Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for nr5a1a+nr5a2+nr5a5

Z-value: 2.70

Motif logo

logo of

Transcription factors associated with nr5a1a+nr5a2+nr5a5

Gene Symbol Gene ID Gene Info
nr5a5
ENSDARG00000039116 nuclear receptor subfamily 5, group A, member 5
nr5a2
ENSDARG00000100940 nuclear receptor subfamily 5, group A, member 2
nr5a1a
ENSDARG00000103176 nuclear receptor subfamily 5, group A, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr5a5dr11_v1_chr3_-_53465223_534652490.716.0e-04Click!
nr5a2dr11_v1_chr22_-_22719440_227194400.503.0e-02Click!
nr5a1adr11_v1_chr8_-_52871056_528710560.464.8e-02Click!

Activity profile of nr5a1a+nr5a2+nr5a5 motif

Sorted Z-values of nr5a1a+nr5a2+nr5a5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_22152797 16.55 ENSDART00000145188
cyp7a1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr16_+_52512025 15.31 ENSDART00000056095
fabp10a
fatty acid binding protein 10a, liver basic
chr22_+_7439476 15.13 ENSDART00000021594
ENSDART00000063389
zgc:92041
zgc:92041
chr16_-_25085327 13.42 ENSDART00000077661
prss1
protease, serine 1
chr9_+_22003942 11.54 ENSDART00000091013
si:dkey-57a22.15
si:dkey-57a22.15
chr11_+_25472758 11.28 ENSDART00000011178
opn1sw2
opsin 1 (cone pigments), short-wave-sensitive 2
chr12_+_34896956 10.36 ENSDART00000055415
prph2a
peripherin 2a (retinal degeneration, slow)
chr6_-_39344259 9.11 ENSDART00000104074
zgc:158846
zgc:158846
chr19_-_21832441 8.81 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
mbpa
myelin basic protein a
chr17_-_12385308 8.51 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr12_-_20362041 8.12 ENSDART00000184145
ENSDART00000105952
aqp8a.2
aquaporin 8a, tandem duplicate 2
chr2_+_32780138 7.96 ENSDART00000082250
zgc:136930
zgc:136930
chr13_+_50375800 7.56 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr20_+_30939178 7.25 ENSDART00000062556
sod2
superoxide dismutase 2, mitochondrial
chr17_-_51202339 7.19 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr22_+_7439186 7.18 ENSDART00000190667
zgc:92041
zgc:92041
chr9_-_44939104 6.95 ENSDART00000192903
vil1
villin 1
chr5_-_38155005 6.59 ENSDART00000097770
gucy2d
guanylate cyclase 2D, retinal
chr9_-_44953349 6.41 ENSDART00000135156
vil1
villin 1
chr25_-_26758253 6.39 ENSDART00000123004
si:dkeyp-73b11.8
si:dkeyp-73b11.8
chr8_+_40476811 6.19 ENSDART00000129772
gck
glucokinase (hexokinase 4)
chr5_+_51594209 5.81 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
ckmt2b
creatine kinase, mitochondrial 2b (sarcomeric)
chr7_+_19904136 5.59 ENSDART00000173452
si:ch211-285j22.3
si:ch211-285j22.3
chr8_+_24854600 5.25 ENSDART00000156570
slc6a17
solute carrier family 6 (neutral amino acid transporter), member 17
chr25_+_3326885 5.21 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr5_+_27429872 5.15 ENSDART00000087894
zgc:165555
zgc:165555
chr8_+_40477264 5.10 ENSDART00000085559
gck
glucokinase (hexokinase 4)
chr16_-_43025885 5.05 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
si:dkey-7j14.5
chr15_+_20403903 4.99 ENSDART00000134182
cox7a1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr15_-_16098531 4.93 ENSDART00000080377
aldoca
aldolase C, fructose-bisphosphate, a
chr3_-_21280373 4.92 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr14_-_47314340 4.91 ENSDART00000164851
fstl5
follistatin-like 5
chr24_-_17023392 4.87 ENSDART00000106058
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr22_+_7486867 4.84 ENSDART00000034586
CELA1 (1 of many)
zgc:112302
chr8_-_21372446 4.82 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr22_+_7480465 4.77 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr9_-_44953664 4.69 ENSDART00000188558
ENSDART00000185210
vil1
villin 1
chr17_+_33226955 4.60 ENSDART00000063333
pomca
proopiomelanocortin a
chr6_-_28980756 4.59 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr22_+_7497319 4.46 ENSDART00000034564
CELA1 (1 of many)
zgc:92511
chr20_-_40754794 4.45 ENSDART00000187251
cx32.3
connexin 32.3
chr13_-_2215213 4.30 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr6_+_48618512 4.29 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr8_-_29719393 4.28 ENSDART00000077635
si:ch211-103n10.5
si:ch211-103n10.5
chr25_+_37285737 4.28 ENSDART00000126879
tmed6
transmembrane p24 trafficking protein 6
chr24_+_33802528 4.25 ENSDART00000136040
ENSDART00000147499
ENSDART00000182322
atg9b
autophagy related 9B
chr6_+_41099787 4.16 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr2_+_37110504 4.10 ENSDART00000132794
ENSDART00000042974
slc1a8b
solute carrier family 1 (glutamate transporter), member 8b
chr11_-_7320211 4.08 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr20_-_45709990 4.04 ENSDART00000027482
gpcpd1
glycerophosphocholine phosphodiesterase 1
chr11_-_10770053 4.01 ENSDART00000179213
slc4a10a
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr23_+_6272638 3.96 ENSDART00000190366
syt2a
synaptotagmin IIa
chr22_+_31821815 3.80 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr24_-_30096666 3.75 ENSDART00000183285
plppr4b
phospholipid phosphatase related 4b
chr2_-_24289641 3.74 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myh7l
myosin heavy chain 7-like
chr8_-_14052349 3.73 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr18_+_45504362 3.70 ENSDART00000140089
cngb1a
cyclic nucleotide gated channel beta 1a
chr25_+_3327071 3.70 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr16_-_12914288 3.65 ENSDART00000184221
cacng8b
calcium channel, voltage-dependent, gamma subunit 8b
chr25_+_36316280 3.65 ENSDART00000152735
si:ch211-113a14.11
si:ch211-113a14.11
chr18_-_8312848 3.64 ENSDART00000092033
mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr18_-_24996634 3.63 ENSDART00000170210
si:ch211-196l7.4
si:ch211-196l7.4
chr8_-_39903803 3.60 ENSDART00000012391
cabp1a
calcium binding protein 1a
chr22_+_7462997 3.57 ENSDART00000106082
zgc:112368
zgc:112368
chr6_+_36381709 3.55 ENSDART00000004727
rhcgl1
Rh family, C glycoprotein, like 1
chr4_+_72797711 3.53 ENSDART00000190934
ENSDART00000163236
MYRFL
myelin regulatory factor-like
chr10_-_44508249 3.52 ENSDART00000160018
DUSP26
dual specificity phosphatase 26
chr18_-_21097663 3.50 ENSDART00000060196
anpepa
alanyl (membrane) aminopeptidase a
chr8_-_53195500 3.48 ENSDART00000132000
gabrd
gamma-aminobutyric acid (GABA) A receptor, delta
chr20_+_43942278 3.47 ENSDART00000100571
clic5b
chloride intracellular channel 5b
chr22_+_7472420 3.47 ENSDART00000132049
CELA1 (1 of many)
si:dkey-57c15.4
chr17_-_7818944 3.45 ENSDART00000135538
ENSDART00000037541
rmnd1
required for meiotic nuclear division 1 homolog
chr19_-_103289 3.43 ENSDART00000143118
adgrb1b
adhesion G protein-coupled receptor B1b
chr1_+_41454210 3.43 ENSDART00000148251
si:ch211-89o9.4
si:ch211-89o9.4
chr13_-_29421331 3.42 ENSDART00000150228
chata
choline O-acetyltransferase a
chr4_-_22671469 3.40 ENSDART00000050753
cd36
CD36 molecule (thrombospondin receptor)
chr15_+_37105986 3.40 ENSDART00000157762
aplp1
amyloid beta (A4) precursor-like protein 1
chr22_+_9472814 3.37 ENSDART00000112125
ENSDART00000138850
cacna2d2b
calcium channel, voltage-dependent, alpha 2/delta subunit 2b
chr21_-_10446405 3.36 ENSDART00000167948
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr12_+_7865470 3.35 ENSDART00000161683
BX548028.1

chr10_+_466926 3.33 ENSDART00000145220
arvcfa
ARVCF, delta catenin family member a
chr20_+_25575391 3.30 ENSDART00000063108
cyp2p8
cytochrome P450, family 2, subfamily P, polypeptide 8
chr18_+_1703984 3.21 ENSDART00000114010
slitrk3a
SLIT and NTRK-like family, member 3a
chr2_+_45191049 3.16 ENSDART00000165392
ccl20a.3
chemokine (C-C motif) ligand 20a, duplicate 3
chr15_-_46718759 3.12 ENSDART00000085926
ENSDART00000154577
zgc:162872
zgc:162872
chr19_+_20724347 3.12 ENSDART00000090757
kat2b
K(lysine) acetyltransferase 2B
chr17_-_45254585 3.11 ENSDART00000185507
ENSDART00000172080
ttbk2a
tau tubulin kinase 2a
chr10_-_42685512 3.07 ENSDART00000081347
stc1l
stanniocalcin 1, like
chr12_+_45200744 3.03 ENSDART00000098932
wbp2
WW domain binding protein 2
chr3_+_61185660 3.03 ENSDART00000167114
CR352263.1

chr13_+_6342410 3.02 ENSDART00000065228
csmd1a
CUB and Sushi multiple domains 1a
chr17_-_44584811 3.01 ENSDART00000165059
ENSDART00000165252
slc35f4
solute carrier family 35, member F4
chr3_-_52614747 2.96 ENSDART00000154365
trim35-13
tripartite motif containing 35-13
chr2_-_8102169 2.96 ENSDART00000131955
pls1
plastin 1 (I isoform)
chr7_-_26087807 2.88 ENSDART00000052989
ache
acetylcholinesterase
chr8_+_19514294 2.87 ENSDART00000170622
si:ch73-281k2.5
si:ch73-281k2.5
chr2_-_42091926 2.86 ENSDART00000142663
si:dkey-97a13.12
si:dkey-97a13.12
chr1_+_45080897 2.85 ENSDART00000129819
si:ch211-151p13.8
si:ch211-151p13.8
chr24_-_20808283 2.85 ENSDART00000143759
vipr1b
vasoactive intestinal peptide receptor 1b
chr10_-_39321367 2.85 ENSDART00000129647
smtlb
somatolactin beta
chr2_-_58201173 2.84 ENSDART00000166282
pnp5b
purine nucleoside phosphorylase 5b
chr5_-_40178092 2.83 ENSDART00000146664
wdfy3
WD repeat and FYVE domain containing 3
chr6_-_35439406 2.80 ENSDART00000073784
rgs5a
regulator of G protein signaling 5a
chr20_-_27857676 2.80 ENSDART00000192934
syndig1l
synapse differentiation inducing 1-like
chr23_-_19953089 2.78 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr3_-_40301467 2.72 ENSDART00000055186
atp5mf
ATP synthase membrane subunit f
chr2_+_39108339 2.71 ENSDART00000085675
clstn2
calsyntenin 2
chr4_+_10365857 2.71 ENSDART00000138890
kcnd2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr7_+_30178253 2.71 ENSDART00000002075
si:ch211-107o10.3
si:ch211-107o10.3
chr10_-_32524771 2.70 ENSDART00000066793
dgat2
diacylglycerol O-acyltransferase 2
chr8_-_11146924 2.66 ENSDART00000126824
asb13b
ankyrin repeat and SOCS box containing 13b
chr13_-_23264724 2.63 ENSDART00000051886
si:dkey-103j14.5
si:dkey-103j14.5
chr24_+_8904135 2.60 ENSDART00000066782
gnal
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr7_+_48761646 2.57 ENSDART00000017467
acana
aggrecan a
chr21_-_30658509 2.56 ENSDART00000139764
si:dkey-22f5.9
si:dkey-22f5.9
chr1_-_19215336 2.51 ENSDART00000162949
ENSDART00000170680
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr3_-_60142530 2.51 ENSDART00000153247
si:ch211-120g10.1
si:ch211-120g10.1
chr14_+_6159162 2.49 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr11_-_29650930 2.49 ENSDART00000166969
chd5
chromodomain helicase DNA binding protein 5
chr5_-_35301800 2.48 ENSDART00000085142
map1b
microtubule-associated protein 1B
chr5_+_21891305 2.48 ENSDART00000136788
si:ch73-92i20.1
si:ch73-92i20.1
chr5_-_26936861 2.48 ENSDART00000191032
htra4
HtrA serine peptidase 4
chr12_-_32183164 2.48 ENSDART00000191269
ENSDART00000173549
SMIM36
si:ch73-256g18.2
chr22_-_21150845 2.44 ENSDART00000027345
tmem59l
transmembrane protein 59-like
chr21_-_293146 2.43 ENSDART00000157781
plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr22_+_7742211 2.43 ENSDART00000140896
CELA1 (1 of many)
zgc:92511
chr25_-_19648154 2.43 ENSDART00000148570
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr14_-_9199968 2.43 ENSDART00000146113
arhgef9b
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr1_-_54718863 2.39 ENSDART00000122601
pgam1b
phosphoglycerate mutase 1b
chr18_-_21188768 2.39 ENSDART00000060166
got2a
glutamic-oxaloacetic transaminase 2a, mitochondrial
chr25_-_35599887 2.38 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr12_+_43585527 2.37 ENSDART00000161590
clrn3
clarin 3
chr21_+_26071874 2.32 ENSDART00000003001
ENSDART00000146573
rpl23a
ribosomal protein L23a
chr14_-_47314011 2.32 ENSDART00000178523
fstl5
follistatin-like 5
chr4_-_20039635 2.31 ENSDART00000179191
BX855618.1

chr7_-_72208248 2.31 ENSDART00000108916
zmp:0000001168
zmp:0000001168
chr8_+_23213320 2.30 ENSDART00000032996
ENSDART00000137536
ppdpfa
pancreatic progenitor cell differentiation and proliferation factor a
chr7_+_67494107 2.30 ENSDART00000185653
cpne7
copine VII
chr3_+_1182315 2.30 ENSDART00000055430
ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr22_+_15323930 2.30 ENSDART00000142416
si:dkey-236e20.3
si:dkey-236e20.3
chr8_-_39739056 2.25 ENSDART00000147992
si:ch211-170d8.5
si:ch211-170d8.5
chr12_-_45304971 2.25 ENSDART00000186537
ENSDART00000126405
fdxr
ferredoxin reductase
chr11_+_30663300 2.25 ENSDART00000161662
ttbk1a
tau tubulin kinase 1a
chr11_-_28911172 2.25 ENSDART00000168493
igsf21a
immunoglobin superfamily, member 21a
chr4_+_11375894 2.23 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr14_-_31060082 2.22 ENSDART00000111601
ENSDART00000161113
mbnl3
muscleblind-like splicing regulator 3
chr25_+_25124684 2.21 ENSDART00000167542
ldha
lactate dehydrogenase A4
chr19_-_5103313 2.21 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr14_+_5936996 2.18 ENSDART00000097144
ENSDART00000126777
kctd8
potassium channel tetramerization domain containing 8
chr1_+_41690402 2.17 ENSDART00000177298
fbxo41
F-box protein 41
chr13_-_20540790 2.17 ENSDART00000131467
si:ch1073-126c3.2
si:ch1073-126c3.2
chr2_-_37967368 2.16 ENSDART00000050345
cbln9
cerebellin 9
chr24_-_17029374 2.16 ENSDART00000039267
ptgdsb.1
prostaglandin D2 synthase b, tandem duplicate 1
chr17_-_31058900 2.15 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
eml1
echinoderm microtubule associated protein like 1
chr22_-_12862415 2.11 ENSDART00000145156
ENSDART00000137280
glsa
glutaminase a
chr12_+_32323098 2.10 ENSDART00000188722
ANKFN1
si:ch211-277e21.2
chr7_+_568819 2.09 ENSDART00000173716
nrxn2b
neurexin 2b
chr18_-_8885792 2.09 ENSDART00000143619
si:dkey-95h12.1
si:dkey-95h12.1
chr3_+_442570 2.08 ENSDART00000058099
si:ch73-308m11.1
si:ch73-308m11.1
chr2_-_19109304 2.03 ENSDART00000168028
si:dkey-225f23.5
si:dkey-225f23.5
chr10_-_29101715 2.02 ENSDART00000149674
ENSDART00000171194
ENSDART00000192019
si:ch211-103f14.3
si:ch211-103f14.3
chr6_-_29195642 1.98 ENSDART00000078625
dpt
dermatopontin
chr25_-_10564721 1.97 ENSDART00000154776
galn
galanin/GMAP prepropeptide
chr6_-_50404732 1.97 ENSDART00000055510
romo1
reactive oxygen species modulator 1
chr15_-_7598542 1.94 ENSDART00000173092
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr19_-_7406933 1.92 ENSDART00000151137
oxr1b
oxidation resistance 1b
chr14_-_36412473 1.92 ENSDART00000128244
ENSDART00000138376
asb5a
ankyrin repeat and SOCS box containing 5a
chr20_+_4392687 1.90 ENSDART00000187271
im:7142702
im:7142702
chr2_-_11468654 1.90 ENSDART00000131229
slc44a5a
solute carrier family 44, member 5a
chr25_-_13188678 1.89 ENSDART00000125754
si:ch211-147m6.1
si:ch211-147m6.1
chr19_-_5103141 1.87 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr15_+_45994123 1.87 ENSDART00000124704
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr2_+_45552901 1.86 ENSDART00000131701
fndc7a
fibronectin type III domain containing 7a
chr23_-_18287618 1.85 ENSDART00000112735
fam19a1a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1a
chr15_-_7598294 1.85 ENSDART00000165898
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr25_+_8407892 1.83 ENSDART00000153536
muc5.2
mucin 5.2
chr19_+_47311020 1.83 ENSDART00000138295
ext1c
exostoses (multiple) 1c
chr10_+_42374770 1.83 ENSDART00000020000
COX5B
zgc:86599
chr21_+_5882300 1.82 ENSDART00000165065
uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr10_+_19338255 1.82 ENSDART00000113737
lrrtm4l1
leucine rich repeat transmembrane neuronal 4 like 1
chr14_+_8343498 1.79 ENSDART00000164551
nrg2b
neuregulin 2b
chr5_-_42544522 1.76 ENSDART00000157968
BX510949.1

chr11_-_25213651 1.76 ENSDART00000097316
ENSDART00000152186
myh7ba
myosin, heavy chain 7B, cardiac muscle, beta a
chr24_-_31846366 1.76 ENSDART00000155295
steap2
STEAP family member 2, metalloreductase
chr13_-_3370638 1.75 ENSDART00000029649
prkn
parkin RBR E3 ubiquitin protein ligase
chr23_+_27756984 1.73 ENSDART00000137103
kmt2d
lysine (K)-specific methyltransferase 2D
chr17_-_3303805 1.73 ENSDART00000169136
CABZ01007222.1

chr3_+_43460696 1.72 ENSDART00000164581
galr2b
galanin receptor 2b
chr3_+_55288200 1.69 ENSDART00000157002
ENSDART00000155600
si:dkey-114l24.2
si:dkey-114l24.2
chr1_-_26782573 1.69 ENSDART00000090611
sh3gl2a
SH3 domain containing GRB2 like 2a, endophilin A1
chr10_-_16028082 1.68 ENSDART00000122540
aldh7a1
aldehyde dehydrogenase 7 family, member A1
chr1_+_55662491 1.67 ENSDART00000152386
adgre8
adhesion G protein-coupled receptor E8
chr10_-_23358357 1.64 ENSDART00000135475
cadm2a
cell adhesion molecule 2a
chr5_-_38064065 1.64 ENSDART00000137181
si:dkey-111e8.5
si:dkey-111e8.5
chr1_+_44711446 1.63 ENSDART00000193481
ENSDART00000003895
ssrp1b
structure specific recognition protein 1b
chr25_+_5604512 1.62 ENSDART00000042781
plxnb2b
plexin b2b
chr22_+_38194151 1.61 ENSDART00000121965
cp
ceruloplasmin
chr11_+_2855430 1.61 ENSDART00000172837
kif21b
kinesin family member 21B
chr22_-_34551568 1.60 ENSDART00000148147
rnf123
ring finger protein 123
chr22_-_31517300 1.60 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b

Network of associatons between targets according to the STRING database.

First level regulatory network of nr5a1a+nr5a2+nr5a5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 18.0 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
2.8 16.5 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
1.8 5.3 GO:0015824 proline transport(GO:0015824)
1.6 6.3 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
1.1 11.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
1.0 3.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
1.0 4.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.9 3.4 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.9 3.4 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.8 5.0 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.8 3.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.7 7.2 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.7 2.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.7 2.6 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.6 8.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.6 8.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.6 2.4 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.6 3.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.6 2.4 GO:0006531 aspartate metabolic process(GO:0006531)
0.6 4.1 GO:0034389 lipid particle organization(GO:0034389)
0.5 2.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.5 6.3 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.4 1.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.4 3.5 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.4 1.8 GO:0015677 copper ion import(GO:0015677)
0.4 2.6 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.4 3.4 GO:0044539 response to vitamin(GO:0033273) long-chain fatty acid import(GO:0044539)
0.4 4.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 1.4 GO:2000048 negative regulation of cell-substrate adhesion(GO:0010812) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 4.1 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.3 3.4 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.3 2.7 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.3 1.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.7 GO:0071800 podosome assembly(GO:0071800)
0.3 1.3 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.3 6.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.3 2.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.3 2.8 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.2 1.2 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.2 0.7 GO:0035889 otolith tethering(GO:0035889)
0.2 4.3 GO:0016584 nucleosome positioning(GO:0016584)
0.2 1.4 GO:0032218 riboflavin transport(GO:0032218)
0.2 1.2 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.2 11.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 1.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 2.2 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 3.7 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.2 1.3 GO:0005513 detection of calcium ion(GO:0005513)
0.2 4.6 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.2 4.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 0.6 GO:0035973 aggrephagy(GO:0035973)
0.2 1.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 1.7 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.2 1.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 1.1 GO:0016559 peroxisome fission(GO:0016559)
0.2 0.7 GO:0014909 smooth muscle cell migration(GO:0014909)
0.2 2.5 GO:0031114 neural plate development(GO:0001840) regulation of microtubule depolymerization(GO:0031114)
0.2 3.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 4.0 GO:0015701 bicarbonate transport(GO:0015701)
0.2 0.7 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.2 1.2 GO:0032475 otolith formation(GO:0032475)
0.2 1.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 3.9 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 1.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.2 0.8 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 4.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.0 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.5 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 25.5 GO:0007601 visual perception(GO:0007601)
0.1 3.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 3.5 GO:0043171 peptide catabolic process(GO:0043171)
0.1 2.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 5.9 GO:0051592 response to calcium ion(GO:0051592)
0.1 2.3 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 8.8 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 6.5 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 2.4 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 2.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.6 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.1 5.5 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 3.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 1.6 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 3.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 3.8 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 2.3 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.8 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 2.4 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.0 GO:0006825 copper ion transport(GO:0006825)
0.1 2.0 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.5 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 12.5 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 2.0 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 1.2 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.1 1.6 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 1.2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.6 GO:0072348 sulfur compound transport(GO:0072348)
0.1 5.9 GO:0051260 protein homooligomerization(GO:0051260)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 4.1 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.4 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.9 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 2.3 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 5.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 4.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 3.6 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.1 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.8 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.4 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 2.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.4 GO:0035148 tube formation(GO:0035148)
0.0 2.2 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.6 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.2 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 1.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.9 GO:0006096 glycolytic process(GO:0006096)
0.0 3.6 GO:0048675 axon extension(GO:0048675)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 1.6 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.7 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 2.4 GO:0006457 protein folding(GO:0006457)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 4.3 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.3 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 2.2 GO:0051216 cartilage development(GO:0051216)
0.0 2.7 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 1.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 1.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.0 GO:0007060 male meiosis chromosome segregation(GO:0007060)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 18.0 GO:0032433 filopodium tip(GO:0032433)
1.4 8.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.8 9.1 GO:0045095 keratin filament(GO:0045095)
0.8 2.4 GO:1902560 GMP reductase complex(GO:1902560)
0.8 4.0 GO:0042584 chromaffin granule membrane(GO:0042584)
0.6 4.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.5 8.8 GO:0043209 myelin sheath(GO:0043209)
0.4 1.2 GO:0098753 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.3 1.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 11.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 1.7 GO:0001891 phagocytic cup(GO:0001891)
0.2 2.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 2.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 2.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2 0.9 GO:0098803 respiratory chain complex IV(GO:0045277) cytochrome complex(GO:0070069) respiratory chain complex(GO:0098803)
0.2 1.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 3.0 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.2 4.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.6 GO:0035101 FACT complex(GO:0035101)
0.1 1.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 9.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 4.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 13.4 GO:0000786 nucleosome(GO:0000786)
0.1 1.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 7.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.7 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.1 7.8 GO:0005882 intermediate filament(GO:0005882)
0.1 3.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 2.7 GO:0043204 perikaryon(GO:0043204)
0.1 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 2.7 GO:0016605 PML body(GO:0016605)
0.1 2.3 GO:0035869 ciliary transition zone(GO:0035869)
0.1 4.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 4.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 1.2 GO:0031430 M band(GO:0031430)
0.1 1.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 3.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 3.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 5.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 3.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 17.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 5.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 3.3 GO:0016459 myosin complex(GO:0016459)
0.0 1.5 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 47.7 GO:0005576 extracellular region(GO:0005576)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.2 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.6 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 25.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.6 GO:0005912 adherens junction(GO:0005912)
0.0 1.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 15.3 GO:0032052 bile acid binding(GO:0032052)
1.9 11.3 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.6 11.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.5 4.6 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
1.3 4.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
1.1 4.3 GO:0005521 lamin binding(GO:0005521)
1.0 4.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
1.0 4.1 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.9 2.8 GO:0070186 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.9 3.8 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.9 7.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.9 8.1 GO:0015250 water channel activity(GO:0015250)
0.8 3.4 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.8 2.4 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.6 2.4 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.6 8.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 2.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.5 2.7 GO:0008432 JUN kinase binding(GO:0008432)
0.5 2.6 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.5 6.3 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.5 2.9 GO:0004104 cholinesterase activity(GO:0004104)
0.5 13.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5 2.4 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.5 2.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.5 1.8 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.5 2.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 1.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.4 1.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 1.2 GO:0004904 interferon receptor activity(GO:0004904)
0.4 3.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.4 6.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.4 1.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 18.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3 2.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 2.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 4.0 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.3 8.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 17.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3 1.7 GO:0004966 galanin receptor activity(GO:0004966)
0.3 4.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 2.7 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.3 2.2 GO:0001972 retinoic acid binding(GO:0001972)
0.3 1.3 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.3 3.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.2 2.1 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 1.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 11.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.9 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.2 8.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 4.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 3.4 GO:0030552 cAMP binding(GO:0030552)
0.2 0.7 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.2 1.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2 1.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 0.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 12.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 3.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.7 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 1.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 3.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.9 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 2.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.5 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.4 GO:0000996 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 4.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 2.9 GO:0005112 Notch binding(GO:0005112)
0.1 3.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 4.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 4.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 3.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.6 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.1 2.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 3.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 7.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 3.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.3 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 5.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 1.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 16.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 1.6 GO:0031491 nucleosome binding(GO:0031491)
0.1 3.5 GO:0005254 chloride channel activity(GO:0005254)
0.1 5.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 1.6 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 5.7 GO:0015293 symporter activity(GO:0015293)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 7.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 3.0 GO:0008201 heparin binding(GO:0008201)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 3.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 1.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 2.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.9 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 1.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 1.3 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.4 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 4.8 GO:0051015 actin filament binding(GO:0051015)
0.0 1.2 GO:0042802 identical protein binding(GO:0042802)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.6 PID CONE PATHWAY Visual signal transduction: Cones
0.3 13.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 4.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 2.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 3.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.5 PID REELIN PATHWAY Reelin signaling pathway
0.1 18.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 3.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.1 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 16.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
1.9 13.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.6 2.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.5 10.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 3.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 2.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 2.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 11.2 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 2.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.7 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 1.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.7 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 3.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 3.4 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 3.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis