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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pdx1_pbx4

Z-value: 0.88

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Transcription factors associated with pdx1_pbx4

Gene Symbol Gene ID Gene Info
pdx1
ENSDARG00000002779 pancreatic and duodenal homeobox 1
pdx1
ENSDARG00000109275 pancreatic and duodenal homeobox 1
pbx4
ENSDARG00000052150 pre-B-cell leukemia transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pbx4dr11_v1_chr3_+_53052769_530527690.253.1e-01Click!
pdx1dr11_v1_chr24_+_21684189_21684189-0.204.1e-01Click!

Activity profile of pdx1_pbx4 motif

Sorted Z-values of pdx1_pbx4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_36243774 5.31 ENSDART00000023323
zgc:172270
zgc:172270
chr12_-_11457625 3.70 ENSDART00000012318
htra1b
HtrA serine peptidase 1b
chr18_+_13792490 3.65 ENSDART00000136754
cdh13
cadherin 13, H-cadherin (heart)
chr24_+_38301080 3.44 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr20_+_1088658 3.05 ENSDART00000162991
BX537249.1

chr14_+_35237613 2.96 ENSDART00000163465
ebf3a
early B cell factor 3a
chr24_-_6898302 2.56 ENSDART00000158646
dpp6a
dipeptidyl-peptidase 6a
chr4_-_16333944 2.01 ENSDART00000079523
epyc
epiphycan
chr1_-_26023678 1.95 ENSDART00000054202
si:ch211-145b13.5
si:ch211-145b13.5
chr12_+_39685485 1.92 ENSDART00000163403
LO017650.1

chr1_+_17676745 1.91 ENSDART00000030665
slc25a4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr24_-_6897884 1.87 ENSDART00000080766
dpp6a
dipeptidyl-peptidase 6a
chr8_+_6954984 1.67 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr7_-_35066457 1.64 ENSDART00000058067
zgc:112160
zgc:112160
chr4_+_21129752 1.63 ENSDART00000169764
syt1a
synaptotagmin Ia
chr15_-_27710513 1.57 ENSDART00000005641
ENSDART00000134373
lhx1a
LIM homeobox 1a
chr23_-_6641223 1.55 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr15_+_4632782 1.54 ENSDART00000156012
si:dkey-35i13.1
si:dkey-35i13.1
chr18_+_783936 1.49 ENSDART00000193357
rpp25b
ribonuclease P and MRP subunit p25, b
chr19_+_37925616 1.48 ENSDART00000148348
nxph1
neurexophilin 1
chr20_-_8443425 1.41 ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr2_+_2223837 1.35 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr21_-_43079161 1.33 ENSDART00000144151
jakmip2
janus kinase and microtubule interacting protein 2
chr5_-_29643930 1.32 ENSDART00000161250
grin1b
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr22_+_3223489 1.29 ENSDART00000082011
lim2.2
lens intrinsic membrane protein 2.2
chr22_+_35068046 1.23 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr16_-_16152199 1.18 ENSDART00000012718
fabp11b
fatty acid binding protein 11b
chr9_+_42066030 1.16 ENSDART00000185311
ENSDART00000015267
pcbp3
poly(rC) binding protein 3
chr10_-_26744131 1.13 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr12_-_26406323 1.12 ENSDART00000131896
myoz1b
myozenin 1b
chr9_-_23217196 1.09 ENSDART00000083567
kif5c
kinesin family member 5C
chr1_-_43963441 1.06 ENSDART00000137646
odam
odontogenic, ameloblast associated
chr19_-_5345930 1.05 ENSDART00000066620
ENSDART00000151398
krtt1c19e
keratin type 1 c19e
chr7_-_8374950 1.03 ENSDART00000057101
aep1
aerolysin-like protein
chr14_-_2199573 1.03 ENSDART00000124485
pcdh2ab8
protocadherin 2 alpha b 8
chr5_-_50992690 1.01 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr12_+_16440708 1.00 ENSDART00000113810
ankrd1b
ankyrin repeat domain 1b (cardiac muscle)
chr19_-_26869103 0.99 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr19_-_10395683 0.98 ENSDART00000109488
zgc:194578
zgc:194578
chr25_+_20215964 0.94 ENSDART00000139235
tnnt2d
troponin T2d, cardiac
chr20_-_29420713 0.92 ENSDART00000147464
ryr3
ryanodine receptor 3
chr4_-_4387012 0.91 ENSDART00000191836
CU468826.3
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr12_+_27213733 0.90 ENSDART00000133048
nbr1a
neighbor of brca1 gene 1a
chr12_+_38770654 0.90 ENSDART00000155367
kif19
kinesin family member 19
chr25_+_15354095 0.89 ENSDART00000090397
kiaa1549la
KIAA1549-like a
chr2_+_42724404 0.89 ENSDART00000075392
basp1
brain abundant, membrane attached signal protein 1
chr7_-_52842007 0.89 ENSDART00000182710
map1aa
microtubule-associated protein 1Aa
chr8_+_22931427 0.89 ENSDART00000063096
sypa
synaptophysin a
chr12_+_9703172 0.88 ENSDART00000091489
ppp1r9bb
protein phosphatase 1, regulatory subunit 9Bb
chr18_-_38088099 0.86 ENSDART00000146120
luzp2
leucine zipper protein 2
chr8_+_44703864 0.85 ENSDART00000016225
star
steroidogenic acute regulatory protein
chr2_-_722156 0.84 ENSDART00000045770
ENSDART00000169498
foxq1a
forkhead box Q1a
chr7_+_46252993 0.83 ENSDART00000167149
znf536
zinc finger protein 536
chr4_-_27301356 0.83 ENSDART00000100444
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr6_-_46875310 0.82 ENSDART00000154442
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr25_+_20216159 0.82 ENSDART00000048642
tnnt2d
troponin T2d, cardiac
chr24_-_40009446 0.82 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr7_-_8417315 0.81 ENSDART00000173046
jac1
jacalin 1
chr5_+_44654535 0.81 ENSDART00000182190
ENSDART00000181872
dapk1
death-associated protein kinase 1
chr16_+_10776688 0.80 ENSDART00000161969
ENSDART00000172657
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr8_-_34052019 0.80 ENSDART00000040126
ENSDART00000159208
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr5_-_51619742 0.79 ENSDART00000188537
otpb
orthopedia homeobox b
chr4_-_5291256 0.78 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr5_-_23280098 0.78 ENSDART00000126540
ENSDART00000051533
plp1b
proteolipid protein 1b
chr4_-_4780667 0.77 ENSDART00000133973
si:ch211-258f14.2
si:ch211-258f14.2
chr3_-_32818607 0.76 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr18_-_42172101 0.75 ENSDART00000124211
cntn5
contactin 5
chr25_-_29363934 0.74 ENSDART00000166889
nptna
neuroplastin a
chr11_-_44030962 0.73 ENSDART00000171910
FP016005.1

chr10_-_39011514 0.70 ENSDART00000075123
pcp4a
Purkinje cell protein 4a
chr1_-_19845378 0.68 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
grhprb
glyoxylate reductase/hydroxypyruvate reductase b
chr3_-_52644737 0.68 ENSDART00000126180
si:dkey-210j14.3
si:dkey-210j14.3
chr9_+_2002701 0.68 ENSDART00000082329
evx2
even-skipped homeobox 2
chr13_+_38302665 0.67 ENSDART00000145777
adgrb3
adhesion G protein-coupled receptor B3
chr7_+_73593814 0.66 ENSDART00000110544
znf219
zinc finger protein 219
chr10_+_439692 0.65 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr21_+_40092301 0.64 ENSDART00000145150
serpinf2a
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr25_-_4482449 0.64 ENSDART00000056278
ENSDART00000149425
slc25a22a
solute carrier family 25 member 22a
chr12_-_20362041 0.64 ENSDART00000184145
ENSDART00000105952
aqp8a.2
aquaporin 8a, tandem duplicate 2
chr12_-_26064480 0.63 ENSDART00000158215
ENSDART00000171206
ENSDART00000171212
ENSDART00000182956
ENSDART00000186779
ldb3b
LIM domain binding 3b
chr1_-_46981134 0.63 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr3_-_20040636 0.62 ENSDART00000104118
atxn7l3
ataxin 7-like 3
chr3_-_16068236 0.62 ENSDART00000157315
si:dkey-81l17.6
si:dkey-81l17.6
chr12_-_28881638 0.60 ENSDART00000148459
ENSDART00000039667
ENSDART00000148668
ENSDART00000136593
ENSDART00000139923
ENSDART00000148912
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr4_-_42408339 0.60 ENSDART00000172612
si:ch211-59d8.3
si:ch211-59d8.3
chr17_-_12385308 0.60 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr23_-_11870962 0.59 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr21_+_30194904 0.59 ENSDART00000137023
ENSDART00000078403
BRD8
si:ch211-59d17.3
chr25_-_30047477 0.59 ENSDART00000164859
CR759810.1

chr25_+_13406069 0.59 ENSDART00000010495
znrf1
zinc and ring finger 1
chr23_+_5490854 0.58 ENSDART00000175403
tulp1a
tubby like protein 1a
chr25_-_7925269 0.58 ENSDART00000014274
glcea
glucuronic acid epimerase a
chr19_-_10243148 0.58 ENSDART00000148073
shisa7b
shisa family member 7
chr20_-_29418620 0.57 ENSDART00000172634
ryr3
ryanodine receptor 3
chr3_+_32862730 0.57 ENSDART00000144939
ENSDART00000125126
ENSDART00000144531
ENSDART00000141717
ENSDART00000137599
zgc:162613
zgc:162613
chr9_-_33725972 0.57 ENSDART00000028225
mao
monoamine oxidase
chr1_-_19215336 0.56 ENSDART00000162949
ENSDART00000170680
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr6_+_40661703 0.55 ENSDART00000142492
eno1b
enolase 1b, (alpha)
chr23_+_4689626 0.55 ENSDART00000131532
gp9
glycoprotein IX (platelet)
chr1_-_681116 0.55 ENSDART00000165894
adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr7_-_13882988 0.55 ENSDART00000169828
rlbp1a
retinaldehyde binding protein 1a
chr13_+_22479988 0.55 ENSDART00000188182
ENSDART00000192972
ENSDART00000178372
ldb3a
LIM domain binding 3a
chr4_+_26496489 0.54 ENSDART00000160652
iqsec3a
IQ motif and Sec7 domain 3a
chr19_+_4443285 0.54 ENSDART00000162683
trappc9
trafficking protein particle complex 9
chr12_+_48634927 0.54 ENSDART00000168441
zgc:165653
zgc:165653
chr2_+_7818368 0.54 ENSDART00000007068
kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr18_+_41495841 0.54 ENSDART00000098671
si:ch211-203b8.6
si:ch211-203b8.6
chr24_-_24881996 0.54 ENSDART00000145712
crhb
corticotropin releasing hormone b
chr23_+_40460333 0.54 ENSDART00000184658
soga3b
SOGA family member 3b
chr16_-_28658341 0.53 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr4_+_40427249 0.53 ENSDART00000151927
si:ch211-218h8.3
si:ch211-218h8.3
chr24_+_32472155 0.53 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr25_-_7925019 0.53 ENSDART00000183309
glcea
glucuronic acid epimerase a
chr8_+_21376290 0.52 ENSDART00000136765
ela2
elastase 2
chr21_-_27338639 0.52 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr17_+_23937262 0.52 ENSDART00000113276
si:ch211-189k9.2
si:ch211-189k9.2
chr4_+_13810811 0.50 ENSDART00000067168
pdzrn4
PDZ domain containing ring finger 4
chr18_-_36135799 0.50 ENSDART00000059344
b3gat1a
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr16_+_46453176 0.49 ENSDART00000132793
rpz3
rapunzel 3
chr23_+_28322986 0.49 ENSDART00000134710
birc5b
baculoviral IAP repeat containing 5b
chr17_+_9308425 0.49 ENSDART00000188283
ENSDART00000183311
NPAS3
neuronal PAS domain protein 3
chr22_-_33679277 0.49 ENSDART00000169948
FO904977.1

chr8_+_21406769 0.48 ENSDART00000135766
si:dkey-163f12.6
si:dkey-163f12.6
chr6_+_4872883 0.48 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
pcdh9
protocadherin 9
chr1_-_23557877 0.48 ENSDART00000145942
fam184b
family with sequence similarity 184, member B
chr4_+_7391110 0.47 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr13_-_33000649 0.47 ENSDART00000133677
rbm25a
RNA binding motif protein 25a
chr4_-_60314809 0.46 ENSDART00000164606
si:dkey-248e17.4
si:dkey-248e17.4
chr13_+_22480496 0.46 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr2_-_10188598 0.46 ENSDART00000189122
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr6_+_45347219 0.46 ENSDART00000188240
LO017951.1

chr18_-_20466061 0.46 ENSDART00000060311
paqr5a
progestin and adipoQ receptor family member Va
chr1_-_26294995 0.46 ENSDART00000168594
cxxc4
CXXC finger 4
chr8_+_23165749 0.46 ENSDART00000063057
dnajc5aa
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr13_+_50375800 0.46 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr17_-_16133249 0.45 ENSDART00000030919
pnoca
prepronociceptin a
chr14_+_36231126 0.45 ENSDART00000141766
elovl6
ELOVL fatty acid elongase 6
chr2_+_45068366 0.44 ENSDART00000142175
si:dkey-76d14.2
si:dkey-76d14.2
chr7_+_29952719 0.44 ENSDART00000173737
tpma
alpha-tropomyosin
chr9_-_22834860 0.43 ENSDART00000146486
neb
nebulin
chr14_+_3495542 0.43 ENSDART00000168934
gstp2
glutathione S-transferase pi 2
chr21_+_5518619 0.43 ENSDART00000170587
ly6m5
lymphocyte antigen 6 family member M5
chr6_+_45346808 0.43 ENSDART00000186327
LO017951.1

chr8_+_38415374 0.42 ENSDART00000085395
nkx6.3
NK6 homeobox 3
chr8_+_44420108 0.42 ENSDART00000075381
CU571323.1

chr13_+_22249636 0.41 ENSDART00000108472
ENSDART00000173123
synpo2la
synaptopodin 2-like a
chr17_+_19626479 0.41 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr14_-_4044545 0.41 ENSDART00000169527
snx25
sorting nexin 25
chr20_+_4793790 0.41 ENSDART00000153486
lgals8a
galectin 8a
chr2_+_26647472 0.41 ENSDART00000145415
ENSDART00000157409
ttpa
tocopherol (alpha) transfer protein
chr5_+_9382301 0.41 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr3_-_59981476 0.40 ENSDART00000035878
ENSDART00000124038
cdr2l
cerebellar degeneration-related protein 2-like
chr25_-_13842618 0.40 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr6_-_47246948 0.40 ENSDART00000162435
grm4
glutamate receptor, metabotropic 4
chr12_-_31009315 0.40 ENSDART00000133854
tcf7l2
transcription factor 7 like 2
chr11_-_17713987 0.40 ENSDART00000090401
fam19a4b
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr1_-_40227166 0.40 ENSDART00000146680
si:ch211-113e8.3
si:ch211-113e8.3
chr2_+_25657958 0.39 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr2_-_18830722 0.39 ENSDART00000165330
ENSDART00000165698
pbx1a
pre-B-cell leukemia homeobox 1a
chr23_+_216012 0.39 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
PDZD4
si:ch73-162j3.4
chr17_-_6399920 0.39 ENSDART00000022010
hivep2b
human immunodeficiency virus type I enhancer binding protein 2b
chr7_-_8408014 0.39 ENSDART00000112492
zgc:194686
zgc:194686
chr14_+_34547554 0.39 ENSDART00000074819
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr7_+_26629084 0.39 ENSDART00000101044
ENSDART00000173765
hsbp1a
heat shock factor binding protein 1a
chr15_+_30917282 0.38 ENSDART00000129474
omgb
oligodendrocyte myelin glycoprotein b
chr1_-_46984142 0.37 ENSDART00000125032
pknox1.2
pbx/knotted 1 homeobox 1.2
chr11_+_24002503 0.37 ENSDART00000164702
chia.2
chitinase, acidic.2
chr17_+_39242437 0.37 ENSDART00000156138
ENSDART00000128863
zgc:174356
zgc:174356
chr6_-_53143667 0.37 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr2_-_716426 0.36 ENSDART00000028159
foxf2a
forkhead box F2a
chr13_+_23282549 0.36 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr17_-_49800869 0.36 ENSDART00000156264
col12a1a
collagen, type XII, alpha 1a
chr17_-_30666037 0.36 ENSDART00000156509
alkal2b
ALK and LTK ligand 2b
chr10_+_21511495 0.36 ENSDART00000178395
BX957322.3

chr24_-_22533959 0.36 ENSDART00000148197
ctnnd2a
catenin (cadherin-associated protein), delta 2a
chr21_+_25181003 0.35 ENSDART00000169700
si:dkey-183i3.9
si:dkey-183i3.9
chr17_-_26507289 0.35 ENSDART00000155616
ccser2a
coiled-coil serine-rich protein 2a
chr10_+_26571174 0.35 ENSDART00000148617
ENSDART00000112956
slc9a6b
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr6_-_49510553 0.35 ENSDART00000166238
rplp2
ribosomal protein, large P2
chr14_-_45702721 0.35 ENSDART00000165727
si:dkey-226n24.1
si:dkey-226n24.1
chr1_+_9144958 0.35 ENSDART00000046507
rasd3
RASD family member 3
chr1_+_47165842 0.35 ENSDART00000053152
ENSDART00000167051
cbr1
carbonyl reductase 1
chr4_-_75678082 0.35 ENSDART00000180201
si:dkey-165o8.1
si:dkey-165o8.1
chr2_+_53357953 0.34 ENSDART00000187577
celf5b
cugbp, Elav-like family member 5b
chr6_-_15641686 0.34 ENSDART00000135583
mlpha
melanophilin a
chr4_+_13640903 0.34 ENSDART00000155349
pnpla8
patatin-like phospholipase domain containing 8
chr10_-_17745345 0.34 ENSDART00000132690
ENSDART00000135376
si:dkey-200l5.4
si:dkey-200l5.4
chr19_+_25478203 0.34 ENSDART00000132934
col28a1a
collagen, type XXVIII, alpha 1a
chr9_-_44939104 0.34 ENSDART00000192903
vil1
villin 1
chr14_+_51056605 0.34 ENSDART00000159639
CABZ01078593.1

chr8_-_39903803 0.33 ENSDART00000012391
cabp1a
calcium binding protein 1a
chr22_-_16180849 0.33 ENSDART00000090390
vcam1b
vascular cell adhesion molecule 1b
chr7_+_35229805 0.33 ENSDART00000173911
tppp3
tubulin polymerization-promoting protein family member 3
chr23_-_21515182 0.33 ENSDART00000142000
rnf207b
ring finger protein 207b
chr13_+_24750078 0.33 ENSDART00000021053
col17a1b
collagen, type XVII, alpha 1b
chr24_+_26402110 0.33 ENSDART00000133684
si:ch211-230g15.5
si:ch211-230g15.5
chr2_+_5948534 0.33 ENSDART00000124324
ENSDART00000176461
slc1a7a
solute carrier family 1 (glutamate transporter), member 7a
chr2_+_37480669 0.32 ENSDART00000029801
sppl2
signal peptide peptidase-like 2
chr11_-_6048490 0.32 ENSDART00000066164
plvapb
plasmalemma vesicle associated protein b
chr5_+_9377005 0.32 ENSDART00000124924
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7

Network of associatons between targets according to the STRING database.

First level regulatory network of pdx1_pbx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.3 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.5 1.6 GO:0090184 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.5 1.9 GO:0015867 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.5 3.6 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.2 1.4 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.2 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.2 1.6 GO:0006833 water transport(GO:0006833)
0.2 1.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 0.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 0.8 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 4.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 0.8 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 0.7 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.8 GO:0021767 mammillary body development(GO:0021767)
0.1 1.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0010226 response to lithium ion(GO:0010226)
0.1 1.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:1990416 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.5 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 0.3 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.3 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 1.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 1.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.6 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.6 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.7 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.4 GO:0070376 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.1 0.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.0 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.1 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.2 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.5 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 1.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.0 0.2 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.3 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.8 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.2 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.4 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.8 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.6 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 1.6 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.9 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.4 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 1.0 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.3 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 1.0 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.6 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 1.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0006775 fat-soluble vitamin metabolic process(GO:0006775)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.4 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.5 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.1 GO:0010991 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.6 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.4 GO:0036294 cellular response to decreased oxygen levels(GO:0036294) cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0048899 anterior lateral line development(GO:0048899)
0.0 0.1 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.0 0.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394) energy homeostasis(GO:0097009)
0.0 0.3 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198) axon midline choice point recognition(GO:0016199)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507) tolerance induction to self antigen(GO:0002513) regulation of platelet activation(GO:0010543) regulation of platelet aggregation(GO:0090330)
0.0 0.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0099587 inorganic cation import into cell(GO:0098659) inorganic ion import into cell(GO:0099587)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.1 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.3 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 1.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 5.3 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.4 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.3 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0032433 filopodium tip(GO:0032433)
0.1 5.0 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.0 2.8 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.0 GO:0046930 pore complex(GO:0046930)
0.0 0.8 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.7 GO:0030426 growth cone(GO:0030426)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.4 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.3 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.0 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0043679 axon terminus(GO:0043679)
0.0 1.1 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 1.4 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.4 1.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.0 GO:0048030 disaccharide binding(GO:0048030)
0.3 1.5 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.3 1.1 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.3 1.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 4.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 2.2 GO:0015250 water channel activity(GO:0015250)
0.2 0.7 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 0.5 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.2 1.8 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 3.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.1 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.3 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.6 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.4 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0019809 spermidine binding(GO:0019809)
0.0 0.2 GO:0031781 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.4 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 1.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 3.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 3.7 GO:0060090 binding, bridging(GO:0060090)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.1 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.0 GO:0050661 NADP binding(GO:0050661)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.9 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0047192 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.0 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport