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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pax3a+pax3b

Z-value: 1.20

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Transcription factors associated with pax3a+pax3b

Gene Symbol Gene ID Gene Info
pax3a
ENSDARG00000010192 paired box 3a
pax3b
ENSDARG00000028348 paired box 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax3adr11_v1_chr2_-_47431205_47431205-0.803.6e-05Click!
pax3bdr11_v1_chr15_-_42206890_422068900.734.1e-04Click!

Activity profile of pax3a+pax3b motif

Sorted Z-values of pax3a+pax3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_59348118 6.03 ENSDART00000170901
cyp3a65
cytochrome P450, family 3, subfamily A, polypeptide 65
chr8_-_25247284 5.10 ENSDART00000132697
gnat2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr7_-_24520866 4.11 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr9_+_22080122 3.38 ENSDART00000065956
ENSDART00000136014
crygm2e
crystallin, gamma M2e
chr13_+_1542493 3.33 ENSDART00000181968
CABZ01044281.1

chr18_+_26829086 3.32 ENSDART00000098356
slc28a1
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr12_-_20796430 3.27 ENSDART00000064339
nme2a
NME/NM23 nucleoside diphosphate kinase 2a
chr23_-_6641223 3.17 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr2_-_5502256 3.13 ENSDART00000193037
saga
S-antigen; retina and pineal gland (arrestin) a
chr18_+_43365890 3.07 ENSDART00000173113
si:ch211-129p13.1
si:ch211-129p13.1
chr24_-_7632187 2.91 ENSDART00000041714
atp6v0a1b
ATPase H+ transporting V0 subunit a1b
chr17_+_3128273 2.85 ENSDART00000122453
zgc:136872
zgc:136872
chr9_-_22069364 2.84 ENSDART00000101938
crygm2b
crystallin, gamma M2b
chr2_-_53481912 2.64 ENSDART00000189610
hsd11b1lb
hydroxysteroid (11-beta) dehydrogenase 1-like b
chr3_+_50312422 2.50 ENSDART00000157689
gas7a
growth arrest-specific 7a
chr18_+_907266 2.49 ENSDART00000171729
pkma
pyruvate kinase M1/2a
chr10_+_44903676 2.45 ENSDART00000158553
zgc:114173
zgc:114173
chr13_-_3516473 2.44 ENSDART00000146240
prkn
parkin RBR E3 ubiquitin protein ligase
chr18_+_26829362 2.33 ENSDART00000132728
slc28a1
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr23_-_45504991 2.28 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr23_+_33963619 2.26 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr15_+_19681718 2.21 ENSDART00000164803
si:dkey-4p15.5
si:dkey-4p15.5
chr23_+_40275601 2.19 ENSDART00000076876
fam46ab
family with sequence similarity 46, member Ab
chr23_-_35483163 2.12 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
fbxo25
F-box protein 25
chr22_+_18389271 2.12 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr8_+_48603398 2.05 ENSDART00000074900
zgc:195023
zgc:195023
chr7_+_20344486 1.94 ENSDART00000134004
ENSDART00000139685
ponzr1
plac8 onzin related protein 1
chr3_-_34801041 1.92 ENSDART00000103043
nsfa
N-ethylmaleimide-sensitive factor a
chr12_-_18519822 1.92 ENSDART00000152780
tex2l
testis expressed 2, like
chr11_-_669270 1.88 ENSDART00000172834
pparg
peroxisome proliferator-activated receptor gamma
chr5_-_26950374 1.86 ENSDART00000050542
htra4
HtrA serine peptidase 4
chr5_-_21065094 1.86 ENSDART00000143785
si:dkey-13n15.2
si:dkey-13n15.2
chr7_-_39552314 1.78 ENSDART00000134174
slc22a18
solute carrier family 22, member 18
chr23_-_41651759 1.76 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr18_+_2189211 1.72 ENSDART00000170827
ccpg1
cell cycle progression 1
chr8_-_410728 1.64 ENSDART00000151255
trim36
tripartite motif containing 36
chr11_-_669558 1.61 ENSDART00000173450
pparg
peroxisome proliferator-activated receptor gamma
chr23_+_44611864 1.58 ENSDART00000145905
ENSDART00000132361
eno3
enolase 3, (beta, muscle)
chr23_+_29966466 1.57 ENSDART00000143583
dvl1a
dishevelled segment polarity protein 1a
chr20_+_50852356 1.54 ENSDART00000167517
ENSDART00000168396
gphnb
gephyrin b
chr5_+_22406672 1.54 ENSDART00000141385
si:dkey-27p18.3
si:dkey-27p18.3
chr22_+_18886209 1.51 ENSDART00000144402
fstl3
follistatin-like 3 (secreted glycoprotein)
chr13_-_37653840 1.45 ENSDART00000143806
si:dkey-188i13.11
si:dkey-188i13.11
chr13_-_3351708 1.44 ENSDART00000042875
si:ch73-193i2.2
si:ch73-193i2.2
chr7_+_24520518 1.40 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr2_+_44571200 1.39 ENSDART00000098132
klhl24a
kelch-like family member 24a
chr25_-_13839743 1.34 ENSDART00000158780
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr22_+_8979955 1.30 ENSDART00000144005
si:ch211-213a13.1
si:ch211-213a13.1
chr7_+_71955486 1.27 ENSDART00000189349
CABZ01071171.1
Danio rerio low density lipoprotein receptor-related protein 4 (lrp4), mRNA.
chr2_-_31754292 1.24 ENSDART00000192498
ralyl
RALY RNA binding protein like
chr10_+_16501699 1.22 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr9_-_53920959 1.21 ENSDART00000149618
mid1
midline 1
chr21_-_2287589 1.21 ENSDART00000161554
si:ch73-299h12.4
si:ch73-299h12.4
chr14_+_597532 1.20 ENSDART00000159805
LO018568.2

chr7_+_61764040 1.19 ENSDART00000056745
acox3
acyl-CoA oxidase 3, pristanoyl
chr21_+_10021823 1.18 ENSDART00000163995
herc7
hect domain and RLD 7
chr11_+_769623 1.16 ENSDART00000172972
vgll4b
vestigial-like family member 4b
chr13_+_2908764 1.14 ENSDART00000162362
wu:fj16a03
wu:fj16a03
chr5_-_34185497 1.13 ENSDART00000146321
fibcd1
fibrinogen C domain containing 1
chr5_+_28161079 1.12 ENSDART00000141109
tacr1a
tachykinin receptor 1a
chr8_+_14710542 1.05 ENSDART00000132899
cacna1ea
calcium channel, voltage-dependent, R type, alpha 1E subunit a
chr19_+_4059200 1.04 ENSDART00000161676
ENSDART00000172424
ENSDART00000161804
btr25
bloodthirsty-related gene family, member 25
chr2_+_39618951 1.04 ENSDART00000077108
zgc:136870
zgc:136870
chr24_+_792429 1.04 ENSDART00000082523
impa2
inositol(myo)-1(or 4)-monophosphatase 2
chr19_-_9882821 1.04 ENSDART00000147128
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr14_-_38878356 1.02 ENSDART00000173082
ENSDART00000039788
uqcrq
ubiquinol-cytochrome c reductase, complex III subunit VII
chr8_+_25247245 1.01 ENSDART00000045798
ampd2b
adenosine monophosphate deaminase 2b
chr5_-_42060121 1.01 ENSDART00000148021
ENSDART00000147407
cenpv
centromere protein V
chr20_+_42563618 0.99 ENSDART00000153441
igf2r
insulin-like growth factor 2 receptor
chr22_-_25033105 0.97 ENSDART00000124220
nptxrb
neuronal pentraxin receptor b
chr5_-_26181863 0.93 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr1_-_17803614 0.92 ENSDART00000138475
sorbs2a
sorbin and SH3 domain containing 2a
chr15_+_24588963 0.92 ENSDART00000155075
zgc:198241
zgc:198241
chr23_-_4925131 0.90 ENSDART00000138805
taz
tafazzin
chr8_-_410199 0.89 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr13_-_44997991 0.88 ENSDART00000115360
CR376783.1

chr18_+_9749375 0.88 ENSDART00000184326
CACNA2D1
si:dkey-266j7.2
chr8_+_26410197 0.82 ENSDART00000145836
ENSDART00000053447
ifrd2
interferon-related developmental regulator 2
chr17_-_23674495 0.80 ENSDART00000122209
ptena
phosphatase and tensin homolog A
chr19_+_4139065 0.80 ENSDART00000172524
si:dkey-218f9.10
si:dkey-218f9.10
chr19_+_9033376 0.77 ENSDART00000192298
ENSDART00000052915
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr3_-_5664123 0.75 ENSDART00000145866
si:ch211-106h11.1
si:ch211-106h11.1
chr16_+_9713850 0.75 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr15_+_39096736 0.74 ENSDART00000129511
ENSDART00000014877
robo2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr5_-_42059869 0.72 ENSDART00000193984
cenpv
centromere protein V
chr2_-_4032732 0.72 ENSDART00000158335
rab18b
RAB18B, member RAS oncogene family
chr23_+_45734011 0.70 ENSDART00000062415
CABZ01088025.1

chr22_-_5958066 0.68 ENSDART00000145821
si:rp71-36a1.3
si:rp71-36a1.3
chr21_-_7995994 0.68 ENSDART00000151632
zgc:171965
zgc:171965
chr19_+_31873308 0.68 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
si:dkeyp-34f6.4
chr13_+_35856463 0.67 ENSDART00000171056
ENSDART00000017202
kcnk1b
potassium channel, subfamily K, member 1b
chr16_+_31853919 0.66 ENSDART00000133886
atn1
atrophin 1
chr4_-_4834347 0.66 ENSDART00000141803
coa6
cytochrome c oxidase assembly factor 6
chr19_+_2726819 0.64 ENSDART00000187122
ENSDART00000112414
rapgef5a
Rap guanine nucleotide exchange factor (GEF) 5a
chr10_-_3258073 0.63 ENSDART00000113162
pi4kaa
phosphatidylinositol 4-kinase, catalytic, alpha a
chr13_+_37653851 0.63 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
phf3
PHD finger protein 3
chr7_+_16033273 0.62 ENSDART00000187303
immp1l
inner mitochondrial membrane peptidase subunit 1
chr6_+_37529383 0.60 ENSDART00000039934
ENSDART00000136585
ENSDART00000187756
slc9a7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr25_-_23052707 0.59 ENSDART00000024633
dusp8a
dual specificity phosphatase 8a
chr14_-_21238046 0.58 ENSDART00000129743
si:ch211-175m2.5
si:ch211-175m2.5
chr5_+_8196264 0.57 ENSDART00000174564
ENSDART00000161261
lmbrd2a
LMBR1 domain containing 2a
chr5_+_66353589 0.53 ENSDART00000138246
si:ch211-261c8.5
si:ch211-261c8.5
chr9_+_2507526 0.53 ENSDART00000166579
wipf1a
WAS/WASL interacting protein family, member 1a
chr16_+_21789703 0.52 ENSDART00000153617
trim108
tripartite motif containing 108
chr7_-_69647988 0.51 ENSDART00000169943
LO018231.1

chr15_+_26573676 0.50 ENSDART00000154905
ENSDART00000058514
slc13a5b
solute carrier family 13 (sodium-dependent citrate transporter), member 5b
chr19_-_20162980 0.50 ENSDART00000184605
fam221a
family with sequence similarity 221, member A
chr18_-_46280578 0.48 ENSDART00000131724
pld3
phospholipase D family, member 3
chr5_-_29587351 0.48 ENSDART00000136446
ENSDART00000051434
entpd2a.1
ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 1
chr2_+_18017000 0.47 ENSDART00000186877
BX511224.1

chr6_-_53143667 0.47 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr18_-_5111449 0.46 ENSDART00000046902
pdcd10a
programmed cell death 10a
chr4_-_149334 0.44 ENSDART00000163280
tbk1
TANK-binding kinase 1
chr23_-_5729484 0.43 ENSDART00000000488
tnni1a
troponin I type 1a (skeletal, slow)
chr11_-_6048490 0.43 ENSDART00000066164
plvapb
plasmalemma vesicle associated protein b
chr24_+_7336807 0.41 ENSDART00000137010
kmt2ca
lysine (K)-specific methyltransferase 2Ca
chr25_-_12935065 0.41 ENSDART00000167362
ccl39.7
chemokine (C-C motif) ligand 39, duplicate 7
chr22_-_6941098 0.40 ENSDART00000105864
zgc:171500
zgc:171500
chr16_+_32995882 0.40 ENSDART00000170157
prss35
protease, serine, 35
chr23_+_28092083 0.39 ENSDART00000053958
c1galt1a
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr20_+_46660339 0.38 ENSDART00000016530
adcy3b
adenylate cyclase 3b
chr10_-_320153 0.38 ENSDART00000161493
akt2l
v-akt murine thymoma viral oncogene homolog 2, like
chr16_-_44878245 0.37 ENSDART00000154391
ENSDART00000154925
ENSDART00000154697
arhgap33
Rho GTPase activating protein 33
chr8_+_41647539 0.37 ENSDART00000136492
ENSDART00000138799
ENSDART00000134404
si:ch211-158d24.4
si:ch211-158d24.4
chr7_+_27455321 0.37 ENSDART00000148417
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr8_-_36370552 0.36 ENSDART00000097932
ENSDART00000148323
si:busm1-104n07.3
si:busm1-104n07.3
chr4_+_77076645 0.35 ENSDART00000174346
BX005417.2

chr23_-_18381361 0.34 ENSDART00000016891
hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
chr15_-_25556074 0.33 ENSDART00000124677
mmp20a
matrix metallopeptidase 20a (enamelysin)
chr6_+_34870374 0.32 ENSDART00000149356
il23r
interleukin 23 receptor
chr3_-_10970502 0.32 ENSDART00000127500
CR382337.1

chr25_-_29987839 0.31 ENSDART00000154088
fam19a5b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr16_-_13516745 0.31 ENSDART00000145410
si:dkeyp-69b9.3
si:dkeyp-69b9.3
chr11_+_42587900 0.31 ENSDART00000167529
asb14a
ankyrin repeat and SOCS box containing 14a
chr23_-_12931693 0.27 ENSDART00000122176
BX546500.1

chr5_+_54424592 0.25 ENSDART00000165672
ENSDART00000169531
traf2b
Tnf receptor-associated factor 2b
chr11_-_497680 0.24 ENSDART00000154888
cnbpb
CCHC-type zinc finger, nucleic acid binding protein b
chr25_+_35048945 0.24 ENSDART00000155850
hist1h2ba
histone cluster 1, H2ba
chr14_-_1955257 0.24 ENSDART00000193254
pcdh2g5
protocadherin 2 gamma 5
chr24_+_10202718 0.24 ENSDART00000126668
pou6f2
POU class 6 homeobox 2
chr22_-_6082447 0.22 ENSDART00000159504
ENSDART00000145305
si:dkey-19a16.2
si:dkey-19a16.2
chr22_+_1837448 0.20 ENSDART00000160015
znf1183
zinc finger protein 1183
chr3_-_16010968 0.19 ENSDART00000080672
mrps34
mitochondrial ribosomal protein S34
chr8_+_48848200 0.18 ENSDART00000130673
tp73
tumor protein p73
chr23_+_42304602 0.16 ENSDART00000166004
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr8_+_15239549 0.15 ENSDART00000132216
paox1
polyamine oxidase (exo-N4-amino) 1
chr7_+_20344222 0.15 ENSDART00000141186
ENSDART00000139274
ponzr1
plac8 onzin related protein 1
chr25_-_12935424 0.14 ENSDART00000160217
ccl39.7
chemokine (C-C motif) ligand 39, duplicate 7
chr21_-_38852860 0.14 ENSDART00000166101
tlr22
toll-like receptor 22
chr17_-_3815693 0.13 ENSDART00000161207
PLCB4
phospholipase C beta 4
chr1_-_28607353 0.13 ENSDART00000191210
FO907124.1

chr3_-_8265158 0.11 ENSDART00000171310
cyp2k6
cytochrome P450, family 2, subfamily K, polypeptide 6
chr16_-_28727763 0.09 ENSDART00000149575
dcst1
DC-STAMP domain containing 1
chr12_-_48566778 0.08 ENSDART00000063442
cyp4f3
cytochrome P450, family 4, subfamily F, polypeptide 3
chr19_+_33553586 0.07 ENSDART00000183477
runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr20_-_51697437 0.07 ENSDART00000145391
si:ch211-14a11.2
si:ch211-14a11.2
chr16_+_10841163 0.06 ENSDART00000065467
dedd1
death effector domain-containing 1
chr20_-_52616333 0.06 ENSDART00000138348
ENSDART00000132196
si:ch211-221n20.7
si:ch211-221n20.7
chr2_+_45479841 0.05 ENSDART00000151856
si:ch211-66k16.28
si:ch211-66k16.28
chr2_+_35993404 0.05 ENSDART00000170845
lamc2
laminin, gamma 2
chr22_-_24313301 0.03 ENSDART00000161480
uts2d
urotensin 2 domain containing
chr23_+_2789422 0.03 ENSDART00000156954
plcg1
phospholipase C, gamma 1
chr20_-_52666150 0.03 ENSDART00000146716
ENSDART00000134155
si:ch211-221n20.4
si:ch211-221n20.4
chr23_-_20363261 0.02 ENSDART00000054651
si:rp71-17i16.5
si:rp71-17i16.5
chr11_-_497854 0.02 ENSDART00000104520
cnbpb
CCHC-type zinc finger, nucleic acid binding protein b
chr3_+_32615889 0.01 ENSDART00000028010
unc119.2
unc-119 lipid binding chaperone B homolog 2
chr19_-_3781405 0.01 ENSDART00000170609
btr19
bloodthirsty-related gene family, member 19

Network of associatons between targets according to the STRING database.

First level regulatory network of pax3a+pax3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.5 1.5 GO:0018315 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.5 5.1 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.5 1.9 GO:0048940 Golgi vesicle docking(GO:0048211) anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.4 2.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.4 5.7 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.4 1.1 GO:0071314 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.4 3.2 GO:0006833 water transport(GO:0006833)
0.3 1.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.3 3.1 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 3.5 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.2 1.7 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 2.4 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.2 1.6 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 3.3 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.2 2.9 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2 1.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 1.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 2.1 GO:0061333 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.2 0.5 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 1.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.6 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 1.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.7 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.8 GO:0046471 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.1 1.0 GO:0032264 IMP salvage(GO:0032264)
0.1 1.4 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.3 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.4 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 1.0 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.6 GO:0098659 inorganic cation import into cell(GO:0098659) inorganic ion import into cell(GO:0099587)
0.1 6.3 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.1 0.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 2.5 GO:0006096 glycolytic process(GO:0006096)
0.0 0.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 5.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.2 GO:0035329 hippo signaling(GO:0035329)
0.0 1.2 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.5 GO:0046688 response to copper ion(GO:0046688)
0.0 0.7 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.4 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 1.0 GO:0007041 lysosomal transport(GO:0007041)
0.0 1.3 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 4.1 GO:0016042 lipid catabolic process(GO:0016042)
0.0 0.6 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.6 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 1.0 GO:0070509 calcium ion import(GO:0070509)
0.0 2.5 GO:0030041 actin filament polymerization(GO:0030041)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.4 8.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 2.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.5 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 1.1 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.8 GO:0016586 RSC complex(GO:0016586)
0.1 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.0 GO:0005884 actin filament(GO:0005884)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.9 GO:0005795 Golgi stack(GO:0005795)
0.0 0.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 1.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 1.5 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.4 2.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 1.1 GO:0016496 substance P receptor activity(GO:0016496)
0.4 3.2 GO:0015250 water channel activity(GO:0015250)
0.3 1.0 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 1.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 1.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.0 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 1.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.9 GO:0051117 ATPase binding(GO:0051117)
0.2 5.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 1.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 0.8 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.6 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.5 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 3.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 5.7 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.1 2.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 2.1 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 1.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 6.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 6.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 2.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.6 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 4.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.6 GO:0005109 frizzled binding(GO:0005109)
0.0 2.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.7 GO:0048185 activin binding(GO:0048185)
0.0 4.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.5 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 2.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 3.0 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.1 PID CONE PATHWAY Visual signal transduction: Cones
0.2 3.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 1.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 5.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 3.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport