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PRJEB1986: zebrafish developmental stages transcriptome

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Results for sp3b

Z-value: 0.94

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Transcription factors associated with sp3b

Gene Symbol Gene ID Gene Info
sp3b
ENSDARG00000007812 Sp3b transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp3bdr11_v1_chr6_-_10740365_107403650.716.4e-04Click!

Activity profile of sp3b motif

Sorted Z-values of sp3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_77557279 3.98 ENSDART00000180113
AL935186.10

chr5_-_1047222 2.49 ENSDART00000181112
mbd2
methyl-CpG binding domain protein 2
chr13_+_1100197 2.05 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr3_-_62380146 1.95 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr2_+_58221163 1.95 ENSDART00000157939
FO704813.1

chr8_+_43056153 1.80 ENSDART00000186377
prnpa
prion protein a
chr14_-_2933185 1.54 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr17_+_12075805 1.47 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr8_+_1082100 1.46 ENSDART00000149276
lzts3b
leucine zipper, putative tumor suppressor family member 3b
chr6_-_60104628 1.31 ENSDART00000057463
ENSDART00000169188
pmepa1
prostate transmembrane protein, androgen induced 1
chr3_-_16227683 1.28 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr24_-_14711597 1.24 ENSDART00000131830
jph1a
junctophilin 1a
chr20_+_46741074 1.23 ENSDART00000145294
si:ch211-57i17.1
si:ch211-57i17.1
chr19_+_935565 1.20 ENSDART00000113368
RNF5
ring finger protein 5
chr25_+_16356083 1.20 ENSDART00000125925
ENSDART00000125444
tead1a
TEA domain family member 1a
chr4_+_3358383 1.18 ENSDART00000075320
nampta
nicotinamide phosphoribosyltransferase a
chr8_+_2656231 1.15 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr14_+_30910114 1.13 ENSDART00000187166
ENSDART00000078187
foxo4
forkhead box O4
chr21_+_1143141 1.12 ENSDART00000178294
CABZ01086139.1

chr10_-_641609 1.12 ENSDART00000041236
rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr7_+_74141297 1.08 ENSDART00000164992
rbpms
RNA binding protein with multiple splicing
chr3_+_49043917 1.05 ENSDART00000158212
zgc:92161
zgc:92161
chr13_-_17860307 1.04 ENSDART00000135920
ENSDART00000054579
march8
membrane-associated ring finger (C3HC4) 8
chr16_-_8120203 1.02 ENSDART00000193430
snrka
SNF related kinase a
chr23_-_30960506 1.01 ENSDART00000142661
osbpl2a
oxysterol binding protein-like 2a
chr25_-_35599887 1.01 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr21_-_39058490 1.01 ENSDART00000114885
aldh3a2b
aldehyde dehydrogenase 3 family, member A2b
chr13_+_3819475 1.01 ENSDART00000139958
qkib
QKI, KH domain containing, RNA binding b
chr7_-_6592142 1.01 ENSDART00000160137
kcnj10a
potassium inwardly-rectifying channel, subfamily J, member 10a
chr13_-_638485 1.01 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr8_+_6576940 1.00 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr6_-_58828398 0.97 ENSDART00000090634
kif5ab
kinesin family member 5A, b
chr19_+_156757 0.96 ENSDART00000167717
carmil1
capping protein regulator and myosin 1 linker 1
chr5_+_6617401 0.96 ENSDART00000060532
zgc:110796
zgc:110796
chr23_+_17220986 0.95 ENSDART00000054761
nol4lb
nucleolar protein 4-like b
chr20_+_13175379 0.94 ENSDART00000025644
ppp2r5a
protein phosphatase 2, regulatory subunit B', alpha isoform
chr15_-_47956388 0.93 ENSDART00000116506
si:ch1073-111c8.3
si:ch1073-111c8.3
chr7_-_61683417 0.93 ENSDART00000098622
ENSDART00000184088
ENSDART00000148270
lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr10_+_44924684 0.93 ENSDART00000181360
ENSDART00000170418
ENSDART00000170327
sec14l7
SEC14-like lipid binding 7
chr10_+_5135842 0.92 ENSDART00000132627
ENSDART00000162434
zgc:113274
zgc:113274
chr9_-_54840124 0.92 ENSDART00000137214
ENSDART00000085693
gpm6bb
glycoprotein M6Bb
chr2_-_44282796 0.92 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
mpz
myelin protein zero
chr4_-_68831753 0.91 ENSDART00000189170
si:dkey-264f17.1
si:dkey-264f17.1
chr2_+_24177190 0.91 ENSDART00000099546
map4l
microtubule associated protein 4 like
chr20_+_52389858 0.90 ENSDART00000185863
ENSDART00000166651
arhgap39
Rho GTPase activating protein 39
chr4_-_22671469 0.89 ENSDART00000050753
cd36
CD36 molecule (thrombospondin receptor)
chr2_+_48073972 0.89 ENSDART00000186442
klf6b
Kruppel-like factor 6b
chr2_+_258698 0.89 ENSDART00000181330
ENSDART00000181645
phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr16_+_34528409 0.88 ENSDART00000144718
paqr7b
progestin and adipoQ receptor family member VII, b
chr7_+_7630409 0.87 ENSDART00000172934
clcn3
chloride channel 3
chr6_-_38818582 0.86 ENSDART00000149833
cnga3a
cyclic nucleotide gated channel alpha 3a
chr3_-_58455289 0.86 ENSDART00000052179
cdr2a
cerebellar degeneration-related protein 2a
chr16_+_4838808 0.85 ENSDART00000179363
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr8_-_53490376 0.84 ENSDART00000158789
chdh
choline dehydrogenase
chr5_-_13086616 0.84 ENSDART00000051664
ypel1
yippee-like 1
chr4_+_55758103 0.83 ENSDART00000185964
CT583728.23

chr5_+_51443009 0.83 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr12_-_45349849 0.82 ENSDART00000183036
CABZ01068367.1
Danio rerio uncharacterized LOC100332446 (LOC100332446), mRNA.
chr25_-_30047477 0.81 ENSDART00000164859
CR759810.1

chr3_+_11548516 0.81 ENSDART00000059117
mmd
monocyte to macrophage differentiation-associated
chr23_+_45611649 0.80 ENSDART00000169521
dclk2b
doublecortin-like kinase 2b
chr6_+_2271559 0.80 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b
chr6_+_34511886 0.78 ENSDART00000179450
lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr20_+_48413712 0.78 ENSDART00000159983
CABZ01059119.1

chr7_+_67325933 0.78 ENSDART00000170575
ENSDART00000183342
nfat5b
nuclear factor of activated T cells 5b
chr8_+_8166285 0.77 ENSDART00000147940
plxnb3
plexin B3
chr3_+_12322170 0.77 ENSDART00000161227
glis2b
GLIS family zinc finger 2b
chr24_-_26622423 0.77 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr15_-_44601331 0.76 ENSDART00000161514
zgc:165508
zgc:165508
chr15_-_43768776 0.76 ENSDART00000170398
grm5b
glutamate receptor, metabotropic 5b
chr6_-_1874664 0.76 ENSDART00000007972
dlgap4b
discs, large (Drosophila) homolog-associated protein 4b
chr8_+_22485956 0.75 ENSDART00000099960
si:ch211-261n11.7
si:ch211-261n11.7
chr10_+_12517059 0.75 ENSDART00000081140
CT990561.1

chr23_-_900795 0.75 ENSDART00000190517
ENSDART00000182849
ENSDART00000111456
ENSDART00000185430
rbm10
RNA binding motif protein 10
chr10_+_33895315 0.73 ENSDART00000142881
fryb
furry homolog b (Drosophila)
chr9_-_33725972 0.73 ENSDART00000028225
mao
monoamine oxidase
chr12_+_49125510 0.72 ENSDART00000185804
FO704607.1

chr9_+_993477 0.72 ENSDART00000182045
CABZ01066921.1

chr2_-_4874966 0.72 ENSDART00000165296
tfr1a
transferrin receptor 1a
chr25_-_19395476 0.71 ENSDART00000182622
map1ab
microtubule-associated protein 1Ab
chr2_-_58075414 0.71 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr1_+_54677173 0.71 ENSDART00000114705
gprc5bb
G protein-coupled receptor, class C, group 5, member Bb
chr21_-_45891262 0.71 ENSDART00000169816
galnt10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr5_-_69041102 0.70 ENSDART00000161561
ank1a
ankyrin 1, erythrocytic a
chr1_+_9004719 0.69 ENSDART00000006211
ENSDART00000137211
prkcba
protein kinase C, beta a
chr4_-_23839789 0.68 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr9_+_36946340 0.68 ENSDART00000135281
si:dkey-3d4.3
si:dkey-3d4.3
chr3_+_32526799 0.68 ENSDART00000185755
si:ch73-367p23.2
si:ch73-367p23.2
chr16_+_4839078 0.67 ENSDART00000150111
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr16_-_53919115 0.67 ENSDART00000179533
fzd1
frizzled class receptor 1
chr5_+_72152813 0.66 ENSDART00000149910
abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr7_+_1579510 0.66 ENSDART00000190525
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr12_+_5530247 0.66 ENSDART00000114637
ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr6_-_8580857 0.65 ENSDART00000138858
ENSDART00000041142
myh11a
myosin, heavy chain 11a, smooth muscle
chr15_-_37543591 0.65 ENSDART00000180400
kmt2bb
lysine (K)-specific methyltransferase 2Bb
chr23_+_14217508 0.65 ENSDART00000143618
birc7
baculoviral IAP repeat containing 7
chr8_+_1187928 0.64 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr15_+_47582207 0.64 ENSDART00000159388
CABZ01087566.1

chr1_-_31505144 0.63 ENSDART00000087115
rims1b
regulating synaptic membrane exocytosis 1b
chr1_-_57501299 0.63 ENSDART00000080600
zgc:171470
zgc:171470
chr3_+_15550522 0.62 ENSDART00000136912
ENSDART00000176218
si:dkey-93n13.3
si:dkey-93n13.3
chr18_+_26086803 0.62 ENSDART00000187911
znf710a
zinc finger protein 710a
chr5_-_19861766 0.62 ENSDART00000088904
gltpa
glycolipid transfer protein a
chr6_-_58828113 0.61 ENSDART00000180934
kif5ab
kinesin family member 5A, b
chr1_+_6307305 0.61 ENSDART00000183870
LO018629.1

chr18_-_8030073 0.60 ENSDART00000151490
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr13_-_5978433 0.60 ENSDART00000102555
actr2b
ARP2 actin related protein 2b homolog
chr17_-_22048233 0.60 ENSDART00000155203
ttbk1b
tau tubulin kinase 1b
chr15_-_33925851 0.59 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr15_-_2726662 0.59 ENSDART00000108856
si:ch211-235m3.5
si:ch211-235m3.5
chr11_+_36989696 0.59 ENSDART00000045888
tkta
transketolase a
chr13_-_27767330 0.59 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
rims1a
regulating synaptic membrane exocytosis 1a
chr10_+_1638876 0.59 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
sgsm1b
small G protein signaling modulator 1b
chr21_-_32436679 0.58 ENSDART00000076974
gfpt2
glutamine-fructose-6-phosphate transaminase 2
chr13_-_51922290 0.57 ENSDART00000168648
srfb
serum response factor b
chr4_-_68569527 0.56 ENSDART00000192091
BX548011.5

chr5_-_71838520 0.56 ENSDART00000174396
CU927890.1

chr8_-_410728 0.55 ENSDART00000151255
trim36
tripartite motif containing 36
chr20_-_16972351 0.55 ENSDART00000148312
ENSDART00000186702
si:ch73-74h11.1
si:ch73-74h11.1
chr6_+_102506 0.55 ENSDART00000172678
ldlrb
low density lipoprotein receptor b
chr22_-_7563593 0.54 ENSDART00000106062
BX511034.1

chr3_+_59851537 0.54 ENSDART00000180997
CU693479.1

chr7_-_55454406 0.54 ENSDART00000108646
piezo1
piezo-type mechanosensitive ion channel component 1
chr13_-_21739142 0.54 ENSDART00000078460
si:dkey-191g9.5
si:dkey-191g9.5
chr19_+_342094 0.53 ENSDART00000151013
ENSDART00000187622
ensaa
endosulfine alpha a
chr16_-_280835 0.53 ENSDART00000190541
LO017917.1

chr25_+_4581214 0.53 ENSDART00000185552
CABZ01068600.1

chr25_-_36492779 0.52 ENSDART00000042271
irx3b
iroquois homeobox 3b
chr8_+_28900689 0.52 ENSDART00000141634
grid2
glutamate receptor, ionotropic, delta 2
chr22_+_883678 0.52 ENSDART00000140588
stk38b
serine/threonine kinase 38b
chr25_+_336503 0.52 ENSDART00000160395
CU929262.1

chr19_-_6193448 0.52 ENSDART00000151405
erf
Ets2 repressor factor
chr18_-_46763170 0.52 ENSDART00000171880
dner
delta/notch-like EGF repeat containing
chr11_+_45287541 0.51 ENSDART00000165321
ENSDART00000173116
pycr1b
pyrroline-5-carboxylate reductase 1b
chr19_-_44091405 0.51 ENSDART00000132800
rad21b
RAD21 cohesin complex component b
chr20_-_33675676 0.51 ENSDART00000147168
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr17_+_25856671 0.50 ENSDART00000064817
wapla
WAPL cohesin release factor a
chr25_+_34407529 0.50 ENSDART00000156751
OTUD7A
si:dkey-37f18.2
chr5_-_14326959 0.50 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr22_-_34979139 0.50 ENSDART00000116455
ENSDART00000133537
arhgap19
Rho GTPase activating protein 19
chr8_-_22739757 0.50 ENSDART00000182167
ENSDART00000171891
iqsec2a
IQ motif and Sec7 domain 2a
chr7_-_23768234 0.50 ENSDART00000173981
si:ch211-200p22.4
si:ch211-200p22.4
chr15_+_20543770 0.50 ENSDART00000092357
sgsm2
small G protein signaling modulator 2
chr3_-_18274691 0.50 ENSDART00000161140
BX649434.3

chr21_-_45086170 0.50 ENSDART00000188963
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr3_+_40841897 0.50 ENSDART00000150081
ENSDART00000126096
mmd2a
monocyte to macrophage differentiation-associated 2a
chr8_+_48965767 0.49 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr25_+_37443194 0.49 ENSDART00000163178
ENSDART00000190262
slc10a3
solute carrier family 10, member 3
chr20_+_39250673 0.49 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr22_-_607812 0.48 ENSDART00000145983
cdkn1a
cyclin-dependent kinase inhibitor 1A
chr10_+_44719697 0.48 ENSDART00000158087
scarb1
scavenger receptor class B, member 1
chr19_-_22498629 0.48 ENSDART00000185370
pleca
plectin a
chr18_-_14941840 0.48 ENSDART00000091729
mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr25_+_35706493 0.47 ENSDART00000176741
kif21a
kinesin family member 21A
chr18_+_660578 0.47 ENSDART00000161203
CELF6
si:dkey-205h23.2
chr15_-_17025212 0.47 ENSDART00000014465
hip1
huntingtin interacting protein 1
chr9_+_30274637 0.46 ENSDART00000079095
rpgra
retinitis pigmentosa GTPase regulator a
chr18_+_507835 0.46 ENSDART00000189701
nedd4a
neural precursor cell expressed, developmentally down-regulated 4a
chr3_-_5964557 0.46 ENSDART00000184738
BX284638.1

chr9_-_2572790 0.46 ENSDART00000135076
ENSDART00000016710
scrn3
secernin 3
chr6_-_21830405 0.46 ENSDART00000151803
ENSDART00000113497
setd5
SET domain containing 5
chr7_-_5148388 0.46 ENSDART00000143549
si:ch211-272h9.5
si:ch211-272h9.5
chr17_-_2721336 0.46 ENSDART00000109582
ENSDART00000192691
ENSDART00000189381
spata7
spermatogenesis associated 7
chr10_+_10210455 0.46 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr8_+_29963024 0.46 ENSDART00000149372
ptch1
patched 1
chr21_+_28445052 0.45 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr15_+_45544589 0.45 ENSDART00000055978
LO018197.1

chr9_+_55154414 0.45 ENSDART00000182924
ANOS1
anosmin 1
chr23_-_1660708 0.45 ENSDART00000175138
CU693481.1

chr6_+_48206535 0.45 ENSDART00000075172
cttnbp2nla
CTTNBP2 N-terminal like a
chr17_+_44756247 0.44 ENSDART00000153773
cipca
CLOCK-interacting pacemaker a
chr4_-_37766174 0.44 ENSDART00000170066
si:dkey-207l24.2
si:dkey-207l24.2
chr3_+_22079219 0.44 ENSDART00000122782
kansl1b
KAT8 regulatory NSL complex subunit 1b
chr20_-_22378401 0.44 ENSDART00000011135
ENSDART00000110967
kita
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
chr8_-_5847533 0.43 ENSDART00000192489
CABZ01102147.1

chr22_-_18112374 0.43 ENSDART00000191154
ncanb
neurocan b
chr8_+_51958968 0.43 ENSDART00000139509
ENSDART00000186544
gna14a
guanine nucleotide binding protein (G protein), alpha 14a
chr2_+_43469241 0.43 ENSDART00000142078
ENSDART00000098265
nrp1b
neuropilin 1b
chr2_+_24177006 0.43 ENSDART00000132582
map4l
microtubule associated protein 4 like
chr8_-_53488832 0.43 ENSDART00000191801
chdh
choline dehydrogenase
chr14_+_15620640 0.43 ENSDART00000188867
si:dkey-203a12.9
si:dkey-203a12.9
chr8_+_7740004 0.43 ENSDART00000170184
ENSDART00000187811
fgd1
FYVE, RhoGEF and PH domain containing 1
chr1_+_24469313 0.42 ENSDART00000176581
fam160a1a
family with sequence similarity 160, member A1a
chr5_-_5243079 0.42 ENSDART00000130576
ENSDART00000164377
mvb12ba
multivesicular body subunit 12Ba
chr24_+_40473032 0.42 ENSDART00000084238
ENSDART00000178508
CABZ01076968.1

chr5_-_30074332 0.41 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr9_+_15890558 0.41 ENSDART00000144032
si:dkey-14o1.20
si:dkey-14o1.20
chr15_-_14552101 0.41 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr4_+_3980247 0.41 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr6_+_48862 0.41 ENSDART00000082954
mbd5
methyl-CpG binding domain protein 5
chr9_-_11263228 0.41 ENSDART00000113847
chpfa
chondroitin polymerizing factor a
chr16_-_8613499 0.41 ENSDART00000189189
cobl
cordon-bleu WH2 repeat protein
chr25_-_10724947 0.40 ENSDART00000184490
lrp5
low density lipoprotein receptor-related protein 5
chr16_-_52733384 0.40 ENSDART00000147236
ENSDART00000056101
azin1a
antizyme inhibitor 1a
chr11_-_44030962 0.40 ENSDART00000171910
FP016005.1

chr14_-_448182 0.40 ENSDART00000180018
FAT4
FAT atypical cadherin 4
chr8_+_48966165 0.40 ENSDART00000165425
aak1a
AP2 associated kinase 1a
chr6_+_58915889 0.40 ENSDART00000083628
ddit3
DNA-damage-inducible transcript 3
chr16_-_20707742 0.39 ENSDART00000103630
creb5b
cAMP responsive element binding protein 5b
chr4_+_5537101 0.39 ENSDART00000008692
si:dkey-14d8.7
si:dkey-14d8.7

Network of associatons between targets according to the STRING database.

First level regulatory network of sp3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 1.3 GO:0019695 choline metabolic process(GO:0019695)
0.4 1.1 GO:0051580 regulation of neurotransmitter uptake(GO:0051580)
0.3 1.0 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.3 0.3 GO:1905067 negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.3 1.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3 0.8 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 1.6 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 1.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2 0.7 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.2 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.2 0.5 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.2 0.5 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.2 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 0.5 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.1 0.6 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 1.0 GO:0036268 swimming(GO:0036268)
0.1 0.3 GO:0051610 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.1 0.4 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.1 0.8 GO:0003272 endocardial cushion formation(GO:0003272)
0.1 0.9 GO:0034381 plasma lipoprotein particle clearance(GO:0034381)
0.1 0.4 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.8 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.7 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.4 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.5 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.4 GO:1902590 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.1 0.5 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 1.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 1.0 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 0.8 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 0.1 GO:0098773 skin epidermis development(GO:0098773)
0.1 0.7 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.7 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.3 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.6 GO:2001032 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 1.6 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.9 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 1.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.5 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 0.2 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 1.1 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.4 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 0.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.8 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.4 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.5 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.3 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.0 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 1.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.0 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.5 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.9 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.8 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.8 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.4 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.4 GO:0061384 trabecula morphogenesis(GO:0061383) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.8 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.4 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0010165 response to X-ray(GO:0010165)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.2 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:1900044 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.2 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.5 GO:0019835 cytolysis(GO:0019835)
0.0 0.5 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.1 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.0 0.0 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 1.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.2 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.3 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.2 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0070062 extracellular exosome(GO:0070062)
0.2 1.2 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.8 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 0.4 GO:0010369 chromocenter(GO:0010369)
0.1 0.9 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.5 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 3.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.4 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.7 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 1.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.6 GO:0042383 sarcolemma(GO:0042383)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 2.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.7 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 1.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.8 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.8 GO:0030027 lamellipodium(GO:0030027)
0.0 0.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0071253 connexin binding(GO:0071253)
0.3 1.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.8 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.8 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 0.7 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.6 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.6 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.8 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.3 GO:0015222 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.1 0.5 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.4 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.7 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.9 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.1 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.0 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 2.1 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 1.0 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.7 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 1.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.6 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.8 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 1.3 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination