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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pgr

Z-value: 0.69

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Transcription factors associated with pgr

Gene Symbol Gene ID Gene Info
pgr
ENSDARG00000035966 progesterone receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pgrdr11_v1_chr18_+_41820039_418200390.371.2e-01Click!

Activity profile of pgr motif

Sorted Z-values of pgr motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_59348118 3.04 ENSDART00000170901
cyp3a65
cytochrome P450, family 3, subfamily A, polypeptide 65
chr9_-_22272181 2.23 ENSDART00000113174
crygm2d7
crystallin, gamma M2d7
chr21_+_25187210 2.16 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
si:dkey-183i3.5
chr1_+_51615672 1.91 ENSDART00000165117
zgc:165656
zgc:165656
chr17_-_6730247 1.90 ENSDART00000031091
vsnl1b
visinin-like 1b
chr1_+_7538909 1.88 ENSDART00000148276
mylz3
myosin, light polypeptide 3, skeletal muscle
chr3_+_16612574 1.81 ENSDART00000104481
slc17a7a
solute carrier family 17 (vesicular glutamate transporter), member 7a
chr24_-_27473771 1.78 ENSDART00000139874
cxl34b.11
CX chemokine ligand 34b, duplicate 11
chr5_+_45677781 1.72 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr9_-_43001898 1.70 ENSDART00000138515
ttn.2
titin, tandem duplicate 2
chr18_+_38908903 1.61 ENSDART00000159834
myo5aa
myosin VAa
chr19_-_29437108 1.43 ENSDART00000052108
ENSDART00000074497
fndc5b
fibronectin type III domain containing 5b
chr12_-_3237561 1.39 ENSDART00000164665
si:ch1073-13h15.3
si:ch1073-13h15.3
chr22_-_278328 1.35 ENSDART00000098072
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr7_+_39389273 1.35 ENSDART00000191298
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr3_-_28048475 1.34 ENSDART00000150888
rbfox1
RNA binding fox-1 homolog 1
chr7_+_2467057 1.34 ENSDART00000154517
si:dkey-125e8.3
si:dkey-125e8.3
chr2_+_10134345 1.28 ENSDART00000100725
ahsg2
alpha-2-HS-glycoprotein 2
chr20_-_8419057 1.26 ENSDART00000145841
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr20_+_30445971 1.22 ENSDART00000153150
myt1la
myelin transcription factor 1-like, a
chr24_+_3307857 1.21 ENSDART00000106527
gyg1b
glycogenin 1b
chr6_+_41096058 1.20 ENSDART00000028373
fkbp5
FK506 binding protein 5
chr3_+_34220194 1.20 ENSDART00000145859
slc25a23b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23b
chr21_+_25643880 1.20 ENSDART00000192392
ENSDART00000145091
tmem151a
transmembrane protein 151A
chr2_+_47582488 1.15 ENSDART00000149967
scg2b
secretogranin II (chromogranin C), b
chr11_-_1024483 1.15 ENSDART00000017551
slc6a1b
solute carrier family 6 (neurotransmitter transporter), member 1b
chr5_+_13472234 1.15 ENSDART00000114069
ENSDART00000132406
cnnm4b
cyclin and CBS domain divalent metal cation transport mediator 4b
chr10_-_22249444 1.11 ENSDART00000148831
fgf11b
fibroblast growth factor 11b
chr12_-_4028079 1.10 ENSDART00000128676
si:ch211-180a12.2
si:ch211-180a12.2
chr21_-_10446405 1.10 ENSDART00000167948
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr10_+_21786656 1.10 ENSDART00000185851
ENSDART00000167219
pcdh1g26
protocadherin 1 gamma 26
chr1_+_51896147 1.10 ENSDART00000167139
nfixa
nuclear factor I/Xa
chr11_+_13223625 1.10 ENSDART00000161275
abcb11b
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr2_+_52232630 1.09 ENSDART00000006216
plpp2a
phospholipid phosphatase 2a
chr5_+_51102010 1.05 ENSDART00000110377
zgc:194398
zgc:194398
chr10_+_375042 1.04 ENSDART00000171854
si:ch1073-303d10.1
si:ch1073-303d10.1
chr11_-_33919014 1.04 ENSDART00000181203
phka2
phosphorylase kinase, alpha 2 (liver)
chr7_-_33868903 1.03 ENSDART00000173500
ENSDART00000178746
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr19_+_9344171 1.03 ENSDART00000133447
ENSDART00000104622
si:ch211-288g17.4
si:ch211-288g17.4
chr5_+_30680804 1.03 ENSDART00000078049
pdzd3b
PDZ domain containing 3b
chr21_-_26089964 1.01 ENSDART00000027848
tlcd1
TLC domain containing 1
chr6_-_27139396 1.01 ENSDART00000055848
zgc:103559
zgc:103559
chr8_-_14050758 0.99 ENSDART00000133922
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr18_+_8805575 0.99 ENSDART00000137098
impdh1a
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr25_-_210730 0.98 ENSDART00000187580
FP236318.1

chr8_-_10045043 0.94 ENSDART00000081917
si:dkey-8e10.3
si:dkey-8e10.3
chr23_-_45504991 0.94 ENSDART00000148761
col24a1
collagen type XXIV alpha 1
chr5_+_62356304 0.94 ENSDART00000148381
aspa
aspartoacylase
chr25_+_31277415 0.92 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr8_+_30780985 0.90 ENSDART00000193971
ENSDART00000111533
tas2r200.2
taste receptor, type 2, member 200, tandem duplicate 2
chr3_+_16449490 0.90 ENSDART00000141467
kcnj12b
potassium inwardly-rectifying channel, subfamily J, member 12b
chr7_-_71486162 0.90 ENSDART00000045253
aco1
aconitase 1, soluble
chr3_-_11922713 0.90 ENSDART00000150575
coro7
coronin 7
chr15_+_32710300 0.89 ENSDART00000167857
postnb
periostin, osteoblast specific factor b
chr9_-_41277347 0.88 ENSDART00000181213
glsb
glutaminase b
chr5_-_25174420 0.88 ENSDART00000141554
abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr11_+_13224281 0.87 ENSDART00000102557
ENSDART00000178706
abcb11b
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr1_+_56229674 0.86 ENSDART00000127714
c3a.2
complement component c3a, duplicate 2
chr8_+_53452681 0.86 ENSDART00000166705
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr6_+_11250033 0.85 ENSDART00000065411
ENSDART00000132677
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr15_+_12030367 0.84 ENSDART00000176178
FO904901.1

chr17_+_36627099 0.84 ENSDART00000154104
impg1b
interphotoreceptor matrix proteoglycan 1b
chr18_-_46063773 0.83 ENSDART00000078561
si:ch73-262h23.4
si:ch73-262h23.4
chr20_+_18580176 0.83 ENSDART00000185310
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr14_-_2187202 0.83 ENSDART00000160205
pcdh2ab12
protocadherin 2 alpha b 12
chr6_-_1865323 0.83 ENSDART00000155775
dlgap4b
discs, large (Drosophila) homolog-associated protein 4b
chr11_+_21910343 0.82 ENSDART00000161485
foxp4
forkhead box P4
chr2_+_47581997 0.82 ENSDART00000112579
scg2b
secretogranin II (chromogranin C), b
chr11_+_21076872 0.81 ENSDART00000155521
prelp
proline/arginine-rich end leucine-rich repeat protein
chr5_-_32308526 0.81 ENSDART00000193758
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr7_+_73780936 0.80 ENSDART00000092691
pea15
proliferation and apoptosis adaptor protein 15
chr15_+_37197494 0.80 ENSDART00000166203
aplp1
amyloid beta (A4) precursor-like protein 1
chr13_-_44285793 0.79 ENSDART00000167383
CABZ01069436.1

chr14_-_2209742 0.78 ENSDART00000054889
pcdh2ab5
protocadherin 2 alpha b 5
chr15_+_47386939 0.77 ENSDART00000128224
FO904873.1

chr7_-_2163361 0.76 ENSDART00000173654
si:cabz01007812.1
si:cabz01007812.1
chr13_-_23264724 0.74 ENSDART00000051886
si:dkey-103j14.5
si:dkey-103j14.5
chr20_+_43942278 0.73 ENSDART00000100571
clic5b
chloride intracellular channel 5b
chr5_-_37116265 0.73 ENSDART00000057613
il13ra2
interleukin 13 receptor, alpha 2
chr15_+_28482862 0.73 ENSDART00000015286
ENSDART00000154320
ankrd13b
ankyrin repeat domain 13B
chr4_+_74551606 0.72 ENSDART00000174339
kcna1b
potassium voltage-gated channel, shaker-related subfamily, member 1b
chr15_-_24869826 0.72 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr15_-_163586 0.72 ENSDART00000163597
SEPT4
septin-4
chr25_-_19090479 0.71 ENSDART00000027465
ENSDART00000177670
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr10_+_44146287 0.71 ENSDART00000162176
grk3
G protein-coupled receptor kinase 3
chr8_+_68864 0.71 ENSDART00000164574
prr16
proline rich 16
chr2_-_3678029 0.70 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr6_-_60031693 0.70 ENSDART00000160275
CABZ01079262.1

chr7_+_25033924 0.70 ENSDART00000170873
sb:cb1058
sb:cb1058
chr9_-_22831836 0.70 ENSDART00000142585
neb
nebulin
chr5_+_11812089 0.69 ENSDART00000111359
fbxo21
F-box protein 21
chr12_+_23875318 0.68 ENSDART00000152869
svila
supervillin a
chr14_-_2050057 0.66 ENSDART00000112875
PCDHB15
protocadherin beta 15
chr14_-_2193248 0.65 ENSDART00000128659
pcdh2ab10
protocadherin 2 alpha b 10
chr20_+_33532296 0.65 ENSDART00000153153
kcnf1a
potassium voltage-gated channel, subfamily F, member 1a
chr2_+_47582681 0.65 ENSDART00000187579
scg2b
secretogranin II (chromogranin C), b
chr1_-_22687913 0.65 ENSDART00000168171
fgfbp2b
fibroblast growth factor binding protein 2b
chr5_+_69981453 0.65 ENSDART00000143860
si:ch211-154e10.1
si:ch211-154e10.1
chr15_+_44472356 0.65 ENSDART00000155763
ENSDART00000028011
msantd4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr2_-_24996441 0.64 ENSDART00000144795
slc35g2a
solute carrier family 35, member G2a
chr20_+_29587995 0.64 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr25_+_4541211 0.64 ENSDART00000129978
pnpla2
patatin-like phospholipase domain containing 2
chr20_+_23185530 0.63 ENSDART00000142346
lrrc66
leucine rich repeat containing 66
chr1_-_51615437 0.63 ENSDART00000152185
ENSDART00000152237
ENSDART00000129052
ENSDART00000152595
FBXO48
si:dkey-202b17.4
chr20_-_35706379 0.63 ENSDART00000152847
si:dkey-30j22.1
si:dkey-30j22.1
chr10_-_28519505 0.63 ENSDART00000137964
bbx
bobby sox homolog (Drosophila)
chr5_-_28029558 0.61 ENSDART00000078649
abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr20_+_16750177 0.61 ENSDART00000185357
calm1b
calmodulin 1b
chr6_-_20707846 0.61 ENSDART00000169836
col18a1b
collagen type XVIII alpha 1 chain b
chr7_+_25036188 0.61 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr1_+_51615506 0.61 ENSDART00000152767
zgc:165656
zgc:165656
chr2_+_55916911 0.60 ENSDART00000189483
ENSDART00000183647
ENSDART00000083470
atcayb
ataxia, cerebellar, Cayman type b
chr18_-_10995410 0.60 ENSDART00000136751
tspan33b
tetraspanin 33b
chr8_+_9715010 0.60 ENSDART00000139414
gripap1
GRIP1 associated protein 1
chr16_-_36099492 0.59 ENSDART00000180905
CU499336.2

chr2_+_44571200 0.58 ENSDART00000098132
klhl24a
kelch-like family member 24a
chr21_-_14803554 0.58 ENSDART00000121853
si:dkey-11o18.5
si:dkey-11o18.5
chr18_-_16179129 0.58 ENSDART00000125353
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr9_+_31752628 0.58 ENSDART00000060054
itgbl1
integrin, beta-like 1
chr2_-_36932253 0.58 ENSDART00000124217
map1sb
microtubule-associated protein 1Sb
chr13_-_25719628 0.57 ENSDART00000135383
si:dkey-192p21.6
si:dkey-192p21.6
chr6_-_40429411 0.57 ENSDART00000156005
ENSDART00000156357
si:dkey-28n18.9
si:dkey-28n18.9
chr24_+_32592748 0.57 ENSDART00000188256
si:ch211-282b22.1
si:ch211-282b22.1
chr7_-_66864756 0.57 ENSDART00000184462
ENSDART00000189424
ampd3a
adenosine monophosphate deaminase 3a
chr1_+_33969015 0.57 ENSDART00000042984
ENSDART00000146530
epha6
eph receptor A6
chr18_-_341489 0.57 ENSDART00000168333
si:ch1073-83b15.1
si:ch1073-83b15.1
chr2_-_24603325 0.56 ENSDART00000113356
crtc1a
CREB regulated transcription coactivator 1a
chr9_-_42871756 0.56 ENSDART00000191396
ttn.1
titin, tandem duplicate 1
chr10_+_29199172 0.56 ENSDART00000148828
picalma
phosphatidylinositol binding clathrin assembly protein a
chr22_-_968484 0.56 ENSDART00000105895
cacna1sa
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr7_+_61764040 0.56 ENSDART00000056745
acox3
acyl-CoA oxidase 3, pristanoyl
chr15_+_32710094 0.56 ENSDART00000159592
postnb
periostin, osteoblast specific factor b
chr6_+_11249706 0.55 ENSDART00000186547
ENSDART00000193287
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr7_-_51953613 0.54 ENSDART00000142042
cyp2x10.2
cytochrome P450, family 2, subfamily X, polypeptide 10.2
chr15_+_15316326 0.54 ENSDART00000125864
camkk1b
calcium/calmodulin-dependent protein kinase kinase 1, alpha b
chr9_+_34127005 0.54 ENSDART00000167384
ENSDART00000078065
f5
coagulation factor V
chr11_+_35364445 0.54 ENSDART00000125766
camkvb
CaM kinase-like vesicle-associated b
chr10_+_21722892 0.53 ENSDART00000162855
pcdh1g13
protocadherin 1 gamma 13
chr7_+_56253914 0.53 ENSDART00000073594
ankrd11
ankyrin repeat domain 11
chr8_-_42677086 0.53 ENSDART00000191173
si:ch73-138n13.1
si:ch73-138n13.1
chr11_-_28911172 0.53 ENSDART00000168493
igsf21a
immunoglobin superfamily, member 21a
chr20_-_27857676 0.53 ENSDART00000192934
syndig1l
synapse differentiation inducing 1-like
chr6_+_40874206 0.52 ENSDART00000004295
zgc:112163
zgc:112163
chr25_-_207214 0.52 ENSDART00000193448
FP236318.3

chr19_-_9867001 0.52 ENSDART00000091695
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr7_+_30823749 0.52 ENSDART00000085661
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr7_+_27977065 0.51 ENSDART00000089574
tub
tubby bipartite transcription factor
chr3_+_49397115 0.51 ENSDART00000176042
tecra
trans-2,3-enoyl-CoA reductase a
chr5_-_71460556 0.51 ENSDART00000108804
brinp1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr6_+_41099787 0.51 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr18_+_1145571 0.51 ENSDART00000135055
rec114
REC114 meiotic recombination protein
chr17_-_465285 0.51 ENSDART00000168718
chrm5a
cholinergic receptor, muscarinic 5a
chr21_+_18353703 0.50 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
si:ch73-287m6.1
chr6_-_18400548 0.49 ENSDART00000179797
ENSDART00000164891
trim25
tripartite motif containing 25
chr4_-_14328997 0.49 ENSDART00000091151
nell2b
neural EGFL like 2b
chr17_-_26507289 0.49 ENSDART00000155616
ccser2a
coiled-coil serine-rich protein 2a
chr8_-_36475328 0.49 ENSDART00000048448
si:busm1-266f07.2
si:busm1-266f07.2
chr16_+_16933002 0.48 ENSDART00000173163
myh14
myosin, heavy chain 14, non-muscle
chr2_-_55337585 0.48 ENSDART00000177924
tpm4b
tropomyosin 4b
chr4_-_16333944 0.47 ENSDART00000079523
epyc
epiphycan
chr1_+_58456494 0.47 ENSDART00000164130
si:ch73-236c18.5
si:ch73-236c18.5
chr3_+_22935183 0.47 ENSDART00000157378
hdac5
histone deacetylase 5
chr4_-_20181964 0.47 ENSDART00000022539
fgl2a
fibrinogen-like 2a
chr21_+_25221940 0.47 ENSDART00000108972
sycn.1
syncollin, tandem duplicate 1
chr21_-_22737228 0.46 ENSDART00000151366
fbxo40.2
F-box protein 40, tandem duplicate 2
chr13_+_38430466 0.46 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr4_+_3980247 0.46 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr12_-_41684729 0.46 ENSDART00000184461
jakmip3
Janus kinase and microtubule interacting protein 3
chr1_-_17803614 0.46 ENSDART00000138475
sorbs2a
sorbin and SH3 domain containing 2a
chr17_+_25677458 0.45 ENSDART00000029703
kcnh1a
potassium voltage-gated channel, subfamily H (eag-related), member 1a
chr8_+_36803415 0.45 ENSDART00000111680
iqsec2b
IQ motif and Sec7 domain 2b
chr1_-_65017 0.45 ENSDART00000168609
si:zfos-1011f11.2
si:zfos-1011f11.2
chr7_+_17229980 0.45 ENSDART00000184910
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr5_+_52706316 0.44 ENSDART00000169488
apba1a
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr3_-_42981739 0.44 ENSDART00000167844
mafk
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr6_-_49078263 0.44 ENSDART00000032982
slc5a8l
solute carrier family 5 (iodide transporter), member 8-like
chr13_-_50309969 0.44 ENSDART00000191597
CU928131.1

chr7_-_52842007 0.44 ENSDART00000182710
map1aa
microtubule-associated protein 1Aa
chr8_-_12468744 0.44 ENSDART00000135019
FIBCD1 (1 of many)
si:dkeyp-51b7.3
chr24_-_22702017 0.44 ENSDART00000179403
ctnnd2a
catenin (cadherin-associated protein), delta 2a
chr11_-_43948885 0.43 ENSDART00000164522
CABZ01074203.1

chr4_+_70967639 0.43 ENSDART00000159230
si:dkeyp-80d11.12
si:dkeyp-80d11.12
chr9_+_4306122 0.43 ENSDART00000193722
ENSDART00000190521
kalrna
kalirin RhoGEF kinase a
chr17_-_39886628 0.43 ENSDART00000002217
zmp:0000000545
zmp:0000000545
chr25_-_12203952 0.43 ENSDART00000158204
ENSDART00000091727
ntrk3a
neurotrophic tyrosine kinase, receptor, type 3a
chr4_+_26628822 0.42 ENSDART00000191030
ENSDART00000186113
ENSDART00000186764
ENSDART00000165158
iqsec3a
IQ motif and Sec7 domain 3a
chr6_+_515181 0.42 ENSDART00000171374
CACNA1I (1 of many)
si:ch73-379f7.5
chr22_-_20575679 0.42 ENSDART00000089033
lingo3a
leucine rich repeat and Ig domain containing 3a
chr7_-_44672095 0.42 ENSDART00000073745
cmtm4
CKLF-like MARVEL transmembrane domain containing 4
chr7_-_74090168 0.42 ENSDART00000050528
tyrp1a
tyrosinase-related protein 1a
chr19_-_42651615 0.42 ENSDART00000123360
susd5
sushi domain containing 5
chr2_+_5300405 0.42 ENSDART00000019925
GNB4
G protein subunit beta 4
chr6_-_8489810 0.42 ENSDART00000124643
rasal3
RAS protein activator like 3
chr17_-_8169774 0.41 ENSDART00000091828
syne1b
spectrin repeat containing, nuclear envelope 1b
chr16_-_6821927 0.41 ENSDART00000149070
ENSDART00000149570
mbpb
myelin basic protein b
chr6_+_23887314 0.41 ENSDART00000163188
znf648
zinc finger protein 648
chr1_+_38858399 0.41 ENSDART00000165454
CU915762.1

chr18_+_27101096 0.40 ENSDART00000171128
ENSDART00000086094
plekha7a
pleckstrin homology domain containing, family A member 7a
chr7_+_33279108 0.39 ENSDART00000084530
coro2ba
coronin, actin binding protein, 2Ba
chr16_-_2414063 0.39 ENSDART00000073621
zgc:152945
zgc:152945

Network of associatons between targets according to the STRING database.

First level regulatory network of pgr

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.3 1.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3 1.0 GO:0006145 allantoin catabolic process(GO:0000256) purine nucleobase catabolic process(GO:0006145)
0.3 1.0 GO:0055091 phospholipid homeostasis(GO:0055091)
0.2 1.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 0.9 GO:0010039 response to iron ion(GO:0010039)
0.2 1.1 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 0.7 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.2 0.5 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.2 0.6 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.2 1.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.6 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.6 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 2.3 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 1.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.7 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 1.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 0.9 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 1.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.2 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.5 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.3 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 0.8 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.3 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 1.2 GO:0016203 muscle attachment(GO:0016203)
0.1 0.7 GO:0003315 heart rudiment formation(GO:0003315)
0.1 2.6 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 1.7 GO:0051180 vitamin transport(GO:0051180)
0.1 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 0.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:0016559 peroxisome fission(GO:0016559)
0.0 1.3 GO:0001757 somite specification(GO:0001757)
0.0 0.8 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.4 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.7 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 2.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 1.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.0 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.5 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 3.9 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 0.4 GO:0015816 glycine transport(GO:0015816)
0.0 0.3 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 1.7 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.5 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.2 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 1.3 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.0 0.3 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.7 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.4 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.7 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.8 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 5.5 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.1 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.4 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.4 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 3.1 GO:0007601 visual perception(GO:0007601)
0.0 0.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 3.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0070293 renal absorption(GO:0070293)
0.0 1.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.5 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 1.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.0 0.2 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.1 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.6 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.8 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.8 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 2.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.4 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.7 GO:0033270 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.6 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.0 1.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 4.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 2.9 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 1.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 4.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0005499 vitamin D binding(GO:0005499)
0.5 2.0 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.4 1.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 1.0 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.3 0.9 GO:0003994 aconitate hydratase activity(GO:0003994)
0.3 1.0 GO:0050897 cobalt ion binding(GO:0050897)
0.2 0.6 GO:0046978 TAP1 binding(GO:0046978)
0.2 2.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.7 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 1.8 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.4 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.9 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.4 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.8 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.2 GO:0008887 glycerate kinase activity(GO:0008887)
0.1 0.3 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.9 GO:0030552 cAMP binding(GO:0030552)
0.1 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 3.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 1.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.1 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 4.1 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.7 GO:0005244 voltage-gated ion channel activity(GO:0005244)
0.0 1.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR