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PRJEB1986: zebrafish developmental stages transcriptome

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Results for otx2b

Z-value: 2.20

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Transcription factors associated with otx2b

Gene Symbol Gene ID Gene Info
otx2b
ENSDARG00000011235 orthodenticle homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx2bdr11_v1_chr17_-_44249538_44249538-0.223.6e-01Click!

Activity profile of otx2b motif

Sorted Z-values of otx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_54077740 14.29 ENSDART00000027000
rho
rhodopsin
chr8_+_6954984 12.50 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr9_+_13714379 9.30 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr17_-_51202339 8.90 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr14_+_32839535 8.49 ENSDART00000168975
arr3b
arrestin 3b, retinal (X-arrestin)
chr3_+_34220194 7.59 ENSDART00000145859
slc25a23b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23b
chr3_+_15296824 7.35 ENSDART00000043801
cabp5b
calcium binding protein 5b
chr1_-_58009216 7.27 ENSDART00000143829
nxnl1
nucleoredoxin like 1
chr10_+_375042 6.74 ENSDART00000171854
si:ch1073-303d10.1
si:ch1073-303d10.1
chr23_+_39854566 6.45 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
si:ch73-217b7.1
chr17_-_12389259 6.22 ENSDART00000185724
snap25b
synaptosomal-associated protein, 25b
chr7_-_13882988 5.87 ENSDART00000169828
rlbp1a
retinaldehyde binding protein 1a
chr2_-_4797512 5.66 ENSDART00000160765
tnk2b
tyrosine kinase, non-receptor, 2b
chr2_+_7192966 5.66 ENSDART00000142735
si:ch211-13f8.1
si:ch211-13f8.1
chr11_-_15090564 5.45 ENSDART00000162079
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr14_+_40874608 5.40 ENSDART00000168448
si:ch211-106m9.1
si:ch211-106m9.1
chr7_+_19903924 5.38 ENSDART00000159112
si:ch211-285j22.3
si:ch211-285j22.3
chr6_-_28980756 5.30 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr16_-_17188294 5.17 ENSDART00000165883
opn9
opsin 9
chr25_-_17552299 5.08 ENSDART00000154327
si:dkey-44k1.5
si:dkey-44k1.5
chr16_+_32059785 5.02 ENSDART00000134459
si:dkey-40m6.8
si:dkey-40m6.8
chr21_+_10739846 5.02 ENSDART00000084011
cplx4a
complexin 4a
chr21_-_40782393 4.90 ENSDART00000075808
apbb3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr23_-_6641223 4.88 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr14_+_46313135 4.86 ENSDART00000172902
cryba1l1
crystallin, beta A1, like 1
chr3_+_26144765 4.86 ENSDART00000146267
ENSDART00000043932
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr11_-_15090118 4.85 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr7_+_19904136 4.67 ENSDART00000173452
si:ch211-285j22.3
si:ch211-285j22.3
chr14_-_2933185 4.58 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr2_+_37110504 4.54 ENSDART00000132794
ENSDART00000042974
slc1a8b
solute carrier family 1 (glutamate transporter), member 8b
chr1_-_45177373 4.50 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr11_-_29082429 4.50 ENSDART00000041443
igsf21a
immunoglobin superfamily, member 21a
chr9_+_33357011 4.48 ENSDART00000088569
nyx
nyctalopin
chr7_+_56615554 4.46 ENSDART00000098430
dpep1
dipeptidase 1
chr3_-_32170850 4.41 ENSDART00000055307
ENSDART00000157366
tnnt1
troponin T type 1 (skeletal, slow)
chr3_-_28828242 4.37 ENSDART00000151445
si:ch211-76l23.4
si:ch211-76l23.4
chr2_+_28995776 4.31 ENSDART00000138733
cdh12a
cadherin 12, type 2a (N-cadherin 2)
chr13_+_1089942 4.21 ENSDART00000054322
cnrip1b
cannabinoid receptor interacting protein 1b
chr11_-_4235811 4.11 ENSDART00000121716
si:ch211-236d3.4
si:ch211-236d3.4
chr17_+_36627099 3.97 ENSDART00000154104
impg1b
interphotoreceptor matrix proteoglycan 1b
chr20_-_33515890 3.87 ENSDART00000159987
si:dkey-65b13.13
si:dkey-65b13.13
chr3_-_49504023 3.85 ENSDART00000168108
prkacaa
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr25_-_19090479 3.84 ENSDART00000027465
ENSDART00000177670
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr6_+_9867426 3.83 ENSDART00000151749
MPP4 (1 of many)
si:ch211-222n4.6
chr3_+_34919810 3.79 ENSDART00000055264
ca10b
carbonic anhydrase Xb
chr20_-_20821783 3.75 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
ckbb
creatine kinase, brain b
chr11_-_29082175 3.74 ENSDART00000123245
igsf21a
immunoglobin superfamily, member 21a
chr12_+_39685485 3.73 ENSDART00000163403
LO017650.1

chr24_-_7777389 3.72 ENSDART00000138541
rpgrip1
RPGR interacting protein 1
chr19_-_9503473 3.72 ENSDART00000091615
iffo1a
intermediate filament family orphan 1a
chr11_+_39672874 3.60 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr22_+_5103349 3.60 ENSDART00000083474
atcaya
ataxia, cerebellar, Cayman type a
chr15_+_37559570 3.53 ENSDART00000085522
hspb6
heat shock protein, alpha-crystallin-related, b6
chr18_+_10784730 3.52 ENSDART00000028938
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr17_+_25289431 3.45 ENSDART00000161002
kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr10_+_29963518 3.45 ENSDART00000011317
ENSDART00000099964
ENSDART00000182990
ENSDART00000113912
ntm
neurotrimin
chr21_-_28235361 3.44 ENSDART00000164458
nrxn2a
neurexin 2a
chr17_+_16564921 3.43 ENSDART00000151904
foxn3
forkhead box N3
chr23_-_7125494 3.38 ENSDART00000111929
slco4a1
solute carrier organic anion transporter family, member 4A1
chr15_-_26636826 3.29 ENSDART00000087632
slc47a4
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr1_-_46859398 3.27 ENSDART00000135795
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr24_+_24923166 3.21 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr2_+_25929619 3.09 ENSDART00000137746
slc7a14a
solute carrier family 7, member 14a
chr3_-_33574576 3.08 ENSDART00000184881
CR847537.1

chr5_-_17876709 2.96 ENSDART00000141978
si:dkey-112e17.1
si:dkey-112e17.1
chr20_-_1141722 2.96 ENSDART00000152675
gabrr1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr17_-_31058900 2.94 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
eml1
echinoderm microtubule associated protein like 1
chr4_-_18436899 2.92 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr17_+_16565185 2.91 ENSDART00000136874
foxn3
forkhead box N3
chr13_+_12528043 2.91 ENSDART00000057761
rrh
retinal pigment epithelium-derived rhodopsin homolog
chr10_-_21054059 2.89 ENSDART00000139733
pcdh1a
protocadherin 1a
chr8_+_23142946 2.78 ENSDART00000152933
si:ch211-196c10.13
si:ch211-196c10.13
chr5_-_69180587 2.70 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr7_-_49594995 2.65 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr2_-_48171112 2.64 ENSDART00000156258
pfkpb
phosphofructokinase, platelet b
chr13_-_36184701 2.63 ENSDART00000146522
map3k9
mitogen-activated protein kinase kinase kinase 9
chr7_-_53117131 2.62 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr14_+_909769 2.60 ENSDART00000021346
ENSDART00000172777
arl3l2
ADP-ribosylation factor-like 3, like 2
chr2_-_1569250 2.56 ENSDART00000167202
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr14_-_36378494 2.50 ENSDART00000058503
gpm6aa
glycoprotein M6Aa
chr11_-_28148033 2.50 ENSDART00000177182
lactbl1b
lactamase, beta-like 1b
chr14_-_30587814 2.47 ENSDART00000144912
ENSDART00000149714
tmem265
transmembrane protein 265
chr2_-_30784198 2.43 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr7_-_66864756 2.42 ENSDART00000184462
ENSDART00000189424
ampd3a
adenosine monophosphate deaminase 3a
chr17_-_20979077 2.41 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr12_-_10275320 2.41 ENSDART00000170078
mpp2b
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr6_+_32415132 2.41 ENSDART00000155790
kank4
KN motif and ankyrin repeat domains 4
chr17_+_50701748 2.40 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr9_+_13682133 2.38 ENSDART00000175639
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr20_-_34754617 2.34 ENSDART00000148066
znf395b
zinc finger protein 395b
chr25_+_29688671 2.32 ENSDART00000073478
brd1b
bromodomain containing 1b
chr23_-_35195908 2.30 ENSDART00000122429
klf15
Kruppel-like factor 15
chr15_-_17074393 2.28 ENSDART00000155526
si:ch211-24o10.6
si:ch211-24o10.6
chr18_-_22753637 2.24 ENSDART00000181589
ENSDART00000009912
hsf4
heat shock transcription factor 4
chr15_-_23467750 2.22 ENSDART00000148804
pdzd3a
PDZ domain containing 3a
chr14_-_2400668 2.20 ENSDART00000172717
ENSDART00000182882
si:ch73-233f7.1
si:ch73-233f7.1
chr7_-_28058442 2.17 ENSDART00000173842
si:ch211-235p24.2
si:ch211-235p24.2
chr8_+_4337312 2.17 ENSDART00000182228
myl2b
myosin, light chain 2b, regulatory, cardiac, slow
chr11_-_40257225 2.14 ENSDART00000139009
TRIM62 (1 of many)
si:ch211-193i15.2
chr2_-_15318786 2.10 ENSDART00000135851
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr5_-_69180227 2.08 ENSDART00000154816
zgc:171967
zgc:171967
chr2_+_31476065 2.05 ENSDART00000049219
cacnb2b
calcium channel, voltage-dependent, beta 2b
chr14_+_21699414 2.02 ENSDART00000169942
stx3a
syntaxin 3A
chr2_-_48171441 1.99 ENSDART00000123040
pfkpb
phosphofructokinase, platelet b
chr9_-_18568927 1.96 ENSDART00000084668
enox1
ecto-NOX disulfide-thiol exchanger 1
chr14_-_25034142 1.95 ENSDART00000000392
pde6a
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr20_-_16548912 1.95 ENSDART00000137601
ches1
checkpoint suppressor 1
chr9_+_7724152 1.95 ENSDART00000061716
mnx2a
motor neuron and pancreas homeobox 2a
chr16_-_33059246 1.89 ENSDART00000171718
ENSDART00000168305
ENSDART00000166401
snap91
synaptosomal-associated protein 91
chr5_-_30074332 1.88 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr20_-_9963713 1.87 ENSDART00000104234
gjd2b
gap junction protein delta 2b
chr11_+_2506516 1.87 ENSDART00000130886
ENSDART00000189767
NABP2
si:ch73-190f16.2
chr12_+_41991635 1.87 ENSDART00000186161
ENSDART00000192510
TCERG1L
transcription elongation regulator 1 like
chr7_+_67467702 1.85 ENSDART00000168460
ENSDART00000170322
rpl13
ribosomal protein L13
chr5_+_11407504 1.85 ENSDART00000186723
ENSDART00000018047
zgc:112294
zgc:112294
chr15_+_42599501 1.84 ENSDART00000177646
grik1b
glutamate receptor, ionotropic, kainate 1b
chr10_-_36738619 1.83 ENSDART00000093000
ENSDART00000157179
PLEKHB1
si:ch211-176g13.7
chr13_-_47800342 1.81 ENSDART00000121817
fbln7
fibulin 7
chr19_-_2115040 1.81 ENSDART00000020497
snx13
sorting nexin 13
chr7_-_52842605 1.80 ENSDART00000083002
map1aa
microtubule-associated protein 1Aa
chr10_-_18468385 1.80 ENSDART00000183302
si:dkey-28o19.1
si:dkey-28o19.1
chr1_-_11075403 1.80 ENSDART00000102903
ENSDART00000170290
dmd
dystrophin
chr6_+_36795225 1.73 ENSDART00000171504
si:ch73-29l19.1
si:ch73-29l19.1
chr25_-_16818380 1.72 ENSDART00000155401
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr9_+_11034967 1.61 ENSDART00000152081
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr1_+_55758257 1.59 ENSDART00000139312
tecrb
trans-2,3-enoyl-CoA reductase b
chr23_-_27050083 1.48 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
zgc:66440
chr25_-_16818195 1.46 ENSDART00000185215
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr15_-_24883956 1.46 ENSDART00000113199
aipl1
aryl hydrocarbon receptor interacting protein-like 1
chr2_+_30878864 1.45 ENSDART00000009326
oprk1
opioid receptor, kappa 1
chr13_+_45582391 1.44 ENSDART00000058093
ldlrap1b
low density lipoprotein receptor adaptor protein 1b
chr22_+_20427170 1.43 ENSDART00000136744
foxq2
forkhead box Q2
chr3_-_28665291 1.42 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr8_+_53928472 1.41 ENSDART00000063242
MMP23B
matrix metallopeptidase 23B
chr15_-_38154616 1.41 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr10_-_25561751 1.40 ENSDART00000147089
grik1a
glutamate receptor, ionotropic, kainate 1a
chr16_+_11151699 1.39 ENSDART00000140674
cicb
capicua transcriptional repressor b
chr14_-_32503363 1.37 ENSDART00000034883
mcf2a
MCF.2 cell line derived transforming sequence a
chr25_+_19041329 1.37 ENSDART00000153467
lrtm2b
leucine-rich repeats and transmembrane domains 2b
chr5_+_22510639 1.29 ENSDART00000080919
rpl36a
ribosomal protein L36A
chr13_-_36525982 1.26 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr7_+_4384863 1.24 ENSDART00000042955
ENSDART00000134653
slc12a10.3
slc12a10.3 solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 3
chr11_+_25303839 1.20 ENSDART00000162149
top1l
DNA topoisomerase I, like
chr18_+_7594012 1.13 ENSDART00000062150
zgc:77752
zgc:77752
chr7_+_30970045 1.11 ENSDART00000155974
tjp1a
tight junction protein 1a
chr25_-_35996141 1.11 ENSDART00000149074
sall1b
spalt-like transcription factor 1b
chr19_+_4061699 1.10 ENSDART00000158309
ENSDART00000166512
btr25
btr26
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr25_+_33002963 1.10 ENSDART00000187366
CABZ01046980.1

chr7_-_35516251 1.07 ENSDART00000045628
irx6a
iroquois homeobox 6a
chr17_-_21617618 1.03 ENSDART00000109031
gpr26
G protein-coupled receptor 26
chr3_-_61593274 0.95 ENSDART00000154132
ENSDART00000055071
nptx2a
neuronal pentraxin 2a
chr1_-_26293203 0.90 ENSDART00000180140
cxxc4
CXXC finger 4
chr3_+_18097700 0.90 ENSDART00000021634
wfikkn2a
info WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2a
chr20_-_43663494 0.89 ENSDART00000144564
BX470188.1

chr20_+_35998073 0.88 ENSDART00000140457
opn5
opsin 5
chr22_-_35006554 0.87 ENSDART00000138639
kcnip2
Kv channel interacting protein 2
chr16_-_37372613 0.83 ENSDART00000124090
si:ch211-208k15.1
si:ch211-208k15.1
chr25_-_7925269 0.83 ENSDART00000014274
glcea
glucuronic acid epimerase a
chr9_-_50001606 0.80 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr24_-_1303935 0.76 ENSDART00000159212
ENSDART00000159267
ENSDART00000164904
nrp1a
neuropilin 1a
chr17_+_18117029 0.72 ENSDART00000154646
ENSDART00000179739
bcl11ba
B cell CLL/lymphoma 11Ba
chr7_-_12821277 0.72 ENSDART00000091584
zgc:158785
zgc:158785
chr6_-_36795111 0.67 ENSDART00000160669
ENSDART00000104256
ENSDART00000187751
ENSDART00000161928
ENSDART00000183264
opa1
optic atrophy 1 (autosomal dominant)
chr22_-_910926 0.66 ENSDART00000180075
FP016205.1

chr25_-_7925019 0.65 ENSDART00000183309
glcea
glucuronic acid epimerase a
chr24_-_18876877 0.64 ENSDART00000186269
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr12_-_10508952 0.64 ENSDART00000152806
zgc:152977
zgc:152977
chr9_+_50001746 0.63 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr19_-_8880688 0.62 ENSDART00000039629
celf3a
cugbp, Elav-like family member 3a
chr22_+_16446052 0.61 ENSDART00000142454
si:dkey-121a11.3
si:dkey-121a11.3
chr4_+_9836465 0.60 ENSDART00000004879
hsp90b1
heat shock protein 90, beta (grp94), member 1
chr7_-_35515931 0.60 ENSDART00000193324
irx6a
iroquois homeobox 6a
chr7_+_39011852 0.60 ENSDART00000093009
dgkza
diacylglycerol kinase, zeta a
chr2_+_45159855 0.60 ENSDART00000056333
CU929150.1

chr9_-_14084743 0.59 ENSDART00000056105
fer1l6
fer-1-like family member 6
chr24_-_18877118 0.57 ENSDART00000092783
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chrM_+_15308 0.57 ENSDART00000093625
mt-cyb
cytochrome b, mitochondrial
chr19_+_43884120 0.55 ENSDART00000139684
ENSDART00000142312
lypla2
lysophospholipase II
chr7_+_39011355 0.51 ENSDART00000173855
dgkza
diacylglycerol kinase, zeta a
chr18_+_19006063 0.50 ENSDART00000135729
slc24a1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr1_+_55080797 0.50 ENSDART00000077390
lgalsla
lectin, galactoside-binding-like a
chr18_+_5172848 0.48 ENSDART00000190642
CABZ01080599.1

chr12_+_15622621 0.47 ENSDART00000079784
plcd3b
phospholipase C, delta 3b
chr17_-_50010121 0.47 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr16_-_25206048 0.45 ENSDART00000188896
BX571853.2

chr21_-_41369539 0.42 ENSDART00000187546
cpeb4b
cytoplasmic polyadenylation element binding protein 4b
chr24_-_6260333 0.42 ENSDART00000136041
myo3a
myosin IIIA
chr6_+_36942966 0.40 ENSDART00000028895
negr1
neuronal growth regulator 1
chr23_-_28294763 0.40 ENSDART00000139537
znf385a
zinc finger protein 385A
chr12_+_804314 0.39 ENSDART00000082169
wfikkn2b
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b
chr7_-_17780048 0.38 ENSDART00000183336
si:dkey-106g10.7
si:dkey-106g10.7
chr23_-_24394719 0.38 ENSDART00000044918
epha2b
eph receptor A2 b
chr23_+_19655301 0.38 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr24_+_3478871 0.36 ENSDART00000111491
ENSDART00000134598
ENSDART00000142407
wdr37
WD repeat domain 37
chr13_-_36184476 0.35 ENSDART00000057185
map3k9
mitogen-activated protein kinase kinase kinase 9
chr3_-_10970502 0.35 ENSDART00000127500
CR382337.1

chr20_+_53278746 0.33 ENSDART00000074249
gpr6
G protein-coupled receptor 6
chr25_-_22889519 0.29 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr23_-_4975452 0.29 ENSDART00000105241
ENSDART00000169978
ngfa
nerve growth factor a (beta polypeptide)
chr11_+_25504215 0.27 ENSDART00000154213
tfe3b
transcription factor binding to IGHM enhancer 3b

Network of associatons between targets according to the STRING database.

First level regulatory network of otx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
1.2 4.9 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.7 2.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.7 3.0 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.7 8.5 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.6 4.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.6 1.8 GO:0010664 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.5 4.9 GO:0006833 water transport(GO:0006833)
0.5 4.2 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.4 6.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 2.6 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.4 4.6 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.4 2.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.4 2.0 GO:0007624 ultradian rhythm(GO:0007624)
0.4 10.3 GO:0007634 optokinetic behavior(GO:0007634)
0.4 1.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.4 1.8 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 3.7 GO:0046548 retinal rod cell development(GO:0046548)
0.3 3.6 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.3 2.6 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3 0.9 GO:0016038 absorption of visible light(GO:0016038)
0.3 3.7 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 2.9 GO:0036368 cone photoresponse recovery(GO:0036368)
0.3 3.8 GO:0046549 retinal cone cell development(GO:0046549)
0.2 8.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 7.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 1.9 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.2 2.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.2 3.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 3.8 GO:0010737 protein kinase A signaling(GO:0010737)
0.2 2.4 GO:0032264 IMP salvage(GO:0032264)
0.2 0.5 GO:0060292 long term synaptic depression(GO:0060292)
0.2 2.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 7.8 GO:0007602 phototransduction(GO:0007602)
0.2 0.8 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.2 2.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.8 GO:0007525 somatic muscle development(GO:0007525)
0.1 3.0 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 4.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.7 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 3.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 1.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.6 GO:0035889 otolith tethering(GO:0035889)
0.1 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 5.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 2.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 3.8 GO:0036269 swimming behavior(GO:0036269)
0.1 6.3 GO:0007098 centrosome cycle(GO:0007098)
0.1 9.3 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.1 2.4 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 2.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.2 GO:0006265 DNA topological change(GO:0006265)
0.1 1.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.1 5.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 1.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 9.6 GO:0007601 visual perception(GO:0007601)
0.1 2.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 3.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 1.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 1.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 9.4 GO:0008154 actin polymerization or depolymerization(GO:0008154)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 3.6 GO:0006865 amino acid transport(GO:0006865)
0.0 1.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 5.7 GO:0045087 innate immune response(GO:0045087)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0031673 H zone(GO:0031673)
1.0 6.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.8 18.1 GO:0060170 ciliary membrane(GO:0060170)
0.5 4.0 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.4 4.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.4 13.0 GO:0035869 ciliary transition zone(GO:0035869)
0.4 2.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 3.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 10.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 2.5 GO:0044295 axonal growth cone(GO:0044295)
0.2 5.0 GO:0043195 terminal bouton(GO:0043195)
0.2 1.9 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.9 GO:0005922 connexon complex(GO:0005922)
0.1 2.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 6.9 GO:0016342 catenin complex(GO:0016342)
0.1 14.0 GO:0045177 apical part of cell(GO:0045177)
0.1 4.4 GO:0005861 troponin complex(GO:0005861)
0.1 3.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 5.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 3.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.6 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 3.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 5.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 2.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 4.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 8.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 3.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 3.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.0 GO:0005912 adherens junction(GO:0005912)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.4 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.2 GO:0005502 11-cis retinal binding(GO:0005502)
1.8 5.3 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.9 4.5 GO:0070573 metallodipeptidase activity(GO:0070573)
0.8 3.8 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.7 2.2 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.7 2.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.6 3.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.5 4.9 GO:0015250 water channel activity(GO:0015250)
0.4 4.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 5.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.4 1.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.4 1.5 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.4 2.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.3 6.3 GO:0005080 protein kinase C binding(GO:0005080)
0.3 3.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.3 3.6 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.3 3.7 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 4.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 3.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 0.7 GO:1901612 cardiolipin binding(GO:1901612)
0.2 2.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.9 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2 8.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 3.3 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.2 4.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 2.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 4.4 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.5 GO:0004985 opioid receptor activity(GO:0004985)
0.2 3.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 8.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 2.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.2 6.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 2.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 3.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 7.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 1.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 3.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.4 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 5.9 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.1 0.6 GO:0043495 protein anchor(GO:0043495)
0.1 14.8 GO:0015293 symporter activity(GO:0015293)
0.1 5.0 GO:0019905 syntaxin binding(GO:0019905)
0.1 5.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 3.5 GO:0071949 FAD binding(GO:0071949)
0.1 3.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 3.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 2.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.7 GO:0008201 heparin binding(GO:0008201)
0.0 7.4 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 3.1 GO:0045296 cadherin binding(GO:0045296)
0.0 1.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0030553 cGMP binding(GO:0030553)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 1.3 GO:0044325 ion channel binding(GO:0044325)
0.0 1.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 3.9 GO:0042802 identical protein binding(GO:0042802)
0.0 3.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 4.7 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.8 GO:0035091 phosphatidylinositol binding(GO:0035091)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 15.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 1.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 4.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 2.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 18.1 REACTOME OPSINS Genes involved in Opsins
0.9 2.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4 3.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.3 4.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 6.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 3.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.0 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 3.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events