ISMARA results: si:dkey-43p13.5+uncx

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PRJEB1986: zebrafish developmental stages transcriptome

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Results for si:dkey-43p13.5+uncx

Z-value: 1.19

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Transcription factors associated with si:dkey-43p13.5+uncx

Gene Symbol	Gene ID	Gene Info
uncx NCBI UniProt	ENSDARG00000102976	UNC homeobox
si_dkey-43p13.5 NCBI UniProt	ENSDARG00000104199	si_dkey-43p13.5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
si:dkey-43p13.5	dr11_v1_chr3_+_43086548_43086548	0.77	1.0e-04	Click!
uncx	dr11_v1_chr3_-_43356082_43356082	0.18	4.7e-01	Click!

Activity profile of si:dkey-43p13.5+uncx motif

Sorted Z-values of si:dkey-43p13.5+uncx motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_55248496 Show fit	4.10	ENSDART00000098615	nanos3 NCBI UniProt Show fit	nanos homolog 3
chr25_+_14507567 Show fit	4.03	ENSDART00000015681	dbx1b NCBI UniProt Show fit	developing brain homeobox 1b
chr16_+_29509133 Show fit	3.95	ENSDART00000112116	ctss2.1 NCBI UniProt Show fit	cathepsin S, ortholog2, tandem duplicate 1
chr19_+_15440841 Show fit	3.47	ENSDART00000182329	lin28a NCBI UniProt Show fit	lin-28 homolog A (C. elegans)
chr11_-_35171768 Show fit	3.24	ENSDART00000192896	traip NCBI UniProt Show fit	TRAF-interacting protein
chr24_+_38301080 Show fit	3.22	ENSDART00000105672	mybpc2b NCBI UniProt Show fit	myosin binding protein C, fast type b
chr16_+_54209504 Show fit	3.07	ENSDART00000020033	xrcc1 NCBI UniProt Show fit	X-ray repair complementing defective repair in Chinese hamster cells 1
chr17_-_16422654 Show fit	3.05	ENSDART00000150149	tdp1 NCBI UniProt Show fit	tyrosyl-DNA phosphodiesterase 1
chr19_+_15441022 Show fit	2.99	ENSDART00000098970 ENSDART00000140276	lin28a NCBI UniProt Show fit	lin-28 homolog A (C. elegans)
chr8_+_30452945 Show fit	2.91	ENSDART00000062303	foxd5 NCBI UniProt Show fit	forkhead box D5
chr18_+_619619 Show fit	2.79	ENSDART00000159846	prtga NCBI UniProt Show fit	protogenin homolog a (Gallus gallus)
chr2_-_7246848 Show fit	2.71	ENSDART00000146434	zgc:153115 NCBI UniProt Show fit	zgc:153115
chr8_+_21353878 Show fit	2.57	ENSDART00000056420	alas2 NCBI UniProt Show fit	aminolevulinate, delta-, synthase 2
chr24_-_21923930 Show fit	2.49	ENSDART00000131944	tagln3b NCBI UniProt Show fit	transgelin 3b
chr6_+_41191482 Show fit	2.38	ENSDART00000000877	opn1mw3 NCBI UniProt Show fit	opsin 1 (cone pigments), medium-wave-sensitive, 3
chr18_-_33979693 Show fit	2.33	ENSDART00000021215	si:ch211-203b20.7 NCBI UniProt Show fit	si:ch211-203b20.7
chr3_-_60175470 Show fit	2.32	ENSDART00000156597	si:ch73-364h19.1 NCBI UniProt Show fit	si:ch73-364h19.1
chr23_-_18913032 Show fit	2.28	ENSDART00000136678	si:ch211-209j10.6 NCBI UniProt Show fit	si:ch211-209j10.6
chr12_-_35830625 Show fit	2.25	ENSDART00000180028	CU459056.1 NCBI UniProt Show fit
chr2_+_33326522 Show fit	2.24	ENSDART00000056655	klf17 NCBI UniProt Show fit	Kruppel-like factor 17
chr21_-_37194365 Show fit	2.23	ENSDART00000100286	fgfr4 NCBI UniProt Show fit	fibroblast growth factor receptor 4
chr11_-_35171162 Show fit	2.22	ENSDART00000017393	traip NCBI UniProt Show fit	TRAF-interacting protein
chr19_+_12406583 Show fit	2.20	ENSDART00000013865 ENSDART00000151535	seh1l NCBI UniProt Show fit	SEH1-like (S. cerevisiae)
chr23_-_31913069 Show fit	2.13	ENSDART00000135526	mtfr2 NCBI UniProt Show fit	mitochondrial fission regulator 2
chr12_-_43664682 Show fit	2.12	ENSDART00000159423	foxi1 NCBI UniProt Show fit	forkhead box i1
chr4_-_52165969 Show fit	2.10	ENSDART00000171130	si:dkeyp-44b5.4 NCBI UniProt Show fit	si:dkeyp-44b5.4
chr3_-_23643751 Show fit	2.10	ENSDART00000078425 ENSDART00000140264	eve1 NCBI UniProt Show fit	even-skipped-like1
chr17_-_14876758 Show fit	2.08	ENSDART00000155857	nid2a NCBI UniProt Show fit	nidogen 2a (osteonidogen)
chr18_+_19456648 Show fit	2.05	ENSDART00000079695	zwilch NCBI UniProt Show fit	zwilch kinetochore protein
chr2_+_20793982 Show fit	2.04	ENSDART00000014785	prg4a NCBI UniProt Show fit	proteoglycan 4a
chr21_+_15592426 Show fit	2.03	ENSDART00000138207	smarcb1b NCBI UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr23_-_31913231 Show fit	2.03	ENSDART00000146852 ENSDART00000085054	mtfr2 NCBI UniProt Show fit	mitochondrial fission regulator 2
chr13_+_7442023 Show fit	2.01	ENSDART00000080975	tnfaip2b NCBI UniProt Show fit	tumor necrosis factor, alpha-induced protein 2b
chr13_+_30903816 Show fit	1.99	ENSDART00000191727	ercc6 NCBI UniProt Show fit	excision repair cross-complementation group 6
chr1_-_999556 Show fit	1.96	ENSDART00000170884 ENSDART00000172235	gart NCBI UniProt Show fit	phosphoribosylglycinamide formyltransferase
chr8_+_23356264 Show fit	1.94	ENSDART00000145062	dnmt3ba NCBI UniProt Show fit	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr22_-_15593824 Show fit	1.93	ENSDART00000123125	tpm4a NCBI UniProt Show fit	tropomyosin 4a
chr8_-_50888806 Show fit	1.92	ENSDART00000053750	acsl2 NCBI UniProt Show fit	acyl-CoA synthetase long chain family member 2
chr1_-_45215343 Show fit	1.92	ENSDART00000014727	ddx39aa NCBI UniProt Show fit	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr23_-_17003533 Show fit	1.92	ENSDART00000080545	dnmt3bb.2 NCBI UniProt Show fit	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr3_-_4663602 Show fit	1.88	ENSDART00000083532	slc25a38a NCBI UniProt Show fit	solute carrier family 25, member 38a
chr2_+_58841181 Show fit	1.86	ENSDART00000164102	cirbpa NCBI UniProt Show fit	cold inducible RNA binding protein a
chr25_-_21031007 Show fit	1.86	ENSDART00000138985	gnaia NCBI UniProt Show fit	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr3_+_18807006 Show fit	1.86	ENSDART00000180091	tnpo2 NCBI UniProt Show fit	transportin 2 (importin 3, karyopherin beta 2b)
chr13_-_31296358 Show fit	1.84	ENSDART00000030946	prdm8 NCBI UniProt Show fit	PR domain containing 8
chr2_-_26596794 Show fit	1.81	ENSDART00000134685 ENSDART00000056787	zgc:113691 NCBI UniProt Show fit	zgc:113691
chr3_-_30488063 Show fit	1.80	ENSDART00000055393 ENSDART00000151367	med25 NCBI UniProt Show fit	mediator complex subunit 25
chr14_+_22113331 Show fit	1.80	ENSDART00000109759	tmx2a NCBI UniProt Show fit	thioredoxin-related transmembrane protein 2a
chr8_+_8936912 Show fit	1.79	ENSDART00000135958	si:dkey-83k24.5 NCBI UniProt Show fit	si:dkey-83k24.5
chr1_+_21725821 Show fit	1.78	ENSDART00000132602	pax5 NCBI UniProt Show fit	paired box 5
chr1_-_33645967 Show fit	1.77	ENSDART00000192758	cldng NCBI UniProt Show fit	claudin g
chr2_-_17115256 Show fit	1.77	ENSDART00000190488	pif1 NCBI UniProt Show fit	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr17_+_30369396 Show fit	1.75	ENSDART00000076611	greb1 NCBI UniProt Show fit	growth regulation by estrogen in breast cancer 1
chr1_+_24557414 Show fit	1.75	ENSDART00000076519	dctpp1 NCBI UniProt Show fit	dCTP pyrophosphatase 1
chr3_-_16719244 Show fit	1.74	ENSDART00000055859	pold1 NCBI UniProt Show fit	polymerase (DNA directed), delta 1, catalytic subunit
chr16_-_7443388 Show fit	1.74	ENSDART00000017445	prdm1a NCBI UniProt Show fit	PR domain containing 1a, with ZNF domain
chr7_+_56676838 Show fit	1.72	ENSDART00000112242	zgc:194679 NCBI UniProt Show fit	zgc:194679
chr8_+_17168114 Show fit	1.72	ENSDART00000183901	cenph NCBI UniProt Show fit	centromere protein H
chr22_+_18315490 Show fit	1.70	ENSDART00000160413	gatad2ab NCBI UniProt Show fit	GATA zinc finger domain containing 2Ab
chr9_+_8396755 Show fit	1.69	ENSDART00000043067	zgc:171776 NCBI UniProt Show fit	zgc:171776
chr23_-_16485190 Show fit	1.69	ENSDART00000155038	si:dkeyp-100a5.4 NCBI UniProt Show fit	si:dkeyp-100a5.4
chr15_-_14884332 Show fit	1.69	ENSDART00000165237	si:ch211-24o8.4 NCBI UniProt Show fit	si:ch211-24o8.4
chr21_-_23331619 Show fit	1.68	ENSDART00000007806	zbtb16a NCBI UniProt Show fit	zinc finger and BTB domain containing 16a
chr23_-_33775145 Show fit	1.68	ENSDART00000132147 ENSDART00000027959 ENSDART00000160116	racgap1 NCBI UniProt Show fit	Rac GTPase activating protein 1
chr23_+_31913292 Show fit	1.67	ENSDART00000136910	armc1l NCBI UniProt Show fit	armadillo repeat containing 1, like
chr10_+_16036246 Show fit	1.65	ENSDART00000141586 ENSDART00000135868 ENSDART00000065037 ENSDART00000124502	lmnb1 NCBI UniProt Show fit	lamin B1
chr24_+_19415124 Show fit	1.64	ENSDART00000186931	sulf1 NCBI UniProt Show fit	sulfatase 1
chr10_-_35257458 Show fit	1.63	ENSDART00000143890 ENSDART00000139107 ENSDART00000082445	prr11 NCBI UniProt Show fit	proline rich 11
chr15_+_1534644 Show fit	1.63	ENSDART00000130413	smc4 NCBI UniProt Show fit	structural maintenance of chromosomes 4
chr15_+_36309070 Show fit	1.61	ENSDART00000157034	gmnc NCBI UniProt Show fit	geminin coiled-coil domain containing
chr15_+_23799461 Show fit	1.61	ENSDART00000154885	si:ch211-167j9.4 NCBI UniProt Show fit	si:ch211-167j9.4
chr10_-_21362320 Show fit	1.60	ENSDART00000189789	avd NCBI UniProt Show fit	avidin
chr8_+_23355484 Show fit	1.60	ENSDART00000085361 ENSDART00000125729	dnmt3ba NCBI UniProt Show fit	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr5_+_66433287 Show fit	1.60	ENSDART00000170757	kntc1 NCBI UniProt Show fit	kinetochore associated 1
chr5_-_20205075 Show fit	1.59	ENSDART00000051611	dao.3 NCBI UniProt Show fit	D-amino-acid oxidase, tandem duplicate 3
chr17_-_48944465 Show fit	1.59	ENSDART00000154110	si:ch1073-80i24.3 NCBI UniProt Show fit	si:ch1073-80i24.3
chr5_-_12219572 Show fit	1.59	ENSDART00000167834	nos1 NCBI UniProt Show fit	nitric oxide synthase 1 (neuronal)
chr20_-_22476255 Show fit	1.59	ENSDART00000103510	pdgfra NCBI UniProt Show fit	platelet-derived growth factor receptor, alpha polypeptide
chr17_+_16046132 Show fit	1.59	ENSDART00000155005	si:ch73-204p21.2 NCBI UniProt Show fit	si:ch73-204p21.2
chr11_+_33818179 Show fit	1.59	ENSDART00000109418	spoplb NCBI UniProt Show fit	speckle-type POZ protein-like b
chr20_-_27225876 Show fit	1.58	ENSDART00000149204 ENSDART00000149732	si:dkey-85n7.7 NCBI UniProt Show fit	si:dkey-85n7.7
chr21_+_43404945 Show fit	1.58	ENSDART00000142234	frmd7 NCBI UniProt Show fit	FERM domain containing 7
chr11_-_36341028 Show fit	1.57	ENSDART00000146093	sort1a NCBI UniProt Show fit	sortilin 1a
chr3_+_45364849 Show fit	1.57	ENSDART00000153974	ube2ia NCBI UniProt Show fit	ubiquitin-conjugating enzyme E2Ia
chr1_+_513986 Show fit	1.57	ENSDART00000109083 ENSDART00000081945	txnl4b NCBI UniProt Show fit	thioredoxin-like 4B
chr19_-_5669122 Show fit	1.56	ENSDART00000112211	si:ch211-264f5.2 NCBI UniProt Show fit	si:ch211-264f5.2
chr3_+_28860283 Show fit	1.56	ENSDART00000077235	alg1 NCBI UniProt Show fit	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr13_+_22295905 Show fit	1.54	ENSDART00000180133 ENSDART00000181125	usp54a NCBI UniProt Show fit	ubiquitin specific peptidase 54a
chr22_-_36530902 Show fit	1.54	ENSDART00000056188	polr2h NCBI UniProt Show fit	info polymerase (RNA) II (DNA directed) polypeptide H
chr17_+_16046314 Show fit	1.54	ENSDART00000154554 ENSDART00000154338 ENSDART00000155336	si:ch73-204p21.2 NCBI UniProt Show fit	si:ch73-204p21.2
chr1_-_17693273 Show fit	1.53	ENSDART00000146258	cfap97 NCBI UniProt Show fit	cilia and flagella associated protein 97
chr10_-_21362071 Show fit	1.53	ENSDART00000125167	avd NCBI UniProt Show fit	avidin
chr24_+_22485710 Show fit	1.51	ENSDART00000146058	si:dkey-40h20.1 NCBI UniProt Show fit	si:dkey-40h20.1
chr1_+_43686251 Show fit	1.50	ENSDART00000074604 ENSDART00000137791	cisd2 NCBI UniProt Show fit	CDGSH iron sulfur domain 2
chr20_-_20930926 Show fit	1.50	ENSDART00000123909	btbd6b NCBI UniProt Show fit	BTB (POZ) domain containing 6b
chr4_+_11723852 Show fit	1.49	ENSDART00000028820	mkln1 NCBI UniProt Show fit	muskelin 1, intracellular mediator containing kelch motifs
chr6_-_40778294 Show fit	1.49	ENSDART00000019845	arpc4 NCBI UniProt Show fit	actin related protein 2/3 complex, subunit 4
chr12_-_5728755 Show fit	1.49	ENSDART00000105887	dlx4b NCBI UniProt Show fit	distal-less homeobox 4b
chr23_+_44374041 Show fit	1.49	ENSDART00000136056	ephb4b NCBI UniProt Show fit	eph receptor B4b
chr14_-_33945692 Show fit	1.48	ENSDART00000168546 ENSDART00000189778	zdhhc24 NCBI UniProt Show fit	zinc finger, DHHC-type containing 24
chr22_+_16535575 Show fit	1.48	ENSDART00000083063	tal1 NCBI UniProt Show fit	T-cell acute lymphocytic leukemia 1
chr14_-_38826739 Show fit	1.48	ENSDART00000187633	spdl1 NCBI UniProt Show fit	spindle apparatus coiled-coil protein 1
chr19_+_30884706 Show fit	1.48	ENSDART00000052126	yars NCBI UniProt Show fit	tyrosyl-tRNA synthetase
chr18_+_30998472 Show fit	1.47	ENSDART00000154993 ENSDART00000099333	cd151l NCBI UniProt Show fit	CD151 antigen, like
chr14_+_31496543 Show fit	1.46	ENSDART00000170683	phf6 NCBI UniProt Show fit	PHD finger protein 6
chr16_+_14812585 Show fit	1.44	ENSDART00000134087	col14a1a NCBI UniProt Show fit	collagen, type XIV, alpha 1a
chr13_+_27232848 Show fit	1.44	ENSDART00000138043	rin2 NCBI UniProt Show fit	Ras and Rab interactor 2
chr19_-_5699703 Show fit	1.43	ENSDART00000082050	zgc:174904 NCBI UniProt Show fit	zgc:174904
chr13_-_31008275 Show fit	1.42	ENSDART00000139394	wdfy4 NCBI UniProt Show fit	WDFY family member 4
chr12_+_16087077 Show fit	1.42	ENSDART00000141898	znf281b NCBI UniProt Show fit	zinc finger protein 281b
chr19_+_29808471 Show fit	1.41	ENSDART00000186428	hdac1 NCBI UniProt Show fit	histone deacetylase 1
chr16_+_42471455 Show fit	1.41	ENSDART00000166640	si:ch211-215k15.5 NCBI UniProt Show fit	si:ch211-215k15.5
chr14_-_22015232 Show fit	1.40	ENSDART00000137795	ssrp1a NCBI UniProt Show fit	structure specific recognition protein 1a
chr7_+_24023653 Show fit	1.40	ENSDART00000141165	tinf2 NCBI UniProt Show fit	TERF1 (TRF1)-interacting nuclear factor 2
chr8_+_28358161 Show fit	1.40	ENSDART00000062682	adipor1b NCBI UniProt Show fit	adiponectin receptor 1b
chr5_+_26847190 Show fit	1.39	ENSDART00000076742	imp4 NCBI UniProt Show fit	IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr23_+_11285662 Show fit	1.38	ENSDART00000111028	chl1a NCBI UniProt Show fit	cell adhesion molecule L1-like a
chr2_+_15048410 Show fit	1.38	ENSDART00000058484	cnn3b NCBI UniProt Show fit	calponin 3, acidic b
chr4_+_28356606 Show fit	1.37	ENSDART00000192995	si:ch73-263o4.4 NCBI UniProt Show fit	si:ch73-263o4.4
chr9_-_32753535 Show fit	1.37	ENSDART00000060006	olig2 NCBI UniProt Show fit	oligodendrocyte lineage transcription factor 2
chr11_-_41220794 Show fit	1.36	ENSDART00000192895	mrps16 NCBI UniProt Show fit	mitochondrial ribosomal protein S16
chr20_-_2584101 Show fit	1.36	ENSDART00000141595 ENSDART00000135760	med23 NCBI UniProt Show fit	mediator complex subunit 23
chr24_-_2450597 Show fit	1.36	ENSDART00000188080 ENSDART00000093331	rreb1a NCBI UniProt Show fit	ras responsive element binding protein 1a
chr12_-_26415499 Show fit	1.34	ENSDART00000185779	synpo2lb NCBI UniProt Show fit	synaptopodin 2-like b
chr17_-_49412313 Show fit	1.34	ENSDART00000152100	mthfd1b NCBI UniProt Show fit	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr20_+_4221978 Show fit	1.34	ENSDART00000171898	ipcef1 NCBI UniProt Show fit	interaction protein for cytohesin exchange factors 1
chr7_+_56098590 Show fit	1.33	ENSDART00000098453	cdh15 NCBI UniProt Show fit	cadherin 15, type 1, M-cadherin (myotubule)
chr13_+_35637048 Show fit	1.33	ENSDART00000085037	thbs2a NCBI UniProt Show fit	thrombospondin 2a
chr24_+_39638555 Show fit	1.31	ENSDART00000078313	luc7l NCBI UniProt Show fit	LUC7-like (S. cerevisiae)
chr17_-_31695217 Show fit	1.31	ENSDART00000104332 ENSDART00000143090	lin52 NCBI UniProt Show fit	lin-52 DREAM MuvB core complex component
chr15_+_34988148 Show fit	1.31	ENSDART00000076269	ccdc105 NCBI UniProt Show fit	coiled-coil domain containing 105
chr9_+_9927516 Show fit	1.30	ENSDART00000161089 ENSDART00000168559	ttf2 NCBI UniProt Show fit	transcription termination factor, RNA polymerase II
chr18_-_30499489 Show fit	1.30	ENSDART00000033746	gins2 NCBI UniProt Show fit	GINS complex subunit 2
chr2_+_9970942 Show fit	1.29	ENSDART00000153063	sec22ba NCBI UniProt Show fit	SEC22 homolog B, vesicle trafficking protein a
chr3_-_12930217 Show fit	1.29	ENSDART00000166322	pdgfab NCBI UniProt Show fit	platelet-derived growth factor alpha polypeptide b
chr8_+_16758304 Show fit	1.29	ENSDART00000133514	elovl7a NCBI UniProt Show fit	ELOVL fatty acid elongase 7a
chr20_+_25586099 Show fit	1.29	ENSDART00000063122 ENSDART00000134047	cyp2p10 NCBI UniProt Show fit	cytochrome P450, family 2, subfamily P, polypeptide 10
chr21_+_723998 Show fit	1.29	ENSDART00000160956	oaz1b NCBI UniProt Show fit	ornithine decarboxylase antizyme 1b
chr7_+_72003301 Show fit	1.29	ENSDART00000012918 ENSDART00000182268 ENSDART00000185750	psmd9 NCBI UniProt Show fit	proteasome 26S subunit, non-ATPase 9
chr14_-_25935167 Show fit	1.29	ENSDART00000139855	g3bp1 NCBI UniProt Show fit	GTPase activating protein (SH3 domain) binding protein 1
chr23_+_38251864 Show fit	1.27	ENSDART00000183498 ENSDART00000129593	znf217 NCBI UniProt Show fit	zinc finger protein 217
chr13_-_12602920 Show fit	1.27	ENSDART00000102311	lrit3b NCBI UniProt Show fit	leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr11_+_17984354 Show fit	1.26	ENSDART00000179986	rpusd4 NCBI UniProt Show fit	RNA pseudouridylate synthase domain containing 4
chr23_+_39695827 Show fit	1.26	ENSDART00000113893 ENSDART00000186679	tmco4 NCBI UniProt Show fit	transmembrane and coiled-coil domains 4
chr3_+_22442445 Show fit	1.26	ENSDART00000190921	wnk4b NCBI UniProt Show fit	WNK lysine deficient protein kinase 4b
chr5_+_28497956 Show fit	1.25	ENSDART00000191935	nfr NCBI UniProt Show fit	notochord formation related
chr4_+_13901458 Show fit	1.25	ENSDART00000137549	pphln1 NCBI UniProt Show fit	periphilin 1
chr17_+_8799451 Show fit	1.25	ENSDART00000189814 ENSDART00000191577	tonsl NCBI UniProt Show fit	tonsoku-like, DNA repair protein
chr2_+_41526904 Show fit	1.25	ENSDART00000127520	acvr1l NCBI UniProt Show fit	activin A receptor, type 1 like
chr6_-_8311044 Show fit	1.25	ENSDART00000129674	slc44a2 NCBI UniProt Show fit	solute carrier family 44 (choline transporter), member 2
chr3_+_45365098 Show fit	1.25	ENSDART00000052746 ENSDART00000156555	ube2ia NCBI UniProt Show fit	ubiquitin-conjugating enzyme E2Ia
chr16_+_23961276 Show fit	1.24	ENSDART00000192754	apoeb NCBI UniProt Show fit	apolipoprotein Eb
chr20_-_20931197 Show fit	1.24	ENSDART00000152726	btbd6b NCBI UniProt Show fit	BTB (POZ) domain containing 6b
chr6_-_40922971 Show fit	1.23	ENSDART00000155363	sfi1 NCBI UniProt Show fit	SFI1 centrin binding protein
chr5_-_45958838 Show fit	1.23	ENSDART00000135072	poc5 NCBI UniProt Show fit	POC5 centriolar protein homolog (Chlamydomonas)
chr17_-_25649079 Show fit	1.22	ENSDART00000130955	ppp1cb NCBI UniProt Show fit	protein phosphatase 1, catalytic subunit, beta isozyme
chr8_+_50953776 Show fit	1.22	ENSDART00000013870	zgc:56596 NCBI UniProt Show fit	zgc:56596
chr5_+_60590796 Show fit	1.21	ENSDART00000159859	tmem132e NCBI UniProt Show fit	transmembrane protein 132E
chr23_+_1029450 Show fit	1.21	ENSDART00000189196	si:zfos-905g2.1 NCBI UniProt Show fit	si:zfos-905g2.1
chr3_-_38918697 Show fit	1.21	ENSDART00000145630	si:dkey-106c17.2 NCBI UniProt Show fit	si:dkey-106c17.2
chr10_-_22803740 Show fit	1.21	ENSDART00000079469 ENSDART00000187968 ENSDART00000122543	pcolcea NCBI UniProt Show fit	procollagen C-endopeptidase enhancer a
chr19_+_6990970 Show fit	1.21	ENSDART00000158758 ENSDART00000160482 ENSDART00000193566	kifc1 NCBI UniProt Show fit	kinesin family member C1
chr3_-_39695856 Show fit	1.20	ENSDART00000148247	b9d1 NCBI UniProt Show fit	B9 protein domain 1
chr21_-_15200556 Show fit	1.20	ENSDART00000141809	sfswap NCBI UniProt Show fit	splicing factor SWAP
chr4_+_9177997 Show fit	1.20	ENSDART00000057254 ENSDART00000154614	nfyba NCBI UniProt Show fit	nuclear transcription factor Y, beta a
chr8_+_28259347 Show fit	1.20	ENSDART00000110857	fam212b NCBI UniProt Show fit	family with sequence similarity 212, member B
chr6_-_43283122 Show fit	1.20	ENSDART00000186022	frmd4ba NCBI UniProt Show fit	FERM domain containing 4Ba
chr7_-_51368681 Show fit	1.19	ENSDART00000146385	arhgap36 NCBI UniProt Show fit	Rho GTPase activating protein 36
chr5_-_41307550 Show fit	1.19	ENSDART00000143446	npr3 NCBI UniProt Show fit	natriuretic peptide receptor 3
chr20_+_13883131 Show fit	1.19	ENSDART00000003248 ENSDART00000152611	nek2 NCBI UniProt Show fit	NIMA-related kinase 2
chr17_-_11439815 Show fit	1.18	ENSDART00000130105	psma3 NCBI UniProt Show fit	proteasome subunit alpha 3
chr3_+_13848226 Show fit	1.18	ENSDART00000184342	ilf3b NCBI UniProt Show fit	interleukin enhancer binding factor 3b
chr17_+_24722646 Show fit	1.18	ENSDART00000138356	mtfr1l NCBI UniProt Show fit	mitochondrial fission regulator 1-like
chr2_+_6253246 Show fit	1.17	ENSDART00000058256 ENSDART00000076700	zp3b NCBI UniProt Show fit	zona pellucida glycoprotein 3b
chr10_+_7593185 Show fit	1.17	ENSDART00000162617 ENSDART00000162590 ENSDART00000171744	ppp2cb NCBI UniProt Show fit	protein phosphatase 2, catalytic subunit, beta isozyme
chr7_+_29167744 Show fit	1.17	ENSDART00000076345	slc38a8b NCBI UniProt Show fit	solute carrier family 38, member 8b
chr15_-_3736773 Show fit	1.17	ENSDART00000090624	lpar6a NCBI UniProt Show fit	lysophosphatidic acid receptor 6a
chr3_+_53317040 Show fit	1.16	ENSDART00000011780	xab2 NCBI UniProt Show fit	XPA binding protein 2
chr2_-_5723786 Show fit	1.16	ENSDART00000100924	cwc25 NCBI UniProt Show fit	CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr19_+_45962016 Show fit	1.16	ENSDART00000169710	utp23 NCBI UniProt Show fit	UTP23, small subunit (SSU) processome component, homolog (yeast)
chr21_+_43702016 Show fit	1.16	ENSDART00000017176	dkc1 NCBI UniProt Show fit	dyskeratosis congenita 1, dyskerin
chr10_+_16092671 Show fit	1.15	ENSDART00000182761 ENSDART00000154835	megf10 NCBI UniProt Show fit	multiple EGF-like-domains 10
chr10_+_8197827 Show fit	1.15	ENSDART00000026244	mtrex NCBI UniProt Show fit	Mtr4 exosome RNA helicase
chr13_+_48359573 Show fit	1.14	ENSDART00000161959 ENSDART00000165311	msh6 NCBI UniProt Show fit	mutS homolog 6 (E. coli)
chr20_-_36408836 Show fit	1.14	ENSDART00000076419	lbr NCBI UniProt Show fit	lamin B receptor
chr5_-_63302944 Show fit	1.14	ENSDART00000047110	gsnb NCBI UniProt Show fit	gelsolin b
chr17_+_21295132 Show fit	1.14	ENSDART00000103845	eno4 NCBI UniProt Show fit	enolase family member 4
chr10_-_36691681 Show fit	1.13	ENSDART00000122375	mrpl48 NCBI UniProt Show fit	mitochondrial ribosomal protein L48
chr23_-_24952264 Show fit	1.13	ENSDART00000192085	zbtb48 NCBI UniProt Show fit	zinc finger and BTB domain containing 48
chr25_-_35956344 Show fit	1.13	ENSDART00000066987	mphosph6 NCBI UniProt Show fit	M-phase phosphoprotein 6
chr6_-_8392104 Show fit	1.13	ENSDART00000081561 ENSDART00000181178	ilf3a NCBI UniProt Show fit	interleukin enhancer binding factor 3a
chr19_-_7540821 Show fit	1.13	ENSDART00000143958	lix1l NCBI UniProt Show fit	limb and CNS expressed 1 like
chr20_-_37490612 Show fit	1.12	ENSDART00000185458	si:ch211-202p1.5 NCBI UniProt Show fit	si:ch211-202p1.5
chr23_+_31912882 Show fit	1.12	ENSDART00000140505	armc1l NCBI UniProt Show fit	armadillo repeat containing 1, like
chr7_+_22313533 Show fit	1.11	ENSDART00000123457	TMEM102 NCBI UniProt Show fit	si:dkey-11f12.2
chr10_+_17235370 Show fit	1.11	ENSDART00000038780	sppl3 NCBI UniProt Show fit	signal peptide peptidase 3
chr11_-_30634286 Show fit	1.11	ENSDART00000191019	zgc:153665 NCBI UniProt Show fit	zgc:153665
chr24_-_4450238 Show fit	1.11	ENSDART00000066835	fzd8a NCBI UniProt Show fit	frizzled class receptor 8a
chr20_+_46513651 Show fit	1.11	ENSDART00000152977	zc3h14 NCBI UniProt Show fit	zinc finger CCCH-type containing 14
chr24_+_37800102 Show fit	1.10	ENSDART00000187591	telo2 NCBI UniProt Show fit	TEL2, telomere maintenance 2, homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-43p13.5+uncx

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	6.1	GO:0000012	single strand break repair(GO:0000012)
1.0	4.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.7	2.2	GO:0048785	hatching gland development(GO:0048785)
0.7	2.2	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.7	2.8	GO:0036306	embryonic heart tube elongation(GO:0036306)
0.6	1.9	GO:1904983	transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.6	1.8	GO:0031441	negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.6	1.7	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.5	2.1	GO:0048890	epidermal cell fate specification(GO:0009957) lateral line ganglion development(GO:0048890)
0.5	1.6	GO:0098924	retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.5	2.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.5	1.5	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.5	1.5	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.4	1.7	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.4	1.2	GO:0071831	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.4	2.0	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.4	1.6	GO:0009080	alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.4	2.0	GO:0046084	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.4	1.2	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.4	1.9	GO:0032776	DNA methylation on cytosine(GO:0032776)
0.4	1.1	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.4	2.6	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.4	1.5	GO:0010259	multicellular organism aging(GO:0010259)
0.4	3.0	GO:0006895	Golgi to endosome transport(GO:0006895)
0.4	1.1	GO:0060898	spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.4	1.1	GO:0021512	spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.4	2.2	GO:0000455	enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.4	1.1	GO:0003097	renal water homeostasis(GO:0003091) renal water transport(GO:0003097) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.4	1.1	GO:1903334	regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.3	3.1	GO:0001709	cell fate determination(GO:0001709)
0.3	1.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.3	1.6	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
0.3	1.6	GO:0003261	cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.3	1.9	GO:0048795	swim bladder morphogenesis(GO:0048795)
0.3	1.3	GO:0035124	embryonic caudal fin morphogenesis(GO:0035124)
0.3	1.2	GO:0015871	choline transport(GO:0015871)
0.3	0.9	GO:0045002	double-strand break repair via single-strand annealing(GO:0045002)
0.3	0.9	GO:0042373	vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.3	0.8	GO:0010658	negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.3	1.9	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.3	1.6	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.3	1.1	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3	1.0	GO:1904590	regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.3	0.8	GO:1901232	regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.3	1.3	GO:0070294	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.3	1.3	GO:0097355	protein localization to heterochromatin(GO:0097355)
0.2	0.7	GO:0071918	urea transmembrane transport(GO:0071918)
0.2	1.0	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.2	2.2	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.2	3.8	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.2	1.0	GO:0070987	error-free translesion synthesis(GO:0070987)
0.2	2.1	GO:0072395	signal transduction involved in cell cycle checkpoint(GO:0072395)
0.2	0.9	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.2	0.9	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.2	4.7	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.2	1.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2	0.7	GO:0014814	regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.2	0.7	GO:0043416	regulation of skeletal muscle tissue regeneration(GO:0043416)
0.2	1.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.2	1.7	GO:0044528	regulation of mitochondrial mRNA stability(GO:0044528)
0.2	2.1	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661)
0.2	1.4	GO:0033687	osteoblast proliferation(GO:0033687)
0.2	1.0	GO:1900145	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.2	1.6	GO:2000290	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.2	2.0	GO:0051601	exocyst localization(GO:0051601)
0.2	1.0	GO:0060295	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2	1.0	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2	1.8	GO:0060004	reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.2	0.7	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.2	0.5	GO:0016045	detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2	0.5	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.2	1.8	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.2	1.6	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.2	0.7	GO:0061033	lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.2	0.9	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
0.2	0.7	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2	4.1	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.2	1.0	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.2	0.7	GO:1990511	piRNA biosynthetic process(GO:1990511)
0.2	0.3	GO:0060283	negative regulation of oocyte development(GO:0060283)
0.2	0.5	GO:0036159	inner dynein arm assembly(GO:0036159)
0.2	1.5	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.2	0.6	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.2	2.6	GO:0007339	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2	5.6	GO:0000266	mitochondrial fission(GO:0000266)
0.1	3.7	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1	1.8	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.1	1.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.9	GO:0035881	amacrine cell differentiation(GO:0035881)
0.1	1.4	GO:0046548	retinal rod cell development(GO:0046548)
0.1	1.1	GO:0032889	regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1	0.8	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1	1.7	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1	1.0	GO:0090497	mesenchymal cell migration(GO:0090497)
0.1	0.4	GO:0007414	axonal defasciculation(GO:0007414)
0.1	1.2	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1	2.3	GO:0032204	regulation of telomere maintenance(GO:0032204)
0.1	0.9	GO:0033278	cell proliferation in midbrain(GO:0033278)
0.1	0.5	GO:0089709	L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1	1.3	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1	1.9	GO:0043248	proteasome assembly(GO:0043248)
0.1	1.7	GO:0032481	positive regulation of type I interferon production(GO:0032481)
0.1	3.2	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	0.6	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	1.6	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.1	0.9	GO:1903828	negative regulation of cellular protein localization(GO:1903828)
0.1	1.1	GO:0006465	signal peptide processing(GO:0006465)
0.1	1.7	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1	1.2	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1	0.6	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.1	0.6	GO:0032289	central nervous system myelin formation(GO:0032289)
0.1	1.8	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1	2.3	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.1	0.4	GO:0051958	folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1	0.8	GO:0035912	aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.1	1.3	GO:1903318	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.1	1.7	GO:0051383	kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.1	0.9	GO:1902262	apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1	0.3	GO:0048389	intermediate mesoderm development(GO:0048389)
0.1	0.9	GO:0090224	regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.1	3.4	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1	2.4	GO:0021983	pituitary gland development(GO:0021983)
0.1	1.0	GO:0044854	membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1	1.7	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.1	0.4	GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1	1.8	GO:0060021	palate development(GO:0060021)
0.1	0.6	GO:0048011	neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1	1.0	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.1	3.3	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1	0.8	GO:0006102	isocitrate metabolic process(GO:0006102)
0.1	1.1	GO:0007004	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.1	0.7	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	0.3	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.1	1.4	GO:0051445	regulation of meiotic cell cycle(GO:0051445)
0.1	0.1	GO:0097242	regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.1	1.3	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.1	1.1	GO:0090309	methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1	2.3	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.1	1.3	GO:0006596	polyamine biosynthetic process(GO:0006596)
0.1	0.9	GO:0070475	rRNA base methylation(GO:0070475)
0.1	1.7	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1	0.9	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	0.6	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.2	GO:1900180	snRNA modification(GO:0040031) regulation of protein localization to nucleus(GO:1900180)
0.1	0.9	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1	1.4	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	0.5	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	0.3	GO:0048210	Golgi vesicle fusion to target membrane(GO:0048210)
0.1	0.9	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.1	0.4	GO:0002143	tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1	1.9	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.1	2.7	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1	0.9	GO:0016926	protein desumoylation(GO:0016926)
0.1	0.6	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.1	1.2	GO:0060038	cardiac muscle cell proliferation(GO:0060038)
0.1	1.2	GO:0031297	replication fork processing(GO:0031297)
0.1	0.7	GO:1900052	regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1	0.5	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.2	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1	3.2	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.1	1.2	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.1	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.1	1.8	GO:0038061	NIK/NF-kappaB signaling(GO:0038061)
0.1	0.4	GO:0016572	histone phosphorylation(GO:0016572)
0.1	0.7	GO:0006032	chitin catabolic process(GO:0006032)
0.1	0.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	1.8	GO:0051014	actin filament severing(GO:0051014)
0.1	0.5	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.5	GO:1902038	positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1	0.8	GO:0071156	regulation of cell cycle arrest(GO:0071156)
0.1	1.8	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.1	0.6	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	0.3	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.1	0.5	GO:0006450	regulation of translational fidelity(GO:0006450)
0.1	1.0	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.1	0.2	GO:0030220	platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1	1.6	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	0.3	GO:0090243	fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1	1.0	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	2.1	GO:0061386	closure of optic fissure(GO:0061386)
0.1	1.4	GO:0070831	basement membrane assembly(GO:0070831)
0.1	1.2	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.1	0.3	GO:1990108	protein linear deubiquitination(GO:1990108)
0.1	0.8	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.5	GO:0046146	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.3	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.9	GO:0014823	response to activity(GO:0014823)
0.0	0.9	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	1.0	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	1.5	GO:0007050	cell cycle arrest(GO:0007050)
0.0	1.0	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	2.4	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.4	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	1.1	GO:1902653	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0	2.9	GO:0034504	protein localization to nucleus(GO:0034504)
0.0	0.3	GO:0065005	plasma lipoprotein particle assembly(GO:0034377) protein-lipid complex assembly(GO:0065005)
0.0	0.4	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.6	GO:0060968	regulation of gene silencing(GO:0060968)
0.0	2.5	GO:0021515	cell differentiation in spinal cord(GO:0021515)
0.0	0.2	GO:0006154	adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0	0.5	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.3	GO:0034508	centromere complex assembly(GO:0034508)
0.0	1.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.4	GO:0032088	negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0	0.2	GO:0015744	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0	0.3	GO:0032917	spermidine metabolic process(GO:0008216) polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0	0.1	GO:0036076	ligamentous ossification(GO:0036076)
0.0	3.4	GO:0031018	endocrine pancreas development(GO:0031018)
0.0	1.7	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	2.4	GO:0051607	defense response to virus(GO:0051607)
0.0	0.7	GO:0031033	myosin filament organization(GO:0031033)
0.0	1.7	GO:1902275	regulation of chromatin organization(GO:1902275)
0.0	0.7	GO:0051028	mRNA transport(GO:0051028)
0.0	0.8	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	3.6	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.8	GO:0060997	dendritic spine morphogenesis(GO:0060997)
0.0	0.4	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.4	GO:0061300	cerebellum vasculature development(GO:0061300)
0.0	1.3	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.6	GO:2000404	regulation of T cell migration(GO:2000404)
0.0	0.0	GO:2000401	regulation of lymphocyte migration(GO:2000401)
0.0	1.1	GO:0031103	axon regeneration(GO:0031103)
0.0	0.4	GO:0018198	peptidyl-cysteine modification(GO:0018198)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.2	GO:2000780	negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0	1.2	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.8	GO:0006623	protein targeting to vacuole(GO:0006623)
0.0	0.4	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0	1.3	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.4	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0	0.1	GO:0007141	male meiosis I(GO:0007141)
0.0	0.8	GO:0042255	ribosome assembly(GO:0042255)
0.0	2.9	GO:0050768	negative regulation of neurogenesis(GO:0050768)
0.0	0.7	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.6	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.3	GO:0098719	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	1.0	GO:0006289	nucleotide-excision repair(GO:0006289)
0.0	0.7	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	1.4	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.5	GO:0003401	axis elongation(GO:0003401)
0.0	0.2	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.8	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	1.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.4	GO:0002455	humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0	0.7	GO:0009615	response to virus(GO:0009615)
0.0	0.4	GO:0006228	UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0	0.2	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.3	GO:0051654	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.0	0.5	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.3	GO:0046549	retinal cone cell development(GO:0046549)
0.0	8.4	GO:0008380	RNA splicing(GO:0008380)
0.0	2.8	GO:0006364	rRNA processing(GO:0006364)
0.0	0.5	GO:0032526	response to retinoic acid(GO:0032526)
0.0	0.1	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0	1.1	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
0.0	1.8	GO:0070121	Kupffer's vesicle development(GO:0070121)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.5	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.0	0.8	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.1	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.7	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	1.1	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	1.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:2000580	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.4	GO:0070672	interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0	0.3	GO:0007340	acrosome reaction(GO:0007340)
0.0	1.0	GO:0042254	ribosome biogenesis(GO:0042254)
0.0	0.4	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	1.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.2	GO:0046341	CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.7	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.0	0.3	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.3	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	1.3	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.4	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.3	GO:0008354	germ cell migration(GO:0008354)
0.0	0.5	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	1.0	GO:0030166	proteoglycan biosynthetic process(GO:0030166)
0.0	0.5	GO:0055064	chloride ion homeostasis(GO:0055064)
0.0	0.6	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.3	GO:0042476	odontogenesis(GO:0042476)
0.0	0.5	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.8	GO:0017144	drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0	0.1	GO:0046462	phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0	0.3	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.0	GO:0010456	cell proliferation in dorsal spinal cord(GO:0010456)
0.0	0.1	GO:0061055	myotome development(GO:0061055)
0.0	0.3	GO:0002761	regulation of myeloid leukocyte differentiation(GO:0002761)
0.0	0.6	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.5	GO:0010324	membrane invagination(GO:0010324)
0.0	0.8	GO:0031016	pancreas development(GO:0031016)
0.0	0.7	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	5.7	GO:0043066	negative regulation of apoptotic process(GO:0043066)
0.0	0.3	GO:0016925	protein sumoylation(GO:0016925)
0.0	1.9	GO:0000209	protein polyubiquitination(GO:0000209)
0.0	1.1	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	1.4	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.3	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.0	0.6	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.1	GO:0031048	chromatin silencing by small RNA(GO:0031048)
0.0	0.3	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.2	GO:0007164	establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.0	1.1	GO:0008033	tRNA processing(GO:0008033)
0.0	0.0	GO:0018008	N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0	0.3	GO:0097202	activation of cysteine-type endopeptidase activity(GO:0097202)
0.0	0.2	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.9	GO:0031098	stress-activated protein kinase signaling cascade(GO:0031098)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0034457	Mpp10 complex(GO:0034457)
0.4	1.1	GO:0032301	MutSalpha complex(GO:0032301)
0.4	1.1	GO:0097189	apoptotic body(GO:0097189)
0.4	1.1	GO:0072380	TRC complex(GO:0072380)
0.3	1.7	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.3	1.4	GO:0033186	CAF-1 complex(GO:0033186)
0.3	1.3	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.3	1.2	GO:0031429	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.3	1.1	GO:0071556	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3	1.1	GO:0070209	ASTRA complex(GO:0070209)
0.3	0.8	GO:1990072	TRAPPIII protein complex(GO:1990072)
0.3	1.0	GO:0035301	Hedgehog signaling complex(GO:0035301)
0.3	1.3	GO:0000811	GINS complex(GO:0000811)
0.3	1.3	GO:0070724	BMP receptor complex(GO:0070724)
0.2	2.7	GO:0035101	FACT complex(GO:0035101)
0.2	0.9	GO:0070319	Golgi to plasma membrane transport vesicle(GO:0070319)
0.2	1.8	GO:0035060	brahma complex(GO:0035060)
0.2	0.9	GO:0097268	cytoophidium(GO:0097268)
0.2	0.9	GO:0005880	nuclear microtubule(GO:0005880)
0.2	0.6	GO:0031310	integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2	2.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.2	2.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.2	1.4	GO:0005614	interstitial matrix(GO:0005614)
0.2	1.6	GO:0000974	Prp19 complex(GO:0000974)
0.2	0.9	GO:0070390	transcription export complex 2(GO:0070390)
0.2	5.7	GO:0043186	P granule(GO:0043186)
0.2	0.5	GO:0019185	snRNA-activating protein complex(GO:0019185)
0.2	2.7	GO:0005682	U5 snRNP(GO:0005682)
0.1	1.0	GO:0000439	core TFIIH complex(GO:0000439)
0.1	3.0	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.1	1.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.1	0.6	GO:0032584	growth cone membrane(GO:0032584)
0.1	1.5	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	1.0	GO:0071818	BAT3 complex(GO:0071818)
0.1	2.2	GO:0036038	MKS complex(GO:0036038)
0.1	0.7	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1	0.9	GO:1990130	Iml1 complex(GO:1990130)
0.1	1.3	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	1.0	GO:0032797	SMN complex(GO:0032797)
0.1	1.0	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	0.3	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	1.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	1.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	2.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	1.4	GO:0070187	telosome(GO:0070187)
0.1	5.1	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.1	0.5	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	0.6	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	1.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	2.4	GO:0000145	exocyst(GO:0000145)
0.1	1.3	GO:0045180	basal cortex(GO:0045180)
0.1	0.4	GO:0033263	CORVET complex(GO:0033263)
0.1	2.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	1.5	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	1.1	GO:0002102	podosome(GO:0002102)
0.1	0.8	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	0.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	0.5	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.1	0.8	GO:0072546	ER membrane protein complex(GO:0072546)
0.1	0.7	GO:0005686	U2 snRNP(GO:0005686)
0.1	1.2	GO:0000813	ESCRT I complex(GO:0000813)
0.1	0.7	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	1.2	GO:0005839	proteasome core complex(GO:0005839)
0.1	3.6	GO:0016592	mediator complex(GO:0016592)
0.1	0.8	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	0.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	1.0	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.1	0.3	GO:0055087	Ski complex(GO:0055087)
0.1	0.7	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.5	GO:0071011	precatalytic spliceosome(GO:0071011)
0.1	0.5	GO:0032021	NELF complex(GO:0032021)
0.1	0.4	GO:0034990	nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1	1.0	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	1.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.6	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	1.0	GO:0032039	integrator complex(GO:0032039)
0.0	0.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0043514	interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0	2.1	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	1.0	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.5	GO:0034451	centriolar satellite(GO:0034451)
0.0	1.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	2.5	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.4	GO:0045171	intercellular bridge(GO:0045171)
0.0	1.6	GO:0005684	U2-type spliceosomal complex(GO:0005684)
0.0	0.6	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	4.6	GO:0016607	nuclear speck(GO:0016607)
0.0	1.7	GO:0005657	replication fork(GO:0005657)
0.0	1.6	GO:0005795	Golgi stack(GO:0005795)
0.0	1.0	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.6	GO:0035869	ciliary transition zone(GO:0035869)
0.0	0.5	GO:0071564	npBAF complex(GO:0071564)
0.0	0.8	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.6	GO:0005869	dynactin complex(GO:0005869)
0.0	0.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	1.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.4	GO:0071782	endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0	2.4	GO:0005681	spliceosomal complex(GO:0005681)
0.0	1.2	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.7	GO:0033290	eukaryotic 48S preinitiation complex(GO:0033290)
0.0	2.0	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.3	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	2.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	2.3	GO:0019867	mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0	1.3	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.4	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	1.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	1.6	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.4	GO:0000815	ESCRT III complex(GO:0000815)
0.0	3.5	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	2.6	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	1.5	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.4	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.8	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.5	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.3	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	1.0	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.5	GO:0036464	cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0	0.3	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.0	0.3	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	1.5	GO:0031228	integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0	0.3	GO:0042627	chylomicron(GO:0042627)
0.0	2.3	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	4.7	GO:0005730	nucleolus(GO:0005730)
0.0	2.1	GO:0044309	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0	1.9	GO:0000786	nucleosome(GO:0000786)
0.0	0.4	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.0	GO:0097255	R2TP complex(GO:0097255)
0.0	0.1	GO:0000938	GARP complex(GO:0000938)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.6	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	2.2	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.9	GO:0005581	collagen trimer(GO:0005581)
0.0	3.6	GO:0031966	mitochondrial membrane(GO:0031966)
0.0	0.4	GO:0030496	midbody(GO:0030496)
0.0	1.0	GO:0005604	basement membrane(GO:0005604)
0.0	4.1	GO:0005694	chromosome(GO:0005694)
0.0	65.1	GO:0005634	nucleus(GO:0005634)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.9	2.6	GO:0016748	succinyltransferase activity(GO:0016748)
0.7	2.8	GO:0061656	SUMO conjugating enzyme activity(GO:0061656)
0.6	3.1	GO:0009374	biotin binding(GO:0009374)
0.4	5.8	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4	2.6	GO:0008158	hedgehog receptor activity(GO:0008158)
0.4	1.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.4	1.6	GO:0003884	D-amino-acid oxidase activity(GO:0003884)
0.4	1.6	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.4	1.1	GO:0032357	guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.4	1.1	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.4	3.2	GO:0043515	kinetochore binding(GO:0043515)
0.4	1.8	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.4	1.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.3	2.4	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.3	1.3	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.3	1.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.3	0.9	GO:0070336	flap-structured DNA binding(GO:0070336)
0.3	1.7	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.3	0.9	GO:0000035	acyl binding(GO:0000035)
0.3	0.9	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3	0.8	GO:0004904	interferon receptor activity(GO:0004904)
0.3	1.1	GO:0008488	gamma-glutamyl carboxylase activity(GO:0008488)
0.3	1.0	GO:0050333	thiamin-triphosphatase activity(GO:0050333)
0.2	1.7	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	0.9	GO:0003883	CTP synthase activity(GO:0003883)
0.2	1.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.2	0.7	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2	0.7	GO:0009384	UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.2	2.0	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.2	0.9	GO:0070182	DNA polymerase binding(GO:0070182)
0.2	4.1	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.2	1.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.2	1.9	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.2	1.0	GO:0003977	UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.2	1.3	GO:0004329	formate-tetrahydrofolate ligase activity(GO:0004329)
0.2	0.6	GO:0043621	protein self-association(GO:0043621)
0.2	1.7	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.2	0.5	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.2	0.7	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.2	0.4	GO:1990715	mRNA CDS binding(GO:1990715)
0.2	1.9	GO:0047676	arachidonate-CoA ligase activity(GO:0047676)
0.2	2.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	1.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.2	1.7	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2	0.8	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.2	1.6	GO:0035925	AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2	0.6	GO:0004064	arylesterase activity(GO:0004064)
0.2	2.6	GO:0032190	acrosin binding(GO:0032190)
0.2	0.8	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.4	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1	2.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.1	1.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	1.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	1.9	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.1	1.9	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	1.7	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	2.6	GO:0008143	poly(A) binding(GO:0008143)
0.1	0.6	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	5.2	GO:0003727	single-stranded RNA binding(GO:0003727)
0.1	0.4	GO:0008518	reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1	0.3	GO:0005183	gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.1	1.9	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	1.1	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.1	1.1	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1	0.4	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1	1.3	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.8	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.5	GO:0048763	ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1	1.4	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	0.4	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	1.4	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	2.6	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	1.0	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1	0.3	GO:0034185	apolipoprotein binding(GO:0034185)
0.1	1.8	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.8	GO:0032977	membrane insertase activity(GO:0032977)
0.1	2.3	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1	1.1	GO:0045503	dynein light chain binding(GO:0045503)
0.1	1.4	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	3.1	GO:0003684	damaged DNA binding(GO:0003684)
0.1	6.5	GO:0003724	RNA helicase activity(GO:0003724)
0.1	1.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.1	0.8	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	1.3	GO:0019869	chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1	0.8	GO:0016805	dipeptidase activity(GO:0016805)
0.1	0.5	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.9	GO:0004526	ribonuclease P activity(GO:0004526)
0.1	0.9	GO:1990404	protein ADP-ribosylase activity(GO:1990404)
0.1	0.3	GO:1904121	phosphatidylethanolamine transporter activity(GO:1904121)
0.1	0.6	GO:0005113	patched binding(GO:0005113)
0.1	1.6	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	2.8	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.1	0.3	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	1.4	GO:0030515	snoRNA binding(GO:0030515)
0.1	1.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.5	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1	0.7	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	3.3	GO:0042826	histone deacetylase binding(GO:0042826)
0.1	0.7	GO:0004568	chitinase activity(GO:0004568)
0.1	1.3	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.2	GO:0004377	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1	1.3	GO:0005003	ephrin receptor activity(GO:0005003)
0.1	0.8	GO:0005537	mannose binding(GO:0005537)
0.1	0.7	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	1.6	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.5	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	1.0	GO:0035497	cAMP response element binding(GO:0035497)
0.1	1.1	GO:0015026	coreceptor activity(GO:0015026)
0.1	2.7	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	1.1	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.4	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1	1.4	GO:0042162	telomeric DNA binding(GO:0042162)
0.1	0.3	GO:0046966	vitamin D receptor binding(GO:0042809) thyroid hormone receptor binding(GO:0046966)
0.1	0.9	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.1	1.0	GO:0070411	I-SMAD binding(GO:0070411)
0.1	0.4	GO:0043035	chromatin insulator sequence binding(GO:0043035)
0.0	1.0	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.3	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.2	GO:0042164	interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0	2.4	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.5	GO:0052795	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.3	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	0.2	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.7	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.6	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	3.1	GO:0031625	ubiquitin protein ligase binding(GO:0031625)
0.0	0.2	GO:0043394	glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0	2.0	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	1.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.2	GO:0015117	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0	0.3	GO:0019809	spermidine binding(GO:0019809)
0.0	0.7	GO:0031729	CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0	0.2	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.6	GO:0061608	nuclear import signal receptor activity(GO:0061608)
0.0	0.2	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.2	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.6	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.6	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.6	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.7	GO:0097602	cullin family protein binding(GO:0097602)
0.0	1.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	1.4	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	1.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	2.0	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.2	GO:0008118	N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0	0.7	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.6	GO:0051371	muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0	0.2	GO:0016793	dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.0	0.9	GO:0030165	PDZ domain binding(GO:0030165)
0.0	1.1	GO:0004629	phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0	0.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	1.2	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	2.6	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	1.9	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.3	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.4	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	2.2	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.6	GO:0051119	sugar transmembrane transporter activity(GO:0051119)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295)
0.0	0.3	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.0	2.0	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.2	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.3	GO:0031720	haptoglobin binding(GO:0031720)
0.0	0.4	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.4	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	1.4	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.6	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.4	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.5	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.5	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.2	GO:0034584	piRNA binding(GO:0034584)
0.0	0.7	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.1	GO:0050699	WW domain binding(GO:0050699)
0.0	0.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.7	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	3.4	GO:0042802	identical protein binding(GO:0042802)
0.0	0.5	GO:0031072	heat shock protein binding(GO:0031072)
0.0	0.6	GO:0009055	electron carrier activity(GO:0009055)
0.0	0.3	GO:0002039	p53 binding(GO:0002039)
0.0	35.6	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.4	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	2.8	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0034979	NAD-dependent protein deacetylase activity(GO:0034979)
0.0	1.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.4	GO:0016307	phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.8	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0	0.4	GO:0000049	tRNA binding(GO:0000049)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.0	GO:0019107	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0	0.4	GO:0071855	neuropeptide receptor binding(GO:0071855)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.5	PID AURORA B PATHWAY	Aurora B signaling
0.1	5.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	8.2	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	1.6	PID ARF 3PATHWAY	Arf1 pathway
0.1	2.9	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	0.7	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	1.4	PID AURORA A PATHWAY	Aurora A signaling
0.1	1.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	1.4	PID ARF6 PATHWAY	Arf6 signaling events
0.1	1.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	0.8	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	2.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.1	1.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	0.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	1.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	1.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	0.9	PID ATM PATHWAY	ATM pathway
0.1	0.9	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.8	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.9	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.2	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	2.1	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.0	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	1.1	PID BMP PATHWAY	BMP receptor signaling
0.0	1.1	PID FGF PATHWAY	FGF signaling pathway
0.0	1.7	PID P73PATHWAY	p73 transcription factor network
0.0	0.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	0.5	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	3.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.7	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	2.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	1.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.2	3.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	3.1	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.2	1.7	REACTOME BASE EXCISION REPAIR	Genes involved in Base Excision Repair
0.2	5.7	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1	4.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	3.0	REACTOME KINESINS	Genes involved in Kinesins
0.1	2.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	9.0	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	1.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	3.4	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.1	1.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	5.3	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	1.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.7	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	2.1	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1	1.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	2.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	0.6	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.6	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	0.8	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	0.9	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.1	1.6	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	1.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	0.4	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.1	0.7	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	0.9	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	1.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	0.8	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.2	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.0	1.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	3.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.6	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.4	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	1.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.9	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.8	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.6	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.7	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	1.2	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.9	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.0	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.5	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	1.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.7	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.7	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.1	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis

Results for si:dkey-43p13.5+uncx

Z-value: 1.19

Motif logo

Transcription factors associated with si:dkey-43p13.5+uncx

Activity-expression correlation:

Activity profile of si:dkey-43p13.5+uncx motif

Sorted Z-values of si:dkey-43p13.5+uncx motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-43p13.5+uncx

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: