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PRJEB1986: zebrafish developmental stages transcriptome

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Results for osr1

Z-value: 0.97

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Transcription factors associated with osr1

Gene Symbol Gene ID Gene Info
ENSDARG00000014091 odd-skipped related transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
osr1dr11_v1_chr13_+_32148338_32148338-0.311.9e-01Click!

Activity profile of osr1 motif

Sorted Z-values of osr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_8040436 3.87 ENSDART00000113033
si:ch211-240l19.6
chr11_-_29996344 3.65 ENSDART00000003712
ENSDART00000126110
angiotensin I converting enzyme 2
chr20_+_30490682 2.59 ENSDART00000184871
myelin transcription factor 1-like, a
chr18_+_907266 2.50 ENSDART00000171729
pyruvate kinase M1/2a
chr9_-_22069364 2.50 ENSDART00000101938
crystallin, gamma M2b
chr19_-_1023051 2.44 ENSDART00000158429
transmembrane protein 42b
chr14_+_35901249 2.40 ENSDART00000105604
zgc:77938
chr13_-_992458 2.35 ENSDART00000114655
beaded filament structural protein 1
chr20_-_29418620 2.18 ENSDART00000172634
ryanodine receptor 3
chr24_+_40529346 2.16 ENSDART00000168548

chr2_+_39021282 2.16 ENSDART00000056577
si:ch211-119o8.7
chr5_-_55981288 2.13 ENSDART00000146616
si:dkey-189h5.6
chr17_+_31185276 2.12 ENSDART00000062887
dispatched homolog 2 (Drosophila)
chr9_-_22023061 2.11 ENSDART00000101952
crystallin, gamma M2c
chr3_+_19460991 2.07 ENSDART00000169124
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog a
chr2_-_11512819 2.01 ENSDART00000142013
proenkephalin a
chr3_-_61181018 1.99 ENSDART00000187970
parvalbumin 4
chr5_+_30682737 1.98 ENSDART00000172886
PDZ domain containing 3b
chr3_-_30123113 1.88 ENSDART00000153562
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr23_-_30785382 1.88 ENSDART00000136156
ENSDART00000131285
myelin transcription factor 1a
chr1_-_21344478 1.87 ENSDART00000077805
glutamate receptor, ionotropic, AMPA 2a
chr10_+_2587234 1.84 ENSDART00000126937
wu:fb59d01
chr15_-_462783 1.77 ENSDART00000161049
Danio rerio uncharacterized LOC100002960 (LOC100002960), mRNA.
chr20_+_1412193 1.75 ENSDART00000064419
liver-enriched gene 1, tandem duplicate 1
chr15_-_576135 1.75 ENSDART00000124170
cerebellin 20
chr14_+_4151379 1.74 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr1_-_8928841 1.70 ENSDART00000103652
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr14_+_49135264 1.67 ENSDART00000084119
si:ch1073-44g3.1
chr8_-_53896982 1.63 ENSDART00000169206
mindbomb E3 ubiquitin protein ligase 2
chr11_-_37548711 1.62 ENSDART00000127184
bassoon (presynaptic cytomatrix protein) b
chr1_-_34750169 1.60 ENSDART00000149380
si:dkey-151m22.8
chr16_-_27749172 1.58 ENSDART00000145198
STEAP family member 4
chr10_-_2526526 1.57 ENSDART00000191726
ENSDART00000192767

chr12_+_31713239 1.55 ENSDART00000122379
hyaluronan binding protein 2
chr8_-_33114202 1.53 ENSDART00000098840
Ral GEF with PH domain and SH3 binding motif 1
chr4_-_67969695 1.50 ENSDART00000190016
si:ch211-223k15.1
chr19_-_9503473 1.50 ENSDART00000091615
intermediate filament family orphan 1a
chr15_+_3219134 1.48 ENSDART00000113532

chr13_-_33022372 1.46 ENSDART00000147165
RNA binding motif protein 25a
chr25_-_19395476 1.44 ENSDART00000182622
microtubule-associated protein 1Ab
chr21_+_10021823 1.43 ENSDART00000163995
hect domain and RLD 7
chr3_+_23248542 1.38 ENSDART00000185765
ENSDART00000192332
protein phosphatase 1, regulatory subunit 9Ba
chr2_+_20539402 1.37 ENSDART00000129585
si:ch73-14h1.2
chr22_-_28871787 1.34 ENSDART00000104828
GTP binding protein 2b
chr1_+_44826593 1.34 ENSDART00000162200
zgc:165520
chr7_+_29954709 1.34 ENSDART00000173904
alpha-tropomyosin
chr2_+_50626476 1.33 ENSDART00000018150
neuronal differentiation 6b
chr2_+_3986083 1.32 ENSDART00000188979
mohawk homeobox b
chr20_-_5291012 1.31 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr13_-_40499296 1.27 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr2_-_9646857 1.26 ENSDART00000056901
zgc:153615
chr13_-_11536951 1.25 ENSDART00000018155
adenylosuccinate synthase
chr23_+_43809484 1.24 ENSDART00000149534
si:ch211-149b19.3
chr1_-_58064738 1.23 ENSDART00000073778
caspase b
chr12_-_45533034 1.18 ENSDART00000113004

chr1_+_10771457 1.18 ENSDART00000027050
ENSDART00000137185
cyclic nucleotide gated channel alpha 3b
chr18_-_43880020 1.17 ENSDART00000185638
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr10_-_19497914 1.17 ENSDART00000132084
si:ch211-127i16.2
chr17_-_26537928 1.15 ENSDART00000155692
ENSDART00000122366
coiled-coil serine-rich protein 2a
chr13_-_3351708 1.12 ENSDART00000042875
si:ch73-193i2.2
chr10_+_21559605 1.12 ENSDART00000123648
ENSDART00000108584
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr18_+_1703984 1.11 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr8_-_22639794 1.10 ENSDART00000188029
IQ motif and Sec7 domain 2a
chr25_+_35212919 1.09 ENSDART00000180127
anoctamin 5a
chr20_+_43113465 1.08 ENSDART00000004842
dual specificity phosphatase 23a
chr22_-_11626014 1.08 ENSDART00000063133
ENSDART00000160085
glucagon a
chr12_-_7824291 1.08 ENSDART00000148673
ENSDART00000149453
ankyrin 3b
chr5_-_43682930 1.07 ENSDART00000075017
si:dkey-40c11.1
chr4_+_3287819 1.07 ENSDART00000168633

chr21_-_40083432 1.05 ENSDART00000141160
ENSDART00000191195
info solute carrier family 13 (sodium-dependent citrate transporter), member 5a
chr18_+_21408794 1.05 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr13_+_30696286 1.04 ENSDART00000192411
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr2_+_37897079 1.04 ENSDART00000141784
telomerase-associated protein 1
chr17_-_22021213 1.02 ENSDART00000078843
zmp:0000001102
chr7_-_4036875 1.02 ENSDART00000165021
NDRG family member 2
chr15_-_12011202 1.02 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
chr14_+_33955807 1.01 ENSDART00000173316
si:ch73-22o18.1
chr7_-_11605185 1.01 ENSDART00000169291
ENSDART00000113904
StAR-related lipid transfer (START) domain containing 5
chr15_+_22390076 0.99 ENSDART00000183764
OAF homolog a (Drosophila)
chr21_-_13662237 0.98 ENSDART00000091647
ENSDART00000151547
patatin-like phospholipase domain containing 7a
chr20_+_46560258 0.97 ENSDART00000122115
si:ch211-153j24.3
chr22_-_19102256 0.97 ENSDART00000171866
ENSDART00000166295
polymerase (RNA) mitochondrial (DNA directed)
chr10_+_29137482 0.96 ENSDART00000178280
phosphatidylinositol binding clathrin assembly protein a
chr7_-_71758613 0.95 ENSDART00000166724
myomesin 1b
chr21_+_21195487 0.94 ENSDART00000181746
ENSDART00000184832
RPTOR independent companion of MTOR, complex 2b
chr11_+_21053488 0.93 ENSDART00000189860
zgc:113307
chr2_+_35421285 0.93 ENSDART00000143787
tenascin R (restrictin, janusin)
chr7_+_29955368 0.93 ENSDART00000173686
alpha-tropomyosin
chr3_-_4303262 0.92 ENSDART00000112819
si:dkey-73p2.2
chr11_+_25735478 0.92 ENSDART00000103566
si:dkey-183j2.10
chr2_-_57076687 0.91 ENSDART00000161523
solute carrier family 25, member 42
chr10_-_13239367 0.91 ENSDART00000001253
si:busm1-57f23.1
chr19_-_6134802 0.91 ENSDART00000140051
capicua transcriptional repressor a
chr1_-_52201266 0.91 ENSDART00000143805
ENSDART00000023757
RAB3D, member RAS oncogene family, a
chr14_-_33872092 0.91 ENSDART00000111903
si:ch73-335m24.2
chr16_+_35344031 0.90 ENSDART00000167140
si:dkey-34d22.1
chr3_-_26115558 0.89 ENSDART00000078671
ENSDART00000124762
heat shock cognate 70-kd protein, tandem duplicate 1
chr3_+_17744339 0.89 ENSDART00000132622
zinc finger protein 385C
chr9_-_18568927 0.87 ENSDART00000084668
ecto-NOX disulfide-thiol exchanger 1
chr5_-_16996482 0.86 ENSDART00000144501
polypeptide N-acetylgalactosaminyltransferase 9
chr10_-_5814101 0.85 ENSDART00000161903
interleukin 6 signal transducer
chr8_+_49778756 0.85 ENSDART00000083790
neurotrophic tyrosine kinase, receptor, type 2a
chr9_-_39547907 0.83 ENSDART00000163635
erb-b2 receptor tyrosine kinase 4b
chr19_+_14921000 0.83 ENSDART00000144052
opioid receptor, delta 1a
chr20_-_26866111 0.83 ENSDART00000077767
myosin light chain kinase family, member 4b
chr14_-_2203124 0.83 ENSDART00000124171
si:dkeyp-115d7.2
chr25_+_7670683 0.82 ENSDART00000040275
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr5_-_16274058 0.82 ENSDART00000090684
kringle containing transmembrane protein 1
chr20_+_53522059 0.82 ENSDART00000147570
p21 protein (Cdc42/Rac)-activated kinase 6b
chr1_-_7912932 0.81 ENSDART00000147383
monocyte to macrophage differentiation-associated 2b
chr25_-_19395156 0.81 ENSDART00000155335
microtubule-associated protein 1Ab
chr13_+_25396896 0.80 ENSDART00000041257
glutathione S-transferase omega 2
chr9_-_5263947 0.80 ENSDART00000088342
cytohesin 1 interacting protein
chr9_-_34269066 0.79 ENSDART00000059955
immunoglobulin-like domain containing receptor 1b
chr16_-_26537103 0.79 ENSDART00000134908
ENSDART00000008152
serum/glucocorticoid regulated kinase 2b
chr7_-_42206720 0.79 ENSDART00000110907
integrin alpha FG-GAP repeat containing 1
chr9_-_4856767 0.79 ENSDART00000016814
ENSDART00000138015
formin-like 2a
chr11_-_33960318 0.78 ENSDART00000087597
collagen, type VI, alpha 2
chr3_+_61896514 0.77 ENSDART00000113524
ENSDART00000158997
family with sequence similarity 20, member Ca
chr1_+_9886991 0.77 ENSDART00000135702
regulator of G protein signaling 11
chr25_+_37435720 0.76 ENSDART00000164390
charged multivesicular body protein 1A
chr19_-_35361556 0.76 ENSDART00000012167
NADH dehydrogenase (ubiquinone) Fe-S protein 5
chr7_+_20656942 0.74 ENSDART00000100898
TNF superfamily member 12
chr7_+_22767678 0.73 ENSDART00000137203
plac8 onzin related protein 6
chr8_-_4100365 0.73 ENSDART00000142846
cut-like homeobox 2b
chr7_-_17771166 0.72 ENSDART00000173620
si:dkey-106g10.7
chr23_-_42752550 0.71 ENSDART00000187059
si:ch73-217n20.1
chr2_-_15318786 0.71 ENSDART00000135851
trans-2,3-enoyl-CoA reductase-like 2b
chr10_-_25860102 0.71 ENSDART00000080789
transient receptor potential cation channel, subfamily C, member 4a
chr6_+_52947186 0.71 ENSDART00000155831
ubiquitin-like modifier activating enzyme 7
chr21_-_37951819 0.71 ENSDART00000139549
si:dkey-38k9.5
chr13_+_25397098 0.70 ENSDART00000132953
glutathione S-transferase omega 2
chr13_+_50151407 0.70 ENSDART00000031858
G protein-coupled receptor 137Ba
chr13_-_27038407 0.69 ENSDART00000146712
coiled-coil domain containing 85A
chr7_-_57949117 0.69 ENSDART00000138803
ankyrin 2b, neuronal
chr19_-_25519310 0.69 ENSDART00000089882
si:dkey-202e17.1
chr19_+_10794072 0.68 ENSDART00000151518
ENSDART00000142614
lipase, hormone-sensitive a
chr13_+_23132666 0.68 ENSDART00000164639
sorbin and SH3 domain containing 1
chr10_+_29138021 0.68 ENSDART00000025227
ENSDART00000123033
ENSDART00000034242
phosphatidylinositol binding clathrin assembly protein a
chr12_-_15620090 0.67 ENSDART00000038032
acyl-CoA binding domain containing 4
chr4_-_6567355 0.67 ENSDART00000134820
ENSDART00000142087
forkhead box P2
chr15_-_25392589 0.66 ENSDART00000124205
si:dkey-54n8.4
chr19_-_5769553 0.66 ENSDART00000175003
si:ch211-264f5.6
chr2_-_14387335 0.66 ENSDART00000189332
ENSDART00000164786
ENSDART00000188572
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr25_+_34581494 0.65 ENSDART00000167690
transient receptor potential cation channel, subfamily M, member 1b
chr20_+_16881883 0.63 ENSDART00000130107
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr24_-_9960290 0.63 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr21_+_39365920 0.63 ENSDART00000140940
clustered mitochondria (cluA/CLU1) homolog b
chr2_-_9748039 0.62 ENSDART00000134870
si:ch1073-170o4.1
chr3_-_10751491 0.62 ENSDART00000016351
zgc:112965
chr5_+_69747417 0.62 ENSDART00000153717
si:ch211-275j6.5
chr5_+_69808763 0.62 ENSDART00000143482
fibronectin type III and SPRY domain containing 1-like
chr15_-_1843831 0.62 ENSDART00000156718
ENSDART00000154175
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr15_-_5016039 0.61 ENSDART00000156458
defensin, beta-like 3
chr8_+_3496204 0.61 ENSDART00000085993
paxillin b
chr17_-_23631400 0.61 ENSDART00000079563
Fas cell surface death receptor
chr2_-_49557932 0.61 ENSDART00000141902
si:ch211-209f23.3
chr22_+_26804197 0.60 ENSDART00000135688
si:dkey-44g23.2
chr10_+_19554604 0.59 ENSDART00000063806
ATPase H+ transporting V1 subunit B2
chr8_+_30709685 0.59 ENSDART00000133989
ureidopropionase, beta
chr1_+_44800298 0.58 ENSDART00000073712
ENSDART00000187054
transmembrane protein 187
chr23_-_42752387 0.57 ENSDART00000149781
si:ch73-217n20.1
chr15_-_4415917 0.57 ENSDART00000062874
ATPase Na+/K+ transporting subunit beta 3b
chr7_+_28006096 0.57 ENSDART00000173843
tubby bipartite transcription factor
chr15_-_38154616 0.56 ENSDART00000099392
immunity-related GTPase family, q2
chr8_-_36469117 0.56 ENSDART00000111240
major histocompatibility complex class II DAB gene
chr2_+_49799470 0.55 ENSDART00000146325
si:ch211-190k17.19
chr14_+_17137023 0.55 ENSDART00000080712
solute carrier family 43, member 3b
chr15_-_434503 0.55 ENSDART00000122286

chr2_-_51096647 0.54 ENSDART00000167172
si:ch73-52e5.2
chr5_-_5831037 0.54 ENSDART00000112856
zmp:0000000846
chr11_-_41130239 0.53 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr3_-_29899172 0.53 ENSDART00000140518
ENSDART00000020311
ribosomal protein L27
chr2_+_1001560 0.53 ENSDART00000134656
calcium channel, voltage-dependent, R type, alpha 1E subunit b
chr13_+_12456412 0.52 ENSDART00000057762
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr21_+_45627775 0.52 ENSDART00000185466
interferon regulatory factor 1b
chr5_+_6617401 0.52 ENSDART00000060532
zgc:110796
chr3_-_30384353 0.50 ENSDART00000186832
leucine rich repeat containing 4Ba
chr6_-_41229787 0.50 ENSDART00000065013
synaptoporin
chr3_+_32129632 0.50 ENSDART00000174522
zgc:109934
chr5_+_25317061 0.49 ENSDART00000170097
transient receptor potential cation channel, subfamily M, member 6
chr6_-_48087152 0.48 ENSDART00000180614
solute carrier family 2 (facilitated glucose transporter), member 1b
chr3_+_23063718 0.48 ENSDART00000140225
ENSDART00000184431
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 1
chr7_+_42206847 0.48 ENSDART00000149250
phosphorylase kinase, beta
chr7_+_38090515 0.47 ENSDART00000131387
CCAAT/enhancer binding protein (C/EBP), gamma
chr17_+_10094063 0.47 ENSDART00000168055
Sec23 homolog A, COPII coat complex component
chr23_+_38953545 0.47 ENSDART00000184621
ATPase phospholipid transporting 9A (putative)
chr18_-_16395668 0.47 ENSDART00000186004
mgat4 family, member C
chr6_+_52947699 0.46 ENSDART00000180913
ubiquitin-like modifier activating enzyme 7
chr12_+_2993523 0.45 ENSDART00000082297
leucine rich repeat containing 45
chr4_-_13156971 0.45 ENSDART00000182164
glutamate receptor interacting protein 1
chr10_+_10677697 0.45 ENSDART00000188705
family with sequence similarity 163, member B
chr14_-_24391424 0.44 ENSDART00000113376
ENSDART00000126894
family with sequence similarity 13, member B
chr10_+_33744098 0.44 ENSDART00000147775
relaxin/insulin-like family peptide receptor 2a
chr14_-_1538600 0.44 ENSDART00000180925

chr3_+_54776475 0.43 ENSDART00000142710
si:ch211-74m13.1
chr7_-_55292116 0.43 ENSDART00000122603
ring finger protein 166
chr21_-_28737320 0.43 ENSDART00000098696
ENSDART00000124826
ENSDART00000125652
neuregulin 2a
chr21_-_40834413 0.42 ENSDART00000148513
LIM domain kinase 1b
chr24_+_16393302 0.42 ENSDART00000188670
ENSDART00000081759
ENSDART00000177790
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

Network of associatons between targets according to the STRING database.

First level regulatory network of osr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0015677 copper ion import(GO:0015677)
0.3 2.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.3 2.4 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.3 0.8 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 0.7 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.2 0.6 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.2 1.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 0.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 0.8 GO:0070166 enamel mineralization(GO:0070166)
0.2 1.7 GO:1990402 embryonic liver development(GO:1990402)
0.2 0.9 GO:0007624 ultradian rhythm(GO:0007624)
0.2 1.7 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 2.7 GO:0048899 anterior lateral line development(GO:0048899)
0.2 1.6 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 1.1 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.2 0.6 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.1 1.0 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 1.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.9 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 1.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.6 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 0.4 GO:0016038 absorption of visible light(GO:0016038)
0.1 0.4 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 1.7 GO:0042574 retinal metabolic process(GO:0042574)
0.1 1.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 2.2 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 0.6 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 0.9 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 2.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0006210 thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 2.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.2 GO:0046686 response to cadmium ion(GO:0046686)
0.1 0.4 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.1 3.6 GO:0060402 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.1 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.5 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 2.0 GO:0035195 gene silencing by miRNA(GO:0035195)
0.0 0.7 GO:0045471 response to ethanol(GO:0045471)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 2.4 GO:0006096 glycolytic process(GO:0006096)
0.0 0.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 4.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.4 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.6 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.6 GO:0006415 translational termination(GO:0006415)
0.0 0.8 GO:0019835 cytolysis(GO:0019835)
0.0 0.9 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.2 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.2 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 1.1 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.0 0.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.8 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 1.3 GO:0006414 translational elongation(GO:0006414)
0.0 0.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.6 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 1.6 GO:0061515 myeloid cell development(GO:0061515)
0.0 1.9 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 1.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.2 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 1.7 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.5 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.8 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.6 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.9 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 1.2 GO:0061702 inflammasome complex(GO:0061702)
0.3 2.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 0.9 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.5 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.2 1.6 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 1.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.6 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.6 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 0.6 GO:0030897 HOPS complex(GO:0030897)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.6 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.0 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 0.9 GO:0031430 M band(GO:0031430)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 1.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 2.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.7 GO:0005884 actin filament(GO:0005884)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.6 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.5 1.5 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.5 2.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.4 2.2 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.4 1.7 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.4 2.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 0.9 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 0.8 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.3 0.8 GO:0038046 enkephalin receptor activity(GO:0038046)
0.2 0.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.3 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.2 1.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.2 1.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.0 GO:0032052 bile acid binding(GO:0032052)
0.2 1.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 2.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 2.0 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 1.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 3.6 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 1.2 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.6 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.7 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 4.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.0 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.1 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.1 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 2.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 1.1 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.4 REACTOME OPSINS Genes involved in Opsins
0.1 1.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation