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PRJEB1986: zebrafish developmental stages transcriptome

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Results for six6a+six6b

Z-value: 0.42

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Transcription factors associated with six6a+six6b

Gene Symbol Gene ID Gene Info
six6a
ENSDARG00000025187 SIX homeobox 6a
six6b
ENSDARG00000031316 SIX homeobox 6b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
six6bdr11_v1_chr20_-_20533865_205338650.853.8e-06Click!
six6adr11_v1_chr13_+_31603988_316039880.716.1e-04Click!

Activity profile of six6a+six6b motif

Sorted Z-values of six6a+six6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22310919 1.43 ENSDART00000108719
crygm2d10
crystallin, gamma M2d10
chr13_+_35745572 1.06 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr25_+_31277415 0.98 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr14_+_51098036 0.90 ENSDART00000184118
CABZ01078594.1

chr17_+_51627209 0.83 ENSDART00000056886
zgc:113142
zgc:113142
chr3_+_25154078 0.74 ENSDART00000156973
si:ch211-256m1.8
si:ch211-256m1.8
chr7_-_31932723 0.53 ENSDART00000014843
bdnf
brain-derived neurotrophic factor
chr3_+_50069204 0.52 ENSDART00000184243
zgc:103625
zgc:103625
chr10_-_25816558 0.51 ENSDART00000017240
postna
periostin, osteoblast specific factor a
chr10_-_43540196 0.49 ENSDART00000170891
si:ch73-215f7.1
si:ch73-215f7.1
chr22_-_10459880 0.45 ENSDART00000064801
ogn
osteoglycin
chr4_+_76637548 0.45 ENSDART00000133799
ms4a17a.9
membrane-spanning 4-domains, subfamily A, member 17A.9
chr11_-_31039533 0.44 ENSDART00000127355
ier2b
immediate early response 2b
chr14_+_50770537 0.43 ENSDART00000158723
sncb
synuclein, beta
chr8_-_12847483 0.43 ENSDART00000146186
si:dkey-104n9.1
si:dkey-104n9.1
chr7_+_20535869 0.41 ENSDART00000078181
zgc:158423
zgc:158423
chr2_+_47581997 0.40 ENSDART00000112579
scg2b
secretogranin II (chromogranin C), b
chr19_-_32710922 0.38 ENSDART00000004034
hpca
hippocalcin
chr8_+_2575993 0.38 ENSDART00000112914
si:ch211-51h9.7
si:ch211-51h9.7
chr16_+_6632969 0.37 ENSDART00000109276
sall3a
spalt-like transcription factor 3a
chr21_-_42007213 0.36 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gabrg2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_-_44946094 0.35 ENSDART00000036997
camk2n1a
calcium/calmodulin-dependent protein kinase II inhibitor 1a
chr3_-_21106093 0.35 ENSDART00000156566
maza
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr20_+_12702923 0.35 ENSDART00000163499
zgc:153383
zgc:153383
chr18_-_48755037 0.34 ENSDART00000109673
tirap
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
chr16_+_44906324 0.33 ENSDART00000074960
cd22
cd22 molecule
chr13_+_28819768 0.32 ENSDART00000191401
ENSDART00000188895
ENSDART00000101653
CU639469.1

chr1_+_1789357 0.31 ENSDART00000006449
atp1a1a.2
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 2
chr23_+_32335871 0.31 ENSDART00000149698
slc39a5
solute carrier family 39 (zinc transporter), member 5
chr1_+_34527213 0.30 ENSDART00000180483
klf12a
Kruppel-like factor 12a
chr16_+_9609721 0.30 ENSDART00000047920
enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr7_+_22767678 0.29 ENSDART00000137203
ponzr6
plac8 onzin related protein 6
chr9_+_50007556 0.29 ENSDART00000175587
slc38a11
solute carrier family 38, member 11
chr15_-_1822548 0.29 ENSDART00000082026
ENSDART00000180230
mmp28
matrix metallopeptidase 28
chr20_+_37383034 0.28 ENSDART00000134997
ENSDART00000145927
adgrg6
adhesion G protein-coupled receptor G6
chr12_+_47448558 0.28 ENSDART00000185689
ENSDART00000105328
fmn2b
formin 2b
chr23_-_7826849 0.27 ENSDART00000157612
myt1b
myelin transcription factor 1b
chr23_-_38497705 0.27 ENSDART00000109493
tshz2
teashirt zinc finger homeobox 2
chr15_-_31419805 0.26 ENSDART00000060111
or111-11
odorant receptor, family D, subfamily 111, member 11
chr7_+_6385664 0.26 ENSDART00000173144
si:ch73-368j24.17
si:ch73-368j24.17
chr15_-_2596125 0.25 ENSDART00000114923
dnajc30b
DnaJ (Hsp40) homolog, subfamily C, member 30b
chr9_-_19583704 0.25 ENSDART00000053218
tmprss3a
transmembrane protease, serine 3a
chr23_-_44226556 0.24 ENSDART00000149115
zgc:158659
zgc:158659
chr2_-_30249746 0.24 ENSDART00000124153
ENSDART00000142575
elocb
elongin C paralog b
chr2_-_30250311 0.24 ENSDART00000184144
elocb
elongin C paralog b
chr8_-_33114202 0.23 ENSDART00000098840
ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr24_+_2962988 0.22 ENSDART00000164449
eci2
enoyl-CoA delta isomerase 2
chr16_+_46492756 0.22 ENSDART00000105931
rpz5
rapunzel 5
chr5_-_57526807 0.21 ENSDART00000022866
pisd
phosphatidylserine decarboxylase
chr15_-_6946286 0.20 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr19_+_206835 0.20 ENSDART00000161137
scn1bb
sodium channel, voltage-gated, type I, beta b
chr10_-_24648228 0.20 ENSDART00000081834
ENSDART00000132830
stoml3b
stomatin (EPB72)-like 3b
chr14_-_17306261 0.20 ENSDART00000191747
jakmip1
janus kinase and microtubule interacting protein 1
chr23_+_37955041 0.19 ENSDART00000087148
cbln4
cerebellin 4 precursor
chr16_+_46492994 0.19 ENSDART00000134734
rpz5
rapunzel 5
chr16_-_36979592 0.19 ENSDART00000168443
snrnp48
small nuclear ribonucleoprotein 48 (U11/U12)
chr13_+_42544009 0.19 ENSDART00000145409
si:dkey-221j11.3
si:dkey-221j11.3
chr25_+_3306620 0.18 ENSDART00000182085
ENSDART00000034704
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr19_-_3925801 0.17 ENSDART00000129570
ENSDART00000163138
si:ch73-281i18.6
si:ch73-281i18.6
chr2_+_3881000 0.17 ENSDART00000081897
mpp7b
membrane protein, palmitoylated 7b (MAGUK p55 subfamily member 7)
chr15_+_15390882 0.17 ENSDART00000062024
ca4b
carbonic anhydrase IV b
chr7_+_20344486 0.17 ENSDART00000134004
ENSDART00000139685
ponzr1
plac8 onzin related protein 1
chr10_+_21395298 0.17 ENSDART00000138703
trpc7a
transient receptor potential cation channel, subfamily C, member 7a
chr8_+_52701811 0.17 ENSDART00000179692
bcl2l16
BCL2 like 16
chr23_+_16831063 0.16 ENSDART00000104782
zgc:173570
zgc:173570
chr9_-_53817143 0.16 ENSDART00000148764
ENSDART00000075537
ednrbb
endothelin receptor type Bb
chr5_+_36661058 0.15 ENSDART00000125653
capns1a
calpain, small subunit 1 a
chr21_+_45502621 0.15 ENSDART00000166719
si:dkey-223p19.2
si:dkey-223p19.2
chr10_+_23060391 0.15 ENSDART00000079711
slc25a1a
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr6_-_28980756 0.15 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr23_-_42232124 0.15 ENSDART00000149944
gpx7
glutathione peroxidase 7
chr2_+_30249977 0.15 ENSDART00000109160
ENSDART00000135171
tmem70
transmembrane protein 70
chr19_-_3906369 0.15 ENSDART00000160299
ENSDART00000169205
si:ch73-281i18.4
si:ch73-281i18.4
chr2_-_27775236 0.14 ENSDART00000187983
XKR4
zgc:123035
chr14_+_22467672 0.14 ENSDART00000079409
ENSDART00000136597
nudt22
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr3_+_23726148 0.14 ENSDART00000174580
hoxb3a
homeobox B3a
chr2_+_53357953 0.14 ENSDART00000187577
celf5b
cugbp, Elav-like family member 5b
chr18_+_32979166 0.14 ENSDART00000163528
olfcg4
olfactory receptor C family, g4
chr15_-_762319 0.14 ENSDART00000154306
ENSDART00000157492
si:dkey-7i4.16
znf1011
si:dkey-7i4.16
zinc finger protein 1011
chr17_-_15611744 0.14 ENSDART00000010496
fhl5
four and a half LIM domains 5
chr6_-_49159207 0.14 ENSDART00000041942
tspan2a
tetraspanin 2a
chr22_+_2247645 0.14 ENSDART00000143366
ENSDART00000147852
si:dkey-4c15.8
si:dkey-4c15.8
chr16_+_49005321 0.13 ENSDART00000160919
CABZ01068499.1

chr5_+_37890521 0.12 ENSDART00000140207
tmprss4b
transmembrane protease, serine 4b
chr18_+_31410652 0.12 ENSDART00000098504
def8
differentially expressed in FDCP 8 homolog (mouse)
chr13_-_18195942 0.12 ENSDART00000079902
slc25a16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr4_-_25858620 0.12 ENSDART00000128968
nr2c1
nuclear receptor subfamily 2, group C, member 1
chr15_-_25527580 0.12 ENSDART00000167005
ENSDART00000157498
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr5_-_66749535 0.12 ENSDART00000132183
kat5b
K(lysine) acetyltransferase 5b
chr14_+_45883687 0.12 ENSDART00000114790
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr10_-_39198942 0.12 ENSDART00000077619
b3gat1b
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b
chr1_+_23408622 0.12 ENSDART00000140706
chrna9
cholinergic receptor, nicotinic, alpha 9
chr21_+_6197223 0.12 ENSDART00000147716
si:dkey-93m18.3
si:dkey-93m18.3
chr20_-_29471577 0.12 ENSDART00000043382
grem1a
gremlin 1a, DAN family BMP antagonist
chr17_-_2811992 0.12 ENSDART00000067543
gpr65
G protein-coupled receptor 65
chr5_+_25304499 0.12 ENSDART00000163425
carnmt1
carnosine N-methyltransferase 1
chr17_+_25331576 0.11 ENSDART00000157309
tmem54a
transmembrane protein 54a
chr9_-_5263947 0.11 ENSDART00000088342
cytip
cytohesin 1 interacting protein
chr17_+_28882977 0.11 ENSDART00000153937
prkd1
protein kinase D1
chr20_-_9580446 0.11 ENSDART00000014168
zfp36l1b
zinc finger protein 36, C3H type-like 1b
chr16_-_44709832 0.10 ENSDART00000156784
si:ch211-151m7.6
si:ch211-151m7.6
chr2_-_32366989 0.10 ENSDART00000136758
ubtfl
upstream binding transcription factor, like
chr11_+_40812590 0.10 ENSDART00000186690
errfi1a
ERBB receptor feedback inhibitor 1a
chr13_+_45772924 0.10 ENSDART00000146964
si:ch211-62a1.3
si:ch211-62a1.3
chr14_-_736575 0.10 ENSDART00000168611
tlr1
toll-like receptor 1
chr1_-_55888970 0.10 ENSDART00000064194
asf1bb
anti-silencing function 1Bb histone chaperone
chr7_+_38808027 0.09 ENSDART00000052323
harbi1
harbinger transposase derived 1
chr23_+_7710447 0.09 ENSDART00000168199
kif3b
kinesin family member 3B
chr7_+_24006875 0.09 ENSDART00000033755
homezb
homeobox and leucine zipper encoding b
chr21_-_21828261 0.09 ENSDART00000151181
defbl2
defensin, beta-like 2
chr18_+_16133595 0.09 ENSDART00000080423
ctsd
cathepsin D
chr9_+_41156818 0.09 ENSDART00000105764
ENSDART00000147052
stat4
signal transducer and activator of transcription 4
chr3_+_37707432 0.09 ENSDART00000151236
map3k14a
mitogen-activated protein kinase kinase kinase 14a
chr2_+_13907452 0.09 ENSDART00000169724
ENSDART00000190691
zgc:66475
zgc:66475
chr12_+_19348538 0.09 ENSDART00000066388
tomm22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chr21_-_42055872 0.09 ENSDART00000144767
gabra1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr21_+_35289469 0.09 ENSDART00000155140
il12bb
interleukin 12B, b
chr22_+_2198246 0.09 ENSDART00000165168
ENSDART00000157485
ENSDART00000168713
znf1157
znf1166
zinc finger protein 1157
zinc finger protein 1166
chr20_+_5132138 0.08 ENSDART00000081351
ENSDART00000157685
cyp46a1.1
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1
chr25_+_22643954 0.08 ENSDART00000182843
ENSDART00000121791
ush1c
Usher syndrome 1C
chr4_-_25859305 0.08 ENSDART00000159528
nr2c1
nuclear receptor subfamily 2, group C, member 1
chr16_+_30002605 0.08 ENSDART00000160555
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr1_+_27713380 0.08 ENSDART00000169584
si:dkey-29d5.1
si:dkey-29d5.1
chr9_-_54304684 0.08 ENSDART00000109512
il13
interleukin 13
chr25_-_27564590 0.08 ENSDART00000073508
hyal4
hyaluronoglucosaminidase 4
chr1_+_52735484 0.08 ENSDART00000182076
CABZ01021532.1

chr19_-_46018152 0.08 ENSDART00000159206
krit1
KRIT1, ankyrin repeat containing
chr3_+_23731109 0.08 ENSDART00000131410
hoxb3a
homeobox B3a
chr11_+_45286911 0.07 ENSDART00000181763
pycr1b
pyrroline-5-carboxylate reductase 1b
chr15_-_39955785 0.07 ENSDART00000154556
msh5
mutS homolog 5
chr7_-_36358735 0.07 ENSDART00000188392
fto
fat mass and obesity associated
chr19_+_27342479 0.07 ENSDART00000184687
ddx39b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr18_+_12058403 0.07 ENSDART00000140854
ENSDART00000193632
ENSDART00000190519
ENSDART00000190685
ENSDART00000112671
bicd1a
bicaudal D homolog 1a
chr25_+_1335530 0.07 ENSDART00000090803
fem1b
fem-1 homolog b (C. elegans)
chr24_-_7587401 0.07 ENSDART00000093163
galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr24_+_13017586 0.06 ENSDART00000142457
stau2
staufen double-stranded RNA binding protein 2
chr24_-_20016817 0.06 ENSDART00000082201
ENSDART00000189448
slc22a13b
solute carrier family 22 member 13b
chr1_+_34701144 0.06 ENSDART00000150038
gtf2f2a
general transcription factor IIF, polypeptide 2a
chr18_-_19350792 0.06 ENSDART00000147902
megf11
multiple EGF-like-domains 11
chr16_+_1802307 0.06 ENSDART00000180026
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr22_-_21845685 0.06 ENSDART00000105564
aes
amino-terminal enhancer of split
chr3_-_22214029 0.06 ENSDART00000154818
maptb
microtubule-associated protein tau b
chr23_+_45027263 0.06 ENSDART00000058364
hmgb2b
high mobility group box 2b
chr22_+_9751117 0.06 ENSDART00000121827
BX664625.1

chr11_+_1867613 0.06 ENSDART00000065470
rbms2a
RNA binding motif, single stranded interacting protein 2a
chr7_+_29177191 0.06 ENSDART00000008096
aph1b
APH1B gamma secretase subunit
chr3_+_13850163 0.06 ENSDART00000164872
ilf3b
interleukin enhancer binding factor 3b
chr3_+_3139240 0.06 ENSDART00000105014
si:dkey-30g5.1
si:dkey-30g5.1
chr12_+_2446837 0.05 ENSDART00000112032
ARHGAP22
si:dkey-191m6.4
chr24_-_12981423 0.05 ENSDART00000133166
ENSDART00000131370
ENSDART00000002992
dcaf11
ddb1 and cul4 associated factor 11
chr4_+_11458078 0.05 ENSDART00000037600
ankrd16
ankyrin repeat domain 16
chr2_+_1881334 0.05 ENSDART00000161420
adgrl2b.1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr17_+_24722646 0.05 ENSDART00000138356
mtfr1l
mitochondrial fission regulator 1-like
chr7_-_44970682 0.05 ENSDART00000144591
fam96b
family with sequence similarity 96, member B
chr8_-_37461835 0.05 ENSDART00000013446
eif2d
eukaryotic translation initiation factor 2D
chr15_-_669476 0.05 ENSDART00000153687
ENSDART00000030603
si:ch211-210b2.2
si:ch211-210b2.2
chr7_-_38807819 0.05 ENSDART00000132772
ENSDART00000052324
atg13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr19_-_20777351 0.05 ENSDART00000019206
ngly1
N-glycanase 1
chr8_-_21142550 0.04 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr5_-_39736383 0.04 ENSDART00000127123
rasgef1ba
RasGEF domain family, member 1Ba
chr4_+_76426308 0.04 ENSDART00000180424
ENSDART00000159789
FP074874.1
zgc:172128

zgc:172128
chr5_-_30079434 0.04 ENSDART00000133981
bco2a
beta-carotene oxygenase 2a
chr3_+_18840810 0.04 ENSDART00000181137
ENSDART00000128626
ENSDART00000133332
tmem104
transmembrane protein 104
chr14_-_8625845 0.04 ENSDART00000054760
zgc:162144
zgc:162144
chr18_+_33322515 0.04 ENSDART00000136603
v2ra18
vomeronasal 2 receptor, a18
chr20_-_51656512 0.04 ENSDART00000129965
LO018154.1

chr10_-_5821584 0.04 ENSDART00000166388
il6st
interleukin 6 signal transducer
chr15_-_31514818 0.04 ENSDART00000153978
hmgb1b
high mobility group box 1b
chr9_+_38292947 0.04 ENSDART00000146663
tfcp2l1
transcription factor CP2-like 1
chr19_+_390298 0.03 ENSDART00000136361
sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr19_+_35002479 0.03 ENSDART00000103266
wdyhv1
WDYHV motif containing 1
chr1_+_31658011 0.03 ENSDART00000192203
poll
polymerase (DNA directed), lambda
chr4_-_73266929 0.03 ENSDART00000158194
wu:fc30c06
wu:fc30c06
chr14_-_33585809 0.03 ENSDART00000023540
sash3
SAM and SH3 domain containing 3
chr12_-_43428542 0.03 ENSDART00000192266
ptprea
protein tyrosine phosphatase, receptor type, E, a
chr15_+_34934568 0.03 ENSDART00000165210
zgc:66024
zgc:66024
chr7_-_67317119 0.03 ENSDART00000183915
psmd7
proteasome 26S subunit, non-ATPase 7
chr18_+_19842569 0.03 ENSDART00000147470
iqch
IQ motif containing H
chr1_+_31657842 0.03 ENSDART00000057880
poll
polymerase (DNA directed), lambda
chr17_+_41081512 0.03 ENSDART00000056742
babam2
BRISC and BRCA1 A complex member 2
chr4_-_13902188 0.03 ENSDART00000032805
gxylt1b
glucoside xylosyltransferase 1b
chr18_-_17724295 0.03 ENSDART00000121553
fam192a
family with sequence similarity 192, member A
chr2_-_9607879 0.03 ENSDART00000056899
txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr14_-_17576391 0.02 ENSDART00000161355
ENSDART00000168959
rnf4
ring finger protein 4
chr4_-_5538752 0.02 ENSDART00000180219
BX324164.5

chr11_+_2398843 0.02 ENSDART00000126761
pip4k2cb
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b
chr13_-_16257848 0.02 ENSDART00000079745
zgc:110045
zgc:110045
chr8_-_28357177 0.02 ENSDART00000182319
KLHL12 (1 of many)
kelch like family member 12
chr11_-_27702778 0.02 ENSDART00000045942
ENSDART00000125352
phf2
PHD finger protein 2
chr18_+_44673990 0.02 ENSDART00000018625
napab
N-ethylmaleimide-sensitive factor attachment protein, alpha b
chr2_-_3611960 0.01 ENSDART00000184579
pter
phosphotriesterase related
chr6_+_11026866 0.01 ENSDART00000189619
abcc6a
ATP-binding cassette, sub-family C (CFTR/MRP), member 6a
chr2_+_23039041 0.01 ENSDART00000056921
csnk1g2a
casein kinase 1, gamma 2a
chr22_+_1431743 0.01 ENSDART00000182871
BX322657.2
Danio rerio si:dkeyp-53d3.6 (si:dkeyp-53d3.6), mRNA.
chr20_-_37287107 0.01 ENSDART00000076309
nmbr
neuromedin B receptor
chr8_+_10001805 0.00 ENSDART00000132894
si:dkey-8e10.2
si:dkey-8e10.2
chr18_-_41164277 0.00 ENSDART00000187766
ENSDART00000185375
CABZ01005876.1

chr6_-_16717878 0.00 ENSDART00000153552
nomo
nodal modulator

Network of associatons between targets according to the STRING database.

First level regulatory network of six6a+six6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.1 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.9 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.2 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.0 0.1 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.0 0.3 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.0 GO:0010359 regulation of anion channel activity(GO:0010359)
0.0 0.2 GO:0072088 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.1 GO:0043584 nose development(GO:0043584)
0.0 0.4 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 1.3 GO:0002088 lens development in camera-type eye(GO:0002088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0070449 elongin complex(GO:0070449)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.0 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.5 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0043679 axon terminus(GO:0043679)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.4 GO:1903136 cuprous ion binding(GO:1903136)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.2 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.0 0.5 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.5 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 1.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.1 GO:1990931 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.1 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism