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PRJEB1986: zebrafish developmental stages transcriptome

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Results for si:dkey-149i17.7_zic1

Z-value: 1.24

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Transcription factors associated with si:dkey-149i17.7_zic1

Gene Symbol Gene ID Gene Info
ENSDARG00000094684 si_dkey-149i17.7
ENSDARG00000015567 zic family member 1 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zic1dr11_v1_chr24_-_4973765_4973765-0.331.7e-01Click!
si:dkey-149i17.7dr11_v1_chr2_+_24885987_248859870.126.2e-01Click!

Activity profile of si:dkey-149i17.7_zic1 motif

Sorted Z-values of si:dkey-149i17.7_zic1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_37285737 4.13 ENSDART00000126879
transmembrane p24 trafficking protein 6
chr20_+_35473288 4.00 ENSDART00000047195
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1
chr10_-_2526526 3.92 ENSDART00000191726
ENSDART00000192767

chr8_-_20838342 3.84 ENSDART00000141345
si:ch211-133l5.7
chr18_+_49411417 3.65 ENSDART00000028944
zmp:0000001073
chr4_-_1324141 3.59 ENSDART00000180720
pleiotrophin
chr20_-_43775495 3.49 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matrilin 3a
chr9_-_22158784 3.19 ENSDART00000167850
crystallin, gamma M2d14
chr12_+_48634927 2.90 ENSDART00000168441
zgc:165653
chr14_-_51855047 2.85 ENSDART00000088912
complexin 1
chr3_+_24482999 2.85 ENSDART00000059179
neuronal pentraxin receptor a
chr22_-_237651 2.82 ENSDART00000075210
zgc:66156
chr17_+_13664442 2.80 ENSDART00000171689
leucine rich repeat and fibronectin type III domain containing 5a
chr20_-_18731268 2.77 ENSDART00000183893
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr11_-_669270 2.69 ENSDART00000172834
peroxisome proliferator-activated receptor gamma
chr15_+_47386939 2.50 ENSDART00000128224

chr5_+_9360394 2.42 ENSDART00000124642

chr3_+_60007703 2.42 ENSDART00000157351
ENSDART00000153928
ENSDART00000155876
si:ch211-110e21.3
chr24_-_30096666 2.41 ENSDART00000183285
phospholipid phosphatase related 4b
chr24_+_42948 2.31 ENSDART00000122785
thioredoxin related transmembrane protein 3b
chr20_+_42668875 2.28 ENSDART00000048890
solute carrier family 22 (organic cation transporter), member 2
chr3_+_14317802 2.24 ENSDART00000162023
phospholipid phosphatase related 2a
chr8_+_8845932 2.21 ENSDART00000112028
si:ch211-180f4.1
chr12_+_8003872 2.12 ENSDART00000180300
ENSDART00000126661
Rho-related BTB domain containing 1
chr21_-_40557281 2.09 ENSDART00000172327
TAO kinase 1b
chr18_+_907266 2.08 ENSDART00000171729
pyruvate kinase M1/2a
chr17_+_33296852 2.07 ENSDART00000154580
DnaJ (Hsp40) homolog, subfamily C, member 27
chr23_+_216012 2.05 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
si:ch73-162j3.4
chr13_+_27314795 1.98 ENSDART00000128726
eukaryotic translation elongation factor 1 alpha 1a
chr25_+_27923846 1.96 ENSDART00000047007
solute carrier family 13 member 1
chr11_-_669558 1.91 ENSDART00000173450
peroxisome proliferator-activated receptor gamma
chr1_+_56229674 1.90 ENSDART00000127714
complement component c3a, duplicate 2
chr15_+_9072821 1.85 ENSDART00000154463
si:dkey-202g17.3
chr5_+_9405283 1.84 ENSDART00000127306
UDP glucuronosyltransferase 2 family, polypeptide A7
chr25_-_17528994 1.82 ENSDART00000061712
si:dkey-44k1.5
chr7_-_24699985 1.82 ENSDART00000052802
calbindin 2b
chr21_-_45588720 1.78 ENSDART00000186642
ENSDART00000189531

chr10_-_25699454 1.77 ENSDART00000064376
superoxide dismutase 1, soluble
chr4_-_22671469 1.76 ENSDART00000050753
CD36 molecule (thrombospondin receptor)
chr13_+_7292061 1.74 ENSDART00000179504
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr10_-_41450367 1.69 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr22_+_5106751 1.68 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr3_+_46479913 1.64 ENSDART00000149755
tyrosine kinase 2
chr12_+_2665081 1.63 ENSDART00000147532
retinol binding protein 3
chr8_-_44015210 1.63 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
RIMS binding protein 2
RIMS binding protein 2
chr12_+_4573696 1.61 ENSDART00000152534
si:dkey-94f20.4
chr13_-_11667661 1.56 ENSDART00000102411
dynactin 1b
chr22_+_18886209 1.56 ENSDART00000144402
follistatin-like 3 (secreted glycoprotein)
chr16_+_14029283 1.55 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr11_-_37411492 1.53 ENSDART00000166468
ELKS/RAB6-interacting/CAST family member 2
chr5_+_9382301 1.51 ENSDART00000124017
UDP glucuronosyltransferase 2 family, polypeptide A7
chr19_+_43297546 1.51 ENSDART00000168002
lysosomal protein transmembrane 5
chr4_-_2162688 1.51 ENSDART00000148900
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr20_+_1960092 1.47 ENSDART00000191892

chr16_-_27640995 1.45 ENSDART00000019658
NAC alpha domain containing
chr14_+_49376011 1.43 ENSDART00000020961
TNFAIP3 interacting protein 1
chr22_+_2207502 1.42 ENSDART00000169162
si:dkeyp-79b7.12
chr11_-_18799827 1.39 ENSDART00000185438
ENSDART00000189116
ENSDART00000180504
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr16_-_30931651 1.39 ENSDART00000132643
solute carrier family 45, member 4
chr6_-_33707278 1.39 ENSDART00000188103
microtubule associated serine/threonine kinase 2
chr24_+_12200260 1.39 ENSDART00000181391

chr16_+_31511739 1.37 ENSDART00000049420
N-myc downstream regulated 1b
chr19_+_46259619 1.34 ENSDART00000158032
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr5_+_9377005 1.34 ENSDART00000124924
UDP glucuronosyltransferase 2 family, polypeptide A7
chr21_+_1381276 1.34 ENSDART00000192907
transcription factor 4
chr19_+_33139164 1.33 ENSDART00000043039
family with sequence similarity 84, member B
chr6_+_16493755 1.32 ENSDART00000126318
si:ch73-193c12.2
chr18_+_3634652 1.32 ENSDART00000159913
leucine-rich repeats and calponin homology (CH) domain containing 3
chr13_+_31172833 1.30 ENSDART00000176378

chr3_+_4346854 1.30 ENSDART00000004273
si:dkey-73p2.3
chr14_-_36409960 1.30 ENSDART00000173140
ankyrin repeat and SOCS box containing 5a
chr1_-_9231952 1.30 ENSDART00000166515
si:dkeyp-57d7.4
chr23_+_42643960 1.30 ENSDART00000172733
cytochrome P450, family 2, subfamily AE, polypeptide 1
chr4_-_4795205 1.30 ENSDART00000039313
zgc:162331
chr21_+_18353703 1.28 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr20_+_172162 1.27 ENSDART00000168765

chr25_+_37435335 1.27 ENSDART00000171602
charged multivesicular body protein 1A
chr23_+_44741500 1.25 ENSDART00000166421
ATPase Na+/K+ transporting subunit beta 2a
chr9_-_53920959 1.24 ENSDART00000149618
midline 1
chr19_+_9305964 1.23 ENSDART00000136241
si:ch73-15n24.1
chr6_-_44711942 1.23 ENSDART00000055035
contactin 3b
chr14_+_36521553 1.21 ENSDART00000136233
si:dkey-237h12.3
chr23_-_42093537 1.17 ENSDART00000122074
solute carrier family 1 (glutamate transporter), member 7b
chr10_+_37182626 1.17 ENSDART00000137636
kinase suppressor of ras 1a
chr11_+_14937904 1.15 ENSDART00000185103

chr25_-_19661198 1.13 ENSDART00000149641
ATPase plasma membrane Ca2+ transporting 1b
chr4_-_52189449 1.09 ENSDART00000192426

chr11_+_45436703 1.07 ENSDART00000168295
ENSDART00000173293
son of sevenless homolog 1 (Drosophila)
chr17_-_52587598 1.06 ENSDART00000061497
si:ch211-173a9.6
chr9_-_23253870 1.05 ENSDART00000143657
ENSDART00000169911
aminocarboxymuconate semialdehyde decarboxylase
chr5_-_1047222 1.05 ENSDART00000181112
methyl-CpG binding domain protein 2
chr12_-_4651988 1.04 ENSDART00000182836
si:ch211-255p10.4
chr7_-_67842997 1.03 ENSDART00000169763
polyamine modulated factor 1 binding protein 1
chr13_-_6250317 1.02 ENSDART00000180416
tubulin, alpha 4 like
chr10_-_20481763 1.01 ENSDART00000091156
ENSDART00000192358
transforming, acidic coiled-coil containing protein 1
chr23_+_45611649 1.01 ENSDART00000169521
doublecortin-like kinase 2b
chr8_+_31777633 0.99 ENSDART00000142519
3-oxoacid CoA transferase 1a
chr10_+_7182423 0.99 ENSDART00000186788
pleckstrin and Sec7 domain containing 3, like
chr25_-_36248053 0.98 ENSDART00000134928
nuclear factor of activated T cells 3b
chr20_-_53624645 0.97 ENSDART00000083427
ENSDART00000152920
solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29
chr23_+_40139765 0.97 ENSDART00000185376
G protein signaling modulator 2, like
chr11_+_43363075 0.96 ENSDART00000179934

chr16_-_20492799 0.95 ENSDART00000014769
chimerin 2
chr1_+_23230459 0.94 ENSDART00000147857
si:dkey-92j12.5
chr17_+_5915875 0.94 ENSDART00000184179
fibronectin type III domain containing 4b
chr23_-_46217134 0.94 ENSDART00000189477
ENSDART00000168352

chr18_+_50461981 0.94 ENSDART00000158761

chr21_+_3093419 0.93 ENSDART00000162520
SHC adaptor protein 3
chr23_+_35759843 0.93 ENSDART00000047082
ganglioside induced differentiation associated protein 1-like 1
chr4_-_51460013 0.92 ENSDART00000193382

chr8_-_14126646 0.89 ENSDART00000027225
biglycan a
chr11_-_44999858 0.88 ENSDART00000167759
ENSDART00000126845
LIM-domain binding 1b
chr7_-_32599669 0.87 ENSDART00000173752
potassium voltage-gated channel, shaker-related subfamily, member 4
chr7_-_35126374 0.87 ENSDART00000141211
hydroxysteroid (11-beta) dehydrogenase 2
chr7_+_36539124 0.87 ENSDART00000173653
chromodomain helicase DNA binding protein 9
chr10_-_19497914 0.86 ENSDART00000132084
si:ch211-127i16.2
chr5_-_5326010 0.85 ENSDART00000161946
pre-B-cell leukemia homeobox 3a
chr24_-_39772045 0.85 ENSDART00000087441
si:ch211-276f18.2
chr22_+_15438513 0.85 ENSDART00000010846
glypican 5b
chr25_-_37205061 0.85 ENSDART00000155620
si:dkey-234i14.2
chr13_+_1357552 0.84 ENSDART00000114907
interferon gamma receptor 1
chr17_-_44584811 0.84 ENSDART00000165059
ENSDART00000165252
solute carrier family 35, member F4
chr11_-_1967438 0.83 ENSDART00000155844
nuclear receptor subfamily 1, group D, member 4b
chr8_-_7386978 0.82 ENSDART00000058321
LHFPL tetraspan subfamily member 4b
chr5_-_45651548 0.82 ENSDART00000097645
neuropeptide FF receptor 2a
chr2_+_5245692 0.82 ENSDART00000108990
peroxisomal biogenesis factor 5-like b
chr7_-_13884610 0.80 ENSDART00000006897
retinaldehyde binding protein 1a
chr22_+_15438872 0.80 ENSDART00000139800
glypican 5b
chr13_-_8279533 0.79 ENSDART00000109666
si:ch211-250c4.5
chr15_-_4094888 0.79 ENSDART00000166307
si:dkey-83h2.3
chr14_+_14224730 0.77 ENSDART00000180112
ENSDART00000184891
ENSDART00000174760
neuroligin 3a
chr1_+_45085194 0.77 ENSDART00000193863
si:ch211-151p13.8
chr14_+_23518110 0.76 ENSDART00000112930
si:ch211-221f10.2
chr19_+_37620342 0.74 ENSDART00000158960
thrombospondin, type I, domain containing 7Aa
chr20_-_52846212 0.74 ENSDART00000040265
TBC1 domain family, member 7
chr13_-_33198150 0.74 ENSDART00000137576
thyroid hormone receptor interactor 11
chr3_-_4253214 0.73 ENSDART00000155807
si:dkey-175d9.2
chr16_+_50755133 0.73 ENSDART00000029283
zgc:110372
chr24_-_3419998 0.73 ENSDART00000066839
solute carrier family 35, member G2b
chr16_-_13004166 0.72 ENSDART00000133735
calcium channel, voltage-dependent, gamma subunit 7b
chr18_+_5549672 0.71 ENSDART00000184970
nicotinamide nucleotide transhydrogenase 2
chr3_+_25216790 0.71 ENSDART00000156544
C1q and TNF related 6a
chr16_+_48729947 0.71 ENSDART00000049051
bromodomain containing 2b
chr3_-_61592417 0.70 ENSDART00000155082
neuronal pentraxin 2a
chr18_+_39487486 0.70 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr8_+_28667021 0.69 ENSDART00000184292
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr14_+_49395437 0.69 ENSDART00000172850
TNFAIP3 interacting protein 1
chr4_+_55494751 0.69 ENSDART00000172605

chr5_+_37487687 0.69 ENSDART00000184659

chr23_+_16620801 0.68 ENSDART00000189859
ENSDART00000184578
syntaphilin b
chr9_+_19039608 0.68 ENSDART00000055866
charged multivesicular body protein 2Ba
chr6_-_49983329 0.68 ENSDART00000113083
agouti signaling protein 1
chr22_+_35275206 0.68 ENSDART00000112234
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr7_-_23848012 0.67 ENSDART00000146104
ENSDART00000175108
si:ch211-200p22.4
chr5_-_66301142 0.67 ENSDART00000067541
prolactin receptor b
chr25_-_169291 0.66 ENSDART00000128344
lipase, hepatic b
chr7_-_36358303 0.66 ENSDART00000130028
fat mass and obesity associated
chr1_+_15204633 0.65 ENSDART00000188410
intelectin 1
chr21_-_26520629 0.65 ENSDART00000142731
Ras converting CAAX endopeptidase 1b
chr8_+_54055390 0.64 ENSDART00000102696
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr14_-_4043818 0.63 ENSDART00000179870
sorting nexin 25
chr7_-_36358735 0.63 ENSDART00000188392
fat mass and obesity associated
chr14_+_52413846 0.63 ENSDART00000160952
nitric oxide associated 1
chr6_+_10338554 0.62 ENSDART00000186936
cordon-bleu WH2 repeat protein-like 1a
chr13_-_25719628 0.62 ENSDART00000135383
si:dkey-192p21.6
chr21_+_22985078 0.61 ENSDART00000156491
lysophosphatidic acid receptor 6b
chr19_-_379750 0.61 ENSDART00000102725
tumor necrosis factor, alpha-induced protein 8-like 2a
chr4_+_8376362 0.60 ENSDART00000138653
ENSDART00000132647
ELKS/RAB6-interacting/CAST family member 1b
chr23_-_32892441 0.60 ENSDART00000147998
plexin A2
chr17_+_15882533 0.59 ENSDART00000164124
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr11_-_45141309 0.59 ENSDART00000181736
calcium activated nucleotidase 1b
chr25_+_37435720 0.59 ENSDART00000164390
charged multivesicular body protein 1A
chr8_+_7756893 0.58 ENSDART00000191894
FYVE, RhoGEF and PH domain containing 1
chr15_-_25613114 0.58 ENSDART00000182431
ENSDART00000187405
TAO kinase 1a
chr14_-_451555 0.58 ENSDART00000190906
FAT atypical cadherin 4
chr12_+_40905427 0.58 ENSDART00000170526
ENSDART00000185771
ENSDART00000193945
cadherin 18
chr3_+_14339728 0.58 ENSDART00000184127
phospholipid phosphatase related 2a
chr23_+_2361184 0.57 ENSDART00000184469

chr10_+_40836378 0.57 ENSDART00000085792
tripartite motif containing 69
chr17_-_3303805 0.55 ENSDART00000169136

chr21_+_3901775 0.55 ENSDART00000053609
dolichyldiphosphatase 1
chr6_+_42587637 0.55 ENSDART00000179964
CaM kinase-like vesicle-associated a
chr3_+_46479705 0.55 ENSDART00000181564
tyrosine kinase 2
chr10_+_35329751 0.54 ENSDART00000148043
si:dkey-259j3.5
chr25_-_21092222 0.54 ENSDART00000154765
proline rich 5a (renal)
chr3_-_2613990 0.53 ENSDART00000137102
si:dkey-217f16.6
chr4_+_5842433 0.53 ENSDART00000124085
ENSDART00000179848
ubiquitin specific peptidase 18
chr7_-_52842007 0.53 ENSDART00000182710
microtubule-associated protein 1Aa
chr14_+_14225048 0.52 ENSDART00000168749
neuroligin 3a
chr7_-_7692992 0.51 ENSDART00000192619
aminoadipate aminotransferase
chr13_-_41482064 0.51 ENSDART00000188322
ENSDART00000164732
protocadherin-related 15a
chr23_+_22267374 0.50 ENSDART00000079035
RAP1 GTPase activating protein
chr9_-_21238159 0.49 ENSDART00000146764
ENSDART00000102143
COX17 cytochrome c oxidase copper chaperone
chr12_+_31735159 0.49 ENSDART00000185442
si:dkey-49c17.3
chr12_-_1034383 0.49 ENSDART00000152455
ENSDART00000152346
polymerase (RNA) III (DNA directed) polypeptide E
chr22_-_3449282 0.48 ENSDART00000136798
protein tyrosine phosphatase, receptor type, s, a
chr23_-_19434199 0.48 ENSDART00000132543
kelch domain containing 8B
chr8_-_34762163 0.48 ENSDART00000114080
SET domain containing 1B, b
chr6_+_518979 0.48 ENSDART00000151012
si:ch73-379f7.5
chr17_+_20173882 0.47 ENSDART00000155379
si:ch211-248a14.8

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-149i17.7_zic1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0015695 organic cation transport(GO:0015695)
0.6 2.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.5 1.8 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.4 1.3 GO:0042245 RNA repair(GO:0042245)
0.3 4.6 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.3 1.4 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.2 1.0 GO:0006844 acyl carnitine transport(GO:0006844)
0.2 5.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 0.7 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.2 0.7 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.2 0.6 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 0.6 GO:0003403 optic vesicle formation(GO:0003403)
0.2 1.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 1.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 1.4 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 0.7 GO:0006740 NADPH regeneration(GO:0006740)
0.2 1.8 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 1.1 GO:0019805 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.2 0.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 1.7 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 1.9 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 1.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.7 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.7 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.4 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.9 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 1.3 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.1 1.3 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.3 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 1.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.9 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 0.2 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.1 0.8 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 2.0 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 2.0 GO:0008272 sulfate transport(GO:0008272)
0.1 0.2 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 1.3 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 1.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 5.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 2.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 1.6 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.2 GO:0097435 fibril organization(GO:0097435)
0.1 0.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 3.3 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 0.3 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.2 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 4.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.7 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 1.9 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0099633 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 2.1 GO:0006096 glycolytic process(GO:0006096)
0.0 0.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.8 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 3.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.0 0.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.3 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.7 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.0 0.7 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.5 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 2.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 1.5 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 1.1 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.9 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0007602 phototransduction(GO:0007602) detection of light stimulus(GO:0009583)
0.0 1.0 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 2.1 GO:0007601 visual perception(GO:0007601)
0.0 0.4 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.8 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.4 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 1.1 GO:0006865 amino acid transport(GO:0006865)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 1.0 GO:0097224 sperm connecting piece(GO:0097224)
0.2 2.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 1.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.1 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 1.8 GO:0043195 terminal bouton(GO:0043195)
0.1 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 4.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.6 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 1.8 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.1 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.4 1.8 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.3 2.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 2.3 GO:0016972 thiol oxidase activity(GO:0016972)
0.3 1.3 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.3 3.3 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 0.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 1.8 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 0.8 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 5.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 1.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 1.6 GO:0019841 retinol binding(GO:0019841)
0.2 0.7 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.2 0.9 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.2 0.7 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 1.7 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.8 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.5 GO:0016531 copper chaperone activity(GO:0016531)
0.1 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0031779 melanocortin receptor binding(GO:0031779)
0.1 0.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 2.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 4.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.6 GO:0048185 activin binding(GO:0048185)
0.1 0.5 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 1.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.2 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.0 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 2.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.9 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 1.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 3.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 4.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 2.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0008887 glycerate kinase activity(GO:0008887)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.9 GO:0003678 DNA helicase activity(GO:0003678)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 3.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 4.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 0.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 2.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.3 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 2.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 3.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 4.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism