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PRJEB1986: zebrafish developmental stages transcriptome

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Results for sox4a+sox4b

Z-value: 0.57

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Transcription factors associated with sox4a+sox4b

Gene Symbol Gene ID Gene Info
sox4a
ENSDARG00000004588 SRY-box transcription factor 4a
sox4b
ENSDARG00000098834 SRY-box transcription factor 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox4adr11_v1_chr19_-_28789404_28789409-0.522.3e-02Click!
sox4bdr11_v1_chr16_+_68069_68124-0.445.7e-02Click!

Activity profile of sox4a+sox4b motif

Sorted Z-values of sox4a+sox4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_3758637 1.32 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
hmga1a
high mobility group AT-hook 1a
chr9_+_15893093 1.16 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
si:dkey-14o1.20
chr23_-_3759345 0.92 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
hmga1a
high mobility group AT-hook 1a
chr6_+_46406565 0.81 ENSDART00000168440
ENSDART00000131203
ENSDART00000138567
ENSDART00000132845
pbrm1l
polybromo 1, like
chr19_-_46037835 0.81 ENSDART00000163815
nup153
nucleoporin 153
chr8_+_17869225 0.77 ENSDART00000080079
slc44a5b
solute carrier family 44, member 5b
chr1_+_17376922 0.76 ENSDART00000145068
fat1a
FAT atypical cadherin 1a
chr5_+_43870389 0.72 ENSDART00000141002
zgc:112966
zgc:112966
chr19_-_18152407 0.71 ENSDART00000193264
ENSDART00000016135
nfe2l3
nuclear factor, erythroid 2-like 3
chr5_+_44846434 0.71 ENSDART00000145299
ENSDART00000136521
kank1a
KN motif and ankyrin repeat domains 1a
chr2_-_24069331 0.68 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr13_+_48358467 0.63 ENSDART00000171080
ENSDART00000162531
msh6
mutS homolog 6 (E. coli)
chr8_-_16697912 0.62 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr3_-_27646070 0.61 ENSDART00000122031
ENSDART00000151027
si:ch211-157c3.4
si:ch211-157c3.4
chr16_-_41762983 0.60 ENSDART00000192936
si:dkey-199f5.8
si:dkey-199f5.8
chr7_-_55454406 0.57 ENSDART00000108646
piezo1
piezo-type mechanosensitive ion channel component 1
chr8_+_29636431 0.57 ENSDART00000133047
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr14_-_2004291 0.56 ENSDART00000114039
pcdh2g5
protocadherin 2 gamma 5
chr4_+_15954293 0.56 ENSDART00000132695
si:dkey-117n7.4
si:dkey-117n7.4
chr20_-_33790003 0.55 ENSDART00000020183
fam102bb
family with sequence similarity 102, member B, b
chr16_-_33104944 0.54 ENSDART00000151943
pnrc2
proline-rich nuclear receptor coactivator 2
chr21_-_5077715 0.53 ENSDART00000081954
haus1
HAUS augmin-like complex, subunit 1
chr7_-_24995631 0.53 ENSDART00000173955
ENSDART00000173791
rcor2
REST corepressor 2
chr21_-_37027252 0.52 ENSDART00000076483
zgc:77151
zgc:77151
chr24_+_17142881 0.52 ENSDART00000177272
ENSDART00000192259
ENSDART00000191029
mllt10
MLLT10, histone lysine methyltransferase DOT1L cofactor
chr17_+_25849332 0.52 ENSDART00000191994
acss1
acyl-CoA synthetase short chain family member 1
chr7_-_57332915 0.52 ENSDART00000162653
BX470176.1

chr11_+_14057605 0.50 ENSDART00000166262
grin3bb
glutamate receptor, ionotropic, N-methyl-D-aspartate 3Bb
chr13_-_21650404 0.49 ENSDART00000078352
tspan14
tetraspanin 14
chr20_+_34770197 0.49 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr22_-_22301672 0.48 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr19_-_17774875 0.47 ENSDART00000151133
ENSDART00000130695
top2b
DNA topoisomerase II beta
chr10_-_36633882 0.47 ENSDART00000077161
ENSDART00000137688
rsf1b.1
rsf1b.1
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr16_+_35535375 0.47 ENSDART00000171675
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr11_+_3501669 0.47 ENSDART00000160808
pusl1
pseudouridylate synthase-like 1
chr10_-_25628555 0.46 ENSDART00000143978
tiam1a
T cell lymphoma invasion and metastasis 1a
chr11_+_6115621 0.46 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr6_+_17789481 0.46 ENSDART00000190768
CR376861.1

chr15_+_35691783 0.45 ENSDART00000183994
CT573366.1

chr5_-_12093618 0.45 ENSDART00000161542
lrrc74b
leucine rich repeat containing 74B
chr6_-_9282080 0.44 ENSDART00000159506
ccdc14
coiled-coil domain containing 14
chr5_-_46505691 0.44 ENSDART00000111589
ENSDART00000122966
ENSDART00000166907
hapln1a
hyaluronan and proteoglycan link protein 1a
chr6_+_59832786 0.43 ENSDART00000154985
ENSDART00000102148
ddx3b
DEAD (Asp-Glu-Ala-Asp) box helicase 3b
chr17_+_24632440 0.42 ENSDART00000157092
map4k3b
mitogen-activated protein kinase kinase kinase kinase 3b
chr7_+_53879191 0.42 ENSDART00000164768
neo1a
neogenin 1a
chr9_-_32142311 0.42 ENSDART00000142768
ankrd44
ankyrin repeat domain 44
chr5_+_23045096 0.41 ENSDART00000171719
atrxl
alpha thalassemia/mental retardation syndrome X-linked, like
chr19_+_7424347 0.41 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr24_+_9696760 0.41 ENSDART00000140200
ENSDART00000187411
topbp1
DNA topoisomerase II binding protein 1
chr15_+_28368823 0.41 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr4_-_20511595 0.40 ENSDART00000185806
rassf8b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b
chr6_-_59505589 0.39 ENSDART00000170685
gli1
GLI family zinc finger 1
chr2_-_20574193 0.39 ENSDART00000190448
si:ch211-267e7.3
si:ch211-267e7.3
chr19_-_17208728 0.39 ENSDART00000151228
stmn1a
stathmin 1a
chr21_-_2310064 0.39 ENSDART00000169520
si:ch211-241b2.1
si:ch211-241b2.1
chr12_+_48340133 0.39 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr13_+_28732101 0.39 ENSDART00000015773
ldb1a
LIM domain binding 1a
chr23_+_36144487 0.38 ENSDART00000082473
hoxc3a
homeobox C3a
chr13_-_5257303 0.38 ENSDART00000110610
si:dkey-78p8.1
si:dkey-78p8.1
chr11_+_30296332 0.38 ENSDART00000192843
ugt1b7
UDP glucuronosyltransferase 1 family, polypeptide B7
chr17_+_7534180 0.38 ENSDART00000187512
shprh
SNF2 histone linker PHD RING helicase
chr22_-_10440688 0.38 ENSDART00000111962
nol8
nucleolar protein 8
chr19_-_7540821 0.38 ENSDART00000143958
lix1l
limb and CNS expressed 1 like
chr5_+_44846280 0.38 ENSDART00000084370
kank1a
KN motif and ankyrin repeat domains 1a
chr13_+_2894536 0.36 ENSDART00000183678
CABZ01087629.1

chr14_+_6962271 0.36 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr22_+_12161738 0.36 ENSDART00000168857
ccnt2b
cyclin T2b
chr17_+_7534365 0.35 ENSDART00000157123
shprh
SNF2 histone linker PHD RING helicase
chr3_+_60761811 0.35 ENSDART00000053482
tsen54
TSEN54 tRNA splicing endonuclease subunit
chr25_+_31323978 0.35 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr14_+_6963312 0.35 ENSDART00000150050
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr1_+_41609676 0.35 ENSDART00000183675
mogs
mannosyl-oligosaccharide glucosidase
chr14_-_44773864 0.35 ENSDART00000158386
si:dkey-109l4.3
si:dkey-109l4.3
chr12_+_2804505 0.34 ENSDART00000152193
mms19
MMS19 homolog, cytosolic iron-sulfur assembly component
chr21_-_9914745 0.34 ENSDART00000172124
arhgap24
Rho GTPase activating protein 24
chr17_-_4252221 0.34 ENSDART00000152020
gdf3
growth differentiation factor 3
chr4_+_48770245 0.34 ENSDART00000138053
znf1020
zinc finger protein 1020
chr9_-_695000 0.34 ENSDART00000181318
ENSDART00000115030
dip2a
disco-interacting protein 2 homolog A
chr3_-_25054002 0.34 ENSDART00000086768
ep300b
E1A binding protein p300 b
chr10_+_32058692 0.33 ENSDART00000062309
thap12a
THAP domain containing 12a
chr16_+_26732086 0.33 ENSDART00000138496
rad54b
RAD54 homolog B (S. cerevisiae)
chr5_-_22602979 0.33 ENSDART00000146287
nono
non-POU domain containing, octamer-binding
chr16_-_26731928 0.33 ENSDART00000135860
rnf41l
ring finger protein 41, like
chr16_-_33105677 0.32 ENSDART00000145055
pnrc2
proline-rich nuclear receptor coactivator 2
chr23_+_36122058 0.32 ENSDART00000184448
hoxc3a
homeobox C3a
chr10_-_2788668 0.32 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr6_+_12968101 0.32 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr11_+_807153 0.32 ENSDART00000173289
vgll4b
vestigial-like family member 4b
chr21_-_32781612 0.31 ENSDART00000031028
cnot6a
CCR4-NOT transcription complex, subunit 6a
chr19_-_20482261 0.31 ENSDART00000056205
satb1a
SATB homeobox 1a
chr7_-_24875421 0.31 ENSDART00000173920
adad2
adenosine deaminase domain containing 2
chr7_+_65876335 0.31 ENSDART00000150143
tead1b
TEA domain family member 1b
chr6_-_31224563 0.31 ENSDART00000104616
lepr
leptin receptor
chr21_-_2310355 0.31 ENSDART00000183326
si:ch211-241b2.1
si:ch211-241b2.1
chr22_-_7025393 0.30 ENSDART00000003422
smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr3_-_21348478 0.30 ENSDART00000114906
fam171a2a
family with sequence similarity 171, member A2a
chr6_-_12172424 0.30 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr5_-_22602780 0.30 ENSDART00000011699
nono
non-POU domain containing, octamer-binding
chr17_+_44030692 0.30 ENSDART00000049503
peli2
pellino E3 ubiquitin protein ligase family member 2
chr22_-_9861531 0.29 ENSDART00000193197
si:dkey-253d23.2
si:dkey-253d23.2
chr8_-_51340773 0.29 ENSDART00000060633
kansl3
KAT8 regulatory NSL complex subunit 3
chr23_+_25428513 0.29 ENSDART00000144554
fmnl3
formin-like 3
chr15_+_28368644 0.29 ENSDART00000168453
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr1_-_43987873 0.29 ENSDART00000108821
CR385050.1

chr12_-_20616160 0.28 ENSDART00000105362
snx11
sorting nexin 11
chr12_+_28856151 0.28 ENSDART00000152969
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr17_+_48164536 0.28 ENSDART00000161750
ENSDART00000156923
plekhd1
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
chr1_+_44173506 0.28 ENSDART00000170512
ctnnd1
catenin (cadherin-associated protein), delta 1
chr8_+_54135642 0.28 ENSDART00000170712
brpf1
bromodomain and PHD finger containing, 1
chr16_+_25342152 0.27 ENSDART00000156351
zfat
zinc finger and AT hook domain containing
chr19_+_43969363 0.26 ENSDART00000051712
gatad1
GATA zinc finger domain containing 1
chr25_-_35112466 0.26 ENSDART00000183481
CU302436.4

chr15_+_19458982 0.26 ENSDART00000132665
zgc:77784
zgc:77784
chr20_+_31269778 0.26 ENSDART00000133353
apobb.1
apolipoprotein Bb, tandem duplicate 1
chr21_-_2341937 0.26 ENSDART00000158459
zgc:193790
zgc:193790
chr22_-_9860792 0.26 ENSDART00000155908
si:dkey-253d23.2
si:dkey-253d23.2
chr13_+_5978809 0.26 ENSDART00000102563
ENSDART00000121598
phf10
PHD finger protein 10
chr4_+_9177997 0.25 ENSDART00000057254
ENSDART00000154614
nfyba
nuclear transcription factor Y, beta a
chr4_-_15003854 0.25 ENSDART00000134701
ENSDART00000002401
klhdc10
kelch domain containing 10
chr9_+_27329640 0.25 ENSDART00000111039
GTPBP8
si:rp71-84d19.3
chr2_-_52455525 0.25 ENSDART00000160768
ENSDART00000002241
chico
chico
chr17_-_5860222 0.25 ENSDART00000058894
si:ch73-340m8.2
si:ch73-340m8.2
chr10_+_29849497 0.25 ENSDART00000099994
ENSDART00000132212
hspa8
heat shock protein 8
chr17_-_45378473 0.25 ENSDART00000132969
znf106a
zinc finger protein 106a
chr14_-_1958994 0.25 ENSDART00000161783
pcdh2g5
protocadherin 2 gamma 5
chr1_+_29766725 0.24 ENSDART00000054064
zc3h13
zinc finger CCCH-type containing 13
chr4_+_9178913 0.24 ENSDART00000168558
nfyba
nuclear transcription factor Y, beta a
chr25_+_28776562 0.24 ENSDART00000109702
slc41a2a
solute carrier family 41 (magnesium transporter), member 2a
chr21_+_4540127 0.24 ENSDART00000043431
nup188
nucleoporin 188
chr4_-_178510 0.24 ENSDART00000169805
eps8
epidermal growth factor receptor pathway substrate 8
chr2_-_22966076 0.24 ENSDART00000143412
ENSDART00000146014
ENSDART00000183443
ENSDART00000191056
ENSDART00000183539
sap130b
Sin3A-associated protein b
chr11_+_24820542 0.24 ENSDART00000135443
kdm5ba
lysine (K)-specific demethylase 5Ba
chr9_+_12948511 0.24 ENSDART00000135797
si:dkey-230p4.1
si:dkey-230p4.1
chr20_-_16498991 0.24 ENSDART00000104137
ches1
checkpoint suppressor 1
chr1_-_8566567 0.24 ENSDART00000114613
ptcd1
pentatricopeptide repeat domain 1
chr16_+_25068576 0.23 ENSDART00000125838
im:7147486
im:7147486
chr21_+_26748141 0.23 ENSDART00000169025
pcxa
pyruvate carboxylase a
chr16_+_35535171 0.23 ENSDART00000167001
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr10_-_1827225 0.23 ENSDART00000058627
epb41l4a
erythrocyte membrane protein band 4.1 like 4A
chr13_+_39188737 0.23 ENSDART00000083641
fam135a
family with sequence similarity 135, member A
chr16_+_6750756 0.22 ENSDART00000149720
znf236
zinc finger protein 236
chr4_+_13953537 0.22 ENSDART00000133596
pphln1
periphilin 1
chr1_-_34335752 0.22 ENSDART00000140157
si:dkey-24h22.5
si:dkey-24h22.5
chr14_-_1955257 0.22 ENSDART00000193254
pcdh2g5
protocadherin 2 gamma 5
chr5_+_41477954 0.22 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr10_-_25591194 0.22 ENSDART00000131640
tiam1a
T cell lymphoma invasion and metastasis 1a
chr1_-_51720633 0.22 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr24_+_18714212 0.22 ENSDART00000171181
cspp1a
centrosome and spindle pole associated protein 1a
chr11_+_3959495 0.22 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr22_-_22337382 0.22 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr14_+_39258569 0.21 ENSDART00000103298
diaph2
diaphanous-related formin 2
chr19_+_40026959 0.21 ENSDART00000123647
sfpq
splicing factor proline/glutamine-rich
chr12_+_10115964 0.21 ENSDART00000152369
si:dkeyp-118b1.2
si:dkeyp-118b1.2
chr3_-_52661242 0.21 ENSDART00000138018
zgc:113210
zgc:113210
chr8_-_16712111 0.21 ENSDART00000184147
ENSDART00000180419
ENSDART00000076600
rpe65c
retinal pigment epithelium-specific protein 65c
chr1_+_14073891 0.21 ENSDART00000021693
ank2a
ankyrin 2a, neuronal
chr20_-_49681850 0.21 ENSDART00000025926
col12a1b
collagen, type XII, alpha 1b
chr3_-_29891218 0.21 ENSDART00000142118
slc25a39
solute carrier family 25, member 39
chr5_-_32383475 0.21 ENSDART00000141294
fbxw2
F-box and WD repeat domain containing 2
chr14_-_31151148 0.21 ENSDART00000026569
gpc4
glypican 4
chr2_-_57264262 0.21 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
mbd3a
methyl-CpG binding domain protein 3a
chr2_+_35733335 0.21 ENSDART00000113489
rasal2
RAS protein activator like 2
chr19_+_7636941 0.21 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr12_-_28848015 0.20 ENSDART00000153200
si:ch211-194k22.8
si:ch211-194k22.8
chr7_+_73827805 0.20 ENSDART00000109316
zgc:173587
zgc:173587
chr6_+_7322587 0.20 ENSDART00000065500
abcc4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr15_+_22435460 0.20 ENSDART00000031976
tmem136a
transmembrane protein 136a
chr1_+_44173245 0.20 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr10_+_29849977 0.20 ENSDART00000180242
hspa8
heat shock protein 8
chr7_+_20019125 0.20 ENSDART00000186391
bcl6b
B-cell CLL/lymphoma 6, member B
chr7_-_69636502 0.20 ENSDART00000126739
tspan5a
tetraspanin 5a
chr5_+_20823409 0.20 ENSDART00000093185
ENSDART00000142894
limk2
LIM domain kinase 2
chr8_+_4803906 0.19 ENSDART00000045533
tmem127
transmembrane protein 127
chr2_-_3038904 0.19 ENSDART00000186795
guk1a
guanylate kinase 1a
chr20_+_3277620 0.19 ENSDART00000067397
ENSDART00000135194
ndufaf7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr14_-_41272034 0.19 ENSDART00000191709
ENSDART00000074438
cenpi
centromere protein I
chr8_-_51340931 0.19 ENSDART00000178209
kansl3
KAT8 regulatory NSL complex subunit 3
chr6_-_19023468 0.19 ENSDART00000184729
sept9b
septin 9b
chr2_-_7696287 0.18 ENSDART00000190769
CABZ01055306.1

chr12_+_13348918 0.18 ENSDART00000181373
rnasen
ribonuclease type III, nuclear
chr23_-_7594723 0.18 ENSDART00000115298
plagl2
pleiomorphic adenoma gene-like 2
chr19_-_30800004 0.18 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
trit1
tRNA isopentenyltransferase 1
chr23_-_33944597 0.18 ENSDART00000133223
si:dkey-190g6.2
si:dkey-190g6.2
chr12_-_5188413 0.18 ENSDART00000161988
fra10ac1
FRA10A associated CGG repeat 1
chr4_+_34860183 0.17 ENSDART00000123281
ENSDART00000192960
ENSDART00000140637
ENSDART00000192576
ENSDART00000188148
znf985
zinc finger protein 985
chr7_-_41512999 0.17 ENSDART00000173577
si:dkey-10f23.2
si:dkey-10f23.2
chr14_-_28430505 0.17 ENSDART00000192373
nek12
NIMA-related kinase 12
chr16_+_26747766 0.17 ENSDART00000183257
rad54b
RAD54 homolog B (S. cerevisiae)
chr15_+_34963316 0.17 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr8_-_20862443 0.17 ENSDART00000147267
si:ch211-133l5.8
si:ch211-133l5.8
chr4_-_20135406 0.17 ENSDART00000161343
cep83
centrosomal protein 83
chr5_+_1965296 0.17 ENSDART00000156224
dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr5_+_36900157 0.16 ENSDART00000183533
ENSDART00000051184
hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr4_-_26035770 0.16 ENSDART00000124514
usp44
ubiquitin specific peptidase 44
chr18_+_8231138 0.16 ENSDART00000140193
arsa
arylsulfatase A
chr3_-_3703572 0.16 ENSDART00000111017
si:ch211-163m16.7
si:ch211-163m16.7
chr1_-_47071979 0.16 ENSDART00000160817
itsn1
intersectin 1 (SH3 domain protein)
chr1_+_5485799 0.16 ENSDART00000022307
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_+_26179096 0.16 ENSDART00000024662
plppr3a
phospholipid phosphatase related 3a
chr3_+_52999962 0.16 ENSDART00000104683
pbx4
pre-B-cell leukemia transcription factor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of sox4a+sox4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 0.8 GO:0016109 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 0.7 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.4 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.4 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 0.5 GO:0007412 axon target recognition(GO:0007412)
0.1 0.5 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 0.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.4 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.1 0.8 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.3 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.3 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.6 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.2 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.2 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081) myeloid leukocyte cytokine production(GO:0061082)
0.0 0.3 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.2 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.6 GO:0035329 hippo signaling(GO:0035329)
0.0 0.5 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.7 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 1.4 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 2.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0009749 response to glucose(GO:0009749)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.4 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.1 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.2 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.6 GO:0016575 histone deacetylation(GO:0016575)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0032301 MutSalpha complex(GO:0032301)
0.2 0.5 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.3 GO:0097361 CIA complex(GO:0097361)
0.1 0.4 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.6 GO:0016586 RSC complex(GO:0016586)
0.1 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.3 GO:0034359 mature chylomicron(GO:0034359)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0044545 NSL complex(GO:0044545)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.0 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 3.0 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0032404 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.2 0.8 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.2 0.5 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.5 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.1 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.6 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 5.3 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway