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PRJEB1986: zebrafish developmental stages transcriptome

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Results for rreb1a+rreb1b

Z-value: 2.44

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Transcription factors associated with rreb1a+rreb1b

Gene Symbol Gene ID Gene Info
rreb1b
ENSDARG00000042652 ras responsive element binding protein 1b
rreb1a
ENSDARG00000063701 ras responsive element binding protein 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rreb1adr11_v1_chr24_-_2450597_24505970.391.0e-01Click!
rreb1bdr11_v1_chr2_+_21048661_210486610.321.9e-01Click!

Activity profile of rreb1a+rreb1b motif

Sorted Z-values of rreb1a+rreb1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_828663 11.25 ENSDART00000181776
BX537263.4

chr5_+_817016 11.25 ENSDART00000188498
BX537263.3

chr13_-_638485 6.54 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr2_-_22535 6.24 ENSDART00000157877
CABZ01092282.1

chr7_-_10606 4.26 ENSDART00000192650
ENSDART00000186761
FO704772.2

chr9_+_51882534 4.09 ENSDART00000165493
CABZ01079550.1

chr4_+_90048 3.98 ENSDART00000166440
lrp6
low density lipoprotein receptor-related protein 6
chr20_+_52595220 3.62 ENSDART00000180610
si:dkey-235d18.5
si:dkey-235d18.5
chr24_-_38110779 3.61 ENSDART00000147783
crp
c-reactive protein, pentraxin-related
chr7_-_57949117 3.52 ENSDART00000138803
ank2b
ankyrin 2b, neuronal
chr4_+_77735212 3.47 ENSDART00000160716
si:dkey-238k10.1
si:dkey-238k10.1
chr11_-_4235811 3.38 ENSDART00000121716
si:ch211-236d3.4
si:ch211-236d3.4
chr19_+_56351 3.30 ENSDART00000168334
col14a1b
collagen, type XIV, alpha 1b
chr13_-_11536951 3.13 ENSDART00000018155
adss
adenylosuccinate synthase
chr20_-_1847433 2.87 ENSDART00000164211
CABZ01065425.1

chr10_+_16756546 2.75 ENSDART00000168624
CABZ01024659.1

chr1_-_8012476 2.60 ENSDART00000177051
CR855320.3

chr20_-_25518488 2.60 ENSDART00000186993
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr12_+_13244149 2.44 ENSDART00000186984
ENSDART00000105896
atp2a1l
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr19_+_1510971 2.39 ENSDART00000157721
SLC45A4 (1 of many)
solute carrier family 45 member 4
chr8_+_554531 2.36 ENSDART00000193623
FO704758.2

chr12_+_47162761 2.35 ENSDART00000192339
ENSDART00000167726
RYR2
ryanodine receptor 2
chr7_+_39634873 2.30 ENSDART00000114774
ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr17_-_20711735 2.27 ENSDART00000150056
ank3b
ankyrin 3b
chr7_+_7630409 2.27 ENSDART00000172934
clcn3
chloride channel 3
chr2_+_7192966 2.25 ENSDART00000142735
si:ch211-13f8.1
si:ch211-13f8.1
chr15_-_47193564 2.22 ENSDART00000172453
LSAMP
limbic system-associated membrane protein
chr19_+_43256986 2.21 ENSDART00000182336
DGKD
diacylglycerol kinase delta
chr12_+_47162456 2.18 ENSDART00000186272
ENSDART00000180811
RYR2
ryanodine receptor 2
chr15_-_42736433 2.10 ENSDART00000154379
si:ch211-181d7.1
si:ch211-181d7.1
chr21_-_45613564 2.08 ENSDART00000160324
LO018363.1

chr4_-_53370 2.06 ENSDART00000180254
ENSDART00000186529
CU856344.2

chr6_+_54239625 2.04 ENSDART00000149542
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr23_+_3591690 2.00 ENSDART00000180822
si:dkey-9l20.3
si:dkey-9l20.3
chr16_+_53387085 1.93 ENSDART00000154223
ENSDART00000101404
kif13a
kinesin family member 13A
chr2_+_22694382 1.90 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr23_+_3616224 1.90 ENSDART00000190917
si:dkey-9l20.3
si:dkey-9l20.3
chr7_+_38717624 1.88 ENSDART00000132522
syt13
synaptotagmin XIII
chr13_+_51853716 1.88 ENSDART00000175341
ENSDART00000187855
LT631684.1

chr23_+_3587230 1.85 ENSDART00000055103
si:dkey-9l20.3
si:dkey-9l20.3
chr23_-_38054 1.85 ENSDART00000170393
CABZ01074076.1

chr5_-_201600 1.80 ENSDART00000158495
CABZ01088906.1

chr23_+_22873415 1.79 ENSDART00000135130
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr21_+_45510448 1.77 ENSDART00000160494
ENSDART00000167914
fnip1
folliculin interacting protein 1
chr17_+_12075805 1.76 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr20_+_18943406 1.76 ENSDART00000193590
mtmr9
myotubularin related protein 9
chr11_-_44037692 1.74 ENSDART00000186333
FP016005.2

chr22_+_1186866 1.73 ENSDART00000167710
eps8l3a
EPS8-like 3a
chr18_+_9637744 1.68 ENSDART00000190171
pclob
piccolo presynaptic cytomatrix protein b
chr6_+_58492201 1.68 ENSDART00000156375
kcnq2b
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr20_+_4392687 1.67 ENSDART00000187271
im:7142702
im:7142702
chr9_+_36946340 1.66 ENSDART00000135281
si:dkey-3d4.3
si:dkey-3d4.3
chr13_+_12801092 1.65 ENSDART00000164040
ENSDART00000134725
si:ch211-233a24.2
si:ch211-233a24.2
chr14_-_1565317 1.63 ENSDART00000169496
CABZ01064248.1

chr8_+_54081819 1.59 ENSDART00000005857
ENSDART00000161795
prickle2a
prickle homolog 2a
chr2_-_50298337 1.59 ENSDART00000155125
cntnap2b
contactin associated protein like 2b
chr19_+_2279051 1.57 ENSDART00000182103
itgb8
integrin, beta 8
chr22_+_438714 1.53 ENSDART00000136491
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr3_+_60007703 1.53 ENSDART00000157351
ENSDART00000153928
ENSDART00000155876
si:ch211-110e21.3
si:ch211-110e21.3
chr16_-_13662514 1.51 ENSDART00000146348
shisa7a
shisa family member 7a
chr21_+_28445052 1.50 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr17_+_691453 1.49 ENSDART00000159271
fancm
Fanconi anemia, complementation group M
chr4_-_1720648 1.48 ENSDART00000103484
gas2l3
growth arrest-specific 2 like 3
chr5_+_19337108 1.48 ENSDART00000089078
acacb
acetyl-CoA carboxylase beta
chr7_-_55454406 1.47 ENSDART00000108646
piezo1
piezo-type mechanosensitive ion channel component 1
chr23_-_15284757 1.40 ENSDART00000139135
sulf2b
sulfatase 2b
chr13_+_1182257 1.40 ENSDART00000033528
ENSDART00000183702
ENSDART00000147959
tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr21_+_170038 1.40 ENSDART00000157614
klhl8
kelch-like family member 8
chr10_-_74408 1.38 ENSDART00000100073
ENSDART00000141723
dyrk1aa
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a
chr22_+_413349 1.38 ENSDART00000082453
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr5_+_71802014 1.38 ENSDART00000124939
ENSDART00000097164
LHX3
LIM homeobox 3
chr15_+_46108548 1.37 ENSDART00000099023
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr25_+_12012 1.37 ENSDART00000170348
cntn1a
contactin 1a
chr22_-_18112374 1.37 ENSDART00000191154
ncanb
neurocan b
chr8_-_5847533 1.37 ENSDART00000192489
CABZ01102147.1

chr12_+_48480632 1.37 ENSDART00000158157
arhgap44
Rho GTPase activating protein 44
chr10_+_23537576 1.36 ENSDART00000130515
CR847844.1

chr20_-_54462551 1.34 ENSDART00000171769
ENSDART00000169692
evlb
Enah/Vasp-like b
chr11_+_45461419 1.32 ENSDART00000173424
sos1
son of sevenless homolog 1 (Drosophila)
chr22_+_997838 1.31 ENSDART00000149743
pparda
peroxisome proliferator-activated receptor delta a
chr23_-_4855122 1.30 ENSDART00000133701
slc6a1a
solute carrier family 6 (neurotransmitter transporter), member 1a
chr10_+_2234283 1.30 ENSDART00000136363
cntnap3
contactin associated protein like 3
chr15_-_28618502 1.27 ENSDART00000086902
slc6a4a
solute carrier family 6 (neurotransmitter transporter), member 4a
chr16_-_52821023 1.26 ENSDART00000074718
spire1b
spire-type actin nucleation factor 1b
chr11_+_38280454 1.26 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr23_-_969844 1.25 ENSDART00000127037
cdh26.2
cadherin 26, tandem duplicate 2
chr10_+_45302425 1.25 ENSDART00000159954
zmiz2
zinc finger, MIZ-type containing 2
chr18_+_22793743 1.19 ENSDART00000150106
gnao1a
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr4_+_9279515 1.19 ENSDART00000048707
srgap1b
SLIT-ROBO Rho GTPase activating protein 1b
chr2_-_51700709 1.18 ENSDART00000188601
tgm1l1
transglutaminase 1 like 1
chr21_+_6212844 1.18 ENSDART00000150301
fnbp1b
formin binding protein 1b
chr18_-_50845804 1.17 ENSDART00000158517
PDPR
si:cabz01113374.3
chr15_-_47479119 1.16 ENSDART00000164957
inppl1a
inositol polyphosphate phosphatase-like 1a
chr25_-_1124851 1.16 ENSDART00000067558
spg11
spastic paraplegia 11
chr4_-_73162005 1.15 ENSDART00000164127
si:ch73-170d6.4
si:ch73-170d6.4
chr1_+_47585700 1.13 ENSDART00000153746
ENSDART00000084457
sh3pxd2aa
SH3 and PX domains 2Aa
chr8_-_1698155 1.13 ENSDART00000186159
CABZ01065417.1

chr18_+_14342326 1.13 ENSDART00000181013
ENSDART00000138372
si:dkey-246g23.2
si:dkey-246g23.2
chr15_-_434503 1.13 ENSDART00000122286
CABZ01056629.1

chr19_+_233143 1.12 ENSDART00000175273
syngap1a
synaptic Ras GTPase activating protein 1a
chr9_-_12493628 1.12 ENSDART00000180832
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr20_-_4407228 1.12 ENSDART00000166997
CABZ01032982.1

chr18_-_50083405 1.11 ENSDART00000098668
ENSDART00000182215
ENSDART00000165423
abcc8b
ATP-binding cassette, sub-family C (CFTR/MRP), member 8b
chr5_+_23630384 1.11 ENSDART00000013745
cx39.9
connexin 39.9
chr20_-_54192130 1.11 ENSDART00000020834
CABZ01111496.1

chr8_+_54284961 1.10 ENSDART00000122692
plxnd1
plexin D1
chr21_+_3854414 1.10 ENSDART00000122699
miga2
mitoguardin 2
chr6_+_2271559 1.10 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b
chr14_-_1432875 1.09 ENSDART00000164408
ENSDART00000159774
zgc:152774
zgc:152774
chr3_-_62380146 1.09 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr21_-_45728069 1.08 ENSDART00000185101
CU302316.1

chr2_-_44183613 1.08 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr7_-_73752955 1.08 ENSDART00000171254
ENSDART00000009888
casq1b
calsequestrin 1b
chr20_-_16972351 1.08 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
si:ch73-74h11.1
chr2_-_5776030 1.07 ENSDART00000133851
nyap2b
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2b
chr4_+_20263097 1.07 ENSDART00000138820
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr3_-_1434135 1.06 ENSDART00000149622
mgp
matrix Gla protein
chr25_+_37268900 1.06 ENSDART00000156737
si:dkey-234i14.6
si:dkey-234i14.6
chr22_+_39074688 1.06 ENSDART00000153547
ip6k1
inositol hexakisphosphate kinase 1
chr2_+_48073972 1.05 ENSDART00000186442
klf6b
Kruppel-like factor 6b
chr25_-_37465064 1.05 ENSDART00000186128
zgc:158366
zgc:158366
chr16_+_41826584 1.05 ENSDART00000147523
si:dkey-199f5.6
si:dkey-199f5.6
chr12_+_33396489 1.04 ENSDART00000149960
fasn
fatty acid synthase
chr6_-_43677125 1.04 ENSDART00000150128
foxp1b
forkhead box P1b
chr6_-_60031693 1.04 ENSDART00000160275
CABZ01079262.1

chr22_-_38459316 1.03 ENSDART00000149683
ENSDART00000098461
ptk7a
protein tyrosine kinase 7a
chr10_+_213878 1.03 ENSDART00000135903
ENSDART00000138812
mpzl1l
myelin protein zero-like 1 like
chr3_-_5664123 1.03 ENSDART00000145866
si:ch211-106h11.1
si:ch211-106h11.1
chr5_-_26181863 1.02 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr5_+_21891305 1.02 ENSDART00000136788
si:ch73-92i20.1
si:ch73-92i20.1
chr1_+_176583 1.02 ENSDART00000168760
ENSDART00000160425
LAMP1
lysosomal associated membrane protein 1
chr11_+_37049347 1.00 ENSDART00000109235
bicd2
bicaudal D homolog 2 (Drosophila)
chr18_-_49078428 0.99 ENSDART00000160702
ENSDART00000174103
BX663503.3

chr23_-_478201 0.99 ENSDART00000140749
si:ch73-181d5.4
si:ch73-181d5.4
chr12_+_42436328 0.99 ENSDART00000167324
ebf3a
early B cell factor 3a
chr10_+_428269 0.99 ENSDART00000140715
zdhhc8a
zinc finger, DHHC-type containing 8a
chr9_+_4306122 0.98 ENSDART00000193722
ENSDART00000190521
kalrna
kalirin RhoGEF kinase a
chr17_+_5931530 0.98 ENSDART00000168326
ENSDART00000189790
znf513b
zinc finger protein 513b
chr11_+_37803773 0.98 ENSDART00000019047
sox13
SRY (sex determining region Y)-box 13
chr6_+_59967994 0.98 ENSDART00000050457
zgc:65895
zgc:65895
chr10_-_641609 0.98 ENSDART00000041236
rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr5_-_3839285 0.97 ENSDART00000122292
mlxipl
MLX interacting protein like
chr23_-_306796 0.97 ENSDART00000143125
anks1aa
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr8_-_1909840 0.96 ENSDART00000147408
si:dkey-178e17.3
si:dkey-178e17.3
chr16_-_35329803 0.95 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr19_-_26943936 0.95 ENSDART00000159319
zbtb12.1
zinc finger and BTB domain containing 12, tandem duplicate 1
chr16_+_22587661 0.94 ENSDART00000129612
ENSDART00000142241
she
Src homology 2 domain containing E
chr8_-_22639794 0.93 ENSDART00000188029
iqsec2a
IQ motif and Sec7 domain 2a
chr2_-_44183451 0.91 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr24_-_21470766 0.90 ENSDART00000178121
atp8a2
ATPase phospholipid transporting 8A2
chr12_+_23892972 0.90 ENSDART00000152852
svila
supervillin a
chr6_-_58901552 0.90 ENSDART00000122003
mbd6
methyl-CpG binding domain protein 6
chr14_+_26759332 0.89 ENSDART00000088484
ahnak
AHNAK nucleoprotein
chr15_-_26568278 0.89 ENSDART00000182609
wdr81
WD repeat domain 81
chr20_-_1635922 0.88 ENSDART00000181502
CR846082.1

chr10_+_1849874 0.88 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr15_-_40175894 0.88 ENSDART00000156632
si:ch211-281l24.3
si:ch211-281l24.3
chr5_+_17780475 0.87 ENSDART00000110783
ENSDART00000115227
chfr
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr3_+_1107102 0.86 ENSDART00000092690
srebf2
sterol regulatory element binding transcription factor 2
chr23_-_21758253 0.86 ENSDART00000046613
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr9_+_32428679 0.86 ENSDART00000187650
ENSDART00000190472
plcl1
phospholipase C like 1
chr25_-_37501371 0.86 ENSDART00000160498
CABZ01088346.1

chr7_+_1306723 0.85 ENSDART00000189868
si:dkeyp-74b6.2
si:dkeyp-74b6.2
chr23_-_1348933 0.85 ENSDART00000168981
CABZ01078120.1

chr7_-_54430505 0.84 ENSDART00000167905
ano1
anoctamin 1, calcium activated chloride channel
chr10_+_3875716 0.84 ENSDART00000189268
ENSDART00000180624
TTC28
tetratricopeptide repeat domain 28
chr5_-_28029558 0.83 ENSDART00000078649
abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr8_+_37489495 0.82 ENSDART00000141516
fmodb
fibromodulin b
chr16_+_10918252 0.82 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr19_-_5380770 0.81 ENSDART00000000221
krt91
keratin 91
chr7_-_5191797 0.81 ENSDART00000172955
si:ch73-223f5.1
si:ch73-223f5.1
chr18_+_40572294 0.80 ENSDART00000147003
si:ch211-132b12.2
si:ch211-132b12.2
chr2_-_41620112 0.80 ENSDART00000138822
ENSDART00000004816
zgc:110158
zgc:110158
chr18_-_50579629 0.80 ENSDART00000188252
zgc:158464
zgc:158464
chr23_-_44233408 0.79 ENSDART00000149318
ENSDART00000085528
zgc:158659
zgc:158659
chr9_-_23807032 0.79 ENSDART00000027443
esyt3
extended synaptotagmin-like protein 3
chr5_+_32009080 0.78 ENSDART00000186885
scai
suppressor of cancer cell invasion
chr23_+_2914577 0.78 ENSDART00000184897
DHX35
zgc:158828
chr4_+_9279784 0.77 ENSDART00000014897
srgap1b
SLIT-ROBO Rho GTPase activating protein 1b
chr14_-_41556533 0.76 ENSDART00000074401
itga6l
integrin, alpha 6, like
chr2_+_52847049 0.75 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr14_-_853176 0.75 ENSDART00000041988
slc34a1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr5_+_480119 0.75 ENSDART00000055681
tek
TEK tyrosine kinase, endothelial
chr9_-_52609336 0.75 ENSDART00000114805
tmem169b
transmembrane protein 169b
chr1_+_109798 0.75 ENSDART00000165402
F7 (1 of many)
zgc:163025
chr15_+_47362728 0.74 ENSDART00000180712
CABZ01099833.1

chr6_-_442163 0.74 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
grap2b
GRB2-related adaptor protein 2b
chr5_-_30080332 0.73 ENSDART00000140049
bco2a
beta-carotene oxygenase 2a
chr16_+_68069 0.73 ENSDART00000185385
ENSDART00000159652
sox4b
SRY (sex determining region Y)-box 4b
chr5_-_417495 0.72 ENSDART00000180586
ENSDART00000189408
HOOK3
hook microtubule tethering protein 3
chr11_+_23760470 0.72 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
nfasca
neurofascin homolog (chicken) a
chr2_-_59376735 0.71 ENSDART00000193624
ftr38
finTRIM family, member 38
chr2_+_33368414 0.71 ENSDART00000077462
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr3_-_38692920 0.70 ENSDART00000155042
mpp3a
membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3)
chr9_+_36314867 0.70 ENSDART00000176763
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr8_+_1715 0.69 ENSDART00000181131
tmed7
transmembrane p24 trafficking protein 7
chr13_-_20519001 0.69 ENSDART00000168955
gfra1a
gdnf family receptor alpha 1a
chr20_-_1560724 0.69 ENSDART00000179193
ENSDART00000092508
ENSDART00000133369
ptprk
protein tyrosine phosphatase, receptor type, K
chr19_+_42754882 0.69 ENSDART00000133711
clasp2
cytoplasmic linker associated protein 2
chr5_+_337215 0.69 ENSDART00000167982
rnf170
ring finger protein 170

Network of associatons between targets according to the STRING database.

First level regulatory network of rreb1a+rreb1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.6 1.8 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.5 1.5 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.4 1.5 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.4 1.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 1.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.3 1.6 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.3 1.3 GO:0051610 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.3 0.9 GO:0035973 aggrephagy(GO:0035973)
0.3 1.5 GO:0010482 ventriculo bulbo valve development(GO:0003173) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.3 1.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.3 6.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 1.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 3.1 GO:0021754 facial nucleus development(GO:0021754)
0.2 0.7 GO:0009750 response to fructose(GO:0009750)
0.2 1.8 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.2 0.9 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 1.5 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.2 2.1 GO:0010885 regulation of cholesterol storage(GO:0010885)
0.2 0.6 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.2 1.9 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2 0.6 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.2 0.6 GO:0019695 choline metabolic process(GO:0019695)
0.2 1.3 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 0.7 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 1.7 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 1.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.7 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.2 4.2 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.1 1.5 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.4 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 1.0 GO:2000095 cerebrospinal fluid circulation(GO:0090660) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.6 GO:0035739 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.9 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.2 GO:0061217 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 2.0 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 0.4 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 1.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.9 GO:0021592 fourth ventricle development(GO:0021592)
0.1 1.4 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.9 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 0.8 GO:1901998 toxin transport(GO:1901998)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.7 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 1.0 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.8 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.4 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 1.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.5 GO:0002931 response to ischemia(GO:0002931)
0.1 1.4 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 2.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.5 GO:0003139 secondary heart field specification(GO:0003139)
0.1 0.3 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 2.4 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 7.0 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 1.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 1.1 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 2.7 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.3 GO:0007343 egg activation(GO:0007343)
0.1 0.4 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 1.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.3 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.5 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 1.3 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.3 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 2.6 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.5 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 1.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.7 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 1.0 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.0 1.1 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.6 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 1.2 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.5 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.5 GO:0045471 response to ethanol(GO:0045471)
0.0 0.7 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.9 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0003210 cardiac atrium formation(GO:0003210)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.4 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.4 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.1 GO:0035994 response to muscle stretch(GO:0035994)
0.0 1.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 1.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 2.4 GO:0006821 chloride transport(GO:0006821)
0.0 0.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.6 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.4 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 2.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.0 GO:0060039 pericardium development(GO:0060039)
0.0 2.8 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.4 GO:0046785 microtubule polymerization(GO:0046785)
0.0 1.1 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.3 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0043113 receptor clustering(GO:0043113)
0.0 0.5 GO:0009880 embryonic pattern specification(GO:0009880)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0010369 chromocenter(GO:0010369)
0.2 1.7 GO:0043194 axon initial segment(GO:0043194)
0.2 3.5 GO:0030315 T-tubule(GO:0030315)
0.2 1.6 GO:0033010 paranodal junction(GO:0033010)
0.2 0.6 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 1.1 GO:0070062 extracellular exosome(GO:0070062)
0.2 0.9 GO:0043034 costamere(GO:0043034)
0.2 1.7 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 0.8 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.2 1.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 2.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 4.3 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.1 GO:0002102 podosome(GO:0002102)
0.1 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 3.0 GO:0008305 integrin complex(GO:0008305)
0.1 3.7 GO:0042641 actomyosin(GO:0042641)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.5 GO:0031941 filamentous actin(GO:0031941)
0.0 4.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.8 GO:0005903 brush border(GO:0005903)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 1.2 GO:0016342 catenin complex(GO:0016342)
0.0 2.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.1 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 1.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 1.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0030027 lamellipodium(GO:0030027)
0.0 4.1 GO:0030424 axon(GO:0030424)
0.0 1.4 GO:0005795 Golgi stack(GO:0005795)
0.0 1.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.6 GO:0048495 Roundabout binding(GO:0048495)
0.4 1.8 GO:0071253 connexin binding(GO:0071253)
0.4 1.3 GO:0015222 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.4 1.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.4 1.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 1.5 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.3 0.8 GO:0046978 TAP1 binding(GO:0046978)
0.3 4.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.2 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 1.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.2 3.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.6 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.2 3.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 1.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 2.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 2.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 2.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 2.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.7 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.5 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.7 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.8 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 3.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.8 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0050699 WW domain binding(GO:0050699)
0.1 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.2 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 1.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.7 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 1.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 4.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.6 GO:0004601 peroxidase activity(GO:0004601)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.1 3.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.4 PID CD40 PATHWAY CD40/CD40L signaling
0.1 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 1.4 PID P73PATHWAY p73 transcription factor network
0.0 0.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 1.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases