family member VI
chr20_-_53624645 0.83 ENSDART00000083427
ENSDART00000152920
slc25a29
solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
chr2_-_26499842 0.82 ENSDART00000186929
BX569796.1

chr2_-_5502256 0.82 ENSDART00000193037
saga
S-antigen; retina and pineal gland (arrestin) a
chr10_+_22782522 0.80 ENSDART00000079498
ENSDART00000145558
si:ch211-237l4.6
si:ch211-237l4.6
chr3_-_5067585 0.76 ENSDART00000169609
tefb
thyrotrophic embryonic factor b
chr18_+_45792035 0.75 ENSDART00000135045
abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr25_-_35136267 0.75 ENSDART00000109751
zgc:173585
zgc:173585
chr18_-_898870 0.75 ENSDART00000151777
ENSDART00000062654
parp6a
poly (ADP-ribose) polymerase family, member 6a
chr1_+_41666611 0.75 ENSDART00000145789
fbxo41
F-box protein 41
chr5_+_13521081 0.74 ENSDART00000171975
si:ch211-230g14.6
si:ch211-230g14.6
chr2_-_37888429 0.73 ENSDART00000183277
mbl2
mannose binding lectin 2
chr1_+_54194801 0.67 ENSDART00000186802
CABZ01067150.1

chr7_+_39444843 0.66 ENSDART00000143999
ENSDART00000173554
ENSDART00000173698
ENSDART00000173754
ENSDART00000144075
ENSDART00000138192
ENSDART00000145457
ENSDART00000141750
ENSDART00000103056
ENSDART00000142946
ENSDART00000173748
tnnt3b
troponin T type 3b (skeletal, fast)
chr5_-_38384289 0.66 ENSDART00000135260
mink1
misshapen-like kinase 1
chr13_+_33024547 0.65 ENSDART00000057377
arg2
arginase 2
chr17_-_33414781 0.65 ENSDART00000142203
ENSDART00000034638
ccdc28a
coiled-coil domain containing 28A
chr17_+_36627099 0.64 ENSDART00000154104
impg1b
interphotoreceptor matrix proteoglycan 1b
chr9_+_7909490 0.59 ENSDART00000133063
ENSDART00000109288
myo16
myosin XVI
chr21_+_5494561 0.56 ENSDART00000169728
ly6m3
lymphocyte antigen 6 family member M3
chr9_-_11263228 0.55 ENSDART00000113847
chpfa
chondroitin polymerizing factor a
chr5_-_49012569 0.55 ENSDART00000184690
si:dkey-172m14.2
si:dkey-172m14.2
chr17_-_277046 0.54 ENSDART00000182587
LO018437.1

chr2_+_33541928 0.49 ENSDART00000162852
BX548164.1

chr3_+_22059066 0.48 ENSDART00000155739
kansl1b
KAT8 regulatory NSL complex subunit 1b
chr17_-_43012390 0.46 ENSDART00000155615
atg2b
autophagy related 2B
chr18_+_9641210 0.43 ENSDART00000182024
pclob
piccolo presynaptic cytomatrix protein b
chr5_-_63109232 0.42 ENSDART00000115128
usp2b
ubiquitin specific peptidase 2b
chr17_+_33415319 0.40 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr2_+_55982300 0.39 ENSDART00000183903
nmrk2
nicotinamide riboside kinase 2
chr7_+_39624728 0.39 ENSDART00000173847
ENSDART00000173845
ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr20_-_1174266 0.38 ENSDART00000023304
gabrr2b
gamma-aminobutyric acid (GABA) A receptor, rho 2b
chr5_-_49011912 0.38 ENSDART00000097450
si:dkey-172m14.2
si:dkey-172m14.2
chr8_+_7144066 0.37 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr23_-_26522760 0.37 ENSDART00000142417
ENSDART00000135606
ENSDART00000122668
si:dkey-205h13.1
si:dkey-205h13.1
chr16_+_2469889 0.36 ENSDART00000126759
cnih4
cornichon family AMPA receptor auxiliary protein 4
chr2_-_24369087 0.36 ENSDART00000081237
plvapa
plasmalemma vesicle associated protein a
chr12_-_30549022 0.35 ENSDART00000102474
zgc:158404
zgc:158404
chr24_-_20656773 0.35 ENSDART00000190883
ENSDART00000193896
nktr
natural killer cell triggering receptor
chr3_+_40856095 0.34 ENSDART00000143207
mmd2a
monocyte to macrophage differentiation-associated 2a
chr21_+_22840246 0.34 ENSDART00000151621
birc2
baculoviral IAP repeat containing 2
chr6_+_40992883 0.33 ENSDART00000076061
tgfa
transforming growth factor, alpha
chr10_+_4807913 0.33 ENSDART00000186099
palm2
paralemmin 2
chr24_-_28229618 0.33 ENSDART00000145290
bcl2a
BCL2, apoptosis regulator a
chr11_-_30611814 0.33 ENSDART00000089803
slc8a1a
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr23_+_26102028 0.32 ENSDART00000139488
si:dkey-78k11.4
si:dkey-78k11.4
chr13_-_11667661 0.32 ENSDART00000102411
dctn1b
dynactin 1b
chr1_+_2712956 0.31 ENSDART00000126093
gpc6a
glypican 6a
chr5_-_62940851 0.31 ENSDART00000137052
specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr17_+_33311784 0.30 ENSDART00000156229
si:ch211-132f19.7
si:ch211-132f19.7
chr4_+_57093908 0.30 ENSDART00000170198
si:ch211-238e22.5
si:ch211-238e22.5
chr5_-_13353810 0.30 ENSDART00000146136
ENSDART00000099602
ENSDART00000004539
ube2l3b
ubiquitin-conjugating enzyme E2L 3b
chr3_-_30434016 0.30 ENSDART00000150958
lrrc4ba
leucine rich repeat containing 4Ba
chr12_-_17147473 0.29 ENSDART00000106035
stambpl1
STAM binding protein-like 1
chr2_-_42492201 0.29 ENSDART00000180762
ENSDART00000009093
esyt2a
extended synaptotagmin-like protein 2a
chr21_+_2742823 0.29 ENSDART00000189004
CABZ01073424.2

chr15_-_18209672 0.28 ENSDART00000141508
ENSDART00000136280
btr16
bloodthirsty-related gene family, member 16
chr7_-_2285314 0.28 ENSDART00000153614
si:dkey-187j14.6
si:dkey-187j14.6
chr4_+_35594200 0.25 ENSDART00000193902
si:dkeyp-4c4.2
si:dkeyp-4c4.2
chr19_+_32807236 0.25 ENSDART00000008698
stk3
serine/threonine kinase 3 (STE20 homolog, yeast)
chr19_-_8748571 0.24 ENSDART00000031173
rps27.1
ribosomal protein S27, isoform 1
chr9_+_310331 0.23 ENSDART00000172446
ENSDART00000187731
ENSDART00000193970
stac3
SH3 and cysteine rich domain 3
chr19_-_36234185 0.23 ENSDART00000186003
csmd2
CUB and Sushi multiple domains 2
chr10_+_2981090 0.23 ENSDART00000111830
zfyve16
zinc finger, FYVE domain containing 16
chr7_-_29115772 0.22 ENSDART00000076386
fbxl8
F-box and leucine-rich repeat protein 8
chr4_+_76722754 0.21 ENSDART00000153867
ms4a17a.3
membrane-spanning 4-domains, subfamily A, member 17A.3
chr1_+_19616799 0.21 ENSDART00000143077
fbxo10
F-box protein 10
chr13_+_22104298 0.21 ENSDART00000115393
si:dkey-174i8.1
si:dkey-174i8.1
chr5_-_40040488 0.21 ENSDART00000157755
cds1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr2_-_36925561 0.21 ENSDART00000187690
map1sb
microtubule-associated protein 1Sb
chr7_-_2285499 0.20 ENSDART00000182211
si:dkey-187j14.6
si:dkey-187j14.6
chr2_-_34483597 0.20 ENSDART00000133224
brinp2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr2_-_24348948 0.19 ENSDART00000136559
ano8a
anoctamin 8a
chr9_+_53725128 0.19 ENSDART00000169062
cnmd
chondromodulin
chr20_-_40720458 0.19 ENSDART00000153151
ENSDART00000061261
ENSDART00000138569
cx43
connexin 43
chr9_+_53725294 0.19 ENSDART00000165991
cnmd
chondromodulin
chr10_+_44955106 0.18 ENSDART00000185837
il1b
interleukin 1, beta
chr16_+_33902006 0.18 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr23_-_45897900 0.18 ENSDART00000149263
ftr92
finTRIM family, member 92
chr5_-_42904329 0.17 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr20_-_29787192 0.17 ENSDART00000125348
ENSDART00000048759
id2b
inhibitor of DNA binding 2b
chr10_+_15255012 0.16 ENSDART00000023766
vldlr
very low density lipoprotein receptor
chr1_+_56502706 0.16 ENSDART00000188665
CABZ01059403.1

chr10_+_21722892 0.16 ENSDART00000162855
pcdh1g13
protocadherin 1 gamma 13
chr2_-_24348642 0.15 ENSDART00000181739
ano8a
anoctamin 8a
chr17_+_15559046 0.14 ENSDART00000187126
bach2a
BTB and CNC homology 1, basic leucine zipper transcription factor 2a
chr10_-_40968095 0.14 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr21_+_44557006 0.14 ENSDART00000170159
cmc4
C-x(9)-C motif containing 4 homolog (S. cerevisiae)
chr5_-_9948497 0.14 ENSDART00000183196
tor4ab
torsin family 4, member Ab
chr6_+_6802142 0.14 ENSDART00000065566
dtd1
D-tyrosyl-tRNA deacylase 1
chr6_+_58607488 0.14 ENSDART00000182648
helz2
helicase with zinc finger 2, transcriptional coactivator
chr6_-_19381993 0.13 ENSDART00000164114
grb2a
growth factor receptor-bound protein 2a
chr7_+_29009161 0.13 ENSDART00000166458
CR376738.1

chr24_-_20599781 0.13 ENSDART00000179664
ENSDART00000141823
zbtb47b
zinc finger and BTB domain containing 47b
chr10_-_32465462 0.13 ENSDART00000134056
uvrag
UV radiation resistance associated gene
chr6_+_612330 0.13 ENSDART00000166872
ENSDART00000191758
kynu
kynureninase
chr25_-_13842618 0.12 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr24_-_19719240 0.12 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr5_+_13353866 0.12 ENSDART00000099611
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr23_+_28770225 0.11 ENSDART00000132179
ENSDART00000142273
masp2
mannan-binding lectin serine peptidase 2
chr21_-_14762944 0.11 ENSDART00000114096
arrdc1b
arrestin domain containing 1b
chr12_-_33859950 0.11 ENSDART00000131181
sema4gb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Gb
chr4_-_52504961 0.11 ENSDART00000163123
si:dkey-78o7.3
si:dkey-78o7.3
chr11_-_30612166 0.11 ENSDART00000177984
slc8a1a
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr5_-_37900350 0.11 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
tmprss13b
transmembrane protease, serine 13b
chr10_-_42882215 0.10 ENSDART00000180580
ENSDART00000187374
FP236542.1

chr5_-_19988772 0.10 ENSDART00000086881
slc6a4b
solute carrier family 6 (neurotransmitter transporter), member 4b
chr14_-_25599002 0.10 ENSDART00000040955
slc25a48
solute carrier family 25, member 48
chr20_-_487783 0.09 ENSDART00000162218
col10a1b
collagen, type X, alpha 1b
chr10_-_37072776 0.09 ENSDART00000110835
myo18aa
myosin XVIIIAa
chr14_+_23970818 0.09 ENSDART00000123338
ENSDART00000124944
kif3a
kinesin family member 3A
chr2_-_41518340 0.09 ENSDART00000130830
otomp
otolith matrix protein
chr23_+_36771593 0.08 ENSDART00000078240
march9
membrane-associated ring finger (C3HC4) 9
chr12_+_34891529 0.08 ENSDART00000015643
tbcc
tubulin folding cofactor C
chr1_+_54124209 0.08 ENSDART00000187730
LO017722.1

chr3_-_2033105 0.07 ENSDART00000135249
si:dkey-88j15.3
si:dkey-88j15.3
chr18_+_26895994 0.07 ENSDART00000098347
ch25hl1.2
cholesterol 25-hydroxylase like 1, tandem duplicate 2
chr4_+_47751483 0.07 ENSDART00000160043
si:ch211-196f19.1
si:ch211-196f19.1
chr24_-_21674950 0.07 ENSDART00000123216
ENSDART00000046211
lnx2a
ligand of numb-protein X 2a
chr20_-_23852174 0.06 ENSDART00000122414
si:dkey-15j16.6
si:dkey-15j16.6
chr3_-_29688370 0.06 ENSDART00000151147
ENSDART00000151679
si:ch73-233k15.2
si:ch73-233k15.2
chr4_-_53047883 0.06 ENSDART00000157496
si:dkey-201g16.5
si:dkey-201g16.5
chr15_-_25099679 0.06 ENSDART00000154628
rflnb
refilin B
chr12_-_17024079 0.05 ENSDART00000129027
ifit11
interferon-induced protein with tetratricopeptide repeats 11
chr7_+_48667081 0.05 ENSDART00000083473
trpm5
transient receptor potential cation channel, subfamily M, member 5
chr2_+_3881000 0.05 ENSDART00000081897
mpp7b
membrane protein, palmitoylated 7b (MAGUK p55 subfamily member 7)
chr16_+_43077909 0.05 ENSDART00000014140
rundc3b
RUN domain containing 3b
chr22_-_32360464 0.05 ENSDART00000148886
pcbp4
poly(rC) binding protein 4
chr2_+_55982940 0.05 ENSDART00000097753
ENSDART00000097751
nmrk2
nicotinamide riboside kinase 2
chr9_+_21243985 0.05 ENSDART00000131586
si:rp71-68n21.12
si:rp71-68n21.12
chr13_+_1015749 0.05 ENSDART00000190982
prokr1b
prokineticin receptor 1b
chr13_-_41155472 0.05 ENSDART00000160588
si:dkeyp-86d6.2
si:dkeyp-86d6.2
chr19_-_4785734 0.05 ENSDART00000113088
st3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr3_+_50172452 0.04 ENSDART00000191224
epn3a
epsin 3a
chr20_-_52631998 0.04 ENSDART00000145283
ENSDART00000139072
si:ch211-221n20.1
si:ch211-221n20.1
chr13_+_23623346 0.04 ENSDART00000057619
il22ra2
interleukin 22 receptor, alpha 2
chr9_+_1352603 0.04 ENSDART00000146016
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr21_+_15435946 0.04 ENSDART00000137491
si:dkey-11o15.10
si:dkey-11o15.10
chr16_+_29303971 0.04 ENSDART00000087149
hapln2
hyaluronan and proteoglycan link protein 2
chr3_+_32080403 0.03 ENSDART00000124943
aldh16a1
aldehyde dehydrogenase 16 family, member A1
chr19_-_25149034 0.03 ENSDART00000148432
ENSDART00000175266
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr18_+_41772474 0.03 ENSDART00000097547
trpc6b
transient receptor potential cation channel, subfamily C, member 6b
chr2_-_37862380 0.02 ENSDART00000186005
si:ch211-284o19.8
si:ch211-284o19.8
chr22_+_1680628 0.02 ENSDART00000166672
si:dkey-1b17.6
si:dkey-1b17.6
chr15_+_37950556 0.02 ENSDART00000153947
si:dkey-238d18.12
si:dkey-238d18.12
chr19_+_43885770 0.02 ENSDART00000135599
lypla2
lysophospholipase II
chr1_-_493218 0.02 ENSDART00000031635
ercc5
excision repair cross-complementation group 5
chr4_-_58883559 0.02 ENSDART00000164546
si:dkey-28i19.4
si:dkey-28i19.4
chr1_-_29658721 0.01 ENSDART00000132063
si:dkey-1h24.6
si:dkey-1h24.6
chr7_-_56793739 0.01 ENSDART00000082842
si:ch211-146m13.3
si:ch211-146m13.3
chr10_+_21730585 0.01 ENSDART00000188576
pcdh1g22
protocadherin 1 gamma 22
chr14_-_33218418 0.00 ENSDART00000163046
si:dkey-31j3.11
si:dkey-31j3.11
chr6_+_51932563 0.00 ENSDART00000181778
angpt4
angiopoietin 4

Network of associatons between targets according to the STRING database.

First level regulatory network of nfat5a+nfat5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.2 0.9 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 0.9 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.3 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 0.6 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.8 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.8 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.5 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.0 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.3 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.7 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.1 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.0 0.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.2 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.3 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.8 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.4 GO:0072348 sulfur compound transport(GO:0072348)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.4 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.5 GO:0044545 NSL complex(GO:0044545)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.9 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.7 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0015222 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins