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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr4a1

Z-value: 0.89

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Transcription factors associated with nr4a1

Gene Symbol Gene ID Gene Info
nr4a1
ENSDARG00000000796 nuclear receptor subfamily 4, group A, member 1
nr4a1
ENSDARG00000109473 nuclear receptor subfamily 4, group A, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a1dr11_v1_chr23_-_32156278_321562780.571.0e-02Click!

Activity profile of nr4a1 motif

Sorted Z-values of nr4a1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_11385155 5.45 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr5_+_1278092 5.20 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr19_-_703898 3.44 ENSDART00000181096
ENSDART00000121462
slc6a19a.2
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr23_-_45504991 2.98 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr5_+_45677781 2.97 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr1_-_50838160 2.79 ENSDART00000163939
ENSDART00000165111
zgc:154142
zgc:154142
chr15_-_12270857 2.76 ENSDART00000170093
si:dkey-36i7.3
si:dkey-36i7.3
chr25_+_29160102 2.68 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr8_-_14052349 2.10 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr20_-_14206698 1.98 ENSDART00000082441
dlgap2b
discs, large (Drosophila) homolog-associated protein 2b
chr6_-_31348999 1.97 ENSDART00000153734
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr10_-_17745345 1.95 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
si:dkey-200l5.4
chr3_+_30257582 1.90 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
mybpc2a
myosin binding protein C, fast type a
chr5_-_24238733 1.82 ENSDART00000138170
plscr3a
phospholipid scramblase 3a
chr6_-_10320676 1.77 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr1_+_44826593 1.74 ENSDART00000162200
STX3
zgc:165520
chr6_-_53204808 1.72 ENSDART00000160955
slc38a3b
solute carrier family 38, member 3b
chr1_+_19332837 1.68 ENSDART00000078594
tyrp1b
tyrosinase-related protein 1b
chr21_+_10076203 1.65 ENSDART00000190383
CABZ01043506.1

chr7_-_39552314 1.63 ENSDART00000134174
slc22a18
solute carrier family 22, member 18
chr22_-_16997475 1.62 ENSDART00000090237
nfia
nuclear factor I/A
chr6_-_49873020 1.59 ENSDART00000148511
gnas
GNAS complex locus
chr18_-_15771551 1.59 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
si:ch211-219a15.3
chr7_+_34620418 1.58 ENSDART00000081338
slc9a5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr7_-_42206720 1.52 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr7_-_39551913 1.44 ENSDART00000173498
ENSDART00000143040
slc22a18
solute carrier family 22, member 18
chr14_+_14225048 1.44 ENSDART00000168749
nlgn3a
neuroligin 3a
chr2_-_11912347 1.43 ENSDART00000023851
abhd3
abhydrolase domain containing 3
chr13_-_21739142 1.40 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr5_+_19448078 1.39 ENSDART00000088968
ube3b
ubiquitin protein ligase E3B
chr14_+_14224730 1.35 ENSDART00000180112
ENSDART00000184891
ENSDART00000174760
nlgn3a
neuroligin 3a
chr5_-_36549024 1.35 ENSDART00000097671
zgc:158432
zgc:158432
chr6_+_3282809 1.29 ENSDART00000187444
ENSDART00000187407
ENSDART00000191883
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr10_+_41668483 1.21 ENSDART00000127073
lrrc75bb
leucine rich repeat containing 75Bb
chr11_-_17713987 1.21 ENSDART00000090401
fam19a4b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr11_+_1409622 1.20 ENSDART00000157042
ppp1r3db
protein phosphatase 1, regulatory subunit 3Db
chr23_+_21544227 1.17 ENSDART00000140253
arhgef10lb
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr10_-_25699454 1.11 ENSDART00000064376
sod1
superoxide dismutase 1, soluble
chr8_+_26125218 1.10 ENSDART00000145095
celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr21_-_30648106 1.10 ENSDART00000160800
ENSDART00000177022
phka1b
phosphorylase kinase, alpha 1b (muscle)
chr21_-_43527198 1.08 ENSDART00000126092
irs4a
insulin receptor substrate 4a
chr3_-_37351225 1.07 ENSDART00000174685
si:ch211-278a6.1
si:ch211-278a6.1
chr10_+_7563755 1.05 ENSDART00000165877
purg
purine-rich element binding protein G
chr12_-_31457301 1.04 ENSDART00000043887
ENSDART00000148603
acsl5
acyl-CoA synthetase long chain family member 5
chr8_-_45835056 1.04 ENSDART00000022242
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr5_+_62611400 1.04 ENSDART00000132054
abr
active BCR-related
chr12_-_6880694 1.04 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr8_+_10404310 1.03 ENSDART00000185573
tbc1d22b
TBC1 domain family, member 22B
chr7_+_44484853 1.01 ENSDART00000189079
ENSDART00000121826
bean1
brain expressed, associated with NEDD4, 1
chr7_+_42206847 1.01 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr7_-_24005268 1.00 ENSDART00000173608
si:dkey-183c6.9
si:dkey-183c6.9
chr19_+_3056450 0.96 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr17_-_7371564 0.95 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr18_-_2433011 0.93 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr16_+_19677484 0.93 ENSDART00000150588
tmem196b
transmembrane protein 196b
chr1_-_23110740 0.92 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr7_+_17229282 0.91 ENSDART00000097982
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr15_+_28268135 0.90 ENSDART00000152536
ENSDART00000188550
myo1cb
myosin Ic, paralog b
chr20_+_46897504 0.89 ENSDART00000158124
si:ch73-21k16.1
si:ch73-21k16.1
chr3_-_5829501 0.88 ENSDART00000091017
pkn1b
protein kinase N1b
chr18_+_27515640 0.88 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr6_-_35738836 0.86 ENSDART00000111642
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr25_-_31898552 0.86 ENSDART00000156128
si:ch73-330k17.3
si:ch73-330k17.3
chr7_+_56253914 0.84 ENSDART00000073594
ankrd11
ankyrin repeat domain 11
chr22_+_21317597 0.83 ENSDART00000132605
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr11_+_11201096 0.82 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr12_+_24562667 0.81 ENSDART00000056256
nrxn1a
neurexin 1a
chr14_+_36628131 0.81 ENSDART00000188625
ENSDART00000125345
TENM3
si:dkey-237h12.3
chr20_+_40150612 0.81 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
trdn
triadin
chr21_+_23953181 0.79 ENSDART00000145541
ENSDART00000065599
ENSDART00000112869
cadm1a
cell adhesion molecule 1a
chr23_+_3538463 0.77 ENSDART00000172758
si:dkey-9l20.3
si:dkey-9l20.3
chr16_-_22294265 0.77 ENSDART00000124718
aqp10a
aquaporin 10a
chr9_-_30346279 0.76 ENSDART00000089488
sytl5
synaptotagmin-like 5
chr7_-_24046999 0.76 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr18_+_50461981 0.75 ENSDART00000158761
CU896640.1

chr7_+_34297271 0.74 ENSDART00000180342
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr10_+_7564106 0.71 ENSDART00000159042
purg
purine-rich element binding protein G
chr18_+_31410652 0.70 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr2_+_10127762 0.70 ENSDART00000100726
insl5b
insulin-like 5b
chr11_-_44999858 0.70 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr5_+_65493699 0.68 ENSDART00000161567
si:dkey-21e5.1
si:dkey-21e5.1
chr16_-_16619854 0.65 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cyp21a2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr3_-_30388525 0.64 ENSDART00000183790
lrrc4ba
leucine rich repeat containing 4Ba
chr18_-_42333428 0.64 ENSDART00000034225
cntn5
contactin 5
chr17_+_5800286 0.63 ENSDART00000175504
rp1l1a
retinitis pigmentosa 1-like 1a
chr12_+_46708920 0.61 ENSDART00000153089
exoc7
exocyst complex component 7
chr12_+_21525496 0.61 ENSDART00000152974
ca10a
carbonic anhydrase Xa
chr25_+_6266009 0.60 ENSDART00000148995
slc25a44a
solute carrier family 25, member 44 a
chr4_-_7212875 0.59 ENSDART00000161297
lrrn3b
leucine rich repeat neuronal 3b
chr8_+_10823069 0.59 ENSDART00000081341
mapk13
mitogen-activated protein kinase 13
chr12_+_9817440 0.58 ENSDART00000137081
ENSDART00000123712
rundc3ab
RUN domain containing 3Ab
chr6_-_39764995 0.57 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr21_+_7900107 0.56 ENSDART00000056560
ch25hl2
cholesterol 25-hydroxylase like 2
chr20_-_26060154 0.56 ENSDART00000151950
serac1
serine active site containing 1
chr8_-_15991473 0.55 ENSDART00000151746
agbl4
ATP/GTP binding protein-like 4
chr8_-_15991801 0.55 ENSDART00000132005
agbl4
ATP/GTP binding protein-like 4
chr7_-_31794476 0.55 ENSDART00000142385
nap1l4b
nucleosome assembly protein 1-like 4b
chr5_-_66301142 0.55 ENSDART00000067541
prlrb
prolactin receptor b
chr20_-_27711970 0.55 ENSDART00000139637
zbtb25
zinc finger and BTB domain containing 25
chr15_+_29292154 0.55 ENSDART00000137817
rap1gap2a
RAP1 GTPase activating protein 2a
chr13_+_43050562 0.54 ENSDART00000016602
cdh23
cadherin-related 23
chr8_+_25629941 0.54 ENSDART00000186925
wasa
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a
chr25_+_16214854 0.53 ENSDART00000109672
ENSDART00000190093
mical2b
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr17_-_47305034 0.53 ENSDART00000150116
alk
ALK receptor tyrosine kinase
chr6_+_40952031 0.53 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr3_+_32553714 0.52 ENSDART00000165638
pax10
paired box 10
chr7_+_65398161 0.51 ENSDART00000166109
ENSDART00000157399
usp47
ubiquitin specific peptidase 47
chr6_-_24392426 0.50 ENSDART00000163965
brdt
bromodomain, testis-specific
chr18_+_27926839 0.49 ENSDART00000191835
hipk3b
homeodomain interacting protein kinase 3b
chr8_-_23578660 0.49 ENSDART00000039080
wasb
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr1_+_44826367 0.49 ENSDART00000146962
STX3
zgc:165520
chr19_+_34169055 0.48 ENSDART00000135592
ENSDART00000186043
poc1bl
POC1 centriolar protein homolog B (Chlamydomonas), like
chr17_+_450956 0.48 ENSDART00000183022
ENSDART00000171386
zgc:194887
zgc:194887
chr22_-_11833317 0.48 ENSDART00000125423
ENSDART00000000192
ptpn4b
protein tyrosine phosphatase, non-receptor type 4b
chr8_+_51084993 0.48 ENSDART00000127709
ENSDART00000053768
DISP3
si:dkey-32e23.6
chr15_+_40281693 0.48 ENSDART00000186565
gal3st2
galactose-3-O-sulfotransferase 2
chr25_+_22017182 0.48 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr19_+_2275019 0.47 ENSDART00000136138
itgb8
integrin, beta 8
chr22_-_16997246 0.47 ENSDART00000090242
nfia
nuclear factor I/A
chr24_-_24848612 0.45 ENSDART00000190941
crhb
corticotropin releasing hormone b
chr16_-_50203058 0.45 ENSDART00000154570
vsig10l
V-set and immunoglobulin domain containing 10 like
chr8_+_53120278 0.45 ENSDART00000125232
nr2c2
nuclear receptor subfamily 2, group C, member 2
chr2_-_4787566 0.44 ENSDART00000160663
ENSDART00000157808
tnk2b
tyrosine kinase, non-receptor, 2b
chr7_+_34296789 0.43 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr8_-_45834825 0.42 ENSDART00000132965
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr5_-_50600512 0.42 ENSDART00000190318
mctp1a
multiple C2 domains, transmembrane 1a
chr2_-_44971551 0.41 ENSDART00000018818
mul1a
mitochondrial E3 ubiquitin protein ligase 1a
chr6_+_41957280 0.41 ENSDART00000050114
oxtr
oxytocin receptor
chr5_+_24282570 0.40 ENSDART00000041905
zdhhc23a
zinc finger, DHHC-type containing 23a
chr6_+_515181 0.38 ENSDART00000171374
CACNA1I (1 of many)
si:ch73-379f7.5
chr13_+_22479988 0.38 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr4_-_19921410 0.38 ENSDART00000184359
ENSDART00000179965
BX323820.1

chr12_-_48127985 0.38 ENSDART00000193805
npffr1
neuropeptide FF receptor 1
chr12_-_36268723 0.37 ENSDART00000113740
kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr4_-_2975461 0.37 ENSDART00000150794
plekha5
pleckstrin homology domain containing, family A member 5
chr18_+_44769027 0.37 ENSDART00000145190
ilvbl
ilvB (bacterial acetolactate synthase)-like
chr5_+_10046643 0.36 ENSDART00000137543
ENSDART00000186917
gstt2
glutathione S-transferase theta 2
chr3_-_41292275 0.35 ENSDART00000144088
sdk1a
sidekick cell adhesion molecule 1a
chr24_+_2961098 0.35 ENSDART00000163760
ENSDART00000170835
eci2
enoyl-CoA delta isomerase 2
chr2_+_43755274 0.34 ENSDART00000138620
arhgap12a
Rho GTPase activating protein 12a
chr3_-_54500354 0.33 ENSDART00000124215
trip10a
thyroid hormone receptor interactor 10a
chr11_-_15090118 0.32 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr15_+_1705167 0.31 ENSDART00000081940
otol1b
otolin 1b
chr2_+_34767171 0.30 ENSDART00000145451
astn1
astrotactin 1
chr17_+_30546579 0.30 ENSDART00000154385
nhsl1a
NHS-like 1a
chr16_-_45288599 0.30 ENSDART00000044097
hpn
hepsin
chr5_-_23200880 0.30 ENSDART00000051531
iqcd
IQ motif containing D
chr18_-_4957022 0.29 ENSDART00000101686
zbbx
zinc finger, B-box domain containing
chr3_-_22212764 0.29 ENSDART00000155490
maptb
microtubule-associated protein tau b
chr1_-_40208237 0.29 ENSDART00000191987
AL953865.1

chr20_-_31743553 0.28 ENSDART00000087405
sash1a
SAM and SH3 domain containing 1a
chr14_-_17121676 0.27 ENSDART00000170154
ENSDART00000060479
smtnl1
smoothelin-like 1
chr6_-_8498908 0.27 ENSDART00000149222
pglyrp2
peptidoglycan recognition protein 2
chr11_+_5681762 0.26 ENSDART00000179139
arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr15_-_16946124 0.25 ENSDART00000154923
hip1
huntingtin interacting protein 1
chr13_+_22480496 0.25 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr15_-_21239416 0.24 ENSDART00000155787
A2ML1 (1 of many)
si:dkey-105h12.2
chr8_-_979735 0.21 ENSDART00000149612
znf366
zinc finger protein 366
chr3_-_51109286 0.20 ENSDART00000172010
si:ch211-148f13.1
si:ch211-148f13.1
chr11_-_31226578 0.20 ENSDART00000109698
nacc1b
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr6_-_39765546 0.20 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr21_-_22724980 0.19 ENSDART00000035469
c1qa
complement component 1, q subcomponent, A chain
chr20_-_26937453 0.18 ENSDART00000139756
ftr97
finTRIM family, member 97
chr7_-_31794878 0.17 ENSDART00000099748
nap1l4b
nucleosome assembly protein 1-like 4b
chr6_-_45995401 0.16 ENSDART00000154392
ca16b
carbonic anhydrase XVI b
chr7_-_44909540 0.15 ENSDART00000193378
ENSDART00000109534
cdh16
cadherin 16, KSP-cadherin
chr8_+_21406769 0.14 ENSDART00000135766
si:dkey-163f12.6
si:dkey-163f12.6
chr3_+_32842825 0.13 ENSDART00000122228
prr14
proline rich 14
chr23_+_26003187 0.12 ENSDART00000147271
wisp2
WNT1 inducible signaling pathway protein 2
chr5_+_38462121 0.11 ENSDART00000144425
gltpd2
glycolipid transfer protein domain containing 2
chr9_-_9419704 0.11 ENSDART00000138996
si:ch211-214p13.9
si:ch211-214p13.9
chr20_-_26936887 0.10 ENSDART00000160827
ftr79
finTRIM family, member 79
chr17_+_30545895 0.09 ENSDART00000076739
nhsl1a
NHS-like 1a
chr20_-_48701593 0.09 ENSDART00000132835
pax1b
paired box 1b
chr22_+_24673168 0.05 ENSDART00000135257
si:rp71-23d18.8
si:rp71-23d18.8
chr14_-_32258759 0.05 ENSDART00000052949
fgf13a
fibroblast growth factor 13a
chr18_+_9382847 0.05 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr20_-_25369767 0.03 ENSDART00000180278
itsn2a
intersectin 2a
chr5_+_19413838 0.02 ENSDART00000089014
ENSDART00000146215
myo1ha
myosin IHa
chr13_-_42673978 0.01 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
lrrfip2
leucine rich repeat (in FLII) interacting protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.5 3.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.4 1.7 GO:0006867 asparagine transport(GO:0006867)
0.4 2.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 1.0 GO:1903961 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.3 1.7 GO:0097066 response to thyroid hormone(GO:0097066)
0.3 1.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.3 1.4 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.3 4.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 2.8 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.2 0.5 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.2 1.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.1 1.6 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.4 GO:0007567 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.1 2.0 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.9 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.1 1.1 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.5 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 3.0 GO:0051180 vitamin transport(GO:0051180)
0.1 0.3 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.4 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 1.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.0 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 1.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 1.2 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.8 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.0 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 4.7 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.1 1.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.9 GO:0032438 melanosome organization(GO:0032438)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 2.1 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 1.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.0 GO:0009408 response to heat(GO:0009408)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.0 1.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.4 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 3.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.9 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.9 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 4.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.5 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.6 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.5 GO:0031647 regulation of protein stability(GO:0031647)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.3 4.9 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 2.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.4 GO:0005948 acetolactate synthase complex(GO:0005948)
0.1 0.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.6 GO:0032420 stereocilium(GO:0032420)
0.1 1.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 2.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 3.0 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.6 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0005499 vitamin D binding(GO:0005499)
0.5 1.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 2.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 1.6 GO:0051430 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 1.7 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.3 1.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.8 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.2 1.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 1.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.6 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.4 GO:0004990 oxytocin receptor activity(GO:0004990)
0.1 0.4 GO:0003984 acetolactate synthase activity(GO:0003984)
0.1 3.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.5 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 0.6 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 1.2 GO:2001069 glycogen binding(GO:2001069)
0.1 1.8 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 2.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 3.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.0 GO:0030276 clathrin binding(GO:0030276)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 3.3 GO:0015293 symporter activity(GO:0015293)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 2.0 GO:0060090 binding, bridging(GO:0060090)
0.0 4.7 GO:0008017 microtubule binding(GO:0008017)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 2.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors