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PRJEB1986: zebrafish developmental stages transcriptome

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Results for prdm4

Z-value: 0.55

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Transcription factors associated with prdm4

Gene Symbol Gene ID Gene Info
prdm4
ENSDARG00000017366 PR domain containing 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prdm4dr11_v1_chr4_-_14926106_14926106-0.742.9e-04Click!

Activity profile of prdm4 motif

Sorted Z-values of prdm4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_15893093 2.40 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
si:dkey-14o1.20
chr9_-_13355071 1.84 ENSDART00000084055
fzd7a
frizzled class receptor 7a
chr17_-_31611692 1.75 ENSDART00000141480
si:dkey-170l10.1
si:dkey-170l10.1
chr3_+_31621774 1.66 ENSDART00000076636
fzd2
frizzled class receptor 2
chr22_-_21046654 1.10 ENSDART00000064902
ssbp4
single stranded DNA binding protein 4
chr23_-_24682244 1.07 ENSDART00000104035
ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr22_-_21046843 0.98 ENSDART00000133982
ssbp4
single stranded DNA binding protein 4
chr10_-_3332362 0.92 ENSDART00000007577
ENSDART00000055140
tor4aa
torsin family 4, member Aa
chr21_-_37027252 0.88 ENSDART00000076483
zgc:77151
zgc:77151
chr9_+_41690153 0.81 ENSDART00000100226
ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr6_-_9707599 0.77 ENSDART00000039280
fzd7b
frizzled class receptor 7b
chr3_+_25999477 0.65 ENSDART00000024316
mcm5
minichromosome maintenance complex component 5
chr17_+_31611854 0.61 ENSDART00000011706
adprhl2
ADP-ribosylhydrolase like 2
chr5_+_27442247 0.60 ENSDART00000184129
loxl2b
lysyl oxidase-like 2b
chr24_-_27409599 0.60 ENSDART00000041770
ccl34b.3
chemokine (C-C motif) ligand 34b, duplicate 3
chr1_+_56180416 0.53 ENSDART00000089358
crb3b
crumbs homolog 3b
chr24_+_29912509 0.44 ENSDART00000168422
frrs1b
ferric-chelate reductase 1b
chr19_+_2670130 0.32 ENSDART00000152152
si:ch73-24k9.2
si:ch73-24k9.2
chr11_-_6868474 0.26 ENSDART00000168372
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr9_+_22359919 0.12 ENSDART00000009591
crygs4
crystallin, gamma S4
chr11_-_6868287 0.12 ENSDART00000037824
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr3_+_40407352 0.10 ENSDART00000155112
tnrc18
trinucleotide repeat containing 18
chr1_+_12348213 0.00 ENSDART00000144920
ENSDART00000138759
ENSDART00000067082
clta
clathrin, light chain A

Network of associatons between targets according to the STRING database.

First level regulatory network of prdm4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.4 1.8 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 0.6 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.6 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.4 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.8 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.6 GO:0010008 endosome membrane(GO:0010008)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.6 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease