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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nkx3-1

Z-value: 0.55

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Transcription factors associated with nkx3-1

Gene Symbol Gene ID Gene Info
nkx3-1
ENSDARG00000078280 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx3-1dr11_v1_chr8_-_50259448_50259448-0.427.1e-02Click!

Activity profile of nkx3-1 motif

Sorted Z-values of nkx3-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_22680560 0.99 ENSDART00000133761
ponzr4
plac8 onzin related protein 4
chr9_-_22158325 0.97 ENSDART00000114568
crygm2d16
crystallin, gamma M2d16
chr9_-_22158784 0.95 ENSDART00000167850
crygm2d14
crystallin, gamma M2d14
chr14_-_33894915 0.92 ENSDART00000143290
urp1
urotensin-related peptide 1
chr1_-_26293203 0.85 ENSDART00000180140
cxxc4
CXXC finger 4
chr21_+_10828828 0.79 ENSDART00000136449
oacyl
O-acyltransferase like
chr5_-_64883082 0.76 ENSDART00000064983
ENSDART00000139066
krt1-c5
keratin, type 1, gene c5
chr11_-_30636163 0.65 ENSDART00000140516
zgc:153665
zgc:153665
chr22_-_11626014 0.62 ENSDART00000063133
ENSDART00000160085
gcga
glucagon a
chr5_+_38276582 0.59 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr19_-_42556086 0.56 ENSDART00000051731
si:dkey-267n13.1
si:dkey-267n13.1
chr12_-_16595406 0.56 ENSDART00000166798
si:dkey-239j18.2
si:dkey-239j18.2
chr12_-_16595177 0.55 ENSDART00000133962
si:dkey-239j18.2
si:dkey-239j18.2
chr23_+_35672542 0.53 ENSDART00000046268
pmelb
premelanosome protein b
chr11_-_24191928 0.53 ENSDART00000136827
sox12
SRY (sex determining region Y)-box 12
chr1_-_26292897 0.51 ENSDART00000112899
ENSDART00000185410
cxxc4
CXXC finger 4
chr11_-_36350421 0.51 ENSDART00000141477
psma5
proteasome subunit alpha 5
chr19_+_41419519 0.51 ENSDART00000148732
ENSDART00000149799
dlx6a
distal-less homeobox 6a
chr25_-_13703826 0.49 ENSDART00000163398
pla2g15
phospholipase A2, group XV
chr22_-_10541712 0.48 ENSDART00000013933
si:dkey-42i9.4
si:dkey-42i9.4
chr6_-_19351495 0.48 ENSDART00000164287
grb2a
growth factor receptor-bound protein 2a
chr12_+_14079097 0.45 ENSDART00000078033
si:ch211-217a12.1
si:ch211-217a12.1
chr18_-_16801033 0.45 ENSDART00000100100
admb
adrenomedullin b
chr7_-_48667056 0.44 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr4_+_76705830 0.43 ENSDART00000064312
ms4a17a.7
membrane-spanning 4-domains, subfamily A, member 17A.7
chr11_-_7156620 0.43 ENSDART00000172823
ENSDART00000172879
ENSDART00000078916
smim7
small integral membrane protein 7
chr5_+_51594209 0.43 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr17_-_19344999 0.42 ENSDART00000138315
gsc
goosecoid
chr22_-_11623063 0.41 ENSDART00000145653
gcga
glucagon a
chr8_-_40464935 0.41 ENSDART00000040013
myl7
myosin, light chain 7, regulatory
chr15_-_24676211 0.40 ENSDART00000153502
ENSDART00000100756
tmem199
transmembrane protein 199
chr9_+_35016201 0.40 ENSDART00000182404
gabpa
GA binding protein transcription factor, alpha subunit
chr12_-_10476448 0.39 ENSDART00000106172
rac1a
Rac family small GTPase 1a
chr24_-_26328721 0.38 ENSDART00000125468
apodb
apolipoprotein Db
chr25_+_14017609 0.38 ENSDART00000129105
ENSDART00000125733
chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr2_+_7295515 0.38 ENSDART00000152987
si:dkeyp-106c3.1
si:dkeyp-106c3.1
chr17_+_8925232 0.38 ENSDART00000036668
psmc1a
proteasome 26S subunit, ATPase 1a
chr22_-_12763350 0.38 ENSDART00000143574
cnot9
CCR4-NOT transcription complex subunit 9
chr13_-_32726178 0.36 ENSDART00000012232
pdss2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr2_-_38000276 0.36 ENSDART00000034790
pcp4l1
Purkinje cell protein 4 like 1
chr10_+_21588002 0.35 ENSDART00000100596
pcdh1a6
protocadherin 1 alpha 6
chr4_-_72609735 0.35 ENSDART00000174299
ENSDART00000159227
si:cabz01054394.6
si:cabz01054394.6
chr18_-_14691727 0.35 ENSDART00000010129
pdf
peptide deformylase, mitochondrial
chr23_-_40295610 0.35 ENSDART00000186719
CABZ01067002.1

chr17_-_43623356 0.34 ENSDART00000075596
ENSDART00000136431
rtkn2a
rhotekin 2a
chr19_-_1405363 0.33 ENSDART00000165516
cfap20
cilia and flagella associated protein 20
chr19_+_20793237 0.32 ENSDART00000014774
txnl4a
thioredoxin-like 4A
chr3_-_15999501 0.31 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr1_-_55248496 0.31 ENSDART00000098615
nanos3
nanos homolog 3
chr15_+_2534740 0.31 ENSDART00000138469
cux1b
cut-like homeobox 1b
chr5_-_37900350 0.30 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
tmprss13b
transmembrane protease, serine 13b
chr4_+_17279966 0.30 ENSDART00000067005
ENSDART00000137487
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr19_-_3821678 0.30 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr20_-_33507458 0.30 ENSDART00000140287
paplnb
papilin b, proteoglycan-like sulfated glycoprotein
chr7_+_37742299 0.30 ENSDART00000143300
brd7
bromodomain containing 7
chr10_+_20128267 0.29 ENSDART00000064615
dmtn
dematin actin binding protein
chr8_+_4761244 0.29 ENSDART00000137252
ENSDART00000132139
ENSDART00000034968
ENSDART00000143139
ufd1l
ubiquitin recognition factor in ER associated degradation 1
chr4_+_842010 0.29 ENSDART00000067461
si:ch211-152c2.3
si:ch211-152c2.3
chr4_-_17805128 0.29 ENSDART00000128988
spi2
Spi-2 proto-oncogene
chr12_-_44070043 0.29 ENSDART00000180059
si:ch73-329n5.3
si:ch73-329n5.3
chr13_+_28903959 0.28 ENSDART00000166435
si:ch73-28h20.1
si:ch73-28h20.1
chr24_-_8261786 0.28 ENSDART00000106388
eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr24_+_16140423 0.28 ENSDART00000105955
TIMM21
si:dkey-118j18.1
chr1_+_57040472 0.28 ENSDART00000181365
si:ch211-1f22.16
si:ch211-1f22.16
chr7_-_34192834 0.28 ENSDART00000125131
smad6a
SMAD family member 6a
chr2_+_15100742 0.28 ENSDART00000027171
f3b
coagulation factor IIIb
chr8_-_34065573 0.27 ENSDART00000186946
pbx3b
pre-B-cell leukemia homeobox 3b
chr17_+_24615091 0.27 ENSDART00000064739
rpl13a
ribosomal protein L13a
chr2_-_11101329 0.27 ENSDART00000164416
lrrc53
leucine rich repeat containing 53
chr4_-_72544805 0.26 ENSDART00000110261
zgc:175107
zgc:175107
chr6_+_21993613 0.26 ENSDART00000160750
ENSDART00000083070
thumpd3
THUMP domain containing 3
chr22_-_5252005 0.26 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr1_-_38813679 0.26 ENSDART00000148917
asb5b
ankyrin repeat and SOCS box containing 5b
chr3_-_20957011 0.25 ENSDART00000159787
ENSDART00000180531
ndufa4l
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4, like
chr16_-_41465542 0.25 ENSDART00000169116
ENSDART00000187446
cpne4a
copine IVa
chr1_+_580642 0.25 ENSDART00000147633
mrpl39
mitochondrial ribosomal protein L39
chr6_-_54826061 0.25 ENSDART00000149982
tnni1b
troponin I type 1b (skeletal, slow)
chr4_+_76735113 0.25 ENSDART00000075602
ms4a17a.6
membrane-spanning 4-domains, subfamily A, member 17A.6
chr19_-_10330778 0.25 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
ccdc106b
coiled-coil domain containing 106b
chr25_-_24240797 0.25 ENSDART00000132790
spty2d1
SPT2 chromatin protein domain containing 1
chr14_+_48903640 0.25 ENSDART00000165323
zgc:154054
zgc:154054
chr21_-_25623342 0.24 ENSDART00000101201
tmem223
transmembrane protein 223
chr1_-_49950643 0.24 ENSDART00000138301
sgms2
sphingomyelin synthase 2
chr12_-_25150239 0.24 ENSDART00000038415
ENSDART00000135368
rhoq
ras homolog family member Q
chr15_-_4415917 0.24 ENSDART00000062874
atp1b3b
ATPase Na+/K+ transporting subunit beta 3b
chr12_-_33579873 0.24 ENSDART00000184661
tdrkh
tudor and KH domain containing
chr5_-_52752514 0.24 ENSDART00000190162
fam189a2
family with sequence similarity 189, member A2
chr14_-_33978117 0.24 ENSDART00000128515
foxa
forkhead box A sequence
chr10_-_44924289 0.24 ENSDART00000171267
tuba7l
tubulin, alpha 7 like
chr12_+_28986308 0.23 ENSDART00000153178
si:rp71-1c10.8
si:rp71-1c10.8
chr15_+_36309070 0.23 ENSDART00000157034
gmnc
geminin coiled-coil domain containing
chr19_-_3916075 0.23 ENSDART00000161799
si:ch73-281i18.7
si:ch73-281i18.7
chr19_+_7424347 0.23 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr3_-_16000168 0.22 ENSDART00000160628
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr20_-_33497128 0.22 ENSDART00000101974
erh
enhancer of rudimentary homolog (Drosophila)
chr24_+_14595680 0.22 ENSDART00000137337
ENSDART00000091784
ENSDART00000136026
thtpa
thiamine triphosphatase
chr5_+_26795773 0.22 ENSDART00000145631
tcn2
transcobalamin II
chr16_+_31922065 0.22 ENSDART00000131661
ENSDART00000144194
ENSDART00000145510
rps9
ribosomal protein S9
chr15_+_41836104 0.22 ENSDART00000137434
pxylp1
2-phosphoxylose phosphatase 1
chr22_+_12770877 0.22 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr17_+_24623561 0.21 ENSDART00000156734
thumpd2
THUMP domain containing 2
chr3_-_13599482 0.21 ENSDART00000166639
tufm
Tu translation elongation factor, mitochondrial
chr22_+_24220937 0.21 ENSDART00000165380
uchl5
ubiquitin carboxyl-terminal hydrolase L5
chr16_+_33142734 0.21 ENSDART00000138244
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr7_+_31132588 0.21 ENSDART00000173702
tjp1a
tight junction protein 1a
chr18_+_402048 0.21 ENSDART00000166345
gpib
glucose-6-phosphate isomerase b
chr2_-_10877228 0.21 ENSDART00000138718
ENSDART00000034246
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr15_+_17848590 0.21 ENSDART00000168940
zgc:113279
zgc:113279
chr11_+_24900123 0.21 ENSDART00000044987
ENSDART00000148023
timm17a
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr7_+_22981441 0.21 ENSDART00000182887
ccnb3
cyclin B3
chr24_-_27473771 0.21 ENSDART00000139874
cxl34b.11
CX chemokine ligand 34b, duplicate 11
chr4_+_30454496 0.20 ENSDART00000164555
si:dkey-199m13.4
si:dkey-199m13.4
chr15_-_39969988 0.20 ENSDART00000146054
rps5
ribosomal protein S5
chr6_+_37894914 0.20 ENSDART00000148817
oca2
oculocutaneous albinism II
chr10_-_34915886 0.20 ENSDART00000141201
ENSDART00000002166
ccna1
cyclin A1
chr2_+_37750016 0.20 ENSDART00000154726
si:dkeyp-66d1.7
si:dkeyp-66d1.7
chr4_+_17280868 0.20 ENSDART00000145349
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr20_+_36623807 0.20 ENSDART00000149171
ENSDART00000062895
srp9
signal recognition particle 9
chr1_+_26012668 0.20 ENSDART00000182428
BX323448.1

chr9_+_48123224 0.19 ENSDART00000141610
klhl23
kelch-like family member 23
chr10_+_15310811 0.19 ENSDART00000136239
kcnv2a
potassium channel, subfamily V, member 2a
chr20_+_33904258 0.19 ENSDART00000170930
rxrgb
retinoid X receptor, gamma b
chr25_-_173165 0.19 ENSDART00000193594
CABZ01114053.1

chr4_+_76745015 0.19 ENSDART00000155883
ms4a17a.10
membrane-spanning 4-domains, subfamily A, member 17A.10
chr5_-_69707787 0.19 ENSDART00000108820
ENSDART00000149692
dguok
deoxyguanosine kinase
chr9_-_46072805 0.18 ENSDART00000169682
hdac4
histone deacetylase 4
chr2_+_10642047 0.18 ENSDART00000091570
fam69aa
family with sequence similarity 69, member Aa
chr18_-_7382003 0.18 ENSDART00000101238
ENSDART00000178284
bbs10
Bardet-Biedl syndrome 10
chr20_-_38758797 0.18 ENSDART00000061394
trim54
tripartite motif containing 54
chr6_+_72040 0.18 ENSDART00000122957
crygm4
crystallin, gamma M4
chr4_+_7514687 0.18 ENSDART00000067350
ENSDART00000169998
ENSDART00000162082
tnnt2e
troponin T2e, cardiac
chr25_+_22587306 0.17 ENSDART00000067479
stra6
stimulated by retinoic acid 6
chr22_+_13886821 0.17 ENSDART00000130585
ENSDART00000105711
sh3bp4a
SH3-domain binding protein 4a
chr15_+_11427620 0.17 ENSDART00000168688
ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr25_+_3318192 0.17 ENSDART00000146154
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr7_-_26532089 0.17 ENSDART00000121698
senp3b
SUMO1/sentrin/SMT3 specific peptidase 3b
chr23_+_36340520 0.16 ENSDART00000011201
copz1
coatomer protein complex, subunit zeta 1
chr5_+_41143563 0.16 ENSDART00000011229
sub1b
SUB1 homolog, transcriptional regulator b
chr19_-_2420990 0.16 ENSDART00000181498
TMEM196 (1 of many)
transmembrane protein 196
chr15_+_19300230 0.16 ENSDART00000183363
jam3a
junctional adhesion molecule 3a
chr19_+_33139164 0.16 ENSDART00000043039
fam84b
family with sequence similarity 84, member B
chr23_-_4019699 0.16 ENSDART00000159780
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr17_-_24703778 0.16 ENSDART00000156061
si:ch211-15d5.12
si:ch211-15d5.12
chr6_+_11438972 0.16 ENSDART00000029314
col5a2b
collagen, type V, alpha 2b
chr2_-_53525896 0.16 ENSDART00000057053
im:7138239
im:7138239
chr18_-_49318823 0.15 ENSDART00000098419
sb:cb81
sb:cb81
chr23_+_19813677 0.15 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr22_+_25236657 0.15 ENSDART00000138012
zgc:172218
zgc:172218
chr9_-_12888082 0.15 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr7_-_30280934 0.15 ENSDART00000126741
serf2
small EDRK-rich factor 2
chr19_-_31372896 0.15 ENSDART00000046609
scin
scinderin
chr21_-_11286483 0.15 ENSDART00000074845
rtkn2b
rhotekin 2b
chr2_+_1487118 0.14 ENSDART00000147283
c8a
complement component 8, alpha polypeptide
chr25_-_13050959 0.14 ENSDART00000169041
ccl35.1
chemokine (C-C motif) ligand 35, duplicate 1
chr7_+_22657566 0.14 ENSDART00000141048
ponzr5
plac8 onzin related protein 5
chr13_+_45488193 0.14 ENSDART00000188004
tmem50a
transmembrane protein 50A
chr17_+_20205185 0.14 ENSDART00000167007
gnrh3
gonadotropin-releasing hormone 3
chr20_-_18535502 0.14 ENSDART00000049437
cdc42bpb
CDC42 binding protein kinase beta (DMPK-like)
chr17_+_22577472 0.14 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr4_-_65323874 0.14 ENSDART00000175271
ENSDART00000187913
BX571813.1

chr5_+_36666715 0.13 ENSDART00000097686
zgc:153990
zgc:153990
chr21_-_4250682 0.13 ENSDART00000099389
dnlz
DNL-type zinc finger
chr10_+_26827113 0.13 ENSDART00000100301
sssca1
Sjogren syndrome/scleroderma autoantigen 1
chr11_+_24729346 0.13 ENSDART00000087740
zgc:153953
zgc:153953
chr16_-_32008277 0.13 ENSDART00000102133
ENSDART00000141512
gstk4
glutathione S-transferase kappa 4
chr15_+_45640906 0.13 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr9_+_48123002 0.13 ENSDART00000099794
ENSDART00000169733
klhl23
kelch-like family member 23
chr4_-_43280244 0.12 ENSDART00000150762
si:dkeyp-53e4.1
si:dkeyp-53e4.1
chr5_+_30596632 0.12 ENSDART00000051414
hinfp
histone H4 transcription factor
chr4_-_36793658 0.12 ENSDART00000172152
si:dkeyp-87d1.1
si:dkeyp-87d1.1
chr9_-_8296723 0.12 ENSDART00000139867
si:ch211-145c1.1
si:ch211-145c1.1
chr16_-_47427016 0.12 ENSDART00000074575
sept7b
septin 7b
chr17_+_30894431 0.12 ENSDART00000127996
degs2
delta(4)-desaturase, sphingolipid 2
chr17_-_1705013 0.12 ENSDART00000182864
CABZ01086293.1

chr25_+_3788074 0.12 ENSDART00000154008
chid1
chitinase domain containing 1
chr1_+_55752593 0.12 ENSDART00000108838
ENSDART00000134770
tecrb
trans-2,3-enoyl-CoA reductase b
chr5_+_30596477 0.12 ENSDART00000124487
hinfp
histone H4 transcription factor
chr3_-_18189283 0.12 ENSDART00000049240
tob1a
transducer of ERBB2, 1a
chr5_-_24997293 0.11 ENSDART00000177478
emid1
EMI domain containing 1
chr13_+_36680564 0.11 ENSDART00000136030
ENSDART00000006923
atp5s
ATP synthase, H+ transporting, mitochondrial F0 complex subunit s
chr7_-_26627252 0.11 ENSDART00000164050
ENSDART00000159826
phf23b
PHD finger protein 23b
chr11_+_30636351 0.11 ENSDART00000087909
tmem246
transmembrane protein 246
chr17_+_6765621 0.11 ENSDART00000156637
ENSDART00000007622
afg1la
AFG1 like ATPase a
chr7_+_58179513 0.11 ENSDART00000123117
ggh
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr4_-_52621665 0.11 ENSDART00000137064
si:dkeyp-104f11.6
si:dkeyp-104f11.6
chr6_+_10338554 0.11 ENSDART00000186936
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr17_-_43031763 0.11 ENSDART00000132754
ENSDART00000050399
npc2
Niemann-Pick disease, type C2
chr20_+_25911342 0.11 ENSDART00000146004
ttbk2b
tau tubulin kinase 2b
chr5_-_10082244 0.11 ENSDART00000036421
chek2
checkpoint kinase 2
chr19_-_18152407 0.11 ENSDART00000193264
ENSDART00000016135
nfe2l3
nuclear factor, erythroid 2-like 3
chr21_-_27201495 0.11 ENSDART00000145013
zgc:77262
zgc:77262
chr20_-_34985555 0.10 ENSDART00000037065
sccpdhb
saccharopine dehydrogenase b
chr7_+_17947217 0.10 ENSDART00000101601
cth1
cysteine three histidine 1
chr23_+_27352072 0.10 ENSDART00000144762
si:dkey-9p24.5
si:dkey-9p24.5
chr1_-_59169815 0.10 ENSDART00000100163
wu:fk65c09
wu:fk65c09
chr25_+_15647750 0.10 ENSDART00000137375
spon1b
spondin 1b
chr2_+_33747509 0.10 ENSDART00000134187
si:dkey-31m5.5
si:dkey-31m5.5
chr3_-_36419641 0.10 ENSDART00000173545
cog1
component of oligomeric golgi complex 1
chr1_+_27153859 0.10 ENSDART00000180184
bnc2
basonuclin 2
chr5_-_16475374 0.10 ENSDART00000134274
ENSDART00000136004
piwil2
piwi-like RNA-mediated gene silencing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx3-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.5 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.3 GO:0065001 specification of axis polarity(GO:0065001)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.4 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.2 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.1 0.2 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.4 GO:0055014 ventricular cardiac myofibril assembly(GO:0055005) atrial cardiac muscle cell development(GO:0055014)
0.1 0.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0090299 regulation of neural crest formation(GO:0090299)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 0.2 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.3 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.2 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.9 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.1 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.5 GO:0032438 melanosome organization(GO:0032438)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.1 GO:2000638 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.0 0.5 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 0.1 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.2 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 2.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0044364 neutrophil mediated immunity(GO:0002446) killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.4 GO:0007568 aging(GO:0007568)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.1 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.0 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.5 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.0 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.3 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0034246 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.0 0.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 2.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.6 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation