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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nkx2.4a+nkx2.4b

Z-value: 0.40

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Transcription factors associated with nkx2.4a+nkx2.4b

Gene Symbol Gene ID Gene Info
nkx2.4a
ENSDARG00000075107 NK2 homeobox 4a
nkx2.4b
ENSDARG00000104107 NK2 homeobox 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.4adr11_v1_chr17_-_42097267_420972670.652.5e-03Click!
nkx2.4bdr11_v1_chr20_+_48803248_488032480.436.6e-02Click!

Activity profile of nkx2.4a+nkx2.4b motif

Sorted Z-values of nkx2.4a+nkx2.4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_16898140 1.15 ENSDART00000152656
MGC174155
Cathepsin L1-like
chr1_+_25696798 0.96 ENSDART00000054228
lrata
lecithin retinol acyltransferase a
chr12_-_16720432 0.83 ENSDART00000152261
ENSDART00000152154
si:dkey-26g8.4
si:dkey-26g8.4
chr17_-_42213285 0.51 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr20_+_48782068 0.49 ENSDART00000159275
nkx2.2b
NK2 homeobox 2b
chr7_-_35708450 0.44 ENSDART00000193886
irx5a
iroquois homeobox 5a
chr8_-_23776399 0.44 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr24_-_13272842 0.44 ENSDART00000146790
ENSDART00000066703
rdh10a
retinol dehydrogenase 10a
chr15_+_9072821 0.42 ENSDART00000154463
si:dkey-202g17.3
si:dkey-202g17.3
chr7_+_25323742 0.41 ENSDART00000110347
cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr6_-_13114821 0.41 ENSDART00000164579
ENSDART00000165375
zgc:194469
zgc:194469
chr12_-_28848015 0.41 ENSDART00000153200
si:ch211-194k22.8
si:ch211-194k22.8
chr25_-_27842654 0.39 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr17_+_27434626 0.39 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr1_-_38171648 0.39 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr19_+_10847118 0.38 ENSDART00000189784
apoa4a
apolipoprotein A-IV a
chr12_+_5977777 0.37 ENSDART00000152302
si:ch211-131k2.2
si:ch211-131k2.2
chr17_-_106291 0.37 ENSDART00000160738
arhgap11a
Rho GTPase activating protein 11A
chr1_+_15062 0.37 ENSDART00000169005
cep97
centrosomal protein 97
chr10_-_10863936 0.37 ENSDART00000180568
nrarpa
NOTCH regulated ankyrin repeat protein a
chr10_+_31244619 0.37 ENSDART00000145562
ENSDART00000184412
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr5_+_34981584 0.36 ENSDART00000134795
ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr10_-_17179415 0.36 ENSDART00000131751
depdc5
DEP domain containing 5
chr8_+_39607466 0.35 ENSDART00000097427
msi1
musashi RNA-binding protein 1
chr12_-_1361517 0.34 ENSDART00000188297
LO018020.2

chr10_+_21807497 0.34 ENSDART00000164634
pcdh1g32
protocadherin 1 gamma 32
chr1_+_31658011 0.34 ENSDART00000192203
poll
polymerase (DNA directed), lambda
chr17_-_28097760 0.33 ENSDART00000149861
kdm1a
lysine (K)-specific demethylase 1a
chr10_-_10864331 0.33 ENSDART00000122657
nrarpa
NOTCH regulated ankyrin repeat protein a
chr9_-_23033818 0.32 ENSDART00000022392
rnd3b
Rho family GTPase 3b
chr15_-_23485752 0.32 ENSDART00000152706
nlrx1
NLR family member X1
chr5_-_39171302 0.32 ENSDART00000020808
paqr3a
progestin and adipoQ receptor family member IIIa
chr1_-_59232267 0.31 ENSDART00000169658
ENSDART00000163257
akap8l
A kinase (PRKA) anchor protein 8-like
chr1_-_31657854 0.30 ENSDART00000085309
dpcd
deleted in primary ciliary dyskinesia homolog (mouse)
chr1_+_31657842 0.30 ENSDART00000057880
poll
polymerase (DNA directed), lambda
chr6_+_58832155 0.29 ENSDART00000144842
dctn2
dynactin 2 (p50)
chr8_-_22558773 0.29 ENSDART00000074309
porcnl
porcupine O-acyltransferase like
chr5_+_56119975 0.29 ENSDART00000083137
mrm1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr19_-_25113660 0.28 ENSDART00000035538
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr7_+_26049818 0.28 ENSDART00000173611
si:dkey-6n21.12
si:dkey-6n21.12
chr22_-_28373698 0.27 ENSDART00000157592
si:ch211-213c4.5
si:ch211-213c4.5
chr5_+_36896933 0.27 ENSDART00000151984
srsf7a
serine/arginine-rich splicing factor 7a
chr15_-_12011390 0.26 ENSDART00000187403
si:dkey-202l22.6
si:dkey-202l22.6
chr11_-_438294 0.26 ENSDART00000040812
nuf2
NUF2, NDC80 kinetochore complex component, homolog
chr7_-_18601206 0.26 ENSDART00000111636
DTX4
si:ch211-119e14.2
chr7_+_39664055 0.25 ENSDART00000146171
zgc:158564
zgc:158564
chr12_+_27243059 0.25 ENSDART00000066269
arl4d
ADP-ribosylation factor-like 4D
chr4_+_15942075 0.25 ENSDART00000147964
si:dkey-117n7.2
si:dkey-117n7.2
chr5_-_54554583 0.25 ENSDART00000158865
ENSDART00000158069
ssna1
Sjogren syndrome nuclear autoantigen 1
chr2_-_32668668 0.24 ENSDART00000190450
puf60a
poly-U binding splicing factor a
chr19_-_17303500 0.24 ENSDART00000162355
sf3a3
splicing factor 3a, subunit 3
chr9_+_22634073 0.24 ENSDART00000181822
etv5a
ets variant 5a
chr17_-_42213822 0.24 ENSDART00000187904
ENSDART00000180029
nkx2.2a
NK2 homeobox 2a
chr3_-_26805455 0.24 ENSDART00000180648
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr6_-_13114406 0.23 ENSDART00000188015
zgc:194469
zgc:194469
chr4_-_965267 0.23 ENSDART00000093289
atp23
ATP23 metallopeptidase and ATP synthase assembly factor homolog
chr22_-_18241390 0.22 ENSDART00000083879
tmem161a
transmembrane protein 161A
chr2_-_38284648 0.22 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
si:ch211-14a17.7
chr20_+_23742574 0.22 ENSDART00000050559
sh3rf1
SH3 domain containing ring finger 1
chr3_+_32571929 0.21 ENSDART00000151025
si:ch73-248e21.1
si:ch73-248e21.1
chr9_+_31222026 0.21 ENSDART00000145573
clybl
citrate lyase beta like
chr21_-_41147818 0.21 ENSDART00000167339
ENSDART00000192730
msx2b
muscle segment homeobox 2b
chr14_-_26536504 0.21 ENSDART00000105933
tgfbi
transforming growth factor, beta-induced
chr13_-_48388726 0.21 ENSDART00000169473
fbxo11a
F-box protein 11a
chr18_+_23397010 0.21 ENSDART00000193765
mctp2a
multiple C2 domains, transmembrane 2a
chr4_+_23126558 0.20 ENSDART00000162859
mdm2
MDM2 oncogene, E3 ubiquitin protein ligase
chr3_+_13600714 0.19 ENSDART00000162124
hspbp1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr16_+_23924040 0.18 ENSDART00000161124
si:dkey-7f3.14
si:dkey-7f3.14
chr22_-_18240968 0.18 ENSDART00000027605
tmem161a
transmembrane protein 161A
chr25_-_14424406 0.18 ENSDART00000073609
prmt7
protein arginine methyltransferase 7
chr6_-_42073367 0.18 ENSDART00000154304
grm2a
glutamate receptor, metabotropic 2a
chr1_-_21599219 0.18 ENSDART00000148327
adamtsl7
ADAMTS-like 7
chr10_+_5268054 0.18 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr15_-_8517555 0.18 ENSDART00000140213
npas1
neuronal PAS domain protein 1
chr9_+_25832329 0.18 ENSDART00000130059
zeb2a
zinc finger E-box binding homeobox 2a
chr7_-_26049282 0.18 ENSDART00000136389
ENSDART00000101124
rnaseka
ribonuclease, RNase K a
chr1_+_22654875 0.17 ENSDART00000019698
ENSDART00000161874
anxa5b
annexin A5b
chr17_+_43659940 0.17 ENSDART00000145738
ENSDART00000075619
adob
2-aminoethanethiol (cysteamine) dioxygenase b
chr3_+_58354852 0.17 ENSDART00000155715
vwa3a
von Willebrand factor A domain containing 3A
chr1_+_29862074 0.17 ENSDART00000133905
ENSDART00000136786
ENSDART00000135252
pcca
propionyl CoA carboxylase, alpha polypeptide
chr3_-_11008532 0.17 ENSDART00000165086
CR382337.3

chr9_-_24970018 0.17 ENSDART00000026924
dnah7
dynein, axonemal, heavy chain 7
chr8_-_30316436 0.16 ENSDART00000111358
ENSDART00000167065
zgc:162939
zgc:162939
chr10_-_9346360 0.16 ENSDART00000039536
mrrf
mitochondrial ribosome recycling factor
chr17_-_31044803 0.16 ENSDART00000185941
ENSDART00000152016
eml1
echinoderm microtubule associated protein like 1
chr6_+_49028874 0.16 ENSDART00000175254
slc16a1a
solute carrier family 16 (monocarboxylate transporter), member 1a
chr22_+_19111444 0.15 ENSDART00000109655
fgf22
fibroblast growth factor 22
chr4_+_77038392 0.15 ENSDART00000186818
si:dkey-172k15.6
si:dkey-172k15.6
chr2_+_36608387 0.15 ENSDART00000159541
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr5_+_53824959 0.15 ENSDART00000169565
sat2b
spermidine/spermine N1-acetyltransferase family member 2b
chr10_+_9346383 0.15 ENSDART00000064975
ENSDART00000141869
rbm18
RNA binding motif protein 18
chr11_+_39120306 0.15 ENSDART00000155746
ENSDART00000154158
cdc42
cell division cycle 42
chr15_-_28569786 0.15 ENSDART00000127845
ssh2a
slingshot protein phosphatase 2a
chr4_-_17838179 0.14 ENSDART00000146931
avpr2l
arginine vasopressin receptor 2, like
chr15_-_14193926 0.14 ENSDART00000162707
pnkp
polynucleotide kinase 3'-phosphatase
chr7_+_29163762 0.14 ENSDART00000173762
slc38a8b
solute carrier family 38, member 8b
chr3_+_33340939 0.14 ENSDART00000128786
pyya
peptide YYa
chr2_+_17540720 0.14 ENSDART00000114638
pimr198
Pim proto-oncogene, serine/threonine kinase, related 198
chr4_+_44454270 0.13 ENSDART00000150482
si:dkeyp-100h4.4
si:dkeyp-100h4.4
chr4_+_23127104 0.13 ENSDART00000139543
mdm2
MDM2 oncogene, E3 ubiquitin protein ligase
chr13_-_42530656 0.13 ENSDART00000084327
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr11_+_24046179 0.13 ENSDART00000006703
maf1
MAF1 homolog, negative regulator of RNA polymerase III
chr11_-_438492 0.13 ENSDART00000137121
ENSDART00000133784
nuf2
NUF2, NDC80 kinetochore complex component, homolog
chr8_-_39859688 0.12 ENSDART00000019907
unc119.1
unc-119 homolog 1
chr15_+_850829 0.12 ENSDART00000157374
si:dkey-77f5.11
si:dkey-77f5.11
chr19_+_31044487 0.12 ENSDART00000143494
ankmy2b
ankyrin repeat and MYND domain containing 2b
chr15_-_28904371 0.12 ENSDART00000155154
eml2
echinoderm microtubule associated protein like 2
chr19_+_40250682 0.12 ENSDART00000102888
cdk6
cyclin-dependent kinase 6
chr14_+_23158021 0.12 ENSDART00000084664
enox2
ecto-NOX disulfide-thiol exchanger 2
chr14_-_30876708 0.12 ENSDART00000147597
ubl3b
ubiquitin-like 3b
chr8_-_17516448 0.12 ENSDART00000100667
skia
v-ski avian sarcoma viral oncogene homolog a
chr15_-_26552393 0.12 ENSDART00000150152
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr8_-_47152001 0.11 ENSDART00000163922
ENSDART00000110512
ENSDART00000024320
ybx1
Y box binding protein 1
chr4_+_50410452 0.11 ENSDART00000146006
si:dkey-156k2.8
si:dkey-156k2.8
chr15_-_14194208 0.11 ENSDART00000188237
ENSDART00000183155
ENSDART00000165520
pnkp
polynucleotide kinase 3'-phosphatase
chr1_+_58242498 0.11 ENSDART00000149091
ggt1l2.2
gamma-glutamyltransferase 1 like 2.2
chr15_+_1137337 0.11 ENSDART00000191508
p2ry13
purinergic receptor P2Y13
chr4_+_17245217 0.11 ENSDART00000184215
ENSDART00000110908
casc1
cancer susceptibility candidate 1
chr23_+_6795709 0.11 ENSDART00000149136
si:ch211-117c9.5
si:ch211-117c9.5
chr22_+_39096911 0.10 ENSDART00000157127
ENSDART00000153841
lmcd1
LIM and cysteine-rich domains 1
chr2_+_17524278 0.10 ENSDART00000165633
pimr196
Pim proto-oncogene, serine/threonine kinase, related 196
chr2_+_47754419 0.10 ENSDART00000188221
mbnl1
muscleblind-like splicing regulator 1
chr22_-_7457247 0.10 ENSDART00000106081
BX511034.2

chr14_-_8816933 0.10 ENSDART00000163383
si:dkeyp-115e12.7
si:dkeyp-115e12.7
chr20_+_27464721 0.10 ENSDART00000189552
kif26aa
kinesin family member 26Aa
chr23_+_4348479 0.09 ENSDART00000182425
mybl2a
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr18_+_33340868 0.09 ENSDART00000099139
v2rh14
vomeronasal 2 receptor, h14
chr4_-_11098539 0.09 ENSDART00000135511
si:dkey-21h14.12
si:dkey-21h14.12
chr11_+_12879635 0.09 ENSDART00000182515
ENSDART00000081296
si:dkey-11m19.5
si:dkey-11m19.5
chr13_+_25761279 0.09 ENSDART00000177818
ENSDART00000002863
neurog3
neurogenin 3
chr22_-_18387059 0.09 ENSDART00000007769
tssk6
testis-specific serine kinase 6
chr4_+_17843717 0.09 ENSDART00000113507
apaf1
apoptotic peptidase activating factor 1
chr15_-_1590858 0.09 ENSDART00000081875
nnr
nanor
chr16_-_27543024 0.09 ENSDART00000147737
ENSDART00000078283
tex10
testis expressed 10
chr8_+_53120278 0.09 ENSDART00000125232
nr2c2
nuclear receptor subfamily 2, group C, member 2
chr18_-_7481036 0.08 ENSDART00000101292
si:dkey-238c7.16
si:dkey-238c7.16
chr22_+_12770877 0.08 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr7_-_35126374 0.08 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr7_+_39416336 0.08 ENSDART00000171783
CT030188.1

chr20_-_43079478 0.08 ENSDART00000060982
snx9b
sorting nexin 9b
chr12_-_19279103 0.08 ENSDART00000186669
si:ch211-141o9.10
si:ch211-141o9.10
chr14_+_23709543 0.08 ENSDART00000136909
gnpda1
glucosamine-6-phosphate deaminase 1
chr10_+_2742499 0.07 ENSDART00000122847
grk5
G protein-coupled receptor kinase 5
chr13_-_13294847 0.07 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr24_+_33392698 0.07 ENSDART00000122579
si:ch73-173p19.1
si:ch73-173p19.1
chr17_-_8673278 0.07 ENSDART00000171850
ENSDART00000017337
ENSDART00000148504
ENSDART00000148808
ctbp2a
C-terminal binding protein 2a
chr4_-_60312069 0.07 ENSDART00000167207
si:dkey-248e17.4
si:dkey-248e17.4
chr21_+_15865523 0.07 ENSDART00000155098
gcnt4b
glucosaminyl (N-acetyl) transferase 4, core 2, b
chr6_+_374875 0.07 ENSDART00000171698
si:zfos-169g10.3
si:zfos-169g10.3
chr5_+_32882688 0.07 ENSDART00000008807
ENSDART00000185317
rpl12
ribosomal protein L12
chr25_+_19485198 0.07 ENSDART00000156730
glsl
glutaminase like
chr10_-_15048781 0.07 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
si:ch211-95j8.2
chr5_-_34964830 0.07 ENSDART00000133170
arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr20_+_263056 0.06 ENSDART00000132669
tube1
tubulin, epsilon 1
chr23_+_4348265 0.06 ENSDART00000136287
mybl2a
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr19_-_23594914 0.06 ENSDART00000132145
pimr85
Pim proto-oncogene, serine/threonine kinase, related 85
chr19_-_3261019 0.06 ENSDART00000134407
si:ch211-133n4.12
si:ch211-133n4.12
chr16_+_24971717 0.06 ENSDART00000156958
fpr1
formyl peptide receptor 1
chr12_+_10599604 0.06 ENSDART00000152538
lrrc3ca
leucine rich repeat containing 3Ca
chr1_-_7603734 0.06 ENSDART00000009315
mxb
myxovirus (influenza) resistance B
chr5_+_36870737 0.06 ENSDART00000145182
slc8a2a
solute carrier family 8 (sodium/calcium exchanger), member 2a
chr17_+_43032529 0.06 ENSDART00000055611
ENSDART00000154863
isca2
iron-sulfur cluster assembly 2
chr8_-_29658171 0.06 ENSDART00000147755
mpeg1.3
macrophage expressed 1, tandem duplicate 3
chr2_-_11648731 0.06 ENSDART00000080925
impad1
inositol monophosphatase domain containing 1
chr17_-_8673567 0.06 ENSDART00000192714
ENSDART00000012546
ctbp2a
C-terminal binding protein 2a
chr6_-_46782176 0.06 ENSDART00000185559
igfn1.4
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 4
chr21_+_19062124 0.05 ENSDART00000134746
rpl17
ribosomal protein L17
chr21_-_18991165 0.05 ENSDART00000012574
si:ch211-222n4.6
si:ch211-222n4.6
chr19_-_23452345 0.05 ENSDART00000136875
pimr82
Pim proto-oncogene, serine/threonine kinase, related 82
chr1_-_14234076 0.05 ENSDART00000040049
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr1_-_23294753 0.04 ENSDART00000013263
ugdh
UDP-glucose 6-dehydrogenase
chr14_+_21106444 0.04 ENSDART00000075744
ENSDART00000132363
aldob
aldolase b, fructose-bisphosphate
chr21_-_14310159 0.04 ENSDART00000155097
si:ch211-196i2.1
si:ch211-196i2.1
chr12_+_19208338 0.04 ENSDART00000110415
sh3bp1
SH3-domain binding protein 1
chr1_-_28950366 0.03 ENSDART00000110270
pwp2h
PWP2 periodic tryptophan protein homolog (yeast)
chr2_-_6292510 0.03 ENSDART00000092182
ppm1la
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr7_-_5039562 0.03 ENSDART00000154438
ltb4r
leukotriene B4 receptor
chr2_+_16652238 0.02 ENSDART00000091351
gk5
glycerol kinase 5 (putative)
chr15_+_34963316 0.02 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr17_-_10122204 0.02 ENSDART00000160751
BX088587.1

chr9_+_159720 0.02 ENSDART00000166215
cldn10l2
claudin 10-like 2
chr14_-_30876299 0.02 ENSDART00000180305
ubl3b
ubiquitin-like 3b
chr23_-_18982499 0.02 ENSDART00000012507
bcl2l1
bcl2-like 1
chr10_+_8481660 0.02 ENSDART00000109559
BX682234.1

chr2_-_51507540 0.02 ENSDART00000166605
ENSDART00000161093
pigrl2.3
polymeric immunoglobulin receptor-like 2.3
chr1_-_38816685 0.01 ENSDART00000075230
asb5b
ankyrin repeat and SOCS box containing 5b
chr4_-_65747476 0.01 ENSDART00000142421
si:dkey-28k24.2
si:dkey-28k24.2
chr8_+_48480529 0.01 ENSDART00000186631
PRDM16
si:ch211-263k4.2
chr10_-_9086716 0.01 ENSDART00000140095
arl15b
ADP-ribosylation factor-like 15b
chr4_-_43731342 0.01 ENSDART00000146627
si:ch211-226o13.3
si:ch211-226o13.3
chr1_-_14233815 0.01 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr5_+_63767376 0.01 ENSDART00000138898
rgs3b
regulator of G protein signaling 3b
chr15_+_22722684 0.00 ENSDART00000156760
grik4
glutamate receptor, ionotropic, kainate 4
chr3_+_24134418 0.00 ENSDART00000156204
si:ch211-246i5.5
si:ch211-246i5.5
chr21_+_30084823 0.00 ENSDART00000154573
prob1
proline-rich basic protein 1
chr19_+_23982466 0.00 ENSDART00000080673
syt11a
synaptotagmin XIa

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.4a+nkx2.4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.4 GO:0035992 tendon formation(GO:0035992)
0.1 0.4 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 1.4 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.3 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.4 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 0.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.2 GO:0071514 genetic imprinting(GO:0071514)
0.0 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.4 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.2 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.0 0.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.5 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 0.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0034650 cortisol metabolic process(GO:0034650)
0.0 0.0 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.0 0.1 GO:0002283 neutrophil activation involved in immune response(GO:0002283)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.1 0.2 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0019809 spermidine binding(GO:0019809)
0.0 0.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0016841 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.0 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.4 GO:0071855 neuropeptide receptor binding(GO:0071855)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus