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PRJEB1986: zebrafish developmental stages transcriptome

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Results for runx2a+runx2b

Z-value: 1.16

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Transcription factors associated with runx2a+runx2b

Gene Symbol Gene ID Gene Info
runx2a
ENSDARG00000040261 RUNX family transcription factor 2a
runx2b
ENSDARG00000059233 RUNX family transcription factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
runx2adr11_v1_chr17_+_5351922_5351922-0.223.7e-01Click!
runx2bdr11_v1_chr20_-_44055095_44055123-0.155.3e-01Click!

Activity profile of runx2a+runx2b motif

Sorted Z-values of runx2a+runx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_6641223 2.95 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr10_-_25769334 2.83 ENSDART00000134176
postna
periostin, osteoblast specific factor a
chr9_-_22205682 2.67 ENSDART00000101869
crygm2d12
crystallin, gamma M2d12
chr11_+_25481046 2.63 ENSDART00000065940
opn1lw2
opsin 1 (cone pigments), long-wave-sensitive, 2
chr21_+_7582036 2.53 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr20_-_14054083 2.50 ENSDART00000009549
rhag
Rh associated glycoprotein
chr23_+_3538463 2.34 ENSDART00000172758
si:dkey-9l20.3
si:dkey-9l20.3
chr7_+_34231782 2.17 ENSDART00000173547
lctla
lactase-like a
chr7_+_25858380 1.94 ENSDART00000148780
ENSDART00000079218
mtmr1a
myotubularin related protein 1a
chr8_+_25173317 1.91 ENSDART00000142006
gpr61
G protein-coupled receptor 61
chr14_+_6159162 1.86 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr2_-_32768951 1.86 ENSDART00000004712
bfsp2
beaded filament structural protein 2, phakinin
chr25_+_20216159 1.82 ENSDART00000048642
tnnt2d
troponin T2d, cardiac
chr16_-_16152199 1.78 ENSDART00000012718
fabp11b
fatty acid binding protein 11b
chr2_+_2223837 1.73 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr15_-_23376541 1.68 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr16_+_11724230 1.52 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr18_-_12052132 1.51 ENSDART00000074361
zgc:110789
zgc:110789
chr17_+_26815021 1.42 ENSDART00000086885
asmt2
acetylserotonin O-methyltransferase 2
chr10_-_15128771 1.37 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr19_+_30633453 1.30 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr19_+_37857936 1.27 ENSDART00000189289
nxph1
neurexophilin 1
chr13_-_29424454 1.25 ENSDART00000026765
slc18a3a
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr10_+_21797276 1.24 ENSDART00000169105
pcdh1g29
protocadherin 1 gamma 29
chr25_+_7982979 1.23 ENSDART00000171904
ucmab
upper zone of growth plate and cartilage matrix associated b
chr11_+_21053488 1.23 ENSDART00000189860
zgc:113307
zgc:113307
chr1_+_15137901 1.22 ENSDART00000111475
pcdh7a
protocadherin 7a
chr1_-_26702930 1.20 ENSDART00000109297
ENSDART00000152389
foxe1
forkhead box E1
chr25_-_7925269 1.17 ENSDART00000014274
glcea
glucuronic acid epimerase a
chr3_+_54168007 1.17 ENSDART00000109894
olfm2a
olfactomedin 2a
chr19_+_32553874 1.16 ENSDART00000078197
heyl
hes-related family bHLH transcription factor with YRPW motif-like
chr13_+_27316934 1.15 ENSDART00000164533
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr2_-_22286828 1.14 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr23_+_8797143 1.13 ENSDART00000132992
sox18
SRY (sex determining region Y)-box 18
chr16_+_50741154 1.13 ENSDART00000101627
IGLON5
zgc:110372
chr6_-_39764995 1.10 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr7_+_46368520 1.09 ENSDART00000192821
znf536
zinc finger protein 536
chr25_-_7925019 1.09 ENSDART00000183309
glcea
glucuronic acid epimerase a
chr16_+_11483811 1.08 ENSDART00000169012
ENSDART00000173042
grik5
glutamate receptor, ionotropic, kainate 5
chr14_-_30967284 1.07 ENSDART00000149435
il2rgb
interleukin 2 receptor, gamma b
chr7_+_52811291 1.07 ENSDART00000192900
CT030160.1

chr1_-_55810730 1.06 ENSDART00000100551
zgc:136908
zgc:136908
chr6_+_2097690 1.04 ENSDART00000193770
tgm2b
transglutaminase 2b
chr11_-_12051805 1.01 ENSDART00000110117
ENSDART00000182744
socs7
suppressor of cytokine signaling 7
chr16_+_31853919 1.01 ENSDART00000133886
atn1
atrophin 1
chr7_-_35516251 0.99 ENSDART00000045628
irx6a
iroquois homeobox 6a
chr8_+_37489495 0.98 ENSDART00000141516
fmodb
fibromodulin b
chr5_-_39474235 0.96 ENSDART00000171557
antxr2a
anthrax toxin receptor 2a
chr5_+_23597144 0.96 ENSDART00000143929
ENSDART00000142420
ENSDART00000032909
kat5b
K(lysine) acetyltransferase 5b
chr23_-_27822920 0.95 ENSDART00000023094
acvr1ba
activin A receptor type 1Ba
chr3_-_28428198 0.95 ENSDART00000151546
rbfox1
RNA binding fox-1 homolog 1
chr6_-_43449013 0.93 ENSDART00000122423
eevs
2-epi-5-epi-valiolone synthase
chr4_-_8882572 0.93 ENSDART00000190060
mpped1
metallophosphoesterase domain containing 1
chr3_+_15271943 0.92 ENSDART00000141752
asphd1
aspartate beta-hydroxylase domain containing 1
chr2_-_985417 0.92 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr21_+_21309164 0.90 ENSDART00000132174
si:ch211-191j22.8
si:ch211-191j22.8
chr17_-_46457622 0.90 ENSDART00000130215
TMEM179 (1 of many)
transmembrane protein 179
chr7_-_38633867 0.90 ENSDART00000137424
c1qtnf4
C1q and TNF related 4
chr7_-_38658411 0.90 ENSDART00000109463
ENSDART00000017155
npsn
nephrosin
chr18_-_10995410 0.88 ENSDART00000136751
tspan33b
tetraspanin 33b
chr15_-_12545683 0.87 ENSDART00000162807
scn2b
sodium channel, voltage-gated, type II, beta
chr25_+_19954576 0.87 ENSDART00000149335
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr1_-_30689004 0.84 ENSDART00000018827
dachc
dachshund c
chr24_-_28648949 0.84 ENSDART00000180227
tecrl2a
trans-2,3-enoyl-CoA reductase-like 2a
chr23_-_36724575 0.83 ENSDART00000159560
agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr21_-_32487061 0.82 ENSDART00000114359
ENSDART00000131591
ENSDART00000131477
si:dkeyp-72g9.4
si:dkeyp-72g9.4
chr2_-_31936966 0.82 ENSDART00000169484
ENSDART00000192492
ENSDART00000027689
amph
amphiphysin
chr8_+_19356072 0.82 ENSDART00000063272
mpeg1.2
macrophage expressed 1, tandem duplicate 2
chr19_+_40350468 0.82 ENSDART00000087444
hepacam2
HEPACAM family member 2
chr6_+_48154954 0.82 ENSDART00000019706
phc2b
polyhomeotic homolog 2b (Drosophila)
chr17_+_24006792 0.81 ENSDART00000122415
si:ch211-63b16.4
si:ch211-63b16.4
chr11_+_21076872 0.81 ENSDART00000155521
prelp
proline/arginine-rich end leucine-rich repeat protein
chr1_-_58064738 0.81 ENSDART00000073778
caspb
caspase b
chr6_-_12314475 0.81 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
si:dkey-276j7.1
chr12_-_15620090 0.80 ENSDART00000038032
acbd4
acyl-CoA binding domain containing 4
chr15_+_37197494 0.80 ENSDART00000166203
aplp1
amyloid beta (A4) precursor-like protein 1
chr10_-_20453995 0.79 ENSDART00000168541
ENSDART00000164072
si:ch211-113d22.2
si:ch211-113d22.2
chr13_+_31603988 0.77 ENSDART00000030646
six6a
SIX homeobox 6a
chr11_-_27057572 0.77 ENSDART00000043091
iqsec1b
IQ motif and Sec7 domain 1b
chr5_-_68876211 0.77 ENSDART00000097254
sftpbb
surfactant protein Bb
chr13_+_10232695 0.76 ENSDART00000080805
six2a
SIX homeobox 2a
chr7_-_35515931 0.76 ENSDART00000193324
irx6a
iroquois homeobox 6a
chr14_-_17068511 0.76 ENSDART00000163766
phox2bb
paired-like homeobox 2bb
chr22_-_10459880 0.74 ENSDART00000064801
ogn
osteoglycin
chr7_-_18656069 0.73 ENSDART00000021559
coro1b
coronin, actin binding protein, 1B
chr14_-_4076480 0.72 ENSDART00000059231
enpp6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr22_+_21317597 0.72 ENSDART00000132605
shc2
SHC (Src homology 2 domain containing) transforming protein 2
chr23_-_29376859 0.71 ENSDART00000146411
sst6
somatostatin 6
chr10_-_7974155 0.71 ENSDART00000147368
ENSDART00000075524
osbp2
oxysterol binding protein 2
chr23_+_35847538 0.71 ENSDART00000143935
rarga
retinoic acid receptor gamma a
chr14_-_17068712 0.71 ENSDART00000170277
phox2bb
paired-like homeobox 2bb
chr16_+_32995882 0.71 ENSDART00000170157
prss35
protease, serine, 35
chr24_+_32472155 0.70 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr16_-_17200120 0.70 ENSDART00000147739
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr4_-_15420452 0.69 ENSDART00000016230
plxna4
plexin A4
chr3_+_14339728 0.69 ENSDART00000184127
plppr2a
phospholipid phosphatase related 2a
chr7_+_13382852 0.68 ENSDART00000166318
dagla
diacylglycerol lipase, alpha
chr22_-_33679277 0.68 ENSDART00000169948
FO904977.1

chr20_+_5564042 0.68 ENSDART00000090934
ENSDART00000127050
nrxn3b
neurexin 3b
chr3_-_36440705 0.67 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr9_-_23118350 0.67 ENSDART00000020884
lypd6
LY6/PLAUR domain containing 6
chr2_-_50298337 0.66 ENSDART00000155125
cntnap2b
contactin associated protein like 2b
chr15_-_29586747 0.66 ENSDART00000076749
samsn1a
SAM domain, SH3 domain and nuclear localisation signals 1a
chr1_-_51465730 0.65 ENSDART00000074284
spred2a
sprouty-related, EVH1 domain containing 2a
chr11_-_12051502 0.65 ENSDART00000183462
socs7
suppressor of cytokine signaling 7
chr13_+_32144370 0.64 ENSDART00000020270
osr1
odd-skipped related transciption factor 1
chr10_+_21796477 0.64 ENSDART00000176255
pcdh1g29
protocadherin 1 gamma 29
chr25_-_18249751 0.64 ENSDART00000153950
si:dkey-106n21.1
si:dkey-106n21.1
chr7_-_61845282 0.63 ENSDART00000182586
HTRA3
HtrA serine peptidase 3
chr9_-_28867562 0.63 ENSDART00000189597
ENSDART00000060321
zgc:91818
zgc:91818
chr23_-_44207349 0.63 ENSDART00000186276
zgc:158659
zgc:158659
chr10_-_8053385 0.63 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr8_-_29713595 0.62 ENSDART00000131988
ENSDART00000077637
mpeg1.1
macrophage expressed 1, tandem duplicate 1
chr13_+_27316632 0.62 ENSDART00000016121
eef1a1a
eukaryotic translation elongation factor 1 alpha 1a
chr15_-_38154616 0.62 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr16_-_16619854 0.62 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cyp21a2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr25_+_20119466 0.62 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr12_+_26467847 0.62 ENSDART00000022495
ndel1a
nudE neurodevelopment protein 1-like 1a
chr4_-_2525916 0.61 ENSDART00000134123
ENSDART00000132581
ENSDART00000019508
csrp2
cysteine and glycine-rich protein 2
chr19_+_25504645 0.61 ENSDART00000143292
col28a1a
collagen, type XXVIII, alpha 1a
chr25_-_3470910 0.61 ENSDART00000029067
ENSDART00000186737
hbp1
HMG-box transcription factor 1
chr8_-_46926204 0.60 ENSDART00000188758
ENSDART00000143321
hes2.1
hes family bHLH transcription factor 2, tandem duplicate 1
chr11_-_12051283 0.60 ENSDART00000170516
socs7
suppressor of cytokine signaling 7
chr19_+_40856807 0.60 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr6_+_9867426 0.60 ENSDART00000151749
MPP4 (1 of many)
si:ch211-222n4.6
chr10_+_15255198 0.59 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr15_-_2184638 0.59 ENSDART00000135460
shox2
short stature homeobox 2
chr20_+_18225329 0.59 ENSDART00000144172
kctd1
potassium channel tetramerization domain containing 1
chr8_-_17067364 0.59 ENSDART00000132687
rab3c
RAB3C, member RAS oncogene family
chr16_-_39900665 0.59 ENSDART00000136719
rbms3
RNA binding motif, single stranded interacting protein
chr14_-_2163454 0.59 ENSDART00000160123
ENSDART00000169653
pcdh2ab9
pcdh2ac
protocadherin 2 alpha b 9
protocadherin 2 alpha c
chr12_-_25612170 0.58 ENSDART00000077155
six2b
SIX homeobox 2b
chr5_-_52277643 0.58 ENSDART00000010757
rgmb
repulsive guidance molecule family member b
chr19_+_8144556 0.58 ENSDART00000027274
ENSDART00000147218
efna3a
ephrin-A3a
chr3_-_5664123 0.58 ENSDART00000145866
si:ch211-106h11.1
si:ch211-106h11.1
chr13_-_23095006 0.58 ENSDART00000089242
kif1bp
kif1 binding protein
chr5_+_44190974 0.58 ENSDART00000182634
ENSDART00000190626
TMEM8B
si:dkey-84j12.1
chr10_+_25355308 0.58 ENSDART00000100415
map3k7cl
map3k7 C-terminal like
chr2_-_9748039 0.58 ENSDART00000134870
si:ch1073-170o4.1
si:ch1073-170o4.1
chr10_+_15255012 0.57 ENSDART00000023766
vldlr
very low density lipoprotein receptor
chr10_-_43771447 0.57 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr19_-_10656667 0.57 ENSDART00000081379
ENSDART00000151456
ENSDART00000143271
ENSDART00000182126
olah
oleoyl-ACP hydrolase
chr2_-_51087077 0.56 ENSDART00000167987
ftr67
finTRIM family, member 67
chr1_+_41854298 0.56 ENSDART00000192672
smox
spermine oxidase
chr19_+_40856534 0.55 ENSDART00000051950
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr15_-_29573267 0.55 ENSDART00000099947
samsn1a
SAM domain, SH3 domain and nuclear localisation signals 1a
chr14_+_30491890 0.55 ENSDART00000131174
fgf20b
fibroblast growth factor 20b
chr18_+_45573251 0.54 ENSDART00000191309
kifc3
kinesin family member C3
chr1_-_16394814 0.54 ENSDART00000013024
fgf20a
fibroblast growth factor 20a
chr5_+_61467618 0.53 ENSDART00000074073
ENSDART00000182094
alkbh4
alkB homolog 4, lysine demthylase
chr13_+_25433774 0.53 ENSDART00000141255
si:dkey-51a16.9
si:dkey-51a16.9
chr4_+_2620751 0.53 ENSDART00000013924
gpr22a
G protein-coupled receptor 22a
chr22_-_5323482 0.53 ENSDART00000145785
s1pr4
sphingosine-1-phosphate receptor 4
chr1_+_46509176 0.52 ENSDART00000166028
mcf2la
mcf.2 cell line derived transforming sequence-like a
chr23_+_28582865 0.52 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr19_-_5812319 0.52 ENSDART00000114472
si:ch211-264f5.8
si:ch211-264f5.8
chr24_+_11334733 0.52 ENSDART00000147552
ENSDART00000143171
si:dkey-12l12.1
si:dkey-12l12.1
chr5_+_57658898 0.52 ENSDART00000074268
ENSDART00000124568
zgc:153929
zgc:153929
chr21_+_33503835 0.51 ENSDART00000125658
clint1b
clathrin interactor 1b
chr15_-_24869826 0.51 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr24_-_31452875 0.51 ENSDART00000187381
ENSDART00000185128
cngb3.2
cyclic nucleotide gated channel beta 3, tandem duplicate 2
chr13_-_10261383 0.51 ENSDART00000080808
six3a
SIX homeobox 3a
chr6_+_38381957 0.50 ENSDART00000087300
gabrb3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr25_-_7974494 0.50 ENSDART00000171446
hal
histidine ammonia-lyase
chr7_+_36898850 0.50 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr5_-_33039670 0.49 ENSDART00000141361
glipr2
GLI pathogenesis-related 2
chr8_-_44868020 0.49 ENSDART00000142712
cacna1fa
calcium channel, voltage-dependent, L type, alpha 1F subunit a
chr3_-_50954607 0.49 ENSDART00000163810
cdc42ep4a
CDC42 effector protein (Rho GTPase binding) 4a
chr17_-_40397752 0.48 ENSDART00000178483
BX548062.1

chr4_-_10835620 0.48 ENSDART00000150739
ppfibp1a
PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr3_+_58379450 0.48 ENSDART00000155759
sdr42e2
short chain dehydrogenase/reductase family 42E, member 2
chr11_+_14287427 0.48 ENSDART00000180903
si:ch211-262i1.3
si:ch211-262i1.3
chr18_+_45573416 0.48 ENSDART00000132184
ENSDART00000145288
kifc3
kinesin family member C3
chr1_+_23408622 0.48 ENSDART00000140706
chrna9
cholinergic receptor, nicotinic, alpha 9
chr3_+_37197686 0.47 ENSDART00000151144
fmnl1a
formin-like 1a
chr16_-_54455573 0.47 ENSDART00000075275
pklr
pyruvate kinase L/R
chr20_+_33904258 0.47 ENSDART00000170930
rxrgb
retinoid X receptor, gamma b
chr6_+_13806466 0.47 ENSDART00000043522
tmem198b
transmembrane protein 198b
chr9_-_40765868 0.46 ENSDART00000138634
abca12
ATP-binding cassette, sub-family A (ABC1), member 12
chr6_+_52804267 0.46 ENSDART00000065681
matn4
matrilin 4
chr13_+_22675802 0.46 ENSDART00000145538
ENSDART00000143312
zgc:193505
zgc:193505
chr7_+_12976173 0.46 ENSDART00000193150
ENSDART00000149518
slc25a22b
solute carrier family 25 member 22b
chr15_+_17446796 0.46 ENSDART00000157189
snx19b
sorting nexin 19b
chr5_+_65991152 0.45 ENSDART00000097756
lcn15
lipocalin 15
chr9_-_25425381 0.45 ENSDART00000129522
acvr2aa
activin A receptor type 2Aa
chr11_+_24815667 0.45 ENSDART00000141730
rabif
RAB interacting factor
chr10_-_17103651 0.45 ENSDART00000108959
RNF208
ring finger protein 208
chr20_+_20499869 0.45 ENSDART00000036124
six1b
SIX homeobox 1b
chr20_+_43083745 0.45 ENSDART00000139014
ENSDART00000153438
moxd1l
monooxygenase, DBH-like 1, like
chr20_+_32406011 0.44 ENSDART00000018640
ENSDART00000137910
snx3
sorting nexin 3
chr25_-_25434479 0.44 ENSDART00000171589
hrasa
v-Ha-ras Harvey rat sarcoma viral oncogene homolog a
chr3_+_50310684 0.44 ENSDART00000112152
gas7a
growth arrest-specific 7a
chr7_-_33248773 0.44 ENSDART00000052389
itga11a
integrin, alpha 11a
chr19_+_2546775 0.43 ENSDART00000148527
ENSDART00000097528
sp4
sp4 transcription factor
chr22_-_34937455 0.42 ENSDART00000169217
ENSDART00000188330
ENSDART00000165142
slit1b
slit homolog 1b (Drosophila)
chr24_-_18877118 0.42 ENSDART00000092783
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr21_+_15824182 0.42 ENSDART00000065779
gnrh2
gonadotropin-releasing hormone 2
chr12_+_38774860 0.42 ENSDART00000130371
kif19
kinesin family member 19
chr14_-_6727717 0.42 ENSDART00000166979
si:dkeyp-44a8.4
si:dkeyp-44a8.4
chr10_+_17088261 0.42 ENSDART00000132103
si:dkey-106l3.7
si:dkey-106l3.7

Network of associatons between targets according to the STRING database.

First level regulatory network of runx2a+runx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0015840 urea transport(GO:0015840)
0.5 1.4 GO:0030186 melatonin metabolic process(GO:0030186)
0.5 2.7 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.4 1.3 GO:0042908 xenobiotic transport(GO:0042908)
0.4 1.5 GO:0061549 sympathetic ganglion development(GO:0061549)
0.4 1.1 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.3 3.0 GO:0006833 water transport(GO:0006833)
0.3 1.9 GO:0034389 lipid particle organization(GO:0034389)
0.2 0.7 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.7 GO:0007414 axonal defasciculation(GO:0007414)
0.2 0.6 GO:0048389 intermediate mesoderm development(GO:0048389)
0.2 2.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.2 0.7 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.2 0.5 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:0042421 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 0.7 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 0.4 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 0.4 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.7 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.7 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 1.1 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.9 GO:0001709 cell fate determination(GO:0001709)
0.1 1.7 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.5 GO:0001659 temperature homeostasis(GO:0001659)
0.1 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 1.2 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.1 0.4 GO:0045056 transcytosis(GO:0045056)
0.1 0.4 GO:0048485 sympathetic nervous system development(GO:0048485)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.2 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.1 1.0 GO:0098868 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.4 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 2.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.6 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.5 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.3 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 0.3 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 0.5 GO:0046850 regulation of bone remodeling(GO:0046850)
0.1 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.5 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.5 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.3 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0055057 neuroblast division(GO:0055057)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 2.3 GO:0045214 sarcomere organization(GO:0045214)
0.0 1.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.5 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.0 0.6 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:1901998 toxin transport(GO:1901998)
0.0 1.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.2 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.0 0.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:0035094 response to nicotine(GO:0035094)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.5 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 1.1 GO:0060840 artery development(GO:0060840)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.3 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.5 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 1.5 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0090398 cellular senescence(GO:0090398)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0032689 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 1.2 GO:0006096 glycolytic process(GO:0006096)
0.0 0.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 2.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.6 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 1.2 GO:0060348 bone development(GO:0060348)
0.0 2.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 1.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 1.4 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.2 GO:0099633 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.7 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.1 GO:0098900 regulation of action potential(GO:0098900)
0.0 0.6 GO:0021761 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.5 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 3.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.9 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.0 GO:0002836 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 1.3 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 0.8 GO:0061702 inflammasome complex(GO:0061702)
0.2 1.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 0.7 GO:0043291 RAVE complex(GO:0043291)
0.2 1.5 GO:0070938 contractile ring(GO:0070938)
0.1 1.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.9 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.6 GO:0016234 inclusion body(GO:0016234)
0.1 1.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.1 0.7 GO:0033010 paranodal junction(GO:0033010)
0.1 1.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.4 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 1.0 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 1.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0034657 GID complex(GO:0034657)
0.0 0.9 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 1.0 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.3 3.0 GO:0015250 water channel activity(GO:0015250)
0.3 1.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 1.0 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 1.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 2.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 0.7 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 1.8 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.2 0.9 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.4 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.1 3.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.6 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.5 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.3 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 0.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.6 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 2.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 1.9 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.7 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 2.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.7 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.6 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.1 GO:0033745 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.4 GO:0042805 actinin binding(GO:0042805)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.2 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 1.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 1.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.9 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 1.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway