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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr3c1_ar

Z-value: 2.35

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Transcription factors associated with nr3c1_ar

Gene Symbol Gene ID Gene Info
nr3c1
ENSDARG00000025032 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
nr3c1
ENSDARG00000112480 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
nr3c1
ENSDARG00000116957 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ar
ENSDARG00000067976 androgen receptor
ar
ENSDARG00000114287 androgen receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr3c1dr11_v1_chr14_-_23801389_23801389-0.854.0e-06Click!
ardr11_v1_chr5_+_35561607_355616070.512.4e-02Click!

Activity profile of nr3c1_ar motif

Sorted Z-values of nr3c1_ar motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41096058 17.94 ENSDART00000028373
fkbp5
FK506 binding protein 5
chr6_+_41099787 12.86 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr12_+_13256415 12.41 ENSDART00000144542
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr3_-_31079186 10.83 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr17_-_37395460 10.20 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr16_+_50089417 7.98 ENSDART00000153675
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr24_-_38097305 7.78 ENSDART00000124321
crp2
C-reactive protein 2
chr6_-_46875310 7.66 ENSDART00000154442
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr5_-_24238733 5.94 ENSDART00000138170
plscr3a
phospholipid scramblase 3a
chr15_-_9031996 5.91 ENSDART00000124998
rtn2a
reticulon 2a
chr16_+_10777116 5.64 ENSDART00000190902
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr17_-_6730247 5.54 ENSDART00000031091
vsnl1b
visinin-like 1b
chr2_+_52232630 5.49 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr12_-_4683325 5.37 ENSDART00000152771
si:ch211-255p10.3
si:ch211-255p10.3
chr10_+_29431529 5.37 ENSDART00000158154
dlg2
discs, large homolog 2 (Drosophila)
chr2_-_22688651 5.37 ENSDART00000013863
agxtb
alanine-glyoxylate aminotransferase b
chr5_+_9382301 5.33 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr16_+_10776688 5.27 ENSDART00000161969
ENSDART00000172657
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr14_-_46228094 5.11 ENSDART00000172788
si:ch211-113d11.5
si:ch211-113d11.5
chr10_-_24343507 5.11 ENSDART00000002974
pitpnab
phosphatidylinositol transfer protein, alpha b
chr18_-_24996634 4.97 ENSDART00000170210
si:ch211-196l7.4
si:ch211-196l7.4
chr7_+_48288762 4.96 ENSDART00000083569
oaz2b
ornithine decarboxylase antizyme 2b
chr22_-_968484 4.89 ENSDART00000105895
cacna1sa
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr20_-_791788 4.76 ENSDART00000134128
impg1a
interphotoreceptor matrix proteoglycan 1a
chr21_+_6290566 4.53 ENSDART00000161647
fnbp1b
formin binding protein 1b
chr2_-_155270 4.44 ENSDART00000131177
adcy1b
adenylate cyclase 1b
chr5_+_9360394 4.34 ENSDART00000124642
FP236810.2

chr14_-_2355833 4.31 ENSDART00000157677
PCDHGC3 (1 of many)
si:ch73-233f7.6
chr9_-_9977827 4.29 ENSDART00000187315
ENSDART00000010246
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr19_+_19412692 4.19 ENSDART00000113580
wu:fc38h03
wu:fc38h03
chr7_+_58699718 4.09 ENSDART00000049264
sdr16c5b
short chain dehydrogenase/reductase family 16C, member 5b
chr9_-_9982696 4.08 ENSDART00000192548
ENSDART00000125852
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr1_-_26782573 3.89 ENSDART00000090611
sh3gl2a
SH3 domain containing GRB2 like 2a, endophilin A1
chr14_+_32838110 3.65 ENSDART00000158077
arr3b
arrestin 3b, retinal (X-arrestin)
chr8_+_53452681 3.54 ENSDART00000166705
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr11_+_6152643 3.48 ENSDART00000012789
slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr2_+_38556195 3.45 ENSDART00000138769
cdh24b
cadherin 24, type 2b
chr3_-_5067585 3.43 ENSDART00000169609
tefb
thyrotrophic embryonic factor b
chr16_+_46430627 3.37 ENSDART00000127681
rpz6
rapunzel 6
chr21_+_25054420 3.35 ENSDART00000065132
zgc:171740
zgc:171740
chr11_+_34522554 3.32 ENSDART00000109833
zmat3
zinc finger, matrin-type 3
chr7_-_32833153 3.15 ENSDART00000099871
ENSDART00000099872
slc17a6b
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr3_-_32337653 3.13 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr12_-_46959990 3.12 ENSDART00000084557
lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr14_-_2036604 3.12 ENSDART00000192446
BX005294.2

chr5_-_5669879 3.07 ENSDART00000191963
CABZ01075628.1

chr15_-_24883956 2.99 ENSDART00000113199
aipl1
aryl hydrocarbon receptor interacting protein-like 1
chr4_-_2014406 2.96 ENSDART00000180463
si:dkey-97m3.1
si:dkey-97m3.1
chr9_+_22677503 2.95 ENSDART00000131429
ENSDART00000080005
ENSDART00000101756
ENSDART00000138148
itgb5
integrin, beta 5
chr5_-_37116265 2.86 ENSDART00000057613
il13ra2
interleukin 13 receptor, alpha 2
chr21_+_6291027 2.83 ENSDART00000180467
ENSDART00000184952
ENSDART00000184006
fnbp1b
formin binding protein 1b
chr4_-_38507880 2.82 ENSDART00000183225
si:ch211-209n20.3
si:ch211-209n20.3
chr4_+_25651720 2.79 ENSDART00000100693
ENSDART00000100717
acot16
acyl-CoA thioesterase 16
chr13_+_912123 2.77 ENSDART00000169931
pcsk2
proprotein convertase subtilisin/kexin type 2
chr18_+_17428258 2.73 ENSDART00000010452
zgc:91860
zgc:91860
chr20_+_54336137 2.72 ENSDART00000113792
cipcb
CLOCK-interacting pacemaker b
chr15_+_37559570 2.72 ENSDART00000085522
hspb6
heat shock protein, alpha-crystallin-related, b6
chr21_-_30648106 2.67 ENSDART00000160800
ENSDART00000177022
phka1b
phosphorylase kinase, alpha 1b (muscle)
chr18_+_50278858 2.66 ENSDART00000014582
si:dkey-105e17.1
si:dkey-105e17.1
chr6_-_27123327 2.65 ENSDART00000073881
agxta
alanine-glyoxylate aminotransferase a
chr1_+_51615672 2.64 ENSDART00000165117
zgc:165656
zgc:165656
chr5_+_51594209 2.61 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr10_-_24689725 2.61 ENSDART00000079566
si:ch211-287a12.9
si:ch211-287a12.9
chr21_+_1378250 2.60 ENSDART00000186912
TCF4
transcription factor 4
chr20_-_9273669 2.56 ENSDART00000175069
syt14b
synaptotagmin XIVb
chr16_-_22781446 2.54 ENSDART00000144107
lenep
lens epithelial protein
chr8_+_7359294 2.51 ENSDART00000121708
pcsk1nl
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr10_+_375042 2.49 ENSDART00000171854
si:ch1073-303d10.1
si:ch1073-303d10.1
chr18_+_8346920 2.49 ENSDART00000083421
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr1_-_59176949 2.46 ENSDART00000128742
CABZ01118678.1

chr22_+_37874691 2.43 ENSDART00000028565
ahsg1
alpha-2-HS-glycoprotein 1
chr12_+_16440708 2.42 ENSDART00000113810
ankrd1b
ankyrin repeat domain 1b (cardiac muscle)
chr20_+_28266892 2.39 ENSDART00000103330
chac1
ChaC, cation transport regulator homolog 1 (E. coli)
chr10_-_17988779 2.39 ENSDART00000132206
ENSDART00000144841
si:dkey-242g16.2
si:dkey-242g16.2
chr20_-_34801181 2.33 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr19_-_205104 2.31 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr8_-_13315567 2.29 ENSDART00000132685
ENSDART00000168635
kcnn1b
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b
chr5_-_23362602 2.29 ENSDART00000137120
gria3a
glutamate receptor, ionotropic, AMPA 3a
chr22_-_16400484 2.29 ENSDART00000135987
lama3
laminin, alpha 3
chr9_+_23009608 2.29 ENSDART00000079879
si:dkey-91i10.3
si:dkey-91i10.3
chr7_-_29340427 2.27 ENSDART00000052584
trpm1a
transient receptor potential cation channel, subfamily M, member 1a
chr20_+_39283849 2.27 ENSDART00000002481
ENSDART00000146683
scara3
scavenger receptor class A, member 3
chr4_-_11163112 2.25 ENSDART00000188854
prmt8b
protein arginine methyltransferase 8b
chr4_-_73709502 2.25 ENSDART00000170308
BX855614.3

chr19_-_32804535 2.23 ENSDART00000175613
ENSDART00000052098
nt5c1aa
5'-nucleotidase, cytosolic IAa
chr16_-_22225295 2.21 ENSDART00000163519
LO017682.1

chr24_-_24271629 2.21 ENSDART00000135060
rps6ka3b
ribosomal protein S6 kinase, polypeptide 3b
chr1_+_19433004 2.16 ENSDART00000133959
clockb
clock circadian regulator b
chr2_+_13056802 2.14 ENSDART00000142649
prkag2b
protein kinase, AMP-activated, gamma 2 non-catalytic subunit b
chr9_-_22076368 2.13 ENSDART00000128486
crygm2a
crystallin, gamma M2a
chr25_+_10416583 2.10 ENSDART00000073907
ehf
ets homologous factor
chr4_-_20043484 2.09 ENSDART00000167780
zgc:193726
zgc:193726
chr16_+_19677484 2.08 ENSDART00000150588
tmem196b
transmembrane protein 196b
chr20_-_3166168 2.07 ENSDART00000134137
si:ch73-212j7.3
si:ch73-212j7.3
chr8_-_37263524 2.06 ENSDART00000061327
rh50
Rh50-like protein
chr5_-_41494831 2.04 ENSDART00000051081
eef2l2
eukaryotic translation elongation factor 2, like 2
chr12_+_19401854 2.04 ENSDART00000153415
si:dkey-16i5.8
si:dkey-16i5.8
chr6_+_40354424 2.03 ENSDART00000047416
slc4a8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr5_+_28830643 2.03 ENSDART00000051448
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr8_-_13315304 2.02 ENSDART00000142596
kcnn1b
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b
chr24_-_38110779 2.01 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr2_+_25929619 2.01 ENSDART00000137746
slc7a14a
solute carrier family 7, member 14a
chr3_-_60571218 1.99 ENSDART00000178981
si:ch73-366l1.5
si:ch73-366l1.5
chr4_-_19921410 1.96 ENSDART00000184359
ENSDART00000179965
BX323820.1

chr23_-_1557195 1.95 ENSDART00000136436
epm2a
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr10_+_41765944 1.92 ENSDART00000171484
rnf34b
ring finger protein 34b
chr5_-_15524782 1.91 ENSDART00000189781
CU694999.1

chr8_-_50525360 1.90 ENSDART00000175648
CABZ01060030.1

chr4_-_789645 1.90 ENSDART00000164441
mapre3b
microtubule-associated protein, RP/EB family, member 3b
chr8_+_8459192 1.89 ENSDART00000140942
ENSDART00000014939
comta
catechol-O-methyltransferase a
chr7_-_30087048 1.88 ENSDART00000112743
nmbb
neuromedin Bb
chr6_+_4255319 1.85 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr20_-_6812688 1.84 ENSDART00000170934
igfbp1a
insulin-like growth factor binding protein 1a
chr5_+_9417409 1.84 ENSDART00000125421
ENSDART00000130265
ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr17_-_277046 1.82 ENSDART00000182587
LO018437.1

chr7_+_18364176 1.80 ENSDART00000171606
ENSDART00000186368
cd248a
CD248 molecule, endosialin a
chr5_+_32206378 1.79 ENSDART00000126873
ENSDART00000051361
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr11_+_34523132 1.77 ENSDART00000192257
zmat3
zinc finger, matrin-type 3
chr23_+_9088191 1.76 ENSDART00000030811
cables2b
Cdk5 and Abl enzyme substrate 2b
chr3_+_55288200 1.73 ENSDART00000157002
ENSDART00000155600
si:dkey-114l24.2
si:dkey-114l24.2
chr23_+_37444933 1.72 ENSDART00000074385
AL954146.1

chr17_-_45247151 1.70 ENSDART00000186230
ttbk2a
tau tubulin kinase 2a
chr10_-_16868211 1.70 ENSDART00000171755
stoml2
stomatin (EPB72)-like 2
chr3_-_48716422 1.69 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr7_-_18168493 1.68 ENSDART00000127428
peli3
pellino E3 ubiquitin protein ligase family member 3
chr20_-_29475172 1.67 ENSDART00000183164
scg5
secretogranin V
chr8_-_46700278 1.66 ENSDART00000143780
gpr153
G protein-coupled receptor 153
chr15_-_12011202 1.64 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
si:dkey-202l22.6
chr21_-_131236 1.62 ENSDART00000160005
si:ch1073-398f15.1
si:ch1073-398f15.1
chr10_+_34315719 1.60 ENSDART00000135303
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr21_+_30563115 1.59 ENSDART00000028566
si:ch211-200p22.4
si:ch211-200p22.4
chr3_-_35800221 1.58 ENSDART00000031390
caskin1
CASK interacting protein 1
chr3_-_50124413 1.58 ENSDART00000189920
cldnk
claudin k
chr11_+_11175814 1.56 ENSDART00000183864
CR847973.1

chr7_+_18017756 1.55 ENSDART00000173717
ehbp1l1a
EH domain binding protein 1-like 1a
chr11_-_19097746 1.55 ENSDART00000103973
rhol
rhodopsin, like
chr10_+_33754967 1.54 ENSDART00000153442
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr7_+_6969909 1.54 ENSDART00000189886
actn3b
actinin alpha 3b
chr22_+_26813917 1.52 ENSDART00000147719
slx4
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr17_-_32698503 1.47 ENSDART00000157175
ENSDART00000077439
kcnk2a
potassium channel, subfamily K, member 2a
chr6_-_8580857 1.47 ENSDART00000138858
ENSDART00000041142
myh11a
myosin, heavy chain 11a, smooth muscle
chr11_+_37144328 1.47 ENSDART00000162830
wnk2
WNK lysine deficient protein kinase 2
chr12_-_44151296 1.47 ENSDART00000168734
si:ch73-329n5.3
si:ch73-329n5.3
chr24_+_35564668 1.46 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr4_+_19534833 1.46 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr9_+_45428041 1.46 ENSDART00000193087
adarb1b
adenosine deaminase, RNA-specific, B1b
chr4_-_2162688 1.41 ENSDART00000148900
kcnc2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr13_+_13821054 1.41 ENSDART00000127417
slc4a11
solute carrier family 4, sodium borate transporter, member 11
chr24_+_13316737 1.40 ENSDART00000191658
SBSPON
somatomedin B and thrombospondin type 1 domain containing
chr18_-_35736591 1.38 ENSDART00000036015
ryr1b
ryanodine receptor 1b (skeletal)
chr16_-_50175069 1.38 ENSDART00000192979
lim2.5
lens intrinsic membrane protein 2.5
chr23_+_44732863 1.36 ENSDART00000160044
ENSDART00000172268
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr1_-_55008882 1.36 ENSDART00000083572
zgc:136864
zgc:136864
chr11_-_34147205 1.33 ENSDART00000173216
atp13a3
ATPase 13A3
chr18_+_17428506 1.32 ENSDART00000100223
zgc:91860
zgc:91860
chr15_-_12011390 1.32 ENSDART00000187403
si:dkey-202l22.6
si:dkey-202l22.6
chr15_-_23908605 1.30 ENSDART00000185578
usp32
ubiquitin specific peptidase 32
chr1_-_1631399 1.29 ENSDART00000176787
clic6
chloride intracellular channel 6
chr4_+_76735113 1.29 ENSDART00000075602
ms4a17a.6
membrane-spanning 4-domains, subfamily A, member 17A.6
chr2_-_48396061 1.28 ENSDART00000161657
si:ch211-195j11.30
si:ch211-195j11.30
chr25_-_29363934 1.28 ENSDART00000166889
nptna
neuroplastin a
chr23_+_4583747 1.28 ENSDART00000160350
LO017700.1

chr2_+_47708853 1.27 ENSDART00000124307
mbnl1
muscleblind-like splicing regulator 1
chr11_-_7050825 1.26 ENSDART00000179749
si:ch211-253b8.5
si:ch211-253b8.5
chr13_-_37619159 1.26 ENSDART00000186348
zgc:152791
zgc:152791
chr17_+_45737992 1.25 ENSDART00000135073
ENSDART00000143525
ENSDART00000158165
ENSDART00000184167
ENSDART00000109525
aspg
asparaginase homolog (S. cerevisiae)
chr10_+_37500234 1.24 ENSDART00000132096
ENSDART00000099473
msi2a
musashi RNA-binding protein 2a
chr12_+_32073660 1.22 ENSDART00000153245
ENSDART00000153268
stxbp4
syntaxin binding protein 4
chr24_-_9960290 1.21 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vps41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr9_+_42157578 1.18 ENSDART00000142888
lrrc3
leucine rich repeat containing 3
chr5_+_32162684 1.17 ENSDART00000134472
taok3b
TAO kinase 3b
chr17_-_45552602 1.16 ENSDART00000154844
ENSDART00000034432
susd4
sushi domain containing 4
chr2_+_30144979 1.16 ENSDART00000129365
ENSDART00000130344
kcnb2
potassium voltage-gated channel, Shab-related subfamily, member 2
chr5_+_70345518 1.15 ENSDART00000167029
pappaa
pregnancy-associated plasma protein A, pappalysin 1a
chr3_+_20012891 1.15 ENSDART00000078974
tmub2
transmembrane and ubiquitin-like domain containing 2
chr3_-_36440705 1.14 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr5_+_28830388 1.14 ENSDART00000149150
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr7_+_53152108 1.14 ENSDART00000171350
cdh29
cadherin 29
chr20_+_34915945 1.14 ENSDART00000153064
snap25a
synaptosomal-associated protein, 25a
chr17_+_29345606 1.14 ENSDART00000086164
kctd3
potassium channel tetramerization domain containing 3
chr13_+_4505232 1.13 ENSDART00000007500
ENSDART00000161684
pde10a
phosphodiesterase 10A
chr3_+_53228684 1.13 ENSDART00000156490
pet100
PET100 homolog
chr23_+_23183449 1.13 ENSDART00000132296
klhl17
kelch-like family member 17
chr17_+_23578316 1.13 ENSDART00000149281
slc16a12a
solute carrier family 16, member 12a
chr5_+_65536095 1.12 ENSDART00000189898
si:dkey-21e5.1
si:dkey-21e5.1
chr8_-_45835056 1.12 ENSDART00000022242
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr25_+_19149241 1.12 ENSDART00000184982
ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr10_+_26667475 1.12 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
si:ch73-52f15.5
chr1_+_32521469 1.11 ENSDART00000113818
ENSDART00000152580
nlgn4a
neuroligin 4a
chr17_+_6276559 1.11 ENSDART00000131075
dusp23b
dual specificity phosphatase 23b
chr19_-_41213718 1.09 ENSDART00000077121
pdk4
pyruvate dehydrogenase kinase, isozyme 4
chr8_+_31777633 1.08 ENSDART00000142519
oxct1a
3-oxoacid CoA transferase 1a
chr1_-_48922273 1.08 ENSDART00000150254
si:ch211-112b1.2
si:ch211-112b1.2
chr3_-_35602233 1.07 ENSDART00000055269
gng13b
guanine nucleotide binding protein (G protein), gamma 13b
chr23_+_6752828 1.06 ENSDART00000105179
zgc:158254
zgc:158254
chr7_-_19168375 1.06 ENSDART00000112447
il13ra1
interleukin 13 receptor, alpha 1
chr13_-_11378355 1.06 ENSDART00000164566
akt3a
v-akt murine thymoma viral oncogene homolog 3a
chr9_-_21918963 1.05 ENSDART00000090782
lmo7a
LIM domain 7a
chr5_-_3627110 1.05 ENSDART00000156071
si:zfos-375h5.1
si:zfos-375h5.1
chr3_-_58543658 1.03 ENSDART00000042386
unm_sa1261
un-named sa1261

Network of associatons between targets according to the STRING database.

First level regulatory network of nr3c1_ar

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
1.3 8.0 GO:0006545 glycine biosynthetic process(GO:0006545)
1.0 30.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.8 5.3 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.7 2.7 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.6 12.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.5 2.3 GO:0060401 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.4 1.7 GO:0099563 modification of synaptic structure(GO:0099563)
0.4 8.5 GO:0006825 copper ion transport(GO:0006825)
0.4 2.0 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.4 3.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.4 1.2 GO:0006957 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
0.4 1.5 GO:0061010 gall bladder development(GO:0061010)
0.3 1.7 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.3 4.4 GO:0016199 axon midline choice point recognition(GO:0016199)
0.3 1.4 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.3 1.9 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.3 2.4 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.2 5.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 11.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 3.1 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 0.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 1.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 2.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 1.9 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 3.0 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2 10.3 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.2 0.8 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.2 0.6 GO:0001562 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.2 2.8 GO:0016486 peptide hormone processing(GO:0016486)
0.2 5.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 4.2 GO:0006595 polyamine metabolic process(GO:0006595)
0.2 2.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 1.5 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.2 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 0.8 GO:0014005 microglia development(GO:0014005)
0.2 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 3.2 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 2.5 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 2.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 1.5 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 1.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 0.5 GO:0097037 heme export(GO:0097037)
0.1 1.9 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.1 0.2 GO:2000108 positive regulation of leukocyte apoptotic process(GO:2000108)
0.1 3.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 6.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.7 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.8 GO:0030431 sleep(GO:0030431)
0.1 0.5 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 1.1 GO:0050909 sensory perception of taste(GO:0050909)
0.1 22.3 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 2.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0006788 heme oxidation(GO:0006788)
0.1 2.6 GO:0046883 regulation of hormone secretion(GO:0046883)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.1 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 4.8 GO:0015914 phospholipid transport(GO:0015914)
0.1 1.5 GO:0014823 response to activity(GO:0014823)
0.1 0.6 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.5 GO:0045905 positive regulation of translational termination(GO:0045905)
0.1 2.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 1.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.3 GO:1903405 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 1.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 4.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.1 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 1.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.4 GO:0050957 neuromuscular process controlling balance(GO:0050885) equilibrioception(GO:0050957)
0.0 0.7 GO:0099645 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.8 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0010165 response to X-ray(GO:0010165)
0.0 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.7 GO:0048016 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 1.1 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 2.1 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.3 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.0 9.6 GO:0007601 visual perception(GO:0007601)
0.0 0.5 GO:0097369 sodium ion import(GO:0097369) inorganic cation import into cell(GO:0098659) sodium ion import across plasma membrane(GO:0098719) inorganic ion import into cell(GO:0099587) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 2.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.5 GO:0035094 response to nicotine(GO:0035094)
0.0 2.0 GO:0006414 translational elongation(GO:0006414)
0.0 1.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 8.1 GO:0009617 response to bacterium(GO:0009617)
0.0 0.5 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 1.6 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 5.7 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0044209 AMP salvage(GO:0044209)
0.0 2.3 GO:0016358 dendrite development(GO:0016358)
0.0 1.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 1.7 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.3 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.8 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.4 GO:0042574 retinal metabolic process(GO:0042574)
0.0 6.5 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.4 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.1 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.3 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 3.9 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 1.1 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.6 GO:0001503 ossification(GO:0001503)
0.0 1.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993)
0.0 0.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.9 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 2.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0046633 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) alpha-beta T cell proliferation(GO:0046633) regulation of alpha-beta T cell activation(GO:0046634) negative regulation of alpha-beta T cell activation(GO:0046636) regulation of alpha-beta T cell proliferation(GO:0046640) negative regulation of alpha-beta T cell proliferation(GO:0046642) regulation of CD4-positive, alpha-beta T cell activation(GO:2000514) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 10.8 GO:0030891 VCB complex(GO:0030891)
0.7 2.2 GO:0098753 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.6 4.8 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.6 13.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 2.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.3 1.1 GO:0043291 RAVE complex(GO:0043291)
0.3 1.5 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.2 6.7 GO:0031594 neuromuscular junction(GO:0031594)
0.2 8.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.2 3.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 0.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 1.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 2.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 2.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 0.5 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.6 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 2.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.4 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.5 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 8.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 10.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.6 GO:0035861 site of double-strand break(GO:0035861)
0.1 4.7 GO:0016342 catenin complex(GO:0016342)
0.1 1.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 3.4 GO:0008305 integrin complex(GO:0008305)
0.1 1.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.5 GO:0030897 HOPS complex(GO:0030897)
0.1 1.6 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.0 4.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.2 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 1.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 1.9 GO:0030141 secretory granule(GO:0030141)
0.0 2.6 GO:0005604 basement membrane(GO:0005604)
0.0 2.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 7.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 4.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 30.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.7 8.5 GO:0016531 copper chaperone activity(GO:0016531)
1.2 5.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
1.1 10.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.8 3.1 GO:0101006 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.7 12.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.7 5.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.6 2.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.6 1.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 2.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.5 5.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.5 4.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.5 1.9 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.4 3.0 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.4 2.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.4 2.0 GO:2001070 starch binding(GO:2001070)
0.4 2.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3 2.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.3 2.2 GO:0070888 E-box binding(GO:0070888)
0.3 16.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 8.2 GO:0008483 transaminase activity(GO:0008483)
0.3 8.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 1.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.3 1.9 GO:0031705 bombesin receptor binding(GO:0031705)
0.2 3.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 3.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 1.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 10.0 GO:0015485 cholesterol binding(GO:0015485)
0.2 2.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 2.6 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 4.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 2.4 GO:2001069 glycogen binding(GO:2001069)
0.2 1.8 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.2 4.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 0.5 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 3.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 1.3 GO:0004067 asparaginase activity(GO:0004067)
0.2 1.5 GO:0016918 retinal binding(GO:0016918)
0.2 2.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.8 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.8 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 1.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 2.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 1.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 9.4 GO:0008201 heparin binding(GO:0008201)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 1.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 2.1 GO:0016208 AMP binding(GO:0016208)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 2.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 7.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.1 2.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.3 GO:0032183 SUMO binding(GO:0032183)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 3.0 GO:0005178 integrin binding(GO:0005178)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.8 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 1.6 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 2.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 4.7 GO:0045296 cadherin binding(GO:0045296)
0.0 8.2 GO:0042277 peptide binding(GO:0042277)
0.0 2.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 3.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0031628 opioid receptor binding(GO:0031628)
0.0 3.9 GO:0019955 cytokine binding(GO:0019955)
0.0 0.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.3 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 3.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 3.1 GO:0015293 symporter activity(GO:0015293)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 2.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.7 GO:0019902 phosphatase binding(GO:0019902)
0.0 2.4 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.3 GO:0042805 actinin binding(GO:0042805)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 2.6 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.4 31.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.3 3.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 2.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 2.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 2.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle