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PRJEB1986: zebrafish developmental stages transcriptome

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Results for nr6a1b

Z-value: 1.40

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Transcription factors associated with nr6a1b

Gene Symbol Gene ID Gene Info
nr6a1b
ENSDARG00000014480 nuclear receptor subfamily 6, group A, member 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr6a1bdr11_v1_chr21_+_8239544_8239544-0.795.1e-05Click!

Activity profile of nr6a1b motif

Sorted Z-values of nr6a1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_5135345 9.25 ENSDART00000151787
gnb3b
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr5_-_50992690 7.11 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr3_+_13469704 6.31 ENSDART00000166806
zgc:77748
zgc:77748
chr21_+_11401247 5.30 ENSDART00000143952
cel.1
carboxyl ester lipase, tandem duplicate 1
chr3_+_39540014 4.89 ENSDART00000074848
zgc:165423
zgc:165423
chr20_+_9128829 4.64 ENSDART00000064144
ENSDART00000137450
bpnt1
bisphosphate nucleotidase 1
chr2_-_37210397 4.56 ENSDART00000084938
apoda.1
apolipoprotein Da, duplicate 1
chr25_+_14092871 4.54 ENSDART00000067239
guca1g
guanylate cyclase activator 1g
chr3_+_19299309 3.91 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr15_+_19682013 3.65 ENSDART00000127368
si:dkey-4p15.5
si:dkey-4p15.5
chr25_-_210730 3.48 ENSDART00000187580
FP236318.1

chr25_+_7492663 3.39 ENSDART00000166496
cat
catalase
chr20_+_4392687 3.39 ENSDART00000187271
im:7142702
im:7142702
chr2_+_52232630 3.35 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr11_+_45287541 3.33 ENSDART00000165321
ENSDART00000173116
pycr1b
pyrroline-5-carboxylate reductase 1b
chr20_+_13175379 3.18 ENSDART00000025644
ppp2r5a
protein phosphatase 2, regulatory subunit B', alpha isoform
chr12_+_33395748 3.12 ENSDART00000129458
fasn
fatty acid synthase
chr10_-_17284055 3.09 ENSDART00000167464
GNAZ
G protein subunit alpha z
chr25_+_33939728 3.07 ENSDART00000148537
roraa
RAR-related orphan receptor A, paralog a
chr25_-_225964 3.01 ENSDART00000193424
CABZ01113818.1

chr23_-_19230627 2.96 ENSDART00000007122
guca1b
guanylate cyclase activator 1B
chr5_+_6892195 2.95 ENSDART00000048201
gb:cr929477
expressed sequence CR929477
chr6_+_40671336 2.81 ENSDART00000111639
ENSDART00000186617
rereb
arginine-glutamic acid dipeptide (RE) repeats b
chr10_-_16868211 2.63 ENSDART00000171755
stoml2
stomatin (EPB72)-like 2
chr1_-_55785722 2.63 ENSDART00000142069
ENSDART00000043933
ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr4_+_7827261 2.60 ENSDART00000129568
phyh
phytanoyl-CoA 2-hydroxylase
chr6_+_39836474 2.59 ENSDART00000112637
smarcc2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr13_-_22843562 2.54 ENSDART00000142738
pbld
phenazine biosynthesis like protein domain containing
chr6_+_48618512 2.52 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr6_+_39506043 2.43 ENSDART00000086260
CR388364.1

chr15_+_46386261 2.40 ENSDART00000191793
igsf11
immunoglobulin superfamily member 11
chr1_-_46632948 2.34 ENSDART00000148893
ENSDART00000053232
cdadc1
cytidine and dCMP deaminase domain containing 1
chr3_-_40976463 2.28 ENSDART00000128450
ENSDART00000018676
cyp3c1
cytochrome P450, family 3, subfamily c, polypeptide 1
chr17_+_18117358 2.26 ENSDART00000144894
bcl11ba
B cell CLL/lymphoma 11Ba
chr6_+_41099787 2.26 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr7_+_19482084 2.24 ENSDART00000173873
si:ch211-212k18.7
si:ch211-212k18.7
chr6_-_47246948 2.20 ENSDART00000162435
grm4
glutamate receptor, metabotropic 4
chr12_+_46605600 2.19 ENSDART00000123533
FADS6
fatty acid desaturase 6
chr15_+_19681718 2.16 ENSDART00000164803
si:dkey-4p15.5
si:dkey-4p15.5
chr23_-_19953089 2.07 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr4_-_17409533 1.99 ENSDART00000011943
pah
phenylalanine hydroxylase
chr24_-_25574967 1.98 ENSDART00000189828
cnksr2a
connector enhancer of kinase suppressor of Ras 2a
chr16_+_23811554 1.85 ENSDART00000114336
si:dkey-7f3.9
si:dkey-7f3.9
chr4_-_63166758 1.83 ENSDART00000192765
CR450780.1

chr19_+_20724347 1.82 ENSDART00000090757
kat2b
K(lysine) acetyltransferase 2B
chr10_-_29120515 1.77 ENSDART00000162016
ENSDART00000149140
zpld1a
zona pellucida-like domain containing 1a
chr20_-_53435483 1.75 ENSDART00000135091
mettl24
methyltransferase like 24
chr3_+_1749793 1.73 ENSDART00000149308
si:dkeyp-52c3.7
si:dkeyp-52c3.7
chr1_+_17527342 1.62 ENSDART00000139702
ENSDART00000140076
ENSDART00000005593
casp3a
caspase 3, apoptosis-related cysteine peptidase a
chr8_-_49908978 1.58 ENSDART00000172642
agtpbp1
ATP/GTP binding protein 1
chr4_-_34480599 1.57 ENSDART00000159602
ENSDART00000182248
si:dkeyp-51g9.4
si:ch211-64i20.3
si:dkeyp-51g9.4
si:ch211-64i20.3
chr6_-_30932078 1.51 ENSDART00000028612
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr18_+_8340886 1.49 ENSDART00000081132
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr25_-_21609645 1.48 ENSDART00000087817
DOCK4 (1 of many)
si:dkey-81e3.1
chr4_-_34776147 1.41 ENSDART00000167498
si:dkey-146m20.14
si:dkey-146m20.14
chr23_-_24450686 1.40 ENSDART00000189161
spen
spen family transcriptional repressor
chr24_-_10394277 1.39 ENSDART00000127568
ankha
ANKH inorganic pyrophosphate transport regulator a
chr2_+_38924975 1.34 ENSDART00000109219
rem2
RAS (RAD and GEM)-like GTP binding 2
chr21_-_43040780 1.34 ENSDART00000187037
jakmip2
janus kinase and microtubule interacting protein 2
chr17_+_33311784 1.31 ENSDART00000156229
si:ch211-132f19.7
si:ch211-132f19.7
chr21_+_43669943 1.29 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr13_-_21688176 1.23 ENSDART00000063825
sprn
shadow of prion protein
chr12_-_18408566 1.13 ENSDART00000078767
ENSDART00000152748
tom1l2
target of myb1 like 2 membrane trafficking protein
chr10_+_25219728 1.12 ENSDART00000193829
grm5a
glutamate receptor, metabotropic 5a
chr7_-_16237861 1.07 ENSDART00000173647
btr07
bloodthirsty-related gene family, member 7
chr8_-_23578660 1.06 ENSDART00000039080
wasb
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr21_-_32374656 1.04 ENSDART00000112550
mapk9
mitogen-activated protein kinase 9
chr16_+_14216581 0.99 ENSDART00000113093
gba
glucosidase, beta, acid
chr3_-_40976288 0.94 ENSDART00000193553
cyp3c1
cytochrome P450, family 3, subfamily c, polypeptide 1
chr17_+_18117029 0.91 ENSDART00000154646
ENSDART00000179739
bcl11ba
B cell CLL/lymphoma 11Ba
chr8_+_22472584 0.86 ENSDART00000138303
si:dkey-23c22.9
si:dkey-23c22.9
chr15_-_41720173 0.79 ENSDART00000155585
ENSDART00000075909
ftr76
finTRIM family, member 76
chr4_+_34119824 0.78 ENSDART00000165637
si:ch211-223g7.6
si:ch211-223g7.6
chr15_+_22722684 0.77 ENSDART00000156760
grik4
glutamate receptor, ionotropic, kainate 4
chr24_-_25256230 0.74 ENSDART00000155780
hhla2b.1
HERV-H LTR-associating 2b, tandem duplicate 1
chr4_-_70263609 0.73 ENSDART00000163868
si:dkey-3h2.3
si:dkey-3h2.3
chr4_-_71267461 0.67 ENSDART00000161219
ENSDART00000151838
si:dkeyp-51g9.4
si:dkeyp-51g9.4
chr7_-_15370042 0.67 ENSDART00000128183
ANPEP
si:ch211-276a23.5
chr4_+_9836465 0.67 ENSDART00000004879
hsp90b1
heat shock protein 90, beta (grp94), member 1
chr9_+_42270043 0.66 ENSDART00000137435
si:dkey-10c21.1
si:dkey-10c21.1
chr15_+_44133972 0.65 ENSDART00000157846
ENSDART00000191082
CU655961.2

chr25_-_29415369 0.64 ENSDART00000110774
ENSDART00000019183
ugt5a2
ugt5a1
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr22_-_17781213 0.62 ENSDART00000137984
si:ch73-63e15.2
si:ch73-63e15.2
chr1_-_49947482 0.61 ENSDART00000143398
sgms2
sphingomyelin synthase 2
chr7_-_31618166 0.60 ENSDART00000111388
igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr7_-_1918971 0.60 ENSDART00000181759
CABZ01040626.1

chr4_-_38829098 0.59 ENSDART00000151932
si:dkey-59l11.10
si:dkey-59l11.10
chr4_-_63559311 0.58 ENSDART00000164415
si:dkey-16p6.1
si:dkey-16p6.1
chr4_-_47096170 0.58 ENSDART00000161079
si:dkey-26m3.3
si:dkey-26m3.3
chr3_+_2669813 0.53 ENSDART00000014205
CR388047.1

chr4_-_49582758 0.53 ENSDART00000180834
ENSDART00000187608
si:dkey-159n16.2
si:dkey-159n16.2
chr7_+_35268054 0.53 ENSDART00000113842
dpep2
dipeptidase 2
chr8_+_18044257 0.51 ENSDART00000029255
glis1b
GLIS family zinc finger 1b
chr3_-_39627412 0.51 ENSDART00000123292
si:dkey-27o4.1
si:dkey-27o4.1
chr12_+_30788912 0.51 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr3_+_12652244 0.50 ENSDART00000165980
abca3b
ATP-binding cassette, sub-family A (ABC1), member 3b
chr4_-_44509477 0.49 ENSDART00000102949
ENSDART00000135262
si:dkeyp-100h4.1
si:dkeyp-100h4.1
chr20_+_36730049 0.49 ENSDART00000045948
ncoa1
nuclear receptor coactivator 1
chr2_-_22286828 0.48 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr11_-_5563498 0.46 ENSDART00000160835
pex11g
peroxisomal biogenesis factor 11 gamma
chr12_+_387850 0.45 ENSDART00000182326
gsg1l2b
gsg1-like 2b
chr3_+_32112004 0.45 ENSDART00000105272
zgc:173593
zgc:173593
chr17_-_39786222 0.44 ENSDART00000154515
pimr62
Pim proto-oncogene, serine/threonine kinase, related 62
chr18_+_8912113 0.42 ENSDART00000147467
tmem243a
transmembrane protein 243, mitochondrial a
chr4_+_76973771 0.39 ENSDART00000142978
si:dkey-240n22.3
si:dkey-240n22.3
chr2_+_44687147 0.38 ENSDART00000141605
yeats2
YEATS domain containing 2
chr16_+_49249669 0.34 ENSDART00000181899
LO018128.1

chr17_-_40956035 0.33 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr10_-_373575 0.33 ENSDART00000114487
DMPK
DM1 protein kinase
chr5_+_1079423 0.30 ENSDART00000172231
si:zfos-128g4.2
si:zfos-128g4.2
chr4_-_47095583 0.21 ENSDART00000183595
ENSDART00000183279
ENSDART00000191638
si:dkey-26m3.3
si:dkey-26m3.3
chr19_+_30662529 0.20 ENSDART00000175662
fam49al
family with sequence similarity 49, member A-like
chr4_+_47782411 0.19 ENSDART00000161728
si:ch211-196h24.2
si:ch211-196h24.2
chr19_+_7878122 0.18 ENSDART00000131917
si:dkeyp-85e10.2
si:dkeyp-85e10.2
chr19_+_5135113 0.16 ENSDART00000151310
si:dkey-89b17.4
si:dkey-89b17.4
chr17_-_37054959 0.16 ENSDART00000151921
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr7_-_20453661 0.13 ENSDART00000174001
ntn5
netrin 5
chr4_-_34775762 0.08 ENSDART00000167262
si:dkey-146m20.14
si:dkey-146m20.14
chr12_-_30583668 0.07 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr11_-_17964525 0.06 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr4_-_71470455 0.02 ENSDART00000172685
si:ch211-76m11.5
si:ch211-76m11.5
chr1_-_49947290 0.01 ENSDART00000141476
sgms2
sphingomyelin synthase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of nr6a1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.6 1.8 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.5 5.3 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.4 1.3 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.4 3.8 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.4 1.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.4 1.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.4 2.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 6.3 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.3 1.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.2 4.6 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.2 3.4 GO:0046688 response to copper ion(GO:0046688)
0.2 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 2.0 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.2 3.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 4.6 GO:0007568 aging(GO:0007568)
0.1 1.5 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 2.4 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.7 GO:0035889 otolith tethering(GO:0035889)
0.1 3.1 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.1 0.5 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 2.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 3.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 2.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.3 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.6 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 3.0 GO:0007601 visual perception(GO:0007601)
0.0 1.0 GO:0007254 JNK cascade(GO:0007254)
0.0 6.8 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 0.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 7.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 2.6 GO:0071564 npBAF complex(GO:0071564)
0.1 8.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 3.4 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.2 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 6.8 GO:0009986 cell surface(GO:0009986)
0.0 1.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 2.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0004771 sterol esterase activity(GO:0004771)
1.0 3.9 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.9 7.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.7 3.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.6 9.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.6 2.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 2.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 3.4 GO:0004096 catalase activity(GO:0004096)
0.3 1.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.2 1.8 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 2.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.2 1.5 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 4.6 GO:0008252 nucleotidase activity(GO:0008252)
0.2 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 3.2 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 1.1 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 2.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 3.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 7.1 GO:0050661 NADP binding(GO:0050661)
0.1 2.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 1.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 2.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 1.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 7.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.9 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 3.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 2.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 3.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.9 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 3.0 PID CONE PATHWAY Visual signal transduction: Cones
0.2 2.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 3.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.2 6.2 PID FOXO PATHWAY FoxO family signaling
0.1 3.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 3.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.7 3.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 2.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 3.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 3.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 1.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 3.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives