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PRJEB1986: zebrafish developmental stages transcriptome

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Results for prdm1a

Z-value: 1.10

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Transcription factors associated with prdm1a

Gene Symbol Gene ID Gene Info
prdm1a
ENSDARG00000002445 PR domain containing 1a, with ZNF domain

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prdm1adr11_v1_chr16_-_7443388_7443388-0.853.1e-06Click!

Activity profile of prdm1a motif

Sorted Z-values of prdm1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_1063988 3.45 ENSDART00000160400
gchfr
GTP cyclohydrolase I feedback regulator
chr18_+_8812549 3.08 ENSDART00000017619
impdh1a
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr23_-_21763598 2.75 ENSDART00000145408
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr12_-_4028079 2.70 ENSDART00000128676
si:ch211-180a12.2
si:ch211-180a12.2
chr16_-_50181206 2.68 ENSDART00000148478
lim2.5
lens intrinsic membrane protein 2.5
chr14_+_35806605 2.48 ENSDART00000173093
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr24_+_24923166 2.48 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr23_-_3703569 2.41 ENSDART00000143731
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr19_-_44955710 2.35 ENSDART00000165246
CSMD3 (1 of many)
si:ch211-233f16.1
chr8_-_14052349 2.30 ENSDART00000135811
atp2b3a
ATPase plasma membrane Ca2+ transporting 3a
chr16_-_9802998 2.30 ENSDART00000154217
tapbpl
TAP binding protein (tapasin)-like
chr8_+_16004154 2.24 ENSDART00000134787
ENSDART00000172510
ENSDART00000141173
elavl4
ELAV like neuron-specific RNA binding protein 4
chr11_+_21910343 2.21 ENSDART00000161485
foxp4
forkhead box P4
chr1_+_53377432 2.16 ENSDART00000177581
ucp1
uncoupling protein 1
chr24_-_39610585 2.07 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr6_-_8580857 2.06 ENSDART00000138858
ENSDART00000041142
myh11a
myosin, heavy chain 11a, smooth muscle
chr23_+_6232895 2.05 ENSDART00000139795
syt2a
synaptotagmin IIa
chr17_-_31058900 1.98 ENSDART00000134998
ENSDART00000104307
ENSDART00000172721
eml1
echinoderm microtubule associated protein like 1
chr15_-_47929455 1.95 ENSDART00000064462
psma6l
proteasome subunit alpha 6, like
chr13_-_21739142 1.95 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr20_+_4793790 1.90 ENSDART00000153486
lgals8a
galectin 8a
chr12_+_33038757 1.85 ENSDART00000153146
rbfox3a
RNA binding fox-1 homolog 3a
chr20_-_4793450 1.83 ENSDART00000053870
galca
galactosylceramidase a
chr9_-_5045378 1.69 ENSDART00000149268
nr4a2a
nuclear receptor subfamily 4, group A, member 2a
chr23_-_27123171 1.66 ENSDART00000023218
ENSDART00000146467
stat6
signal transducer and activator of transcription 6, interleukin-4 induced
chr5_-_17876709 1.61 ENSDART00000141978
si:dkey-112e17.1
si:dkey-112e17.1
chr5_-_64213253 1.60 ENSDART00000171711
gpsm1a
G protein signaling modulator 1a
chr20_+_49787584 1.58 ENSDART00000193458
ENSDART00000181511
ENSDART00000185850
ENSDART00000185613
ENSDART00000191671
CABZ01078261.1

chr15_+_40665310 1.58 ENSDART00000154187
ENSDART00000042082
fat3a
FAT atypical cadherin 3a
chr1_-_21599219 1.57 ENSDART00000148327
adamtsl7
ADAMTS-like 7
chr21_+_5169154 1.56 ENSDART00000102559
zgc:122979
zgc:122979
chr8_-_24135171 1.52 ENSDART00000112926
adora1b
adenosine A1 receptor b
chr5_+_51443009 1.49 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr17_+_5931530 1.46 ENSDART00000168326
ENSDART00000189790
znf513b
zinc finger protein 513b
chr3_-_59297532 1.43 ENSDART00000187991
CABZ01053748.1

chr10_+_17776981 1.42 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr4_-_17263210 1.41 ENSDART00000147853
lrmp
lymphoid-restricted membrane protein
chr10_-_45229877 1.41 ENSDART00000169281
pargl
poly (ADP-ribose) glycohydrolase, like
chr15_+_31886284 1.41 ENSDART00000156706
frya
furry homolog a (Drosophila)
chr9_-_19699728 1.41 ENSDART00000166780
si:ch211-141e20.2
si:ch211-141e20.2
chr5_-_12701603 1.35 ENSDART00000091124
aifm3
apoptosis-inducing factor, mitochondrion-associated, 3
chr14_+_45566074 1.35 ENSDART00000133477
ENSDART00000185899
zgc:92249
zgc:92249
chr8_+_2878756 1.34 ENSDART00000168107
crb2b
crumbs family member 2b
chr18_+_50275933 1.34 ENSDART00000143911
si:dkey-105e17.1
si:dkey-105e17.1
chr19_-_6774871 1.33 ENSDART00000170952
pvrl2l
poliovirus receptor-related 2 like
chr25_+_10416583 1.31 ENSDART00000073907
ehf
ets homologous factor
chr14_-_12837052 1.26 ENSDART00000165004
ENSDART00000043180
gria3b
glutamate receptor, ionotropic, AMPA 3b
chr1_-_54938137 1.25 ENSDART00000147212
crtac1a
cartilage acidic protein 1a
chr9_-_15208129 1.22 ENSDART00000137043
ENSDART00000131512
pard3bb
par-3 family cell polarity regulator beta b
chr17_+_39242437 1.20 ENSDART00000156138
ENSDART00000128863
zgc:174356
zgc:174356
chr9_-_19762801 1.17 ENSDART00000146841
si:ch211-141e20.2
si:ch211-141e20.2
chr2_-_43850637 1.17 ENSDART00000136077
zeb1a
zinc finger E-box binding homeobox 1a
chr20_+_715739 1.16 ENSDART00000136768
myo6a
myosin VIa
chr15_+_7992906 1.16 ENSDART00000090790
cadm2b
cell adhesion molecule 2b
chr16_+_5408748 1.15 ENSDART00000160008
ENSDART00000014024
plecb
plectin b
chr2_+_38608290 1.14 ENSDART00000159066
cdh24b
cadherin 24, type 2b
chr25_-_23745765 1.13 ENSDART00000089278
si:ch211-236l14.4
si:ch211-236l14.4
chr19_+_23296616 1.12 ENSDART00000134567
irgf1
immunity-related GTPase family, f1
chr19_-_36640677 1.08 ENSDART00000189743
csmd2
CUB and Sushi multiple domains 2
chr8_+_7737062 1.08 ENSDART00000166712
fgd1
FYVE, RhoGEF and PH domain containing 1
chr1_-_2457546 1.06 ENSDART00000103795
ggact.1
gamma-glutamylamine cyclotransferase, tandem duplicate 1
chr4_-_75869738 1.06 ENSDART00000170963
si:dkey-261j11.2
si:dkey-261j11.2
chr4_+_5132951 1.06 ENSDART00000103279
ccnd2b
cyclin D2, b
chr20_+_4793516 1.06 ENSDART00000053875
lgals8a
galectin 8a
chr13_-_43637371 1.06 ENSDART00000127930
ENSDART00000084474
fam160b1
family with sequence similarity 160, member B1
chr1_+_51903413 1.05 ENSDART00000135861
nfixa
nuclear factor I/Xa
chr3_-_24909245 1.04 ENSDART00000178321
SHISA8
shisa family member 8
chr3_+_16976095 1.04 ENSDART00000112450
cavin1a
caveolae associated protein 1a
chr19_+_9032073 1.04 ENSDART00000127755
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr10_+_38806719 1.03 ENSDART00000184416
dscama
Down syndrome cell adhesion molecule a
chr5_-_46980651 1.03 ENSDART00000181022
ENSDART00000168038
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr2_+_28995776 1.03 ENSDART00000138733
cdh12a
cadherin 12, type 2a (N-cadherin 2)
chr7_+_11197940 1.03 ENSDART00000081346
cemip
cell migration inducing protein, hyaluronan binding
chr4_+_25558849 1.02 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
zgc:195175
chr2_-_43850897 1.02 ENSDART00000005449
zeb1a
zinc finger E-box binding homeobox 1a
chr4_+_53268458 1.01 ENSDART00000165335
si:dkey-250k10.1
si:dkey-250k10.1
chr6_-_10780698 1.01 ENSDART00000151714
gpr155b
G protein-coupled receptor 155b
chr9_+_33158191 1.00 ENSDART00000180786
dopey2
dopey family member 2
chr5_+_70345518 0.99 ENSDART00000167029
pappaa
pregnancy-associated plasma protein A, pappalysin 1a
chr12_+_5190049 0.96 ENSDART00000126667
lgi1b
leucine-rich, glioma inactivated 1b
chr24_+_12945803 0.96 ENSDART00000005105
psme1
proteasome activator subunit 1
chr17_-_44968177 0.93 ENSDART00000075510
ngb
neuroglobin
chr5_-_26247671 0.93 ENSDART00000145187
erap1b
endoplasmic reticulum aminopeptidase 1b
chr18_-_6803424 0.92 ENSDART00000142647
si:dkey-266m15.5
si:dkey-266m15.5
chr18_-_12858016 0.91 ENSDART00000130343
parp12a
poly (ADP-ribose) polymerase family, member 12a
chr5_-_57723929 0.91 ENSDART00000144237
gig2p
grass carp reovirus (GCRV)-induced gene 2p
chr8_+_22491947 0.91 ENSDART00000125805
si:ch211-261n11.8
si:ch211-261n11.8
chr1_+_44710955 0.91 ENSDART00000131296
ENSDART00000142187
ssrp1b
structure specific recognition protein 1b
chr6_-_58149165 0.91 ENSDART00000170752
tox2
TOX high mobility group box family member 2
chr17_-_44968407 0.91 ENSDART00000165850
ngb
neuroglobin
chr12_+_20641471 0.90 ENSDART00000133654
calcoco2
calcium binding and coiled-coil domain 2
chr5_+_22406672 0.88 ENSDART00000141385
si:dkey-27p18.3
si:dkey-27p18.3
chr13_+_7578111 0.88 ENSDART00000175431
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr7_-_51627019 0.88 ENSDART00000174111
nhsl2
NHS-like 2
chr8_+_16004551 0.86 ENSDART00000165141
elavl4
ELAV like neuron-specific RNA binding protein 4
chr20_-_51399133 0.85 ENSDART00000151426
si:ch73-91k6.2
si:ch73-91k6.2
chr4_+_35130120 0.85 ENSDART00000192362
ENSDART00000181204
si:dkey-279j5.1
si:dkey-279j5.1
chr5_-_42904329 0.84 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr23_-_37835794 0.83 ENSDART00000137358
cd40
CD40 molecule, TNF receptor superfamily member 5
chr10_-_45230081 0.82 ENSDART00000169845
pargl
poly (ADP-ribose) glycohydrolase, like
chr16_-_51271962 0.82 ENSDART00000164021
ENSDART00000046420
serpinb1l1
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr1_+_31942961 0.82 ENSDART00000007522
anos1a
anosmin 1a
chr14_-_4121052 0.81 ENSDART00000167074
irf2
interferon regulatory factor 2
chr1_+_40034061 0.80 ENSDART00000011727
ccdc149b
coiled-coil domain containing 149b
chr11_-_29623380 0.80 ENSDART00000162587
ENSDART00000193935
ENSDART00000191646
chd5
chromodomain helicase DNA binding protein 5
chr17_+_25955003 0.78 ENSDART00000156029
grid1a
glutamate receptor, ionotropic, delta 1a
chr8_-_27858458 0.77 ENSDART00000132632
ENSDART00000136562
cttnbp2nlb
CTTNBP2 N-terminal like b
chr15_-_1003553 0.77 ENSDART00000154195
si:dkey-77f5.6
si:dkey-77f5.6
chr17_-_19784035 0.77 ENSDART00000190209
fmn2a
formin 2a
chr19_+_8612839 0.76 ENSDART00000144925
snx27a
sorting nexin family member 27a
chr18_+_50276337 0.75 ENSDART00000140352
si:dkey-105e17.1
si:dkey-105e17.1
chr12_+_20641102 0.75 ENSDART00000152964
calcoco2
calcium binding and coiled-coil domain 2
chr18_+_50276653 0.75 ENSDART00000192120
si:dkey-105e17.1
si:dkey-105e17.1
chr11_+_37144328 0.73 ENSDART00000162830
wnk2
WNK lysine deficient protein kinase 2
chr14_-_4120636 0.72 ENSDART00000059230
irf2
interferon regulatory factor 2
chr2_-_24369087 0.71 ENSDART00000081237
plvapa
plasmalemma vesicle associated protein a
chr24_+_26402110 0.71 ENSDART00000133684
si:ch211-230g15.5
si:ch211-230g15.5
chr5_-_60885935 0.70 ENSDART00000128350
rad51d
RAD51 paralog D
chr1_+_48256950 0.69 ENSDART00000171182
SORCS3
sortilin related VPS10 domain containing receptor 3
chr22_-_18164671 0.68 ENSDART00000014057
rfxank
regulatory factor X-associated ankyrin-containing protein
chr5_-_26247215 0.67 ENSDART00000136806
erap1b
endoplasmic reticulum aminopeptidase 1b
chr7_-_28148310 0.67 ENSDART00000044208
lmo1
LIM domain only 1
chr3_+_12593558 0.66 ENSDART00000186891
ENSDART00000159252
abca3b
ATP-binding cassette, sub-family A (ABC1), member 3b
chr1_-_55058795 0.64 ENSDART00000187293
peli1a
pellino E3 ubiquitin protein ligase 1a
chr21_+_5636008 0.64 ENSDART00000158385
shroom3
shroom family member 3
chr16_-_9383629 0.63 ENSDART00000084264
ENSDART00000166958
adcy2a
adenylate cyclase 2a
chr3_-_31833266 0.63 ENSDART00000084932
ENSDART00000183617
map3k3
mitogen-activated protein kinase kinase kinase 3
chr4_-_76370630 0.63 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr19_+_2275019 0.63 ENSDART00000136138
itgb8
integrin, beta 8
chr16_+_13898399 0.61 ENSDART00000140946
si:ch211-149k23.9
si:ch211-149k23.9
chr8_-_24730185 0.61 ENSDART00000113197
prok1
prokineticin 1
chr4_+_70967639 0.61 ENSDART00000159230
si:dkeyp-80d11.12
si:dkeyp-80d11.12
chr3_-_3019979 0.60 ENSDART00000111174
zgc:172090
zgc:172090
chr7_+_49695904 0.60 ENSDART00000183550
ENSDART00000126991
ascl1b
achaete-scute family bHLH transcription factor 1b
chr1_-_55131439 0.59 ENSDART00000074083
rab1aa
RAB1A, member RAS oncogene family a
chr1_+_10018466 0.57 ENSDART00000113551
trim2b
tripartite motif containing 2b
chr14_-_1543834 0.57 ENSDART00000185876
CABZ01109480.1

chr20_-_13394780 0.56 ENSDART00000063816
kcnk3a
potassium channel, subfamily K, member 3a
chr22_-_8509215 0.56 ENSDART00000140146
si:ch73-27e22.3
si:ch73-27e22.3
chr7_+_5908077 0.56 ENSDART00000173404
hist1h2a4
histone cluster 1 H2A family member 4
chr22_-_23253252 0.56 ENSDART00000175556
lhx9
LIM homeobox 9
chr21_+_20356458 0.56 ENSDART00000135816
pde6b
phosphodiesterase 6B, cGMP-specific, rod, beta
chr13_-_50234122 0.56 ENSDART00000164338
eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
chr15_-_36347858 0.55 ENSDART00000155274
ENSDART00000157936
si:dkey-23k10.2
si:dkey-23k10.2
chr13_-_9335891 0.54 ENSDART00000080637
BX901922.1

chr5_-_26247973 0.52 ENSDART00000098527
erap1b
endoplasmic reticulum aminopeptidase 1b
chr12_+_5189776 0.52 ENSDART00000081298
lgi1b
leucine-rich, glioma inactivated 1b
chr20_-_25412181 0.52 ENSDART00000062780
itsn2a
intersectin 2a
chr9_+_46745348 0.50 ENSDART00000025256
igfbp2b
insulin-like growth factor binding protein 2b
chr22_-_18164835 0.49 ENSDART00000143189
rfxank
regulatory factor X-associated ankyrin-containing protein
chr5_+_32007627 0.49 ENSDART00000183061
scai
suppressor of cancer cell invasion
chr19_-_7115229 0.48 ENSDART00000001930
psmb13a
proteasome subunit beta 13a
chr11_-_38492564 0.48 ENSDART00000102850
elk4
ELK4, ETS-domain protein
chr21_-_31143903 0.48 ENSDART00000111571
rap1gap2b
RAP1 GTPase activating protein 2b
chr4_-_76239517 0.47 ENSDART00000172599
si:ch211-106j21.6
si:ch211-106j21.6
chr4_-_46915024 0.46 ENSDART00000169913
si:ch211-134c10.1
si:ch211-134c10.1
chr24_+_10202718 0.43 ENSDART00000126668
pou6f2
POU class 6 homeobox 2
chr8_-_19051906 0.42 ENSDART00000089024
sema6bb
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb
chr4_-_76129431 0.42 ENSDART00000162809
si:ch211-106j21.2
si:ch211-106j21.2
chr4_-_75616197 0.41 ENSDART00000157778
si:dkey-71l4.3
si:dkey-71l4.3
chr4_-_76027176 0.40 ENSDART00000165718
si:dkey-71l4.1
si:dkey-71l4.1
chr23_+_43870886 0.40 ENSDART00000102658
ENSDART00000149088
nfxl1
nuclear transcription factor, X-box binding-like 1
chr11_-_34628789 0.38 ENSDART00000192433
mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr18_+_47313715 0.37 ENSDART00000138806
barx2
BARX homeobox 2
chr20_-_26929685 0.35 ENSDART00000132556
ftr79
finTRIM family, member 79
chr7_-_3693536 0.35 ENSDART00000126381
si:ch211-282j17.13
si:ch211-282j17.13
chr23_+_33718602 0.34 ENSDART00000024695
dazap2
DAZ associated protein 2
chr6_-_19271210 0.32 ENSDART00000163628
ENSDART00000159124
zgc:174863
zgc:174863
chr3_-_1859198 0.32 ENSDART00000121870
micall1b.2
MICAL like 1b, duplicate 2
chr6_+_29861288 0.31 ENSDART00000166782
dlg1
discs, large homolog 1 (Drosophila)
chr18_-_16792561 0.30 ENSDART00000145546
ampd3b
adenosine monophosphate deaminase 3b
chr1_+_20069535 0.30 ENSDART00000088653
prss12
protease, serine, 12 (neurotrypsin, motopsin)
chr4_-_37696010 0.29 ENSDART00000169984
si:dkey-3p4.1
si:dkey-3p4.1
chr4_-_31699842 0.28 ENSDART00000166400
si:dkey-265e15.5
si:dkey-265e15.5
chr4_-_75511162 0.28 ENSDART00000157651
si:dkey-71l4.5
si:dkey-71l4.5
chr7_+_27251376 0.28 ENSDART00000173521
ENSDART00000173962
sox6
SRY (sex determining region Y)-box 6
chr4_-_22338906 0.27 ENSDART00000131402
golgb1
golgin B1
chr22_+_5858467 0.27 ENSDART00000137295
si:dkey-222f2.7
si:dkey-222f2.7
chr18_+_14693682 0.27 ENSDART00000132249
uri1
URI1, prefoldin-like chaperone
chr7_+_854237 0.26 ENSDART00000181029
zgc:175177
zgc:175177
chr12_-_37299646 0.25 ENSDART00000146142
ENSDART00000085201
pmp22b
peripheral myelin protein 22b
chr4_+_68591587 0.25 ENSDART00000189881
ENSDART00000162142
si:dkey-16p6.1
si:dkey-16p6.1
chr16_-_9802449 0.25 ENSDART00000081208
tapbpl
TAP binding protein (tapasin)-like
chr3_-_22366562 0.24 ENSDART00000129447
ifnphi1
interferon phi 1
chr17_-_29902187 0.23 ENSDART00000009104
esrrb
estrogen-related receptor beta
chr3_+_47322494 0.23 ENSDART00000102202
ppap2d
phosphatidic acid phosphatase type 2D
chr11_-_26040594 0.23 ENSDART00000144115
kaznb
kazrin, periplakin interacting protein b
chr1_+_31706668 0.21 ENSDART00000057879
as3mt
arsenite methyltransferase
chr15_+_38025319 0.20 ENSDART00000155000
si:ch73-380l3.3
si:ch73-380l3.3
chr5_-_64103863 0.20 ENSDART00000135014
ENSDART00000083684
pappab
pregnancy-associated plasma protein A, pappalysin 1b
chr3_-_10739625 0.19 ENSDART00000156144
zgc:112965
zgc:112965
chr25_-_30357027 0.19 ENSDART00000171137
pdia3
protein disulfide isomerase family A, member 3
chr4_-_75615597 0.19 ENSDART00000187794
si:dkey-71l4.3
si:dkey-71l4.3
chr1_-_8966046 0.19 ENSDART00000136198
socs1b
suppressor of cytokine signaling 1b
chr4_-_75641117 0.18 ENSDART00000182165
si:dkey-71l4.2
si:dkey-71l4.2
chr6_+_24661736 0.17 ENSDART00000169283
znf644b
zinc finger protein 644b
chr4_+_70911498 0.17 ENSDART00000157674
si:dkey-16p6.1
si:dkey-16p6.1
chr24_-_20915050 0.16 ENSDART00000133763
si:ch211-161h7.5
si:ch211-161h7.5
chr4_+_29702703 0.16 ENSDART00000167771
si:ch211-214c20.1
si:ch211-214c20.1
chr22_-_34995333 0.15 ENSDART00000110900
kcnip2
Kv channel interacting protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of prdm1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0035046 pronuclear migration(GO:0035046)
0.4 2.2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.4 4.7 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 2.8 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.3 3.1 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.3 1.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.3 1.7 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.3 0.8 GO:0035666 response to protozoan(GO:0001562) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) defense response to protozoan(GO:0042832) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.3 2.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.3 1.3 GO:0061439 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2 1.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 2.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.2 1.7 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 0.6 GO:0097376 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.2 2.0 GO:0036368 cone photoresponse recovery(GO:0036368)
0.2 0.7 GO:0042148 strand invasion(GO:0042148)
0.1 1.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 1.0 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.6 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 2.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.0 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 3.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.4 GO:0097320 membrane tubulation(GO:0097320)
0.1 1.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 2.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.8 GO:0015671 oxygen transport(GO:0015671)
0.1 0.9 GO:2000403 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.1 0.2 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 1.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 2.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 2.2 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.1 0.8 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 1.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 1.3 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.7 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.8 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 1.6 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 1.0 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 1.4 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 4.5 GO:0051346 negative regulation of hydrolase activity(GO:0051346)
0.0 1.5 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.6 GO:0001843 neural tube closure(GO:0001843)
0.0 0.1 GO:0002836 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of mast cell activation(GO:0033005) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 1.9 GO:0050673 epithelial cell proliferation(GO:0050673)
0.0 0.9 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.5 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.0 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.9 GO:1902275 regulation of chromatin organization(GO:1902275)
0.0 0.6 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 2.9 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.8 GO:0045010 actin nucleation(GO:0045010)
0.0 0.6 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 2.3 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 1.0 GO:0008537 proteasome activator complex(GO:0008537)
0.1 2.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.7 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.0 GO:0016586 RSC complex(GO:0016586)
0.1 1.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 4.9 GO:0043204 perikaryon(GO:0043204)
0.1 3.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.9 GO:0035101 FACT complex(GO:0035101)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 2.2 GO:0016342 catenin complex(GO:0016342)
0.0 3.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 5.8 GO:0005912 adherens junction(GO:0005912)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.4 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.9 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.5 2.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 3.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 2.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 1.8 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 1.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 3.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 1.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.8 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.2 0.6 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.2 1.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 2.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 2.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 1.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.6 GO:0051087 chaperone binding(GO:0051087)
0.0 1.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.8 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.0 GO:0045296 cadherin binding(GO:0045296)
0.0 2.5 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0070330 aromatase activity(GO:0070330)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.6 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 2.8 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 2.1 GO:0003774 motor activity(GO:0003774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 4.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 0.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators