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PRJEB1986: zebrafish developmental stages transcriptome

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Results for otx5

Z-value: 0.85

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Transcription factors associated with otx5

Gene Symbol Gene ID Gene Info
otx5
ENSDARG00000043483 orthodenticle homolog 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx5dr11_v1_chr15_+_47903864_47903864-0.272.7e-01Click!

Activity profile of otx5 motif

Sorted Z-values of otx5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_25737452 1.70 ENSDART00000152021
si:ch211-214p16.3
si:ch211-214p16.3
chr4_+_18804317 1.64 ENSDART00000101043
slc26a3.2
solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2
chr18_-_40684756 1.46 ENSDART00000113799
ENSDART00000139042
si:ch211-132b12.7
si:ch211-132b12.7
chr13_+_23176330 1.44 ENSDART00000168351
sorbs1
sorbin and SH3 domain containing 1
chr19_-_2115040 1.31 ENSDART00000020497
snx13
sorting nexin 13
chr17_+_50701748 1.10 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr15_-_5815006 1.03 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr2_-_48171112 1.02 ENSDART00000156258
pfkpb
phosphofructokinase, platelet b
chr3_-_49138004 0.99 ENSDART00000167173
gipc1
GIPC PDZ domain containing family, member 1
chr23_+_39963599 0.98 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr17_-_6730247 0.98 ENSDART00000031091
vsnl1b
visinin-like 1b
chr4_-_8030583 0.97 ENSDART00000113628
si:ch211-240l19.8
si:ch211-240l19.8
chr25_-_17552299 0.95 ENSDART00000154327
si:dkey-44k1.5
si:dkey-44k1.5
chr1_-_58009216 0.95 ENSDART00000143829
nxnl1
nucleoredoxin like 1
chr11_+_25583950 0.94 ENSDART00000111961
ccdc120
coiled-coil domain containing 120
chr2_+_7192966 0.94 ENSDART00000142735
si:ch211-13f8.1
si:ch211-13f8.1
chr23_+_39854566 0.92 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
si:ch73-217b7.1
chr23_-_40250886 0.92 ENSDART00000041912
tgm1l3
transglutaminase 1 like 3
chr8_+_2656231 0.92 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr1_-_53407448 0.91 ENSDART00000160033
ENSDART00000172322
elmod2
ELMO/CED-12 domain containing 2
chr10_+_32683089 0.91 ENSDART00000063551
ppm1e
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr15_-_47115787 0.90 ENSDART00000192601
CABZ01079081.1

chr9_-_27442339 0.86 ENSDART00000138602
stxbp5l
syntaxin binding protein 5-like
chr7_-_72208248 0.85 ENSDART00000108916
zmp:0000001168
zmp:0000001168
chr3_+_49521106 0.83 ENSDART00000162799
crb3a
crumbs homolog 3a
chr18_+_2189211 0.82 ENSDART00000170827
ccpg1
cell cycle progression 1
chr3_+_3610140 0.81 ENSDART00000104977
pick1
protein interacting with prkca 1
chr11_+_6152643 0.81 ENSDART00000012789
slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr1_-_46859398 0.79 ENSDART00000135795
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr2_+_51783120 0.77 ENSDART00000177559
crygn1
crystallin, gamma N1
chr8_+_36560019 0.77 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
sf3a1
splicing factor 3a, subunit 1
chr20_+_29587995 0.75 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr3_+_12725343 0.73 ENSDART00000188583
cyp2k20
cytochrome P450, family 2, subfamily k, polypeptide 20
chr14_+_15620640 0.70 ENSDART00000188867
si:dkey-203a12.9
si:dkey-203a12.9
chr9_-_12574473 0.69 ENSDART00000191372
ENSDART00000193667
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr19_-_9503473 0.69 ENSDART00000091615
iffo1a
intermediate filament family orphan 1a
chr1_-_11075403 0.68 ENSDART00000102903
ENSDART00000170290
dmd
dystrophin
chr21_-_3770636 0.64 ENSDART00000053596
scamp1
secretory carrier membrane protein 1
chr7_-_6592142 0.64 ENSDART00000160137
kcnj10a
potassium inwardly-rectifying channel, subfamily J, member 10a
chr8_-_5850472 0.64 ENSDART00000179217
CABZ01102147.1

chr10_+_28428222 0.63 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr9_+_13685921 0.63 ENSDART00000145775
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr4_-_77432218 0.62 ENSDART00000158683
slco1d1
solute carrier organic anion transporter family, member 1D1
chr24_+_37723362 0.62 ENSDART00000136836
rab11fip3
RAB11 family interacting protein 3 (class II)
chr23_+_39558508 0.62 ENSDART00000017902
camk1gb
calcium/calmodulin-dependent protein kinase IGb
chr20_-_33566640 0.61 ENSDART00000159729
si:dkey-65b13.9
si:dkey-65b13.9
chr4_-_47096170 0.61 ENSDART00000161079
si:dkey-26m3.3
si:dkey-26m3.3
chr14_+_26796917 0.59 ENSDART00000137695
klhl4
kelch-like family member 4
chr2_-_48171441 0.58 ENSDART00000123040
pfkpb
phosphofructokinase, platelet b
chr3_+_16762483 0.57 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr17_-_42492668 0.56 ENSDART00000183946
CR925755.2

chr19_-_9760994 0.54 ENSDART00000139727
si:dkey-14o18.2
si:dkey-14o18.2
chr24_-_38079261 0.53 ENSDART00000105662
crp1
C-reactive protein 1
chr22_-_8509215 0.53 ENSDART00000140146
si:ch73-27e22.3
si:ch73-27e22.3
chr23_+_16935494 0.53 ENSDART00000143120
si:dkey-147f3.4
si:dkey-147f3.4
chr14_+_2487672 0.52 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr8_-_50979047 0.51 ENSDART00000184788
ENSDART00000180906
zgc:91909
zgc:91909
chr4_-_75651505 0.50 ENSDART00000115143
si:dkey-71l4.2
si:dkey-71l4.2
chr3_+_48561112 0.50 ENSDART00000159682
slc16a5b
solute carrier family 16 (monocarboxylate transporter), member 5b
chr4_+_75575252 0.50 ENSDART00000166536
si:ch211-227e10.1
si:ch211-227e10.1
chr5_-_1827575 0.50 ENSDART00000171193
mcc
mutated in colorectal cancers
chr4_-_76303301 0.49 ENSDART00000158504
zgc:174944
zgc:174944
chr3_-_55404985 0.48 ENSDART00000154274
mafga
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga
chr17_+_35097024 0.48 ENSDART00000026152
asap2a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr4_+_65487457 0.47 ENSDART00000162017
ENSDART00000193241
si:dkeyp-5g9.1
si:dkeyp-5g9.1
chr6_+_46481024 0.46 ENSDART00000155596
si:dkey-7k24.5
si:dkey-7k24.5
chr21_+_11105007 0.45 ENSDART00000128859
ENSDART00000193105
prlra
prolactin receptor a
chr14_-_2318590 0.45 ENSDART00000192735
pcdh2ab8
protocadherin 2 alpha b 8
chr4_-_63558838 0.45 ENSDART00000191708
ENSDART00000190740
ENSDART00000186476
si:dkey-16p6.1
si:dkey-16p6.1
chr6_-_15604417 0.45 ENSDART00000157817
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr14_+_3038473 0.44 ENSDART00000026021
ENSDART00000150000
cd74a
CD74 molecule, major histocompatibility complex, class II invariant chain a
chr10_+_40204175 0.44 ENSDART00000188277
gramd1ba
GRAM domain containing 1Ba
chr1_+_55080797 0.44 ENSDART00000077390
lgalsla
lectin, galactoside-binding-like a
chr22_+_35516440 0.44 ENSDART00000184191
hykk.2
hydroxylysine kinase, tandem duplicate 2
chr1_+_45217425 0.44 ENSDART00000179983
ENSDART00000074683
EVI5L
si:ch211-239f4.1
chr4_-_71267777 0.43 ENSDART00000169664
si:dkeyp-51g9.4
si:dkeyp-51g9.4
chr4_-_33073382 0.43 ENSDART00000146414
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr3_-_58165254 0.43 ENSDART00000093031
snu13a
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr4_+_58661331 0.42 ENSDART00000188763
CR388148.2

chr16_+_34111919 0.41 ENSDART00000134037
ENSDART00000006061
ENSDART00000140552
tcea3
transcription elongation factor A (SII), 3
chr7_-_17780048 0.41 ENSDART00000183336
si:dkey-106g10.7
si:dkey-106g10.7
chr11_-_3629201 0.41 ENSDART00000136577
ENSDART00000132121
itih3a
inter-alpha-trypsin inhibitor heavy chain 3a
chr17_+_25677458 0.41 ENSDART00000029703
kcnh1a
potassium voltage-gated channel, subfamily H (eag-related), member 1a
chr4_+_45389591 0.40 ENSDART00000162530
si:dkey-16p6.1
si:dkey-16p6.1
chr17_-_7371564 0.40 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr5_+_31791001 0.40 ENSDART00000043010
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr15_-_29510074 0.40 ENSDART00000184070
BX324227.3

chr8_+_54263946 0.40 ENSDART00000193119
TMCC1 (1 of many)
transmembrane and coiled-coil domain family 1
chr4_-_38828508 0.39 ENSDART00000151952
si:dkey-59l11.10
si:dkey-59l11.10
chr6_+_20650003 0.39 ENSDART00000049465
slc19a1
solute carrier family 19 (folate transporter), member 1
chr10_-_20445549 0.38 ENSDART00000064613
loxl2a
lysyl oxidase-like 2a
chr13_-_14269626 0.37 ENSDART00000079176
gfra4a
GDNF family receptor alpha 4a
chr6_-_59381391 0.37 ENSDART00000157066
ppp1r16b
protein phosphatase 1, regulatory subunit 16B
chr3_+_26144765 0.36 ENSDART00000146267
ENSDART00000043932
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr10_+_39476432 0.36 ENSDART00000190375
ENSDART00000183954
kirrel3a
kirre like nephrin family adhesion molecule 3a
chr4_+_58667348 0.36 ENSDART00000186596
ENSDART00000180673
CR388148.2

chr16_-_40043322 0.36 ENSDART00000145278
si:dkey-29b11.3
si:dkey-29b11.3
chr5_-_69180587 0.35 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr19_+_42694211 0.35 ENSDART00000180153
clasp2
cytoplasmic linker associated protein 2
chr4_+_49664256 0.34 ENSDART00000155251
znf974
zinc finger protein 974
chr25_-_34632050 0.34 ENSDART00000170671
megf8
multiple EGF-like-domains 8
chr4_+_65271779 0.33 ENSDART00000134257
znf1027
zinc finger protein 1027
chr2_+_30878864 0.33 ENSDART00000009326
oprk1
opioid receptor, kappa 1
chr4_+_35227135 0.33 ENSDART00000161023
ENSDART00000182403
si:ch211-276i6.1
si:ch211-276i6.1
chr18_-_42071876 0.33 ENSDART00000193288
ENSDART00000189021
ENSDART00000019245
arhgap42b
Rho GTPase activating protein 42b
chr15_+_40079468 0.33 ENSDART00000154947
ngef
neuronal guanine nucleotide exchange factor
chr4_-_67984478 0.33 ENSDART00000160623
si:ch211-223k15.1
si:ch211-223k15.1
chr4_-_52783184 0.32 ENSDART00000172283
si:dkey-4j21.2
si:dkey-4j21.2
chr13_+_1015749 0.32 ENSDART00000190982
prokr1b
prokineticin receptor 1b
chr17_+_4578552 0.32 ENSDART00000038730
ENSDART00000182146
zmp:0000000619
zmp:0000000619
chr10_-_26218354 0.32 ENSDART00000180764
arfip2b
ADP-ribosylation factor interacting protein 2b
chr3_-_18274691 0.32 ENSDART00000161140
BX649434.3

chr4_-_76105527 0.32 ENSDART00000159108
zgc:110171
zgc:110171
chr10_-_36738619 0.31 ENSDART00000093000
ENSDART00000157179
PLEKHB1
si:ch211-176g13.7
chr23_-_7797207 0.31 ENSDART00000181611
myt1b
myelin transcription factor 1b
chr18_+_6641542 0.31 ENSDART00000160379
c2cd5
C2 calcium-dependent domain containing 5
chr15_-_568645 0.31 ENSDART00000156744
cbln18
cerebellin 18
chr7_-_59515569 0.30 ENSDART00000163343
ENSDART00000165457
ENSDART00000163745
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr9_+_1313418 0.29 ENSDART00000191361
casp8l2
caspase 8, apoptosis-related cysteine peptidase, like 2
chr1_+_14348399 0.29 ENSDART00000064468
crmp1
collapsin response mediator protein 1
chr22_+_38164486 0.29 ENSDART00000137521
tm4sf18
transmembrane 4 L six family member 18
chr4_-_70263609 0.29 ENSDART00000163868
si:dkey-3h2.3
si:dkey-3h2.3
chr4_+_52177103 0.29 ENSDART00000166189
si:dkey-16b10.1
si:dkey-16b10.1
chr7_-_48173440 0.29 ENSDART00000124075
mtss1lb
metastasis suppressor 1-like b
chr5_-_30074332 0.28 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr5_+_20148671 0.28 ENSDART00000143205
svopa
SV2 related protein a
chr25_+_192116 0.28 ENSDART00000153983
zgc:114188
zgc:114188
chr4_-_63559311 0.28 ENSDART00000164415
si:dkey-16p6.1
si:dkey-16p6.1
chr4_-_71214516 0.27 ENSDART00000169997
si:ch211-205a14.7
si:ch211-205a14.7
chr4_+_45388995 0.27 ENSDART00000150802
si:dkey-16p6.1
si:dkey-16p6.1
chr4_-_43185261 0.27 ENSDART00000150380
si:dkey-16p6.2
si:dkey-16p6.2
chr23_+_7505943 0.27 ENSDART00000135787
hck
HCK proto-oncogene, Src family tyrosine kinase
chr9_+_20519846 0.26 ENSDART00000109680
ENSDART00000142220
vtcn1
V-set domain containing T cell activation inhibitor 1
chr20_-_28931901 0.26 ENSDART00000153082
ENSDART00000046042
susd6
sushi domain containing 6
chr11_+_29671661 0.25 ENSDART00000024318
ENSDART00000165024
rnf207a
ring finger protein 207a
chr4_-_75795899 0.25 ENSDART00000157925
si:dkey-261j11.1
si:dkey-261j11.1
chr23_-_31266586 0.25 ENSDART00000139746
si:dkey-261l7.2
si:dkey-261l7.2
chr4_-_38829098 0.24 ENSDART00000151932
si:dkey-59l11.10
si:dkey-59l11.10
chr3_+_832788 0.24 ENSDART00000193025
FP102888.2

chr3_+_35608385 0.24 ENSDART00000193219
ENSDART00000132703
traf7
TNF receptor-associated factor 7
chr16_+_52343905 0.24 ENSDART00000131051
ifnlr1
interferon lambda receptor 1
chr7_-_65114067 0.24 ENSDART00000110614
ENSDART00000098277
tmem41b
transmembrane protein 41B
chr3_+_59851537 0.24 ENSDART00000180997
CU693479.1

chr15_-_40065265 0.24 ENSDART00000063781
ENSDART00000142394
gpr55a
G protein-coupled receptor 55a
chr4_+_33818711 0.23 ENSDART00000186452
znf1026
zinc finger protein 1026
chr5_-_67145505 0.23 ENSDART00000011295
rom1a
retinal outer segment membrane protein 1a
chr4_-_49133107 0.23 ENSDART00000150806
znf1146
zinc finger protein 1146
chr6_+_32834760 0.23 ENSDART00000121562
cyldl
cylindromatosis (turban tumor syndrome), like
chr21_-_42007213 0.23 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gabrg2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr4_-_38539463 0.23 ENSDART00000158211
si:ch211-209n20.3
si:ch211-209n20.3
chr4_+_51201875 0.22 ENSDART00000189875
ENSDART00000186722
BX005380.1

chr4_-_4387012 0.22 ENSDART00000191836
CU468826.3
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr17_-_51893123 0.22 ENSDART00000103350
ENSDART00000017329
numb
numb homolog (Drosophila)
chr12_+_3912544 0.22 ENSDART00000013465
tbx6
T-box 6
chr4_-_43919994 0.22 ENSDART00000150297
znf1104
zinc finger protein 1104
chr4_+_25558849 0.22 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
zgc:195175
chr4_-_76186742 0.22 ENSDART00000163970
si:ch211-106j21.4
si:ch211-106j21.4
chr4_-_71416263 0.22 ENSDART00000159812
si:ch211-76m11.15
si:ch211-76m11.15
chr19_+_14921000 0.21 ENSDART00000144052
oprd1a
opioid receptor, delta 1a
chr14_+_15430991 0.21 ENSDART00000158221
si:dkey-203a12.5
si:dkey-203a12.5
chr5_-_69180227 0.21 ENSDART00000154816
zgc:171967
zgc:171967
chr4_-_33763221 0.21 ENSDART00000132613
ENSDART00000191816
ENSDART00000188473
si:ch211-197f20.1
si:ch211-197f20.1
chr1_+_8111009 0.21 ENSDART00000152192
SLC5A10
si:dkeyp-9d4.5
chr9_-_3519253 0.21 ENSDART00000169586
dcaf17
ddb1 and cul4 associated factor 17
chr19_-_35340027 0.21 ENSDART00000146394
macf1a
microtubule-actin crosslinking factor 1a
chr4_+_71014655 0.21 ENSDART00000170837
si:dkeyp-80d11.14
si:dkeyp-80d11.14
chr4_-_56103062 0.20 ENSDART00000165784
ENSDART00000190846
si:dkey-16p6.1
si:dkey-16p6.1
chr1_+_8110562 0.20 ENSDART00000112160
SLC5A10
si:dkeyp-9d4.5
chr4_+_60428812 0.20 ENSDART00000162049
si:dkey-16p6.1
si:dkey-16p6.1
chr4_+_64755464 0.20 ENSDART00000129549
znf1018
zinc finger protein 1018
chr11_-_3366782 0.20 ENSDART00000127982
suox
sulfite oxidase
chr4_+_67994238 0.19 ENSDART00000160968
si:ch211-133h13.1
si:ch211-133h13.1
chr4_+_43245188 0.19 ENSDART00000150310
si:dkey-29j8.1
si:dkey-29j8.1
chr3_+_9071806 0.19 ENSDART00000162372
znf985
zinc finger protein 985
chr16_+_52999778 0.18 ENSDART00000011506
nkd2a
naked cuticle homolog 2a
chr15_-_19669770 0.18 ENSDART00000152707
si:dkey-4p15.3
si:dkey-4p15.3
chr4_-_51045333 0.18 ENSDART00000150560
znf1026
zinc finger protein 1026
chr4_-_63769637 0.18 ENSDART00000158757
znf1098
zinc finger protein 1098
chr4_+_69712223 0.18 ENSDART00000163035
ENSDART00000164475
si:dkey-238o14.1
zgc:174944
si:dkey-238o14.1
zgc:174944
chr4_+_76973771 0.18 ENSDART00000142978
si:dkey-240n22.3
si:dkey-240n22.3
chr13_+_22863516 0.18 ENSDART00000113082
ENSDART00000189200
hnrnph3
heterogeneous nuclear ribonucleoprotein H3 (2H9)
chr4_+_62431132 0.18 ENSDART00000160226
si:ch211-79g12.1
si:ch211-79g12.1
chr8_-_43574935 0.18 ENSDART00000051139
ncor2
nuclear receptor corepressor 2
chr4_+_47782411 0.17 ENSDART00000161728
si:ch211-196h24.2
si:ch211-196h24.2
chr4_+_43225728 0.17 ENSDART00000158639
ENSDART00000141339
ENSDART00000137770
ENSDART00000166019
si:ch211-76m11.5
si:ch211-76m11.5
chr4_-_71471302 0.16 ENSDART00000187687
si:ch211-76m11.5
si:ch211-76m11.5
chr1_-_633356 0.16 ENSDART00000171019
appa
amyloid beta (A4) precursor protein a
chr15_+_5973909 0.16 ENSDART00000126886
ENSDART00000189618
igsf5b
immunoglobulin superfamily, member 5b
chr4_-_43919359 0.16 ENSDART00000184163
ENSDART00000158019
ENSDART00000191745
ENSDART00000181638
ENSDART00000150827
znf1104
zinc finger protein 1104
chr15_+_45640906 0.16 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr7_-_12789251 0.15 ENSDART00000052750
adamtsl3
ADAMTS-like 3
chr20_-_25412181 0.15 ENSDART00000062780
itsn2a
intersectin 2a
chr9_+_3519191 0.15 ENSDART00000008606
mettl8
methyltransferase like 8
chr4_+_70341246 0.15 ENSDART00000123408
si:ch211-76m11.3
si:ch211-76m11.3
chr14_+_43554490 0.15 ENSDART00000060351
adra1bb
adrenoceptor alpha 1Bb
chr17_-_8592824 0.14 ENSDART00000127022
CU462878.1

chr8_+_23391263 0.14 ENSDART00000149687
si:dkey-16n15.6
si:dkey-16n15.6
chr4_-_39186893 0.14 ENSDART00000150371
ENSDART00000121804
ENSDART00000133901
si:ch211-22k7.9
si:ch211-22k7.9
chr21_-_33126697 0.14 ENSDART00000189293
ENSDART00000084559
CU019662.1

chr4_-_47095583 0.14 ENSDART00000183595
ENSDART00000183279
ENSDART00000191638
si:dkey-26m3.3
si:dkey-26m3.3

Network of associatons between targets according to the STRING database.

First level regulatory network of otx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0010658 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.4 1.5 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.2 1.0 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:0010935 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.5 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.8 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.1 0.4 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 0.8 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.6 GO:0036268 swimming(GO:0036268)
0.1 0.4 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.9 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.3 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0021576 hindbrain formation(GO:0021576)
0.0 0.8 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.8 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 1.1 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0030431 sleep(GO:0030431)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.8 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.9 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.4 GO:0032438 melanosome organization(GO:0032438)
0.0 0.1 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.0 0.7 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.3 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.7 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 1.2 GO:0031023 microtubule organizing center organization(GO:0031023)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.4 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.9 GO:0006469 negative regulation of protein kinase activity(GO:0006469)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.8 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.4 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 0.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.4 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 1.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.4 GO:0019202 amino acid kinase activity(GO:0019202)
0.1 0.9 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.2 GO:0038046 enkephalin receptor activity(GO:0038046)
0.1 0.6 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.0 0.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.3 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling