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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr1d2a

Z-value: 1.20

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Transcription factors associated with nr1d2a

Gene Symbol Gene ID Gene Info
nr1d2a
ENSDARG00000003820 nuclear receptor subfamily 1, group D, member 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr1d2adr11_v1_chr16_+_50089417_500894170.923.2e-08Click!

Activity profile of nr1d2a motif

Sorted Z-values of nr1d2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_13244149 4.02 ENSDART00000186984
ENSDART00000105896
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr15_+_19682013 3.94 ENSDART00000127368
si:dkey-4p15.5
si:dkey-4p15.5
chr5_-_11573490 3.62 ENSDART00000109577
FO704871.1

chr17_-_6738538 3.48 ENSDART00000157125
vsnl1b
visinin-like 1b
chr23_+_19564392 3.36 ENSDART00000144746
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr2_+_31804582 3.12 ENSDART00000086646
rnf182
ring finger protein 182
chr3_+_1016404 3.09 ENSDART00000189545
si:ch1073-464p5.5
si:ch1073-464p5.5
chr18_+_907266 3.03 ENSDART00000171729
pkma
pyruvate kinase M1/2a
chr3_+_35298078 3.01 ENSDART00000110126
cacng3b
calcium channel, voltage-dependent, gamma subunit 3b
chr25_+_6306885 2.91 ENSDART00000142705
ENSDART00000067510
crabp1a
cellular retinoic acid binding protein 1a
chr8_-_33114202 2.85 ENSDART00000098840
ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr14_+_17376940 2.82 ENSDART00000054590
ENSDART00000010148
spon2b
spondin 2b, extracellular matrix protein
chr5_-_67878064 2.77 ENSDART00000111203
tagln3a
transgelin 3a
chr19_+_4990320 2.77 ENSDART00000147056
zgc:91968
zgc:91968
chr7_+_65240227 2.66 ENSDART00000168287
bco1l
beta-carotene oxygenase 1, like
chr19_+_4990496 2.60 ENSDART00000151050
ENSDART00000017535
zgc:91968
zgc:91968
chr13_+_29470442 2.59 ENSDART00000028417
lrit2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr15_+_19681718 2.48 ENSDART00000164803
si:dkey-4p15.5
si:dkey-4p15.5
chr20_+_16750177 2.46 ENSDART00000185357
calm1b
calmodulin 1b
chr6_-_39605734 2.23 ENSDART00000044276
ENSDART00000179059
dip2bb
disco-interacting protein 2 homolog Bb
chr22_-_38480186 2.22 ENSDART00000171704
soul4
heme-binding protein soul4
chr12_+_28574863 2.22 ENSDART00000153284
tbkbp1
TBK1 binding protein 1
chr5_-_30079434 2.15 ENSDART00000133981
bco2a
beta-carotene oxygenase 2a
chr20_+_36233873 2.15 ENSDART00000131867
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr24_-_32408404 2.12 ENSDART00000144157
si:ch211-56a11.2
si:ch211-56a11.2
chr15_-_24178893 2.07 ENSDART00000077980
pipox
pipecolic acid oxidase
chr25_+_31264155 2.04 ENSDART00000012256
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr11_+_25430851 1.99 ENSDART00000164999
ENSDART00000126403
si:dkey-13a21.4
si:dkey-13a21.4
chr25_+_14165447 1.94 ENSDART00000145387
shank2
SH3 and multiple ankyrin repeat domains 2
chr12_+_1286642 1.91 ENSDART00000157467
pemt
phosphatidylethanolamine N-methyltransferase
chr16_+_11558868 1.85 ENSDART00000112497
ENSDART00000180445
zgc:198329
zgc:198329
chr2_+_33189582 1.81 ENSDART00000145588
ENSDART00000136330
ENSDART00000139295
ENSDART00000086340
rnf220a
ring finger protein 220a
chr12_-_3756405 1.80 ENSDART00000150839
fam57bb
family with sequence similarity 57, member Bb
chr1_-_30039331 1.77 ENSDART00000086935
ENSDART00000143800
MARCH4 (1 of many)
zgc:153256
chr9_+_13682133 1.76 ENSDART00000175639
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr12_+_12112384 1.75 ENSDART00000152431
grid1b
glutamate receptor, ionotropic, delta 1b
chr23_+_44614056 1.69 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr2_-_16380283 1.67 ENSDART00000149992
si:dkey-231j24.3
si:dkey-231j24.3
chr21_+_40106448 1.58 ENSDART00000100166
serpinf1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_8732037 1.54 ENSDART00000138971
si:ch211-39a7.1
si:ch211-39a7.1
chr20_-_14680897 1.48 ENSDART00000063857
ENSDART00000161314
scrn2
secernin 2
chr21_-_40557281 1.47 ENSDART00000172327
taok1b
TAO kinase 1b
chr7_+_66048102 1.45 ENSDART00000104523
arntl1b
aryl hydrocarbon receptor nuclear translocator-like 1b
chr2_+_20430366 1.45 ENSDART00000155108
si:ch211-153l6.6
si:ch211-153l6.6
chr21_+_27189490 1.43 ENSDART00000125349
bada
BCL2 associated agonist of cell death a
chr25_-_27842654 1.37 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr25_-_1235457 1.37 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr18_+_22302635 1.35 ENSDART00000141051
carmil2
capping protein regulator and myosin 1 linker 2
chr17_+_5793248 1.33 ENSDART00000153743
rp1l1a
retinitis pigmentosa 1-like 1a
chr11_+_30672282 1.33 ENSDART00000023981
ENSDART00000188846
ttbk1a
tau tubulin kinase 1a
chr1_+_9708801 1.33 ENSDART00000189621
elfn1b
extracellular leucine-rich repeat and fibronectin type III domain containing 1b
chr18_-_15559817 1.30 ENSDART00000061681
si:ch211-245j22.3
si:ch211-245j22.3
chr7_-_28058442 1.28 ENSDART00000173842
si:ch211-235p24.2
si:ch211-235p24.2
chr12_-_32183164 1.28 ENSDART00000191269
ENSDART00000173549
SMIM36
si:ch73-256g18.2
chr16_-_24561354 1.28 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr6_+_57541776 1.26 ENSDART00000157330
necab3
N-terminal EF-hand calcium binding protein 3
chr8_-_18899427 1.18 ENSDART00000079840
rorca
RAR-related orphan receptor C a
chr7_-_2047639 1.11 ENSDART00000173892
si:cabz01007794.1
si:cabz01007794.1
chr22_+_21317597 1.08 ENSDART00000132605
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr19_+_2590182 1.07 ENSDART00000162293
si:ch73-345f18.3
si:ch73-345f18.3
chr25_+_20188769 1.04 ENSDART00000142781
cald1b
caldesmon 1b
chr15_+_2559875 1.02 ENSDART00000178505
SH2B2
SH2B adaptor protein 2
chr15_+_42599501 0.99 ENSDART00000177646
grik1b
glutamate receptor, ionotropic, kainate 1b
chr12_-_32013125 0.99 ENSDART00000153355
grin2cb
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr9_+_35876927 0.99 ENSDART00000138834
mab21l3
mab-21-like 3
chr8_-_3773374 0.99 ENSDART00000115036
bicdl1
BICD family like cargo adaptor 1
chr19_-_15335787 0.99 ENSDART00000187131
hivep3a
human immunodeficiency virus type I enhancer binding protein 3a
chr23_-_44233408 0.97 ENSDART00000149318
ENSDART00000085528
zgc:158659
zgc:158659
chr2_+_30721070 0.97 ENSDART00000099052
si:dkey-94e7.2
si:dkey-94e7.2
chr2_-_56655769 0.95 ENSDART00000113589
gpx4b
glutathione peroxidase 4b
chr1_+_55752593 0.93 ENSDART00000108838
ENSDART00000134770
tecrb
trans-2,3-enoyl-CoA reductase b
chr1_-_44704261 0.91 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr18_+_7594012 0.90 ENSDART00000062150
zgc:77752
zgc:77752
chr17_+_20174044 0.88 ENSDART00000156028
si:ch211-248a14.8
si:ch211-248a14.8
chr25_-_27843066 0.85 ENSDART00000179684
ENSDART00000186000
ENSDART00000190065
asb15a
ankyrin repeat and SOCS box containing 15a
chr18_-_39473055 0.84 ENSDART00000122930
scg3
secretogranin III
chr10_+_2232023 0.84 ENSDART00000097695
cntnap3
contactin associated protein like 3
chr22_+_17828267 0.84 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr16_+_30438041 0.82 ENSDART00000137977
pear1
platelet endothelial aggregation receptor 1
chr6_+_32415132 0.78 ENSDART00000155790
kank4
KN motif and ankyrin repeat domains 4
chr9_-_48937089 0.77 ENSDART00000193442
cers6
ceramide synthase 6
chr18_-_35736591 0.76 ENSDART00000036015
ryr1b
ryanodine receptor 1b (skeletal)
chr18_-_42313798 0.75 ENSDART00000098639
cntn5
contactin 5
chr24_+_24809877 0.74 ENSDART00000185117
dnajc5b
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr6_+_37752781 0.71 ENSDART00000154364
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr22_-_29689485 0.71 ENSDART00000182173
pdcd4b
programmed cell death 4b
chr3_-_2592350 0.70 ENSDART00000192325
si:dkey-217f16.5
si:dkey-217f16.5
chr12_+_19305390 0.66 ENSDART00000183987
ENSDART00000066391
csnk1e
casein kinase 1, epsilon
chr11_-_21303946 0.64 ENSDART00000185786
RASSF5
si:dkey-85p17.3
chr17_-_7371564 0.58 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr17_+_6625717 0.56 ENSDART00000190753
ENSDART00000181298
BX005321.1

chr9_-_8661436 0.52 ENSDART00000130442
col4a1
collagen, type IV, alpha 1
chr8_+_42917515 0.50 ENSDART00000021715
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr1_-_21297748 0.46 ENSDART00000142109
npy1r
neuropeptide Y receptor Y1
chr21_+_30549512 0.45 ENSDART00000132831
rab38c
RAB38c, member of RAS oncogene family
chr3_-_2591942 0.45 ENSDART00000127971
si:dkey-217f16.5
si:dkey-217f16.5
chr5_-_35888499 0.43 ENSDART00000193932
rxfp2l
relaxin/insulin-like family peptide receptor 2, like
chr6_-_21726758 0.42 ENSDART00000083085
mtmr14
myotubularin related protein 14
chr3_+_60761811 0.42 ENSDART00000053482
tsen54
TSEN54 tRNA splicing endonuclease subunit
chr9_+_17982737 0.41 ENSDART00000192569
akap11
A kinase (PRKA) anchor protein 11
chr8_+_18464235 0.40 ENSDART00000110571
alkal1
ALK and LTK ligand 1
chr19_+_30990129 0.40 ENSDART00000052169
ENSDART00000193376
sync
syncoilin, intermediate filament protein
chr4_-_22519516 0.39 ENSDART00000130409
ENSDART00000186258
ENSDART00000002851
ENSDART00000123801
kdm7aa
lysine (K)-specific demethylase 7Aa
chr19_+_30990815 0.38 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr12_+_7399403 0.36 ENSDART00000103526
bicc1b
BicC family RNA binding protein 1b
chr5_+_38743644 0.35 ENSDART00000137658
si:dkey-58f10.6
si:dkey-58f10.6
chr1_-_49498116 0.35 ENSDART00000137357
zgc:175214
zgc:175214
chr18_+_27738349 0.35 ENSDART00000187816
tspan18b
tetraspanin 18b
chr15_-_34322915 0.34 ENSDART00000190543
ENSDART00000019651
ENSDART00000193601
dgkb
diacylglycerol kinase, beta
chr2_-_42558549 0.34 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr17_-_15528597 0.34 ENSDART00000150232
fyna
FYN proto-oncogene, Src family tyrosine kinase a
chr11_-_21304452 0.34 ENSDART00000163008
RASSF5
si:dkey-85p17.3
chr23_+_41831224 0.33 ENSDART00000171885
scp2b
sterol carrier protein 2b
chr23_-_5729484 0.33 ENSDART00000000488
tnni1a
troponin I type 1a (skeletal, slow)
chr3_-_16039619 0.32 ENSDART00000143324
spsb3a
splA/ryanodine receptor domain and SOCS box containing 3a
chr25_-_17918810 0.32 ENSDART00000023959
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr22_-_6849585 0.32 ENSDART00000125750
FO904898.1

chr3_+_57997980 0.31 ENSDART00000168477
ENSDART00000193840
pycr1a
pyrroline-5-carboxylate reductase 1a
chr12_+_30789611 0.31 ENSDART00000181501
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr6_-_8244474 0.26 ENSDART00000151358
rgl3a
ral guanine nucleotide dissociation stimulator-like 3a
chr21_-_2209012 0.25 ENSDART00000158345
zgc:162971
zgc:162971
chr5_+_43470544 0.25 ENSDART00000111587
rhobtb2a
Rho-related BTB domain containing 2a
chr16_+_8716800 0.22 ENSDART00000124693
ENSDART00000181961
cabz01093075.1
cabz01093075.1
chr11_+_19159083 0.20 ENSDART00000138964
adamts9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr23_-_36003282 0.19 ENSDART00000103150
calcoco1a
calcium binding and coiled-coil domain 1a
chr20_+_44082532 0.19 ENSDART00000188481
BX510352.1

chr8_+_14158021 0.18 ENSDART00000080832
si:dkey-6n6.2
si:dkey-6n6.2
chr22_-_23000815 0.17 ENSDART00000137111
ptprc
protein tyrosine phosphatase, receptor type, C
chr12_+_9542124 0.17 ENSDART00000127952
p4ha1a
prolyl 4-hydroxylase, alpha polypeptide I a
chr13_+_30172645 0.16 ENSDART00000137114
pald1b
phosphatase domain containing, paladin 1b
chr8_+_18463797 0.14 ENSDART00000148958
alkal1
ALK and LTK ligand 1
chr8_+_43340995 0.13 ENSDART00000038566
rflna
refilin A
chr3_+_32698424 0.12 ENSDART00000055340
fus
FUS RNA binding protein
chr1_+_15204633 0.12 ENSDART00000188410
itln1
intelectin 1
chr22_+_36704764 0.12 ENSDART00000146662
trim35-33
tripartite motif containing 35-33
chr9_+_28116079 0.11 ENSDART00000101338
idh1
isocitrate dehydrogenase 1 (NADP+), soluble
chr15_+_17100412 0.11 ENSDART00000154418
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr8_+_21146262 0.10 ENSDART00000045684
porcn
porcupine O-acyltransferase
chr15_-_31419805 0.10 ENSDART00000060111
or111-11
odorant receptor, family D, subfamily 111, member 11
chr1_+_26667872 0.10 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemgn
hemogen
chr14_-_24001825 0.08 ENSDART00000130704
il4
interleukin 4
chr6_-_31364475 0.07 ENSDART00000145715
ENSDART00000134370
ak4
adenylate kinase 4
chr7_+_22705656 0.07 ENSDART00000193008
si:dkey-165a24.9
si:dkey-165a24.9
chr20_+_46620374 0.06 ENSDART00000005548
batf
basic leucine zipper transcription factor, ATF-like
chr1_-_33353778 0.05 ENSDART00000041191
gyg2
glycogenin 2
chr15_-_34878388 0.04 ENSDART00000154094
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr12_+_804314 0.03 ENSDART00000082169
wfikkn2b
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b
chr25_-_19219807 0.03 ENSDART00000183577
acanb
aggrecan b
chr8_+_21225064 0.03 ENSDART00000129210
cry1ba
cryptochrome circadian clock 1ba
chr20_+_46202188 0.02 ENSDART00000100523
taar13c
trace amine associated receptor 13c
chr4_+_7876197 0.02 ENSDART00000111986
ENSDART00000189601
cdc123
cell division cycle 123 homolog (S. cerevisiae)
chr3_-_26190804 0.01 ENSDART00000136001
ypel3
yippee-like 3
chr18_+_6162194 0.01 ENSDART00000177153
otogl
otogelin-like
chr15_+_17100697 0.00 ENSDART00000183565
ENSDART00000123197
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B

Network of associatons between targets according to the STRING database.

First level regulatory network of nr1d2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.5 4.8 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.5 2.1 GO:0006554 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.5 7.4 GO:0090382 phagosome maturation(GO:0090382)
0.2 1.0 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.2 1.9 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 1.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 1.3 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 3.0 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.2 0.5 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.2 0.8 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 1.3 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 2.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.3 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.5 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1 1.0 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.6 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.3 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.1 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 2.8 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.1 3.4 GO:0030641 regulation of cellular pH(GO:0030641)
0.1 1.0 GO:0032438 melanosome organization(GO:0032438)
0.1 3.0 GO:0006096 glycolytic process(GO:0006096)
0.1 2.1 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.1 1.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 1.5 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0061037 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.4 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 1.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 2.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.7 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 4.9 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.3 GO:0035082 axoneme assembly(GO:0035082)
0.0 2.3 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.1 GO:0042832 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0 1.1 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 1.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.5 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 1.0 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.4 5.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 5.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 4.0 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 2.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 5.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.5 GO:0009986 cell surface(GO:0009986)
0.0 2.2 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.8 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.5 3.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.4 2.9 GO:0001972 retinoic acid binding(GO:0001972)
0.3 2.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3 1.5 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.3 4.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 2.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 0.8 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 1.0 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.5 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 1.0 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 2.7 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 6.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 3.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 5.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.2 GO:0020037 heme binding(GO:0020037)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation