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PRJEB1986: zebrafish developmental stages transcriptome

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Results for sox12

Z-value: 0.77

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Transcription factors associated with sox12

Gene Symbol Gene ID Gene Info
sox12
ENSDARG00000025847 SRY-box transcription factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox12dr11_v1_chr11_-_24191928_24191928-0.302.1e-01Click!

Activity profile of sox12 motif

Sorted Z-values of sox12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_41922114 3.43 ENSDART00000138280
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr9_+_15893093 1.79 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
si:dkey-14o1.20
chr8_-_16697615 1.65 ENSDART00000187929
rpe65b
retinal pigment epithelium-specific protein 65b
chr2_-_31833347 1.56 ENSDART00000109460
nol7
nucleolar protein 7
chr16_-_9897613 1.53 ENSDART00000104058
ncalda
neurocalcin delta a
chr7_-_24995631 1.51 ENSDART00000173955
ENSDART00000173791
rcor2
REST corepressor 2
chr11_+_6115621 1.48 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr4_-_2945306 1.48 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr8_-_16697912 1.33 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr22_+_21618121 1.31 ENSDART00000133939
tle2a
transducin like enhancer of split 2a
chr7_+_44713135 1.26 ENSDART00000170721
si:dkey-56m19.5
si:dkey-56m19.5
chr6_-_55297274 1.17 ENSDART00000184283
ube2c
ubiquitin-conjugating enzyme E2C
chr17_+_7595356 1.16 ENSDART00000130625
si:dkeyp-110a12.4
si:dkeyp-110a12.4
chr17_+_43595692 1.13 ENSDART00000156271
cfap99
cilia and flagella associated protein 99
chr20_+_4221978 1.11 ENSDART00000171898
ipcef1
interaction protein for cytohesin exchange factors 1
chr7_-_38861741 1.10 ENSDART00000173629
ENSDART00000037361
ENSDART00000173953
phf21aa
PHD finger protein 21Aa
chr5_-_32363372 1.10 ENSDART00000098045
gas1b
growth arrest-specific 1b
chr5_+_26221011 1.09 ENSDART00000007587
gtf2h2
general transcription factor IIH, polypeptide 2
chr15_+_26933196 1.09 ENSDART00000023842
ppm1da
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr6_+_13333133 1.09 ENSDART00000038505
rprmb
reprimo, TP53 dependent G2 arrest mediator candidate b
chr5_-_24231139 1.07 ENSDART00000143492
senp3a
SUMO1/sentrin/SMT3 specific peptidase 3a
chr1_+_29798140 1.06 ENSDART00000019743
tm9sf2
transmembrane 9 superfamily member 2
chr7_+_24729558 1.05 ENSDART00000111542
ENSDART00000170100
shroom4
shroom family member 4
chr11_+_37768298 1.01 ENSDART00000166886
sox13
SRY (sex determining region Y)-box 13
chr11_+_24820542 1.01 ENSDART00000135443
kdm5ba
lysine (K)-specific demethylase 5Ba
chr4_+_15954293 1.00 ENSDART00000132695
si:dkey-117n7.4
si:dkey-117n7.4
chr11_+_6116096 1.00 ENSDART00000159680
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr3_-_1146497 0.99 ENSDART00000149061
si:ch73-211l13.2
si:ch73-211l13.2
chr16_-_16237844 0.98 ENSDART00000168747
ENSDART00000111912
rbm12b
RNA binding motif protein 12B
chr6_+_46406565 0.94 ENSDART00000168440
ENSDART00000131203
ENSDART00000138567
ENSDART00000132845
pbrm1l
polybromo 1, like
chr4_+_11723852 0.94 ENSDART00000028820
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr2_-_24069331 0.93 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr4_+_9030609 0.92 ENSDART00000154399
aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr8_-_19313510 0.89 ENSDART00000164780
ENSDART00000137133
rgl1
ral guanine nucleotide dissociation stimulator-like 1
chr16_+_32082547 0.88 ENSDART00000190122
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr14_+_21686207 0.87 ENSDART00000034438
ran
RAN, member RAS oncogene family
chr20_-_23876291 0.87 ENSDART00000043316
katna1
katanin p60 (ATPase containing) subunit A 1
chr10_+_3153973 0.87 ENSDART00000183223
hic2
hypermethylated in cancer 2
chr23_+_9268083 0.85 ENSDART00000055054
acss2
acyl-CoA synthetase short chain family member 2
chr1_+_594736 0.84 ENSDART00000166731
jam2a
junctional adhesion molecule 2a
chr8_+_42998944 0.84 ENSDART00000048819
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr15_+_37545855 0.83 ENSDART00000099456
psenen
presenilin enhancer gamma secretase subunit
chr6_-_37460178 0.80 ENSDART00000153500
si:dkey-66a8.7
si:dkey-66a8.7
chr16_+_11242443 0.80 ENSDART00000024935
gsk3ab
glycogen synthase kinase 3 alpha b
chr3_-_35865040 0.79 ENSDART00000102952
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr15_+_31911989 0.78 ENSDART00000111472
brca2
breast cancer 2, early onset
chr9_-_1970071 0.78 ENSDART00000080608
hoxd10a
homeobox D10a
chr6_+_28877306 0.77 ENSDART00000065137
ENSDART00000123189
ENSDART00000065135
ENSDART00000181512
ENSDART00000130799
tp63
tumor protein p63
chr17_-_25303486 0.77 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr14_-_44773864 0.76 ENSDART00000158386
si:dkey-109l4.3
si:dkey-109l4.3
chr22_-_784110 0.73 ENSDART00000061775
rbbp5
retinoblastoma binding protein 5
chr22_-_9861531 0.73 ENSDART00000193197
si:dkey-253d23.2
si:dkey-253d23.2
chr16_-_9897769 0.72 ENSDART00000187044
ncalda
neurocalcin delta a
chr3_+_61523035 0.71 ENSDART00000106530
znf1004
zinc finger protein 1004
chr13_+_9559461 0.71 ENSDART00000047740
wdr32
WD repeat domain 32
chr18_+_22138924 0.69 ENSDART00000183961
ripor1
RHO family interacting cell polarization regulator 1
chr3_+_40284598 0.67 ENSDART00000009411
bud31
BUD31 homolog (S. cerevisiae)
chr7_+_29115890 0.67 ENSDART00000052345
tradd
tnfrsf1a-associated via death domain
chr11_-_21267486 0.66 ENSDART00000128681
DYRK3
zgc:172180
chr15_+_35691783 0.65 ENSDART00000183994
CT573366.1

chr10_-_1718395 0.65 ENSDART00000137620
si:ch73-46j18.5
si:ch73-46j18.5
chr16_-_41762983 0.63 ENSDART00000192936
si:dkey-199f5.8
si:dkey-199f5.8
chr7_+_25003313 0.63 ENSDART00000131935
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr25_-_31171948 0.63 ENSDART00000184275
FQ976913.1

chr22_-_37349967 0.62 ENSDART00000104493
sox2
SRY (sex determining region Y)-box 2
chr17_-_21057617 0.62 ENSDART00000148095
ENSDART00000048853
ube2d1a
ubiquitin-conjugating enzyme E2D 1a
chr1_+_17593392 0.62 ENSDART00000078889
helt
helt bHLH transcription factor
chr15_-_1484795 0.61 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr3_-_16110351 0.60 ENSDART00000064838
lasp1
LIM and SH3 protein 1
chr22_-_9860792 0.60 ENSDART00000155908
si:dkey-253d23.2
si:dkey-253d23.2
chr1_-_52790724 0.59 ENSDART00000139577
ENSDART00000100937
patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr7_-_26924903 0.59 ENSDART00000124363
alx4a
ALX homeobox 4a
chr12_+_4160804 0.58 ENSDART00000152515
itgam
integrin, alpha M (complement component 3 receptor 3 subunit)
chr10_+_10972795 0.57 ENSDART00000127331
cdc37l1
cell division cycle 37-like 1
chr7_-_28565230 0.57 ENSDART00000028887
tmem9b
TMEM9 domain family, member B
chr24_-_15263142 0.56 ENSDART00000183176
ENSDART00000006930
rttn
rotatin
chr1_+_33668236 0.54 ENSDART00000122316
ENSDART00000102184
arl13b
ADP-ribosylation factor-like 13b
chr12_+_10163585 0.53 ENSDART00000106191
psmc5
proteasome 26S subunit, ATPase 5
chr1_+_40613297 0.53 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr1_-_26071535 0.52 ENSDART00000185187
pdcd4a
programmed cell death 4a
chr10_+_5268054 0.51 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr16_+_25343934 0.51 ENSDART00000109710
zfat
zinc finger and AT hook domain containing
chr9_-_31278048 0.51 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr1_-_43987873 0.50 ENSDART00000108821
CR385050.1

chr14_-_33297287 0.50 ENSDART00000045555
ENSDART00000138294
ENSDART00000075056
rab41
RAB41, member RAS oncogene family
chr3_+_32689707 0.50 ENSDART00000029262
si:dkey-16l2.17
si:dkey-16l2.17
chr5_+_58455488 0.50 ENSDART00000038602
ENSDART00000127958
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr20_+_4222357 0.49 ENSDART00000188331
ipcef1
interaction protein for cytohesin exchange factors 1
chr13_+_29510023 0.48 ENSDART00000187398
chst3a
carbohydrate (chondroitin 6) sulfotransferase 3a
chr15_-_35930070 0.47 ENSDART00000076229
irs1
insulin receptor substrate 1
chr6_-_37459759 0.47 ENSDART00000190666
si:dkey-66a8.7
si:dkey-66a8.7
chr17_-_23412705 0.47 ENSDART00000126995
si:ch211-149k12.3
si:ch211-149k12.3
chr8_-_16712111 0.47 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
rpe65c
retinal pigment epithelium-specific protein 65c
chr20_+_35445462 0.45 ENSDART00000124497
tdrd6
tudor domain containing 6
chr2_-_7696503 0.44 ENSDART00000169709
CABZ01055306.1

chr14_+_48960078 0.43 ENSDART00000165514
mif
macrophage migration inhibitory factor
chr19_-_4010263 0.43 ENSDART00000159605
ENSDART00000165541
map7d1b
MAP7 domain containing 1b
chr25_+_10485103 0.43 ENSDART00000104576
psmd13
proteasome 26S subunit, non-ATPase 13
chr8_+_48480529 0.43 ENSDART00000186631
PRDM16
si:ch211-263k4.2
chr1_+_47331644 0.43 ENSDART00000053284
bcl9
B cell CLL/lymphoma 9
chr24_+_20920563 0.42 ENSDART00000037224
cst14a.2
cystatin 14a, tandem duplicate 2
chr20_-_33976305 0.41 ENSDART00000111022
sele
selectin E
chr3_-_16110100 0.41 ENSDART00000051807
lasp1
LIM and SH3 protein 1
chr15_+_37546391 0.40 ENSDART00000186625
psenen
presenilin enhancer gamma secretase subunit
chr12_-_17863467 0.39 ENSDART00000042006
baiap2l1a
BAI1-associated protein 2-like 1a
chr22_-_16494406 0.39 ENSDART00000062727
stx6
syntaxin 6
chr23_+_36083529 0.38 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr15_-_28587147 0.37 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr11_+_7580079 0.37 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adgrl2a
adhesion G protein-coupled receptor L2a
chr10_-_25591194 0.37 ENSDART00000131640
tiam1a
T cell lymphoma invasion and metastasis 1a
chr19_+_22062202 0.35 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr23_+_30707837 0.34 ENSDART00000016096
dnajc11a
DnaJ (Hsp40) homolog, subfamily C, member 11a
chr19_-_42556086 0.34 ENSDART00000051731
si:dkey-267n13.1
si:dkey-267n13.1
chr9_-_16140860 0.32 ENSDART00000142974
myo1b
myosin IB
chr3_-_33175583 0.31 ENSDART00000126022
rarab
retinoic acid receptor, alpha b
chr9_+_24920677 0.31 ENSDART00000037025
slc39a10
solute carrier family 39 (zinc transporter), member 10
chr8_+_30600386 0.30 ENSDART00000164976
specc1la
sperm antigen with calponin homology and coiled-coil domains 1-like a
chr1_+_26071869 0.30 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr17_+_7534365 0.30 ENSDART00000157123
shprh
SNF2 histone linker PHD RING helicase
chr17_+_30843881 0.29 ENSDART00000149600
ENSDART00000148547
tpp1
tripeptidyl peptidase I
chr7_-_30217000 0.29 ENSDART00000173646
znf710b
zinc finger protein 710b
chr13_+_35765317 0.26 ENSDART00000100156
ENSDART00000167650
agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr17_-_15229787 0.26 ENSDART00000039165
styx
serine/threonine/tyrosine interacting protein
chr14_-_2004291 0.26 ENSDART00000114039
pcdh2g5
protocadherin 2 gamma 5
chr25_+_28825657 0.25 ENSDART00000153625
nfybb
nuclear transcription factor Y, beta b
chr25_+_22017182 0.24 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr7_-_735118 0.24 ENSDART00000126424
MAP3K11
si:cabz01078036.1
chr6_+_11829867 0.24 ENSDART00000151044
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr20_+_1385674 0.24 ENSDART00000145981
mmachc
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr12_-_22400999 0.23 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr19_+_8481802 0.23 ENSDART00000050217
efna1a
ephrin-A1a
chr15_+_32419303 0.23 ENSDART00000162663
si:dkey-285b23.3
si:dkey-285b23.3
chr11_+_31864921 0.22 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr11_-_16394971 0.22 ENSDART00000180981
ENSDART00000179925
lrig1
leucine-rich repeats and immunoglobulin-like domains 1
chr2_-_43130812 0.22 ENSDART00000039079
ENSDART00000056162
ftr13
finTRIM family, member 13
chr4_-_14531687 0.19 ENSDART00000182093
ENSDART00000159447
plxnb2a
plexin b2a
chr19_+_20708460 0.19 ENSDART00000034124
rab5aa
RAB5A, member RAS oncogene family, a
chr6_+_20647155 0.19 ENSDART00000193477
slc19a1
solute carrier family 19 (folate transporter), member 1
chr18_-_14337450 0.18 ENSDART00000061435
hsbp1b
heat shock factor binding protein 1b
chr24_-_41267184 0.18 ENSDART00000063504
xylb
xylulokinase homolog (H. influenzae)
chr9_-_53817143 0.18 ENSDART00000148764
ENSDART00000075537
ednrbb
endothelin receptor type Bb
chr23_-_36449111 0.18 ENSDART00000110478
zgc:174906
zgc:174906
chr8_-_2153147 0.17 ENSDART00000124093
si:dkeyp-117b11.1
si:dkeyp-117b11.1
chr12_+_34763795 0.17 ENSDART00000153097
slc38a10
solute carrier family 38, member 10
chr14_+_26229056 0.16 ENSDART00000179045
LO018208.1

chr15_-_16946124 0.16 ENSDART00000154923
hip1
huntingtin interacting protein 1
chr6_+_33897624 0.16 ENSDART00000166706
ccdc17
coiled-coil domain containing 17
chr13_-_33317323 0.15 ENSDART00000110295
ENSDART00000144848
ENSDART00000136701
tmem234
transmembrane protein 234
chr8_-_13419049 0.15 ENSDART00000133656
pimr101
Pim proto-oncogene, serine/threonine kinase, related 101
chr10_+_8554929 0.15 ENSDART00000190849
tbc1d10ab
TBC1 domain family, member 10Ab
chr8_+_46217861 0.15 ENSDART00000038790
angptl7
angiopoietin-like 7
chr17_+_7534180 0.15 ENSDART00000187512
shprh
SNF2 histone linker PHD RING helicase
chr8_-_13471916 0.15 ENSDART00000146558
pimr105
Pim proto-oncogene, serine/threonine kinase, related 105
chr10_+_9550419 0.14 ENSDART00000064977
si:ch211-243g18.2
si:ch211-243g18.2
chr8_-_38201415 0.13 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr16_-_28091597 0.13 ENSDART00000166595
CR626941.1

chr8_+_54135642 0.12 ENSDART00000170712
brpf1
bromodomain and PHD finger containing, 1
chr5_+_3891485 0.11 ENSDART00000129329
ENSDART00000091711
rpain
RPA interacting protein
chr8_-_52229462 0.11 ENSDART00000185949
ENSDART00000051825
tcf7l1b
transcription factor 7 like 1b
chr5_-_37875636 0.11 ENSDART00000184674
arhgap35b
Rho GTPase activating protein 35b
chr23_-_29824146 0.10 ENSDART00000020616
zgc:194189
zgc:194189
chr24_+_36392040 0.09 ENSDART00000136057
arf2b
ADP-ribosylation factor 2b
chr16_+_32082359 0.09 ENSDART00000140794
ENSDART00000137029
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr5_-_24124118 0.09 ENSDART00000051550
capga
capping protein (actin filament), gelsolin-like a
chr3_-_60856157 0.08 ENSDART00000053502
CABZ01087513.1

chr14_-_48033073 0.08 ENSDART00000193115
ENSDART00000169300
ENSDART00000188036
ENSDART00000183432
ENSDART00000180973
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr7_+_22585447 0.08 ENSDART00000149144
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr8_-_24252933 0.07 ENSDART00000057624
zgc:110353
zgc:110353
chr21_+_30549512 0.07 ENSDART00000132831
rab38c
RAB38c, member of RAS oncogene family
chr3_-_8144421 0.06 ENSDART00000170603
si:ch211-51i16.3
si:ch211-51i16.3
chr17_-_49443247 0.05 ENSDART00000059245
cga
glycoprotein hormones, alpha polypeptide
chr9_+_30211038 0.05 ENSDART00000190847
senp7a
SUMO1/sentrin specific peptidase 7a
chr20_-_14114078 0.05 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr18_+_8912710 0.05 ENSDART00000142866
tmem243a
transmembrane protein 243, mitochondrial a
chr17_-_49443399 0.04 ENSDART00000155293
cga
glycoprotein hormones, alpha polypeptide
chr10_+_43189325 0.04 ENSDART00000185584
vcanb
versican b
chr17_-_12712776 0.03 ENSDART00000064511
il17a/f1
interleukin 17a/f1
chr3_-_34027178 0.02 ENSDART00000170201
ENSDART00000151408
ighv1-4
ighv14-1
immunoglobulin heavy variable 1-4
immunoglobulin heavy variable 14-1
chr2_-_16217344 0.02 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr9_+_537297 0.02 ENSDART00000165149
CU984600.3

chr6_-_41135215 0.02 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr8_-_43456025 0.00 ENSDART00000001092
ENSDART00000140618
ncor2
nuclear receptor corepressor 2
chr16_+_12812472 0.00 ENSDART00000008535
u2af2a
U2 small nuclear RNA auxiliary factor 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of sox12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0016109 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.6 3.4 GO:0055016 hypochord development(GO:0055016)
0.3 0.9 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 0.9 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.2 0.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.2 0.5 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 1.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.9 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 1.2 GO:0034205 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.9 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.8 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 0.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.5 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.6 GO:0021982 pineal gland development(GO:0021982)
0.1 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.5 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 1.1 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.2 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 0.2 GO:0015893 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 0.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.8 GO:0008585 sex determination(GO:0007530) female gonad development(GO:0008585)
0.1 0.3 GO:0043393 regulation of protein binding(GO:0043393)
0.0 0.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0030719 P granule organization(GO:0030719)
0.0 0.1 GO:0010893 positive regulation of steroid biosynthetic process(GO:0010893)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044) chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0003139 secondary heart field specification(GO:0003139)
0.0 1.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 1.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.5 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 1.3 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.6 GO:0050821 protein stabilization(GO:0050821)
0.0 0.6 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.2 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.4 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 3.6 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 1.1 GO:0000439 core TFIIH complex(GO:0000439)
0.2 1.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 0.5 GO:0033391 chromatoid body(GO:0033391)
0.1 0.9 GO:0016586 RSC complex(GO:0016586)
0.1 1.0 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 3.4 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 2.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 0.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 1.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0005921 gap junction(GO:0005921)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.9 3.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 0.9 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 0.9 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 0.5 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 0.6 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.1 0.5 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.1 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.2 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 1.0 GO:0017069 snRNA binding(GO:0017069)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 2.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 1.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.7 GO:0003682 chromatin binding(GO:0003682)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.1 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.1 0.9 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.0 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA