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PRJEB1986: zebrafish developmental stages transcriptome

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Results for otpa+otpb

Z-value: 0.47

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Transcription factors associated with otpa+otpb

Gene Symbol Gene ID Gene Info
otpa
ENSDARG00000014201 orthopedia homeobox a
otpb
ENSDARG00000058379 orthopedia homeobox b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otpadr11_v1_chr21_+_7582036_7582059-0.321.8e-01Click!
otpbdr11_v1_chr5_-_51619262_516193210.106.9e-01Click!

Activity profile of otpa+otpb motif

Sorted Z-values of otpa+otpb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_54209504 1.74 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr12_-_35830625 1.56 ENSDART00000180028
CU459056.1

chr1_-_31534089 1.50 ENSDART00000007770
lbx1b
ladybird homeobox 1b
chr17_-_16422654 1.48 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr20_+_98179 1.11 ENSDART00000022725
si:ch1073-155h21.1
si:ch1073-155h21.1
chr23_+_36460239 1.04 ENSDART00000172441
lima1a
LIM domain and actin binding 1a
chr3_-_15999501 0.99 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr3_-_19368435 0.95 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr7_+_38811800 0.93 ENSDART00000052322
zgc:110699
zgc:110699
chr24_+_19415124 0.92 ENSDART00000186931
sulf1
sulfatase 1
chr3_+_6469754 0.85 ENSDART00000185809
NUP85 (1 of many)
nucleoporin 85
chr9_+_37152564 0.82 ENSDART00000189497
gli2a
GLI family zinc finger 2a
chr4_+_57881965 0.81 ENSDART00000162234
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr25_+_22320738 0.79 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr20_+_11731039 0.78 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr23_-_16485190 0.78 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr1_+_21731382 0.74 ENSDART00000054395
pax5
paired box 5
chr22_-_16154771 0.74 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr7_-_30174882 0.72 ENSDART00000110409
frmd5
FERM domain containing 5
chr11_-_10456553 0.72 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
ect2
epithelial cell transforming 2
chr1_-_45616470 0.72 ENSDART00000150165
atf7ip
activating transcription factor 7 interacting protein
chr5_+_67390115 0.72 ENSDART00000193255
ebf2
early B cell factor 2
chr9_-_27398369 0.72 ENSDART00000186499
tex30
testis expressed 30
chr14_+_989733 0.70 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
si:ch73-308l14.2
chr9_+_48761455 0.70 ENSDART00000139631
abcb11a
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr25_-_21031007 0.68 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr11_+_44617021 0.68 ENSDART00000158887
rbm34
RNA binding motif protein 34
chr22_+_508290 0.66 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr11_-_10456387 0.65 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr5_+_60590796 0.65 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr22_-_14247276 0.64 ENSDART00000033332
si:ch211-246m6.5
si:ch211-246m6.5
chr6_-_33878665 0.63 ENSDART00000129916
tmem69
transmembrane protein 69
chr1_+_52792439 0.62 ENSDART00000123972
smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr11_+_34760628 0.62 ENSDART00000087216
si:dkey-202e22.2
si:dkey-202e22.2
chr23_+_1029450 0.61 ENSDART00000189196
si:zfos-905g2.1
si:zfos-905g2.1
chr2_-_30668580 0.60 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr18_+_14619544 0.60 ENSDART00000010821
utp4
UTP4, small subunit processome component
chr21_+_25236297 0.59 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr14_-_26425416 0.59 ENSDART00000088690
lman2
lectin, mannose-binding 2
chr1_-_669717 0.57 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr19_+_43359075 0.55 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr5_+_41477954 0.54 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr18_+_17725410 0.53 ENSDART00000090608
rspry1
ring finger and SPRY domain containing 1
chr25_+_2263857 0.52 ENSDART00000076439
yars2
tyrosyl-tRNA synthetase 2, mitochondrial
chr24_+_28953089 0.51 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr8_-_33381913 0.51 ENSDART00000076420
lmx1bb
LIM homeobox transcription factor 1, beta b
chr25_-_27722614 0.50 ENSDART00000190154
zgc:153935
zgc:153935
chr6_-_35046735 0.50 ENSDART00000143649
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr23_-_16484383 0.49 ENSDART00000187839
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr18_+_41527877 0.48 ENSDART00000146972
selenot1b
selenoprotein T, 1b
chr5_+_41477526 0.48 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr3_+_13848226 0.47 ENSDART00000184342
ilf3b
interleukin enhancer binding factor 3b
chr8_+_49065348 0.47 ENSDART00000032277
ddx51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr22_-_36530902 0.47 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr20_-_45812144 0.47 ENSDART00000147897
ENSDART00000147637
fermt1
fermitin family member 1
chr20_+_25586099 0.45 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr3_+_26342768 0.45 ENSDART00000163832
si:ch211-156b7.4
si:ch211-156b7.4
chr8_-_33381430 0.45 ENSDART00000190019
lmx1bb
LIM homeobox transcription factor 1, beta b
chr1_+_45663727 0.44 ENSDART00000038574
ENSDART00000141144
ENSDART00000149565
trappc5
trafficking protein particle complex 5
chr14_-_1355544 0.44 ENSDART00000060417
cetn4
centrin 4
chr17_+_41992054 0.42 ENSDART00000182878
ENSDART00000111537
kiz
kizuna centrosomal protein
chr24_-_10006158 0.42 ENSDART00000106244
zgc:171750
zgc:171750
chr17_+_24821627 0.41 ENSDART00000112389
wdr43
WD repeat domain 43
chr22_-_10156581 0.40 ENSDART00000168304
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr9_+_23895711 0.40 ENSDART00000034686
cops8
COP9 signalosome subunit 8
chr5_-_12272689 0.39 ENSDART00000099810
nos1
nitric oxide synthase 1 (neuronal)
chr18_+_18439332 0.38 ENSDART00000043843
siah1
siah E3 ubiquitin protein ligase 1
chr10_-_11353469 0.38 ENSDART00000191847
lin54
lin-54 DREAM MuvB core complex component
chr25_-_28674739 0.37 ENSDART00000067073
lrrc10
leucine rich repeat containing 10
chr23_+_11285662 0.37 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr7_-_34448076 0.37 ENSDART00000170935
nr1h3
nuclear receptor subfamily 1, group H, member 3
chr6_+_25257728 0.36 ENSDART00000162581
kyat3
kynurenine aminotransferase 3
chr11_+_17984354 0.36 ENSDART00000179986
rpusd4
RNA pseudouridylate synthase domain containing 4
chr21_+_27513859 0.36 ENSDART00000065420
pacs1a
phosphofurin acidic cluster sorting protein 1a
chr4_+_13449775 0.35 ENSDART00000172552
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr16_+_25068576 0.35 ENSDART00000125838
im:7147486
im:7147486
chr10_+_1681518 0.35 ENSDART00000018532
triap1
TP53 regulated inhibitor of apoptosis 1
chr17_+_22577472 0.34 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr6_+_12527725 0.33 ENSDART00000149328
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr6_+_25261297 0.33 ENSDART00000162824
ENSDART00000163490
ENSDART00000157790
ENSDART00000160978
ENSDART00000161545
ENSDART00000159978
kyat3
kynurenine aminotransferase 3
chr12_+_20587179 0.33 ENSDART00000170127
arsg
arylsulfatase G
chr1_+_47499888 0.33 ENSDART00000027624
stn1
STN1, CST complex subunit
chr14_+_44794936 0.32 ENSDART00000128881
zgc:195212
zgc:195212
chr11_-_1509773 0.31 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr7_+_21272833 0.31 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr17_-_21418340 0.30 ENSDART00000007021
atp6v1ba
ATPase, H+ transporting, lysosomal, V1 subunit B, member a
chr18_-_17529763 0.30 ENSDART00000191308
bbs2
Bardet-Biedl syndrome 2
chr3_+_3681116 0.30 ENSDART00000109618
art4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr6_-_40029423 0.30 ENSDART00000103230
pfkfb4b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr16_+_28994709 0.30 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr19_+_2631565 0.29 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr3_+_26288981 0.29 ENSDART00000163500
rhot1a
ras homolog family member T1a
chr13_-_12602920 0.29 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr17_-_4245902 0.29 ENSDART00000151851
gdf3
growth differentiation factor 3
chr2_-_17393216 0.28 ENSDART00000123137
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr7_+_51774502 0.27 ENSDART00000007767
got2b
glutamic-oxaloacetic transaminase 2b, mitochondrial
chr20_-_9095105 0.27 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr1_-_51038885 0.27 ENSDART00000035150
spast
spastin
chr22_-_9183944 0.26 ENSDART00000188599
si:ch211-213a13.5
si:ch211-213a13.5
chr24_+_23202545 0.26 ENSDART00000143862
pex2
peroxisomal biogenesis factor 2
chr4_-_133492 0.25 ENSDART00000171845
gpr19
G protein-coupled receptor 19
chr21_-_1644414 0.24 ENSDART00000105736
ENSDART00000124904
zgc:152948
zgc:152948
chr14_+_1170968 0.23 ENSDART00000125203
ENSDART00000193575
hopx
HOP homeobox
chr23_+_12406722 0.23 ENSDART00000145008
pigt
phosphatidylinositol glycan anchor biosynthesis, class T
chr11_+_17984167 0.22 ENSDART00000020283
ENSDART00000188329
rpusd4
RNA pseudouridylate synthase domain containing 4
chr6_+_14980761 0.22 ENSDART00000087782
mrps9
mitochondrial ribosomal protein S9
chr16_+_23303859 0.22 ENSDART00000006093
slc50a1
solute carrier family 50 (sugar efflux transporter), member 1
chr14_-_470505 0.22 ENSDART00000067147
ANKRD50
ankyrin repeat domain 50
chr4_+_19700308 0.21 ENSDART00000027919
pax4
paired box 4
chr12_-_31794908 0.21 ENSDART00000105583
ENSDART00000153449
nat9
N-acetyltransferase 9 (GCN5-related, putative)
chr8_-_13046089 0.20 ENSDART00000137784
si:dkey-208b23.5
si:dkey-208b23.5
chr5_-_11809710 0.19 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr22_+_5532003 0.18 ENSDART00000106174
si:ch73-256j6.2
si:ch73-256j6.2
chr9_-_32177117 0.18 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr14_-_1200854 0.18 ENSDART00000106672
arl9
ADP-ribosylation factor-like 9
chr18_+_7456597 0.18 ENSDART00000142270
terb1
telomere repeat binding bouquet formation protein 1
chr2_-_17392799 0.17 ENSDART00000136470
ENSDART00000141188
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr22_+_2751887 0.16 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr18_+_33272861 0.15 ENSDART00000131796
v2ra20
vomeronasal 2 receptor, a20
chr17_-_25831569 0.15 ENSDART00000148743
hhat
hedgehog acyltransferase
chr14_-_33481428 0.15 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr17_+_20589553 0.15 ENSDART00000154447
si:ch73-288o11.4
si:ch73-288o11.4
chr5_+_33498253 0.14 ENSDART00000140993
ms4a17c.2
membrane-spanning 4-domains, subfamily A, member 17c.2
chr4_-_67980261 0.12 ENSDART00000182305
si:ch211-223k15.1
si:ch211-223k15.1
chr5_-_38451082 0.12 ENSDART00000136428
chrne
cholinergic receptor, nicotinic, epsilon
chr12_+_36428052 0.12 ENSDART00000131300
unk
unkempt family zinc finger
chr9_-_3934963 0.11 ENSDART00000062336
ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr25_+_21833287 0.11 ENSDART00000187606
ckmt1
creatine kinase, mitochondrial 1
chr16_+_23796612 0.11 ENSDART00000131698
rab13
RAB13, member RAS oncogene family
chr25_-_13490744 0.11 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr15_+_37965953 0.10 ENSDART00000154192
si:dkey-238d18.10
si:dkey-238d18.10
chr9_-_25055722 0.10 ENSDART00000137131
dnah7
dynein, axonemal, heavy chain 7
chr8_-_53044300 0.09 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr15_-_21014270 0.09 ENSDART00000154019
si:ch211-212c13.10
si:ch211-212c13.10
chr24_-_16980337 0.09 ENSDART00000183812
klhl15
kelch-like family member 15
chr4_-_9891874 0.09 ENSDART00000067193
adm2a
adrenomedullin 2a
chr4_+_59845617 0.09 ENSDART00000167626
ENSDART00000123157
si:dkey-196n19.2
si:dkey-196n19.2
chr1_+_51039558 0.08 ENSDART00000024743
dpy30
dpy-30 histone methyltransferase complex regulatory subunit
chr7_+_20512419 0.08 ENSDART00000173907
si:dkey-19b23.14
si:dkey-19b23.14
chr2_-_37140423 0.08 ENSDART00000144220
tspan37
tetraspanin 37
chr7_-_57509447 0.08 ENSDART00000051973
ENSDART00000147036
sirt3
sirtuin 3
chr20_-_29864390 0.08 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr9_+_24065855 0.06 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr2_+_37140448 0.06 ENSDART00000045016
ENSDART00000142940
pex19
peroxisomal biogenesis factor 19
chr18_+_7456888 0.06 ENSDART00000081468
terb1
telomere repeat binding bouquet formation protein 1
chr3_+_23029484 0.06 ENSDART00000187900
nags
N-acetylglutamate synthase
chr22_-_19552796 0.04 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
si:dkey-78l4.14
chr19_+_46158078 0.04 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr15_+_5360407 0.04 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr6_-_51771634 0.02 ENSDART00000073847
blcap
bladder cancer associated protein
chr21_+_38634296 0.02 ENSDART00000114467
AL935199.1

chr20_+_23408970 0.01 ENSDART00000144261
fryl
furry homolog, like
chr18_-_17485419 0.00 ENSDART00000018764
foxl1
forkhead box L1

Network of associatons between targets according to the STRING database.

First level regulatory network of otpa+otpb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0000012 single strand break repair(GO:0000012)
0.2 0.8 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.2 0.7 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.2 0.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.4 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.1 0.4 GO:1904729 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1 0.9 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 1.4 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.6 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.3 GO:0051228 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.7 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.2 GO:0045141 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 1.0 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.4 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.3 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.6 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 1.0 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.3 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.7 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 1.0 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.4 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.3 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.7 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.6 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.6 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0016233 telomere capping(GO:0016233)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.3 GO:1990879 CST complex(GO:1990879)
0.1 0.6 GO:0016589 NURF complex(GO:0016589)
0.1 0.2 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3 0.8 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 0.7 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 1.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.5 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 1.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 1.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 1.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.5 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.5 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling