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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pax1a+pax1b_pax9

Z-value: 0.56

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Transcription factors associated with pax1a+pax1b_pax9

Gene Symbol Gene ID Gene Info
pax1a
ENSDARG00000008203 paired box 1a
pax1b
ENSDARG00000073814 paired box 1b
pax9
ENSDARG00000053829 paired box 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax1adr11_v1_chr17_+_42274825_42274825-0.589.2e-03Click!
pax1bdr11_v1_chr20_-_48701593_487015930.321.9e-01Click!
pax9dr11_v1_chr17_-_38291065_382910650.116.5e-01Click!

Activity profile of pax1a+pax1b_pax9 motif

Sorted Z-values of pax1a+pax1b_pax9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_7854216 2.40 ENSDART00000149594
ank3b
ankyrin 3b
chr3_+_49021079 2.04 ENSDART00000162012
zgc:163083
zgc:163083
chr20_+_29587995 1.92 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr2_-_44283554 1.34 ENSDART00000184684
mpz
myelin protein zero
chr8_+_48965767 1.32 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr8_+_48966165 1.23 ENSDART00000165425
aak1a
AP2 associated kinase 1a
chr12_-_18483348 1.04 ENSDART00000152757
tex2l
testis expressed 2, like
chr2_-_44282796 0.91 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr1_-_46343999 0.91 ENSDART00000145117
ENSDART00000193233
atp11a
ATPase phospholipid transporting 11A
chr2_+_394166 0.90 ENSDART00000155733
mylk4a
myosin light chain kinase family, member 4a
chr5_-_29643381 0.69 ENSDART00000034849
grin1b
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr21_+_13861589 0.60 ENSDART00000015629
ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr22_+_28337204 0.51 ENSDART00000163352
impg2b
interphotoreceptor matrix proteoglycan 2b
chr25_-_29087925 0.51 ENSDART00000171758
rpp25a
ribonuclease P and MRP subunit p25, a
chr8_-_16650595 0.46 ENSDART00000135319
osbpl9
oxysterol binding protein-like 9
chr6_-_41079209 0.40 ENSDART00000151592
rab44
RAB44, member RAS oncogene family
chr9_+_38074082 0.34 ENSDART00000017833
cacnb4a
calcium channel, voltage-dependent, beta 4a subunit
chr14_+_2487672 0.34 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr5_-_201600 0.33 ENSDART00000158495
CABZ01088906.1

chr25_+_6306885 0.31 ENSDART00000142705
ENSDART00000067510
crabp1a
cellular retinoic acid binding protein 1a
chr7_-_6553460 0.29 ENSDART00000172903
si:ch1073-220m6.1
si:ch1073-220m6.1
chr4_-_52783184 0.29 ENSDART00000172283
si:dkey-4j21.2
si:dkey-4j21.2
chr4_-_8902406 0.21 ENSDART00000192962
mpped1
metallophosphoesterase domain containing 1
chr20_+_12702923 0.21 ENSDART00000163499
zgc:153383
zgc:153383
chr13_-_24379271 0.16 ENSDART00000046360
rhoua
ras homolog family member Ua
chr14_+_23518110 0.15 ENSDART00000112930
si:ch211-221f10.2
si:ch211-221f10.2
chr6_-_31224563 0.13 ENSDART00000104616
lepr
leptin receptor
chr9_-_13871935 0.13 ENSDART00000146597
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr23_+_9522781 0.12 ENSDART00000136486
osbpl2b
oxysterol binding protein-like 2b
chr10_-_39154594 0.11 ENSDART00000148825
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr12_-_47774807 0.09 ENSDART00000193831
LO017725.1

chr7_+_26545502 0.08 ENSDART00000140528
tnk1
tyrosine kinase, non-receptor, 1
chr11_+_37278457 0.03 ENSDART00000188946
creld1a
cysteine-rich with EGF-like domains 1a
chr9_+_34334156 0.03 ENSDART00000144272
pou2f1b
POU class 2 homeobox 1b
chr13_-_35984530 0.02 ENSDART00000143488
si:ch211-67f13.8
si:ch211-67f13.8

Network of associatons between targets according to the STRING database.

First level regulatory network of pax1a+pax1b_pax9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.3 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 1.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 GO:0043209 myelin sheath(GO:0043209)
0.1 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases