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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr4a2b

Z-value: 0.81

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Transcription factors associated with nr4a2b

Gene Symbol Gene ID Gene Info
nr4a2b
ENSDARG00000044532 nuclear receptor subfamily 4, group A, member 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a2bdr11_v1_chr6_+_12462079_124620790.643.0e-03Click!

Activity profile of nr4a2b motif

Sorted Z-values of nr4a2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_11385155 3.88 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr1_+_19332837 3.09 ENSDART00000078594
tyrp1b
tyrosinase-related protein 1b
chr5_+_1278092 3.00 ENSDART00000147972
ENSDART00000159783
dnm1a
dynamin 1a
chr17_-_12389259 2.95 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr6_-_31348999 2.55 ENSDART00000153734
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_-_41831646 2.49 ENSDART00000134326
si:dkey-65b12.6
si:dkey-65b12.6
chr23_+_27068225 2.41 ENSDART00000054238
mipa
major intrinsic protein of lens fiber a
chr20_+_106481 2.29 ENSDART00000148834
si:ch1073-155h21.2
si:ch1073-155h21.2
chr25_-_16969922 2.19 ENSDART00000111158
tigara
tp53-induced glycolysis and apoptosis regulator a
chr8_-_14052349 2.15 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr19_-_703898 2.12 ENSDART00000181096
ENSDART00000121462
slc6a19a.2
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr2_+_6885852 2.04 ENSDART00000016607
rgs5b
regulator of G protein signaling 5b
chr10_-_25699454 2.03 ENSDART00000064376
sod1
superoxide dismutase 1, soluble
chr9_+_31795343 2.02 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr23_-_28141419 2.01 ENSDART00000133039
tac3a
tachykinin 3a
chr6_-_35738836 1.81 ENSDART00000111642
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr3_+_17806213 1.80 ENSDART00000055890
znf385c
zinc finger protein 385C
chr9_+_42066030 1.78 ENSDART00000185311
ENSDART00000015267
pcbp3
poly(rC) binding protein 3
chr10_-_17745345 1.66 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
si:dkey-200l5.4
chr23_-_45504991 1.60 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr5_-_16983336 1.59 ENSDART00000038740
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr4_-_4932619 1.38 ENSDART00000103293
ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr4_+_16795688 1.35 ENSDART00000132337
spx
spexin hormone
chr3_+_30257582 1.34 ENSDART00000159497
ENSDART00000103457
ENSDART00000121883
mybpc2a
myosin binding protein C, fast type a
chr3_+_32553714 1.32 ENSDART00000165638
pax10
paired box 10
chr18_-_15771551 1.24 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
si:ch211-219a15.3
chr5_-_13076779 1.21 ENSDART00000192826
ypel1
yippee-like 1
chr15_+_20403903 1.20 ENSDART00000134182
cox7a1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr7_+_34620418 1.18 ENSDART00000081338
slc9a5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr12_+_46708920 1.17 ENSDART00000153089
exoc7
exocyst complex component 7
chr5_-_5669879 1.17 ENSDART00000191963
CABZ01075628.1

chr20_+_40150612 1.15 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
trdn
triadin
chr3_-_28258462 1.13 ENSDART00000191573
rbfox1
RNA binding fox-1 homolog 1
chr7_-_24046999 1.12 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr16_+_20161805 1.11 ENSDART00000192146
c16h2orf66
chromosome 16 C2orf66 homolog
chr6_-_39764995 1.11 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr1_-_51734524 1.09 ENSDART00000109640
ENSDART00000122628
junba
JunB proto-oncogene, AP-1 transcription factor subunit a
chr5_-_41838354 1.03 ENSDART00000146793
si:dkey-65b12.6
si:dkey-65b12.6
chr13_-_21739142 1.02 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr24_-_24848612 1.00 ENSDART00000190941
crhb
corticotropin releasing hormone b
chr2_-_11912347 0.99 ENSDART00000023851
abhd3
abhydrolase domain containing 3
chr8_-_44004135 0.99 ENSDART00000136269
rimbp2
RIMS binding protein 2
chr23_+_21638258 0.98 ENSDART00000104188
igsf21b
immunoglobin superfamily, member 21b
chr11_+_1409622 0.98 ENSDART00000157042
ppp1r3db
protein phosphatase 1, regulatory subunit 3Db
chr22_+_31821815 0.98 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr1_+_44826593 0.97 ENSDART00000162200
STX3
zgc:165520
chr20_-_1151265 0.90 ENSDART00000012376
gabrr1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr24_+_34089977 0.90 ENSDART00000157466
asb10
ankyrin repeat and SOCS box containing 10
chr11_+_11201096 0.82 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr10_+_41668483 0.78 ENSDART00000127073
lrrc75bb
leucine rich repeat containing 75Bb
chr23_+_21544227 0.77 ENSDART00000140253
arhgef10lb
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr4_-_18434924 0.76 ENSDART00000190271
socs2
suppressor of cytokine signaling 2
chr9_-_44905867 0.74 ENSDART00000138316
ENSDART00000131252
ENSDART00000179383
ENSDART00000159337
zgc:66484
zgc:66484
chr13_-_27660955 0.68 ENSDART00000188651
ENSDART00000134494
rims1a
regulating synaptic membrane exocytosis 1a
chr21_-_22724980 0.68 ENSDART00000035469
c1qa
complement component 1, q subcomponent, A chain
chr6_-_10835849 0.66 ENSDART00000005903
ENSDART00000135065
atp5mc3b
ATP synthase membrane subunit c locus 3b
chr15_+_1705167 0.64 ENSDART00000081940
otol1b
otolin 1b
chr18_+_27515640 0.64 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr7_+_44484853 0.64 ENSDART00000189079
ENSDART00000121826
bean1
brain expressed, associated with NEDD4, 1
chr18_+_31410652 0.64 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr1_-_30689004 0.62 ENSDART00000018827
dachc
dachshund c
chr5_+_36611128 0.60 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr19_+_19652439 0.59 ENSDART00000165934
hibadha
3-hydroxyisobutyrate dehydrogenase a
chr2_+_10127762 0.58 ENSDART00000100726
insl5b
insulin-like 5b
chr6_-_39765546 0.57 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr8_+_53120278 0.56 ENSDART00000125232
nr2c2
nuclear receptor subfamily 2, group C, member 2
chr6_-_50404732 0.55 ENSDART00000055510
romo1
reactive oxygen species modulator 1
chr18_-_42333428 0.55 ENSDART00000034225
cntn5
contactin 5
chr6_-_10320676 0.54 ENSDART00000151247
scn1lab
sodium channel, voltage-gated, type I like, alpha b
chr7_-_42206720 0.54 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr12_+_14084291 0.53 ENSDART00000189734
si:ch211-217a12.1
si:ch211-217a12.1
chr25_+_16214854 0.53 ENSDART00000109672
ENSDART00000190093
mical2b
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr10_+_7563755 0.50 ENSDART00000165877
purg
purine-rich element binding protein G
chr5_+_60928576 0.49 ENSDART00000131041
doc2b
double C2-like domains, beta
chr5_-_41841892 0.49 ENSDART00000167089
si:dkey-65b12.6
si:dkey-65b12.6
chr24_-_36802891 0.49 ENSDART00000088130
dcakd
dephospho-CoA kinase domain containing
chr3_-_22212764 0.48 ENSDART00000155490
maptb
microtubule-associated protein tau b
chr2_+_34767171 0.48 ENSDART00000145451
astn1
astrotactin 1
chr10_-_25561751 0.47 ENSDART00000147089
grik1a
glutamate receptor, ionotropic, kainate 1a
chr5_-_63218919 0.47 ENSDART00000149979
tecta
tectorin alpha
chr15_-_6946286 0.46 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr9_-_3653259 0.45 ENSDART00000140425
ENSDART00000025332
gad1a
glutamate decarboxylase 1a
chr12_-_47648538 0.43 ENSDART00000108477
fh
fumarate hydratase
chr7_+_42206847 0.38 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr3_-_37351225 0.38 ENSDART00000174685
si:ch211-278a6.1
si:ch211-278a6.1
chr8_-_23578660 0.37 ENSDART00000039080
wasb
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr7_+_34297271 0.37 ENSDART00000180342
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_-_16619854 0.36 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cyp21a2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr7_+_31871830 0.36 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr15_+_33691455 0.35 ENSDART00000170329
hdac12
histone deacetylase 12
chr6_+_3282809 0.35 ENSDART00000187444
ENSDART00000187407
ENSDART00000191883
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr8_-_17997845 0.34 ENSDART00000121660
acot11b
acyl-CoA thioesterase 11b
chr7_+_38588866 0.34 ENSDART00000015682
ndufs3
NADH dehydrogenase (ubiquinone) Fe-S protein 3, (NADH-coenzyme Q reductase)
chr11_+_23810148 0.32 ENSDART00000127846
nfasca
neurofascin homolog (chicken) a
chr1_-_46875493 0.31 ENSDART00000115081
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_-_21363834 0.30 ENSDART00000080051
RASSF5
si:dkey-85p17.3
chr21_-_43527198 0.29 ENSDART00000126092
irs4a
insulin receptor substrate 4a
chr17_+_30545895 0.29 ENSDART00000076739
nhsl1a
NHS-like 1a
chr3_-_18189283 0.29 ENSDART00000049240
tob1a
transducer of ERBB2, 1a
chr18_-_14922872 0.29 ENSDART00000091722
panx2
pannexin 2
chr4_-_4507761 0.29 ENSDART00000130588
tbc1d30
TBC1 domain family, member 30
chr14_+_33882973 0.28 ENSDART00000019396
clic2
chloride intracellular channel 2
chr10_+_7564106 0.28 ENSDART00000159042
purg
purine-rich element binding protein G
chr18_+_30511230 0.27 ENSDART00000078888
dusp22a
dual specificity phosphatase 22a
chr12_+_30368145 0.27 ENSDART00000153454
ccdc186
si:ch211-225b10.4
chr21_-_41369539 0.26 ENSDART00000187546
cpeb4b
cytoplasmic polyadenylation element binding protein 4b
chr16_-_25233515 0.26 ENSDART00000058943
zgc:110182
zgc:110182
chr25_-_31898552 0.26 ENSDART00000156128
si:ch73-330k17.3
si:ch73-330k17.3
chr7_-_31794878 0.26 ENSDART00000099748
nap1l4b
nucleosome assembly protein 1-like 4b
chr19_-_5332784 0.25 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr15_+_28268135 0.25 ENSDART00000152536
ENSDART00000188550
myo1cb
myosin Ic, paralog b
chr1_+_16127825 0.24 ENSDART00000122503
tusc3
tumor suppressor candidate 3
chr20_-_26936887 0.23 ENSDART00000160827
ftr79
finTRIM family, member 79
chr11_-_40647190 0.23 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
fam213b
family with sequence similarity 213, member B
chr5_-_67721368 0.22 ENSDART00000134386
arhgap31
Rho GTPase activating protein 31
chr8_-_3413139 0.22 ENSDART00000182673
ENSDART00000166741
ENSDART00000169430
ENSDART00000170478
FUT9 (1 of many)
FUT9 (1 of many)
fut9b
zgc:103510
zgc:165519
fucosyltransferase 9b
chr5_-_66301142 0.21 ENSDART00000067541
prlrb
prolactin receptor b
chr8_-_42238543 0.21 ENSDART00000062697
gfra2a
GDNF family receptor alpha 2a
chr7_+_22702437 0.20 ENSDART00000182054
si:dkey-165a24.9
si:dkey-165a24.9
chr5_-_68093169 0.20 ENSDART00000051849
slc25a11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr7_-_24005268 0.20 ENSDART00000173608
si:dkey-183c6.9
si:dkey-183c6.9
chr16_-_22294265 0.20 ENSDART00000124718
aqp10a
aquaporin 10a
chr10_-_20524387 0.20 ENSDART00000159060
ddhd2
DDHD domain containing 2
chr11_-_34166960 0.19 ENSDART00000181571
atp13a3
ATPase 13A3
chr11_-_38492564 0.18 ENSDART00000102850
elk4
ELK4, ETS-domain protein
chr3_-_45848257 0.18 ENSDART00000147198
igfals
insulin-like growth factor binding protein, acid labile subunit
chr6_+_29288223 0.17 ENSDART00000112099
zgc:172121
zgc:172121
chr7_+_38667066 0.16 ENSDART00000013394
mtch2
mitochondrial carrier homolog 2
chr3_+_39566999 0.16 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr16_-_11859309 0.16 ENSDART00000145754
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr6_-_41135215 0.15 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr18_-_4957022 0.15 ENSDART00000101686
zbbx
zinc finger, B-box domain containing
chr14_+_36628131 0.15 ENSDART00000188625
ENSDART00000125345
TENM3
si:dkey-237h12.3
chr10_+_36354863 0.13 ENSDART00000159675
or104-1
odorant receptor, family C, subfamily 104, member 1
chr21_-_41369370 0.13 ENSDART00000159290
cpeb4b
cytoplasmic polyadenylation element binding protein 4b
chr5_+_29652513 0.13 ENSDART00000035400
tsc1a
TSC complex subunit 1a
chr7_-_31794476 0.12 ENSDART00000142385
nap1l4b
nucleosome assembly protein 1-like 4b
chr8_+_13106760 0.12 ENSDART00000029308
itgb4
integrin, beta 4
chr8_-_979735 0.12 ENSDART00000149612
znf366
zinc finger protein 366
chr5_+_6670945 0.12 ENSDART00000185686
pxna
paxillin a
chr6_-_29288155 0.11 ENSDART00000078630
nme7
NME/NM23 family member 7
chr5_+_29652198 0.10 ENSDART00000184083
tsc1a
TSC complex subunit 1a
chr2_-_37312927 0.10 ENSDART00000141214
skila
SKI-like proto-oncogene a
chr13_+_43050562 0.09 ENSDART00000016602
cdh23
cadherin-related 23
chr11_-_31226578 0.09 ENSDART00000109698
nacc1b
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr12_-_850457 0.08 ENSDART00000022688
tob1b
transducer of ERBB2, 1b
chr13_+_21768447 0.08 ENSDART00000100941
chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr5_-_33959868 0.08 ENSDART00000143652
zgc:63972
zgc:63972
chr12_-_29305220 0.07 ENSDART00000153458
sh2d4bb
SH2 domain containing 4Bb
chr7_-_51775688 0.07 ENSDART00000149793
bmp15
bone morphogenetic protein 15
chr16_-_39195318 0.07 ENSDART00000058546
ebag9
estrogen receptor binding site associated, antigen, 9
chr24_+_684924 0.06 ENSDART00000186103
si:ch211-188f17.1
si:ch211-188f17.1
chr20_-_26937453 0.06 ENSDART00000139756
ftr97
finTRIM family, member 97
chr23_+_26142613 0.06 ENSDART00000165046
ptpn22
protein tyrosine phosphatase, non-receptor type 22
chr1_+_20593653 0.06 ENSDART00000132440
si:ch211-142c4.1
si:ch211-142c4.1
chr17_-_17764801 0.05 ENSDART00000155261
slirp
SRA stem-loop interacting RNA binding protein
chr11_+_12175162 0.05 ENSDART00000125446
si:ch211-156l18.7
si:ch211-156l18.7
chr4_-_18775548 0.04 ENSDART00000141187
def6c
differentially expressed in FDCP 6c homolog
chr4_-_2975461 0.04 ENSDART00000150794
plekha5
pleckstrin homology domain containing, family A member 5
chr4_-_17391091 0.03 ENSDART00000056002
th2
tyrosine hydroxylase 2
chr7_+_34296789 0.03 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_-_21067971 0.02 ENSDART00000004333
tbx15
T-box 15
chr3_+_17855981 0.02 ENSDART00000181559
BX901973.1

chr7_+_22702225 0.02 ENSDART00000173672
si:dkey-165a24.9
si:dkey-165a24.9
chr3_+_24190207 0.01 ENSDART00000034762
prr15la
proline rich 15-like a

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.6 3.1 GO:0097066 response to thyroid hormone(GO:0097066)
0.5 2.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.5 2.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.4 1.3 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.4 2.2 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.3 1.0 GO:0035902 response to immobilization stress(GO:0035902)
0.3 0.5 GO:0051193 regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196)
0.3 2.4 GO:0006833 water transport(GO:0006833)
0.2 0.9 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.2 3.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 2.0 GO:0019430 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 1.2 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.2 1.0 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 1.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.2 1.7 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.6 GO:2000379 protein import into mitochondrial inner membrane(GO:0045039) positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.1 0.8 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.2 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 2.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.6 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.5 GO:0035889 otolith tethering(GO:0035889)
0.1 0.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 2.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.8 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.0 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.2 GO:0015744 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.0 0.6 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.4 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.7 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 1.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.1 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 2.3 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005592 collagen type XI trimer(GO:0005592)
0.5 3.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.3 3.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 0.6 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 1.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.1 2.0 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.1 GO:0008305 integrin complex(GO:0008305)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.7 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.2 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 4.2 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.3 1.0 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 2.4 GO:0015250 water channel activity(GO:0015250)
0.3 2.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 1.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.6 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.7 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.2 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.5 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 1.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.0 GO:2001069 glycogen binding(GO:2001069)
0.1 0.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 2.1 GO:0005178 integrin binding(GO:0005178)
0.0 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.8 GO:0030276 clathrin binding(GO:0030276)
0.0 1.0 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 2.1 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production