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PRJEB1986: zebrafish developmental stages transcriptome

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Results for onecut2

Z-value: 0.65

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Transcription factors associated with onecut2

Gene Symbol Gene ID Gene Info
onecut2
ENSDARG00000090387 one cut homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
onecut2dr11_v1_chr21_-_1742159_17421590.522.3e-02Click!

Activity profile of onecut2 motif

Sorted Z-values of onecut2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_15266093 2.77 ENSDART00000124676
sv2ba
synaptic vesicle glycoprotein 2Ba
chr11_-_11518469 2.36 ENSDART00000104254
krt15
keratin 15
chr12_-_22524388 2.26 ENSDART00000020942
shbg
sex hormone-binding globulin
chr3_-_28120092 2.20 ENSDART00000151143
rbfox1
RNA binding fox-1 homolog 1
chr17_-_25737452 2.15 ENSDART00000152021
si:ch211-214p16.3
si:ch211-214p16.3
chr8_-_23081511 2.10 ENSDART00000142015
ENSDART00000135764
ENSDART00000147021
si:dkey-70p6.1
si:dkey-70p6.1
chr5_-_29643930 2.08 ENSDART00000161250
grin1b
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr25_+_7229046 1.93 ENSDART00000149965
ENSDART00000041820
lingo1a
leucine rich repeat and Ig domain containing 1a
chr2_-_32505091 1.92 ENSDART00000141884
ENSDART00000056639
faim2a
Fas apoptotic inhibitory molecule 2a
chr6_+_3828560 1.87 ENSDART00000185273
ENSDART00000179091
gad1b
glutamate decarboxylase 1b
chr1_-_21409877 1.83 ENSDART00000102782
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr25_-_9805269 1.73 ENSDART00000192048
lrrc4c
leucine rich repeat containing 4C
chr20_-_40755614 1.57 ENSDART00000061247
cx32.3
connexin 32.3
chr18_+_15644559 1.43 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr18_+_642889 1.40 ENSDART00000189007
CABZ01078320.1

chr16_-_13612650 1.34 ENSDART00000080372
dbpb
D site albumin promoter binding protein b
chr20_-_40754794 1.30 ENSDART00000187251
cx32.3
connexin 32.3
chr14_-_2348917 1.27 ENSDART00000159004
si:ch73-233f7.8
si:ch73-233f7.8
chr18_-_37007294 1.25 ENSDART00000088309
map3k10
mitogen-activated protein kinase kinase kinase 10
chr7_+_49877148 1.25 ENSDART00000174182
slc1a2a
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr16_-_44127307 1.25 ENSDART00000104583
ENSDART00000151936
ENSDART00000058685
ENSDART00000190830
zfpm2a
zinc finger protein, FOG family member 2a
chr5_+_27267186 1.22 ENSDART00000182238
ENSDART00000087857
unc5db
unc-5 netrin receptor Db
chr2_+_7818368 1.22 ENSDART00000007068
kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr17_-_45247332 1.20 ENSDART00000016815
ttbk2a
tau tubulin kinase 2a
chr18_+_50890749 1.18 ENSDART00000174109
si:ch1073-450f2.1
si:ch1073-450f2.1
chr4_+_7827261 1.14 ENSDART00000129568
phyh
phytanoyl-CoA 2-hydroxylase
chr18_-_37007061 1.13 ENSDART00000136432
map3k10
mitogen-activated protein kinase kinase kinase 10
chr16_+_5612547 1.12 ENSDART00000140226
ENSDART00000189352
CYTH2
si:dkey-283b15.4
chr4_-_8903240 1.04 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr8_-_37263524 1.04 ENSDART00000061327
rh50
Rh50-like protein
chr8_+_40477264 1.02 ENSDART00000085559
gck
glucokinase (hexokinase 4)
chr18_+_50276653 1.02 ENSDART00000192120
si:dkey-105e17.1
si:dkey-105e17.1
chr21_-_27881752 1.01 ENSDART00000132583
nrxn2a
neurexin 2a
chr18_+_50276337 1.00 ENSDART00000140352
si:dkey-105e17.1
si:dkey-105e17.1
chr5_+_61301525 0.99 ENSDART00000128773
doc2b
double C2-like domains, beta
chr7_-_41693004 0.95 ENSDART00000121509
malrd1
MAM and LDL receptor class A domain containing 1
chr4_-_10599062 0.95 ENSDART00000048003
tspan12
tetraspanin 12
chr5_-_65158203 0.85 ENSDART00000171656
sh2d3cb
SH2 domain containing 3Cb
chr8_-_45279411 0.83 ENSDART00000175207
adamts13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr11_+_37201483 0.82 ENSDART00000160930
ENSDART00000173439
ENSDART00000171273
zgc:112265
zgc:112265
chr1_-_9249943 0.82 ENSDART00000055011
zgc:136472
zgc:136472
chr1_-_23157583 0.82 ENSDART00000144208
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr23_-_19434199 0.79 ENSDART00000132543
klhdc8b
kelch domain containing 8B
chr7_+_20535869 0.79 ENSDART00000078181
zgc:158423
zgc:158423
chr19_-_41991104 0.76 ENSDART00000087055
trioa
trio Rho guanine nucleotide exchange factor a
chr13_-_32648382 0.76 ENSDART00000138571
ENSDART00000132820
bend3
BEN domain containing 3
chr3_-_60142530 0.76 ENSDART00000153247
si:ch211-120g10.1
si:ch211-120g10.1
chr2_-_6262441 0.76 ENSDART00000092190
arl14
ADP-ribosylation factor-like 14
chr5_-_28102698 0.74 ENSDART00000138140
si:ch211-48m9.1
si:ch211-48m9.1
chr13_+_36144341 0.73 ENSDART00000182930
ENSDART00000187327
TTC9
si:ch211-259k16.3
chr1_+_37391716 0.73 ENSDART00000191986
sparcl1
SPARC-like 1
chr3_-_28665291 0.72 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr15_-_5467477 0.72 ENSDART00000123839
arrb1
arrestin, beta 1
chr3_+_39853788 0.72 ENSDART00000154869
cacna1ha
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr4_+_26628822 0.71 ENSDART00000191030
ENSDART00000186113
ENSDART00000186764
ENSDART00000165158
iqsec3a
IQ motif and Sec7 domain 3a
chr23_+_25832689 0.71 ENSDART00000138907
hnf4a
hepatocyte nuclear factor 4, alpha
chr4_-_5291256 0.71 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr3_-_22228602 0.70 ENSDART00000017750
myl4
myosin, light chain 4, alkali; atrial, embryonic
chr4_-_8902406 0.68 ENSDART00000192962
mpped1
metallophosphoesterase domain containing 1
chr21_-_7687544 0.68 ENSDART00000134519
pde8b
phosphodiesterase 8B
chr17_-_8169774 0.66 ENSDART00000091828
syne1b
spectrin repeat containing, nuclear envelope 1b
chr24_+_25692802 0.65 ENSDART00000190493
camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr17_+_43623598 0.63 ENSDART00000154138
znf365
zinc finger protein 365
chr13_-_40141630 0.62 ENSDART00000181618
ENSDART00000171583
ENSDART00000192780
crtac1b
cartilage acidic protein 1b
chr10_-_15405564 0.61 ENSDART00000020665
sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr7_+_25036188 0.60 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr18_-_46380471 0.60 ENSDART00000144444
ENSDART00000086772
slc19a3b
solute carrier family 19 (thiamine transporter), member 3b
chr2_-_17044959 0.60 ENSDART00000090260
clcn2a
chloride channel, voltage-sensitive 2a
chr21_+_4116437 0.59 ENSDART00000167791
ENSDART00000123759
rapgef1b
Rap guanine nucleotide exchange factor (GEF) 1b
chr5_-_67661102 0.59 ENSDART00000013605
zbtb20
zinc finger and BTB domain containing 20
chr15_-_34785594 0.58 ENSDART00000154256
gabbr1a
gamma-aminobutyric acid (GABA) B receptor, 1a
chr10_-_33156789 0.58 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cux1a
cut-like homeobox 1a
chr14_+_21699414 0.57 ENSDART00000169942
stx3a
syntaxin 3A
chr8_+_9866351 0.57 ENSDART00000133985
kcnd1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr8_+_23745167 0.57 ENSDART00000149352
si:ch211-163l21.11
si:ch211-163l21.11
chr25_+_19955598 0.56 ENSDART00000091547
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr5_+_19309877 0.53 ENSDART00000190338
rusc2
RUN and SH3 domain containing 2
chr5_-_63286077 0.53 ENSDART00000131274
tbcelb
tubulin folding cofactor E-like b
chr19_+_4916233 0.53 ENSDART00000159512
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr12_-_25217217 0.52 ENSDART00000152931
kcng3
potassium voltage-gated channel, subfamily G, member 3
chr18_+_36769758 0.52 ENSDART00000180375
ENSDART00000136463
ENSDART00000133487
ENSDART00000130206
fosb
FBJ murine osteosarcoma viral oncogene homolog B
chr22_-_7129631 0.50 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr14_-_41243180 0.49 ENSDART00000184548
drp2
dystrophin related protein 2
chr25_-_21085661 0.47 ENSDART00000099355
prr5a
proline rich 5a (renal)
chr21_-_28439596 0.46 ENSDART00000089980
ENSDART00000132844
rasgrp2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr23_-_3721444 0.46 ENSDART00000141682
nudt3a
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr15_-_31265375 0.46 ENSDART00000086592
vezf1b
vascular endothelial zinc finger 1b
chr4_-_9214288 0.46 ENSDART00000067309
avpr1ab
arginine vasopressin receptor 1Ab
chr12_+_26467847 0.45 ENSDART00000022495
ndel1a
nudE neurodevelopment protein 1-like 1a
chr15_+_17446796 0.43 ENSDART00000157189
snx19b
sorting nexin 19b
chr12_-_4475890 0.42 ENSDART00000092492
si:ch211-173d10.1
si:ch211-173d10.1
chr3_-_30434016 0.42 ENSDART00000150958
lrrc4ba
leucine rich repeat containing 4Ba
chr18_-_21806613 0.41 ENSDART00000145721
nrn1la
neuritin 1-like a
chr7_+_42206847 0.40 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr4_-_2868112 0.40 ENSDART00000133843
pde3a
phosphodiesterase 3A, cGMP-inhibited
chr7_-_68419830 0.39 ENSDART00000191606
CU468723.2

chr5_-_23675222 0.39 ENSDART00000135153
TBC1D8B
si:dkey-110k5.6
chr23_-_17470146 0.39 ENSDART00000002398
trim101
tripartite motif containing 101
chr21_-_22812417 0.38 ENSDART00000079151
ENSDART00000112175
trpc6a
transient receptor potential cation channel, subfamily C, member 6a
chr22_-_7669624 0.38 ENSDART00000189617
AL929276.2

chr3_-_8399774 0.38 ENSDART00000190238
ENSDART00000113140
ENSDART00000132949
rbfox3b
RNA binding fox-1 homolog 3b
chr7_-_71434298 0.36 ENSDART00000180507
lgi2a
leucine-rich repeat LGI family, member 2a
chr14_-_1313480 0.36 ENSDART00000097748
il21
interleukin 21
chr16_+_46492994 0.36 ENSDART00000134734
rpz5
rapunzel 5
chr20_+_22130284 0.35 ENSDART00000025575
clocka
clock circadian regulator a
chr23_-_15216654 0.34 ENSDART00000131649
sulf2b
sulfatase 2b
chr21_+_20229926 0.33 ENSDART00000025860
si:dkey-247m21.3
si:dkey-247m21.3
chr6_+_4255319 0.33 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr2_-_31735142 0.32 ENSDART00000130903
ralyl
RALY RNA binding protein like
chr2_+_42871831 0.32 ENSDART00000171393
efr3a
EFR3 homolog A (S. cerevisiae)
chr4_+_13810811 0.30 ENSDART00000067168
pdzrn4
PDZ domain containing ring finger 4
chr24_-_36680261 0.30 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr23_+_28770225 0.30 ENSDART00000132179
ENSDART00000142273
masp2
mannan-binding lectin serine peptidase 2
chr23_-_11128601 0.29 ENSDART00000131232
cntn3a.2
contactin 3a, tandem duplicate 2
chr18_+_36770166 0.28 ENSDART00000078151
fosb
FBJ murine osteosarcoma viral oncogene homolog B
chr20_-_6812688 0.28 ENSDART00000170934
igfbp1a
insulin-like growth factor binding protein 1a
chr15_+_11381532 0.28 ENSDART00000124172
si:ch73-321d9.2
si:ch73-321d9.2
chr20_+_52546186 0.26 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr11_-_426525 0.26 ENSDART00000157054
znf831
zinc finger protein 831
chr16_-_26255877 0.24 ENSDART00000146214
erfl1
Ets2 repressor factor like 1
chr24_+_2962988 0.24 ENSDART00000164449
eci2
enoyl-CoA delta isomerase 2
chr1_-_54191626 0.24 ENSDART00000062941
nthl1
nth-like DNA glycosylase 1
chr8_+_37168570 0.23 ENSDART00000098636
csf1b
colony stimulating factor 1b (macrophage)
chr11_+_43114108 0.22 ENSDART00000013642
ENSDART00000190266
foxg1b
forkhead box G1b
chr8_+_21280360 0.21 ENSDART00000144488
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr9_+_44430974 0.20 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr3_-_32071468 0.20 ENSDART00000121979
BX511080.1

chr21_+_3901775 0.18 ENSDART00000053609
dolpp1
dolichyldiphosphatase 1
chr16_-_16701718 0.18 ENSDART00000143550
si:dkey-8k3.2
si:dkey-8k3.2
chr25_+_32496877 0.18 ENSDART00000132698
ctdspl2a
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr17_+_8175998 0.17 ENSDART00000131200
myct1b
myc target 1b
chr6_-_49861506 0.17 ENSDART00000121809
gnas
GNAS complex locus
chr16_-_2650341 0.17 ENSDART00000128169
ENSDART00000155432
ENSDART00000103722
lyplal1
lysophospholipase-like 1
chr8_-_14484599 0.16 ENSDART00000057644
lhx4
LIM homeobox 4
chr5_+_42136359 0.16 ENSDART00000083731
trpv1
transient receptor potential cation channel, subfamily V, member 1
chr15_+_41901970 0.15 ENSDART00000152724
si:ch211-191a16.5
si:ch211-191a16.5
chr13_-_24877577 0.15 ENSDART00000182705
kat6b
K(lysine) acetyltransferase 6B
chr5_-_14211487 0.15 ENSDART00000135731
npffr1l2
neuropeptide FF receptor 1 like 2
chr6_-_16456093 0.15 ENSDART00000083305
ENSDART00000181640
slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr6_-_7052408 0.14 ENSDART00000150033
ENSDART00000149232
bin1b
bridging integrator 1b
chr19_-_17526735 0.14 ENSDART00000189391
thrb
thyroid hormone receptor beta
chr15_-_30984557 0.13 ENSDART00000080328
nf1a
neurofibromin 1a
chr8_-_621142 0.13 ENSDART00000187576
ENSDART00000190316
si:ch211-87m7.2
si:ch211-87m7.2
chr22_-_38360205 0.13 ENSDART00000162055
mark1
MAP/microtubule affinity-regulating kinase 1
chr2_+_5563077 0.11 ENSDART00000111220
mb21d2
Mab-21 domain containing 2
chr15_-_26552652 0.11 ENSDART00000152336
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr4_-_13255700 0.11 ENSDART00000162277
ENSDART00000026593
grip1
glutamate receptor interacting protein 1
chr4_-_31700186 0.11 ENSDART00000183986
ENSDART00000180890
si:dkey-16p6.1
si:dkey-16p6.1
chr18_+_8937718 0.10 ENSDART00000138115
si:dkey-5i3.1
si:dkey-5i3.1
chr23_+_19655301 0.09 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr8_-_4010887 0.09 ENSDART00000163678
mtmr3
myotubularin related protein 3
chr19_-_32641725 0.09 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr7_+_30933867 0.08 ENSDART00000156325
tjp1a
tight junction protein 1a
chr8_+_35664152 0.08 ENSDART00000144520
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr5_+_7393346 0.06 ENSDART00000164238
si:ch73-72b7.1
si:ch73-72b7.1
chr20_-_19422496 0.06 ENSDART00000143658
si:ch211-278j3.3
si:ch211-278j3.3
chr5_+_4366431 0.06 ENSDART00000168560
ENSDART00000149185
sat1a.2
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr19_+_19512515 0.04 ENSDART00000180065
jazf1a
JAZF zinc finger 1a
chr18_-_17030870 0.04 ENSDART00000079817
has3
hyaluronan synthase 3
chr23_-_20002459 0.03 ENSDART00000163396
b4galt3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr16_+_22587661 0.03 ENSDART00000129612
ENSDART00000142241
she
Src homology 2 domain containing E
chr5_-_69212184 0.02 ENSDART00000053963
mat2ab
methionine adenosyltransferase II, alpha b
chr10_-_7785930 0.02 ENSDART00000043961
ENSDART00000111058
mpx
myeloid-specific peroxidase
chr22_-_28653074 0.02 ENSDART00000154717
col8a1b
collagen, type VIII, alpha 1b
chr11_-_22303678 0.02 ENSDART00000159527
ENSDART00000159681
tfeb
transcription factor EB
chr15_-_39948635 0.02 ENSDART00000114836
msh5
mutS homolog 5
chr13_+_28417297 0.01 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr6_-_8498908 0.01 ENSDART00000149222
pglyrp2
peptidoglycan recognition protein 2
chr10_+_10801719 0.00 ENSDART00000193648
ambp
alpha-1-microglobulin/bikunin precursor
chr21_+_19525141 0.00 ENSDART00000058489
gzma
granzyme A

Network of associatons between targets according to the STRING database.

First level regulatory network of onecut2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.6 GO:1903646 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.2 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.2 2.0 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.2 0.7 GO:0060300 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.2 1.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.8 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 1.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 2.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.8 GO:0048899 anterior lateral line development(GO:0048899)
0.1 2.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.5 GO:1901907 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 1.4 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.9 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.1 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 2.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 2.2 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0046552 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.0 1.9 GO:0031103 axon regeneration(GO:0031103)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.7 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.5 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.8 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.7 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.8 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0045117 azole transport(GO:0045117)
0.0 0.1 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.3 GO:0009648 photoperiodism(GO:0009648)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0044316 cone cell pedicle(GO:0044316)
0.2 0.6 GO:0072380 TRC complex(GO:0072380)
0.1 2.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.6 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.3 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.0 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.8 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.2 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.4 GO:0005882 intermediate filament(GO:0005882)
0.0 2.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0030667 secretory granule membrane(GO:0030667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 2.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 1.4 GO:0032052 bile acid binding(GO:0032052)
0.2 0.6 GO:0030882 lipid antigen binding(GO:0030882)
0.2 1.0 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.6 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 2.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.2 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1 0.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 2.8 GO:0042562 hormone binding(GO:0042562)
0.0 1.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0050780 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 1.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.1 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis