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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pax10+pax6a+pax6b

Z-value: 0.63

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Transcription factors associated with pax10+pax6a+pax6b

Gene Symbol Gene ID Gene Info
pax6b
ENSDARG00000045936 paired box 6b
pax10
ENSDARG00000053364 paired box 10
pax6a
ENSDARG00000103379 paired box 6a
pax10
ENSDARG00000111379 paired box 10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax10dr11_v1_chr3_+_32553714_325537140.597.7e-03Click!
pax6adr11_v1_chr25_-_15040369_150404420.561.2e-02Click!
pax6bdr11_v1_chr7_+_15871156_158711560.213.9e-01Click!

Activity profile of pax10+pax6a+pax6b motif

Sorted Z-values of pax10+pax6a+pax6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_8053385 1.77 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr10_-_8046764 1.51 ENSDART00000099031
zgc:136254
zgc:136254
chr12_-_35949936 1.19 ENSDART00000192583
AL954682.1

chr10_-_8053753 1.19 ENSDART00000162289
si:ch211-251f6.7
si:ch211-251f6.7
chr25_-_27842654 1.03 ENSDART00000154852
ENSDART00000156906
asb15a
ankyrin repeat and SOCS box containing 15a
chr13_-_22862133 0.89 ENSDART00000138563
pbld2
phenazine biosynthesis-like protein domain containing 2
chr2_-_32768951 0.78 ENSDART00000004712
bfsp2
beaded filament structural protein 2, phakinin
chr16_-_31188715 0.77 ENSDART00000058829
scrt1b
scratch family zinc finger 1b
chr13_-_32726178 0.72 ENSDART00000012232
pdss2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr5_-_51619742 0.71 ENSDART00000188537
otpb
orthopedia homeobox b
chr22_+_18389271 0.67 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr3_+_35298078 0.64 ENSDART00000110126
cacng3b
calcium channel, voltage-dependent, gamma subunit 3b
chr11_+_42730639 0.62 ENSDART00000165297
zgc:194981
zgc:194981
chr21_+_23108420 0.60 ENSDART00000192394
ENSDART00000088459
htr3b
5-hydroxytryptamine (serotonin) receptor 3B
chr24_-_41320037 0.55 ENSDART00000129058
rheb
Ras homolog, mTORC1 binding
chr24_+_38306010 0.53 ENSDART00000143184
mybpc2b
myosin binding protein C, fast type b
chr14_-_1454045 0.52 ENSDART00000161460
pmt
phosphoethanolamine methyltransferase
chr10_-_44306399 0.51 ENSDART00000180042
CDK2AP1
cyclin dependent kinase 2 associated protein 1
chr5_+_32162684 0.50 ENSDART00000134472
taok3b
TAO kinase 3b
chr19_-_47526737 0.49 ENSDART00000186636
scg5
secretogranin V
chr9_+_31222026 0.49 ENSDART00000145573
clybl
citrate lyase beta like
chr5_+_23242370 0.48 ENSDART00000051532
agtr2
angiotensin II receptor, type 2
chr20_-_29474859 0.48 ENSDART00000152906
ENSDART00000045249
scg5
secretogranin V
chr10_-_31015535 0.47 ENSDART00000146116
panx3
pannexin 3
chr24_-_6671549 0.46 ENSDART00000114700
unm_sa821
un-named sa821
chr25_+_19105804 0.46 ENSDART00000104414
rlbp1b
retinaldehyde binding protein 1b
chr1_-_12278056 0.45 ENSDART00000139336
ENSDART00000137463
cplx2l
complexin 2, like
chr7_+_21887787 0.45 ENSDART00000162252
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr1_-_59287410 0.45 ENSDART00000158011
ENSDART00000170580
col5a3b
collagen, type V, alpha 3b
chr14_+_20893065 0.44 ENSDART00000079452
lygl1
lysozyme g-like 1
chr12_-_44072716 0.44 ENSDART00000162509
si:ch73-329n5.3
si:ch73-329n5.3
chr21_-_7178348 0.44 ENSDART00000187467
fam69b
family with sequence similarity 69, member B
chr7_+_26762958 0.44 ENSDART00000167956
ENSDART00000134717
tspan18a
tetraspanin 18a
chr18_-_20466061 0.44 ENSDART00000060311
paqr5a
progestin and adipoQ receptor family member Va
chr7_+_17229980 0.43 ENSDART00000184910
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr23_-_27505825 0.43 ENSDART00000137229
ENSDART00000013797
asb8
ankyrin repeat and SOCS box containing 8
chr23_+_44611864 0.42 ENSDART00000145905
ENSDART00000132361
eno3
enolase 3, (beta, muscle)
chr25_+_19106574 0.42 ENSDART00000067332
rlbp1b
retinaldehyde binding protein 1b
chr19_-_41518922 0.42 ENSDART00000164483
ENSDART00000062080
chrac1
chromatin accessibility complex 1
chr23_+_44614056 0.42 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr10_+_26972755 0.42 ENSDART00000042162
tm7sf2
transmembrane 7 superfamily member 2
chr19_-_9829965 0.41 ENSDART00000136842
ENSDART00000142766
cacng8a
calcium channel, voltage-dependent, gamma subunit 8a
chr3_-_26184018 0.40 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr2_+_6991208 0.40 ENSDART00000182239
ddr2b
discoidin domain receptor tyrosine kinase 2b
chr22_+_27090136 0.39 ENSDART00000136770
si:dkey-246e1.3
si:dkey-246e1.3
chr19_+_12444943 0.39 ENSDART00000135706
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr22_-_25033105 0.39 ENSDART00000124220
nptxrb
neuronal pentraxin receptor b
chr5_-_33039670 0.38 ENSDART00000141361
glipr2
GLI pathogenesis-related 2
chr11_-_11336986 0.38 ENSDART00000016677
zgc:77929
zgc:77929
chr6_+_11990733 0.38 ENSDART00000151075
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr8_+_26083808 0.38 ENSDART00000099283
dalrd3
DALR anticodon binding domain containing 3
chr1_+_54908895 0.37 ENSDART00000145652
golga7ba
golgin A7 family, member Ba
chr6_+_42819337 0.37 ENSDART00000046498
sema3fa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr5_-_29750377 0.36 ENSDART00000051474
barhl1a
BarH-like homeobox 1a
chr3_+_43086548 0.36 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr25_-_28926631 0.36 ENSDART00000112850
etfbkmt
electron transfer flavoprotein beta subunit lysine methyltransferase
chr20_-_14680897 0.36 ENSDART00000063857
ENSDART00000161314
scrn2
secernin 2
chr20_+_36233873 0.35 ENSDART00000131867
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr14_+_3495542 0.35 ENSDART00000168934
gstp2
glutathione S-transferase pi 2
chr23_-_36724575 0.35 ENSDART00000159560
agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr5_-_51756210 0.35 ENSDART00000163464
lhfpl2b
LHFPL tetraspan subfamily member 2b
chr2_-_985417 0.35 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr11_-_6265574 0.35 ENSDART00000181974
ENSDART00000104405
ccl25b
chemokine (C-C motif) ligand 25b
chr9_+_23900703 0.35 ENSDART00000127859
trim63b
tripartite motif containing 63b
chr3_+_62353650 0.34 ENSDART00000112428
iqck
IQ motif containing K
chr11_+_24298432 0.34 ENSDART00000138487
si:dkey-76p14.2
si:dkey-76p14.2
chr15_+_5901970 0.34 ENSDART00000114134
wrb
tryptophan rich basic protein
chr21_+_27382893 0.34 ENSDART00000005682
actn3a
actinin alpha 3a
chr12_-_10441661 0.34 ENSDART00000014379
uqcrc2b
ubiquinol-cytochrome c reductase core protein 2b
chr12_+_3571770 0.33 ENSDART00000164707
ENSDART00000189819
coa3a
cytochrome C oxidase assembly factor 3a
chr7_+_48555400 0.33 ENSDART00000174474
kcnq1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr14_-_14659023 0.33 ENSDART00000170355
ENSDART00000159888
ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr24_-_8729531 0.33 ENSDART00000082346
tfap2a
transcription factor AP-2 alpha
chr23_+_36052944 0.32 ENSDART00000103149
hoxc13a
homeobox C13a
chr24_-_36271352 0.32 ENSDART00000153682
ENSDART00000155892
si:ch211-40k21.5
si:ch211-40k21.5
chr11_-_13107106 0.31 ENSDART00000184477
elovl1b
ELOVL fatty acid elongase 1b
chr9_-_19583704 0.31 ENSDART00000053218
tmprss3a
transmembrane protease, serine 3a
chr21_+_5209476 0.31 ENSDART00000146400
st8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr9_-_32847642 0.31 ENSDART00000121506
hpx
hemopexin
chr14_+_22172047 0.31 ENSDART00000114750
ENSDART00000148259
gabrb2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr19_-_25114701 0.31 ENSDART00000149035
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr9_+_43797902 0.30 ENSDART00000020550
ube2e3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr7_+_27250186 0.30 ENSDART00000150068
sox6
SRY (sex determining region Y)-box 6
chr20_+_36234335 0.30 ENSDART00000193484
ENSDART00000181664
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr7_+_50464500 0.30 ENSDART00000191356
serinc4
serine incorporator 4
chr20_-_2134620 0.30 ENSDART00000064375
tmem244
transmembrane protein 244
chr20_-_40451115 0.30 ENSDART00000075092
pkib
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr13_+_27298673 0.29 ENSDART00000142922
slc17a5
solute carrier family 17 (acidic sugar transporter), member 5
chr8_+_38417461 0.29 ENSDART00000132718
nkx6.3
NK6 homeobox 3
chr7_-_8738827 0.29 ENSDART00000172807
ENSDART00000173026
si:ch211-1o7.3
si:ch211-1o7.3
chr24_-_8729716 0.29 ENSDART00000183624
tfap2a
transcription factor AP-2 alpha
chr1_+_51721851 0.29 ENSDART00000040397
prdx2
peroxiredoxin 2
chr17_-_15029258 0.28 ENSDART00000168332
ENSDART00000012877
ENSDART00000109190
ero1a
endoplasmic reticulum oxidoreductase alpha
chr2_-_21349425 0.28 ENSDART00000171699
hhatla
hedgehog acyltransferase like, a
chr4_-_17741513 0.28 ENSDART00000141680
mybpc1
myosin binding protein C, slow type
chr12_-_47793857 0.27 ENSDART00000161294
dydc2
DPY30 domain containing 2
chr13_+_12671513 0.26 ENSDART00000010517
eif4eb
eukaryotic translation initiation factor 4eb
chr21_-_22117085 0.26 ENSDART00000146673
slc35f2
solute carrier family 35, member F2
chr19_-_3726768 0.26 ENSDART00000161738
smim13
small integral membrane protein 13
chr24_-_39186185 0.25 ENSDART00000123019
ENSDART00000191114
nubp2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr23_+_36460239 0.25 ENSDART00000172441
lima1a
LIM domain and actin binding 1a
chr13_-_48388726 0.25 ENSDART00000169473
fbxo11a
F-box protein 11a
chr2_+_2772447 0.25 ENSDART00000124882
thoc1
THO complex 1
chr23_-_18381361 0.25 ENSDART00000016891
hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
chr1_+_40023640 0.25 ENSDART00000101623
lgi2b
leucine-rich repeat LGI family, member 2b
chr10_+_38560032 0.24 ENSDART00000177197
LO018336.1

chr6_-_38418862 0.24 ENSDART00000104135
gabra5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr7_+_21887307 0.24 ENSDART00000052871
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr4_-_13613148 0.23 ENSDART00000067164
ENSDART00000111247
irf5
interferon regulatory factor 5
chr10_-_14556978 0.23 ENSDART00000126643
zgc:153395
zgc:153395
chr4_+_3482312 0.23 ENSDART00000109044
grm8a
glutamate receptor, metabotropic 8a
chr15_-_5252673 0.23 ENSDART00000132963
or126-1
odorant receptor, family E, subfamily 126, member 1
chr25_+_5015019 0.23 ENSDART00000127600
hdac10
histone deacetylase 10
chr21_-_39566854 0.23 ENSDART00000020174
dynll2b
dynein, light chain, LC8-type 2b
chr9_-_1949915 0.23 ENSDART00000190712
hoxd3a
homeobox D3a
chr19_-_10306910 0.22 ENSDART00000151684
u2af2b
U2 small nuclear RNA auxiliary factor 2b
chr25_-_11057753 0.22 ENSDART00000186551
sv2bb
synaptic vesicle glycoprotein 2Bb
chr24_+_11908480 0.22 ENSDART00000024224
fen1
flap structure-specific endonuclease 1
chr11_-_165288 0.22 ENSDART00000108703
ENSDART00000173151
tegt
testis enhanced gene transcript (BAX inhibitor 1)
chr3_+_55093581 0.22 ENSDART00000101709
hbaa2
hemoglobin, alpha adult 2
chr14_-_12390724 0.22 ENSDART00000131343
magt1
magnesium transporter 1
chr9_-_31915423 0.22 ENSDART00000060051
fgf14
fibroblast growth factor 14
chr6_-_58757131 0.22 ENSDART00000083582
soat2
sterol O-acyltransferase 2
chr22_-_36530902 0.22 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr11_-_3897067 0.21 ENSDART00000134858
rpn1
ribophorin I
chr14_+_29609245 0.21 ENSDART00000043058
TENM2
si:dkey-34l15.2
chr22_-_881080 0.21 ENSDART00000185489
cept1b
choline/ethanolamine phosphotransferase 1b
chr1_+_5402476 0.21 ENSDART00000040204
tuba8l2
tubulin, alpha 8 like 2
chr7_-_73843720 0.21 ENSDART00000111622
caap1
caspase activity and apoptosis inhibitor 1
chr25_+_11008419 0.20 ENSDART00000156589
mhc1lia
major histocompatibility complex class I LIA
chr10_+_24690534 0.20 ENSDART00000079549
tpte
transmembrane phosphatase with tensin homology
chr7_-_17814118 0.20 ENSDART00000179688
ecsit
ECSIT signalling integrator
chr8_+_40628926 0.20 ENSDART00000163598
dusp2
dual specificity phosphatase 2
chr14_+_6963312 0.20 ENSDART00000150050
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr15_-_704408 0.20 ENSDART00000156200
ENSDART00000166404
ENSDART00000131040
zgc:174574
zgc:174574
chr13_+_25455319 0.20 ENSDART00000145948
pkd2l1
polycystic kidney disease 2-like 1
chr5_+_41477526 0.19 ENSDART00000153567
pias2
protein inhibitor of activated STAT, 2
chr10_+_37500234 0.19 ENSDART00000132096
ENSDART00000099473
msi2a
musashi RNA-binding protein 2a
chr22_+_28337204 0.19 ENSDART00000163352
impg2b
interphotoreceptor matrix proteoglycan 2b
chr16_-_5105295 0.19 ENSDART00000082071
ENSDART00000148955
ENSDART00000184700
ENSDART00000188127
bckdhb
branched chain keto acid dehydrogenase E1, beta polypeptide
chr5_+_41477954 0.19 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr23_-_19230627 0.19 ENSDART00000007122
guca1b
guanylate cyclase activator 1B
chr25_-_8201983 0.18 ENSDART00000006579
saal1
serum amyloid A-like 1
chr24_+_22021675 0.18 ENSDART00000081234
ropn1l
rhophilin associated tail protein 1-like
chr25_+_4635355 0.18 ENSDART00000021120
pgghg
protein-glucosylgalactosylhydroxylysine glucosidase
chr14_-_858985 0.18 ENSDART00000148687
ENSDART00000149375
slc34a1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr24_+_28383278 0.18 ENSDART00000018095
sh3glb1a
SH3-domain GRB2-like endophilin B1a
chr14_+_31529958 0.18 ENSDART00000053026
fam122b
family with sequence similarity 122B
chr3_-_22366032 0.18 ENSDART00000029849
ifnphi1
interferon phi 1
chr22_+_9091913 0.18 ENSDART00000186598
BX248395.1

chr22_-_15385442 0.18 ENSDART00000090975
tmem264
transmembrane protein 264
chr9_+_23003208 0.17 ENSDART00000021060
eaf2
ELL associated factor 2
chr12_+_25845494 0.17 ENSDART00000170582
glud1b
glutamate dehydrogenase 1b
chr4_-_13931293 0.17 ENSDART00000067172
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr7_+_24496894 0.17 ENSDART00000149994
nelfa
negative elongation factor complex member A
chr19_+_32201991 0.17 ENSDART00000022667
fam8a1a
family with sequence similarity 8, member A1a
chr6_-_37468971 0.17 ENSDART00000126379
plcxd1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr4_-_13931508 0.17 ENSDART00000067174
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr1_-_21409877 0.17 ENSDART00000102782
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr3_-_58189429 0.16 ENSDART00000156092
si:ch211-256e16.11
si:ch211-256e16.11
chr24_+_11908833 0.16 ENSDART00000178622
fen1
flap structure-specific endonuclease 1
chr5_+_38684651 0.16 ENSDART00000137852
si:dkey-58f10.10
si:dkey-58f10.10
chr4_+_74943111 0.16 ENSDART00000004739
nup50
nucleoporin 50
chr5_-_47975440 0.16 ENSDART00000145665
ENSDART00000007057
ccnh
cyclin H
chr5_+_25072894 0.16 ENSDART00000012268
mrpl41
mitochondrial ribosomal protein L41
chr5_-_26330313 0.16 ENSDART00000148656
arvcfb
ARVCF, delta catenin family member b
chr18_-_6151793 0.16 ENSDART00000122307
gcsha
glycine cleavage system protein H (aminomethyl carrier), a
chr11_+_30057762 0.16 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr22_-_3182965 0.16 ENSDART00000158009
lonp1
lon peptidase 1, mitochondrial
chr1_-_26045560 0.16 ENSDART00000172737
ENSDART00000076120
ENSDART00000193593
gpank1
G patch domain and ankyrin repeats 1
chr20_-_25486384 0.15 ENSDART00000141340
si:dkey-183n20.15
si:dkey-183n20.15
chr18_+_62932 0.15 ENSDART00000052638
slc27a2a
solute carrier family 27 (fatty acid transporter), member 2a
chr10_+_18557102 0.15 ENSDART00000160157
CR388008.1

chr22_+_21398508 0.15 ENSDART00000089408
ENSDART00000186091
shdb
Src homology 2 domain containing transforming protein D, b
chr3_-_23513155 0.15 ENSDART00000170200
BX682558.1

chr2_+_46032678 0.15 ENSDART00000184382
ENSDART00000125971
gpc1b
glypican 1b
chr7_+_48555626 0.15 ENSDART00000125483
ENSDART00000083514
kcnq1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr10_+_20392083 0.15 ENSDART00000166867
r3hcc1
R3H domain and coiled-coil containing 1
chr5_+_38631119 0.15 ENSDART00000131832
ENSDART00000162215
si:ch211-271e10.6
si:ch211-271e10.6
chr5_+_32490238 0.15 ENSDART00000191839
ndor1
NADPH dependent diflavin oxidoreductase 1
chr1_+_29162478 0.15 ENSDART00000141441
ankrd10a
ankyrin repeat domain 10a
chr24_+_30695120 0.15 ENSDART00000178649
zgc:174719
zgc:174719
chr9_+_23124252 0.15 ENSDART00000192377
BX936418.1

chr5_+_26807142 0.15 ENSDART00000188981
rabl6b
RAB, member RAS oncogene family-like 6b
chr3_+_25914064 0.15 ENSDART00000162558
ENSDART00000166843
tom1
target of myb1 membrane trafficking protein
chr3_+_24189804 0.14 ENSDART00000134723
prr15la
proline rich 15-like a
chr15_+_9121054 0.14 ENSDART00000193889
ptgir
prostaglandin I2 receptor
chr22_+_29135846 0.14 ENSDART00000143811
baiap2l2b
BAI1-associated protein 2-like 2b
chr14_+_8343498 0.14 ENSDART00000164551
nrg2b
neuregulin 2b
chr11_-_40728380 0.14 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr14_+_30762131 0.14 ENSDART00000145039
si:ch211-145o7.3
si:ch211-145o7.3
chr9_+_8365398 0.14 ENSDART00000138713
ENSDART00000136847
si:dkey-90l23.2
si:dkey-90l23.2
chr7_+_45975537 0.14 ENSDART00000170253
plekhf1
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr19_-_11238620 0.14 ENSDART00000148697
ENSDART00000149169
ssr2
signal sequence receptor, beta
chr14_+_33507608 0.14 ENSDART00000038128
mcts1
malignant T cell amplified sequence 1
chr15_-_1001177 0.14 ENSDART00000160730
zgc:162936
zgc:162936
chr13_-_39159810 0.14 ENSDART00000131508
col9a1b
collagen, type IX, alpha 1b
chr15_-_25319663 0.14 ENSDART00000042218
pafah1b1a
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a
chr2_-_48753873 0.14 ENSDART00000189556
CABZ01044731.1

chr2_+_25657958 0.14 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a

Network of associatons between targets according to the STRING database.

First level regulatory network of pax10+pax6a+pax6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 0.5 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.1 0.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 0.7 GO:0021767 mammillary body development(GO:0021767)
0.1 0.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.1 0.8 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.3 GO:0060254 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.1 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 0.5 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.0 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.4 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.6 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0051230 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.7 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.0 0.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.3 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.1 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508)
0.0 0.1 GO:0010359 regulation of anion channel activity(GO:0010359)
0.0 1.0 GO:0046883 regulation of hormone secretion(GO:0046883)
0.0 0.1 GO:0071548 response to dexamethasone(GO:0071548)
0.0 0.5 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.4 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0014812 muscle cell migration(GO:0014812)
0.0 0.2 GO:0042744 oxygen transport(GO:0015671) hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0044090 positive regulation of vacuole organization(GO:0044090)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.2 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 1.0 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.2 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.2 0.5 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 4.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.5 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.7 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.4 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.2 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.1 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.2 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.4 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.7 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.5 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.2 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 1.3 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.8 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction