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PRJEB1986: zebrafish developmental stages transcriptome

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Results for rfx3_rfx2+rfx4

Z-value: 0.87

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Transcription factors associated with rfx3_rfx2+rfx4

Gene Symbol Gene ID Gene Info
rfx3
ENSDARG00000014550 regulatory factor X, 3 (influences HLA class II expression)
rfx2
ENSDARG00000013575 regulatory factor X, 2 (influences HLA class II expression)
rfx4
ENSDARG00000026395 regulatory factor X, 4
rfx4
ENSDARG00000116861 regulatory factor X, 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rfx2dr11_v1_chr8_-_20138054_20138251-0.427.5e-02Click!
rfx4dr11_v1_chr18_-_15373620_15373620-0.331.7e-01Click!
rfx3dr11_v1_chr10_-_641609_641609-0.311.9e-01Click!

Activity profile of rfx3_rfx2+rfx4 motif

Sorted Z-values of rfx3_rfx2+rfx4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_68789 3.04 ENSDART00000058569
cldn1
claudin 1
chr20_-_9436521 1.75 ENSDART00000133000
zgc:101840
zgc:101840
chr15_+_47903864 1.56 ENSDART00000063835
otx5
orthodenticle homolog 5
chr11_-_279328 1.54 ENSDART00000066179
npffl
neuropeptide FF-amide peptide precursor like
chr3_-_1190132 1.45 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr16_+_24632096 1.38 ENSDART00000157237
si:dkey-56f14.7
si:dkey-56f14.7
chr5_-_21044693 1.36 ENSDART00000140298
si:dkey-13n15.2
si:dkey-13n15.2
chr19_-_10551394 1.16 ENSDART00000186815
ENSDART00000181041
lim2.4
lens intrinsic membrane protein 2.4
chr16_-_45069882 1.12 ENSDART00000058384
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr13_+_33117528 1.02 ENSDART00000085719
si:ch211-10a23.2
si:ch211-10a23.2
chr5_-_71705191 0.95 ENSDART00000187767
ak1
adenylate kinase 1
chr21_+_26697536 0.95 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr7_+_22675475 0.93 ENSDART00000134423
ponzr3
plac8 onzin related protein 3
chr23_-_40295610 0.91 ENSDART00000186719
CABZ01067002.1

chr21_-_15929041 0.86 ENSDART00000080693
lhx5
LIM homeobox 5
chr5_+_32162684 0.83 ENSDART00000134472
taok3b
TAO kinase 3b
chr11_-_97817 0.82 ENSDART00000092903
elmo2
engulfment and cell motility 2
chr5_-_72390259 0.82 ENSDART00000172302
wbp1
WW domain binding protein 1
chr2_+_6126638 0.81 ENSDART00000153916
fzr1b
fizzy/cell division cycle 20 related 1b
chr22_-_25033105 0.77 ENSDART00000124220
nptxrb
neuronal pentraxin receptor b
chr19_-_9472893 0.77 ENSDART00000045565
ENSDART00000137505
vamp1
vesicle-associated membrane protein 1
chr1_-_3295045 0.76 ENSDART00000157572
gpc5a
glypican 5a
chr20_-_3915770 0.75 ENSDART00000159322
si:ch73-111k22.3
si:ch73-111k22.3
chr10_-_35542071 0.75 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr10_-_29900546 0.73 ENSDART00000147441
lim2.1
lens intrinsic membrane protein 2.1
chr17_-_21784152 0.73 ENSDART00000127254
hmx2
H6 family homeobox 2
chr8_-_54304381 0.72 ENSDART00000184177
RHO (1 of many)
rhodopsin
chr24_-_1021318 0.71 ENSDART00000181403
ralaa
v-ral simian leukemia viral oncogene homolog Aa (ras related)
chr10_+_37145007 0.71 ENSDART00000131777
cuedc1a
CUE domain containing 1a
chr5_-_23317477 0.71 ENSDART00000090171
nlgn3b
neuroligin 3b
chr8_+_21195420 0.70 ENSDART00000100234
ENSDART00000091307
col2a1a
collagen, type II, alpha 1a
chr23_+_35708730 0.69 ENSDART00000009277
tuba1a
tubulin, alpha 1a
chr19_-_103289 0.69 ENSDART00000143118
adgrb1b
adhesion G protein-coupled receptor B1b
chr16_-_50175069 0.66 ENSDART00000192979
lim2.5
lens intrinsic membrane protein 2.5
chr9_-_443451 0.65 ENSDART00000165642
si:dkey-11f4.14
si:dkey-11f4.14
chr20_+_20638034 0.64 ENSDART00000189759
rtn1b
reticulon 1b
chr21_-_22828593 0.64 ENSDART00000150993
angptl5
angiopoietin-like 5
chr20_+_20637866 0.64 ENSDART00000060203
ENSDART00000079079
rtn1b
reticulon 1b
chr21_+_41743493 0.63 ENSDART00000192669
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr5_-_29643930 0.63 ENSDART00000161250
grin1b
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr1_+_37391716 0.62 ENSDART00000191986
sparcl1
SPARC-like 1
chr3_-_61181018 0.62 ENSDART00000187970
pvalb4
parvalbumin 4
chr10_+_76864 0.62 ENSDART00000036375
vps26c
Down syndrome critical region 3
chr20_-_43775495 0.61 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matn3a
matrilin 3a
chr2_-_33455164 0.60 ENSDART00000134024
ENSDART00000132221
ccdc24
coiled-coil domain containing 24
chr19_+_29337789 0.59 ENSDART00000021396
ldlrap1a
low density lipoprotein receptor adaptor protein 1a
chr10_+_9410304 0.57 ENSDART00000080843
ndufa8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
chr17_-_24684687 0.56 ENSDART00000105457
morn2
MORN repeat containing 2
chr25_-_25736958 0.54 ENSDART00000166308
cib2
calcium and integrin binding family member 2
chr9_+_2393764 0.53 ENSDART00000172624
chn1
chimerin 1
chr13_+_28821841 0.53 ENSDART00000179900
CU639469.1

chr25_+_17862338 0.53 ENSDART00000151853
ENSDART00000090867
btbd10a
BTB (POZ) domain containing 10a
chr23_+_19558574 0.51 ENSDART00000137811
atp6ap1lb
ATPase H+ transporting accessory protein 1 like b
chr13_-_31470439 0.50 ENSDART00000076574
rtn1a
reticulon 1a
chr11_-_11518469 0.50 ENSDART00000104254
krt15
keratin 15
chr16_+_221739 0.50 ENSDART00000180243
nrsn1
neurensin 1
chr1_-_56223913 0.49 ENSDART00000019573
zgc:65894
zgc:65894
chr12_-_47793857 0.48 ENSDART00000161294
dydc2
DPY30 domain containing 2
chr3_-_50277959 0.48 ENSDART00000082773
ENSDART00000139524
arl16
ADP-ribosylation factor-like 16
chr9_-_712308 0.47 ENSDART00000144625
ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr18_+_50276337 0.46 ENSDART00000140352
si:dkey-105e17.1
si:dkey-105e17.1
chr20_+_18225329 0.45 ENSDART00000144172
kctd1
potassium channel tetramerization domain containing 1
chr18_+_50275933 0.44 ENSDART00000143911
si:dkey-105e17.1
si:dkey-105e17.1
chr20_-_32270866 0.44 ENSDART00000153140
armc2
armadillo repeat containing 2
chr18_+_30028135 0.44 ENSDART00000140825
ENSDART00000145306
ENSDART00000136810
si:ch211-220f16.1
si:ch211-220f16.1
chr17_-_40397752 0.44 ENSDART00000178483
BX548062.1

chr25_+_37480285 0.43 ENSDART00000166187
CABZ01095001.1

chr14_-_52542928 0.43 ENSDART00000075749
ppp2r2ba
protein phosphatase 2, regulatory subunit B, beta a
chr18_-_41232297 0.43 ENSDART00000036928
fbxo36a
F-box protein 36a
chr20_+_591505 0.43 ENSDART00000046438
kcnk2b
potassium channel, subfamily K, member 2b
chr9_-_44289636 0.42 ENSDART00000110411
cerkl
ceramide kinase-like
chr3_-_34337969 0.42 ENSDART00000151634
tnrc6c1
trinucleotide repeat containing 6C1
chr17_-_43533095 0.42 ENSDART00000125162
si:dkey-21a6.5
si:dkey-21a6.5
chr2_-_49997055 0.42 ENSDART00000140294
si:ch211-106n13.3
si:ch211-106n13.3
chr6_+_26309968 0.41 ENSDART00000153805
dzip1l
DAZ interacting zinc finger protein 1-like
chr13_+_31603988 0.41 ENSDART00000030646
six6a
SIX homeobox 6a
chr14_+_39156 0.40 ENSDART00000082184
tmem107
transmembrane protein 107
chr13_-_36911118 0.40 ENSDART00000048739
trim9
tripartite motif containing 9
chr15_-_1534232 0.40 ENSDART00000056763
ENSDART00000133943
ift80
intraflagellar transport 80 homolog (Chlamydomonas)
chr15_+_44053244 0.39 ENSDART00000059550
lrrc51
leucine rich repeat containing 51
chr4_-_27398385 0.39 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr19_-_8604429 0.38 ENSDART00000151165
trim46b
tripartite motif containing 46b
chr24_-_2917540 0.38 ENSDART00000164776
fam69c
family with sequence similarity 69, member C
chr20_-_40766387 0.38 ENSDART00000061173
hsdl1
hydroxysteroid dehydrogenase like 1
chr6_+_49901465 0.38 ENSDART00000023515
chmp4ba
charged multivesicular body protein 4Ba
chr10_+_36037977 0.37 ENSDART00000164678
katnal1
katanin p60 subunit A-like 1
chr15_-_28907709 0.36 ENSDART00000017268
eml2
echinoderm microtubule associated protein like 2
chr4_-_390431 0.36 ENSDART00000067482
ENSDART00000138500
dynlt1
dynein, light chain, Tctex-type 1
chr6_-_8597735 0.36 ENSDART00000151294
fopnl
fgfr1op N-terminal like
chr5_+_66353750 0.35 ENSDART00000143410
si:ch211-261c8.5
si:ch211-261c8.5
chr2_-_103388 0.35 ENSDART00000169372
angptl1b
angiopoietin-like 1b
chr17_-_8753354 0.35 ENSDART00000154593
tex36
testis expressed 36
chr10_-_17179415 0.35 ENSDART00000131751
depdc5
DEP domain containing 5
chr4_-_5652030 0.35 ENSDART00000010903
rsph9
radial spoke head 9 homolog
chr1_+_54908895 0.34 ENSDART00000145652
golga7ba
golgin A7 family, member Ba
chr10_-_36682509 0.34 ENSDART00000148093
ENSDART00000063365
dnajb13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr10_-_5847904 0.34 ENSDART00000161096
ankrd55
ankyrin repeat domain 55
chr16_-_44399335 0.33 ENSDART00000165058
rims2a
regulating synaptic membrane exocytosis 2a
chr17_-_39779906 0.33 ENSDART00000155181
pimr61
Pim proto-oncogene, serine/threonine kinase, related 61
chr10_-_5847655 0.33 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr10_-_29744921 0.33 ENSDART00000088605
ift46
intraflagellar transport 46 homolog (Chlamydomonas)
chr12_+_6465557 0.32 ENSDART00000066477
ENSDART00000122271
dkk1b
dickkopf WNT signaling pathway inhibitor 1b
chr21_+_22828500 0.32 ENSDART00000151109
si:rp71-1p14.7
si:rp71-1p14.7
chr24_+_26345427 0.32 ENSDART00000089756
lrrc34
leucine rich repeat containing 34
chr4_+_9836465 0.32 ENSDART00000004879
hsp90b1
heat shock protein 90, beta (grp94), member 1
chr2_+_35728033 0.31 ENSDART00000002094
ankrd45
ankyrin repeat domain 45
chr23_-_19953089 0.31 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr25_+_22571475 0.30 ENSDART00000161559
stra6
stimulated by retinoic acid 6
chr21_-_32284532 0.30 ENSDART00000190676
clk4b
CDC-like kinase 4b
chr5_-_42661012 0.29 ENSDART00000158339
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr17_+_33767890 0.29 ENSDART00000193177
fut8a
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr16_+_27345383 0.29 ENSDART00000078250
ENSDART00000162857
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr24_-_24163201 0.29 ENSDART00000140170
map7d2b
MAP7 domain containing 2b
chr18_-_21640389 0.29 ENSDART00000100857
slc38a8a
solute carrier family 38, member 8a
chr5_-_64213253 0.29 ENSDART00000171711
gpsm1a
G protein signaling modulator 1a
chr25_+_21895182 0.29 ENSDART00000152075
si:ch211-147k9.8
si:ch211-147k9.8
chr16_+_32051572 0.29 ENSDART00000039109
leng1
leukocyte receptor cluster (LRC) member 1
chr17_-_39772999 0.29 ENSDART00000155727
pimr60
Pim proto-oncogene, serine/threonine kinase, related 60
chr2_+_47581997 0.29 ENSDART00000112579
scg2b
secretogranin II (chromogranin C), b
chr24_+_26345609 0.28 ENSDART00000186844
lrrc34
leucine rich repeat containing 34
chr15_-_28908027 0.28 ENSDART00000182790
ENSDART00000192461
eml2
echinoderm microtubule associated protein like 2
chr10_+_31222656 0.28 ENSDART00000140988
ENSDART00000143387
tmem218
transmembrane protein 218
chr2_-_21167652 0.28 ENSDART00000185792
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr10_-_40352250 0.27 ENSDART00000150821
taar20f
trace amine associated receptor 20f
chr2_+_47582488 0.27 ENSDART00000149967
scg2b
secretogranin II (chromogranin C), b
chr16_+_46492756 0.27 ENSDART00000105931
rpz5
rapunzel 5
chr19_+_28187480 0.27 ENSDART00000183825
irx4b
iroquois homeobox 4b
chr2_+_36007449 0.27 ENSDART00000161837
lamc2
laminin, gamma 2
chr23_-_33640959 0.27 ENSDART00000187599
ENSDART00000189475
csrnp2
cysteine-serine-rich nuclear protein 2
chr8_-_25338709 0.27 ENSDART00000131616
atp5pb
ATP synthase peripheral stalk-membrane subunit b
chr1_-_45633955 0.27 ENSDART00000044057
sept3
septin 3
chr24_-_24162930 0.27 ENSDART00000080602
map7d2b
MAP7 domain containing 2b
chr3_-_30123113 0.26 ENSDART00000153562
ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr3_-_52644737 0.26 ENSDART00000126180
si:dkey-210j14.3
si:dkey-210j14.3
chr4_-_8903240 0.26 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr6_-_46053300 0.26 ENSDART00000169722
ca16b
carbonic anhydrase XVI b
chr6_-_9236309 0.26 ENSDART00000160397
ENSDART00000164603
iqcb1
IQ motif containing B1
chr22_-_18491813 0.25 ENSDART00000105419
si:ch211-212d10.2
si:ch211-212d10.2
chr4_+_7822773 0.25 ENSDART00000171391
si:ch1073-67j19.2
si:ch1073-67j19.2
chr17_-_10838434 0.25 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr7_-_19364813 0.25 ENSDART00000173977
ntn4
netrin 4
chr16_+_21738194 0.25 ENSDART00000163688
FP085428.1
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr2_+_47582681 0.25 ENSDART00000187579
scg2b
secretogranin II (chromogranin C), b
chr24_-_38816725 0.24 ENSDART00000063231
nog2
noggin 2
chr20_+_20672163 0.24 ENSDART00000027758
rtn1b
reticulon 1b
chr19_+_22062202 0.24 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr3_+_46762703 0.23 ENSDART00000133283
prkcsh
protein kinase C substrate 80K-H
chr20_+_27691307 0.23 ENSDART00000153299
si:dkey-1h6.8
si:dkey-1h6.8
chr9_-_31747106 0.23 ENSDART00000048469
ENSDART00000145204
ENSDART00000186889
nalcn
sodium leak channel, non-selective
chr14_-_44841335 0.23 ENSDART00000173011
GRXCR1
si:dkey-109l4.6
chr8_+_47571211 0.23 ENSDART00000131460
plch2a
phospholipase C, eta 2a
chr2_+_19578446 0.23 ENSDART00000164758
pimr50
Pim proto-oncogene, serine/threonine kinase, related 50
chr6_+_18359306 0.23 ENSDART00000157796
cbx8b
chromobox homolog 8b
chr21_+_25068215 0.23 ENSDART00000167523
ENSDART00000189259
dixdc1b
DIX domain containing 1b
chr18_-_18874921 0.23 ENSDART00000193332
arl2bp
ADP-ribosylation factor-like 2 binding protein
chr10_-_41285235 0.23 ENSDART00000141190
brf2
BRF2, RNA polymerase III transcription initiation factor
chr24_-_32408404 0.22 ENSDART00000144157
si:ch211-56a11.2
si:ch211-56a11.2
chr5_+_23190642 0.22 ENSDART00000144846
cfap73
cilia and flagella associated protein 73
chr5_+_66353589 0.22 ENSDART00000138246
si:ch211-261c8.5
si:ch211-261c8.5
chr17_-_6759006 0.22 ENSDART00000184692
ENSDART00000180530
vsnl1b
visinin-like 1b
chr23_-_20133994 0.22 ENSDART00000004871
lrrc23
leucine rich repeat containing 23
chr9_+_2041535 0.22 ENSDART00000093187
lnpa
limb and neural patterns a
chr24_-_205275 0.22 ENSDART00000108762
vopp1
VOPP1, WBP1/VOPP1 family member
chr16_-_13623659 0.22 ENSDART00000168978
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr1_+_31657842 0.22 ENSDART00000057880
poll
polymerase (DNA directed), lambda
chr12_-_41684729 0.21 ENSDART00000184461
jakmip3
Janus kinase and microtubule interacting protein 3
chr4_-_20177868 0.21 ENSDART00000003621
sinup
siaz-interacting nuclear protein
chr21_-_2955181 0.21 ENSDART00000158991
ENSDART00000174052
znf971
zinc finger protein 971
chr6_-_35779348 0.21 ENSDART00000191159
brinp3a.1
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr21_+_22423286 0.21 ENSDART00000133190
capslb
calcyphosine-like b
chr13_-_10261383 0.21 ENSDART00000080808
six3a
SIX homeobox 3a
chr3_-_3327573 0.21 ENSDART00000136319
ENSDART00000166667
tmem184bb
transmembrane protein 184bb
chr20_-_25631256 0.21 ENSDART00000048164
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr20_+_37825804 0.21 ENSDART00000152865
tatdn3
TatD DNase domain containing 3
chr24_+_34113424 0.21 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr5_-_33022014 0.21 ENSDART00000061149
zgc:55461
zgc:55461
chr17_+_8988374 0.20 ENSDART00000109573
akap6
A kinase (PRKA) anchor protein 6
chr23_+_30859086 0.20 ENSDART00000053661
zgc:198371
zgc:198371
chr18_+_50627085 0.20 ENSDART00000161429
chrnb4
cholinergic receptor, nicotinic, beta 4 (neuronal)
chr2_-_7843451 0.20 ENSDART00000163265
si:ch211-38m6.7
si:ch211-38m6.7
chr7_+_1045637 0.20 ENSDART00000111531
epdl1
ependymin-like 1
chr17_+_53250802 0.20 ENSDART00000143819
VASH1
vasohibin 1
chr17_-_53308832 0.20 ENSDART00000171946
ENSDART00000168269
si:ch1073-416d2.4
si:ch1073-416d2.4
chr10_+_31222433 0.20 ENSDART00000185080
tmem218
transmembrane protein 218
chr21_-_5056812 0.20 ENSDART00000139713
ENSDART00000140859
zgc:77838
zgc:77838
chr16_+_23404170 0.20 ENSDART00000170061
s100w
S100 calcium binding protein W
chr7_-_52388734 0.20 ENSDART00000174186
wdr93
WD repeat domain 93
chr10_+_39304422 0.20 ENSDART00000019267
kcnj1b
potassium inwardly-rectifying channel, subfamily J, member 1b
chr25_-_37084032 0.20 ENSDART00000025494
hprt1l
hypoxanthine phosphoribosyltransferase 1, like
chr1_+_31658011 0.20 ENSDART00000192203
poll
polymerase (DNA directed), lambda
chr5_-_38506981 0.19 ENSDART00000097822
atp1b2b
ATPase Na+/K+ transporting subunit beta 2b
chr13_+_233482 0.19 ENSDART00000102511
cfap36
cilia and flagella associated protein 36
chr16_+_13683807 0.19 ENSDART00000135508
josd2
Josephin domain containing 2
chr16_-_13623928 0.19 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr19_-_48349002 0.19 ENSDART00000168468
si:ch73-359m17.8
si:ch73-359m17.8
chr3_-_23596809 0.19 ENSDART00000156897
ube2z
ubiquitin-conjugating enzyme E2Z
chr1_+_22427135 0.19 ENSDART00000147193
si:dkey-234d14.2
si:dkey-234d14.2
chr22_+_18884971 0.19 ENSDART00000186332
fstl3
follistatin-like 3 (secreted glycoprotein)
chr6_+_29288223 0.19 ENSDART00000112099
zgc:172121
zgc:172121
chr24_+_25069609 0.19 ENSDART00000115165
amer2
APC membrane recruitment protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of rfx3_rfx2+rfx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.1 0.4 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176) regulation of apoptotic cell clearance(GO:2000425)
0.1 1.0 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.5 GO:0021557 oculomotor nerve development(GO:0021557)
0.1 0.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.3 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 1.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.1 0.2 GO:0006178 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.1 0.3 GO:0061011 hepatic duct development(GO:0061011)
0.1 0.7 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.8 GO:0001881 receptor recycling(GO:0001881)
0.1 0.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.3 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.1 2.7 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.2 GO:0032475 otolith formation(GO:0032475)
0.1 0.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.3 GO:0035889 otolith tethering(GO:0035889)
0.1 0.2 GO:1905072 cardiac jelly development(GO:1905072)
0.1 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.8 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0089700 protein kinase D signaling(GO:0089700) regulation of lymphangiogenesis(GO:1901490)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0036372 opsin transport(GO:0036372)
0.0 0.4 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 1.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.2 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.0 0.1 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.1 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.8 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 0.5 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0001840 neural plate development(GO:0001840)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0001964 startle response(GO:0001964)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:1990246 uniplex complex(GO:1990246)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.2 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.1 1.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.1 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.1 1.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.6 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.7 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.7 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.2 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.2 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.0 0.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0034632 retinol transporter activity(GO:0034632)
0.0 1.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 2.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 1.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP