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PRJEB1986: zebrafish developmental stages transcriptome
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Results for si:dkey-18a10.3
Z-value: 0.47
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Transcription factors associated with si:dkey-18a10.3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| si:dkey-18a10.3 | dr11_v1_chr10_-_33572441_33572441 | 0.52 | 2.4e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_-_22318511 Show fit | 2.87 |
ENSDART00000129295
|
crystallin, gamma M2d2 |
|
| chr25_-_18470695 Show fit | 2.19 |
ENSDART00000034377
|
carboxypeptidase A5 |
|
| chr15_+_6109861 Show fit | 2.11 |
ENSDART00000185154
|
Purkinje cell protein 4 |
|
| chr9_-_22299412 Show fit | 1.78 |
ENSDART00000139101
|
crystallin, gamma M2d21 |
|
| chr9_-_11560427 Show fit | 1.71 |
ENSDART00000127942
ENSDART00000061442 |
crystallin, beta A2b |
|
| chr15_-_37850969 Show fit | 1.58 |
ENSDART00000031418
|
heat shock cognate 70 |
|
| chr6_+_9175886 Show fit | 1.28 |
ENSDART00000165333
|
si:ch211-207l14.1 |
|
| chr24_+_7495945 Show fit | 1.22 |
ENSDART00000133525
ENSDART00000182460 ENSDART00000162954 |
lysine (K)-specific methyltransferase 2Ca |
|
| chr19_-_3193912 Show fit | 1.17 |
ENSDART00000133159
|
si:ch211-133n4.6 |
|
| chr14_-_36345175 Show fit | 1.07 |
ENSDART00000077823
|
info leucine-rich repeat, immunoglobulin-like and transmembrane domains 3a |
Network of associatons between targets according to the STRING database.
First level regulatory network of si:dkey-18a10.3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.7 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.2 | 1.7 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
| 0.1 | 0.9 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.1 | 0.8 | GO:0043092 | amino acid import(GO:0043090) L-amino acid import(GO:0043092) |
| 0.1 | 0.8 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 0.8 | GO:0006707 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.2 | 0.7 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 0.1 | 0.7 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.0 | 0.7 | GO:0009437 | carnitine metabolic process(GO:0009437) |
| 0.0 | 0.7 | GO:0014823 | response to activity(GO:0014823) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 1.2 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 1.1 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 1.0 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 0.8 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.0 | 0.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.5 | GO:0035267 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.0 | 0.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.0 | 0.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 2.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 1.4 | GO:0005416 | cation:amino acid symporter activity(GO:0005416) |
| 0.1 | 1.2 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 1.0 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.1 | 1.0 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.0 | 1.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.9 | GO:0048185 | activin binding(GO:0048185) |
| 0.1 | 0.8 | GO:0033781 | cholesterol 24-hydroxylase activity(GO:0033781) |
| 0.1 | 0.7 | GO:0016416 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.2 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.7 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.6 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.0 | 0.6 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 0.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.4 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.3 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.2 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.0 | 0.2 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |