Project

PRJEB1986: zebrafish developmental stages transcriptome

Navigation
Downloads

Results for pbx1a+pbx1b+pbx2+pbx3a+pbx3b

Z-value: 2.39

Motif logo

logo of

Transcription factors associated with pbx1a+pbx1b+pbx2+pbx3a+pbx3b

Gene Symbol Gene ID Gene Info
pbx3b
ENSDARG00000013615 pre-B-cell leukemia homeobox 3b
pbx2
ENSDARG00000019717 pre-B-cell leukemia homeobox 2
pbx3a
ENSDARG00000089262 pre-B-cell leukemia homeobox 3a
pbx1a
ENSDARG00000100494 pre-B-cell leukemia homeobox 1a
pbx1b
ENSDARG00000101131 pre-B-cell leukemia homeobox 1b
pbx3b
ENSDARG00000110194 pre-B-cell leukemia homeobox 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pbx3bdr11_v1_chr8_-_34065573_340655730.961.2e-10Click!
pbx1adr11_v1_chr2_-_18830722_188307830.888.7e-07Click!
pbx2dr11_v1_chr16_+_48626780_48626780-0.822.1e-05Click!
pbx3adr11_v1_chr5_-_5326010_53260100.788.1e-05Click!
pbx1bdr11_v1_chr6_+_2271559_22715590.691.0e-03Click!

Activity profile of pbx1a+pbx1b+pbx2+pbx3a+pbx3b motif

Sorted Z-values of pbx1a+pbx1b+pbx2+pbx3a+pbx3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22232902 17.32 ENSDART00000101845
crygm2d5
crystallin, gamma M2d5
chr9_-_22135576 11.98 ENSDART00000101902
crygm2d8
crystallin, gamma M2d8
chr9_-_22205682 9.90 ENSDART00000101869
crygm2d12
crystallin, gamma M2d12
chr9_-_22318511 9.90 ENSDART00000129295
crygm2d2
crystallin, gamma M2d2
chr9_-_22240052 9.36 ENSDART00000111109
crygm2d9
crystallin, gamma M2d9
chr9_-_22099536 8.82 ENSDART00000101923
CR391987.1

chr9_-_22092089 8.30 ENSDART00000101928
crygm2d13
crystallin, gamma M2d13
chr24_+_29381946 8.29 ENSDART00000189551
ntng1a
netrin g1a
chr9_-_22135420 8.15 ENSDART00000184959
crygm2d8
crystallin, gamma M2d8
chr3_+_32526799 8.04 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr9_-_22129788 8.00 ENSDART00000124272
ENSDART00000175417
crygm2d8
crystallin, gamma M2d8
chr9_-_22122590 7.91 ENSDART00000108748
ENSDART00000174614
crygm2d9
crystallin, gamma M2d9
chr9_-_22188117 7.89 ENSDART00000132890
crygm2d17
crystallin, gamma M2d17
chr9_-_22272181 7.88 ENSDART00000113174
crygm2d7
crystallin, gamma M2d7
chr8_-_25247284 7.47 ENSDART00000132697
gnat2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr9_-_22147567 7.36 ENSDART00000110941
crygm2d14
crystallin, gamma M2d14
chr9_-_22310919 7.00 ENSDART00000108719
crygm2d10
crystallin, gamma M2d10
chr22_+_20720808 6.79 ENSDART00000171321
si:dkey-211f22.5
si:dkey-211f22.5
chr7_+_49862837 6.74 ENSDART00000174315
slc1a2a
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr9_-_22245572 6.66 ENSDART00000114943
crygm2d4
crystallin, gamma M2d4
chr14_-_52521460 6.40 ENSDART00000172110
GPR151
G protein-coupled receptor 151
chr24_+_29382109 6.38 ENSDART00000184620
ENSDART00000188414
ENSDART00000186132
ENSDART00000191489
ntng1a
netrin g1a
chr3_+_32526263 5.80 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr12_+_15008582 5.74 ENSDART00000003847
mylpfb
myosin light chain, phosphorylatable, fast skeletal muscle b
chr3_-_1190132 5.63 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr20_-_34868814 5.61 ENSDART00000153049
stmn4
stathmin-like 4
chr2_+_39021282 5.11 ENSDART00000056577
RBP1 (1 of many)
si:ch211-119o8.7
chr15_-_12545683 5.00 ENSDART00000162807
scn2b
sodium channel, voltage-gated, type II, beta
chr14_+_46410766 4.74 ENSDART00000032342
anxa5a
annexin A5a
chr14_-_6527010 4.72 ENSDART00000125058
nipsnap3a
nipsnap homolog 3A (C. elegans)
chr19_+_37857936 4.50 ENSDART00000189289
nxph1
neurexophilin 1
chr21_+_30563115 4.30 ENSDART00000028566
si:ch211-200p22.4
si:ch211-200p22.4
chr23_-_30431333 4.29 ENSDART00000146633
camta1a
calmodulin binding transcription activator 1a
chr11_+_24001993 4.28 ENSDART00000168215
chia.2
chitinase, acidic.2
chr18_-_33344 4.27 ENSDART00000129125
pde8a
phosphodiesterase 8A
chr16_+_50100420 4.24 ENSDART00000128167
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr1_-_54947592 4.23 ENSDART00000129710
crtac1a
cartilage acidic protein 1a
chr11_-_101758 4.16 ENSDART00000173015
elmo2
engulfment and cell motility 2
chr12_-_4388704 4.15 ENSDART00000152168
si:ch211-173d10.1
si:ch211-173d10.1
chr13_+_45524475 4.14 ENSDART00000074567
ENSDART00000019113
maco1b
macoilin 1b
chr21_-_39670375 4.04 ENSDART00000151567
sgk494b
uncharacterized serine/threonine-protein kinase SgK494b
chr20_-_20821783 4.02 ENSDART00000152577
ENSDART00000027603
ENSDART00000145601
ckbb
creatine kinase, brain b
chr9_-_22076368 4.02 ENSDART00000128486
crygm2a
crystallin, gamma M2a
chr19_-_9829965 4.00 ENSDART00000136842
ENSDART00000142766
cacng8a
calcium channel, voltage-dependent, gamma subunit 8a
chr6_-_38818582 3.96 ENSDART00000149833
cnga3a
cyclic nucleotide gated channel alpha 3a
chr2_-_30770736 3.91 ENSDART00000131230
rgs20
regulator of G protein signaling 20
chr23_+_5108374 3.90 ENSDART00000114263
zgc:194242
zgc:194242
chr9_-_22345500 3.89 ENSDART00000101802
crygm2f
crystallin, gamma M2f
chr20_-_29420713 3.89 ENSDART00000147464
ryr3
ryanodine receptor 3
chr12_+_15002757 3.87 ENSDART00000135036
mylpfb
myosin light chain, phosphorylatable, fast skeletal muscle b
chr2_-_24996441 3.85 ENSDART00000144795
slc35g2a
solute carrier family 35, member G2a
chr3_-_62380146 3.83 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr23_+_39963599 3.80 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr9_-_22069364 3.80 ENSDART00000101938
crygm2b
crystallin, gamma M2b
chr2_+_33189582 3.80 ENSDART00000145588
ENSDART00000136330
ENSDART00000139295
ENSDART00000086340
rnf220a
ring finger protein 220a
chr6_+_48618512 3.73 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr13_+_28702104 3.71 ENSDART00000135481
si:ch211-67n3.9
si:ch211-67n3.9
chr13_+_50375800 3.65 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr23_+_19590006 3.63 ENSDART00000021231
slmapb
sarcolemma associated protein b
chr20_-_47731768 3.58 ENSDART00000031167
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr6_+_4872883 3.54 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
pcdh9
protocadherin 9
chr14_-_47314011 3.53 ENSDART00000178523
fstl5
follistatin-like 5
chr2_-_19109304 3.52 ENSDART00000168028
si:dkey-225f23.5
si:dkey-225f23.5
chr15_+_16521785 3.51 ENSDART00000062191
galnt17
polypeptide N-acetylgalactosaminyltransferase 17
chr15_+_18863875 3.48 ENSDART00000062603
cadm1b
cell adhesion molecule 1b
chr24_-_2947393 3.47 ENSDART00000166661
ENSDART00000147110
tubb6
tubulin, beta 6 class V
chr20_+_13175379 3.46 ENSDART00000025644
ppp2r5a
protein phosphatase 2, regulatory subunit B', alpha isoform
chr23_+_28582865 3.46 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr12_-_31103187 3.44 ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
ENSDART00000122972
ENSDART00000153068
tcf7l2
transcription factor 7 like 2
chr4_-_5291256 3.34 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr9_-_5046315 3.32 ENSDART00000179087
ENSDART00000109954
nr4a2a
nuclear receptor subfamily 4, group A, member 2a
chr23_+_45579497 3.31 ENSDART00000110381
egr4
early growth response 4
chr18_+_13792490 3.30 ENSDART00000136754
cdh13
cadherin 13, H-cadherin (heart)
chr23_-_30960506 3.28 ENSDART00000142661
osbpl2a
oxysterol binding protein-like 2a
chr6_+_2271559 3.27 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b
chr12_-_14922955 3.25 ENSDART00000002078
neurod2
neurogenic differentiation 2
chr25_+_3326885 3.22 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr22_-_13851297 3.22 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr20_-_805245 3.19 ENSDART00000131825
impg1a
interphotoreceptor matrix proteoglycan 1a
chr16_-_13730152 3.18 ENSDART00000138772
ttyh1
tweety family member 1
chr4_-_27398385 3.18 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr10_-_27046639 3.18 ENSDART00000041841
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr11_-_33919014 3.09 ENSDART00000181203
phka2
phosphorylase kinase, alpha 2 (liver)
chr20_+_28434196 3.06 ENSDART00000034245
dpf3
D4, zinc and double PHD fingers, family 3
chr10_-_35236949 3.05 ENSDART00000145804
ypel2a
yippee-like 2a
chr20_+_29743904 3.04 ENSDART00000146366
ENSDART00000153154
kidins220b
kinase D-interacting substrate 220b
chr24_+_3963684 3.00 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
pfkpa
phosphofructokinase, platelet a
chr21_+_11468934 2.99 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
grin1a
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr9_-_42873700 2.99 ENSDART00000125953
ttn.1
titin, tandem duplicate 1
chr9_-_22023061 2.97 ENSDART00000101952
crygm2c
crystallin, gamma M2c
chr25_+_33849647 2.92 ENSDART00000121449
roraa
RAR-related orphan receptor A, paralog a
chr18_-_16801033 2.88 ENSDART00000100100
admb
adrenomedullin b
chr20_+_23083800 2.86 ENSDART00000132093
usp46
ubiquitin specific peptidase 46
chr13_+_22249636 2.82 ENSDART00000108472
ENSDART00000173123
synpo2la
synaptopodin 2-like a
chr2_-_3678029 2.79 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr4_-_18434924 2.78 ENSDART00000190271
socs2
suppressor of cytokine signaling 2
chr11_+_3005536 2.77 ENSDART00000174539
cpne5b
copine Vb
chr19_-_97159 2.74 ENSDART00000179342
adgrb1b
adhesion G protein-coupled receptor B1b
chr23_+_40275601 2.70 ENSDART00000076876
fam46ab
family with sequence similarity 46, member Ab
chr10_+_25726694 2.70 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr8_-_33114202 2.66 ENSDART00000098840
ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr23_+_40275400 2.66 ENSDART00000184259
fam46ab
family with sequence similarity 46, member Ab
chr25_+_19947096 2.65 ENSDART00000154221
kcna6a
potassium voltage-gated channel, shaker-related, subfamily, member 6 a
chr3_+_13190012 2.64 ENSDART00000179747
ENSDART00000109876
ENSDART00000124824
ENSDART00000130261
sun1
Sad1 and UNC84 domain containing 1
chr21_+_11415224 2.63 ENSDART00000049036
zgc:92275
zgc:92275
chr1_+_32528097 2.62 ENSDART00000128317
nlgn4a
neuroligin 4a
chr4_-_27301356 2.61 ENSDART00000100444
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr11_-_17713987 2.61 ENSDART00000090401
fam19a4b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr19_+_46824723 2.60 ENSDART00000158620
AL953858.1

chr9_-_3149896 2.59 ENSDART00000020861
pdk1
pyruvate dehydrogenase kinase, isozyme 1
chr10_+_5135842 2.58 ENSDART00000132627
ENSDART00000162434
zgc:113274
zgc:113274
chr13_-_37545487 2.54 ENSDART00000131269
syt16
synaptotagmin XVI
chr25_-_19139259 2.54 ENSDART00000067327
abhd2b
abhydrolase domain containing 2b
chr21_-_22635245 2.53 ENSDART00000115224
ENSDART00000101782
nectin1a
nectin cell adhesion molecule 1a
chr17_+_28340138 2.49 ENSDART00000033943
mdga2a
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr23_+_43834376 2.47 ENSDART00000148989
si:ch211-149b19.4
si:ch211-149b19.4
chr14_-_2318590 2.45 ENSDART00000192735
pcdh2ab8
protocadherin 2 alpha b 8
chr5_+_36752943 2.44 ENSDART00000017138
exoc3l2a
exocyst complex component 3-like 2a
chr2_-_7431590 2.44 ENSDART00000185699
asip2b
agouti signaling protein, nonagouti homolog (mouse) 2b
chr14_-_7306983 2.43 ENSDART00000158914
si:ch211-51f19.1
si:ch211-51f19.1
chr24_+_32472155 2.43 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr7_-_38633867 2.42 ENSDART00000137424
c1qtnf4
C1q and TNF related 4
chr1_+_55137943 2.42 ENSDART00000138070
ENSDART00000150510
ENSDART00000133472
ENSDART00000136378
mb
myoglobin
chr3_+_35005062 2.38 ENSDART00000181163
prkcbb
protein kinase C, beta b
chr3_-_62087346 2.38 ENSDART00000092665
srebf1
sterol regulatory element binding transcription factor 1
chr16_+_50434668 2.37 ENSDART00000193500
IGLON5
zgc:110372
chr8_-_44868020 2.37 ENSDART00000142712
cacna1fa
calcium channel, voltage-dependent, L type, alpha 1F subunit a
chr5_-_20678300 2.37 ENSDART00000088639
wscd2
WSC domain containing 2
chr12_-_7824291 2.36 ENSDART00000148673
ENSDART00000149453
ank3b
ankyrin 3b
chr15_-_19250543 2.36 ENSDART00000092705
ENSDART00000138895
igsf9ba
immunoglobulin superfamily, member 9Ba
chr12_-_20350629 2.34 ENSDART00000066384
hbbe2
hemoglobin beta embryonic-2
chr20_+_27646772 2.34 ENSDART00000141697
mthfd1a
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr9_+_27411502 2.28 ENSDART00000143994
si:dkey-193n17.9
si:dkey-193n17.9
chr20_-_44575103 2.26 ENSDART00000192573
ubxn2a
UBX domain protein 2A
chr19_+_8144556 2.24 ENSDART00000027274
ENSDART00000147218
efna3a
ephrin-A3a
chr5_+_9360394 2.23 ENSDART00000124642
FP236810.2

chr7_+_17229980 2.22 ENSDART00000184910
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr25_+_3327071 2.20 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr5_-_13766651 2.20 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr14_+_29609245 2.18 ENSDART00000043058
TENM2
si:dkey-34l15.2
chr9_-_52814204 2.18 ENSDART00000140771
ENSDART00000007401
MAP3K13
si:ch211-45c16.2
chr22_-_23253481 2.18 ENSDART00000054807
lhx9
LIM homeobox 9
chr14_+_45883687 2.16 ENSDART00000114790
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr18_-_51015718 2.16 ENSDART00000190698
LO018598.1

chr9_+_13682133 2.14 ENSDART00000175639
mpp4a
membrane protein, palmitoylated 4a (MAGUK p55 subfamily member 4)
chr22_-_38607504 2.13 ENSDART00000164609
si:ch211-126j24.1
si:ch211-126j24.1
chr2_-_48171112 2.13 ENSDART00000156258
pfkpb
phosphofructokinase, platelet b
chr5_+_68112194 2.12 ENSDART00000162468
CABZ01083937.1

chr16_+_7626535 2.11 ENSDART00000182670
ENSDART00000065514
ENSDART00000150212
stx12l
syntaxin 12, like
chr16_-_563235 2.11 ENSDART00000016303
irx2a
iroquois homeobox 2a
chr22_-_906757 2.11 ENSDART00000193182
FP016205.1

chr10_-_23358357 2.10 ENSDART00000135475
cadm2a
cell adhesion molecule 2a
chr2_-_54039293 2.10 ENSDART00000166013
abhd8a
abhydrolase domain containing 8a
chr5_-_36837846 2.08 ENSDART00000032481
ckma
creatine kinase, muscle a
chr21_-_12119711 2.06 ENSDART00000131538
celf4
CUGBP, Elav-like family member 4
chr4_+_9669717 2.05 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr15_+_3284416 2.04 ENSDART00000187665
ENSDART00000171723
foxo1a
forkhead box O1 a
chr17_-_16324565 2.04 ENSDART00000030835
hmbox1a
homeobox containing 1a
chr1_-_46401385 2.04 ENSDART00000150029
atp11a
ATPase phospholipid transporting 11A
chr11_+_7261981 2.02 ENSDART00000130400
ENSDART00000155427
reep6
receptor accessory protein 6
chr6_+_43903209 2.01 ENSDART00000006435
gpr27
G protein-coupled receptor 27
chr8_+_25247245 2.01 ENSDART00000045798
ampd2b
adenosine monophosphate deaminase 2b
chr18_+_50907675 2.01 ENSDART00000159950
si:ch1073-450f2.1
si:ch1073-450f2.1
chr7_-_71829649 2.00 ENSDART00000160449
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr24_-_14711597 1.99 ENSDART00000131830
jph1a
junctophilin 1a
chr25_+_34862225 1.98 ENSDART00000149782
CHST6
zgc:194879
chr15_-_7598294 1.98 ENSDART00000165898
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr15_-_7598542 1.97 ENSDART00000173092
gbe1b
glucan (1,4-alpha-), branching enzyme 1b
chr22_+_34430310 1.97 ENSDART00000109860
amigo3
adhesion molecule with Ig-like domain 3
chr8_+_23213320 1.97 ENSDART00000032996
ENSDART00000137536
ppdpfa
pancreatic progenitor cell differentiation and proliferation factor a
chr14_+_33458294 1.96 ENSDART00000075278
atp1b4
ATPase Na+/K+ transporting subunit beta 4
chr8_-_410728 1.95 ENSDART00000151255
trim36
tripartite motif containing 36
chr15_+_47746176 1.93 ENSDART00000154481
ENSDART00000160914
stard10
StAR-related lipid transfer (START) domain containing 10
chr3_+_16724614 1.93 ENSDART00000182135
gys1
glycogen synthase 1 (muscle)
chr2_-_51719439 1.91 ENSDART00000170385
tgm1l1
transglutaminase 1 like 1
chr8_+_7144066 1.91 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr5_+_19320554 1.90 ENSDART00000165119
rusc2
RUN and SH3 domain containing 2
chr17_+_33226955 1.90 ENSDART00000063333
pomca
proopiomelanocortin a
chr1_-_26702930 1.90 ENSDART00000109297
ENSDART00000152389
foxe1
forkhead box E1
chr16_+_41873708 1.89 ENSDART00000084631
ENSDART00000084639
ENSDART00000058611
scn1ba
sodium channel, voltage-gated, type I, beta a
chr9_-_7257877 1.86 ENSDART00000153514
si:ch211-121j5.4
si:ch211-121j5.4
chr23_-_18024543 1.85 ENSDART00000139695
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr20_+_661037 1.85 ENSDART00000168271
nrl
neural retina leucine zipper
chr23_+_33963619 1.84 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr20_+_18225329 1.83 ENSDART00000144172
kctd1
potassium channel tetramerization domain containing 1
chr10_+_25369859 1.82 ENSDART00000047541
bach1b
BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
chr2_+_9918935 1.81 ENSDART00000140434
acbd5b
acyl-CoA binding domain containing 5b
chr19_-_12648122 1.81 ENSDART00000151184
fam210aa
family with sequence similarity 210, member Aa
chr23_-_30954738 1.80 ENSDART00000188996
osbpl2a
oxysterol binding protein-like 2a
chr3_-_8199772 1.78 ENSDART00000164614
CABZ01019904.1

chr8_+_13849999 1.78 ENSDART00000143784
doc2d
double C2-like domains, delta
chr12_-_4346085 1.77 ENSDART00000112433
ca15c
carbonic anhydrase XV c
chr22_-_15385442 1.77 ENSDART00000090975
tmem264
transmembrane protein 264
chr3_+_62353650 1.75 ENSDART00000112428
iqck
IQ motif containing K
chr2_+_59015878 1.75 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
si:ch1073-391i24.1
chr1_-_19215336 1.73 ENSDART00000162949
ENSDART00000170680
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr17_+_46387086 1.73 ENSDART00000157079
si:dkey-206p8.1
si:dkey-206p8.1
chr10_+_22724059 1.72 ENSDART00000136123
kdm6bb
lysine (K)-specific demethylase 6B, b
chr12_-_20120702 1.72 ENSDART00000153387
ENSDART00000158412
ENSDART00000112768
ubald1a
UBA-like domain containing 1a
chr7_-_4036184 1.71 ENSDART00000019949
ndrg2
NDRG family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of pbx1a+pbx1b+pbx2+pbx3a+pbx3b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 134.6 GO:0002088 lens development in camera-type eye(GO:0002088)
0.9 3.4 GO:0010226 response to lithium ion(GO:0010226)
0.8 2.5 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.8 2.5 GO:0021611 facial nerve formation(GO:0021611)
0.8 4.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.8 3.3 GO:0060074 synapse maturation(GO:0060074)
0.8 2.4 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.8 3.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.7 7.5 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.7 2.2 GO:0097377 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.7 2.7 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.6 6.8 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.6 1.7 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.5 2.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.5 2.5 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.5 1.5 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.5 3.4 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.5 4.7 GO:0050819 negative regulation of coagulation(GO:0050819)
0.5 6.1 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.5 1.9 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.4 3.3 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.4 7.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.4 1.6 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.4 2.8 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.4 4.3 GO:0006032 chitin catabolic process(GO:0006032)
0.4 3.3 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.4 1.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.3 1.4 GO:0045988 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.3 2.9 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.3 0.9 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.3 2.7 GO:1904861 excitatory synapse assembly(GO:1904861)
0.3 8.3 GO:0070831 basement membrane assembly(GO:0070831)
0.3 1.5 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.3 0.9 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 3.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 2.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.3 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.3 1.0 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.2 4.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.2 3.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 1.4 GO:0003272 endocardial cushion formation(GO:0003272)
0.2 0.7 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 4.8 GO:0015671 oxygen transport(GO:0015671)
0.2 1.1 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.2 1.6 GO:0048745 smooth muscle tissue development(GO:0048745)
0.2 0.9 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 4.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 1.4 GO:0036268 swimming(GO:0036268)
0.2 1.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 0.6 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.2 1.3 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.2 1.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 3.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 6.0 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.2 1.5 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.2 3.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.2 0.5 GO:0033210 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.2 0.5 GO:0003091 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.2 1.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.0 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.1 3.6 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.1 2.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 1.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 1.6 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 4.9 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 2.0 GO:0032264 IMP salvage(GO:0032264)
0.1 4.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 6.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.7 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 3.1 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 2.1 GO:0009584 detection of visible light(GO:0009584)
0.1 1.1 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 1.9 GO:0003417 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.1 1.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 0.6 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.6 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.1 2.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.5 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.3 GO:2000812 positive regulation of protein depolymerization(GO:1901881) regulation of barbed-end actin filament capping(GO:2000812)
0.1 1.6 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 5.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 3.1 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 1.7 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.1 0.8 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 5.0 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 1.0 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.7 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 5.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 3.0 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.7 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 4.3 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 1.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.6 GO:0039014 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.1 1.9 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.9 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.1 2.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.7 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.6 GO:0044211 CTP salvage(GO:0044211)
0.1 1.3 GO:0006265 DNA topological change(GO:0006265)
0.1 0.8 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.2 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 2.5 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.1 2.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.8 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.3 GO:0002027 regulation of heart rate(GO:0002027)
0.1 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 2.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.4 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.1 7.8 GO:0007601 visual perception(GO:0007601)
0.1 2.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.2 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.1 0.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 2.0 GO:0033500 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.1 1.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 5.4 GO:0006909 phagocytosis(GO:0006909)
0.0 2.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 2.8 GO:0070509 calcium ion import(GO:0070509)
0.0 1.1 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 1.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 2.1 GO:0030641 regulation of pH(GO:0006885) regulation of cellular pH(GO:0030641)
0.0 0.5 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.6 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.6 GO:0097324 melanocyte migration(GO:0097324)
0.0 1.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.5 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 1.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 2.0 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.9 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.9 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 1.9 GO:0016358 dendrite development(GO:0016358)
0.0 0.2 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 2.1 GO:0048278 vesicle docking(GO:0048278)
0.0 6.5 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 1.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 5.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.8 GO:0072348 sulfur compound transport(GO:0072348)
0.0 1.9 GO:0006821 chloride transport(GO:0006821)
0.0 0.6 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 1.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.6 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 2.1 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.2 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.9 GO:0061512 protein localization to cilium(GO:0061512)
0.0 1.0 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 1.9 GO:0050769 positive regulation of neurogenesis(GO:0050769)
0.0 0.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.4 GO:0007600 sensory perception(GO:0007600)
0.0 0.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.2 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.4 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.5 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.6 GO:0006936 muscle contraction(GO:0006936)
0.0 0.4 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0060324 face development(GO:0060324)
0.0 0.5 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0044316 cone cell pedicle(GO:0044316)
1.0 7.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.9 3.4 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.7 14.7 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.6 2.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.6 6.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.6 7.3 GO:1990246 uniplex complex(GO:1990246)
0.5 3.2 GO:0070062 extracellular exosome(GO:0070062)
0.5 1.6 GO:0005948 acetolactate synthase complex(GO:0005948)
0.4 1.6 GO:0032584 growth cone membrane(GO:0032584)
0.4 2.0 GO:0030314 junctional membrane complex(GO:0030314)
0.4 3.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.4 4.3 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.4 2.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.3 8.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.3 1.4 GO:0031673 H zone(GO:0031673)
0.3 7.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 1.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.3 3.5 GO:0044295 axonal growth cone(GO:0044295)
0.3 3.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 1.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 1.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 1.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 3.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 2.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 2.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 0.6 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.2 1.5 GO:0033010 paranodal junction(GO:0033010)
0.2 4.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 1.0 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.2 2.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 2.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.7 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.0 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.1 GO:0071565 nBAF complex(GO:0071565)
0.1 1.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 4.0 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.4 GO:0000145 exocyst(GO:0000145)
0.1 4.4 GO:0034704 calcium channel complex(GO:0034704)
0.1 1.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 3.8 GO:0005776 autophagosome(GO:0005776)
0.1 0.6 GO:0032420 stereocilium(GO:0032420)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 2.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.6 GO:0043679 axon terminus(GO:0043679)
0.0 3.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 1.4 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 3.8 GO:0034703 cation channel complex(GO:0034703)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 8.3 GO:0005911 cell-cell junction(GO:0005911)
0.0 1.3 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 3.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 1.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0000407 pre-autophagosomal structure(GO:0000407)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 136.0 GO:0005212 structural constituent of eye lens(GO:0005212)
1.0 3.9 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
1.0 3.9 GO:0008169 C-methyltransferase activity(GO:0008169)
0.8 3.2 GO:0044548 S100 protein binding(GO:0044548)
0.8 3.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.8 5.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.7 3.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.6 6.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.6 3.5 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.5 1.6 GO:0003984 acetolactate synthase activity(GO:0003984)
0.5 2.4 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.5 1.9 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.5 6.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.4 3.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.4 14.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 1.7 GO:0071253 connexin binding(GO:0071253)
0.4 3.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.4 4.3 GO:0004568 chitinase activity(GO:0004568)
0.4 3.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.4 1.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.4 3.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 2.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.3 2.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.3 4.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 2.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 4.0 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.3 1.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 5.8 GO:0035258 steroid hormone receptor binding(GO:0035258)
0.3 1.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 5.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 2.7 GO:0043495 protein anchor(GO:0043495)
0.2 4.8 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.2 0.7 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.2 0.7 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.2 1.3 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 6.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 2.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.2 1.6 GO:0031628 opioid receptor binding(GO:0031628)
0.2 1.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 2.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160) ionotropic glutamate receptor binding(GO:0035255)
0.2 2.0 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 2.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 3.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 4.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 4.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 0.7 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.2 4.5 GO:0015248 sterol transporter activity(GO:0015248)
0.2 1.9 GO:0004046 aminoacylase activity(GO:0004046)
0.2 1.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 2.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 1.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 3.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.0 GO:0070728 leucine binding(GO:0070728)
0.1 4.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.6 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 2.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 1.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.5 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 5.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 5.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 2.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 7.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 3.8 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 2.1 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.3 GO:0030552 cAMP binding(GO:0030552)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.9 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.1 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.9 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.4 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 1.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.2 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 1.1 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 1.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.5 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 2.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.8 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 2.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 6.3 GO:0015293 symporter activity(GO:0015293)
0.0 0.9 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 3.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.7 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.7 GO:0022829 wide pore channel activity(GO:0022829)
0.0 10.3 GO:0051015 actin filament binding(GO:0051015)
0.0 4.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 2.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.3 GO:0005267 potassium channel activity(GO:0005267)
0.0 1.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 5.7 GO:0015631 tubulin binding(GO:0015631)
0.0 1.3 GO:0060090 binding, bridging(GO:0060090)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.5 7.5 PID CONE PATHWAY Visual signal transduction: Cones
0.2 2.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 2.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 3.1 ST ADRENERGIC Adrenergic Pathway
0.1 4.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 1.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 3.4 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.4 3.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 5.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 3.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 3.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 2.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 3.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 3.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 2.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 4.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.9 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 2.2 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 5.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis