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PRJEB1986: zebrafish developmental stages transcriptome

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Results for rarga

Z-value: 1.42

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Transcription factors associated with rarga

Gene Symbol Gene ID Gene Info
rarga
ENSDARG00000034117 retinoic acid receptor gamma a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rargadr11_v1_chr23_+_35847200_358472000.503.0e-02Click!

Activity profile of rarga motif

Sorted Z-values of rarga motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_40856534 9.57 ENSDART00000051950
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr19_+_40856807 9.04 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr7_+_15266093 3.33 ENSDART00000124676
sv2ba
synaptic vesicle glycoprotein 2Ba
chr10_-_39321367 3.13 ENSDART00000129647
smtlb
somatolactin beta
chr13_-_22862133 2.98 ENSDART00000138563
pbld2
phenazine biosynthesis-like protein domain containing 2
chr16_+_48753664 2.96 ENSDART00000155148
si:ch73-31d8.2
si:ch73-31d8.2
chr8_-_25329967 2.51 ENSDART00000139682
eps8l3b
EPS8-like 3b
chr25_+_3326885 2.51 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr23_+_24789205 2.48 ENSDART00000088697
olfml3a
olfactomedin-like 3a
chr15_+_19682013 2.46 ENSDART00000127368
si:dkey-4p15.5
si:dkey-4p15.5
chr14_-_33454595 2.42 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr6_+_41099787 2.40 ENSDART00000186884
fkbp5
FK506 binding protein 5
chr19_+_5072918 2.31 ENSDART00000037126
eno2
enolase 2
chr14_+_6159162 2.29 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr19_-_42424599 2.25 ENSDART00000077042
zgc:153441
zgc:153441
chr24_-_17029374 2.22 ENSDART00000039267
ptgdsb.1
prostaglandin D2 synthase b, tandem duplicate 1
chr7_+_20344486 2.20 ENSDART00000134004
ENSDART00000139685
ponzr1
plac8 onzin related protein 1
chr6_+_48618512 2.09 ENSDART00000111190
FAM19A3
si:dkey-238f9.1
chr24_-_17047918 2.04 ENSDART00000020204
msrb2
methionine sulfoxide reductase B2
chr1_-_22726233 2.02 ENSDART00000140920
prom1b
prominin 1 b
chr10_-_27046639 1.97 ENSDART00000041841
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr10_-_24648228 1.92 ENSDART00000081834
ENSDART00000132830
stoml3b
stomatin (EPB72)-like 3b
chr19_-_703898 1.92 ENSDART00000181096
ENSDART00000121462
slc6a19a.2
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr2_-_42234484 1.89 ENSDART00000132617
ENSDART00000136690
ENSDART00000141358
apom
apolipoprotein M
chr14_-_36412473 1.77 ENSDART00000128244
ENSDART00000138376
asb5a
ankyrin repeat and SOCS box containing 5a
chr11_-_24681292 1.76 ENSDART00000089601
olfml3b
olfactomedin-like 3b
chr15_+_19681718 1.75 ENSDART00000164803
si:dkey-4p15.5
si:dkey-4p15.5
chr20_+_6142433 1.75 ENSDART00000054084
ENSDART00000136986
ttr
transthyretin (prealbumin, amyloidosis type I)
chr13_-_22843562 1.74 ENSDART00000142738
pbld
phenazine biosynthesis like protein domain containing
chr25_+_3327071 1.72 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr21_-_20939488 1.71 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr8_+_19514294 1.67 ENSDART00000170622
si:ch73-281k2.5
si:ch73-281k2.5
chr6_-_49898881 1.66 ENSDART00000150204
atp5f1e
ATP synthase F1 subunit epsilon
chr20_+_9128829 1.65 ENSDART00000064144
ENSDART00000137450
bpnt1
bisphosphate nucleotidase 1
chr20_-_14665002 1.64 ENSDART00000152816
scrn2
secernin 2
chr13_+_22264914 1.60 ENSDART00000060576
myoz1a
myozenin 1a
chr4_-_17409533 1.59 ENSDART00000011943
pah
phenylalanine hydroxylase
chr10_-_29120515 1.57 ENSDART00000162016
ENSDART00000149140
zpld1a
zona pellucida-like domain containing 1a
chr12_+_46605600 1.48 ENSDART00000123533
FADS6
fatty acid desaturase 6
chr8_+_22851472 1.43 ENSDART00000041564
cacna1fb
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr2_-_24289641 1.42 ENSDART00000128784
ENSDART00000123565
ENSDART00000141922
ENSDART00000184550
ENSDART00000191469
myh7l
myosin heavy chain 7-like
chr22_-_18779232 1.41 ENSDART00000186726
atp5f1d
ATP synthase F1 subunit delta
chr20_+_16750177 1.38 ENSDART00000185357
calm1b
calmodulin 1b
chr2_+_51028269 1.38 ENSDART00000161254
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr2_+_24868010 1.34 ENSDART00000078838
rab3aa
RAB3A, member RAS oncogene family, a
chr9_-_44939104 1.34 ENSDART00000192903
vil1
villin 1
chr25_-_19090479 1.32 ENSDART00000027465
ENSDART00000177670
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr1_-_46632948 1.25 ENSDART00000148893
ENSDART00000053232
cdadc1
cytidine and dCMP deaminase domain containing 1
chr6_+_52235441 1.24 ENSDART00000056319
cox6c
cytochrome c oxidase subunit VIc
chr1_+_34763539 1.22 ENSDART00000077725
ENSDART00000113808
zgc:172122
zgc:172122
chr18_-_22753637 1.15 ENSDART00000181589
ENSDART00000009912
hsf4
heat shock transcription factor 4
chr22_-_18778988 1.13 ENSDART00000019235
atp5f1d
ATP synthase F1 subunit delta
chr22_+_27284462 1.09 ENSDART00000164660
si:ch73-103b2.1
si:ch73-103b2.1
chr7_+_16033923 1.09 ENSDART00000161669
ENSDART00000114062
immp1l
inner mitochondrial membrane peptidase subunit 1
chr5_+_69868911 1.09 ENSDART00000014649
ENSDART00000188215
ENSDART00000167385
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr12_+_4573696 1.07 ENSDART00000152534
si:dkey-94f20.4
si:dkey-94f20.4
chr19_-_30404096 1.06 ENSDART00000103475
agr2
anterior gradient 2
chr5_+_42467867 1.03 ENSDART00000172028
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr7_-_16205471 1.02 ENSDART00000173584
btr05
bloodthirsty-related gene family, member 5
chr9_+_31795343 1.02 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr13_+_15182149 1.02 ENSDART00000193644
ENSDART00000134421
ENSDART00000086281
mavs
mitochondrial antiviral signaling protein
chr6_+_28054639 1.01 ENSDART00000187478
ENSDART00000189194
si:ch73-194h10.2
si:ch73-194h10.2
chr10_-_25543227 1.00 ENSDART00000007778
grik1a
glutamate receptor, ionotropic, kainate 1a
chr18_-_42172101 0.99 ENSDART00000124211
cntn5
contactin 5
chr20_+_23960525 0.98 ENSDART00000042123
cx52.6
connexin 52.6
chr19_-_103289 0.96 ENSDART00000143118
adgrb1b
adhesion G protein-coupled receptor B1b
chr15_-_30815826 0.95 ENSDART00000156160
ENSDART00000145918
msi2b
musashi RNA-binding protein 2b
chr4_+_9836465 0.94 ENSDART00000004879
hsp90b1
heat shock protein 90, beta (grp94), member 1
chr5_-_9090178 0.93 ENSDART00000091472
kcnv2b
potassium channel, subfamily V, member 2b
chr23_+_42336084 0.93 ENSDART00000158959
ENSDART00000161812
cyp2aa7
cyp2aa8
cytochrome P450, family 2, subfamily AA, polypeptide 7
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr24_-_25256230 0.93 ENSDART00000155780
hhla2b.1
HERV-H LTR-associating 2b, tandem duplicate 1
chr13_+_22480857 0.92 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
ldb3a
LIM domain binding 3a
chr24_+_33802528 0.91 ENSDART00000136040
ENSDART00000147499
ENSDART00000182322
atg9b
autophagy related 9B
chr12_+_46708920 0.91 ENSDART00000153089
exoc7
exocyst complex component 7
chr21_+_40225915 0.90 ENSDART00000048475
ENSDART00000174122
or115-12
odorant receptor, family F, subfamily 115, member 12
chr7_+_20344222 0.89 ENSDART00000141186
ENSDART00000139274
ponzr1
plac8 onzin related protein 1
chr1_+_54626491 0.88 ENSDART00000136063
si:ch211-202h22.9
si:ch211-202h22.9
chr3_-_15080226 0.87 ENSDART00000109818
ENSDART00000139835
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr7_-_50883433 0.85 ENSDART00000174314
PAQR9
progestin and adipoQ receptor family member 9
chr9_-_34871900 0.84 ENSDART00000026378
slc25a6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr25_+_31929325 0.84 ENSDART00000181095
apba2a
amyloid beta (A4) precursor protein-binding, family A, member 2a
chr21_-_22831388 0.82 ENSDART00000151040
angptl5
angiopoietin-like 5
chr19_-_5103141 0.80 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr19_-_5103313 0.80 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr1_-_58913813 0.80 ENSDART00000056494
zgc:171687
zgc:171687
chr19_+_30867845 0.79 ENSDART00000047461
mfsd2ab
major facilitator superfamily domain containing 2ab
chr25_-_26018424 0.79 ENSDART00000089332
acsbg1
acyl-CoA synthetase bubblegum family member 1
chr19_-_30403922 0.79 ENSDART00000181841
agr2
anterior gradient 2
chr18_-_1185772 0.78 ENSDART00000143245
nptnb
neuroplastin b
chr7_-_56793739 0.78 ENSDART00000082842
si:ch211-146m13.3
si:ch211-146m13.3
chr2_+_38264964 0.78 ENSDART00000182068
dhrs1
dehydrogenase/reductase (SDR family) member 1
chr10_-_16028082 0.78 ENSDART00000122540
aldh7a1
aldehyde dehydrogenase 7 family, member A1
chr10_-_15963903 0.77 ENSDART00000142357
si:dkey-3h23.3
si:dkey-3h23.3
chr16_+_50741154 0.77 ENSDART00000101627
IGLON5
zgc:110372
chr11_-_19097746 0.76 ENSDART00000103973
rhol
rhodopsin, like
chr7_+_20344032 0.76 ENSDART00000144948
ENSDART00000138786
ponzr1
plac8 onzin related protein 1
chr8_+_668184 0.76 ENSDART00000183788
rnf165b
ring finger protein 165b
chr9_-_48397702 0.75 ENSDART00000147169
zgc:172182
zgc:172182
chr2_-_53592532 0.74 ENSDART00000184066
ccl25a
chemokine (C-C motif) ligand 25a
chr21_+_15723069 0.74 ENSDART00000149126
ENSDART00000130628
p2rx4a
purinergic receptor P2X, ligand-gated ion channel, 4a
chr15_-_24883956 0.72 ENSDART00000113199
aipl1
aryl hydrocarbon receptor interacting protein-like 1
chr2_+_7818368 0.71 ENSDART00000007068
kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr2_-_22230326 0.71 ENSDART00000127810
fam110b
family with sequence similarity 110, member B
chr16_-_17116499 0.69 ENSDART00000138983
si:dkey-260g12.1
si:dkey-260g12.1
chr2_-_27774783 0.68 ENSDART00000161864
XKR4
zgc:123035
chr14_+_51015205 0.67 ENSDART00000074216
higd2a
HIG1 hypoxia inducible domain family, member 2A
chr11_+_37201483 0.67 ENSDART00000160930
ENSDART00000173439
ENSDART00000171273
zgc:112265
zgc:112265
chr13_+_22480496 0.67 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr14_+_30795559 0.66 ENSDART00000006132
cfl1
cofilin 1
chr15_+_3284416 0.66 ENSDART00000187665
ENSDART00000171723
foxo1a
forkhead box O1 a
chr16_+_27345383 0.65 ENSDART00000078250
ENSDART00000162857
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr8_+_48095911 0.64 ENSDART00000138717
si:ch211-263k4.2
si:ch211-263k4.2
chr17_-_51224800 0.63 ENSDART00000150089
psen1
presenilin 1
chr11_+_3578543 0.60 ENSDART00000191015
si:dkey-33m11.8
si:dkey-33m11.8
chr2_-_34483597 0.59 ENSDART00000133224
brinp2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr21_-_30658509 0.59 ENSDART00000139764
si:dkey-22f5.9
si:dkey-22f5.9
chr24_-_10828560 0.59 ENSDART00000132282
fam49bb
family with sequence similarity 49, member Bb
chr25_-_19661198 0.58 ENSDART00000149641
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr19_+_30387999 0.58 ENSDART00000145396
tspan13b
tetraspanin 13b
chr4_-_13567387 0.56 ENSDART00000132971
ENSDART00000102010
mdm1
Mdm1 nuclear protein homolog (mouse)
chr13_-_9119867 0.56 ENSDART00000137255
si:dkey-112g5.15
si:dkey-112g5.15
chr24_-_11309477 0.56 ENSDART00000137257
myrip
myosin VIIA and Rab interacting protein
chr3_+_62356578 0.55 ENSDART00000157030
iqck
IQ motif containing K
chr5_-_55933420 0.54 ENSDART00000050966
slc25a46
solute carrier family 25, member 46
chr2_-_31634978 0.54 ENSDART00000135668
si:ch211-106h4.9
si:ch211-106h4.9
chr17_-_32370047 0.54 ENSDART00000145487
klf11b
Kruppel-like factor 11b
chr14_+_46216703 0.53 ENSDART00000136045
ENSDART00000142317
mgst2
microsomal glutathione S-transferase 2
chr5_+_30179010 0.53 ENSDART00000134624
adamts15a
ADAM metallopeptidase with thrombospondin type 1 motif, 15a
chr13_-_37254777 0.52 ENSDART00000139734
syne2b
spectrin repeat containing, nuclear envelope 2b
chr15_-_43768776 0.52 ENSDART00000170398
grm5b
glutamate receptor, metabotropic 5b
chr6_-_10835849 0.51 ENSDART00000005903
ENSDART00000135065
atp5mc3b
ATP synthase membrane subunit c locus 3b
chr14_-_44841335 0.50 ENSDART00000173011
GRXCR1
si:dkey-109l4.6
chr6_-_10912424 0.50 ENSDART00000036456
cycsb
cytochrome c, somatic b
chr3_-_25369557 0.50 ENSDART00000055491
smurf2
SMAD specific E3 ubiquitin protein ligase 2
chr5_-_55395964 0.49 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr11_-_40257225 0.49 ENSDART00000139009
TRIM62 (1 of many)
si:ch211-193i15.2
chr19_-_8732037 0.48 ENSDART00000138971
si:ch211-39a7.1
si:ch211-39a7.1
chr24_-_20808283 0.47 ENSDART00000143759
vipr1b
vasoactive intestinal peptide receptor 1b
chr3_+_29458517 0.47 ENSDART00000134258
grap2a
GRB2-related adaptor protein 2a
chr8_+_37905666 0.46 ENSDART00000145067
prlhr2a
prolactin releasing hormone receptor 2a
chr4_-_17629444 0.46 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr14_-_44841503 0.45 ENSDART00000179114
GRXCR1
si:dkey-109l4.6
chr6_+_18569453 0.45 ENSDART00000171338
rhot1b
ras homolog family member T1
chr12_-_13318944 0.44 ENSDART00000152201
ENSDART00000041394
emc9
ER membrane protein complex subunit 9
chr1_-_55118745 0.41 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr23_-_27506161 0.40 ENSDART00000145007
asb8
ankyrin repeat and SOCS box containing 8
chr21_-_29100110 0.40 ENSDART00000142598
timd4
T cell immunoglobulin and mucin domain containing 4
chr5_+_13243446 0.39 ENSDART00000186140
CR933528.1

chr7_-_16237861 0.39 ENSDART00000173647
btr07
bloodthirsty-related gene family, member 7
chr2_-_22286828 0.39 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr5_-_64168415 0.39 ENSDART00000048395
cmlc1
cardiac myosin light chain-1
chr6_+_52804267 0.39 ENSDART00000065681
matn4
matrilin 4
chr22_-_1079773 0.38 ENSDART00000136668
si:ch1073-15f12.3
si:ch1073-15f12.3
chr7_-_27033080 0.38 ENSDART00000173516
nucb2a
nucleobindin 2a
chr20_-_25709247 0.37 ENSDART00000146711
si:dkeyp-117h8.2
si:dkeyp-117h8.2
chr7_+_52122224 0.37 ENSDART00000174268
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr18_-_14937211 0.37 ENSDART00000141893
mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr24_-_25363815 0.37 ENSDART00000186814
ptchd1
patched domain containing 1
chr21_+_37355716 0.37 ENSDART00000131188
nsd1b
nuclear receptor binding SET domain protein 1b
chr8_+_41712799 0.37 ENSDART00000150337
si:ch211-208g1.1
si:ch211-208g1.1
chr3_-_1364946 0.36 ENSDART00000159328
FP236551.1

chr25_-_16826219 0.36 ENSDART00000191299
ENSDART00000188504
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr7_+_52135791 0.35 ENSDART00000098705
cyp2x12
cytochrome P450, family 2, subfamily X, polypeptide 12
chr3_-_62393449 0.35 ENSDART00000101870
ENSDART00000140782
ENSDART00000181704
proza
protein Z, vitamin K-dependent plasma glycoprotein a
chr2_+_38608290 0.35 ENSDART00000159066
cdh24b
cadherin 24, type 2b
chr20_+_11800063 0.34 ENSDART00000152230
si:ch211-155o21.4
si:ch211-155o21.4
chr8_+_24740013 0.33 ENSDART00000126897
lamtor5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr17_-_12196865 0.33 ENSDART00000154694
kif28
kinesin family member 28
chr3_-_3210640 0.32 ENSDART00000187699
si:ch211-229i14.2
si:ch211-229i14.2
chr4_+_8680767 0.32 ENSDART00000182726
adipor2
adiponectin receptor 2
chr15_-_37752236 0.32 ENSDART00000154263
si:dkey-42l23.5
si:dkey-42l23.5
chr21_+_28724099 0.31 ENSDART00000138017
puraa
purine-rich element binding protein Aa
chr8_+_22472584 0.31 ENSDART00000138303
si:dkey-23c22.9
si:dkey-23c22.9
chr12_+_38983989 0.31 ENSDART00000156673
si:ch73-181m17.1
si:ch73-181m17.1
chr2_+_24536762 0.31 ENSDART00000144149
angptl4
angiopoietin-like 4
chr1_+_54043563 0.31 ENSDART00000149760
triobpa
TRIO and F-actin binding protein a
chr21_-_551014 0.31 ENSDART00000099252
vimr1
vimentin-related 1
chr11_+_43363075 0.30 ENSDART00000179934
CU929458.1

chr23_-_19953089 0.30 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr1_+_48256950 0.30 ENSDART00000171182
SORCS3
sortilin related VPS10 domain containing receptor 3
chr5_-_35301800 0.29 ENSDART00000085142
map1b
microtubule-associated protein 1B
chr12_-_30583668 0.29 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr7_-_58729894 0.29 ENSDART00000149347
chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr18_-_42333428 0.28 ENSDART00000034225
cntn5
contactin 5
chr21_+_5801105 0.28 ENSDART00000151225
ENSDART00000184487
ccng2
cyclin G2
chr21_-_40557281 0.28 ENSDART00000172327
taok1b
TAO kinase 1b
chr5_-_41531629 0.27 ENSDART00000051082
akr1a1a
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr15_-_20933574 0.27 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
usp2a
ubiquitin specific peptidase 2a
chr7_+_20512419 0.27 ENSDART00000173907
si:dkey-19b23.14
si:dkey-19b23.14
chr16_-_7228276 0.27 ENSDART00000149030
nt5c3a
5'-nucleotidase, cytosolic IIIA
chr6_-_20952187 0.26 ENSDART00000074327
igfbp2a
insulin-like growth factor binding protein 2a
chr7_-_63637644 0.26 ENSDART00000145168
si:ch211-208g1.1
si:ch211-208g1.1
chr17_+_33495194 0.24 ENSDART00000033691
pth2
parathyroid hormone 2
chr7_-_42206720 0.24 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr7_+_34506937 0.24 ENSDART00000111303
rfx7a
regulatory factor X7a
chr21_-_21527983 0.24 ENSDART00000014254
diablob
diablo, IAP-binding mitochondrial protein b
chr25_+_22571475 0.23 ENSDART00000161559
stra6
stimulated by retinoic acid 6
chr18_+_13315739 0.23 ENSDART00000143404
si:ch211-260p9.3
si:ch211-260p9.3
chr22_-_17953529 0.22 ENSDART00000135716
ncanb
neurocan b
chr8_+_20679759 0.22 ENSDART00000088668
nfic
nuclear factor I/C

Network of associatons between targets according to the STRING database.

First level regulatory network of rarga

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0030091 protein repair(GO:0030091)
0.4 1.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.4 2.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 1.6 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 1.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 3.8 GO:0072078 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.3 1.3 GO:0072673 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.3 2.3 GO:0034389 lipid particle organization(GO:0034389)
0.3 2.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.3 1.4 GO:0043029 T cell homeostasis(GO:0043029)
0.3 3.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.2 0.7 GO:0072679 thymocyte migration(GO:0072679)
0.2 1.0 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.2 0.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 0.8 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.2 1.0 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.2 4.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 0.5 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 0.7 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 1.7 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 0.8 GO:0045056 transcytosis(GO:0045056)
0.2 0.9 GO:0035889 otolith tethering(GO:0035889)
0.2 1.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 1.5 GO:0072337 modified amino acid transport(GO:0072337)
0.1 1.6 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.7 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.5 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.7 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.9 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.3 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.9 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461) vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.1 1.7 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 0.6 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 2.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 2.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.4 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 0.7 GO:0033198 response to ATP(GO:0033198)
0.1 1.0 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.2 GO:0046184 aldehyde biosynthetic process(GO:0046184)
0.1 2.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.9 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.5 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.1 GO:0002456 T cell cytokine production(GO:0002369) T cell mediated immunity(GO:0002456)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.1 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.3 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.4 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 1.0 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.6 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.8 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.5 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.0 1.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.3 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.3 GO:0001840 neural plate development(GO:0001840)
0.0 1.4 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 1.2 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.5 GO:0090148 membrane fission(GO:0090148)
0.0 1.8 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.6 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 18.4 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.4 GO:0050890 cognition(GO:0050890)
0.0 0.6 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 18.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.0 4.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.3 2.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.3 GO:0032433 filopodium tip(GO:0032433)
0.3 2.0 GO:0071914 prominosome(GO:0071914)
0.2 1.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 1.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.1 2.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 2.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 1.0 GO:0008305 integrin complex(GO:0008305)
0.0 1.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 5.9 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.9 18.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.6 4.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.6 2.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.5 2.0 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.4 1.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 1.6 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.4 4.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 1.6 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.3 2.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 2.2 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.8 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.2 1.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 1.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.2 1.6 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.5 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.0 GO:0016918 retinal binding(GO:0016918)
0.1 1.9 GO:0008252 nucleotidase activity(GO:0008252)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.5 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 1.7 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.8 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.5 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 4.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.8 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 1.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 3.3 GO:0016853 isomerase activity(GO:0016853)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.7 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.2 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 1.8 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 18.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 18.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 1.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives