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PRJEB1986: zebrafish developmental stages transcriptome

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Results for pou2f3

Z-value: 0.97

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Transcription factors associated with pou2f3

Gene Symbol Gene ID Gene Info
pou2f3
ENSDARG00000052387 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f3dr11_v1_chr5_+_58550795_585507950.446.0e-02Click!

Activity profile of pou2f3 motif

Sorted Z-values of pou2f3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_14052349 3.99 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr17_-_37395460 3.10 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr16_+_26012569 3.05 ENSDART00000148846
prss59.1
protease, serine, 59, tandem duplicate 1
chr25_+_35189555 3.03 ENSDART00000044453
ano5a
anoctamin 5a
chr25_+_31277415 2.94 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr9_+_49659114 2.90 ENSDART00000189643
CSRNP3
cysteine and serine rich nuclear protein 3
chr14_+_15155684 2.88 ENSDART00000167966
zgc:158852
zgc:158852
chr5_-_6567464 2.82 ENSDART00000184985
tnks1bp1
tankyrase 1 binding protein 1
chr14_-_46238186 2.80 ENSDART00000173245
si:ch211-113d11.6
si:ch211-113d11.6
chr16_+_2820340 2.71 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr18_-_20869175 2.66 ENSDART00000090079
synm
synemin, intermediate filament protein
chr9_-_22158325 2.48 ENSDART00000114568
crygm2d16
crystallin, gamma M2d16
chr9_-_22129788 2.46 ENSDART00000124272
ENSDART00000175417
crygm2d8
crystallin, gamma M2d8
chr8_+_22931427 2.43 ENSDART00000063096
sypa
synaptophysin a
chr24_+_402493 2.32 ENSDART00000036472
VSTM2A
zgc:110852
chr6_+_6924637 2.29 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr25_+_31227747 2.24 ENSDART00000033872
tnni2a.1
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr4_-_8903240 2.23 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr16_-_52540056 2.15 ENSDART00000188304
CR293507.1

chr21_-_37733571 2.15 ENSDART00000176214
mpp1
membrane protein, palmitoylated 1
chr11_-_762721 2.03 ENSDART00000166465
syn2b
synapsin IIb
chr19_-_205104 2.03 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr12_-_21834611 2.00 ENSDART00000179553
thrab
thyroid hormone receptor alpha b
chr16_+_46111849 1.98 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr11_+_37275448 1.95 ENSDART00000161423
creld1a
cysteine-rich with EGF-like domains 1a
chr13_+_24022963 1.88 ENSDART00000028285
pgbd5
piggyBac transposable element derived 5
chr13_-_2189761 1.88 ENSDART00000166255
mlip
muscular LMNA-interacting protein
chr3_+_45687266 1.83 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr9_-_9982696 1.80 ENSDART00000192548
ENSDART00000125852
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr24_-_7321928 1.80 ENSDART00000167570
ENSDART00000045150
actr3b
ARP3 actin related protein 3 homolog B
chr18_+_3579829 1.80 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr22_+_18389271 1.75 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr1_+_25801648 1.71 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr6_-_54796072 1.69 ENSDART00000164445
tnnt2b
troponin T type 2b (cardiac)
chr25_+_24291156 1.67 ENSDART00000083407
b4galnt4a
beta-1,4-N-acetyl-galactosaminyl transferase 4a
chr5_+_4332220 1.67 ENSDART00000051699
sat1a.1
spermidine/spermine N1-acetyltransferase 1a, duplicate 1
chr13_+_2442841 1.66 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
arfgef3
ARFGEF family member 3
chr25_+_37285737 1.64 ENSDART00000126879
tmed6
transmembrane p24 trafficking protein 6
chr19_-_5345930 1.62 ENSDART00000066620
ENSDART00000151398
krtt1c19e
keratin type 1 c19e
chr3_-_46410387 1.57 ENSDART00000156822
cdip1
cell death-inducing p53 target 1
chr19_+_1510971 1.56 ENSDART00000157721
SLC45A4 (1 of many)
solute carrier family 45 member 4
chr23_-_35066816 1.55 ENSDART00000168731
ENSDART00000163731
BX294434.1

chr16_-_12173554 1.54 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr19_+_5076617 1.49 ENSDART00000189990
eno2
enolase 2
chr20_-_4031475 1.47 ENSDART00000112053
fam89a
family with sequence similarity 89, member A
chr22_+_14051894 1.41 ENSDART00000142548
aox6
aldehyde oxidase 6
chr20_-_46817223 1.40 ENSDART00000100336
esrrgb
estrogen-related receptor gamma b
chr2_-_52455525 1.40 ENSDART00000160768
ENSDART00000002241
chico
chico
chr2_-_1443692 1.38 ENSDART00000004533
rpe65a
retinal pigment epithelium-specific protein 65a
chr19_-_5103313 1.38 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr14_+_32839535 1.37 ENSDART00000168975
arr3b
arrestin 3b, retinal (X-arrestin)
chr3_+_22327738 1.36 ENSDART00000055675
gh1
growth hormone 1
chr11_+_30817943 1.36 ENSDART00000150130
ENSDART00000159997
cacna1ab
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b
chr1_-_21901589 1.34 ENSDART00000140553
frmpd1a
FERM and PDZ domain containing 1a
chr12_+_48480632 1.33 ENSDART00000158157
arhgap44
Rho GTPase activating protein 44
chr16_-_12173399 1.31 ENSDART00000142574
clstn3
calsyntenin 3
chr6_+_49722970 1.30 ENSDART00000155934
ENSDART00000154738
stx16
syntaxin 16
chr9_-_30165621 1.29 ENSDART00000089543
abi3bpa
ABI family, member 3 (NESH) binding protein a
chr25_-_3503458 1.27 ENSDART00000173269
PRKAR2B
si:ch211-272n13.7
chr25_-_25058508 1.26 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr20_+_9128829 1.24 ENSDART00000064144
ENSDART00000137450
bpnt1
bisphosphate nucleotidase 1
chr11_+_30000814 1.24 ENSDART00000191011
ENSDART00000189770
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr20_-_39789036 1.24 ENSDART00000086405
ENSDART00000098253
rnf217
ring finger protein 217
chr18_+_7283283 1.24 ENSDART00000141493
ANO2 (1 of many)
si:ch73-86n2.1
chr4_+_25950372 1.24 ENSDART00000125767
metap2a
methionyl aminopeptidase 2a
chr20_-_14206698 1.23 ENSDART00000082441
dlgap2b
discs, large (Drosophila) homolog-associated protein 2b
chr16_+_14029283 1.22 ENSDART00000146165
ENSDART00000132075
rusc1
RUN and SH3 domain containing 1
chr3_-_5067585 1.21 ENSDART00000169609
tefb
thyrotrophic embryonic factor b
chr5_-_64883082 1.20 ENSDART00000064983
ENSDART00000139066
krt1-c5
keratin, type 1, gene c5
chr16_+_50089417 1.19 ENSDART00000153675
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr11_-_37880492 1.19 ENSDART00000102868
etnk2
ethanolamine kinase 2
chr19_-_8096984 1.18 ENSDART00000146987
si:dkey-266f7.9
si:dkey-266f7.9
chr3_+_59851537 1.17 ENSDART00000180997
CU693479.1

chr5_-_13206878 1.16 ENSDART00000051666
ppm1f
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr6_+_49723289 1.16 ENSDART00000190452
stx16
syntaxin 16
chr6_+_55174744 1.16 ENSDART00000023562
SYT2
synaptotagmin 2
chr20_+_41664350 1.15 ENSDART00000186247
fam184a
family with sequence similarity 184, member A
chr8_-_7444390 1.14 ENSDART00000149671
hdac6
histone deacetylase 6
chr13_-_2215213 1.13 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr24_-_24849091 1.13 ENSDART00000133649
ENSDART00000038290
crhb
corticotropin releasing hormone b
chr14_+_597532 1.13 ENSDART00000159805
LO018568.2

chr24_-_41220538 1.11 ENSDART00000150207
acvr2ba
activin A receptor type 2Ba
chr6_+_51773873 1.09 ENSDART00000156516
tmem74b
transmembrane protein 74B
chr14_-_9713549 1.07 ENSDART00000193356
ENSDART00000166739
si:zfos-2326c3.2
si:zfos-2326c3.2
chr23_-_27345425 1.07 ENSDART00000022042
ENSDART00000191870
scn8aa
sodium channel, voltage gated, type VIII, alpha subunit a
chr24_+_792429 1.06 ENSDART00000082523
impa2
inositol(myo)-1(or 4)-monophosphatase 2
chr7_-_18168493 1.06 ENSDART00000127428
peli3
pellino E3 ubiquitin protein ligase family member 3
chr14_-_2213660 1.05 ENSDART00000162537
pcdh2ab3
protocadherin 2 alpha b 3
chr5_-_16983336 1.05 ENSDART00000038740
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr4_-_390431 1.04 ENSDART00000067482
ENSDART00000138500
dynlt1
dynein, light chain, Tctex-type 1
chr1_+_53954230 1.04 ENSDART00000037729
ENSDART00000159900
ccsapa
centriole, cilia and spindle-associated protein a
chr3_-_41791178 1.04 ENSDART00000049687
grifin
galectin-related inter-fiber protein
chr10_-_14929392 1.03 ENSDART00000137430
smad2
SMAD family member 2
chr1_-_30510839 1.03 ENSDART00000168189
ENSDART00000174868
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr24_-_39772045 1.01 ENSDART00000087441
GFOD1
si:ch211-276f18.2
chr2_-_48171112 1.00 ENSDART00000156258
pfkpb
phosphofructokinase, platelet b
chr17_-_30975707 0.99 ENSDART00000138346
evla
Enah/Vasp-like a
chr6_+_36381709 0.99 ENSDART00000004727
rhcgl1
Rh family, C glycoprotein, like 1
chr17_+_3993772 0.99 ENSDART00000170822
ENSDART00000168613
ENSDART00000186174
tmx4
thioredoxin-related transmembrane protein 4
chr24_-_1985007 0.99 ENSDART00000189870
PARD3 (1 of many)
par-3 family cell polarity regulator
chr4_-_27398385 0.98 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr19_+_935565 0.97 ENSDART00000113368
RNF5
ring finger protein 5
chr8_+_52637507 0.96 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr6_-_37469775 0.96 ENSDART00000156546
plcxd1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr9_-_7212973 0.95 ENSDART00000133638
mgat4a
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr9_-_6380653 0.95 ENSDART00000078523
ecrg4a
esophageal cancer related gene 4a
chr21_-_37733287 0.94 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr9_+_38481780 0.94 ENSDART00000087241
lss
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr7_-_58098814 0.93 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr17_+_12075805 0.93 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr25_-_4146947 0.93 ENSDART00000129268
fads2
fatty acid desaturase 2
chr14_-_4121052 0.92 ENSDART00000167074
irf2
interferon regulatory factor 2
chr6_-_6346557 0.92 ENSDART00000115018
ccdc88aa
coiled-coil domain containing 88Aa
chr17_+_3128273 0.92 ENSDART00000122453
zgc:136872
zgc:136872
chr14_+_3495542 0.91 ENSDART00000168934
gstp2
glutathione S-transferase pi 2
chr13_-_34683370 0.91 ENSDART00000113661
kif16bb
kinesin family member 16Bb
chr24_-_17892325 0.91 ENSDART00000154039
ENSDART00000185619
ENSDART00000178326
cntnap2a
contactin associated protein like 2a
chr17_+_42842632 0.90 ENSDART00000155547
ENSDART00000126087
qpct
glutaminyl-peptide cyclotransferase
chr14_-_33613794 0.89 ENSDART00000010022
xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr10_-_42685512 0.88 ENSDART00000081347
stc1l
stanniocalcin 1, like
chr11_+_36409457 0.87 ENSDART00000077641
cyb561d1
cytochrome b561 family, member D1
chr17_-_6076084 0.87 ENSDART00000058890
ephx2
epoxide hydrolase 2, cytoplasmic
chr8_+_28900689 0.87 ENSDART00000141634
grid2
glutamate receptor, ionotropic, delta 2
chr24_+_5208171 0.87 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
si:ch73-206p6.1
chr24_-_39771667 0.84 ENSDART00000181867
GFOD1
si:ch211-276f18.2
chr1_-_44413629 0.84 ENSDART00000192747
CT583626.1

chr5_-_18897482 0.83 ENSDART00000010101
ENSDART00000099434
aacs
acetoacetyl-CoA synthetase
chr13_+_19884631 0.83 ENSDART00000089533
atrnl1a
attractin-like 1a
chr18_+_16125852 0.83 ENSDART00000061106
bhlhe41
basic helix-loop-helix family, member e41
chr6_-_24053404 0.82 ENSDART00000168511
si:dkey-44g17.6
si:dkey-44g17.6
chr9_+_48943471 0.81 ENSDART00000125090
stk39
serine threonine kinase 39
chr12_-_33706726 0.80 ENSDART00000153135
myo15b
myosin XVB
chr15_+_46356879 0.80 ENSDART00000154388
wu:fb18f06
wu:fb18f06
chr22_+_38301365 0.79 ENSDART00000137339
traf5
Tnf receptor-associated factor 5
chr8_-_49399470 0.79 ENSDART00000136395
si:ch211-194e1.7
si:ch211-194e1.7
chr10_-_35103208 0.77 ENSDART00000192734
zgc:110006
zgc:110006
chr3_-_23407720 0.77 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr11_+_30162407 0.77 ENSDART00000190333
ENSDART00000127502
cdkl5
cyclin-dependent kinase-like 5
chr11_-_42918971 0.76 ENSDART00000052912
pcdh20
protocadherin 20
chr5_-_16425781 0.76 ENSDART00000185624
ENSDART00000180617
slc39a14
solute carrier family 39 (zinc transporter), member 14
chr11_+_23760470 0.76 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
nfasca
neurofascin homolog (chicken) a
chr14_-_4044545 0.76 ENSDART00000169527
snx25
sorting nexin 25
chr25_+_4787431 0.76 ENSDART00000170640
myo5c
myosin VC
chr19_-_5805923 0.75 ENSDART00000134340
si:ch211-264f5.8
si:ch211-264f5.8
chr11_+_30161699 0.75 ENSDART00000190504
cdkl5
cyclin-dependent kinase-like 5
chr12_+_17504559 0.74 ENSDART00000020628
cyth3a
cytohesin 3a
chr13_-_9895564 0.74 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
si:ch211-117n7.6
chr20_+_22045089 0.74 ENSDART00000063564
ENSDART00000187013
ENSDART00000161552
ENSDART00000174478
ENSDART00000063568
ENSDART00000152247
nmu
neuromedin U
chr21_+_26071874 0.74 ENSDART00000003001
ENSDART00000146573
rpl23a
ribosomal protein L23a
chr10_+_2582254 0.74 ENSDART00000016103
nxnl2
nucleoredoxin like 2
chr17_-_6076266 0.74 ENSDART00000171084
ephx2
epoxide hydrolase 2, cytoplasmic
chr20_-_3087162 0.73 ENSDART00000152495
map3k5
mitogen-activated protein kinase kinase kinase 5
chr2_+_927204 0.73 ENSDART00000165477
AL935300.3

chr5_+_45138934 0.73 ENSDART00000041412
ENSDART00000136002
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_21931124 0.73 ENSDART00000137627
si:ch73-92i20.1
si:ch73-92i20.1
chr20_-_1268863 0.72 ENSDART00000109321
ENSDART00000027119
lats1
large tumor suppressor kinase 1
chr14_-_45967981 0.72 ENSDART00000188062
macrod1
MACRO domain containing 1
chr6_+_27275716 0.71 ENSDART00000156434
ENSDART00000114347
scly
selenocysteine lyase
chr8_-_65189 0.71 ENSDART00000168412
hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
chr13_+_47821524 0.71 ENSDART00000109978
zc3h6
zinc finger CCCH-type containing 6
chr15_-_30815826 0.71 ENSDART00000156160
ENSDART00000145918
msi2b
musashi RNA-binding protein 2b
chr5_-_64355227 0.70 ENSDART00000170787
fam78aa
family with sequence similarity 78, member Aa
chr16_-_383664 0.69 ENSDART00000051693
irx4a
iroquois homeobox 4a
chr3_-_45848257 0.69 ENSDART00000147198
igfals
insulin-like growth factor binding protein, acid labile subunit
chr16_+_36650984 0.69 ENSDART00000156780
col6a4a
collagen, type VI, alpha 4a
chr18_-_35390735 0.68 ENSDART00000098297
CABZ01040999.1

chr1_-_36152131 0.68 ENSDART00000182113
ENSDART00000182904
znf827
zinc finger protein 827
chr9_+_747612 0.67 ENSDART00000181004
insig2
insulin induced gene 2
chr11_+_25583950 0.67 ENSDART00000111961
ccdc120
coiled-coil domain containing 120
chr21_-_3826706 0.67 ENSDART00000053607
st6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_56080112 0.66 ENSDART00000075469
ENSDART00000161473
c3a.6
complement component c3a, duplicate 6
chr2_+_6926100 0.66 ENSDART00000153289
nos1apb
nitric oxide synthase 1 (neuronal) adaptor protein b
chr19_-_7450796 0.66 ENSDART00000104750
mllt11
MLLT11, transcription factor 7 cofactor
chr18_-_19405616 0.65 ENSDART00000191290
ENSDART00000090855
megf11
multiple EGF-like-domains 11
chr3_+_49021079 0.64 ENSDART00000162012
zgc:163083
zgc:163083
chr17_+_38476300 0.63 ENSDART00000123298
stard9
StAR-related lipid transfer (START) domain containing 9
chr10_+_2669405 0.63 ENSDART00000110202
ccl27b
chemokine (C-C motif) ligand 27b
chr9_-_1702648 0.63 ENSDART00000102934
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr11_-_37997419 0.63 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr17_-_3190070 0.63 ENSDART00000115027
tmem151bb
transmembrane protein 151Bb
chr5_+_22177033 0.62 ENSDART00000131223
fdx1b
ferredoxin 1b
chr17_+_43623598 0.62 ENSDART00000154138
znf365
zinc finger protein 365
chr5_+_64732036 0.62 ENSDART00000073950
olfm1a
olfactomedin 1a
chr6_-_30932078 0.62 ENSDART00000028612
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr17_-_8570257 0.62 ENSDART00000154713
ENSDART00000121488
fzd3b
frizzled class receptor 3b
chr5_+_44228526 0.62 ENSDART00000143789
TMEM8B
si:dkey-84j12.1
chr7_-_72427616 0.61 ENSDART00000181878
rph3ab
rabphilin 3A homolog (mouse), b
chr22_+_35275468 0.61 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr24_-_6898302 0.61 ENSDART00000158646
dpp6a
dipeptidyl-peptidase 6a
chr1_-_53756851 0.61 ENSDART00000122445
akt3b
v-akt murine thymoma viral oncogene homolog 3b
chr5_+_39504136 0.61 ENSDART00000121460
prdm8b
PR domain containing 8b
chr11_-_2478374 0.60 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr2_-_23778180 0.60 ENSDART00000136782
si:dkey-24c2.7
si:dkey-24c2.7
chr4_+_12292274 0.60 ENSDART00000061070
ENSDART00000150786
mkrn1
makorin, ring finger protein, 1
chr14_+_15231097 0.60 ENSDART00000172430
si:dkey-203a12.3
si:dkey-203a12.3
chr5_-_32274383 0.60 ENSDART00000122889
myhz1.3
myosin, heavy polypeptide 1.3, skeletal muscle
chr14_-_49133426 0.59 ENSDART00000042421
ppp2ca
protein phosphatase 2, catalytic subunit, alpha isozyme
chr7_-_69521481 0.59 ENSDART00000148465
slc1a1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr4_+_76426308 0.58 ENSDART00000180424
ENSDART00000159789
FP074874.1
zgc:172128

zgc:172128
chr5_+_51848756 0.58 ENSDART00000087467
ENSDART00000184466
cmya5
cardiomyopathy associated 5

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.5 2.0 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 1.7 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.4 1.7 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 1.7 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.4 1.1 GO:0035902 response to immobilization stress(GO:0035902)
0.3 1.4 GO:0016108 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.3 2.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 0.9 GO:0070314 G1 to G0 transition(GO:0070314)
0.3 0.9 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 1.2 GO:0070084 protein initiator methionine removal(GO:0070084)
0.3 1.4 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.3 1.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.3 0.8 GO:0033212 iron assimilation(GO:0033212)
0.2 0.5 GO:0019563 glycerol catabolic process(GO:0019563)
0.2 0.9 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.2 0.7 GO:2000639 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 2.5 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.2 1.1 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 0.6 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.2 2.0 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.2 1.4 GO:0032475 otolith formation(GO:0032475)
0.2 0.9 GO:0010447 response to acidic pH(GO:0010447) negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2 1.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 1.5 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 0.9 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 0.5 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.2 1.9 GO:0032196 transposition(GO:0032196)
0.2 0.5 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 0.5 GO:0035046 pronuclear migration(GO:0035046)
0.1 0.7 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 1.0 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 1.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.7 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 7.4 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 0.6 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 1.4 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.9 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.8 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 1.0 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.5 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.3 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.2 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.7 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.1 1.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.4 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 0.8 GO:0030431 sleep(GO:0030431)
0.1 0.2 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 1.2 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 1.6 GO:0060841 venous blood vessel development(GO:0060841)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.7 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 0.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.5 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.4 GO:0006953 acute-phase response(GO:0006953)
0.1 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.3 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.1 2.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0 0.5 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.9 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.7 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 1.2 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.4 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.7 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.0 5.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.8 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.3 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 3.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0070206 protein trimerization(GO:0070206) protein homotrimerization(GO:0070207)
0.0 1.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228) synaptic transmission, GABAergic(GO:0051932)
0.0 5.0 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.1 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.0 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.8 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.2 GO:0046620 regulation of organ growth(GO:0046620)
0.0 0.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.6 GO:0042181 ketone biosynthetic process(GO:0042181)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.6 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 1.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 4.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.2 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 1.2 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.3 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.8 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.9 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.9 GO:0051592 response to calcium ion(GO:0051592)
0.0 1.2 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.5 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.4 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.7 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.0 0.1 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.6 GO:0051693 actin filament capping(GO:0051693)
0.0 0.7 GO:0006956 complement activation(GO:0006956)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 1.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 7.4 GO:0005861 troponin complex(GO:0005861)
0.1 0.7 GO:0008091 spectrin(GO:0008091)
0.1 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.9 GO:0033010 paranodal junction(GO:0033010)
0.1 1.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 7.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.1 GO:0048179 activin receptor complex(GO:0048179)
0.1 3.0 GO:0016605 PML body(GO:0016605)
0.1 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.9 GO:0030315 T-tubule(GO:0030315)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 6.0 GO:0005882 intermediate filament(GO:0005882)
0.1 1.7 GO:0005844 polysome(GO:0005844)
0.0 1.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.5 GO:0031201 SNARE complex(GO:0031201)
0.0 1.2 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.0 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 5.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 2.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 3.2 GO:0030424 axon(GO:0030424)
0.0 2.1 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0005521 lamin binding(GO:0005521)
0.5 1.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.5 2.0 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.5 1.4 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.5 1.4 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.4 1.1 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.3 1.0 GO:0048030 disaccharide binding(GO:0048030)
0.3 1.4 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.3 1.7 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.3 0.8 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.2 1.7 GO:0019809 spermidine binding(GO:0019809)
0.2 0.9 GO:0071253 connexin binding(GO:0071253)
0.2 0.9 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 0.6 GO:0030882 lipid antigen binding(GO:0030882)
0.2 1.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 0.5 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.2 1.7 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 4.5 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.5 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.2 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.5 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 3.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 1.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.3 GO:0047611 tubulin deacetylase activity(GO:0042903) acetylspermidine deacetylase activity(GO:0047611)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 4.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.4 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.5 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.2 GO:0008252 nucleotidase activity(GO:0008252)
0.1 0.5 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.1 0.3 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.3 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 1.1 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.2 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.2 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 2.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 4.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 3.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.9 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.9 GO:0051020 GTPase binding(GO:0051020)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 3.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.0 0.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 2.6 GO:0042277 peptide binding(GO:0042277)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.7 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 3.6 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.2 2.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 1.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.9 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors