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PRJEB1986: zebrafish developmental stages transcriptome
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Results for rorc
Z-value: 0.93
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Transcription factors associated with rorc
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| rorc | dr11_v1_chr16_+_17913936_17913945 | -0.35 | 1.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_43314700 Show fit | 5.17 |
ENSDART00000049045
ENSDART00000133158 |
matrilin 1 |
|
| chr14_+_17376940 Show fit | 2.90 |
ENSDART00000054590
ENSDART00000010148 |
spondin 2b, extracellular matrix protein |
|
| chr15_+_19682013 Show fit | 2.62 |
ENSDART00000127368
|
si:dkey-4p15.5 |
|
| chr6_+_13742899 Show fit | 2.43 |
ENSDART00000104722
|
cyclin-dependent kinase 5, regulatory subunit 2a (p39) |
|
| chr15_+_19681718 Show fit | 1.85 |
ENSDART00000164803
|
si:dkey-4p15.5 |
|
| chr20_+_16750177 Show fit | 1.66 |
ENSDART00000185357
|
calmodulin 1b |
|
| chr15_-_37829160 Show fit | 1.64 |
ENSDART00000099425
|
chymotrypsin-like |
|
| chr5_+_2815021 Show fit | 1.63 |
ENSDART00000020472
|
4-hydroxyphenylpyruvate dioxygenase a |
|
| chr19_+_4990320 Show fit | 1.59 |
ENSDART00000147056
|
zgc:91968 |
|
| chr21_+_27189490 Show fit | 1.58 |
ENSDART00000125349
|
BCL2 associated agonist of cell death a |
Network of associatons between targets according to the STRING database.
First level regulatory network of rorc
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.8 | GO:0051216 | cartilage development(GO:0051216) |
| 0.2 | 3.1 | GO:0090382 | phagosome maturation(GO:0090382) |
| 0.1 | 2.4 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.1 | 1.9 | GO:0000737 | DNA catabolic process, endonucleolytic(GO:0000737) |
| 0.3 | 1.6 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.2 | 1.6 | GO:0042214 | carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247) |
| 0.1 | 1.4 | GO:0051877 | pigment granule aggregation in cell center(GO:0051877) |
| 0.0 | 1.3 | GO:0030641 | regulation of cellular pH(GO:0030641) |
| 0.0 | 1.2 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.3 | 1.1 | GO:0009098 | leucine biosynthetic process(GO:0009098) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.1 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.5 | 2.4 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.2 | 1.3 | GO:0033181 | plasma membrane proton-transporting V-type ATPase complex(GO:0033181) |
| 0.1 | 1.3 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.0 | 0.8 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.7 | GO:0016342 | catenin complex(GO:0016342) |
| 0.1 | 0.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) |
| 0.0 | 0.6 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.3 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 3.6 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.2 | 2.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.2 | 1.9 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 0.5 | 1.6 | GO:0003868 | 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868) |
| 0.2 | 1.6 | GO:0003834 | beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436) |
| 0.5 | 1.4 | GO:0005131 | growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186) |
| 0.0 | 1.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.3 | 1.1 | GO:0052655 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.2 | 1.0 | GO:0070004 | cysteine-type exopeptidase activity(GO:0070004) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.1 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.9 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.6 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.8 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 0.3 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.1 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.1 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |