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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nfil3-5

Z-value: 2.16

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Transcription factors associated with nfil3-5

Gene Symbol Gene ID Gene Info
ENSDARG00000094965 nuclear factor, interleukin 3 regulated, member 5
ENSDARG00000113345 nuclear factor, interleukin 3 regulated, member 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfil3-5dr11_v1_chr6_+_8172227_81722270.361.3e-01Click!

Activity profile of nfil3-5 motif

Sorted Z-values of nfil3-5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_44953349 9.29 ENSDART00000135156
villin 1
chr20_-_1151265 9.11 ENSDART00000012376
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr17_+_27456804 9.06 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr25_+_34984333 8.34 ENSDART00000154760
coiled-coil domain containing 136b
chr3_+_16612574 7.45 ENSDART00000104481
solute carrier family 17 (vesicular glutamate transporter), member 7a
chr9_-_48736388 7.19 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr6_-_345503 7.13 ENSDART00000168901
phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a
chr5_+_37837245 7.11 ENSDART00000171617
ependymin
chr25_+_15354095 6.70 ENSDART00000090397
KIAA1549-like a
chr2_+_24177190 6.45 ENSDART00000099546
microtubule associated protein 4 like
chr21_-_22115136 6.36 ENSDART00000134715
ENSDART00000089246
ENSDART00000139789
ELMO/CED-12 domain containing 1
chr20_-_25533739 6.23 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr22_+_20720808 6.21 ENSDART00000171321
si:dkey-211f22.5
chr5_+_51594209 6.20 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
creatine kinase, mitochondrial 2b (sarcomeric)
chr5_-_41494831 6.12 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr21_-_43550120 5.96 ENSDART00000151627
si:ch73-362m14.2
chr3_+_15296824 5.76 ENSDART00000043801
calcium binding protein 5b
chr5_+_51597677 5.70 ENSDART00000048210
ENSDART00000184797
creatine kinase, mitochondrial 2b (sarcomeric)
chr20_+_1121458 5.62 ENSDART00000064472
proline-rich nuclear receptor coactivator 1
chr2_+_10134345 5.60 ENSDART00000100725
alpha-2-HS-glycoprotein 2
chr21_-_22114625 5.57 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr20_-_44576949 5.53 ENSDART00000148639
UBX domain protein 2A
chr7_-_26457208 5.31 ENSDART00000173519
zgc:172079
chr12_+_15002757 5.21 ENSDART00000135036
myosin light chain, phosphorylatable, fast skeletal muscle b
chr9_-_44953664 5.05 ENSDART00000188558
ENSDART00000185210
villin 1
chr10_-_24371312 4.96 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr5_+_4332220 4.90 ENSDART00000051699
spermidine/spermine N1-acetyltransferase 1a, duplicate 1
chr19_-_20093341 4.78 ENSDART00000129917
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr16_-_45069882 4.70 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr20_-_52939501 4.56 ENSDART00000166508
farnesyl-diphosphate farnesyltransferase 1
chr11_-_10770053 4.56 ENSDART00000179213
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr12_-_15205087 4.53 ENSDART00000010068
sulfotransferase family 1, cytosolic sulfotransferase 6
chr8_-_39903803 4.51 ENSDART00000012391
calcium binding protein 1a
chr15_+_37559570 4.48 ENSDART00000085522
heat shock protein, alpha-crystallin-related, b6
chr5_+_1278092 4.48 ENSDART00000147972
ENSDART00000159783
dynamin 1a
chr17_-_20979077 4.45 ENSDART00000006676
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr8_-_32497815 4.33 ENSDART00000122359
si:dkey-164f24.2
chr18_-_898870 4.32 ENSDART00000151777
ENSDART00000062654
poly (ADP-ribose) polymerase family, member 6a
chr1_-_8101495 4.28 ENSDART00000161938
si:dkeyp-9d4.3
chr14_+_4151379 4.22 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr3_+_23092762 4.16 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr1_-_14233815 4.14 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr21_-_42007213 4.14 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr7_+_38717624 4.12 ENSDART00000132522
synaptotagmin XIII
chr7_-_6604623 4.11 ENSDART00000172874
potassium inwardly-rectifying channel, subfamily J, member 10a
chr8_-_37263524 4.04 ENSDART00000061327
Rh50-like protein
chr2_+_38039857 4.04 ENSDART00000159951
calsequestrin 1a
chr17_+_15845765 4.03 ENSDART00000130881
ENSDART00000074936
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr19_-_657439 3.98 ENSDART00000167100
solute carrier family 6 (neutral amino acid transporter), member 18
chr22_-_354592 3.96 ENSDART00000155769
transmembrane protein 240b
chr16_+_46111849 3.92 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr9_-_18742704 3.91 ENSDART00000145401
TSC22 domain family, member 1
chr6_-_37403444 3.87 ENSDART00000136314
cystathionase (cystathionine gamma-lyase), like
chr23_+_19590006 3.81 ENSDART00000021231
sarcolemma associated protein b
chr23_+_37323962 3.78 ENSDART00000102881
family with sequence similarity 43, member B
chr19_+_4990320 3.77 ENSDART00000147056
zgc:91968
chr17_-_23709347 3.74 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr19_+_5674907 3.73 ENSDART00000042189
pyruvate dehydrogenase kinase, isozyme 2b
chr14_-_21219659 3.72 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr19_+_4990496 3.71 ENSDART00000151050
ENSDART00000017535
zgc:91968
chr21_+_43178831 3.65 ENSDART00000151512
AF4/FMR2 family, member 4
chr23_+_45579497 3.64 ENSDART00000110381
early growth response 4
chr5_+_62340799 3.62 ENSDART00000074117
aspartoacylase
chr8_+_8459192 3.60 ENSDART00000140942
ENSDART00000014939
catechol-O-methyltransferase a
chr11_+_714386 3.57 ENSDART00000167824
ENSDART00000187110
TIMP metallopeptidase inhibitor 4, tandem duplicate 3
chr21_-_42202792 3.57 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr1_+_11881559 3.54 ENSDART00000166981
sorting nexin 8b
chr18_-_7539166 3.54 ENSDART00000133541
si:dkey-30c15.2
chr13_+_27314795 3.53 ENSDART00000128726
eukaryotic translation elongation factor 1 alpha 1a
chr17_-_14613711 3.53 ENSDART00000157345
serine dehydratase-like
chr11_+_3585934 3.52 ENSDART00000055694
cytidine deaminase b
chr3_+_7763114 3.50 ENSDART00000057434
hook microtubule-tethering protein 2
chr23_+_33963619 3.48 ENSDART00000140666
ENSDART00000084792
pyridoxal phosphate binding protein
chr24_-_17023392 3.47 ENSDART00000106058
prostaglandin D2 synthase b, tandem duplicate 2
chr6_-_13187168 3.46 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr1_-_14234076 3.41 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr16_+_39146696 3.40 ENSDART00000121756
ENSDART00000084381
syntabulin (syntaxin-interacting)
chr6_-_43449013 3.36 ENSDART00000122423
2-epi-5-epi-valiolone synthase
chr24_-_38079261 3.30 ENSDART00000105662
C-reactive protein 1
chr10_-_17284055 3.30 ENSDART00000167464
G protein subunit alpha z
chr2_+_7192966 3.27 ENSDART00000142735
si:ch211-13f8.1
chr3_+_12732382 3.25 ENSDART00000158403
cytochrome P450, family 2, subfamily k, polypeptide 19
chr11_+_25619892 3.25 ENSDART00000146647
ENSDART00000033702
catechol-O-methyltransferase b
chr11_-_33960318 3.24 ENSDART00000087597
collagen, type VI, alpha 2
chr23_+_19590598 3.24 ENSDART00000170149
sarcolemma associated protein b
chr23_-_30960506 3.22 ENSDART00000142661
oxysterol binding protein-like 2a
chr12_+_46960579 3.17 ENSDART00000149032
ornithine aminotransferase
chr18_+_8346920 3.15 ENSDART00000083421
carnitine palmitoyltransferase 1B (muscle)
chr9_-_16109001 3.12 ENSDART00000053473
uridine phosphorylase 2
chr3_-_61162750 3.10 ENSDART00000055064
parvalbumin 8
chr23_+_4022620 3.08 ENSDART00000055099
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr4_-_14915268 3.08 ENSDART00000067040
si:dkey-180p18.9
chr25_-_9805269 3.05 ENSDART00000192048
leucine rich repeat containing 4C
chr17_-_43466317 3.04 ENSDART00000155313
heat shock protein 4 like
chr4_+_3389866 3.04 ENSDART00000153834
synaptophysin-like 1
chr11_+_30161168 3.03 ENSDART00000157385
cyclin-dependent kinase-like 5
chr1_+_54673846 3.02 ENSDART00000145018
G protein-coupled receptor, class C, group 5, member Bb
chr21_-_43949208 3.02 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr3_-_28665291 3.00 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr3_-_35602233 2.99 ENSDART00000055269
guanine nucleotide binding protein (G protein), gamma 13b
chr6_+_28051978 2.95 ENSDART00000143218
si:ch73-194h10.2
chr4_-_22671469 2.94 ENSDART00000050753
CD36 molecule (thrombospondin receptor)
chr11_+_30161699 2.93 ENSDART00000190504
cyclin-dependent kinase-like 5
chr9_+_46644633 2.91 ENSDART00000160285
solute carrier family 4 (anion exchanger), member 3
chr13_-_27675212 2.89 ENSDART00000141035
regulating synaptic membrane exocytosis 1a
chr11_+_6819050 2.88 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr7_-_32833153 2.86 ENSDART00000099871
ENSDART00000099872
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr19_-_28367413 2.84 ENSDART00000079092
si:dkey-261i16.5
chr5_-_22001003 2.80 ENSDART00000134393
ENSDART00000143878
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr13_+_25396896 2.79 ENSDART00000041257
glutathione S-transferase omega 2
chr5_-_21970881 2.77 ENSDART00000182907
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr12_-_7806007 2.74 ENSDART00000190359
ankyrin 3b
chr1_+_44127292 2.72 ENSDART00000160542
calcium binding protein 2a
chr23_+_18944388 2.71 ENSDART00000104487
cytochrome c oxidase subunit IV isoform 2
chr13_-_37254777 2.65 ENSDART00000139734
spectrin repeat containing, nuclear envelope 2b
chr24_-_39772045 2.65 ENSDART00000087441
si:ch211-276f18.2
chr3_-_33880951 2.64 ENSDART00000013228
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a
chr10_+_24627683 2.64 ENSDART00000112652
solute carrier family 46, member 3
chr4_-_77432218 2.60 ENSDART00000158683
solute carrier organic anion transporter family, member 1D1
chr24_-_10897511 2.57 ENSDART00000145593
ENSDART00000102484
ENSDART00000066784
family with sequence similarity 49, member Bb
chr19_-_5254699 2.54 ENSDART00000081951
syntaxin 1B
chr3_+_37827373 2.52 ENSDART00000039517
acid-sensing (proton-gated) ion channel 2
chr13_+_25397098 2.51 ENSDART00000132953
glutathione S-transferase omega 2
chr12_-_26383242 2.49 ENSDART00000152941
ubiquitin specific peptidase 54b
chr4_+_3482312 2.49 ENSDART00000109044
glutamate receptor, metabotropic 8a
chr25_+_33192796 2.48 ENSDART00000125892
ENSDART00000121680
ENSDART00000014851
zgc:171719
chr9_-_43375205 2.47 ENSDART00000138436
zinc finger protein 385B
chr21_-_7687544 2.46 ENSDART00000134519
phosphodiesterase 8B
chr8_-_32497581 2.44 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
chr9_+_310331 2.44 ENSDART00000172446
ENSDART00000187731
ENSDART00000193970
SH3 and cysteine rich domain 3
chr14_-_18671334 2.41 ENSDART00000182381
SLIT and NTRK-like family, member 4
chr10_+_36650222 2.40 ENSDART00000126963
uncoupling protein 3
chr18_+_924949 2.40 ENSDART00000170888
ENSDART00000193163
pyruvate kinase M1/2a
chr9_+_13682133 2.36 ENSDART00000175639
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr14_+_33458294 2.35 ENSDART00000075278
ATPase Na+/K+ transporting subunit beta 4
chr8_+_1187928 2.27 ENSDART00000127252
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr25_-_17528994 2.27 ENSDART00000061712
si:dkey-44k1.5
chr14_+_21699414 2.24 ENSDART00000169942
syntaxin 3A
chr18_-_1228688 2.22 ENSDART00000064403
neuroplastin b
chr9_+_45227028 2.21 ENSDART00000185579
adenosine deaminase, RNA-specific, B1b
chr21_-_21148623 2.21 ENSDART00000184364
ankyrin 1, erythrocytic b
chr6_-_35472923 2.21 ENSDART00000185907
regulator of G protein signaling 8
chr8_+_23703680 2.20 ENSDART00000141099
ENSDART00000135394
peroxisome proliferator-activated receptor delta b
chr23_-_21763598 2.19 ENSDART00000145408
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr9_-_135774 2.18 ENSDART00000160435

chr7_+_30787903 2.17 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr4_-_5302866 2.13 ENSDART00000138590
si:ch211-214j24.9
chr20_+_38201644 2.12 ENSDART00000022694
EH-domain containing 3
chr15_-_4969525 2.11 ENSDART00000157223
lipoyl(octanoyl) transferase 2
chr5_+_15350954 2.10 ENSDART00000140990
ENSDART00000137287
ENSDART00000061653
phosphatidylethanolamine binding protein 1
chr6_+_41255485 2.09 ENSDART00000042683
ENSDART00000186013
Ca2+-dependent activator protein for secretion b
chr16_-_33104944 2.09 ENSDART00000151943
proline-rich nuclear receptor coactivator 2
chr7_+_34297271 2.09 ENSDART00000180342
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr14_-_30587814 2.08 ENSDART00000144912
ENSDART00000149714
transmembrane protein 265
chr18_+_1703984 2.07 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr16_+_34493987 2.04 ENSDART00000138374
si:ch211-255i3.4
chr3_-_40945710 2.02 ENSDART00000138719
ENSDART00000102416
cytochrome P450, family 3, subfamily C, polypeptide 4
chr20_-_44496245 2.02 ENSDART00000012229
FK506 binding protein 1b
chr8_+_22478090 2.00 ENSDART00000170263
si:ch211-261n11.7
chr4_+_12013043 1.99 ENSDART00000130692
cryptochrome circadian clock 1aa
chr14_-_9199968 1.97 ENSDART00000146113
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr7_+_17716601 1.96 ENSDART00000173792
ENSDART00000080825
reticulon 3
chr4_-_5291256 1.94 ENSDART00000150864
si:ch211-214j24.9
chr13_-_22766445 1.91 ENSDART00000140151
si:ch211-150i13.1
chr7_+_48761875 1.90 ENSDART00000003690
aggrecan a
chr25_-_10564721 1.90 ENSDART00000154776
galanin/GMAP prepropeptide
chr2_+_8261109 1.89 ENSDART00000024677
deleted in autism 1a
chr25_+_33192404 1.87 ENSDART00000193592
zgc:171719
chr16_+_16826504 1.86 ENSDART00000108691
potassium inwardly-rectifying channel, subfamily J, member 14
chr25_-_17552299 1.84 ENSDART00000154327
si:dkey-44k1.5
chr14_+_45645024 1.80 ENSDART00000168278
si:ch211-276i12.4
chr5_-_55848358 1.80 ENSDART00000130891
calcium/calmodulin-dependent protein kinase IV
chr6_-_1553314 1.80 ENSDART00000077209
transmembrane protein, adipocyte asscociated 1
chr11_-_7078392 1.79 ENSDART00000112156
ENSDART00000188556
si:ch211-253b8.5
chr19_+_23982466 1.79 ENSDART00000080673
synaptotagmin XIa
chr1_+_51721851 1.79 ENSDART00000040397
peroxiredoxin 2
chr13_+_10945337 1.76 ENSDART00000091845
ATP-binding cassette, sub-family G (WHITE), member 5
chr11_+_25278772 1.75 ENSDART00000188630
cylindromatosis (turban tumor syndrome), b
chr11_+_6295370 1.73 ENSDART00000139882
RAN binding protein 3a
chr15_+_7992906 1.73 ENSDART00000090790
cell adhesion molecule 2b
chr7_-_66877058 1.72 ENSDART00000155954
adrenomedullin a
chr6_+_8315050 1.71 ENSDART00000189987
glutaryl-CoA dehydrogenase a
chr23_-_42093537 1.70 ENSDART00000122074
solute carrier family 1 (glutamate transporter), member 7b
chr4_+_12013642 1.68 ENSDART00000067281
cryptochrome circadian clock 1aa
chr5_-_55848511 1.67 ENSDART00000183503
calcium/calmodulin-dependent protein kinase IV
chr15_+_28096152 1.67 ENSDART00000100293
ENSDART00000140092
crystallin, beta B1, like 3
chr23_-_5032587 1.64 ENSDART00000163903
potassium voltage-gated channel, shaker-related subfamily, member 2b
chr17_-_5610514 1.64 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr7_-_38792543 1.63 ENSDART00000157416
si:dkey-23n7.10
chr7_+_18176162 1.63 ENSDART00000109171
Ras converting CAAX endopeptidase 1a
chr25_+_34581494 1.63 ENSDART00000167690
transient receptor potential cation channel, subfamily M, member 1b
chr4_-_5302162 1.62 ENSDART00000177099
si:ch211-214j24.9
chr22_-_37686966 1.61 ENSDART00000192217
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr13_+_1182257 1.60 ENSDART00000033528
ENSDART00000183702
ENSDART00000147959
tumor necrosis factor, alpha-induced protein 3
chr21_-_22827548 1.60 ENSDART00000079161
angiopoietin-like 5
chr6_-_50404732 1.60 ENSDART00000055510
reactive oxygen species modulator 1
chr7_-_69429561 1.60 ENSDART00000127351
ataxin 1-like
chr22_+_5682635 1.59 ENSDART00000140680
ENSDART00000131308
deoxyribonuclease 1 like 4, tandem duplicate 2
chr5_+_69808763 1.59 ENSDART00000143482
fibronectin type III and SPRY domain containing 1-like
chr9_-_30432778 1.59 ENSDART00000138364
gap junction protein alpha 8 paralog a

Network of associatons between targets according to the STRING database.

First level regulatory network of nfil3-5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.3 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
2.3 9.1 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
1.3 4.0 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.3 10.3 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
1.2 3.7 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.2 4.9 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
1.2 7.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
1.2 3.5 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.0 6.9 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
1.0 2.9 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.9 11.9 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.9 4.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.9 3.5 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.9 3.4 GO:0060074 synapse maturation(GO:0060074)
0.8 3.3 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.8 4.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.8 2.4 GO:0014808 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.7 2.1 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.7 13.0 GO:0042574 retinal metabolic process(GO:0042574)
0.6 8.3 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.6 3.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.6 4.1 GO:0036268 swimming(GO:0036268)
0.6 4.6 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.6 3.9 GO:0019346 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.6 2.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.5 3.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 1.6 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.5 4.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.5 7.5 GO:0090382 phagosome maturation(GO:0090382)
0.4 4.2 GO:0044206 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.4 3.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.4 4.1 GO:0034694 response to prostaglandin(GO:0034694)
0.4 3.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 2.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 1.0 GO:0042730 fibrinolysis(GO:0042730)
0.3 5.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.3 7.5 GO:0015701 bicarbonate transport(GO:0015701)
0.3 1.6 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.3 1.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039) positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.3 0.9 GO:0036076 ligamentous ossification(GO:0036076)
0.3 2.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.3 2.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.3 1.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 3.2 GO:0009437 carnitine metabolic process(GO:0009437)
0.3 6.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 1.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 3.4 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.2 3.0 GO:0050909 sensory perception of taste(GO:0050909)
0.2 1.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 3.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 1.6 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 0.6 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.2 2.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 3.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 2.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 2.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.2 3.6 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.2 1.3 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.2 9.5 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.2 0.9 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.2 1.8 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 7.9 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.2 1.8 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.2 1.5 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.2 1.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.2 1.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.2 4.5 GO:0051923 sulfation(GO:0051923)
0.2 2.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 1.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 1.4 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 9.7 GO:0006414 translational elongation(GO:0006414)
0.1 1.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 1.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 1.3 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.8 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 1.4 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.1 2.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 3.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 4.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.6 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 1.8 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 2.6 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 1.0 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 1.6 GO:0042493 response to drug(GO:0042493)
0.1 3.0 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 5.7 GO:0006096 glycolytic process(GO:0006096)
0.1 0.7 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 3.7 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.1 1.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 2.2 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.8 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 7.7 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 2.1 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.3 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 3.8 GO:0015914 phospholipid transport(GO:0015914)
0.1 2.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 3.1 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 3.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 3.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 2.0 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.6 GO:0060402 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.1 13.4 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 1.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.9 GO:1990573 potassium ion import(GO:0010107) potassium ion import across plasma membrane(GO:1990573)
0.1 6.5 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 1.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 2.3 GO:0006814 sodium ion transport(GO:0006814)
0.0 1.1 GO:0007631 feeding behavior(GO:0007631)
0.0 3.0 GO:0003146 heart jogging(GO:0003146)
0.0 1.0 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 3.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 2.6 GO:0070509 calcium ion import(GO:0070509)
0.0 0.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 7.0 GO:0006936 muscle contraction(GO:0006936)
0.0 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 1.3 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 5.0 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 5.3 GO:0021782 glial cell development(GO:0021782)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 2.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 1.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 1.3 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 1.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.9 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 3.0 GO:0051260 protein homooligomerization(GO:0051260)
0.0 3.0 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 2.7 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.1 GO:1902369 mitochondrion morphogenesis(GO:0070584) negative regulation of RNA catabolic process(GO:1902369)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.9 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.4 GO:0015671 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.0 1.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.8 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0032482 Rab protein signal transduction(GO:0032482)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 14.3 GO:0032433 filopodium tip(GO:0032433)
2.0 6.0 GO:0032839 dendrite cytoplasm(GO:0032839)
1.0 7.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.7 10.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.6 7.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.6 20.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.6 4.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.5 3.0 GO:0070062 extracellular exosome(GO:0070062)
0.5 3.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 4.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 5.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 2.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 3.9 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 2.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 1.4 GO:0033270 paranode region of axon(GO:0033270)
0.2 9.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 2.4 GO:0030315 T-tubule(GO:0030315)
0.1 1.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 2.1 GO:0060170 ciliary membrane(GO:0060170)
0.1 1.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.6 GO:0005922 connexon complex(GO:0005922)
0.1 3.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 2.9 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.1 0.5 GO:0005883 neurofilament(GO:0005883)
0.1 1.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.1 4.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.6 GO:0001650 fibrillar center(GO:0001650)
0.1 10.4 GO:0070382 exocytic vesicle(GO:0070382)
0.1 2.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.3 GO:0097224 sperm connecting piece(GO:0097224)
0.1 7.8 GO:0014069 postsynaptic density(GO:0014069)
0.1 3.1 GO:0005902 microvillus(GO:0005902)
0.1 0.5 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 16.1 GO:0005764 lysosome(GO:0005764)
0.1 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 3.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.4 GO:0016586 RSC complex(GO:0016586)
0.0 4.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.0 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.8 GO:0008278 cohesin complex(GO:0008278)
0.0 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.2 GO:0030175 filopodium(GO:0030175)
0.0 1.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 12.8 GO:0043005 neuron projection(GO:0043005)
0.0 22.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.7 GO:0045202 synapse(GO:0045202)
0.0 5.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 17.1 GO:0005576 extracellular region(GO:0005576)
0.0 2.2 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
1.7 6.9 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
1.5 4.6 GO:0004311 farnesyltranstransferase activity(GO:0004311)
1.2 3.7 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.2 4.7 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
1.0 3.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.9 11.9 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.9 7.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.8 10.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.8 2.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 2.9 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.7 5.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.7 3.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.7 2.1 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.7 4.9 GO:0019809 spermidine binding(GO:0019809)
0.7 2.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.6 2.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 20.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.6 2.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.6 3.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.6 1.8 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.6 2.3 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.6 3.9 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.5 7.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.5 4.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.5 3.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 3.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 1.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.4 1.7 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.4 4.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 2.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 3.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.4 1.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.4 1.5 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.3 2.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.3 7.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 7.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.3 1.0 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.3 1.0 GO:0003913 DNA photolyase activity(GO:0003913)
0.3 4.1 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.3 0.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 14.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.3 1.5 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.3 3.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 13.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3 1.3 GO:0050699 WW domain binding(GO:0050699)
0.3 1.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 2.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.0 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.2 4.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 4.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 9.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 2.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 2.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 1.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.6 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 3.3 GO:0005080 protein kinase C binding(GO:0005080)
0.2 0.7 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 2.2 GO:0030507 spectrin binding(GO:0030507)
0.2 1.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 6.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 6.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 6.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 9.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.4 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.6 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 3.2 GO:0008483 transaminase activity(GO:0008483)
0.1 1.0 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0004061 arylformamidase activity(GO:0004061)
0.1 1.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.6 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.3 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.5 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 2.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 2.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.1 5.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 2.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 2.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 7.4 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 2.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.0 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 2.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 2.9 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 3.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.7 GO:0044325 ion channel binding(GO:0044325)
0.1 3.0 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 10.0 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 1.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.8 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 8.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 16.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 3.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 3.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 5.5 GO:0015293 symporter activity(GO:0015293)
0.0 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 1.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 7.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 24.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 3.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.0 0.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 6.5 GO:0008017 microtubule binding(GO:0008017)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0005158 insulin receptor binding(GO:0005158)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 3.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 4.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 3.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 2.1 PID AURORA B PATHWAY Aurora B signaling
0.1 2.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.5 13.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.4 1.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.4 3.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 3.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 1.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.3 3.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 4.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 3.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 6.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 3.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 3.5 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.2 4.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 2.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 4.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 4.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 4.6 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 4.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 2.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation