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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pou1f1

Z-value: 0.34

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Transcription factors associated with pou1f1

Gene Symbol Gene ID Gene Info
pou1f1
ENSDARG00000058924 POU class 1 homeobox 1
pou1f1
ENSDARG00000110816 POU class 1 homeobox 1
pou1f1
ENSDARG00000115109 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou1f1dr11_v1_chr9_-_19161982_191619820.126.3e-01Click!

Activity profile of pou1f1 motif

Sorted Z-values of pou1f1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22099536 2.86 ENSDART00000101923
CR391987.1

chr12_-_17712393 2.01 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr9_-_22213297 1.67 ENSDART00000110656
ENSDART00000133149
crygm2d20
crystallin, gamma M2d20
chr14_+_46313396 1.05 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr21_-_20939488 1.03 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr25_+_31227747 0.86 ENSDART00000033872
tnni2a.1
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr5_-_44829719 0.81 ENSDART00000019104
fbp2
fructose-1,6-bisphosphatase 2
chr2_+_2223837 0.79 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr9_+_18716485 0.77 ENSDART00000135125
serp2
stress-associated endoplasmic reticulum protein family member 2
chr4_+_9669717 0.77 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr20_-_40755614 0.64 ENSDART00000061247
cx32.3
connexin 32.3
chr16_-_28856112 0.64 ENSDART00000078543
syt11b
synaptotagmin XIb
chr16_-_12173554 0.59 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr9_+_54290896 0.57 ENSDART00000149175
pou4f3
POU class 4 homeobox 3
chr23_+_31405497 0.55 ENSDART00000053546
sh3bgrl2
SH3 domain binding glutamate-rich protein like 2
chr4_-_5302866 0.52 ENSDART00000138590
SNAP91 (1 of many)
si:ch211-214j24.9
chr9_+_34641237 0.50 ENSDART00000133996
shox
short stature homeobox
chr20_-_5291012 0.50 ENSDART00000122892
cyp46a1.3
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr9_+_2574122 0.50 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr13_-_29420885 0.49 ENSDART00000024225
chata
choline O-acetyltransferase a
chr23_-_20051369 0.49 ENSDART00000049836
bgnb
biglycan b
chr5_-_41494831 0.49 ENSDART00000051081
eef2l2
eukaryotic translation elongation factor 2, like 2
chr7_+_24573721 0.47 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr6_+_39905021 0.47 ENSDART00000064904
endou
endonuclease, polyU-specific
chr5_-_71705191 0.47 ENSDART00000187767
ak1
adenylate kinase 1
chr16_+_46111849 0.47 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr19_+_10339538 0.47 ENSDART00000151808
ENSDART00000151235
rcvrn3
recoverin 3
chr8_-_33114202 0.44 ENSDART00000098840
ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr3_+_23092762 0.43 ENSDART00000142884
ENSDART00000024136
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr19_-_26869103 0.43 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr18_+_924949 0.43 ENSDART00000170888
ENSDART00000193163
pkma
pyruvate kinase M1/2a
chr7_-_66868543 0.43 ENSDART00000149680
ampd3a
adenosine monophosphate deaminase 3a
chr11_+_30663300 0.40 ENSDART00000161662
ttbk1a
tau tubulin kinase 1a
chr1_-_22757145 0.40 ENSDART00000134719
prom1b
prominin 1 b
chr15_-_46779934 0.40 ENSDART00000085136
clcn2c
chloride channel 2c
chr6_-_11768198 0.40 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr18_+_39487486 0.39 ENSDART00000126978
acadl
acyl-CoA dehydrogenase long chain
chr5_+_2815021 0.39 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr7_+_73397283 0.39 ENSDART00000174390
CABZ01081780.1

chr6_-_28980756 0.38 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr16_-_22781446 0.37 ENSDART00000144107
lenep
lens epithelial protein
chr3_-_48716422 0.36 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr21_-_22635245 0.36 ENSDART00000115224
ENSDART00000101782
nectin1a
nectin cell adhesion molecule 1a
chr13_+_24279021 0.36 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr16_-_28658341 0.35 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr17_-_12336987 0.34 ENSDART00000172001
snap25b
synaptosomal-associated protein, 25b
chr20_-_44557037 0.33 ENSDART00000140995
mfsd2b
major facilitator superfamily domain containing 2B
chr11_+_30057762 0.33 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr2_-_7666021 0.33 ENSDART00000180007
CABZ01021592.1

chr1_-_22512063 0.32 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr25_-_4146947 0.32 ENSDART00000129268
fads2
fatty acid desaturase 2
chr1_-_15797663 0.32 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr25_+_14087045 0.32 ENSDART00000155770
actc1c
actin, alpha, cardiac muscle 1c
chr22_-_13851297 0.31 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr20_-_34750363 0.31 ENSDART00000152845
znf395b
zinc finger protein 395b
chr11_-_29737088 0.30 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr8_+_7359294 0.30 ENSDART00000121708
pcsk1nl
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr16_+_9540033 0.30 ENSDART00000149574
ca14
carbonic anhydrase XIV
chr4_+_22480169 0.30 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr19_+_43297546 0.30 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr16_-_38118003 0.29 ENSDART00000058667
si:dkey-23o4.6
si:dkey-23o4.6
chr9_-_42418470 0.29 ENSDART00000144353
calcrla
calcitonin receptor-like a
chr16_+_36671064 0.29 ENSDART00000109703
col6a4a
collagen, type VI, alpha 4a
chr5_-_30382925 0.28 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr3_-_20040636 0.28 ENSDART00000104118
atxn7l3
ataxin 7-like 3
chr5_+_69747417 0.27 ENSDART00000153717
si:ch211-275j6.5
si:ch211-275j6.5
chr1_+_44127292 0.27 ENSDART00000160542
cabp2a
calcium binding protein 2a
chr6_+_52350443 0.27 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr10_+_26747755 0.27 ENSDART00000100329
f9b
coagulation factor IXb
chr16_-_12173399 0.27 ENSDART00000142574
clstn3
calsyntenin 3
chr2_-_9059955 0.26 ENSDART00000022768
ak5
adenylate kinase 5
chr7_+_23515966 0.26 ENSDART00000186893
ENSDART00000186189
zgc:109889
zgc:109889
chr3_+_23029934 0.26 ENSDART00000110343
nags
N-acetylglutamate synthase
chr9_-_43538328 0.26 ENSDART00000140526
znf385b
zinc finger protein 385B
chr1_-_23040358 0.25 ENSDART00000146871
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr12_-_558201 0.25 ENSDART00000168586
ENSDART00000158355
bsk146
brain specific kinase 146
chr17_+_16564921 0.25 ENSDART00000151904
foxn3
forkhead box N3
chr21_-_43015383 0.25 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr13_+_9432501 0.25 ENSDART00000058064
zgc:123321
zgc:123321
chr20_-_34750045 0.25 ENSDART00000186130
znf395b
zinc finger protein 395b
chr20_+_4060839 0.25 ENSDART00000178565
TRIM67
tripartite motif containing 67
chr12_+_3022882 0.24 ENSDART00000122905
rac3b
Rac family small GTPase 3b
chr2_+_20430366 0.24 ENSDART00000155108
si:ch211-153l6.6
si:ch211-153l6.6
chr10_-_36927594 0.24 ENSDART00000162046
sez6a
seizure related 6 homolog a
chr15_+_25438714 0.24 ENSDART00000154164
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr21_-_14811058 0.23 ENSDART00000143100
phpt1
phosphohistidine phosphatase 1
chr20_+_19512727 0.23 ENSDART00000063696
atraid
all-trans retinoic acid-induced differentiation factor
chr6_+_40714811 0.23 ENSDART00000153868
ccdc36
coiled-coil domain containing 36
chr6_-_35779348 0.23 ENSDART00000191159
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr1_+_25801648 0.23 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr12_-_41684729 0.23 ENSDART00000184461
jakmip3
Janus kinase and microtubule interacting protein 3
chr1_+_39482588 0.23 ENSDART00000181790
tenm3
teneurin transmembrane protein 3
chr1_+_51721851 0.23 ENSDART00000040397
prdx2
peroxiredoxin 2
chr5_-_6377865 0.23 ENSDART00000031775
zgc:73226
zgc:73226
chr2_+_44571200 0.23 ENSDART00000098132
klhl24a
kelch-like family member 24a
chr20_+_32552912 0.22 ENSDART00000009691
scml4
Scm polycomb group protein like 4
chr10_-_33621739 0.21 ENSDART00000142655
ENSDART00000128049
hunk
hormonally up-regulated Neu-associated kinase
chr24_+_40529346 0.21 ENSDART00000168548
CU929259.1

chr5_-_55933420 0.21 ENSDART00000050966
slc25a46
solute carrier family 25, member 46
chr12_+_1139690 0.21 ENSDART00000160442
CABZ01072885.1

chr7_-_11596450 0.21 ENSDART00000173863
stard5
StAR-related lipid transfer (START) domain containing 5
chr13_-_2010191 0.21 ENSDART00000161021
ENSDART00000124134
gfral
GDNF family receptor alpha like
chr3_+_26145013 0.21 ENSDART00000162546
ENSDART00000129561
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr9_+_54039006 0.21 ENSDART00000112441
tlr7
toll-like receptor 7
chr24_-_26328721 0.20 ENSDART00000125468
apodb
apolipoprotein Db
chr13_-_29421331 0.20 ENSDART00000150228
chata
choline O-acetyltransferase a
chr16_-_31622777 0.20 ENSDART00000137311
ENSDART00000002930
phf20l1
PHD finger protein 20 like 1
chr11_-_1935883 0.20 ENSDART00000172885
faim2b
Fas apoptotic inhibitory molecule 2b
chr21_+_22840246 0.20 ENSDART00000151621
birc2
baculoviral IAP repeat containing 2
chr16_+_51326237 0.20 ENSDART00000168525
CU469384.1

chr11_-_2838699 0.20 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr8_-_2434282 0.20 ENSDART00000137262
ENSDART00000134044
vdac3
voltage-dependent anion channel 3
chr5_-_2282256 0.19 ENSDART00000064012
ca4a
carbonic anhydrase IV a
chr5_-_42904329 0.19 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr22_+_1556948 0.19 ENSDART00000159050
si:ch211-255f4.8
si:ch211-255f4.8
chr8_-_39952727 0.19 ENSDART00000181310
cabp1a
calcium binding protein 1a
chr8_-_25422186 0.18 ENSDART00000113492
ENSDART00000131736
kcnq2a
potassium voltage-gated channel, KQT-like subfamily, member 2a
chr17_+_45602640 0.18 ENSDART00000153822
si:ch211-202f3.4
si:ch211-202f3.4
chr9_+_21826724 0.18 ENSDART00000101985
zgc:162944
zgc:162944
chr6_+_612594 0.18 ENSDART00000150903
kynu
kynureninase
chr6_-_24053404 0.18 ENSDART00000168511
si:dkey-44g17.6
si:dkey-44g17.6
chr8_+_8845932 0.18 ENSDART00000112028
si:ch211-180f4.1
si:ch211-180f4.1
chr1_-_55118745 0.17 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr22_+_18469004 0.17 ENSDART00000061430
cilp2
cartilage intermediate layer protein 2
chr15_+_9327252 0.17 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr22_-_26865181 0.17 ENSDART00000138311
hmox2a
heme oxygenase 2a
chr14_-_413273 0.17 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr4_+_5255041 0.17 ENSDART00000137966
ccdc167
coiled-coil domain containing 167
chr14_-_7207961 0.17 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr3_+_36424055 0.17 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr10_-_26766780 0.17 ENSDART00000146666
mcf2b
MCF.2 cell line derived transforming sequence b
chr2_+_16160906 0.17 ENSDART00000135783
selenoj
selenoprotein J
chr1_-_54063520 0.17 ENSDART00000171722
smdt1b
single-pass membrane protein with aspartate-rich tail 1b
chr11_+_40812590 0.16 ENSDART00000186690
errfi1a
ERBB receptor feedback inhibitor 1a
chr10_-_35236949 0.16 ENSDART00000145804
ypel2a
yippee-like 2a
chr2_-_1548330 0.16 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr20_+_41756996 0.16 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr4_+_19700308 0.16 ENSDART00000027919
pax4
paired box 4
chr9_+_34127005 0.16 ENSDART00000167384
ENSDART00000078065
f5
coagulation factor V
chr20_+_41664350 0.15 ENSDART00000186247
fam184a
family with sequence similarity 184, member A
chr18_+_35128685 0.15 ENSDART00000151579
si:ch211-195m9.3
si:ch211-195m9.3
chr17_-_30702411 0.15 ENSDART00000114358
zgc:194392
zgc:194392
chr22_-_31060579 0.15 ENSDART00000182376
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr8_+_26141680 0.15 ENSDART00000078334
celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr20_+_66857 0.15 ENSDART00000114999
lrfn2b
leucine rich repeat and fibronectin type III domain containing 2b
chr8_-_17987547 0.15 ENSDART00000112699
ENSDART00000061747
fpgt
fucose-1-phosphate guanylyltransferase
chr14_-_2209742 0.15 ENSDART00000054889
pcdh2ab5
protocadherin 2 alpha b 5
chr21_+_21195487 0.14 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr11_-_26832685 0.14 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr16_+_12836143 0.14 ENSDART00000067741
cacng6b
calcium channel, voltage-dependent, gamma subunit 6b
chr15_+_34592215 0.14 ENSDART00000099776
tspan13a
tetraspanin 13a
chr1_-_58975098 0.14 ENSDART00000189899
CABZ01114581.1

chr10_+_17776981 0.14 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr23_-_3511630 0.14 ENSDART00000019667
rnf114
ring finger protein 114
chr18_-_47662696 0.14 ENSDART00000184260
CABZ01073963.1

chr8_+_52637507 0.14 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr13_+_7292061 0.13 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr21_+_45841731 0.13 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr2_+_36007449 0.13 ENSDART00000161837
lamc2
laminin, gamma 2
chr14_-_4145594 0.13 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr16_+_3068080 0.13 ENSDART00000160092
cyb5r4
cytochrome b5 reductase 4
chr14_-_30141162 0.13 ENSDART00000053916
mtnr1ab
melatonin receptor 1A b
chr12_-_9132682 0.13 ENSDART00000066471
adam8b
ADAM metallopeptidase domain 8b
chr23_+_7710447 0.13 ENSDART00000168199
kif3b
kinesin family member 3B
chr4_-_2219705 0.13 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr13_+_15656042 0.13 ENSDART00000134240
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr22_+_23359369 0.13 ENSDART00000170886
dennd1b
DENN/MADD domain containing 1B
chr15_-_38154616 0.13 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr12_+_4222854 0.13 ENSDART00000144881
mapk7
mitogen-activated protein kinase 7
chr21_-_32060993 0.12 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr18_+_15616167 0.12 ENSDART00000080454
slc17a8
solute carrier family 17 (vesicular glutamate transporter), member 8
chr25_-_19420949 0.12 ENSDART00000181338
map1ab
microtubule-associated protein 1Ab
chr2_-_7843451 0.12 ENSDART00000163265
si:ch211-38m6.7
si:ch211-38m6.7
chr9_+_7724152 0.12 ENSDART00000061716
mnx2a
motor neuron and pancreas homeobox 2a
chr21_-_38853737 0.12 ENSDART00000184100
tlr22
toll-like receptor 22
chr10_-_34916208 0.12 ENSDART00000187371
ccna1
cyclin A1
chr1_+_6862917 0.12 ENSDART00000182953
erbb4a
erb-b2 receptor tyrosine kinase 4a
chr10_-_14556978 0.12 ENSDART00000126643
zgc:153395
zgc:153395
chr9_-_40765868 0.12 ENSDART00000138634
abca12
ATP-binding cassette, sub-family A (ABC1), member 12
chr7_-_22632690 0.12 ENSDART00000165245
si:dkey-112a7.4
si:dkey-112a7.4
chr2_+_29491314 0.12 ENSDART00000181774
dlgap1a
discs, large (Drosophila) homolog-associated protein 1a
chr4_+_20051478 0.12 ENSDART00000143642
lamtor4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr7_+_49800849 0.11 ENSDART00000164838
ENSDART00000187888
PAMR1 (1 of many)
si:ch211-102l7.3
chr23_-_41965557 0.11 ENSDART00000144183
slc1a7b
solute carrier family 1 (glutamate transporter), member 7b
chr22_+_1586060 0.11 ENSDART00000160793
si:ch211-255f4.11
si:ch211-255f4.11
chr3_+_7808459 0.11 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr4_-_27897160 0.11 ENSDART00000066924
ENSDART00000066925
ENSDART00000193020
tbc1d22a
TBC1 domain family, member 22a
chr4_-_73136420 0.11 ENSDART00000160907
si:ch73-170d6.3
si:ch73-170d6.3
chr7_-_71829649 0.11 ENSDART00000160449
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr22_-_10121880 0.11 ENSDART00000002348
rdh5
retinol dehydrogenase 5 (11-cis/9-cis)
chr8_+_17987778 0.11 ENSDART00000133429
lrriq3
leucine-rich repeats and IQ motif containing 3
chr19_+_12915498 0.11 ENSDART00000132892
cthrc1a
collagen triple helix repeat containing 1a
chr20_-_29864390 0.11 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr2_-_16216568 0.11 ENSDART00000173758
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr9_+_45227028 0.11 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr9_-_25989989 0.11 ENSDART00000090052
arhgap15
Rho GTPase activating protein 15
chr14_+_36521005 0.11 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr8_+_17987215 0.11 ENSDART00000113605
lrriq3
leucine-rich repeats and IQ motif containing 3
chr2_+_20605925 0.11 ENSDART00000191510
olfml2bb
olfactomedin-like 2Bb
chr14_-_28534563 0.11 ENSDART00000054088
zgc:113364
zgc:113364

Network of associatons between targets according to the STRING database.

First level regulatory network of pou1f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.2 0.7 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.1 0.4 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.4 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.2 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.2 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 0.2 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.2 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.2 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 0.2 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.2 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.8 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0019430 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 3.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0043584 nose development(GO:0043584)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.2 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.5 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.1 GO:0070285 pigment cell development(GO:0070285)
0.0 0.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0021654 rhombomere boundary formation(GO:0021654)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.1 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.0 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.0 0.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0030282 bone mineralization(GO:0030282)
0.0 0.1 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0071914 prominosome(GO:0071914)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.4 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 0.3 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.5 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 2.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.1 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.4 GO:0008308 voltage-gated chloride channel activity(GO:0005247) voltage-gated anion channel activity(GO:0008308)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis