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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr4a2a

Z-value: 1.45

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Transcription factors associated with nr4a2a

Gene Symbol Gene ID Gene Info
nr4a2a
ENSDARG00000017007 nuclear receptor subfamily 4, group A, member 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a2adr11_v1_chr9_-_5045378_5045378-0.551.4e-02Click!

Activity profile of nr4a2a motif

Sorted Z-values of nr4a2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_16451375 6.26 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr20_-_29499363 5.63 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr10_+_22775253 4.98 ENSDART00000190141
tmem88a
transmembrane protein 88 a
chr19_-_47571456 4.76 ENSDART00000158071
ENSDART00000165841
rrm2
ribonucleotide reductase M2 polypeptide
chr23_-_21471022 4.47 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr2_-_34138400 4.44 ENSDART00000056667
cenpl
centromere protein L
chr17_+_17764979 4.38 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr5_-_14509137 4.21 ENSDART00000180742
si:ch211-244o22.2
si:ch211-244o22.2
chr13_+_33651416 3.61 ENSDART00000180221
BX005372.1

chr17_-_51224159 3.24 ENSDART00000185749
psen1
presenilin 1
chr13_-_37127970 3.11 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr22_+_20141528 3.10 ENSDART00000187770
eef2a.1
eukaryotic translation elongation factor 2a, tandem duplicate 1
chr20_+_36806398 2.97 ENSDART00000153317
abracl
ABRA C-terminal like
chr18_+_38288877 2.92 ENSDART00000134247
lmo2
LIM domain only 2 (rhombotin-like 1)
chr22_-_7050 2.84 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr3_-_18575868 2.77 ENSDART00000122968
aqp8b
aquaporin 8b
chr1_-_39859626 2.63 ENSDART00000053763
dctd
dCMP deaminase
chr12_+_27024676 2.55 ENSDART00000153104
msl1b
male-specific lethal 1 homolog b (Drosophila)
chr1_-_17650223 2.51 ENSDART00000043484
si:dkey-256e7.5
si:dkey-256e7.5
chr24_-_1021318 2.48 ENSDART00000181403
ralaa
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr1_+_39859782 2.46 ENSDART00000149984
irf2a
interferon regulatory factor 2a
chr14_+_32852388 2.41 ENSDART00000166351
nkrf
NFKB repressing factor
chr11_+_31380495 2.37 ENSDART00000185073
sipa1l2
signal-induced proliferation-associated 1 like 2
chr16_-_25680666 2.37 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr6_+_7250824 2.28 ENSDART00000177226
dzip1
DAZ interacting zinc finger protein 1
chr21_-_25250594 2.21 ENSDART00000163862
nfrkb
nuclear factor related to kappaB binding protein
chr1_-_33556428 2.15 ENSDART00000187346
creb1a
cAMP responsive element binding protein 1a
chr12_-_26415499 2.12 ENSDART00000185779
synpo2lb
synaptopodin 2-like b
chr8_+_15251448 2.07 ENSDART00000063717
zgc:171480
zgc:171480
chr23_+_5524247 2.07 ENSDART00000189679
ENSDART00000083622
tead3a
TEA domain family member 3 a
chr1_+_24557414 2.06 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr3_-_13599482 2.06 ENSDART00000166639
tufm
Tu translation elongation factor, mitochondrial
chr17_+_48314724 2.03 ENSDART00000125617
smoc1
SPARC related modular calcium binding 1
chr7_-_33684632 2.03 ENSDART00000130553
tle3b
transducin-like enhancer of split 3b
chr5_+_36896933 1.96 ENSDART00000151984
srsf7a
serine/arginine-rich splicing factor 7a
chr22_-_15593824 1.95 ENSDART00000123125
tpm4a
tropomyosin 4a
chr14_+_7898372 1.93 ENSDART00000159593
ube2d2
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr21_+_19330774 1.88 ENSDART00000109412
helq
helicase, POLQ like
chr5_-_10082244 1.87 ENSDART00000036421
chek2
checkpoint kinase 2
chr15_+_19324697 1.84 ENSDART00000022015
vps26b
VPS26 retromer complex component B
chr6_-_11523987 1.84 ENSDART00000189363
gulp1b
GULP, engulfment adaptor PTB domain containing 1b
chr16_-_39131666 1.83 ENSDART00000075517
gdf6a
growth differentiation factor 6a
chr17_-_15189397 1.81 ENSDART00000133710
ENSDART00000110507
wdhd1
WD repeat and HMG-box DNA binding protein 1
chr15_+_24644016 1.80 ENSDART00000043292
smtnl
smoothelin, like
chr11_-_39118882 1.79 ENSDART00000113185
ENSDART00000156526
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr11_-_41966854 1.78 ENSDART00000055709
her2
hairy-related 2
chr18_-_48508585 1.76 ENSDART00000133364
kcnj1a.4
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 4
chr20_+_7243879 1.76 ENSDART00000122298
bsnd
barttin CLCNK-type chloride channel accessory beta subunit
chr17_+_5976683 1.74 ENSDART00000110276
zgc:194275
zgc:194275
chr3_+_36646054 1.73 ENSDART00000170013
ENSDART00000159948
gspt1l
G1 to S phase transition 1, like
chr22_+_29113796 1.68 ENSDART00000150264
pla2g6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr9_+_32872690 1.68 ENSDART00000020798
si:dkey-145p14.5
si:dkey-145p14.5
chr23_-_24488696 1.67 ENSDART00000155593
tmem82
transmembrane protein 82
chr8_+_16758304 1.67 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr2_+_37836821 1.67 ENSDART00000143203
parp2
poly (ADP-ribose) polymerase 2
chr22_-_37834312 1.65 ENSDART00000076128
ppp1r2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr15_+_24644251 1.64 ENSDART00000181660
smtnl
smoothelin, like
chr21_-_22317920 1.63 ENSDART00000191083
ENSDART00000108701
gdpd4b
glycerophosphodiester phosphodiesterase domain containing 4b
chr3_-_14695033 1.59 ENSDART00000133850
gadd45gip1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr2_-_56649883 1.58 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr10_+_10788811 1.57 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr24_-_28419444 1.56 ENSDART00000105749
nrros
negative regulator of reactive oxygen species
chr24_-_6024466 1.55 ENSDART00000040865
pdss1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr13_+_2523032 1.54 ENSDART00000172261
lhb
luteinizing hormone, beta polypeptide
chr20_+_49081967 1.54 ENSDART00000112689
crnkl1
crooked neck pre-mRNA splicing factor 1
chr15_-_37875601 1.52 ENSDART00000122439
si:dkey-238d18.4
si:dkey-238d18.4
chr13_+_31497236 1.51 ENSDART00000146752
lrrc9
leucine rich repeat containing 9
chr7_-_33351485 1.50 ENSDART00000146420
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr21_+_5080789 1.49 ENSDART00000024199
atp5fa1
ATP synthase F1 subunit alpha
chr23_-_9855627 1.49 ENSDART00000180159
prkcbp1l
protein kinase C binding protein 1, like
chr15_+_11840311 1.49 ENSDART00000167671
prkd2
protein kinase D2
chr4_+_9536860 1.49 ENSDART00000130083
lsm8
LSM8 homolog, U6 small nuclear RNA associated
chr7_+_46020508 1.47 ENSDART00000170294
ccne1
cyclin E1
chr3_-_49925313 1.47 ENSDART00000164361
gcgra
glucagon receptor a
chr23_+_2714949 1.46 ENSDART00000105284
ncoa6
nuclear receptor coactivator 6
chr7_+_66634167 1.43 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr1_-_52494122 1.43 ENSDART00000131407
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr18_-_48517040 1.43 ENSDART00000143645
kcnj1a.3
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 3
chr24_-_21934571 1.42 ENSDART00000113092
tagln3b
transgelin 3b
chr6_+_7533601 1.41 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr4_+_25410293 1.39 ENSDART00000046253
ENSDART00000123680
prkcq
protein kinase C, theta
chr13_+_31321297 1.39 ENSDART00000143308
antxr1d
anthrax toxin receptor 1d
chr8_+_25893071 1.38 ENSDART00000078161
tmem115
transmembrane protein 115
chr5_-_17601759 1.38 ENSDART00000138387
si:ch211-130h14.6
si:ch211-130h14.6
chr5_+_37729207 1.38 ENSDART00000184378
cdc42ep2
CDC42 effector protein (Rho GTPase binding) 2
chr3_-_40254634 1.36 ENSDART00000154562
top3a
DNA topoisomerase III alpha
chr10_-_41285235 1.36 ENSDART00000141190
brf2
BRF2, RNA polymerase III transcription initiation factor
chr6_-_9922266 1.35 ENSDART00000151549
pimr73
Pim proto-oncogene, serine/threonine kinase, related 73
chr2_+_2168547 1.34 ENSDART00000029347
higd1a
HIG1 hypoxia inducible domain family, member 1A
chr18_-_24988645 1.34 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr5_+_20693724 1.34 ENSDART00000141368
si:ch211-240b21.2
si:ch211-240b21.2
chr17_-_53353653 1.32 ENSDART00000180744
ENSDART00000026879
unm_sa911
un-named sa911
chr7_-_33683891 1.31 ENSDART00000175980
ENSDART00000191148
ENSDART00000173569
tle3b
transducin-like enhancer of split 3b
chr8_-_22542467 1.30 ENSDART00000182588
ENSDART00000134542
csde1
cold shock domain containing E1, RNA-binding
chr9_+_29548195 1.30 ENSDART00000176057
rnf17
ring finger protein 17
chr8_-_17184482 1.29 ENSDART00000025803
pola2
polymerase (DNA directed), alpha 2
chr16_-_41787421 1.29 ENSDART00000147210
si:dkey-199f5.8
si:dkey-199f5.8
chr25_-_16755340 1.28 ENSDART00000124729
ENSDART00000110859
ribc2
RIB43A domain with coiled-coils 2
chr13_-_11035420 1.25 ENSDART00000108709
cep170aa
centrosomal protein 170Aa
chr20_+_37825804 1.24 ENSDART00000152865
tatdn3
TatD DNase domain containing 3
chr11_+_11271959 1.24 ENSDART00000190678
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr12_-_29305533 1.24 ENSDART00000189410
sh2d4bb
SH2 domain containing 4Bb
chr17_-_25303486 1.23 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr11_+_7432533 1.22 ENSDART00000180977
adgrl2a
adhesion G protein-coupled receptor L2a
chr7_+_22586800 1.21 ENSDART00000035325
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr25_+_20272145 1.20 ENSDART00000109605
si:dkey-219c3.2
si:dkey-219c3.2
chr12_-_34827477 1.20 ENSDART00000153026
NDUFAF8
si:dkey-21c1.6
chr24_+_24014880 1.19 ENSDART00000041335
chodl
chondrolectin
chr13_+_2394264 1.19 ENSDART00000168595
elovl5
ELOVL fatty acid elongase 5
chr3_+_31680592 1.18 ENSDART00000172456
mylk5
myosin, light chain kinase 5
chr22_-_14247276 1.18 ENSDART00000033332
si:ch211-246m6.5
si:ch211-246m6.5
chr7_+_39679944 1.18 ENSDART00000133420
tbc1d14
TBC1 domain family, member 14
chr22_+_11153590 1.18 ENSDART00000188207
bcor
BCL6 corepressor
chr6_+_32393057 1.16 ENSDART00000190765
dock7
dedicator of cytokinesis 7
chr7_-_26601307 1.16 ENSDART00000188934
plscr3b
phospholipid scramblase 3b
chr5_+_63288599 1.15 ENSDART00000140065
si:ch73-37h15.2
si:ch73-37h15.2
chr22_-_14262115 1.15 ENSDART00000168264
si:ch211-246m6.5
si:ch211-246m6.5
chr11_-_30634286 1.15 ENSDART00000191019
zgc:153665
zgc:153665
chr6_+_50381347 1.14 ENSDART00000055504
cyc1
cytochrome c-1
chr19_+_28187480 1.14 ENSDART00000183825
irx4b
iroquois homeobox 4b
chr5_+_22677786 1.12 ENSDART00000142112
vma21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr9_+_38644976 1.12 ENSDART00000133849
ENSDART00000135774
slc12a8
solute carrier family 12, member 8
chr2_-_10564019 1.11 ENSDART00000132167
ccdc18
coiled-coil domain containing 18
chr4_-_965267 1.11 ENSDART00000093289
atp23
ATP23 metallopeptidase and ATP synthase assembly factor homolog
chr19_+_11214007 1.08 ENSDART00000127362
si:ch73-109i22.2
si:ch73-109i22.2
chr2_+_2967255 1.07 ENSDART00000167649
ENSDART00000166449
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr22_-_24285432 1.07 ENSDART00000164083
si:ch211-117l17.4
si:ch211-117l17.4
chr5_-_43819663 1.07 ENSDART00000022481
mccc2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr21_+_22330005 1.05 ENSDART00000140751
ENSDART00000157839
ENSDART00000140468
nadk2
NAD kinase 2, mitochondrial
chr1_-_28861226 1.05 ENSDART00000075502
timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr16_+_53278406 1.05 ENSDART00000010792
ptdss1a
phosphatidylserine synthase 1a
chr9_-_33477588 1.04 ENSDART00000144150
caska
calcium/calmodulin-dependent serine protein kinase a
chr10_-_20105553 1.04 ENSDART00000184502
pbdc1
polysaccharide biosynthesis domain containing 1
chr17_+_53424415 1.04 ENSDART00000157022
slc9a1b
solute carrier family 9 member A1b
chr3_+_50201240 1.04 ENSDART00000156347
epn3a
epsin 3a
chr8_-_26033176 1.03 ENSDART00000184533
BX784025.1

chr14_-_48103207 1.02 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr18_+_5273953 1.02 ENSDART00000165073
slc12a1
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr6_+_52924103 1.01 ENSDART00000065693
or137-2
odorant receptor, family H, subfamily 137, member 2
chr18_-_48492951 1.01 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr17_-_43287290 1.00 ENSDART00000156885
EML5
si:dkey-1f12.3
chr10_-_5024520 0.99 ENSDART00000020631
ENSDART00000189017
hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like
chr6_-_13206255 0.98 ENSDART00000065373
eef1b2
eukaryotic translation elongation factor 1 beta 2
chr15_-_33834577 0.98 ENSDART00000163354
mmp13b
matrix metallopeptidase 13b
chr5_+_4564233 0.98 ENSDART00000193435
CABZ01058647.1

chr23_+_19701587 0.96 ENSDART00000104425
dnase1l1
deoxyribonuclease I-like 1
chr19_-_9712530 0.96 ENSDART00000134816
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr10_+_22918338 0.93 ENSDART00000167874
ENSDART00000171298
zgc:103508
zgc:103508
chr19_+_13410903 0.93 ENSDART00000165033
ENSDART00000168672
srsf4
serine/arginine-rich splicing factor 4
chr13_+_7241170 0.92 ENSDART00000109434
aifm2
apoptosis-inducing factor, mitochondrion-associated, 2
chr14_+_35428152 0.92 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr22_-_3182965 0.90 ENSDART00000158009
lonp1
lon peptidase 1, mitochondrial
chr3_+_46764022 0.90 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr1_-_58868306 0.89 ENSDART00000166615
dnm2b
dynamin 2b
chr23_+_26142807 0.88 ENSDART00000158878
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr9_+_54644626 0.88 ENSDART00000190609
egfl6
EGF-like-domain, multiple 6
chr16_-_560574 0.87 ENSDART00000148452
irx2a
iroquois homeobox 2a
chr12_+_26670778 0.87 ENSDART00000144355
arhgap12b
Rho GTPase activating protein 12b
chr24_-_30263301 0.86 ENSDART00000162328
snx7
sorting nexin 7
chr3_+_3454610 0.85 ENSDART00000024900
zgc:165453
zgc:165453
chr5_-_3839285 0.83 ENSDART00000122292
mlxipl
MLX interacting protein like
chr8_+_48484455 0.81 ENSDART00000122737
PRDM16
si:ch211-263k4.2
chr25_-_20378721 0.80 ENSDART00000181707
kctd15a
potassium channel tetramerization domain containing 15a
chr5_+_62723233 0.79 ENSDART00000183718
nanos2
nanos homolog 2
chr19_+_19756425 0.78 ENSDART00000167606
hoxa3a
homeobox A3a
chr25_-_29080063 0.78 ENSDART00000181911
ENSDART00000138087
cox5aa
cytochrome c oxidase subunit Vaa
chr1_-_21287724 0.78 ENSDART00000193900
npy1r
neuropeptide Y receptor Y1
chr18_-_2222128 0.77 ENSDART00000171402
pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr25_-_24240797 0.77 ENSDART00000132790
spty2d1
SPT2 chromatin protein domain containing 1
chr12_+_28799988 0.77 ENSDART00000022724
pnpo
pyridoxamine 5'-phosphate oxidase
chr7_-_51793333 0.77 ENSDART00000180654
BX957362.5

chr2_+_7106837 0.75 ENSDART00000138691
vcam1a
vascular cell adhesion molecule 1a
chr12_+_25223843 0.75 ENSDART00000077180
ENSDART00000127454
ENSDART00000122665
mta3
metastasis associated 1 family, member 3
chr5_+_23201370 0.75 ENSDART00000138123
tpcn1
two pore segment channel 1
chr25_+_3306620 0.75 ENSDART00000182085
ENSDART00000034704
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr19_+_1465004 0.74 ENSDART00000159157
CABZ01073736.1

chr23_+_44157682 0.73 ENSDART00000164474
ENSDART00000149928
si:ch73-106g13.1
si:ch73-106g13.1
chr16_-_45327616 0.73 ENSDART00000158733
si:dkey-33i11.1
si:dkey-33i11.1
chr21_-_1635268 0.71 ENSDART00000151258
zgc:152948
zgc:152948
chr7_+_29012033 0.70 ENSDART00000173909
ENSDART00000145762
dnaaf1
dynein, axonemal, assembly factor 1
chr8_-_13046089 0.70 ENSDART00000137784
si:dkey-208b23.5
si:dkey-208b23.5
chr21_+_16145980 0.70 ENSDART00000135119
qrfpr4
pyroglutamylated RFamide peptide receptor 4
chr7_-_19638319 0.70 ENSDART00000163686
si:ch211-212k18.4
si:ch211-212k18.4
chr21_-_5879897 0.70 ENSDART00000184034
rpl35
ribosomal protein L35
chr7_-_41338923 0.70 ENSDART00000099138
ncf2
neutrophil cytosolic factor 2
chr7_+_32605705 0.69 ENSDART00000173841
fshb
follicle stimulating hormone, beta polypeptide
chr1_-_48933 0.69 ENSDART00000171162
ildr1a
immunoglobulin-like domain containing receptor 1a
chr3_+_33745014 0.69 ENSDART00000159966
nacc1a
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a
chr7_+_22293894 0.68 ENSDART00000056790
tmem256
transmembrane protein 256
chr11_+_5880562 0.67 ENSDART00000129663
ENSDART00000130768
ENSDART00000160909
dazap1
DAZ associated protein 1
chr6_-_43047774 0.67 ENSDART00000161722
glyctk
glycerate kinase
chr3_+_27770110 0.67 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr2_-_3045861 0.67 ENSDART00000105818
ENSDART00000187575
guk1a
guanylate kinase 1a
chr2_-_22660232 0.67 ENSDART00000174742
thap4
THAP domain containing 4
chr13_+_15354012 0.65 ENSDART00000121453
loxl3b
lysyl oxidase-like 3b
chr5_-_60159116 0.65 ENSDART00000147675
si:dkey-280e8.1
si:dkey-280e8.1
chr2_-_55853943 0.65 ENSDART00000122576
rx2
retinal homeobox gene 2
chr13_-_36134317 0.65 ENSDART00000015664
ENSDART00000188301
ENSDART00000191073
ENSDART00000184192
ENSDART00000139593
pcnx
pecanex homolog (Drosophila)
chr6_+_50381665 0.65 ENSDART00000141128
cyc1
cytochrome c-1
chr10_-_36253958 0.65 ENSDART00000126288
or110-2
odorant receptor, family D, subfamily 110, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 2.1 GO:0009219 pyrimidine deoxyribonucleotide metabolic process(GO:0009219)
1.7 5.0 GO:0060923 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
1.2 13.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.9 4.4 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.8 3.2 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.7 2.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.7 4.7 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.5 1.6 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.5 1.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.4 1.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.4 1.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.4 4.2 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.3 1.7 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 2.2 GO:0030728 ovulation(GO:0030728)
0.3 1.8 GO:0007405 neuroblast proliferation(GO:0007405)
0.3 0.8 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.3 0.8 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.3 2.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 1.5 GO:0089700 endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.2 0.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 1.3 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.2 2.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 0.7 GO:0045730 respiratory burst(GO:0045730)
0.2 0.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 3.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.6 GO:0044068 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.2 1.6 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 1.4 GO:1901998 toxin transport(GO:1901998)
0.2 3.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.2 1.1 GO:0006552 leucine catabolic process(GO:0006552)
0.2 1.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.4 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.2 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.1 2.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.7 GO:2000316 regulation of T-helper 17 type immune response(GO:2000316) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.5 GO:0051817 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) modification of morphology or physiology of other organism involved in symbiotic interaction(GO:0051817) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.1 0.8 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.3 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.5 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 1.0 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.5 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 1.2 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 0.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 1.1 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551) regulation of phospholipid metabolic process(GO:1903725)
0.1 0.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 1.4 GO:0006265 DNA topological change(GO:0006265)
0.1 2.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.6 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.5 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 2.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 1.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 1.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 2.2 GO:0035329 hippo signaling(GO:0035329)
0.1 0.7 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.9 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 4.1 GO:0006414 translational elongation(GO:0006414)
0.1 1.9 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.6 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 1.0 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 0.2 GO:0002637 regulation of immunoglobulin production(GO:0002637) positive regulation of immunoglobulin production(GO:0002639)
0.1 0.9 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.1 2.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.4 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 0.2 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 2.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 3.3 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 1.6 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 1.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0070378 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.5 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 1.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.9 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.0 1.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 1.5 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.7 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 1.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.0 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 3.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.9 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 1.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.5 GO:0030217 T cell differentiation(GO:0030217)
0.0 0.3 GO:0061333 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.3 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.5 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.8 GO:0060037 pharyngeal system development(GO:0060037)
0.0 1.8 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.8 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 1.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.8 GO:0006821 chloride transport(GO:0006821)
0.0 0.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 2.5 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.8 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.7 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.2 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.8 GO:0048477 oogenesis(GO:0048477)
0.0 1.4 GO:0006413 translational initiation(GO:0006413)
0.0 1.5 GO:0006913 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 1.9 GO:0006364 rRNA processing(GO:0006364)
0.0 0.3 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.4 GO:0043491 protein kinase B signaling(GO:0043491)
0.0 1.2 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 2.5 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0043198 dendritic shaft(GO:0043198)
0.4 1.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.3 1.7 GO:0018444 translation release factor complex(GO:0018444)
0.3 2.5 GO:0072487 MSL complex(GO:0072487)
0.3 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 2.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 0.9 GO:0017177 glucosidase II complex(GO:0017177)
0.2 1.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 1.4 GO:0001772 immunological synapse(GO:0001772)
0.2 1.5 GO:0000974 Prp19 complex(GO:0000974)
0.2 1.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.2 1.8 GO:0030904 retromer complex(GO:0030904)
0.2 2.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 0.9 GO:0016589 NURF complex(GO:0016589)
0.1 1.5 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 2.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.9 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.3 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 1.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 2.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 3.5 GO:0005814 centriole(GO:0005814)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 4.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 3.4 GO:0016607 nuclear speck(GO:0016607)
0.0 3.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 8.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.0 GO:0005930 axoneme(GO:0005930)
0.0 2.1 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 2.0 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 5.3 GO:0005730 nucleolus(GO:0005730)
0.0 1.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)
0.0 2.3 GO:0005840 ribosome(GO:0005840)
0.0 0.4 GO:0042641 actomyosin(GO:0042641)
0.0 1.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 10.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.1 4.4 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.6 1.9 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.4 3.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 1.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.4 1.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.3 2.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.3 1.7 GO:0034046 poly(G) binding(GO:0034046)
0.3 1.6 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.3 2.8 GO:0015250 water channel activity(GO:0015250)
0.3 4.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 1.5 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.2 1.7 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 1.4 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.2 0.7 GO:0008887 glycerate kinase activity(GO:0008887)
0.2 3.5 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 2.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 2.2 GO:0002020 protease binding(GO:0002020)
0.2 0.8 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 0.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 6.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 2.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 2.9 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 4.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 1.0 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.5 GO:1903924 estradiol binding(GO:1903924)
0.1 0.7 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 1.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.1 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.1 2.5 GO:0019003 GDP binding(GO:0019003)
0.1 1.6 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 1.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.5 GO:0032977 membrane insertase activity(GO:0032977)
0.1 2.6 GO:0019239 deaminase activity(GO:0019239)
0.1 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.4 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 1.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.2 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 1.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 10.7 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 2.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.8 GO:0015108 chloride transmembrane transporter activity(GO:0015108)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 4.9 GO:0003682 chromatin binding(GO:0003682)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0008201 heparin binding(GO:0008201)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 11.9 PID E2F PATHWAY E2F transcription factor network
0.1 3.2 PID ATM PATHWAY ATM pathway
0.1 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 3.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.3 2.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 1.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 1.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 1.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 4.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 4.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production