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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr4a3

Z-value: 0.62

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Transcription factors associated with nr4a3

Gene Symbol Gene ID Gene Info
nr4a3
ENSDARG00000055854 nuclear receptor subfamily 4, group A, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a3dr11_v1_chr16_+_27345383_27345383-0.761.5e-04Click!

Activity profile of nr4a3 motif

Sorted Z-values of nr4a3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_16451375 3.77 ENSDART00000192700
ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr16_-_45910050 2.71 ENSDART00000133213
afp4
antifreeze protein type IV
chr22_+_14102397 2.12 ENSDART00000146397
ENSDART00000137530
he1.3
hatching enzyme 1, tandem duplicate 3
chr13_-_37127970 1.96 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr23_+_32335871 1.91 ENSDART00000149698
slc39a5
solute carrier family 39 (zinc transporter), member 5
chr8_-_40183197 1.79 ENSDART00000005118
gpx8
glutathione peroxidase 8 (putative)
chr23_+_42396934 1.73 ENSDART00000169821
cyp2aa8
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr19_-_35439237 1.69 ENSDART00000145883
anln
anillin, actin binding protein
chr5_-_14509137 1.53 ENSDART00000180742
si:ch211-244o22.2
si:ch211-244o22.2
chr4_+_15942075 1.40 ENSDART00000147964
si:dkey-117n7.2
si:dkey-117n7.2
chr22_-_14262115 1.34 ENSDART00000168264
si:ch211-246m6.5
si:ch211-246m6.5
chr21_+_8239544 1.23 ENSDART00000122773
nr6a1b
nuclear receptor subfamily 6, group A, member 1b
chr20_+_36806398 1.22 ENSDART00000153317
abracl
ABRA C-terminal like
chr8_+_39634114 1.20 ENSDART00000144293
msi1
musashi RNA-binding protein 1
chr1_-_39859626 1.20 ENSDART00000053763
dctd
dCMP deaminase
chr10_+_10351685 1.19 ENSDART00000109432
cercam
cerebral endothelial cell adhesion molecule
chr24_-_12770357 1.16 ENSDART00000060826
ipo4
importin 4
chr22_-_26100282 1.09 ENSDART00000166075
pdgfaa
platelet-derived growth factor alpha polypeptide a
chr22_-_17595310 1.07 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr17_-_28097760 1.06 ENSDART00000149861
kdm1a
lysine (K)-specific demethylase 1a
chr22_-_7050 1.04 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr6_+_7414215 1.03 ENSDART00000049339
sox21a
SRY (sex determining region Y)-box 21a
chr22_-_26005894 1.03 ENSDART00000105088
pdgfaa
platelet-derived growth factor alpha polypeptide a
chr21_-_25250594 1.01 ENSDART00000163862
nfrkb
nuclear factor related to kappaB binding protein
chr7_+_23943597 1.01 ENSDART00000157408
si:dkey-183c6.7
si:dkey-183c6.7
chr1_+_39859782 1.00 ENSDART00000149984
irf2a
interferon regulatory factor 2a
chr1_+_24557414 0.98 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr5_+_36896933 0.97 ENSDART00000151984
srsf7a
serine/arginine-rich splicing factor 7a
chr3_-_49925313 0.93 ENSDART00000164361
gcgra
glucagon receptor a
chr25_+_418932 0.92 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr23_-_16737161 0.91 ENSDART00000132573
si:ch211-224l10.4
si:ch211-224l10.4
chr9_+_500052 0.89 ENSDART00000166707
CU984600.1

chr4_-_9191220 0.87 ENSDART00000156919
hcfc2
host cell factor C2
chr8_-_22542467 0.82 ENSDART00000182588
ENSDART00000134542
csde1
cold shock domain containing E1, RNA-binding
chr25_-_35095129 0.81 ENSDART00000099866
ENSDART00000099868
kif15
kinesin family member 15
chr24_-_28419444 0.81 ENSDART00000105749
nrros
negative regulator of reactive oxygen species
chr19_-_1947403 0.81 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
znrf2a
zinc and ring finger 2a
chr1_-_57172294 0.80 ENSDART00000063774
rac1l
Rac family small GTPase 1, like
chr2_-_17115256 0.78 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr1_+_38153944 0.77 ENSDART00000135666
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr17_+_48314724 0.76 ENSDART00000125617
smoc1
SPARC related modular calcium binding 1
chr19_-_17972734 0.76 ENSDART00000126298
ints8
integrator complex subunit 8
chr8_-_21110233 0.74 ENSDART00000127371
ENSDART00000100276
tmco1
transmembrane and coiled-coil domains 1
chr4_-_77130289 0.73 ENSDART00000174380
CU467646.7

chr12_+_21697540 0.73 ENSDART00000153412
pkd1b
polycystic kidney disease 1b
chr3_+_31662126 0.72 ENSDART00000113441
mylk5
myosin, light chain kinase 5
chr11_-_6974022 0.72 ENSDART00000172851
COMP
si:ch211-43f4.1
chr10_+_8875195 0.69 ENSDART00000141045
itga2.3
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr5_-_41860556 0.69 ENSDART00000140154
si:dkey-65b12.12
si:dkey-65b12.12
chr15_+_5973909 0.68 ENSDART00000126886
ENSDART00000189618
igsf5b
immunoglobulin superfamily, member 5b
chr2_-_7246848 0.68 ENSDART00000146434
zgc:153115
zgc:153115
chr10_-_29892486 0.67 ENSDART00000099983
bsx
brain-specific homeobox
chr11_-_40681011 0.67 ENSDART00000166372
ENSDART00000110622
ENSDART00000159713
si:ch211-222l21.1
si:ch211-222l21.1
chr1_-_58868306 0.66 ENSDART00000166615
dnm2b
dynamin 2b
chr21_-_5879897 0.66 ENSDART00000184034
rpl35
ribosomal protein L35
chr4_-_77135076 0.65 ENSDART00000174184
zgc:173770
zgc:173770
chr5_+_69650148 0.65 ENSDART00000097244
gtf2h3
general transcription factor IIH, polypeptide 3
chr2_+_44977889 0.65 ENSDART00000144024
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr3_+_30501135 0.64 ENSDART00000165869
si:dkey-13n23.3
si:dkey-13n23.3
chr15_-_23206562 0.64 ENSDART00000110360
ccdc153
coiled-coil domain containing 153
chr7_+_38267136 0.64 ENSDART00000173613
gpatch1
G patch domain containing 1
chr22_-_5252005 0.64 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr2_-_41562868 0.64 ENSDART00000084597
d2hgdh
D-2-hydroxyglutarate dehydrogenase
chr23_-_24488696 0.63 ENSDART00000155593
tmem82
transmembrane protein 82
chr22_+_465269 0.62 ENSDART00000145767
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr20_+_49081967 0.61 ENSDART00000112689
crnkl1
crooked neck pre-mRNA splicing factor 1
chr2_-_36658701 0.61 ENSDART00000184995
CT027583.2

chr14_+_30413758 0.60 ENSDART00000092953
cnot7
CCR4-NOT transcription complex, subunit 7
chr25_+_3525494 0.60 ENSDART00000169775
RAB19 (1 of many)
RAB19, member RAS oncogene family
chr4_-_77135340 0.60 ENSDART00000180581
ENSDART00000179901
CU467646.7

chr20_-_36887516 0.60 ENSDART00000076313
txlnba
taxilin beta a
chr4_-_77116266 0.60 ENSDART00000174249
CU467646.2

chr2_-_56649883 0.58 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr10_+_24692076 0.58 ENSDART00000181600
tpte
transmembrane phosphatase with tensin homology
chr5_-_3839285 0.57 ENSDART00000122292
mlxipl
MLX interacting protein like
chr17_-_18888959 0.57 ENSDART00000080029
ak7b
adenylate kinase 7b
chr11_-_7410537 0.57 ENSDART00000009859
adgrl4
adhesion G protein-coupled receptor L4
chr13_+_31497236 0.56 ENSDART00000146752
lrrc9
leucine rich repeat containing 9
chr1_-_51720633 0.56 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr23_-_27607039 0.56 ENSDART00000183639
phf8
PHD finger protein 8
chr6_-_40044111 0.55 ENSDART00000154347
si:dkey-197j19.5
si:dkey-197j19.5
chr10_+_20364009 0.54 ENSDART00000186139
ENSDART00000080395
golga7
golgin A7
chr6_+_30533504 0.54 ENSDART00000155842
wwc3
WWC family member 3
chr17_-_25303486 0.54 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr20_+_19066858 0.53 ENSDART00000192086
sox7
SRY (sex determining region Y)-box 7
chr12_+_45238292 0.52 ENSDART00000057983
mrpl38
mitochondrial ribosomal protein L38
chr24_+_13869092 0.52 ENSDART00000176492
eya1
EYA transcriptional coactivator and phosphatase 1
chr1_-_52498146 0.52 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr15_+_40188076 0.52 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr22_+_15720381 0.52 ENSDART00000128149
fam32a
family with sequence similarity 32, member A
chr19_+_20787179 0.51 ENSDART00000193204
adnp2b
ADNP homeobox 2b
chr21_+_261490 0.51 ENSDART00000177919
jak2a
Janus kinase 2a
chr20_-_36887176 0.50 ENSDART00000143515
ENSDART00000146994
txlnba
taxilin beta a
chr23_+_39346930 0.50 ENSDART00000102843
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr23_-_9855627 0.50 ENSDART00000180159
prkcbp1l
protein kinase C binding protein 1, like
chr7_-_32021853 0.49 ENSDART00000134521
kif18a
kinesin family member 18A
chr13_+_7241170 0.49 ENSDART00000109434
aifm2
apoptosis-inducing factor, mitochondrion-associated, 2
chr6_-_35046735 0.49 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr19_-_47997424 0.49 ENSDART00000081675
ctnnb2
catenin, beta 2
chr21_-_15200556 0.49 ENSDART00000141809
sfswap
splicing factor SWAP
chr6_+_30703828 0.48 ENSDART00000104628
insl5a
insulin-like 5a
chr13_+_43247936 0.48 ENSDART00000126850
ENSDART00000165331
smoc2
SPARC related modular calcium binding 2
chr10_+_36441124 0.47 ENSDART00000185626
uspl1
ubiquitin specific peptidase like 1
chr3_-_34561624 0.47 ENSDART00000129313
sept9a
septin 9a
chr3_+_30500968 0.47 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr19_+_2631565 0.47 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr19_+_2877079 0.46 ENSDART00000160847
hgh1
HGH1 homolog (S. cerevisiae)
chr4_-_4535189 0.46 ENSDART00000057519
zgc:194209
zgc:194209
chr24_+_81527 0.46 ENSDART00000192139
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr9_-_33477588 0.45 ENSDART00000144150
caska
calcium/calmodulin-dependent serine protein kinase a
chr14_-_46675850 0.45 ENSDART00000113285
tapt1a
transmembrane anterior posterior transformation 1a
chr3_-_3448095 0.45 ENSDART00000078886
A2ML1 (1 of many)
si:dkey-46g23.5
chr24_-_26820698 0.44 ENSDART00000147788
fndc3bb
fibronectin type III domain containing 3Bb
chr19_+_11214007 0.44 ENSDART00000127362
si:ch73-109i22.2
si:ch73-109i22.2
chr25_-_10622449 0.44 ENSDART00000155375
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr14_-_48103207 0.44 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr20_+_19066596 0.44 ENSDART00000130271
sox7
SRY (sex determining region Y)-box 7
chr10_-_25591194 0.44 ENSDART00000131640
tiam1a
T cell lymphoma invasion and metastasis 1a
chr9_-_43142636 0.43 ENSDART00000134349
ENSDART00000181835
ccdc141
coiled-coil domain containing 141
chr15_-_25365570 0.43 ENSDART00000152754
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr23_+_39346774 0.43 ENSDART00000190985
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr3_-_26921475 0.43 ENSDART00000130281
ciita
class II, major histocompatibility complex, transactivator
chr2_-_3045861 0.43 ENSDART00000105818
ENSDART00000187575
guk1a
guanylate kinase 1a
chr9_+_23770666 0.42 ENSDART00000182493
si:ch211-219a4.3
si:ch211-219a4.3
chr7_+_22586800 0.42 ENSDART00000035325
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr25_+_21829777 0.42 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr7_-_19146925 0.42 ENSDART00000142924
ENSDART00000009695
kirrel1a
kirre like nephrin family adhesion molecule 1a
chr9_-_29985390 0.42 ENSDART00000134157
il1rapl1a
interleukin 1 receptor accessory protein-like 1a
chr16_+_17252487 0.42 ENSDART00000063572
gtf3c6
general transcription factor IIIC, polypeptide 6, alpha
chr24_+_22022109 0.41 ENSDART00000133686
ropn1l
rhophilin associated tail protein 1-like
chr5_+_29831235 0.41 ENSDART00000109660
f11r.1
F11 receptor, tandem duplicate 1
chr5_+_52167986 0.41 ENSDART00000162256
ENSDART00000073626
slc14a2
solute carrier family 14 (urea transporter), member 2
chr14_+_20941534 0.40 ENSDART00000185616
zgc:66433
zgc:66433
chr7_-_26924903 0.39 ENSDART00000124363
alx4a
ALX homeobox 4a
chr9_+_41914378 0.39 ENSDART00000130434
ENSDART00000007058
col18a1a
collagen type XVIII alpha 1 chain a
chr15_+_11840311 0.38 ENSDART00000167671
prkd2
protein kinase D2
chr23_+_24272421 0.38 ENSDART00000029974
clcnk
chloride channel K
chr6_-_54111928 0.38 ENSDART00000083880
hyal2a
hyaluronoglucosaminidase 2a
chr1_-_17650223 0.38 ENSDART00000043484
si:dkey-256e7.5
si:dkey-256e7.5
chr22_+_29113796 0.38 ENSDART00000150264
pla2g6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr8_-_52909850 0.36 ENSDART00000161943
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr16_-_19568795 0.36 ENSDART00000185141
abcb5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr22_-_15720347 0.36 ENSDART00000105692
mrpl54
mitochondrial ribosomal protein L54
chr12_+_23866368 0.36 ENSDART00000188652
ENSDART00000192478
svila
supervillin a
chr16_+_25342152 0.36 ENSDART00000156351
zfat
zinc finger and AT hook domain containing
chr12_+_47439 0.36 ENSDART00000114732
mrpl58
mitochondrial ribosomal protein L58
chr20_-_25877793 0.36 ENSDART00000177333
ENSDART00000184619
exoc1
exocyst complex component 1
chr1_-_52497834 0.36 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr12_+_46791907 0.35 ENSDART00000110304
vcla
vinculin a
chr9_+_23772516 0.35 ENSDART00000183126
si:ch211-219a4.3
si:ch211-219a4.3
chr4_-_47304459 0.35 ENSDART00000169561
si:ch211-261d9.1
si:ch211-261d9.1
chr4_-_77120928 0.35 ENSDART00000174154
CU467646.1

chr7_-_71331499 0.35 ENSDART00000081245
dhx15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr2_-_31700396 0.35 ENSDART00000142366
lrrcc1
leucine rich repeat and coiled-coil centrosomal protein 1
chr3_+_3454610 0.34 ENSDART00000024900
zgc:165453
zgc:165453
chr5_+_24156170 0.34 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr23_-_20154422 0.33 ENSDART00000132025
usp19
ubiquitin specific peptidase 19
chr1_+_13087797 0.33 ENSDART00000170314
si:dkey-5n7.2
si:dkey-5n7.2
chr9_+_9502610 0.32 ENSDART00000061525
ENSDART00000125174
nr1i2
nuclear receptor subfamily 1, group I, member 2
chr12_-_34827477 0.32 ENSDART00000153026
NDUFAF8
si:dkey-21c1.6
chr3_+_35611625 0.32 ENSDART00000190995
traf7
TNF receptor-associated factor 7
chr20_+_18260358 0.32 ENSDART00000187734
ENSDART00000191947
ENSDART00000057039
taf4b
TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr15_-_6615555 0.32 ENSDART00000152725
atm
ATM serine/threonine kinase
chr1_-_28861226 0.31 ENSDART00000075502
timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr17_-_46850299 0.30 ENSDART00000154430
pimr23
Pim proto-oncogene, serine/threonine kinase, related 23
chr18_-_48492951 0.30 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr9_+_35077546 0.30 ENSDART00000142688
si:dkey-192g7.3
si:dkey-192g7.3
chr2_+_30249977 0.30 ENSDART00000109160
ENSDART00000135171
tmem70
transmembrane protein 70
chr3_+_57825938 0.30 ENSDART00000128815
cenpx
centromere protein X
chr15_-_16946124 0.30 ENSDART00000154923
hip1
huntingtin interacting protein 1
chr12_-_29305533 0.29 ENSDART00000189410
sh2d4bb
SH2 domain containing 4Bb
chr24_-_1021318 0.29 ENSDART00000181403
ralaa
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr18_-_43866526 0.28 ENSDART00000111309
treh
trehalase (brush-border membrane glycoprotein)
chr19_-_24136233 0.28 ENSDART00000143365
thap7
THAP domain containing 7
chr20_+_37825804 0.28 ENSDART00000152865
tatdn3
TatD DNase domain containing 3
chr8_-_7440364 0.28 ENSDART00000180659
hdac6
histone deacetylase 6
chr14_+_30413312 0.28 ENSDART00000186864
cnot7
CCR4-NOT transcription complex, subunit 7
chr15_-_16884912 0.28 ENSDART00000062135
zgc:103681
zgc:103681
chr14_-_17121676 0.27 ENSDART00000170154
ENSDART00000060479
smtnl1
smoothelin-like 1
chr12_-_4185554 0.27 ENSDART00000152313
si:dkey-32n7.7
si:dkey-32n7.7
chr3_-_7129057 0.27 ENSDART00000125947
BX005085.1

chr5_+_37406358 0.26 ENSDART00000162811
klhl13
kelch-like family member 13
chr10_+_8629275 0.26 ENSDART00000129643
aplnrb
apelin receptor b
chr17_+_450956 0.26 ENSDART00000183022
ENSDART00000171386
zgc:194887
zgc:194887
chr3_-_34034498 0.26 ENSDART00000151145
ighv11-2
immunoglobulin heavy variable 11-2
chr16_-_19349318 0.25 ENSDART00000020821
dnah11
dynein, axonemal, heavy chain 11
chr13_-_44842884 0.25 ENSDART00000184195
si:dkeyp-2e4.3
si:dkeyp-2e4.3
chr3_-_32590164 0.25 ENSDART00000151151
tspan4b
tetraspanin 4b
chr1_-_14694809 0.25 ENSDART00000193331
CU138548.5

chr16_-_30927454 0.25 ENSDART00000184015
slc45a4
solute carrier family 45, member 4
chr16_+_23913943 0.24 ENSDART00000175404
ENSDART00000129525
apoa4b.1
apolipoprotein A-IV b, tandem duplicate 1
chr6_+_52924103 0.24 ENSDART00000065693
or137-2
odorant receptor, family H, subfamily 137, member 2
chr7_+_29012033 0.24 ENSDART00000173909
ENSDART00000145762
dnaaf1
dynein, axonemal, assembly factor 1
chr3_+_62317990 0.23 ENSDART00000058719
znf1124
zinc finger protein 1124
chr10_+_26645953 0.23 ENSDART00000131482
adgrg4b
adhesion G protein-coupled receptor G4b
chr19_+_1465004 0.23 ENSDART00000159157
CABZ01073736.1

chr16_+_20871021 0.23 ENSDART00000006429
hibadhb
3-hydroxyisobutyrate dehydrogenase b
chr24_-_2843107 0.22 ENSDART00000165290
cyb5a
cytochrome b5 type A (microsomal)
chr3_+_12816362 0.22 ENSDART00000163743
ENSDART00000170788
cyp2k6
cytochrome P450, family 2, subfamily K, polypeptide 6
chr16_-_30655980 0.22 ENSDART00000146508
ldlrad4b
low density lipoprotein receptor class A domain containing 4b

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.4 2.2 GO:0009219 pyrimidine deoxyribonucleotide metabolic process(GO:0009219)
0.4 1.7 GO:0008356 asymmetric cell division(GO:0008356)
0.4 2.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.3 0.9 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.3 0.8 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.2 1.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.6 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 0.7 GO:0032965 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.2 0.5 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.2 1.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 1.5 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.6 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.4 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.4 GO:0070126 mitochondrial translational termination(GO:0070126)
0.1 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.7 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.7 GO:0021982 pineal gland development(GO:0021982)
0.1 0.5 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.3 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 2.4 GO:0060030 dorsal convergence(GO:0060030)
0.1 0.2 GO:0046222 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 0.8 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.3 GO:1903589 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.1 0.4 GO:0089700 endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.1 0.7 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.4 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.1 0.5 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.8 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 0.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.4 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.4 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 3.4 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.0 1.6 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.7 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:0003314 heart rudiment morphogenesis(GO:0003314) motile cilium assembly(GO:0044458)
0.0 0.9 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.8 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.0 GO:0060840 artery development(GO:0060840)
0.0 0.5 GO:0042476 odontogenesis(GO:0042476)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1903817 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.5 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.2 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.7 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.6 GO:0051896 regulation of protein kinase B signaling(GO:0051896)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.0 GO:0072156 distal tubule morphogenesis(GO:0072156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.5 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.5 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.6 GO:0000439 core TFIIH complex(GO:0000439)
0.1 1.2 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.3 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 0.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.6 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.8 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005948 acetolactate synthase complex(GO:0005948)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 1.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.8 GO:0005657 replication fork(GO:0005657)
0.0 0.8 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.3 0.9 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3 1.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 2.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 0.9 GO:0016519 gastric inhibitory peptide receptor activity(GO:0016519)
0.2 1.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 0.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.2 0.8 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 1.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.4 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.6 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.6 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 1.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.5 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 0.6 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.5 GO:0032183 SUMO binding(GO:0032183)
0.1 0.3 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.9 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.0 GO:0002020 protease binding(GO:0002020)
0.1 0.3 GO:0047611 tubulin deacetylase activity(GO:0042903) acetylspermidine deacetylase activity(GO:0047611)
0.1 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0003984 acetolactate synthase activity(GO:0003984)
0.0 0.4 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.2 GO:0019239 deaminase activity(GO:0019239)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.3 REACTOME KINESINS Genes involved in Kinesins
0.1 1.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation